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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

JWH 073 4-hydroxyindole metabolite

Cayman Chemical Item Number 9000861

JWH 073 4-hydroxyindole metabolite

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Description

JWH 073 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole WIN 55212-2. The Ki values for binding CB1 and the peripheral cannabinoid (CB2) receptor are 8.9 and 38 nM, respectively for a CB1:CB2 ratio of 0.23.1 JWH 073 is one of several synthetic CBs which have been included in smoking mixtures. JWH 073 4-hydroxyindole metabolite is expected to be a urinary metabolite of JWH 073 based on the metabolism of the closely-related JWH 015 and JWH 018.2,3

1 Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend 60 133-140 (2000).

2 Zhang, Q., Ma, P., Cole, R.B., et al. Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS. Anal Bioanal Chem 386 1345-1355 (2006).

3 Sobolevsky, T., Prasolov, I., and Rodchenkov, G. Detection of JWH-018 metabolites in smoking mixture post-administration urine. Forensic Sci Int 200 141-147 (2010).

Formal Name (1-​butyl-​4-​hydroxy-​1H-​indol-​3-​yl)(naphthalen-​1-​yl)-​methanone
Molecular Formula C23H21NO2
Formula Weight 343.4
Formulation A solution in ethanol
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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O=C(C1=CN(CCCC)​C2=C1C(O)​=CC=C2)​C3=C4C(C=CC=C4)​=CC=C3
Size Price Quantity Subtotal
1 mg $112.00 $0.00
5 mg $504.00 $0.00
10 mg $896.00 $0.00
Bulk Contact
Cart Total $0.00

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Pricing updated 2012-02-12. Prices are subject to change without notice.

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Warning This product is not for human or veterinary use.

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JWH 073 2-hydroxyindole metabolite
JWH 073 2-hydroxyindole metabolite-d7 Exclusive
JWH 073 2-methylnaphthyl analog New Exclusive
JWH 073 2'-naphthyl-N-(1,1-dimethylethyl) isomer New
JWH 073 4-hydroxyindole metabolite-d7 Exclusive
JWH 073 5-hydroxyindole metabolite Exclusive
JWH 073 5-hydroxyindole metabolite-d7 Exclusive
JWH 073 6-hydroxyindole metabolite Exclusive
JWH 073 6-hydroxyindole metabolite-d7 Exclusive
JWH 073 7-hydroxyindole metabolite Exclusive
JWH 073-d7 (solution) Exclusive
JWH 073 N-(1,1-dimethylethyl) isomer New
JWH 073 N-(4-hydroxybutyl) metabolite Exclusive
JWH 073 N-butanoic acid metabolite Exclusive
JWH 073 N-butanoic acid metabolite-d5 Exclusive
JWH 073 (solution)
JWH 370 New
RCS-8 Exclusive
(R)-(−)-JWH 073 N-(3-hydroxybutyl) metabolite New
(S)-(+)-JWH 073 N-(3-hydroxybutyl) metabolite New
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