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Decanoyl m-Nitroaniline Exclusive

Cayman Chemical Item Number 90349

DemNA (CAS 72298-61-4)

Decanoyl m-Nitroaniline (CAS 72298-61-4)

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Description

Decanoyl m-Nitroaniline (DemNA) is one of several nitroaniline fatty acid amides which can be used to measure fatty acid amide hydrolase (FAAH) activity.¹ FAAH is a relatively unselective enzyme in that it accepts a variety of amide head groups other than the ethanolamine of its endogenous substrate anandamide (arachidonyl ethanolamide; AEA). It also will hydrolyze fatty acid amides with fewer carbons and fewer double bonds than arachidonate. Exposure of DemNA to FAAH activity results in the release of the yellow colorimetric dye m-nitroaniline (ε = 13,500 at 410 nm) This allows the fast and convenient measurement of FAAH activity using a 96 well plate spectrophotometer.

1 Patricelli, M.P., and Cravatt, B.F. Characterization and manipulation of the acyl chain selectivity of fatty acid amide hydrolase. Biochemistry 40 6107-6115 (2001).

Synonyms	DemNA
Formal Name	N-(3-nitrophenyl)-decanamide
CAS Number	72298-61-4
Molecular Formula	C₁₆H₂₄N₂O₃
Formula Weight	292.4
Formulation	A crystalline solid
Purity	≥98%
λ_max	202, 241 nm
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCCCCCC(=O)Nc1ccc(cc1)[N](=O)O

Background Reading

Patricelli, M.P., and Cravatt, B.F. Characterization and manipulation of the acyl chain selectivity of fatty acid amide hydrolase. Biochemistry 40 6107-6115 (2001).

Size	Price	Quantity	Subtotal
5 mg	$41.00		$0.00
10 mg	$78.00		$0.00
25 mg	$185.00		$0.00
50 mg	$328.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-05-26. Prices are subject to change without notice.

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