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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

PROLI NONOate

Cayman Chemical Item Number 82145

PROLI NONOate

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Description

PROLI NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 1.8 seconds at 37°C (pH 7.4) to liberate 2 moles of NO per mole of parent compound.1

1 Saavedra, J.E., Southan, G.J., Davies, K.M., et al. Localizing antithrombotic and vasodilatory activity with a novel, ultrafast nitric oxide donor. J Med Chem 39 4361-4365 (1996).

Formal Name 1-​(hydroxy-​NNO-​azoxy)-​L-​proline,​ disodium salt
Molecular Formula C5H7N3O4 · 2Na
Formula Weight 219.1
Formulation A crystalline solid
Purity >98%
λmax 252 nm
ε 8
Stability 1 year
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
SMILES
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[O-]​[N+]​(N1[C@H]​(C([O-]​)​=O)​CCC1)​=N[O-]​.[2Na+]​

Background Reading

Maragos, C.M., Morley, D., Wink, D.A., et al. Complexes of ·NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects. J Med Chem 34 3242-3247 (1991).

Saavedra, J.E., Southan, G.J., Davies, K.M., et al. Localizing antithrombotic and vasodilatory activity with a novel, ultrafast nitric oxide donor. J Med Chem 39 4361-4365 (1996).

PROLI NONOate is available in the following screening library:

Size Price Quantity Subtotal
10 mg $22.00 $0.00
50 mg $99.00 $0.00
100 mg $176.00 $0.00
500 mg $770.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-11. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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