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Arachidonoyl m-Nitroaniline Exclusive

Cayman Chemical Item Number 90059

AmNA

Arachidonoyl m-Nitroaniline

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Description

Arachidonoyl m-Nitroaniline (AmNA) is one of several nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity.¹ FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its nominal endogenous substrate anandamide (arachidonyl ethanolamide; AEA). It also will hydrolyze fatty acid amides with fewer carbons and fewer double bonds than arachidonate (see also Decanoyl m-Nitroaniline; Catalog No. 90349). Exposure of AmNA to FAAH activity results in the release of the yellow colorimetric dye m-nitroaniline (ε = 13,500 at 410 nm). This offers the potential for fast and convenient measurements of FAAH activity using a 96 well plate spectrophotometer.

1 Patricelli, M.P., and Cravatt, B.F. Characterization and manipulation of the acyl chain selectivity of fatty acid amide hydrolase. Biochemistry 40 6107-6115 (2001).

Synonyms	AmNA
Formal Name	N-(3-nitrophenyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
Molecular Formula	C₂₆H₃₆N₂O₃
Formula Weight	424.6
Formulation	A solution in methyl acetate
Purity	>98%
λ_max	203, 242 nm
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)Nc1cccc(c1)[N](=O)O

Background Reading

Patricelli, M.P., and Cravatt, B.F. Characterization and manipulation of the acyl chain selectivity of fatty acid amide hydrolase. Biochemistry 40 6107-6115 (2001).

Arachidonoyl m-Nitroaniline is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
5 mg	$38.00		$0.00
10 mg	$72.00		$0.00
25 mg	$171.00		$0.00
50 mg	$304.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-11. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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N-Decanoyl p-Nitroaniline

Oleyl Trifluoromethyl Ketone

Thioarginine (hydrobromide)

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Batch-specific Information

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