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Palmitoyl Ethanolamide-d₄ Exclusive

Cayman Chemical Item Number 9000551

Palmidrol-d₄; PEA-hydroxyethyl-1,1,2,2-d₄

Palmitoyl Ethanolamide-d4

See more	Mass Spectrometry (253) Endocannabinoids (54) Fatty Acids (267) Neuroscience (654)

Description

Palmitoyl ethanolamide (PEA) is an endogenous cannabinoid found in brain, liver, and other mammalian tissues.¹ PEA has also been isolated from egg yolk, and found to have anti-anaphylactic and anti-inflammatory activity in vitro.² PEA is an endocannabinoid which has been shown to significantly elevate cAMP in cells expressing CB₂ receptors. However, its affinity for CB₂ receptors is relatively low, at about 10 µM. CB₁ receptors have no appreciable affinity for PEA.³

1 Bachur, N.R., Masek, K., Melmon, K.L., et al. Fatty acid amides of ethanolamine in mammalian tissues. J Biol Chem 240 1019-1024 (1965).

2 Ganley, O.H., Graessle, O.E., Robinson, H.J., et al. Anti-inflammatory activity of compounds obtained from egg yolk, peanut oil, and soybean lecithin. J Lab Clin Med 51 709-714 (1958).

3 Devane, W.A., Hanus, L., Breuer, A., et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258 1946-1949 (1992).

Synonyms	Palmidrol-d4 PEA-hydroxyethyl-1,1,2,2-d4
Formal Name	N-(2-hydroxyethyl-1,1,2,2-d4)-hexadecanamide
Molecular Formula	C₁₈H₃₃D₄NO₂
Formula Weight	303.5
Formulation	A solution in ethanol
Purity	≥99% deuterated product
Stability	1 year
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard OC([2H])([2H])C([2H])([2H])N([H])C(CCCCCCCCCCCCCCC)=O

Background Reading

Devane, W.A., Hanus, L., Breuer, A., et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258 1946-1949 (1992).

Size	Price	Quantity	Subtotal
100 µg	$28.00		$0.00
500 µg	$126.00		$0.00
1 mg	$224.00		$0.00
5 mg	$980.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

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Palmitoyl Ethanolamide-d4 Exclusive