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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Research Area · Alzheimer's Research

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Item Number Product Sizes & Pricing CAS Purity Image Exclusive Introduction Date Mojo Plain Text Name Synonyms Keywords Interest
10009473 1,2-dipalmitoyl-sn-glycero-3-PC 63-89-8 >98% 2007-01-19 7.301464088397 1-2-dipalmitoyl-sn-glycero-3-pc L-dipalmitoyl Lecithin; L-DPPC; 1,2-dipalmitoyl-sn-glycero-3-Phosphatidylcholine antigens phosphatidylcholines zwitterionic phosphoglycerides proteoliposomes liposomal enzymes g-glutamyl gamma-glutamyl .gamma.-glutamyl transpeptidase erythrocytes immunotherapy immunotherapies GSLs glycosphingolipids phospholipids polyenylphosphatidylcholine 7.301464088397
10312 8,12-iso-iPF2α-VI-1,5-lactone Exclusive - ≥98% ✓ 2009-08-07 6.250128913443 8-12-iso-ipf2-vi-1-5-lactone lactone IPF2α -I iPF2α-VI F2-iP urine lipid peroxidation plasma biomarker oxidative stress 214894-81-2 214894-83-4 6.250128913443
11001 Anatabine New 2743-90-0 ≥95% 2011-11-10 0.311827956989 anatabine alkaloids solanaceae tobacco Alzheimer’s diseases amyloid beta Aβ β-secretase BACE-1 NF-κB inflammation urine nicotine transcription proteins SHSY-5Y cells 0.311827956989
13662 Arecoline (hydrobromide) 300-08-3 ≥95% 2010-08-19 0.299079189687 arecoline-hydrobromide 63-75-2 alkaloids betel nuts Areca agonists muscarinic acetylcholine receptors M1 M2 M3 M4 M5 smooth muscles contractions learning memory dementia Alzheimer’s diseases Methylarecaidin Arecholine Arecoline Arecholin Arecaline Arecolin 0.299079189687
600140 Autophagy/Cytotoxicity Dual Staining Kit - 2009-07-14 84.406214941364 autophagy-cytotoxicity-dual-staining-kit assays kits measuring measurement MDC cell-based autophagy cells cytotoxicity staining autofluorescent autofluorescence substances multilamellar body bodies ions trapping mechanisms membranes lipids probes autophagic vacuoles cultured degradation digestion intracellular lysosomes organelles misfolded proteins microorganisms cytoplasms double membranes autophagosomes autolysosomes homeostasis dysregulation cancers infections aging degenerative diseases stress death apoptosis 84.406214941364
10009021 AVE-1625 Exclusive 358970-97-5 >98% ✓ 2008-04-03 121.810082872928 ave-1625 cannabinoids CB1 receptors schizophrenia parkinsons disease alzheimers disease metabolism obesity SR-141716 lipolysis glycogenolysis antagonist endocrinology neurochemistry 121.810082872928
10227 BACE (human recombinant) - ≥95% 2009-03-09 18.321469613259 bace-human-recombinant Membrane-bound Aspartic Protease; BACE-1; ASP-2; β-Secretase; Memapsin-2 proteins amyloids peptides C-terminus terminal alzheimers neurochemistry 18.321469613259
600070 BACE Inhibitor Screening Assay Kit - 2009-03-26 29.692872928176 bace-inhibitor-screening-assay-kit β-Secretase Inhibitor Screening Assay Kit inhibitors inhibition inhibits assays kits β-sites .beta.-sites b-sites APP cleaving enzymes β-amyloids .beta.-amyloids b-amyloids peptides Ab A.beta. brain neurodegeneration Alzheimer's Diseases AD proteolytic cleavages precursors β-secretases b-secretases γ-secretases .gamma.-secretases g-secretases membranes aspartic C-terminal C-terminus fragments proteolysis therapeutics therapy cascade pathogenesis mice mouse murine transgenics cholinergic dysfunctions HIV humans fluorescents fluorescences fluorometer assays 29.692872928176
10005836 bis(7)-Tacrine 224445-12-9 >98% 2005-04-15 4.350110497238 bis-7-tacrine 1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydro-acridine dimeric congeners amino acridines inhibits inhibitors inhibition acetylcholinesterases Alzheimer's disease hydrogen peroxides apoptosis pheochromocytoma cells neurochemistry neuroscience 4.350110497238
10960 Bisdemethoxycurcumin 24939-16-0 ≥98% 2011-08-09 5.449443726081 bisdemethoxycurcumin BDMC curcumin activators macrophages phagocytosis 1α,25-dihydroxyvitamin D, amyloid-β Alzheimer’s diseases cancers transcription genes expression p300 Wnt/β-catenin iNOS inflammation bisdemethoxy curcumin 33171-05-0 5.449443726081
10009536 CAY10512 Exclusive 139141-12-1 >97% ✓ 2007-07-18 34.820911602210 cay10512 analogs resveratrol nuclear factors NFkB NF-.kappa.B immunity inflammation stress growth apoptosis trans-stilbene activation cancers NF-kB inhibition inhibtors inhibits atherosclerosis 34.820911602210
580110 Clusterin (human) EIA Kit - 2011-08-02 2.154696132597 clusterin-human-eia-kit KUB-1; CLI; SGP-2; AAG4; pADHC-9; TRPM-2; Apo-J; Apolipoprotein J apolipoproteins Up-regulated in Azheimer's diseases brains Ku70-binding proteins 1 sulfated glycoproteins 2 aging-associated genes 4 complement lysis inhibitors testosterone-repressed prostate messages secreted disulfide-linked heterodimeric amyloid lipids bacteria leptin immunoglobulins endocytic receptors LDLs low-density lipoprotein-related LPR2 LPR8 8 endocytosis tissues mammals mammalian cells plasma serums semen cultures media medium developmental remodeling apoptotic neurodegeneration injury stress inhibits inhibition apoptosis carcinogenesis genes CLU ELISAs EIAs enzymes immunoassays kits measures measurements human supernatants 2.154696132597
13197 DAPT 208255-80-5 ≥95% 2010-09-16 16.385745856353 dapt GSI-IX amyloids precursors proteins APP Notch beta amyloid Aβ Alzheimer’s disease inhibitors inhibits inhibition γ-secretase Aβ42 cells signaling signals differentiation GSIIX GSI IX Dipeptides 16.385745856353
10011349 Dimebolin (hydrochloride) 97657-92-6 ≥98% 2010-02-19 10.793650793650 dimebolin-hydrochloride neurodegeneration Alzheimer's diseases Huntington's neuroprotection cognition inhibitors inhibits inhibition calcium channles β-amyloid β amyloid NMDA glutamate receptors mitochondria dimeboline dimebon neurochemistry neuroscience Indoles 10.793650793650
13245 Donepezil 120014-06-4 ≥95% 2010-03-08 3.829033149171 donepezil Aricept® acetylcholine neurotransmitters acetylcholinesterase inhibitors inhibits inhibition central nervous system Alzheimer's diseases cognition memory dementia Donezepil signaling signalling AchE CNS behavior (±)-E 2020 (+/-)-E 2020 E2020 3.829033149171
10007963 E-64 66701-25-5 ≥98% 2009-11-12 54.998232044198 e-64 inhibitors cysteine proteases cathepsins papain calpain irreversible inhibition inhibited E64 E 64 54.998232044198
10007964 E-64c 76684-89-4 ≥98% 2006-08-02 52.925580110497 e-64c EP 475; Loxistatin Acid; NSC 694279 E-64 cysteine protease cell cycle inhibitor E-64d 52.925580110497
13314 Indirubin-3'-monoxime 160807-49-8 ≥98% 2009-07-15 12.044033149171 indirubin-3-monoxime glycogen synthase kinase-3β GSK-3β tau proteins Alzheimer's diseases cyclin-dependent kinases CDK CDK1 cyclin A B E D1 CDK4 CDK2 CDK5 p35 growth proliferation synchronization cells arrest G2/M phases phosphorylation inhibits inhibition inhibitors 12.044033149171
600160 Methionine Sulfoxide Immunoblotting Kit - 2009-12-17 208.421613259668 methionine-sulfoxide-immunoblotting-kit MetO Immunoblotting Kit proteins sulfoxides oxidative modifications residues MSRs reactive oxygen species ROSs methionines oxidations reductases sulfones phagocytosis phagocytotic mitochondrias mitochondrial respirations sulfoxidations age-related diseases cellular cells IgG-containing sera Alzheimer's diseases immunoblots immunoblotting western blots blotting kits assays measures measurements detection tissues lysates semi-pure purified reducing non-reducing sample buffers SDS-PAGE rabbit serums immunizations oxidized corn MetO-DZS18 208.421613259668
700140 Methyltransferase Colorimetric Assay Kit - 2009-04-07 30.658435598239 methyltransferase-colorimetric-assay-kit MT Colorimetric Assay Kit assays kits measures measuring monitoring monitors MTs methylation signal transduction biosynthesis repair gene silencing chromatin regulation S-adenosylmethionine SAM-dependent methyltransferases enzymatic cofactors AdoMet donor modifications DNA Alzheimer's diseases depression Parkinson's multiple sclerosis liver failure cancers enzyme-coupled AdoHcy positive control S-adenosylhomocysteine 30.658435598239
10230 (+)-Muscarine (iodide salt) 24570-49-8 ≥95% 2010-05-06 0.790883977900 -muscarine-iodide-salt neurochemistry 300-54-9 2438-77-9 poisonous mushroom acetylcholine G proteins Alzheimer's disease signal transduction L-muscarine Amanita muscaria 0.790883977900
13136 N-acetyl-D-Glucosamine 7512-17-6 ≥98% 2009-03-13 57.403001841621 n-acetyl-d-glucosamine NAG; Marine Sweet; GlcNAc; NSC 524344 monosaccharide glucose O-GlcNAc alzheimer's disease genes expressions chitin cells signalling signaling post-translational modification signal transduction 57.403001841621
13055 Naphthofluorescein 61419-02-1 ≥98% 2009-03-20 0.670534069981 naphthofluorescein CCG 8295 furin matrix metalloproteinase MTA-MMP MMP2 motility invasion cancer metastasis MMP inhibitors naphthafluorescein 0.670534069981
13224 Neurodazine Exclusive 937807-66-4 ≥98% ✓ 2009-05-18 3.986906077347 neurodazine neurons neuronal differentiation muscles skeletal myoblasts cells neuron-specific enolase neurofilament 200 synapsin 3.986906077347
10009759 NMDA Receptor NR2B Subunit (Phospho-Tyr1252) Polyclonal Antibody - 2007-02-09 1.582196132596 nmda-receptor-nr2b-subunit-phospho-tyr1252-polyclonal-antibody antibodies WB western blots phospho-specific NMDA receptor NMDAR phosphorylation NR2B blotting immunoblotting 1.582196132596
10009760 NMDA Receptor NR2B Subunit (Phospho-Tyr1336) Polyclonal Antibody - 2007-02-09 1.582196132596 nmda-receptor-nr2b-subunit-phospho-tyr1336-polyclonal-antibody antibodies WB western blots phospho-specific NMDA receptor NMDAR phosphorylation NR2B blotting immunoblotting 1.582196132596
10009761 NMDA Receptor NR2B Subunit (Phospho-Tyr1472) Polyclonal Antibody - 2007-02-22 5.497941988950 nmda-receptor-nr2b-subunit-phospho-tyr1472-polyclonal-antibody antibodies WB western blots phospho-specific NMDA receptor phosphorylation NR2B blotting immunoblotting 5.497941988950
600240 Orexin 1 Receptor STEP Reporter Assay Kit (Luminescence) Exclusive - ✓ 2010-03-31 0.869820441989 orexin-1-receptor-step-reporter-assay-kit-luminescence OX1R hypercretins 1 orexins 2 A orexin-2 systems regulates regulator sleep wake cycles feeding cardiovascular autonomic hypothalamic neuropeptides Orexins A Orexins B gut hormones secretions hypothalamus midbrains brainstems G protein-coupled receptors GPCRs orexin-1 OX1R orexin-2 OX2R orexin-A orexin-B sleep disorders narcolepsy humans animals rodents energy homeostasis pain stress antagonists drugs addictions withdrawals therapeutics obesity Surface transfection expression protocols solid phase transient transfection technology originus patents USPT US6897067 US6902933 US7056741 US 6897067 6902933 7056741 DNA deoxyribonucleases adherent cells receptor-mediated luminescent secretory alkaline phosphatases SEAP signal transduction cascades culture medium luminescence-based high throughput screening screens agonists 0.869820441989
600250 Orexin 2 Receptor STEP Reporter Assay Kit (Luminescence) Exclusive - ✓ 2010-03-31 1.019337016574 orexin-2-receptor-step-reporter-assay-kit-luminescence OX2R hypercretins 1 orexin 2 systems regulates regulator sleep wake cycles feeding cardiovascular autonomic hypothalamic neuropeptides Orexins A Orexins B gut hormones secretions hypothalamus midbrains brainstems G protein-coupled receptors GPCRs orexin-1 OX1R orexin-2 OX2R orexin-A orexin-B sleep disorders narcolepsy humans animals rodents energy homeostasis pain stress antagonists drugs addictions withdrawals therapeutics obesity Surface transfection and expression protocols solid phase transient transfection technology originus patents USPT US6897067 US6902933 US7056741 US 6897067 6902933 7056741 DNA deoxyribonucleases adherent cells receptor-mediated luminescent secretory alkaline phosphatases SEAP signal transduction cascades culture medium luminescence-based high throughput screening screens agonists 1.019337016574
700560 PAD4 Inhibitor Screening Assay Kit - 2011-05-04 27.041660720405 pad4-inhibitor-screening-assay-kit Protein Arginine Deiminase 4; Peptidylarginine Deiminase 4 kits assays measures measurements proteins arginines deiminases PADs guanidine-modifying enzymes peptidylarginine deiminase amidinotransferases nucleus homodimers transcriptional coregulator catalyzes residues citrulline calcium-dependent substrates histones H2A H3 H4 post-translational modifications genes regulations autocitrullination inhibits enzymatic activity cells rheumatoid arthritis citrulline-containing immune response autoantibodies tissues multiple sclerosis Alzheimer's diseases glaucoma cancers human deiminates N-α-benzoyl-L-arginine ethyl esters BAEE kinetic ammonia detectors fluorescent fluorescence 27.041660720405
10218 PCSK9 Monoclonal Antibody (Clone 15A6) - 2008-10-29 13.274198895027 pcsk9-monoclonal-antibody-clone-15a6 Proprotein Convertase Subtilisin Kexin 9; NARC-1 antibodies proproteins serine protease lipoproteins LDLs low density neural apoptosis-regulated convertase 1 blotting ligands western immunoblotting WB blots 13.274198895027
10010518 PD 146176 4079-26-9 ≥98% 2009-02-25 31.652648041431 pd-146176 NSC 168807 atherosclerosis 15-LOs 15-lipoxygenases oxidant injury injuries apoptosis amyloid β proteins inhibitors inhibits inhibitions Alzheimers disease oxidative stress pd146176 31.652648041431
512031 Prostaglandin D2 EIA Kit - 2010-07-19 268.101938305709 prostaglandin-d2-eia-kit PGD2 ELISA Kit PGD2 prostaglandins measures kits eias enzyme immunoassays ELISAs measurements brains glutathione-independent lipocalin-type synthases L-PGDS cerebrospinal fluid CSF physiologic sleep rats humans mast cells leukocytes intracellular myeloid-type glutathione-dependent vascular 11β-PGF2α eicosanoids cultures lysates biosynthesis serum proteins albumin media medium methoximine derivatives PGD2-MOX competitive enzymatic reactions 268.101938305709
512041 Prostaglandin D2 Express EIA Kit - 2010-07-19 125.652167445813 prostaglandin-d2-express-eia-kit PGD2 Express ELISA Kit PGD2 prostaglandins measures kits eias enzyme immunoassays ELISAs measurements brains glutathione-independent lipocalin-type synthases L-PGDS cerebrospinal fluid CSF physiologic sleep rats humans mast cells leukocytes intracellular myeloid-type glutathione-dependent vascular 11β-PGF2α eicosanoids cultures lysates biosynthesis serum proteins albumin media medium methoximine derivatives PGD2-MOX competitive enzymatic reactions 125.652167445813
10012554 Resolvin D1 Exclusive 872993-05-0 ≥95% ✓ 2008-06-06 256.881973164956 resolvin-d1 RvD1; 17(S)-Resolvin D1 EPA DHA inflammation antiinflammatory anti-inflammatory immune responses aspirin LOX peritonitis LOS neurochemistry resolvins 256.881973164956
13332 (S)-Glycyl-H-1152 (hydrochloride) Exclusive 913844-45-8 ≥98% ✓ 2010-01-27 51.846950276243 -s-glycyl-h-1152-hydrochloride Rho Kinase Inhibitor IV Rho kinases ROCK-I p160ROCK ROCK-II G protein Rho cytoskeletons adhesions proliferation smooth muscles contraction stem cells inhibitors inhibition inhibited Fasudil hydrochloride ROCK IV h1152 h-1152 h 1152 51.846950276243
10011382 sPLA2 (human Type IIA) Western Ready Control Exclusive - ✓ 2008-03-17 32.325840568271 spla2-human-type-iia-western-ready-control Secretory Phospholipase A2 (human Type IIA); sPLA2 (human synovial) WB western blots blotting immunoblotting 32.325840568271
11190 Termitomycamide B New 1254277-89-8 ≥97% 2012-01-31 173.333333333333 termitomycamide-b mushrooms extracts ER stress apoptosis endoplasmic reticulum neuroscience proteins misfolding Parkinson’s diseases Alzheimer’s prions fatty acids cells death termites termitomycamides Termitomyces titanicus Neuro2a 173.333333333333
13237 Thiamet G Exclusive 1009816-48-1 ≥97% ✓ 2009-06-25 34.702679558011 thiamet-g inhibitors inhibits inhibitions tau alzheimers disease O-GlcNAc OGlcNAc O-GlcNAcase OGlcNAcase O-GlcNAcylation OGlcNAcylation Thiamet-G 34.702679558011
10009085 U-18666A 3039-71-2 >95% 2007-01-19 30.859149171270 u-18666a Niemann-Pick type C NPC apoptosis neuronal death Alzheimers AD neurodegeneratives diseases trafficking unesterified ER cells membranes cateracts epilepsy Free cholesterol loading NSC 70801 Endoplasmic reticulum atherosclerosis inhibits inhibitors inhibition endosomes lysomes oxidosqualene cyclases atherosclerosis 30.859149171270
13033 Valproic Acid (sodium salt) 1069-66-5 ≥95% 2009-10-21 27.022965009207 valproic-acid-sodium-salt Sodium Valproate; 2-Propylvaleric Acid valeric acids anticonvulsant seizures inhibitors histones deacetylases HDAC glycogen synthase kinases GSK3 inositol-1,4,5-trisphosphate IP3 combination therapy cancers Alzheimer's diseases stem differentiation self-renewal 27.022965009207
10790 Xanomeline oxalate 141064-23-5 ≥98% 2011-06-14 0.382872928177 xanomeline-oxalate Lumeron; Memcor; LY246708 agonists muscarinic receptors acetylcholine psychosis antipsychotic memory neurotransmitters neurological Alzheimer’s diseases M1-preferring 0.382872928177
10229 β-Amyloid (1-8, A2V) Peptide Exclusive - ✓ 2009-05-08 44.783863950276 -amyloid-1-8-a2v-peptide Aβ; β-amyloid (1-8) dominant negative; Aβ 1-8 mutant peptides fibrils antibodies inhibitors amyloid .beta. betaamyloid aggregation inhibitors 44.783863950276
10241 β-Amyloid (1-8) Peptide Exclusive - ✓ 2009-06-30 50.802967640094 -amyloid-1-8-peptide Aβ peptides fibrils antibodies inhibitors amyloid .beta. 50.802967640094
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