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JWH 203

Cayman Chemical Item Number 9000736

(CAS 864445-54-5)

JWH 203 (CAS 864445-54-5)

See more	Cannabinoids (333) Forensic Science (369) Neuroscience (725) Pain (151)

Description

JWH 203 is an analgesic chemical from the phenylacetylindole family that acts as a cannabinoid (CB) agonist with K_i values of 8.0 and 7.0 nM at the CB₁ and CB₂ receptors, respectively.¹ Similar to the related 2'-methoxy compound JWH 250, JWH 203 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole CB compounds. Compared to JWH 250, JWH 203 displays slightly more potent binding affinities for the CB₁ and CB₂ receptors (JWH 250 K_is = 11 and 33 nM, respectively).¹

1 Huffman, J.W., Szklennik, P.V., Almond, A., et al. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg Med Chem Lett 15 4110-4113 (2005).

Formal Name	2-(2-chlorophenyl)-1-(1-pentyl-1H-indol-3-yl)-ethanone
CAS Number	864445-54-5
Molecular Formula	C₂₁H₂₂ClNO
Formula Weight	339.9
Formulation	A crystalline solid
Purity	≥98%
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCN1C=C(C(CC2=C(Cl)C=CC=C2)=O)C3=CC=CC=C31

JWH 203 is available in the following screening library:

Cannabinoid Agonist Screening Library (96-Well)

Size	Global Purchasing
5 mg	See a distributor in your region for pricing
10 mg	See a distributor in your region for pricing
25 mg	See a distributor in your region for pricing

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Featured Products	Mojo
RCS-8 A synthetic cannabinoid	98.138615251861
JWH 250 High-affinity CB receptor agonist	81.333491122734
JWH 302 Exclusive A synthetic CB	58.664660429136
JWH 251 A synthetic cannabinoid	44.132323069158
JWH 201 Exclusive Synthetic CB	52.971855179095

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