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Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday.
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Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.
Statins
The “Statin” class of cholesterol-lowering agents function by inhibiting HMG CoA reductase, the enzyme that catalyzes the rate-limiting step in cholesterol biosynthesis. Cayman carries a full line of HMG-CoA reductase inhibitors with varied potency for research applications.
Cholesterol Synthesis Inhibitors
| Item № (salt form) | Statin | Target Enzyme | Ki | Structure |
|---|---|---|---|---|
| 10010337 | Fluvastatin (sodium salt) | HMG-CoA Reductase | 0.3 nM |
|
| 10010338 | Lovastatin | HMG-CoA Reductase | 0.6 nM |
|
| 10010343 | Pravastatin (sodium salt) | HMG-CoA Reductase | 2.3 nM |
|
| 10010344 | Simvastatin | HMG-CoA Reductase | 0.12 nM |
|
Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA
Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640
Copyright 2012 Cayman Chemical Company
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