See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!

Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…
Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.

9(Z),11(E)-Conjugated Linoleic Acid

Cayman Chemical Item Number 90140

Bovinic acid; 9Z,11E-CLA (CAS 2540-56-9)

9(Z),11(E)-Conjugated Linoleic Acid (CAS 2540-56-9)

See more

Description

Conjugated linoleic acid (CLA) refers to a family of 8 geometric isomers of linoleic acid in which the two double bonds are contiguous. (The predominant form of linoleic acid in nature, 18:ω6, has double bonds at 9 and 12, interrupted by a methylene carbon.) CLA is found in both meat and dairy products, but it is not found to any significant degree in plants. The predominant isomer of CLA in animal tissue is 9Z,11E; smaller amounts of 10E,12Z also occur. Various antioxidant and antitumor activities have been attributed to CLA or its downstream metabolites.1 Reported health benefits of dietary supplementation with CLA have been attributed variously to competitive inhibition of Δ6-desaturase and/or PPARγ activation.2

1 Shultz, T.D., Chew, B.P., Seaman, W.R., et al. Inhibitory effect of conjugated dienoic derivatives of linoleic acid and β-carotene on the in vitro growth of human cancer cells. Cancer Lett 63 125-133 (1992).

2 Houseknecht, K.L., Vanden Heuvel, J.P., Moya-Camarena, S.Y., et al. Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat.. Biochem Biophys Res Commun 244 678-682 (1998).

Synonyms
  • Bovinic acid
  • 9Z,11E-CLA
Formal Name 9Z,​11E-​octadecadienoic acid
CAS Number 2540-56-9
Molecular Formula C18H32O2
Formula Weight 280.5
Formulation A solution in ethanol
Purity ≥98%
λmax 233 nm
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES
Copy SMILES to clipboard
CCCCCC/C=C/C=C\CCCCCCCC(O)​=O

Background Reading

Shultz, T.D., Chew, B.P., Seaman, W.R., et al. Inhibitory effect of conjugated dienoic derivatives of linoleic acid and β-carotene on the in vitro growth of human cancer cells. Cancer Lett 63 125-133 (1992).

Houseknecht, K.L., Vanden Heuvel, J.P., Moya-Camarena, S.Y., et al. Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat.. Biochem Biophys Res Commun 244 678-682 (1998).

9(Z),11(E)-Conjugated Linoleic Acid is available in the following screening libraries:

Size Global Purchasing
10 mg See a distributor in your region for pricing
50 mg See a distributor in your region for pricing
100 mg See a distributor in your region for pricing
500 mg See a distributor in your region for pricing

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

10(E),12(Z)-Conjugated Linoleic Acid
9(E),11(E)-Conjugated Linoleic Acid
Linoleic Acid
Linoleic Acid (peroxide free)
Show all 4 Hide all but first 3

Downloads

Batch-specific Information

Login to access batch-specific information

Cayman Chemical is a manufacturer, supplier and vendor of biochemical reagents, assay kits, antibodies, and proteins.

Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

Lost password?