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3-bromo-7-Nitroindazole

Cayman Chemical Item Number 81345

(CAS 74209-34-0)

3-bromo-7-Nitroindazole (CAS 74209-34-0)

See more	Nitric Oxide (101)

Description

3-Bromo-7-nitroindazole is a more potent inhibitor of nNOS than 7-nitroindazole in vitro, but unlike 7-nitroindazole, it is also potent against iNOS. The IC₅₀ values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.17, 0.86, and 0.29 µM, respectively.¹

1 Bland-Ward, P.A., Pitcher, A., Wallace, P., et al. Isoform selectivity of indazole-based nitric oxide synthase inhibitors. Br J Pharmacol 112 351P (1994).

Formal Name	3-bromo-7-nitro-1H-indazole
CAS Number	74209-34-0
Molecular Formula	C₇H₄BrN₃O₂
Formula Weight	242.0
Formulation	A crystalline solid
Purity	>98%
λ_max	232, 361 nm
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard O[N](=O)c1cccc2c(Br)n[nH]c12

Background Reading

Bland-Ward, P.A., Pitcher, A., Wallace, P., et al. Isoform selectivity of indazole-based nitric oxide synthase inhibitors. Br J Pharmacol 112 351P (1994).

3-bromo-7-Nitroindazole is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
50 mg	$66.00		$0.00
100 mg	$125.00		$0.00
250 mg	$297.00		$0.00
500 mg	$528.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-11. Prices are subject to change without notice.

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Related Products

7-Nitroindazole

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