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ω-3 Arachidonic Acid

Cayman Chemical Item Number 90011

(CAS 24880-40-8)

ω-3 Arachidonic Acid (CAS 24880-40-8)

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Description

ω-3 Arachidonic acid is a rare PUFA found in trace amounts in dietary sources. ω-3 fatty acids are now known to be essential for infant growth and development and protect against heart disease, thrombosis, hypertension, and inflammatory and autoimmune disorders.1 In human platelet membranes, ω-3 arachidonic acid inhibits arachidonoyl-CoA synthetase with a Ki of 14 µM. It also inhibits arachidonoyl-CoA synthetase in calf brain extracts with an IC50 value of about 5 µM.2

1 Simopoulos, A.P. Omega-3 Fatty acids in health and disease and in growth and development. Am J Clin Nutr 54 438-463 (1991).

2 Neufeld, E.J., Sprecher, H., Evans, R.W., et al. Fatty acid structural requirements for activity of arachidonoyl-CoA synthetase. J Lipid Res 25 288-293 (1984).

Formal Name 8Z,​11Z,​14Z,​17Z-​eicosatetraenoic acid
CAS Number 24880-40-8
Molecular Formula C20H32O2
Formula Weight 304.5
Formulation A solution in ethanol
Purity >98%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CC/C=C\C/C=C\C/C=C\C/C=C\CCCCCCC(=O)​O

Background Reading

Neufeld, E.J., Sprecher, H., Evans, R.W., et al. Fatty acid structural requirements for activity of arachidonoyl-CoA synthetase. J Lipid Res 25 288-293 (1984).

Simopoulos, A.P. Omega-3 Fatty acids in health and disease and in growth and development. Am J Clin Nutr 54 438-463 (1991).

ω-3 Arachidonic Acid is available in the following screening library:

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Warning This product is not for human or veterinary use.

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