Cayman Chemical | Prostaglandin APIs

Prostaglandin APIs

Cayman Chemical is the New World Leader in the manufacturing of generic, bulk prostaglandins for human and veterinary applications. We have the capacity, the inventory, and the regulatory expertise to solve your API sourcing problems—from Alprostadil to Za—well, let’s call it Latanoprost. Please see the comprehensive list on this page, or contact us for further details.

Download Cayman's Prostaglandin APIs flyer

CaymanProstaglandinAPIs.pdf

Prostaglandin E₁
Alprostadil; U-10136; Caverject; Liple; Minprog; Palux; Prostine VR; Prostivas
Eu. Ph. Purity: 96.0-102.5% Total Impurities: NMT 3.0% USP Purity: 96.0-102.5% Total Impurities: NMT 2.0%	World (US, CA, AU, NZ, ZA, IN); EU (AT, BE, CZ, DK, EE, FI, FR, DE, GR, IE, IT, LU, NL, PT, SK, ES, SE, GB); Other European Countries (NO, CH)
Prostaglandin E₂
Dinoprostone; U-12062; Cerviprost; Minprostin E₂; Pepidil; Propess; Prostarmon-E; Prostin E₂
Eu. Ph. Purity: 97.0-102.0% Total Impurities: NMT 3.0% USP Purity: 97.0-102.0% Total Impurities: NMT 3.0%	World (US, CA, AU, NZ); EU (AT, BE, DK, FI, FR, DE, GR, IE, IT, LU, NL, PT, ES, SE, GB); Other European Countries (CH)
(±)-Cloprostenol (sodium salt)
ICI-80996; Estrumate; Planate
BP (Veterinary) Purity: 97.5-101.0% Total Impurities: NMT 2.0%	World (US, AU); EU (AT, BE, DK, EE, FI, FR, DE, GR, IE, IT, LU, NL, PT, ES, SE, GB); Other European Countries (IS, NO, CH)
(+)-Cloprostenol (sodium salt)
BP (Veterinary) Purity: 97.0-101.0% Total Impurities: NMT 2.5%	EU (AT, CZ, DK, FI, FR, DE, GR, IE, NL, PT, ES)
Oestrophan
(±)-Cloprostenol in Ethanol
Concentration of solution: 9.0-11.0% (w/w) Minimum Purity (+)-cloprostenol: 97.5%	EU (EE)
Superphan
(+)-Cloprostenol in Ethanol
Concentration of solution: 9.0-11.0% (w/w) Minimum Purity (+)-cloprostenol: 97.5%	EU (AT, BE, FR, DE, IE, IT, LU, GB)
Latanoprost
Xalatan; PhXA-41
Purity: 96.0-102.0% Total Impurities: NMT 4.0%	World (US); EU (EE)
Bimatoprost
Purity: 96.0-102.0% Total Impurities: NMT 4.0%	-

*Countries are listed by their ISO country code.

API Custom Synthesis

Active Pharmaceutical Ingredient (API) Synthesis under FDA cGMP guidelines:

Cayman can support your early Clinical Phase active compound needs by developing a custom cGMP synthesis to meet your quality, quantity, and timeline requirements.

If you are interested in receiving additional information (including specifications) or pursuing a quote for one of the PG APIs listed above or a custom API project please contact GMP-API@caymanchem.com. Please note that some information may require a confidentiality agreement.

Cayman also regularly quotes on non-GMP custom synthesis.

HPLC Assay

Cayman is also equipped to provide HPLC analysis of bulk prostaglandin active drug and formulated, aqueous. Our HPLC analytical service uses validated, cGMP-compliant standard operating procedures on IQ/OQ certified instruments. The service has been used for after-market clinical studies, drug manufacturing and quality assurance control.

Please view our Assay Service page for more details.