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N-Arachidonoyl-γ-Aminobutyric Acid

Cayman Chemical Item Number 90067

NAGABA (CAS 128201-89-8)

N-Arachidonoyl-γ-Aminobutyric Acid (CAS 128201-89-8)

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Description

Several different arachidonoyl amino acids, including N-Arachidonoyl-γ-aminobutyric acid (NAGABA), have been isolated and characterized from bovine brain.The glycine congener (NAGly) was further characterized and found to suppress formalin-induced pain in rats. NAGABA was also found to suppress normal responses to pain, but has not been fully characterized to date.1

1 Huang, S.M., Bisogno, T., Petros, T.J., et al. Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain. J Biol Chem 276(46) 42639-42644 (2001).

Synonyms
  • NAGABA
Formal Name 4-​[(1-​oxo-​5Z,​8Z,​11Z,​14Z-​eicosatetraenyl)amino]-​butanoic acid
CAS Number 128201-89-8
Molecular Formula C24H39NO3
Formula Weight 389.6
Formulation A solution in ethanol
Purity >98%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
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CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)​NCCCC(=O)​O

Background Reading

Huang, S.M., Bisogno, T., Petros, T.J., et al. Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain. J Biol Chem 276(46) 42639-42644 (2001).

N-Arachidonoyl-γ-Aminobutyric Acid is available in the following screening libraries:

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