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Arachidonoyl EthanolamideCayman Chemical Item Number 90050 Anandamide; AEA (CAS 94421-68-8) 
Arachidonoyl Ethanolamide (CAS 94421-68-8)
Description
Arachidonoyl ethanolamide (AEA) is the ethanolamine amide of arachidonic acid, first isolated from porcine brain.1 AEA is an endogenous cannabinoid neurotransmitter that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.2 AEA inhibits the specific binding of [3H]-
1 Devane, W.A., Hanus, L., Breuer, A., et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258 1946-1949 (1992).
2
Felder, C.C., Briley, E.M., Axelrod, J., et al. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-
Background ReadingDevane, W.A., Hanus, L., Breuer, A., et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258 1946-1949 (1992). Felder, C.C., Briley, E.M., Axelrod, J., et al. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor- Arachidonoyl Ethanolamide is available in the following screening library: |
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