Elaidic acid is the 9-trans isomer of oleic acid. It is a monounsaturated trans-fatty acid which can be found in partially hydrogenated cooking oils. In human platelets incubated with arachidonic acid, elaidic acid inhibits HHT and HETE formation while inducing prostaglandin and thromboxane synthesis.1
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Srivastava, K.C., and Awasthi, K.K. A comparative study on the effect of cis (oleic, linoleic) and trans (elaidic, linoelaidic) fatty acids on the in vitro prostaglandin biosynthesis in human blood platelets from (1-14C) arachidonic acid. Prostaglandins Leukot Med 9 669-684 (1982).
Srivastava, K.C., and Awasthi, K.K. A comparative study on the effect of cis (oleic, linoleic) and trans (elaidic, linoelaidic) fatty acids on the in vitro prostaglandin biosynthesis in human blood platelets from (1-14C) arachidonic acid. Prostaglandins Leukot Med 9 669-684 (1982).
Moore, C.E., and Dhopeshwarkar, G.A. Positional specificity of trans fatty acids in fetal lecithin. Lipids 16 479-484 (1981).
Moore, C.E., and Dhopeshwarkar, G.A. Placental transport of trans fatty acids in the rat. Lipids 15 1023-1028 (1980).
Naccache, P.H., Moiski, T.F.P., Volpi, M., et al. Modulation of rabbit neutrophil aggregation and degranulation by free fatty acids. J Leukoc Biol 36 333-340 (1984).
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