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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Kit Recommendations for Cysteinyl Leukotriene

• See all kit recommendations

The half-life to LTC4 in plasma is less than 10 minutes, with rapid conversion to LTD4 and LTE4 occurring in the lung. Thus, plasma samples are not recommended for use with Cayman’s LTC4 EIA kit. The Cysteinyl Leukotriene Express EIA Kit, which measures LTC4, LTD4, and LTE4, is better suited for multiple sample types. Normal human urine contains low, but detectable levels of LTE4.

Sample Type Leukotriene C4 EIA Kit
520211 		Leukotriene E4 EIA Kit
520411 		Cysteinyl Leukotriene EIA Kit
500390 		Cysteinyl Leukotriene Express EIA Kit
10009291 		Notes
Cell Culture ✔ ✘ ◆ ✔ LTC4 rapidly exported into media; little or no extracellular metabolism
Bronchiolar Lavage* ◆ ✘ ◆ ● ● Contains LTC4, LTD4, and LTE4
Synovial fluid, ascites, etc.* ◆ ✘ ◆ ● ◆ ● Contains LTC4, LTD4, and LTE4
Plasma/serum* ✘ ◆ ● ◆ ● ◆ ● LTC4 largely metabolized to LTE4 and β-oxidized metabolites
Urine ✘ ◆ ✔ ✔ ◆ ✔ LTC4 largely metabolized to LTE4 and β-oxidized metabolites

◆ purification required

✘ not recommended

✔ validated

* limited sample testing performed with all assays

● potential option
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Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

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