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Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…
Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.

Kit Recommendations for SIRT1 Inhibitor

• See all kit recommendations

Cayman offers two individual kits to screen for SIRT1 inhibitors or activators. Activation of SIRT1, however, is believed to be a substrate-specific event. Cayman’s FRET-based assay does not exhibit substrate-interference and can be used to eliminate false SIRT1 activators found with certain substrates.

Item № Product Plain text name Synonyms Readout Advantages Disadvantages
10010401 SIRT1 Direct Fluorescent Screening Assay Kit SIRT1 Direct Fluorescent Screening Assay Kit Fluorometric
Ex350-360
Em450-465
  • Assay 46 samples in duplicate
  • Screen inhibitors and activators
  • Potential false leads due to a substrate-specific activation event
  • 75 minute incubation
10010991 SIRT1 FRET-Based Screening Assay Kit SIRT1 FRET-Based Screening Assay Kit Fluorometric
Ex335-345,
Em440-465
  • Assay 46 samples in duplicate
  • Screen inhibitors and activators
  • 30 minute incubation
  • Does not have the substrate interaction leading to false leads
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Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

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