The ω-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Stearidonic acid is an ω-3 C18:4 PUFA. It is an intermediate in the metabolic pathway leading from α-linolenic acid ( ALA) to eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).1 Dietary stearidonic acid increases tissue levels of EPA better than does dietary ALA.2 Stearidonoyl glycine consists of glycine attached at the carboxy terminus.
1
Guil-Guerrero, J.L. Stearidonic acid (18:4n-3): Metabolism, nutritional importance, medical uses and natural sources. Eur J Lipid Sci Technol1091226-1236(2007).
2
James, M.J., Ursin, V.M., and Cleland, L.G. Metabolism of stearidonic acid in human subjects: Comparison with the metabolism of other n-3 fatty acids. Am J Clin Nutr771140-1145(2003).
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CC/C=C\C/C=C\C/C=C\C/C=C\CCCCC(=O)NCC(=O)O
Background Reading
Guil-Guerrero, J.L. Stearidonic acid (18:4n-3): Metabolism, nutritional importance, medical uses and natural sources. Eur J Lipid Sci Technol1091226-1236(2007).
James, M.J., Ursin, V.M., and Cleland, L.G. Metabolism of stearidonic acid in human subjects: Comparison with the metabolism of other n-3 fatty acids. Am J Clin Nutr771140-1145(2003).
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