DPTA NONOate
Cayman Chemical Item Number 82110
Dipropylenetriamine NONOate
(CAS 146724-95-0)
DPTA NONOate
(CAS 146724-95-0)
Description
DPTA NONOate is a NO donor. It spontaneously dissociates in a pH- dependent, first- order process with a half- life of three hours and five hours at 37°C and 22- 25°C, pH 7.4, respectively, to liberate 2 moles of NO per mole of parent compound. 1 ,2
1
Hrabie, J.A., Klose, J.R., Wink, D.A., et al . New nitric oxide- releasing zwitterions derived from polyamines . J Org Chem 58 1472-1476 (1993) .
2
Keefer, L.K., Nims, R.W., Davies, K.M., et al . “NONOates” (1- substituted diazen- 1- ium- 1,2- diolates) as nitric oxide donors: Convenient nitric oxide dosage forms . Methods Enzymol 268 281-293 (1996) .
Synonyms
Dipropylenetriamine NONOate
Formal Name
(Z)-1-[N-(3-aminopropyl)-N-(3-ammoniopropyl)amino]diazen-1-ium-1,2-diolate
CAS Number
146724-95-0
Molecular Formula
C6 H17 N5 O2
Formula Weight
191.2
Formulation
A crystalline solid
Purity
≥98%
λmax
252 nm
ε
7
Stability
1 year
Storage
-80°C
Shipping
Dry ice
in continental US; may vary elsewhere
SMILES
Copy
NCCCN(CCCN)N(O)N=O
Background Reading
Hrabie, J.A., Klose, J.R., Wink, D.A., et al . New nitric oxide- releasing zwitterions derived from polyamines . J Org Chem 58 1472-1476 (1993) .
Keefer, L.K., Nims, R.W., Davies, K.M., et al . “NONOates” (1- substituted diazen- 1- ium- 1,2- diolates) as nitric oxide donors: Convenient nitric oxide dosage forms . Methods Enzymol 268 281-293 (1996) .
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