See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!

Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

JWH 073 5-hydroxyindole metabolite Exclusive

Cayman Chemical Item Number 9000862

JWH 073 5-hydroxyindole metabolite

See more

Description

JWH 073 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole WIN 55212-2. The Ki values for binding CB1 and the peripheral cannabinoid (CB2) receptor are 8.9 and 38 nM, respectively for a CB1:CB2 ratio of 0.23.1 JWH 073 is one of several synthetic CBs which have been included in smoking mixtures. JWH 073 5-hydroxyindole metabolite is expected to be a urinary metabolite of JWH 073 based on the metabolism of the closely-related JWH 015 and JWH 018.2,3

1 Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend 60 133-140 (2000).

2 Zhang, Q., Ma, P., Cole, R.B., et al. Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS. Anal Bioanal Chem 386 1345-1355 (2006).

3 Sobolevsky, T., Prasolov, I., and Rodchenkov, G. Detection of JWH-018 metabolites in smoking mixture post-administration urine. Forensic Sci Int 200 141-147 (2010).

Formal Name (1-​butyl-​5-​hydroxy-​1H-​indol-​3-​yl)(naphthalen-​1-​yl)-​methanone
Molecular Formula C23H21NO2
Formula Weight 343.4
Formulation A crystalline solid
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
O=C(C1=CN(CCCC)​C2=C1C=C(O)​C=C2)​C3=C4C(C=CC=C4)​=CC=C3

Background Reading

Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend 60 133-140 (2000).

Zhang, Q., Ma, P., Cole, R.B., et al. Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS. Anal Bioanal Chem 386 1345-1355 (2006).

Sobolevsky, T., Prasolov, I., and Rodchenkov, G. Detection of JWH-018 metabolites in smoking mixture post-administration urine. Forensic Sci Int 200 141-147 (2010).
Size Price Quantity Subtotal
1 mg $112.00 $0.00
5 mg $504.00 $0.00
10 mg $896.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

JWH 073
JWH 073 2-hydroxyindole metabolite
JWH 073 2-hydroxyindole metabolite-d7 Exclusive
JWH 073 2-methylnaphthyl analog New Exclusive
JWH 073 2'-naphthyl-N-(1,1-dimethylethyl) isomer New
JWH 073 4-hydroxyindole metabolite
JWH 073 4-hydroxyindole metabolite-d7 Exclusive
JWH 073 5-hydroxyindole metabolite-d7 Exclusive
JWH 073 6-hydroxyindole metabolite Exclusive
JWH 073 6-hydroxyindole metabolite-d7 Exclusive
JWH 073 7-hydroxyindole metabolite Exclusive
JWH 073-d7 (solution) Exclusive
JWH 073 N-(1,1-dimethylethyl) isomer New
JWH 073 N-(4-hydroxybutyl) metabolite Exclusive
JWH 073 N-butanoic acid metabolite Exclusive
JWH 073 N-butanoic acid metabolite-d5 Exclusive
JWH 073 (solution)
JWH 210 5-hydroxyindole metabolite Exclusive
RCS-8 Exclusive
(R)-(−)-JWH 073 N-(3-hydroxybutyl) metabolite New
(S)-(+)-JWH 073 N-(3-hydroxybutyl) metabolite New
Show all 21 Hide all but first 3

Downloads

Batch-specific Information

Login to access batch-specific information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

Lost password?