MEDICA 16 is a β,β'-dimethyl hexadecanedioic acid which exhibits hypolipidemic and antidiabetogenic effects in the rat. In animals that were fed a diet which was 0.25% MEDICA 16 by weight, the hypolipidemic effect consisted of a 70-80% decrease in plasma chylomicrons and VLDL-triacylglycerols as well as a 40-60% decrease in plasma VLDL-cholestrol.1
1
Hertz, B.K., and Bar-Tana, J. Tissue selective modulation of redox and phosphate potentials by β,β'-methyl-substituted hexadecanedioic acid. Endocrinology1311629-1635(1992).
Formal Name
3,3,14,14-tetramethylhexadecanedioic acid
CAS Number
87272-20-6
Molecular Formula
C20H38O4
Formula Weight
342.5
Formulation
A crystalline solid
Purity
>98%
Stability
1 year
Storage
-20°C
Shipping
Room temperature
in continental US; may vary elsewhere
SMILES
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OC(=O)CC(C)(C)CCCCCCCCCCC(C)(C)CC(=O)O
Background Reading
Hertz, B.K., and Bar-Tana, J. Tissue selective modulation of redox and phosphate potentials by β,β'-methyl-substituted hexadecanedioic acid. Endocrinology1311629-1635(1992).
MEDICA 16 is available in the following screening
libraries: