81410  ODQ

(CAS 41443-28-1)

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Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

ODQ is a highly selective, irreversible, heme-site inhibitor of soluble guanylyl cyclase.1,2 The binding of ODQ is competitive with NO. The inhibition of soluble guanylyl cyclase is time dependent with complete inactivation in 10 minutes at 0.3 µM ODQ.2
1  Garthwaite, J., Southam, E., Boulton, C.L., et al. Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one. Mol Pharmacol 48 184-188 (1995).
2  Schrammel, A., Behrends, S., Schmidt, K., et al. Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylyl cyclase. Mol Pharmacol 50 1-5 (1996).


Purchase 81410 ODQ

Pricing is for North America only. Other customers should contact a distributor in their region.

This product is also available to buy in bulk quantities. Please contact our Sales Department for a quote or to purchase.

Cayman strives to be a reliable biochemical reagent vendor by providing the best possible products and services. To ask for assistance with one of our products please contact our Technical Help staff.

Warning This product is not for human or veterinary use.

Pricing updated 2010-03-14.
Prices are subject to change without notice.

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