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Palmitoyl Ethanolamide

Cayman Chemical Item Number 90350

Palmidrol; PEA (CAS 544-31-0)

Palmitoyl Ethanolamide (CAS 544-31-0)

See more	Endocannabinoids (54) Fatty Acids (267) Neuroscience (654)

Description

Palmitoyl ethanolamide (PEA) is an endogenous cannabinoid found in brain, liver, and other mammalian tissues.¹ PEA has also been isolated from egg yolk, and found to have anti-anaphylactic and anti-inflammatory activity in vitro.² PEA is an endocannabinoid which has been shown to significantly elevate cAMP in cells expressing CB₂ receptors. However, its affinity for CB₂ receptors is relatively low, at about 10 µM. CB₁ receptors have no appreciable affinity for PEA.³

1 Bachur, N.R., Masek, K., Melmon, K.L., et al. Fatty acid amides of ethanolamine in mammalian tissues. J Biol Chem 240 1019-1024 (1965).

2 Ganley, O.H., Graessle, O.E., Robinson, H.J., et al. Anti-inflammatory activity of compounds obtained from egg yolk, peanut oil, and soybean lecithin. J Lab Clin Med 51 709-714 (1958).

3 Devane, W.A., Hanus, L., Breuer, A., et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258 1946-1949 (1992).

Synonyms	Palmidrol PEA
Formal Name	N-(2-hydroxyethyl)-hexadecanamide
CAS Number	544-31-0
Molecular Formula	C₁₈H₃₇NO₂
Formula Weight	299.5
Formulation	A crystalline solid
Purity	≥98%
Stability	2 years
Storage	-20°C
Shipping	Room temperature in continental US; may vary elsewhere
SMILES	Copy SMILES to clipboard CCCCCCCCCCCCCCCC(=O)NCCO

Background Reading

Devane, W.A., Hanus, L., Breuer, A., et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258 1946-1949 (1992).

Palmitoyl Ethanolamide is available in the following screening library:

Bio-active Lipid I Screening Library (96-Well)

Size	Price	Quantity	Subtotal
5 mg	$19.00		$0.00
10 mg	$36.00		$0.00
50 mg	$152.00		$0.00
100 mg	$266.00		$0.00
Bulk	Contact
		Cart Total	$0.00

Pricing updated 2012-02-11. Prices are subject to change without notice.

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