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Proteins

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Nuclear Receptors/Transcription Factors

Item Number	Product	CAS	Image	Plain Text Name	Synonyms	Keywords
10009524	ChREBP DBD (human recombinant) Carbohydrate Response Element-binding Protein DNA Binding Domain Source: human recombinant N-terminal GST-tagged protein expressed in E. coli · M_r: ~38.3 kDa ·			chrebp-dbd-human-recombinant	GenBank Accession No. BC012925; Carbohydrate Response Element-binding Protein DNA Binding Domain; WS-bHLH; Williams-Beuren Syndrome Chromosome Region 14	EMSA electrophoretic mobility shift assays transcription factors proteins diabetes obesity insulin HLH MLXIPL MIO WBSCR14 endocrinology CAS number # 352845-69-3
10009818	NF-κB (p50) (human recombinant) Active, pure human recombinant enzyme Application(s): positive control for WB · Source: recombinant enzyme expressed in E. coli and purified out of inclusion bodies · M_r: 74.5 kDa · Specific activity: 40 units/mg · Protein concentration: 0.5 mg/ml ·			nf-b-p50-human-recombinant	NF-κB1; Nuclear Factor-κB (p50)	transcription factors proteins homodimers heterodimers p50/p105 p52/p100 RelA c-Rel genes cytokines chemokines immunoreceptors cell adhesion molecules DNA expression phosphorylation p ubiquitination subsequent degradation I.kappa.B.alpha. diseases therapeutics human nfkb nf-kb nf.-kappa.b nf.kappa.b
10009088	PPARα LBD (human recombinant) Purified human recombinant enzyme Source: recombinant His-tagged protein purified from E. coli · M_r: ~34 kDa ·			ppar-lbd-human-recombinant	Peroxisome Proliferator-activated Receptor α Ligand Binding Domain	peroxisomes proliferator-activated receptors PPARs proliferator activated PPARalpha PPAR.alpha. PPARa PPARα PPAR-α PPAR-alpha alpha a α .alpha. PPAR-.alpha. PPAR-a recombinant proteins nuclear family families ligand activated trascription factors heterodimerize retinoic acids genes expression differentiation hNUC1 FAAR PPARβ PPARδ PPARγ liver skeletal muscles brown fats hearts kidneys livers fatty acids FAAH atherosclerotic lesions NSAIDs prostaglandins PGs leukotrienes B4 LTs LTB LTB4 WY 14643 WY-14643 WY14643 hypolipidemic CoA acyl-CoA oxidase enol-CoA hydratase dehydrogenase cytochromes P450 4A amino acids 170-430 E.coli gels electrophoresis coomassie statining western blots immunoblotting WB blotting
61700	PPARγ FL (human recombinant from E. coli) Active, pure human recombinant protein Source: human recombinant N-terminal His-tagged protein expressed in E. coli · M_r: ~60 kDa ·			ppar-fl-human-recombinant-from-e-coli	Peroxisome Proliferator-activated Receptor γ Full Length (human recombinant)	peroxisomes proliferator-activated receptors PPARs proliferator activated PPARgamma PPAR.gamma. PPARg PPARγ PPAR-γ PPAR-gamma gamma g γ .gamma. PPAR-.gamma. PPAR-g human recombinant nuclear receptors ligands activated ligand-activated activates transcription factors heterodimerizes retinoic acids gene expression differentiation hormones subtypes PPARα PPARδ hNUC1 PPARβ pathology obese obesity diabetes atherosclerosis cancers adipose tissues expressed colon immune systems retina DNA binding domains binds DBD transcription factor assays 10006855 gel electrophoresis coomassie stains staining fluorescent displacement ANS rosiglitazone
10009987	PPARγ FL (human recombinant from Sf21 cells) Active, pure human recombinant enzyme Source: human recombinant N-terminal His-tagged protein expressed in Sf21 insect cells · M_r: ~60 kDa ·			ppar-fl-human-recombinant-from-sf21-cells	Peroxisome Proliferator-activated Receptor γ Full Length (human recombinant from Sf21 cells)	proteins binding enzymes PPAR.gamma. PPARgamma diseases obesity diabetes atherosclerosis cancers endocrinology
10007941	PPARγ LBD (human recombinant) Functionally, active protein for drug discovery Source: recombinant N-terminal hexahistidine-tagged protein expressed in E. coli · M_r: ~34 kDa ·			ppar-lbd-human-recombinant	Peroxisome Proliferator-activated Receptor γ Ligand Binding Domain	peroxisomes proliferator-activated receptors PPARs proliferator activated PPARgamma PPAR.gamma. PPARg PPARγ PPAR-γ PPAR-gamma gamma g γ .gamma. PPAR-.gamma. PPAR-g recombinant proteins atherosclerosis diabetes endocrinology genes regulations metabolic syndrome nuclear receptors obese obesity PPAR proteins biochemistry hexahistidine-tagged tagged hexahistidine HIS-tag HIS-tagged HIS N-terminal PPARalpha PPAR.alpha. PPARα PPAR-alpha PPAR-.alpha. PPAR-α PPAR-delta PPAR-.delta. PPAR-δ PPARdelta PPAR.delta. PPARδ hNUC1 FAAR pathology diseases cancers domains LBD ligand binds binding DNA DBD RXR acid-like acid like heterodimerization thiazolidinedione rosiglitazone piolitazone insulin type II E. coli coomassie stains staining western blots blotting immunoblotting WB fluorescent
10007451	PPARδ (human recombinant) Full-length receptor in high-purity form Source: recombinant protein isolated from baculovirus overexpression system in Sf21 cells · M_r: 54 kDa · Protein concentration: 0.12 mg/ml ·			ppar-human-recombinant	PPARβ; Peroxisome Proliferative Activated Receptor δ; Nuclear Hormone Receptor 1; NUC1; FAAR	peroxisomes proliferator-activated receptors PPARs proliferator activated PPARdelta PPAR.delta. PPARd PPARδ PPAR-δ PPAR-delta delta .delta. δ PPAR-.delta. PPAR-d recombinant proteins human atherosclerosis cancers EMSA electrophoretic mobility shift assays endocrinology fluorescence metabolic syndrome nuclear obese obesity biochemistry transcription factors members retionic acids genes expression developments baculovirus Sf21 heterodimerize subtypes hNUC1 FAAR ubiquitously tissues mediator embryo implantation overexpression systems gels coomassie stains staining western blots WB immunoblotting 10006914

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