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Epigenetics Screening & Lead Discovery Service

Cayman has launched a comprehensive screening laboratory focused on epigenetics that draws on our core strengths in protein production, assay development, chemical synthesis, and medicinal chemistry with a purpose to identify screening hits, to support Hit-to-Lead services, and to sustain Lead Discovery and Development.

Cayman
Epigenetics
Protein
Panel

Cayman
Protein
Core

Cayman
Assay
Development

Cayman
Compound
Collection

Cayman
Medicinal
Chemistry

Cayman Epigenetics Lead Discovery

Cayman Compound Screening Lab

Cayman's screening laboratory is built upon our core
strengths of protein production and assay development.

Cayman’s in-house collection of bioactive compounds

  • Cayman is currently designing and preparing focused, novel SAM-based and substrate-based compound libraries, which will be available on a fee-for-service basis with no licensing fees or royalties. Contact us to learn about items in development. We are also glad to collaboratively design and prepare novel compound libraries.
  • Cayman’s Maybridge HitFinder Diversity Collection
  • Cayman’s Catalog Collection
  • Cayman will also screen customer and third-party collections to drive discovery project needs.

Throughput

Cayman’s Screening Lab has the capability to test compounds arrayed in a 384-well format at a rate of up to 100,000 compounds per week.

People

Dedicated screening lab staff will collaborate with both external partners and Cayman discovery teams to identify screening hits, support Hit-to-Lead services, and sustain lead discovery and development.

Team Role
Screeningperform screens after engaging partners in discussion of target validation, custom protein production, assay development, chemical matter, and screening strategy
Protein Coreexpress and purify both stock and custom point enzymes and receptors
Discovery Chemistry
Biochemistry
EIA		collaborate to support assay development and point validation
Medicinal Chemistrydesign and generate novel compound libraries, resynthesized hit compounds, and provide hit-to-lead services (SAR/point design, synthetic route design, patent and literature search, documentation)
Process Chemistryscale up key intermediates, hits, and lead compounds and optimize synthetic routes

For more information or to receive a quote for these services please contact our sales department at 1-800-364-9897 or email us at sales@caymanchem.com
Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

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