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Eicosapentaenoic Acid

Cayman Chemical Item Number 90110

Timnodonic Acid; EPA (CAS 10417-94-4)

Eicosapentaenoic Acid (CAS 10417-94-4)

See more	Fatty Acids (272)

Description

EPA is an ω-3 fatty acid abundantly available in marine organisms. It is oxygenated by COX-1 and COX-2 at rates of about 5% and 30%, respectively, compared to arachidonic acid.¹ EPA has been shown to offer protection against coronary heart disease, thrombosis, ischemic brain injury, scaly dermatitis, and some inflammatory diseases.^2,3

1 Wada, M., DeLong, C.J., Hong, Y.H., et al. Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products. J Biol Chem 282(31) 22254-22266 (2007).

2 Yerram, N.R., Moore, S.A., and Spector, A.A. Eicosapentaenoic acid metabolism in brain microvessel endothelium: Effect on prostaglandin formation. J Lipid Res 30 1747-1757 (1989).

3 Takeuchi, H., Inoue, J., Yoshida, M., et al. Dietary effects of n-3 eicosapentaenoic acid on essential fatty acid-deficiency symptoms of rats. Agric Biol Chem 53 3225-3232 (1989).

Synonyms	Timnodonic Acid EPA
Formal Name	5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid
CAS Number	10417-94-4
Molecular Formula	C₂₀H₃₀O₂
Formula Weight	302.5
Formulation	A solution in ethanol
Purity	≥98%
Stability	1 year
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O

Background Reading

Yerram, N.R., Moore, S.A., and Spector, A.A. Eicosapentaenoic acid metabolism in brain microvessel endothelium: Effect on prostaglandin formation. J Lipid Res 30 1747-1757 (1989).

Wada, M., DeLong, C.J., Hong, Y.H., et al. Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products. J Biol Chem 282(31) 22254-22266 (2007).

Takeuchi, H., Inoue, J., Yoshida, M., et al. Dietary effects of n-3 eicosapentaenoic acid on essential fatty acid-deficiency symptoms of rats. Agric Biol Chem 53 3225-3232 (1989).

Eicosapentaenoic Acid is available in the following screening libraries:

Size	Global Purchasing
50 mg	See a distributor in your region for pricing
100 mg	See a distributor in your region for pricing
250 mg	See a distributor in your region for pricing
500 mg	See a distributor in your region for pricing

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

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