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Linoleic Acid

Cayman Chemical Item Number 90150

Telfairic Acid (CAS 60-33-3)

Linoleic Acid (CAS 60-33-3)

See more	Fatty Acids (267)

Description

Linoleic acid is an essential fatty acid and one of the most abundant PUFAs in the western diet. Deficiencies in linoleic acid are linked to defective wound healing, growth retardation, and dermatitis.^1,2 Linoleic acid is metabolized by 15-LO in both plants and animals to form 9- and 13-HODE.³

1 Soyland, E., Fund, J., Rajka, G., et al. Effect of dietary supplementation with very-long-chain n-3 fatty acids in patients with psoriasis. N Engl J Med 328 1812-1816 (1993).

2 Hashimoto, A., Katagiri, M., Torii, S., et al. Effect of the dietary α-linolenate/linoleate balance on leukotriene production and histamine release in rats. Prostaglandins 36 3-15 (1988).

3 Vick, B.A. Oxygenated fatty acids of the lipoxygenase pathway. 167-191 (1993).

Synonyms	Telfairic Acid
Formal Name	9Z,12Z-octadecadienoic acid
CAS Number	60-33-3
Molecular Formula	C₁₈H₃₂O₂
Formula Weight	280.5
Formulation	A solution in ethanol
Purity	>98%
Stability	2 years
Storage	-20°C
Shipping	Wet ice in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCC/C=C\C/C=C\CCCCCCCC(=O)O

Background Reading

Srivastava, K.C., and Awasthi, K.K. A comparative study on the effect of cis (oleic, linoleic) and trans (elaidic, linoelaidic) fatty acids on the in vitro prostaglandin biosynthesis in human blood platelets from (1-¹⁴C) arachidonic acid. Prostaglandins Leukot Med 9 669-684 (1982).

Rose, D.P., Connolly, J.M., and Liu, X. Effects of linoleic acid on the growth and metastasis of two human breast cancer cell lines in nude mice and the inverse capacity of these cell lines in vitro. Cancer Res 54 6557-6562 (1994).

Hashimoto, A., Katagiri, M., Torii, S., et al. Effect of the dietary α-linolenate/linoleate balance on leukotriene production and histamine release in rats. Prostaglandins 36 3-15 (1988).

Oliver, M.F. Linoleic acid, antioxidants, and coronary heart disease. Biochem Soc Trans 18 1049-1051 (1990).

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Linoleic Acid is available in the following screening library:

Fatty Acid Screening Library (96-Well)

Size	Price	Quantity	Subtotal
50 mg	$15.00		$0.00
100 mg	$20.00		$0.00
500 mg	$25.00		$0.00
1 g	$30.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-12. Prices are subject to change without notice.

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