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JWH 073-d7 (solution) Exclusive

Cayman Chemical Item Number 9000868

JWH 073-d7 (solution)

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Description

JWH 073-d7 contains seven deuterium atoms at the 2, 2’, 3, 3’, 4, 4, and 4' positions. It is intended for use as an internal standard for the quantification of JWH 073 by GC- or LC-mass spectrometry (MS). JWH 073 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding CB1 and the peripheral cannabinoid (CB2) receptor are 8.9 and 38 nM, respectively for a CB1:CB2 ratio of 0.23.1 Its effects on suppression of spontaneous activity, maximum possible antinociceptive effect in the tail-flick assay, and rectal temperature are comparable to those of WIN 55212-2 when tested in rats.2

1 Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend 60 133-140 (2000).

2 Wiley, J.L., Compton, D.R., Dai, D., et al. Structure-activity relationships of indole- and pyrrole-derived cannabinoids. J Pharmacol Exp Ther 285(3) 995-1004 (1998).

Formal Name (1-​butyl-​1H-​indol-​3-​yl)-​1-​naphthalenyl-​2,​2,​3,​3,​4,​4,​4-​d7-​methanone
Molecular Formula C23H14D7NO
Formula Weight 334.5
Formulation A solution in methanol
Purity ≥99% deuterated forms (d1-d7)
λmax 218, 246, 315 nm
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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O=C(C1=CN(CC([2H]​)​([2H]​)​C([2H]​)​([2H]​)​C([2H]​)​([2H]​)​[2H]​)​C2=C1C=CC=C2)​C3=CC=CC4=CC=CC=C43

Background Reading

Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding. Drug Alcohol Depend 60 133-140 (2000).

Wiley, J.L., Compton, D.R., Dai, D., et al. Structure-activity relationships of indole- and pyrrole-derived cannabinoids. J Pharmacol Exp Ther 285(3) 995-1004 (1998).

Size Global Purchasing
500 µg See a distributor in your region for pricing
1 mg See a distributor in your region for pricing
5 mg See a distributor in your region for pricing

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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JWH 073 2-hydroxyindole metabolite
JWH 073 2-hydroxyindole metabolite-d7 Exclusive
JWH 073 2-methylnaphthyl analog Exclusive
JWH 073 2'-naphthyl isomer Exclusive
JWH 073 2'-naphthyl-N-(1,1-dimethylethyl) isomer New Exclusive
JWH 073 2'-naphthyl-N-(1-methylpropyl) isomer Exclusive
JWH 073 2'-naphthyl-N-(2-methylpropyl) isomer Exclusive
JWH 073 4-hydroxyindole metabolite
JWH 073 4-hydroxyindole metabolite-d7 Exclusive
JWH 073 4-methylnaphthyl analog
JWH 073 5-hydroxyindole metabolite Exclusive
JWH 073 5-hydroxyindole metabolite-d7 Exclusive
JWH 073 6-hydroxyindole metabolite Exclusive
JWH 073 6-hydroxyindole metabolite-d7 Exclusive
JWH 073 7-hydroxyindole metabolite Exclusive
JWH 073 N-(1,1-dimethylethyl) isomer New Exclusive
JWH 073 N-(1-methylpropyl) isomer Exclusive
JWH 073 N-(2-methylpropyl) isomer Exclusive
(±)-JWH 073 N-(3-hydroxybutyl) metabolite Exclusive
(±)-JWH 073 N-(3-hydroxybutyl) metabolite-d5 Exclusive
JWH 073 N-(4-hydroxybutyl) metabolite Exclusive
JWH 073 N-butanoic acid metabolite Exclusive
JWH 073 N-butanoic acid metabolite-d5 Exclusive
JWH 073 (solution)
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JWH 122 N-(5-hydroxypentyl) metabolite Exclusive
JWH 182 Exclusive
JWH 200-d5 (solution)
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JWH 250-d5 Exclusive
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(R)-AM1241 Exclusive
RCS-4
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(+)WIN 55212-2 (mesylate)
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Batch-specific Information

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FAQs

It appears that there is a heterogenous mixture of deuterated species in your deuterated standards; is this normal?

Yes, this is typical of our deuterated products. Our deuterated products contain less than 1 % d0. However, the labeled compounds are not 100% of the deuterated form listed on our product insert. For example, upon analysis of 2-arachidonoyl glycerol-d8 it is expected to see masses associated with the d7, d6, d5 etc.

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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

This product is a DEA exempt preparation of a scheduled compound - no special processing required. For larger quantities or alternate sizes, please contact sales.

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