Proteins

Eicosanoid Metabolism

Item Number	Product	CAS	Plain Text Name	Synonyms	Keywords
10341	12-Lipoxygenase (platelet-type, mouse recombinant) Active, pure human recombinant enzyme Source: active recombinant N-terminal His-tagged protein, expressed using the baculovirus system · M_r: 76.4 kDa ·		12-lipoxygenase-platelet-type-mouse-recombinant	12-LOX; 12-LO	12 LOs 12 LOXs 12 lipoxygenase P 12LO ALOX arachidonic acids platelet-type leukocyte-type epidermal-type 12-HETE 12 HETE 12-HpETE 12 HpETE 15-HETE 15 HETE 15-HpETE 15 HpETE active
10007950	15-hydroxy Prostaglandin Dehydrogenase (human recombinant) Active, pure human recombinant enzyme Source: active human recombinant N-terminal GST-tagged protein expressed in E. coli · M_r: ~55 kDa ·		15-hydroxy-prostaglandin-dehydrogenase-human-recombinant	15-hydroxy PGDH	15-OH PGDH 15-PGDH proteins binding enzymes dehydrogenases recombinant tumors suppressors colon thyroid breast cells active
60712	15-Lipoxygenase (soybean P₁) Active enzyme M_r: 94.00 · Specific activity: >100,000 units/mg · Enzyme Commission (EC): 1.13.11.33 ·		15-lipoxygenase-soybean-p1	15-LO; 15-LOX	15-LOs soybean 15-lipoxygenases P1 enzymes active
60700	15-Lipoxygenase (soybean P₁) - Purified Active, pure recombinant enzyme M_r: 94 kDa · Specific activity: >1 million units/mg · Enzyme Commission (EC): 1.13.11.33 ·		15-lipoxygenase-soybean-p1-purified	15-LO; 15-LOX	15-LOs enzymes soybean 15-lipoxygenases P1 active
60402	5-Lipoxygenase (human recombinant) Active, human recombinant enzyme Source: active recombinant enzyme expressed in Sf21 cells · M_r: 78 kDa · Enzyme Commission (EC): 1.13.11.34 ·		5-lipoxygenase-human-recombinant	5-LO; 5-LOX	5-LOs enzymes 5-lipoxygenases atherosclerosis active
60400	5-Lipoxygenase (potato) Active enzyme M_r: 85.00 · Specific activity: >12,000 units/mg · Enzyme Commission (EC): 1.13.11.34 ·		5-lipoxygenase-potato	Potato Lipoxygenase; 5-LO; 5-LOX	5-LOs enzymes potato 5-lipoxygenases active
10803	Autotaxin (human recombinant) Active, pure human recombinant enzyme Source: active recombinant C-terminal histidine-tagged protein expressed using a baculovirus overexpression system in Sf21 cells · M_r: 98.8 kDa ·		autotaxin-human-recombinant	Ectonucleotide Pyrophosphatase/Phosphodiesterase-2; Lysophospholipase D; ENPP-2	lipids hydrolysis lysophophatidyl choline lysophophatidic acids secreated glycosylated active
60100	COX-1 (ovine) Active, pure human recombinant enzyme M_r: 70 kDa · Specific activity: >40,000 units/mg · Enzyme Commission (EC): 1.14.99.1 ·		cox-1-ovine	Prostaglandin H Synthase 1; Prostaglandin Endoperoxide Synthase; Cyclooxygenase 1	cyclooxygenases COX-1 enzymes PGHS1 PGHS-1 constitutive prostaglandins synthases 1 sheep 760110 tween 20 active
360100	COX-1 (ovine) Electrophoresis Standard M_r: 70.00 ·		cox-1-ovine-electrophoresis-standard	Prostaglandin H Synthase 1; Cyclooxygenase 1; PGHS-1	PGHS-1 sheep COX1 Western blots immunoblotting cyclooxygenases pghs1 synthases standards prostaglandins antibodies
60122	COX-2 (human recombinant) Active, pure human recombinant enzyme Source: active recombinant N-terminal His-tagged enzyme isolated from a Baculovirus overexpression system in Sf21 cells · M_r: 70.00 · Specific activity: >8,000 units/mg ·		cox-2-human-recombinant	Prostaglandin H Synthase 2; Cyclooxygenase 2	cyclooxygenases COX2 PGHS-2 PGHS2 inducible synthases synthase-2 prostaglandins enzymes active
60120	COX-2 (ovine) Active, pure human recombinant enzyme M_r: 72.00 · Specific activity: >3,000 units/mg · Enzyme Commission (EC): 1.14.99.1 ·		cox-2-ovine	Prostaglandin H Synthase 2; Inducible cyclooxygenase (ovine); Cyclooxygenase 2	cyclooxygenases COX2 PGHS-2 PGHS2 inducible sheep synthases synthase-2 enzymes 760112 active
360120	COX-2 (ovine) Electrophoresis Standard M_r: 72.00 ·		cox-2-ovine-electrophoresis-standard	Prostaglandin H Synthase 2; Cyclooxygenase 2; PGHS-2	standards prostaglandins PGHS-2 sheep COX2 pghs2 synthases western blots immunoblotting cyclooxygenases antibodies
10007817	Leukotriene A₄ Hydrolase (human recombinant) Active, pure human recombinant enzyme Source: active recombinant C-terminal His-tagged enzyme expressed in E. coli · M_r: ~69 kDa ·		leukotriene-a4-hydrolase-human-recombinant	LTA4H	leukotrienes bifunctional zinc metalloenzymes converts LTB4 neutrophils chemoattractants hydrolases activity anion-dependent aminopeptidases drugs leukocytes infiltration inflammation E. coli epoxides atherosclerosis active
10279	PAF Acetylhydrolase (human recombinant) Active, pure human recombinant enzyme Source: active recombinant N-terminal His-tagged protein purified from E. coli · M_r: 46.4 kDa ·		paf-acetylhydrolase-human-recombinant	Lp-PLA2; PAF-AH; Platelet-Activating Factor Acetylhydrolase; Lipoprotein PLA2	proteins PAFs lipids mediator inflammation PAFAH enzymes PAF AH phospholipases PLA2s inflammatory N-terminal His-tags His-tagged active
10006593	Prostaglandin D Synthase (hematopoietic-type; human recombinant) Active, pure human recombinant enzyme Source: active human recombinant N-terminal His-tagged protein; purified from an E. coli overexpression system · M_r: 24.3 kDa · One unit of enzyme produces one µmole of PGD₂/min at 25°C in 100 mM Tris-HCl buffer, pH 8.0, containing 1 mM GSH, 1 mg/ml magnesium chloride, and 40 µM PGH₂		prostaglandin-d-synthase-hematopoietic-type-human-recombinant	Hematopoietic-PGDS; H-PGDS; PGD Synthase (hematopoietic-type; human recombinant)	prostaglandins synthases PGDs PGD2 HPGDS H-PGDS enzymes peripheral tissues antigen-presenting cells mast megakaryocytes glutathiones glutathione-S-transferases allergen allergy allergic mediators active
10004347	Prostaglandin D Synthase (hematopoietic-type; mouse recombinant) Excl. For immunochemical detection of H-PGDS Source: active mouse recombinant enzyme purified from E. coli overexpression system · M_r: 23.5 kDa ·		prostaglandin-d-synthase-hematopoietic-type-mouse-recombinant	Hematopoietic-PGDS; H-PGDS	PGH2 lipocalin-type .beta.-trace prostaglandins hematopoietic enzymes PGD2 proteins recombinant inflammation activity high throughput screening inhibitors inhibits inhibition assays HPGDS H-PGDS active
10006788	Prostaglandin D Synthase (lipocalin-type; human recombinant) A highly purified, active enzyme preparation Source: active recombinant enzyme expressed in E. coli · M_r: 46 kDa · Specific activity: 2.2 units/mg · Protein concentration: 0.5 mg/ml · One unit of enzyme produces one µmole of prostaglandin D₂ (PGD₂)/min at 25°C in 100 mM Tris-HCl buffer, pH 8.0, containing 1 mM GSH, 1 mg/ml γ-globulin, and 40 µM PGH₂		prostaglandin-d-synthase-lipocalin-type-human-recombinant	L-PGDS; Lipocalin-PGDS	prostaglandins synthases PGDs PGD2 H-PGDS enzymes peripheral tissues antigen-presenting cells mast megakaryocytes glutathiones glutathione-S-transferases allergen allergy allergic mediators neurochemistry lpgds l-pgds active
10006787	Prostaglandin D Synthase (lipocalin-type; mouse recombinant) Highly purified, active enzyme preparation Source: active recombinant GST-tagged enzyme expressed in E. coli · M_r: 46 kDa · One unit of enzyme produces one µmole of prostaglandin D₂ (PGD₂)/min at 25°C in 100 mM Tris-HCl buffer, pH 8.0, containing 1 mM GSH, 1 mg/ml γ-globulin, and 40 µM PGH₂		prostaglandin-d-synthase-lipocalin-type-mouse-recombinant	L-PGDS; Lipocalin-PGDS	prostaglandins synthases PGDs PGD2 H-PGDS enzymes peripheral tissues antigen-presenting cells mast megakaryocytes glutathiones glutathione-S-transferases allergen allergy allergic mediators neurochemistry lpgds l-pgds active
10010548	Prostaglandin D Synthase (lipocalin-type; rat recombinant) Excl. Active L-PGDS Source: active recombinant N-terminal GST-tagged protein purified from E. coli · M_r: 47.5 kDa ·		prostaglandin-d-synthase-lipocalin-type-rat-recombinant	L-PGDS; Lipocalin-PGDS	prostaglandins PGH2 beta-trace b-trace proteins assays neurochemistry rL-PGDS rlPGDS .beta.-trace beta-trace b-trace recombinant human cerebrospinal fluid PGs CSF GST-tags GST-tagged N-terminal lpgds l-pgds active
10007939	Prostaglandin E Synthase-1 (microsomal) (human recombinant) An anti-inflammatory drug target Source: active recombinant enzyme isolated from a baculovirus overexpression system in Sf21 cells · M_r: ~21 kDa ·		prostaglandin-e-synthase-1-microsomal-human-recombinant	Membrane-Associated PGES-1; Prostaglandin H/E Isomerase; PIG12; mPGE Synthase-1; MGST1-L1	enzymes proteins PGs prostaglandins catalyzes conversion PGH2 PGE2 membrane-associated eicosanoids glutathiones metabolisms MAPEG expression proinflammatory stimuli stimulus IL-1.beta. IL-1b interleukins glucocorticoids synovial tissues primary synoviocytes rheumatiod arthritis fever onset drugs anti-inflammatory therapy therapies E. coli mPGES mPGES-1 mPGES1 active PTGES
10010498	Prostaglandin E Synthase (cytosolic) (human recombinant, inactive protein) Inactive cPGES		prostaglandin-e-synthase-cytosolic-human-recombinant-inactive-protein	Hsp90 Co-chaperone; p23; Telomerase-binding protein p23; cPGE Synthanse; cPGES	cPGES cPGE synthases telomerase-binding proteins p23 Hsp90 cochaperone PGES cytosolic enzymes PTGES
10007940	Prostaglandin F Synthase (human recombinant) Active, pure human recombinant enzyme Source: active recombinant C-terminal His-tagged protein expressed in E. coli · M_r: ~37 kDa · Protein concentration: 0.8 mg/ml ·		prostaglandin-f-synthase-human-recombinant	AKR1C3; PGFS	11.beta.-PGF2.alpha. 11b-PGF2alpha 9,11-endoperoxides 11-ketoreductases aldo-keto reductases human monomeric proteins catalyzing catalyzes isomerization PGH2 PGD2 NADPH nicotinamide adenine dinucleotide phosphates enzymes carbonyls nitroacetophenones nitrobenzaldehydes 9,10-phenanthrene quinine PQ E. coli gel electrophoresis commassie staining active
10009563	sPLA₂ (human recombinant Type V) Active, pure human recombinant enzyme Source: active human recombinant protein expressed in E. coli · M_r: 14 kDa ·		spla2-human-recombinant-type-v	Secretory Phospholipase A2 (Group V); gVPLA2	proteins binding enzymes secretory phospholipases recombinant E. coli catalyzes hydrolysis fatty acids sn-2 glycerophospholipids isoforms arachidonic mobilization macrophages mast cells golgi apparatus nuclear envelope plasma membranes murine bone marrow-derived rat mouse heart lung placenta spleen P388D1 electrophoresis coomassie staining active
60500	sPLA₂ (Type III) Active, partially purified enzyme M_r: 14 kDa · Enzyme Commission (EC): 3.1.1.4 ·	9001-84-7	spla2-type-iii	Secretory Phospholipase A2 (bee venom)	phospholipases A2 enzymes bees extracellular calcium dependent active

Proteins

Eicosanoid Metabolism

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