Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Arachidonoyl Ethanolamide

Cayman Chemical Item Number 90050

Anandamide; AEA (CAS 94421-68-8)

Arachidonoyl Ethanolamide (CAS 94421-68-8)

See more	Fatty Acids (267) Inhibitors (493) Endocrinology (335) Neuroscience (654)

Description

Arachidonoyl ethanolamide (AEA) is the ethanolamine amide of arachidonic acid, first isolated from porcine brain.¹ AEA is an endogenous cannabinoid neurotransmitter that binds to both central cannabinoid (CB₁) and peripheral cannabinoid (CB₂) receptors.² AEA inhibits the specific binding of [³H]-HU-243 to synaptosomal membranes with a K_i value of 52 nM, compared to 46 nM for Δ⁹-THC.¹

1 Devane, W.A., Hanus, L., Breuer, A., et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258 1946-1949 (1992).

2 Felder, C.C., Briley, E.M., Axelrod, J., et al. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proc Natl Acad Sci USA 90 7656-7660 (1993).

Synonyms	Anandamide AEA
Formal Name	N-(2-hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
CAS Number	94421-68-8
Molecular Formula	C₂₂H₃₇NO₂
Formula Weight	347.5
Formulation	A solution in ethanol
Purity	≥98%
Stability	1 year
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCO

Background Reading

Devane, W.A., Hanus, L., Breuer, A., et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258 1946-1949 (1992).

Felder, C.C., Briley, E.M., Axelrod, J., et al. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proc Natl Acad Sci USA 90 7656-7660 (1993).

Arachidonoyl Ethanolamide is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
5 mg	$36.00		$0.00
10 mg	$68.00		$0.00
50 mg	$288.00		$0.00
100 mg	$504.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-11. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

1-Linoleoyl Glycerol

20-HETE Ethanolamide

2,3-dinor Thromboxane B₂ Lipid Maps MS Standard

(±)5(6)-EET Ethanolamide

(±)8(9)-EET Ethanolamide

AM1172

AMC Arachidonoyl Amide

Arachidonoyl 2'-Chloroethylamide

Arachidonoyl-2'-Fluoroethylamide

Arachidonoyl Cyclopropylamide

Arachidonoyl Ethanolamide-d₄

Arachidonoyl Ethanolamide-d₈

Arachidonoyl Ethanolamide Lipid Maps MS Standard

Arachidonoyl Ethanolamide Phosphate

Arachidonoyl-N,N-dimethyl amide

Arachidoyl Ethanolamide Exclusive

Cannabidiol (solution)

CAY10412 Exclusive

CB₂ Receptor Polyclonal Antibody

(±)-CP 47,497-C8-homolog Exclusive

(±)-CP 47,497-C8-homolog-d₇ (solution) Exclusive

(−)-CP 55,940

Docosanoyl Ethanolamide Exclusive

Eicosapentaenoyl Ethanolamide

Leukotriene B₄ Ethanolamide

Monoacylglycerol Lipase Polyclonal Antibody

N-Arachidonoyl-3-hydroxy-γ-Aminobutyric Acid

N-Arachidonoyl Dopamine

O-Arachidonoyl Glycidol Exclusive

Oleoyl Serotonin Exclusive

Oleoyl Serotonin-d₁₇ Exclusive

oxy-Arachidonoyl Ethanolamide

Palmitoleoyl Ethanolamide

PF-622

PF-750

Show all 35 Hide all but first 3

Downloads

	Download Product Insert 164 Kb PDF
	Download Material Safety Data Sheet (MSDS) 20 Kb PDF
	Printer-friendly version of this page small PDF (usually less than 100 Kb)
	• US Letter paper 8½″ × 11″
	• A4 paper 21cm × 29.7cm
	Chemical structure definitions are available for many Cayman products. See Chemical Structure Database for details.

Batch-specific Information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs	Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases	Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule	Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640