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V-PYRRO/NO

Cayman Chemical Item Number 82160

(CAS 179344-98-0)

V-PYRRO/NO (CAS 179344-98-0)

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Description

V-PYRRO/NO is a NO donor in vivo. Following hepatic metabolism, it spontaneously decomposes with a half-life of 3 seconds to liberate NO.1

1 Saavedra, J.E., Billiar, T.R., Williams, D.L., et al. Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-α-induced apoptosis and toxicity in the liver. J Med Chem 40 1947-1954 (1997).

Formal Name 1-​[(ethenyloxy)-​NNO-​azoxy]-​pyrrolidine
CAS Number 179344-98-0
Molecular Formula C6H11N3O2
Formula Weight 157.2
Formulation A solution in ethanol
Purity >98%
λmax 268 nm
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CON(=C)​=[N]​(O)​N1CCCC1

Background Reading

Saavedra, J.E., Billiar, T.R., Williams, D.L., et al. Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-α-induced apoptosis and toxicity in the liver. J Med Chem 40 1947-1954 (1997).

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