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Arachidonic Acid methyl esterCayman Chemical Item Number 90014 Methyl Arachidonate (CAS 2566-89-4) 
Arachidonic Acid methyl ester (CAS 2566-89-4)
Description
Arachidonic acid is the keystone essential fatty acid at the origin of the arachidonic acid cascade. It is converted by cyclooxygenase, lipoxygenase, and epoxygenase enzymes into more than one hundred fifty different potent primary autacoid metabolites in species ranging from fungi to plants to mammals. Arachidonic acid is stored in tissue phospholipids in esterified form, where it comprises a small but critically controlled percentage of the polyunsaturated fatty acid pool.1 Arachidonic acid content is frequently measured by the saponification of the lipid fraction followed by methyl esterification and gas chromatographic analysis of the resulting FAME (fatty acid methyl ester) compounds.2,3 Arachidonic acid methyl ester can also be incorporated into dietary regimens or fed to cultured cells as a source of exogenous arachidonate.
1 Holman, R.T. Control of polyunsaturated acids in tissue lipids. J Am Coll Cardiol 5 183-211 (1986).
2
Leichsenring, M., Sütterlin, N., Less, S., et al. Polyunsaturated fatty acids in erythrocyte and plasma lipids of children with severe protein- 3 Burdge, G.C., and Postle, A.D. Phospholipid molecular species composition of developing fetal guinea pig brain. Lipids 30 719-724 (1995).
Background ReadingLeichsenring, M., Sütterlin, N., Less, S., et al. Polyunsaturated fatty acids in erythrocyte and plasma lipids of children with severe protein- Burdge, G.C., and Postle, A.D. Phospholipid molecular species composition of developing fetal guinea pig brain. Lipids 30 719-724 (1995). Holman, R.T. Control of polyunsaturated acids in tissue lipids. J Am Coll Cardiol 5 183-211 (1986). Arachidonic Acid methyl ester is available in the following screening library: |
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Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins. |
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