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5(Z),8(Z),11(Z)-Eicosatrienoic Acid Ethanolamide

Cayman Chemical Item Number 90195

Mead Acid Ethanolamide (CAS 169232-04-6)

5(Z),8(Z),11(Z)-Eicosatrienoic Acid Ethanolamide (CAS 169232-04-6)

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Description

5(Z),8(Z),11(Z)-Eicosatrienoic acid ethanolamide is essentially identical to AEA in its agonist binding to CB1 and CB2 receptors. In L cells expressing the human CB1 receptor, the Ki value for 5(Z),8(Z),11(Z)-eicosatrienoic acid ethanolamide and AEA binding is 753 nM. In AtT-20 cells expressing the human CB2 receptor, 5(Z),8(Z),11(Z)-eicosatrienoic acid ethanolamide and AEA bind with a Ki value of 1,810 nM.1

1 Priller, J., Briley, E.M., Mansouri, J., et al. Mead ethanolamide, a novel eicosanoid, is an agonist for the central (CB1) and peripheral (CB2) cannabinoid receptors. Mol Pharmacol 48 288-292 (1995).

Synonyms
  • Mead Acid Ethanolamide
Formal Name N-​(2-​hydroxyethyl)-​5Z,​8Z,​11Z-​eicosatrienamide
CAS Number 169232-04-6
Molecular Formula C22H39NO2
Formula Weight 349.6
Formulation A solution in ethanol
Purity ≥98%
Stability 1 year
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES
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CCCCCCCC/C=C\C/C=C\C/C=C\CCCC(=O)​NCCO

Background Reading

Priller, J., Briley, E.M., Mansouri, J., et al. Mead ethanolamide, a novel eicosanoid, is an agonist for the central (CB1) and peripheral (CB2) cannabinoid receptors. Mol Pharmacol 48 288-292 (1995).

5(Z),8(Z),11(Z)-Eicosatrienoic Acid Ethanolamide is available in the following screening library:

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5 mg See a distributor in your region for pricing
10 mg See a distributor in your region for pricing

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