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Molsidomine

Cayman Chemical Item Number 82200

Morsydomine; Corvaton (CAS 25717-80-0)

Molsidomine (CAS 25717-80-0)

See more	NO Donors (26) Nitric Oxide (101)

Description

Molsidomine is a NO-releasing prodrug. Liver esterases convert molsidomine to the active metabolite, SIN-1 (half-life in plasma is 1-2 hours), which then releases NO.^1,2

1 Nitz, R., and Fiedler, V. Molsidomine: Alternative approaches to treat myocardial ischemia. Pharmacotherapy 7 28-37 (1987).

2 Rosenkranz, B., Winkelmann, B.R., and Parnham, M.J. Clinical pharmacokinetics of molsidomine. Clin Pharmacokinet 30 372-384 (1996).

Synonyms	Morsydomine Corvaton
Formal Name	N-(ethoxycarbonyl)-3-(4-morpholinyl)-sydnone imine
CAS Number	25717-80-0
Molecular Formula	C₉H₁₄N₄O₄
Formula Weight	242.2
Formulation	A crystalline solid
Purity	>99%
λ_max	230, 319 nm
Stability	1 year
Storage	Room temperature
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard [H]N(C(OCC)=O)C1=C[N](N2CCOCC2)=NO1

Background Reading

Nitz, R., and Fiedler, V. Molsidomine: Alternative approaches to treat myocardial ischemia. Pharmacotherapy 7 28-37 (1987).

Rosenkranz, B., Winkelmann, B.R., and Parnham, M.J. Clinical pharmacokinetics of molsidomine. Clin Pharmacokinet 30 372-384 (1996).

Molsidomine is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Global Purchasing
100 mg	See a distributor in your region for pricing
500 mg	See a distributor in your region for pricing
1 g	See a distributor in your region for pricing
5 g	See a distributor in your region for pricing

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Warning This product is not for human or veterinary use.

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