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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

4,5-dehydro Docosahexaenoic Acid

Cayman Chemical Item Number 90312

4,5-dehydro Cervonic Acid; 4,5-dehydro DHA

4,5-dehydro Docosahexaenoic Acid

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Description

Docosahexaenoic acid (DHA; 22:6ω3) is one of the essential dietary ω-3 unsaturated fatty acids and the preferred n-3 fatty acid for development of the brain and retina.1 4,5-dehydro DHA is a novel analog of DHA in which the double bond closest to the carboxyl group has been converted into an acetylene. 4,5-dehydro DHA is a novel compound that has not been studied in biological systems. However, the corresponding acetylene in the C-20 fatty acid series (5,6-dehydro arachidonic acid) is a well known inhibitor of 5-lipoxygenase.2

1 Anderson, G.J., Connor, W.E., and Corliss, J.D. Docosahexaenoic acid is the preferred dietary n-3 fatty acid for the development of the brain and retina. Pediatr Res 27 89-97 (1990).

2 Sok, D., Han, C., Pai, J., et al. Inhibition of leukotriene biosynthesis by acetylenic analogs. Biochem Biophys Res Commun 107 101-108 (1982).

Synonyms
  • 4,5-dehydro Cervonic Acid
  • 4,5-dehydro DHA
Formal Name 7Z,​10Z,​13Z,​16Z,​19Z-​docosapentaen-​4-​ynoic acid
Molecular Formula C22H30O2
Formula Weight 326.5
Formulation A solution in ethanol
Purity ≥98%
Stability 1 year
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
SMILES
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CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(=O)​O

Background Reading

Anderson, G.J., Connor, W.E., and Corliss, J.D. Docosahexaenoic acid is the preferred dietary n-3 fatty acid for the development of the brain and retina. Pediatr Res 27 89-97 (1990).

Sok, D., Han, C., Pai, J., et al. Inhibition of leukotriene biosynthesis by acetylenic analogs. Biochem Biophys Res Commun 107 101-108 (1982).

4,5-dehydro Docosahexaenoic Acid is available in the following screening library:

Size Price Quantity Subtotal
25 µg $71.00 $0.00
50 µg $135.00 $0.00
100 µg $256.00 $0.00
500 µg $1,136.00 $0.00
Bulk Contact
Cart Total $0.00

This product is available in custom sizes and/or larger quantities.

Please contact our Sales Department for a quote or to purchase.

Pricing updated 2012-02-12. Prices are subject to change without notice.

To ask for assistance with one of our products please contact a Technical Support Scientist.

Warning This product is not for human or veterinary use.

Related Products

5,6-dehydro Arachidonic Acid
Docosahexaenoic Acid
Docosahexaenoic Acid methyl ester

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