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HU-210

Cayman Chemical Item Number 90082

(CAS 112830-95-2)

HU-210 (CAS 112830-95-2)

See more	Cannabinoids (333) Endocrinology (337) Forensic Science (369) Neuroscience (725)

Description

HU-210 is a synthetic agonist analog of Δ⁹-THC, which is the primary psychoactive component of marijuana. HU-210 is a potent central cannabinoid (CB₁) and peripheral cannabinoid (CB₂) receptor agonist. It binds to neuroblastoma cell membrane CB₁ receptors with about the same affinity as CP-55940.¹ In mouse behavior models (hypothermia, analgesia, hypoactivity, and catalepsy) the ED₅₀ is 5-20 µg/kg.²

1 Slipetz, D.M., O'Neill, G.P., Gavreau, L., et al. Activation of the human peripheral cannabinoid receptor results in inhibition of adenylyl cyclase. Mol Pharmacol 48 352-361 (1995).

2 Howlett, A.C., Berglund, B., and Melvin, L.S. Cannabinoid receptor agonists and antagonists. Curr Pharm Des 1 343-354 (1995).

Formal Name	3-(1,1'-dimethylheptyl)-6aR,7,10,10aR-tetrahydro-1-hydroxy-6,6-dimethyl-6H-dibenzo[b,d]pyran-9-methanol
CAS Number	112830-95-2
Molecular Formula	C₂₅H₃₈O₃
Formula Weight	386.6
Formulation	A crystalline solid
Purity	>98%
λ_max	207 nm
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(CO)CC21

Background Reading

Slipetz, D.M., O'Neill, G.P., Gavreau, L., et al. Activation of the human peripheral cannabinoid receptor results in inhibition of adenylyl cyclase. Mol Pharmacol 48 352-361 (1995).

Howlett, A.C., Berglund, B., and Melvin, L.S. Cannabinoid receptor agonists and antagonists. Curr Pharm Des 1 343-354 (1995).

HU-210 is available in the following screening library:

Cannabinoid Agonist Screening Library (96-Well)

Size	Global Purchasing
1 mg	See a distributor in your region for pricing
5 mg	See a distributor in your region for pricing
10 mg	See a distributor in your region for pricing
25 mg	See a distributor in your region for pricing

To ask for assistance with one of our products please contact a Technical Support Scientist.

This product requires special processing and/or additional information before it can be shipped. A Customer Service representative will contact you within 24 hours of receipt of your order.

Warning This product is not for human or veterinary use.

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(±)-CP 47,497-C8-homolog Exclusive A potent bicyclic CB analog	33.614779595787
(±)-CP 47,497-C8-homolog (solution) Exclusive A potent bicyclic CB analog	43.928671821398
HU-210 (solution) A potent synthetic cannabinoid	30.987411207576
Cannabidiol A neuroprotective phenolic compound from marijuana	31.817340173638
Cannabidiol (solution) A neuroprotective phenolic compound from marijuana	45.111998995479
Synthetic Cannabinoid HPLC Mixture II Contains a selection of the most common JWH-, CP-, and HU-series CB receptor agonists	44.388457144890

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