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Carboxy-PTIO (potassium salt)

Cayman Chemical Item Number 81540

(CAS 148819-94-7)

Carboxy-PTIO (potassium salt) (CAS 148819-94-7)

See more	Nitric Oxide (101)

Description

Carboxy-PTIO is a NO scavenger. It reacts stoichiometrically with NO and can be used for EPR detection of NO.^1,2

1 Akaike, T., Yoshida, M., Miyamoto, Y., et al. Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/·NO through a radical reaction. Biochemistry 32 827-832 (1993).

2 Pfeiffer, S., Leopold, E., Hemmens, B., et al. Interference of carboxy-PTIO with nitric oxide-and peroxynitrite-mediated reactions. Free Radic Biol Med 22 787-794 (1997).

Formal Name	2-(4-carboxyphenyl)-4,5-dihydro-4,4,5,5-tetramethyl-1H-imidazolyl-1-oxy-3-oxide, monopotassium salt
CAS Number	148819-94-7
Molecular Formula	C₁₄H₁₆N₂O₄ · K
Formula Weight	315.4
Formulation	A crystalline solid
Purity	>99%
λ_max	232, 282, 368 nm
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard [O-][N+]1=C(C2=CC=C(C([O-])=O)C=C2)N([O-])C(C)(C)C1(C)C.[K+]

Background Reading

Akaike, T., Yoshida, M., Miyamoto, Y., et al. Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/·NO through a radical reaction. Biochemistry 32 827-832 (1993).

Pfeiffer, S., Leopold, E., Hemmens, B., et al. Interference of carboxy-PTIO with nitric oxide-and peroxynitrite-mediated reactions. Free Radic Biol Med 22 787-794 (1997).

Size	Global Purchasing
5 mg	See a distributor in your region for pricing
10 mg	See a distributor in your region for pricing
50 mg	See a distributor in your region for pricing
100 mg	See a distributor in your region for pricing

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