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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Research Area · Apoptosis

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Item Number Product Sizes & Pricing CAS Purity Image Exclusive Introduction Date Mojo Plain Text Name Synonyms Keywords Interest
34720 15(S)-HETE 54845-95-3 ≥98% 33.067837411207 15-s-hete soybean 15-LOs asthma airway 15-lipoxygenases monohydroxy fatty acids 15S-HETES 15-HETES arachidonic 15(S)-HETEs 15(S)HETEs potato polyunsaturated 15HETEs 33.067837411207
334720 15(S)-HETE-d8 84807-87-4 ≥99% deuterated product 39.003388581951 15-s-hete-d8 GC/MS deuterium isotopes 15-HETE-d8 standards 15S-HETE-d8 15(S)HETE-d8 deuterated GC-MS LC/MS LC-MS 15-HETEs 15(S)-HETEs 15S-HETEs 15(S)HETEs hydroxy fatty acids mass spectrometry 15HETE 39.003388581951
534721 15(S)-HETE EIA Kit - 73.417918968692 15-s-hete-eia-kit 15(S)-HETE ELISA Kit solid plates 15(S)-HETEs 15S-HETEs measures kits eias enzyme immunoassays ELISAs 15(S)HETEs 15HETEs assays 73.417918968692
10007251 15(S)-HETE Lipid Maps MS Standard 54845-95-3 ≥98% 2009-02-17 17.652116447088 15-s-hete-lipid-maps-ms-standard soybean 15-LOs asthma airway 15-lipoxygenases monohydroxy fatty acids 15S-HETES 15-HETES arachidonic 15(S)-HETEs 15(S)HETEs potato polyunsaturated MS mass spectrometry standards 15HETE 17.652116447088
10005229 2,3-DCPE (hydrochloride) - ≥98% 2006-09-15 13.960662983425 2-3-dcpe-hydrochloride apoptosis Bcl-XL p21 ERK cancers cells cycles proapoptotic in vitro S-phase arrest upregulate activates activation 13.960662983425
11097 25-hydroxy Cholesterol New 2140-46-7 ≥98% 2012-02-08 114.684567219153 25-hydroxy-cholesterol 16505-96-7 oxysterol cholesterol SREBP sterols regulatory elements binding proteins atherosclerosis anticancer apoptosis immunosuppressive Bcl-2 caspases atherosclerosis antitumor tumors LXR-RXR ligands T cells macrophages 114.684567219153
11099 25-hydroxy Cholesterol-d6 New 88247-69-2 ≥99% deuterated form (d1-d6) 2012-01-27 104.017900552485 25-hydroxy-cholesterol-d6 deuterated deuterium GC/MS GC-MS LC/MS LC-MS mass spectrometry MS 16505-96-7 oxysterol cholesterol SREBP sterols regulatory elements binding proteins atherosclerosis anticancer apoptosis immunosuppressive Bcl-2 caspases atherosclerosis antitumor tumors LXR-RXR ligands T cells macrophages 104.017900552485
10397 3-amino Benzamide New 3544-24-9 ≥98% 2011-10-07 2.289024419063 3-amino-benzamide 3-(Aminocarbonyl) Aniline; 3-Carboxamidoaniline poly(ADP-ribose) polymerases PARPs DNA repairs DNA strands breaks apoptosis inflammation atherosclerosis neruogenesis cancers angiogenesis signaling cellular responses inhibits inhibitor inhibition telomere shortening shortens stimulates mediated mediates PARP-mediated 2.289024419063
10009856 7-AAD Cell Viability Assay Kit - 2008-10-29 28.530144918489 7-aad-cell-viability-assay-kit 7-Amino Actinomycin D Cell Viability Kit kits 7AAD measurement cells fixation blocking cytoxicity effects environmental toxins drug fluorescence fluorescent cell-based assays cell based assay cba 28.530144918489
600120 7-AAD/CFSE Cell-Mediated Cytotoxicity Assay Kit - 2009-08-05 59.067738752959 7-aad-cfse-cell-mediated-cytotoxicity-assay-kit 7-Amino Actinomycin D/5-(6)-Carboxyfluorescein Diacetate Succinimidyl Ester 7-amino actinomycin D/5-(6)-carboxyfluorescein diacetates succinimidyls esters assays kits measuring measurement kits 5-(6) 5,6 5-6 7AAD cells cytoxicity cell-based cba cytolysis target effector T lymphocytes NK natural killer autoimmune systems pathological cancers multiple sclerosis granule exocytosis pathways Fas diseases graft host 51chromium 51Cr green fluorescent fluorescence probes red propidium iodide dead effector carboxyfluorescein succinimidyl esters dyes damaged DNA deoxyribonucleic acids quantify quantification single staining 59.067738752959
53400 (±)9,10-DiHOME 263399-34-4 ≥98% 7.355874769797 -9-10-dihome Leukotoxin diol epoxides epoxygenase leukotoxin cytochrome P450 (+/-)9(10)-DiHOMes (+/-)9,10-DiHOMes CYP450 7.355874769797
10009993 (±)9,10-DiHOME-d4 - ≥99% deuterated forms (d1-d4) 2007-06-01 4.717458563536 -9-10-dihome-d4 Leukotoxin diol-d4 epoxides epoxygenase leukotoxin cytochrome P450 (+/-)9(10)-DiHOMes (+/-)9,10-DiHOMes CYP450 deuterated duteriums 4.717458563536
52400 (±)9(10)-EpOME - ≥98% 5.713991712707 -9-10-epome Leukotoxin; 9,10-EODE epoxides epoxygenasse leukotoxin cytochrome P450 (+/-)9(10)-EpOMEs (+/-)9,10-EpOMEs epoxy fatty acids (±)9(10)-epome 5.713991712707
10009995 (±)9(10)-EpOME-d4 - ≥99% deuterated forms (d1-d4) 2007-06-01 2.314217311234 -9-10-epome-d4 Leukotoxin-d4; 9,10-EODE-d4 epoxides epoxygenasse leukotoxin cytochrome P450 (+/-)9(10)-EpOMEs (+/-)9,10-EpOMEs epoxy fatty acids deuterated deuterium 2.314217311234
10008051 Acid Phosphatase Assay Kit - 2006-09-20 5.593591160221 acid-phosphatase-assay-kit aps hydrolase eznymes prostate pap tartrate resistant assays 5.593591160221
10006908 Adipogenesis Assay Kit - 2006-08-18 82.688214714396 adipogenesis-assay-kit obese obesity cells cycle differentiation inhibits inhibitors inhibition adipocytes cancers origin 3T3-L1 model drug screening adipokines endocrinology cell-based assays cell based assay cba 82.688214714396
10009381 Adipolysis Assay Kit - 2007-07-30 59.419943270406 adipolysis-assay-kit obese obesity cells cycle differentiation inhibits inhibitors inhibition adipocytes cancers origin 3T3-L1 model drug screening adipokines lipolysis 3T3L1 kits assays FFA adipocytes endocrinology cell-based assay cell based assay cba 59.419943270406
10010129 AG-041R Exclusive 199800-49-2 ≥98% ✓ 2008-12-16 40.045359116022 ag-041r CCKs gastrin receptors antagonist cancers proliferations apoptosis NS-398 NS398 NS 398 40.045359116022
10010311 AG-490 133550-30-8 >98% 2007-12-01 9.933476058931 ag-490 PTK tyrosine kinase inhibitors inhibition inhibits antiproliferatives tyrphostins leukemia Jak-2 Jak2 AG490 9.933476058931
360773 AIF Blocking Peptide - 1.615948434622 aif-blocking-peptide Apoptosis-Inducing Factor; Programmed Cell Death Protein 8 human peptides controls factors WB western blots blotting antibodies apoptosis 1.615948434622
160773 AIF Polyclonal Antibody - 0E-12 aif-polyclonal-antibody Programmed Cell Death Protein 8; Apoptosis-Inducing Factor Polyclonal Antibody apoptosis antibodies western blots blotting WB antisera antiserum factors cancers immunoblotting 0E-12
600300 Annexin V FITC Assay Kit - 2010-05-11 81.388892443806 annexin-v-fitc-assay-kit assays kits measures measurements apoptosis cells death cycles tissues homeostasis dysregulation neurodegenerative diseases ischemic damages autoimmune disorders cancers drugs discovery signaling pathways membranes phospholipids phosphatidylserines phosphatidylethanolamines leaflets bilayers externalizations residues plasma phospholipids binding proteins fluorochrome-labeled fluorochromes fluorescence microscopy flow cytometry FC plate readers TUNEL TdT-mediated dUTP Nick-End Labeling analysis ISEL in situ end labeling DNA laddering detection fragmentation FITC-conjugated fluoresceins 81.388892443806
360780 Apaf-1 Blocking Peptide - 2.376077348066 apaf-1-blocking-peptide peptides controls apoptosis cell death caspases CED-4 Apaf2 Apaf3 Apaf-2 Apaf-3 Apafs antibodies Apaf1 CED4 protease-activating factors proteases 2.376077348066
160780 Apaf-1 Polyclonal Antibody - 2.007955801104 apaf-1-polyclonal-antibody Apoptosis Protease-Activating Factor 1 apoptosis cell death caspases CED-4 Apaf2 Apaf3 Apaf-2 Apaf-3 Apafs antibodies Apaf1 CED4 western blots blotting WB protease-activating factors proteases antisera antiserum cancers immunoblotting 2.007955801104
10010750 Apoptotic Blebs Assay Kit - 2008-02-29 48.729872503187 apoptotic-blebs-assay-kit assays fluorescence fluorescent fluorometric apoptosis kits cell-based assay cell based assay cba 48.729872503187
160737 ARC Polyclonal Antibody - 10.826063535911 arc-polyclonal-antibody Apoptosis Repressor with CARD apoptosis cell death domain DD CARD caspase antibodies western blots blotting WB antisera antiserum cancers immunoblotting IP immunoprecipitation 10.826063535911
600140 Autophagy/Cytotoxicity Dual Staining Kit - 2009-07-14 84.406214941364 autophagy-cytotoxicity-dual-staining-kit assays kits measuring measurement MDC cell-based autophagy cells cytotoxicity staining autofluorescent autofluorescence substances multilamellar body bodies ions trapping mechanisms membranes lipids probes autophagic vacuoles cultured degradation digestion intracellular lysosomes organelles misfolded proteins microorganisms cytoplasms double membranes autophagosomes autolysosomes homeostasis dysregulation cancers infections aging degenerative diseases stress death apoptosis 84.406214941364
10010266 BAY-11-7082 19542-67-7 ≥98% 2008-07-25 29.500721085946 bay-11-7082 inhibitors inhibits inhibition NFkB NF-.kappa.B NF-kB NF-kappaB TNF.alpha. TNFa TNFalpha I.kappa.B-.alpha. IkB-a IkappaB-alpha inflammation cytokine cell adhesion ICAM-1 ICAM1 VCAM-1 VCAM1 E-selection Eselection Bay 11-7082 BAY-117821 Bay117082 BAY 117821 29.500721085946
10009644 BAY-43-9006 New 284461-73-0 ≥98% 2011-09-13 30.859047876037 bay-43-9006 Sorafenib; Nexovar® inhibitors raf-1 b-raf receptors tyrosine kinases VEGF VEGFR PDGF PDGFR cancers angiogenesis apoptosis tumors cells cellular proliferation Flt-3 c-KIT carcinoma growth factor tosylate 30.859047876037
10011385 Bim/BOD (IN) Polyclonal Antibody - 2008-04-10 2.224364640884 bim-bod-in-polyclonal-antibody apotosis BH3 Bcl-2 Bcl-XL cancer immunoblotting WB IHC antibodies western blotting antiserum blots immunohistochemistry 2.224364640884
13013 (−)-Blebbistatin 856925-71-8 ≥98% 2009-04-16 30.649999999999 -blebbistatin (S)-Blebbistatin inhibitors muscles myosin ATPase smooth muscle bleb apoptosis cell migration chemotaxis cytokinesis cells division growth UV light blebs (-)-(S)-Blebbistatin 30.649999999999
13165 (+)-Blebbistatin - ≥98% 2009-04-16 36.576353591160 -blebbistatin (R)-Blebbistatin inhibitors muscles myosin ATPase smooth muscle bleb apoptosis cell migration chemotaxis cytokinesis cells division growth UV light (+)-(R)-Blebbistatin inhibition inhibited 36.576353591160
13186 (±)-Blebbistatin 674289-55-5 ≥98% 2009-06-09 49.568563535911 -blebbistatin inhibitors muscles myosin ATPase smooth bleb apoptosis cells migration chemotaxis cytokinesis division growth UV lights 49.568563535911
10007958 C-12 NBD Ceramide 202850-01-9 >98% 2006-04-12 20.544452629425 c-12-nbd-ceramide N-C12-NBD-D-erythro-Sphingosine ceramides cerimidases fluorescent fluorescence substrates N-acyl fatty acids sphingosine bases isoforms neutral alkalines catalytic pH analogs hydrolyzed hydrolysis P. aeruginosa mouse liver mammalian cells lines kinases sphingomyelin synthases 20.544452629425
10008097 C-12 NBD-dihydro-Ceramide - >98% 2006-04-13 16.061404308807 c-12-nbd-dihydro-ceramide N-C12-NBD-D-erythro-dihydro-Sphingosine ceramides cerimidases fluorescent fluorescence substrates N-acyl fatty acids sphingosine bases isoforms neutral alkalines catalytic pH analogs hydrolyzed hydrolysis P. aeruginosa mouse liver mammalian cells lines kinases sphingomyelin synthases 16.061404308807
10681 C-16 Ceramide 24696-26-2 ≥98% 2011-03-08 3.600925414364 c-16-ceramide Palmitoyl Ceramide sphingomyelins apoptosis ceramides lipids membranes second messengers C16 ceramides longevity assurance homologs 6/LASS6 Ceramides C 16 3.600925414364
10724 C-20 Ceramide 7344-02-7 ≥98% 2011-03-08 3.174785911602 c-20-ceramide sphingomyelins apoptosis differentiation brains C20-ceramide C20:0 ceramides 20:0 synthesis 1 2 synthases 3.174785911602
10005270 C75 191282-48-1 >98% 2004-09-22 39.534110497237 c75 inhibits inhibitors inhibition fatty acids synthases FAS cerulenin cytotoxicity apoptosis cancers anorexigenic stable weight loss feeding endocrinology 39.534110497237
13916 Caspase-14 Monoclonal Antibody (Clone 70A1426) - 2010-09-13 5.208805779855 caspase-14-monoclonal-antibody-clone-70a1426 caspases cysteine proteases mediators programmed cells death apoptosis prodomain catalytic subunits pentapeptides QACRG embryonic tissues ontogenesis western blots immunoblotting blotting WB FC flow cytometry antibodies 14 fourteen 5.208805779855
13907 Caspase-1 Monoclonal Antibody (Clone 14F468) - 2010-07-12 4.351128650355 caspase-1-monoclonal-antibody-clone-14f468 IL-1β Converting Enzyme antibodies caspases caspase1 cysteine proteases cell death apoptosis prodomain catalytic subunits receptors ligand growth factor CED-3 CED3 western blots blotting immunoblotting WB immunohistochemistry IHC proteins IL-1β ICE IL1β IL-1b IL1b apoptosis inflammatio 4.351128650355
13906 Caspase-1 Polyclonal Antibody - 2010-07-12 3.700205209155 caspase-1-polyclonal-antibody IL-1β Converting Enzyme antibodies caspases caspase1 cysteine proteases cell death apoptosis prodomain catalytic subunits receptors ligand growth factor CED-3 CED3 western blots blotting immunoblotting WB immunohistochemistry IHC proteins ICE IL1β IL-1β 3.700205209155
13908 Caspase-2 Monoclonal Antibody (Clone 18E809.3) - 2010-07-21 3.882838929026 caspase-2-monoclonal-antibody-clone-18e809-3 caspases cysteine antibodies western blots blotting immunoblotting WB cell death apoptosis mRNA caspase-3 serine protease 2 granzyme B lytic granules cytotoxic lymphocytes 3.882838929026
10009135 Caspase-3 Fluorescence Assay Kit - 2007-08-06 62.426918354818 caspase-3-fluorescence-assay-kit assays kits caspases fluorescent cells death apoptosis necrosis aspartate-specific cysteinyl fluorescence fluorometric proteases family mitochondrial mitochondria electrons transport oxidative phosphorylation adenosine triphosphate ATP cytochromes C caspase-9 anti-cancers drugs N-Ac-DEVD-N'-MC-R110 HTS high throughput screening N-Ac-Asp-Glu-Val-Asp-CHO cell-based assay cell based assay cba 62.426918354818
360745 Caspase-3 (human) Blocking Peptide - 0.575291117722 caspase-3-human-blocking-peptide Yama; ICE3; CPP32; Apopain control peptides blots blotting western cpp-32 ice-3 apoptosis effectors caspases cell death wb antibodies 0.575291117722
160745 Caspase-3 (human) Polyclonal Antibody - 13.479407332998 caspase-3-human-polyclonal-antibody Yama Polyclonal Antibody; ICE3 Polyclonal Antibody; CPP32 Polyclonal Antibody; Apopain Polyclonal Antibody antibodies blots blotting western cpp-32 ice-3 apoptosis effectors caspases cell death wb antisera antiserum cancers immunoblotting IHC immunohistochemistry 13.479407332998
13909 Caspase-3 Monoclonal Antibody (Clone 31A1067) - 2010-08-10 3.700205209155 caspase-3-monoclonal-antibody-clone-31a1067 ICE3; Apopain; Yama; CPP32 caspases caspase 3 cysteine proteases cell death apoptosis antibodies western blots blotting immunoblotting WB immunohistochemistry IHC frozen paraffin-embedded paraffin embedded yama CPP32 apopain codes PARP poly(ADP-ribose) polymerase DNA-PK DNAPK DNA PK actin GAS2 pro-caspase procaspase pro CrmA small large subunits 3.700205209155
13911 Caspase-3 Monoclonal Antibody (Clone 31A893) - 2010-09-07 3.700205209155 caspase-3-monoclonal-antibody-clone-31a893 Yama; ICE3; CPP32; Apopain caspases caspase 3 cysteine proteases cell death apoptosis antibodies western blots blotting immunoblotting WB immunohistochemistry IHC frozen paraffin-embedded paraffin embedded yama CPP32 apopain codes PARP poly(ADP-ribose) polymerase DNA-PK DNAPK DNA PK actin GAS2 pro-caspase procaspase pro CrmA small large subunits 3.700205209155
13912 Caspase-7 Monoclonal Antibody (Clone 25B881.1) - 2010-09-09 3.700205209155 caspase-7-monoclonal-antibody-clone-25b881-1 caspases seven caspase 7 cysteine proteases programmed cell death apoptosis catalytic subunits MCH3 MCH-3 MCH p20 p12 caspase-3 western blots immunlotting blotting WB immunohistochemistry IHC 3.700205209155
13914 Caspase-8 Monoclonal Antibody - biotin (Clone 90A992) - 2010-09-09 0.225217925107 caspase-8-monoclonal-antibody-biotin-clone-90a992 caspases eight 8 cysteine proteases key mediators programmed cells death apoptosis FLICE ICE CD95 CD-95 CDs 95 subunits a2be active enzyme inhibitors inhibits inhibition ELISA biotinylated biotins 0.225217925107
13913 Caspase-8 Monoclonal Antibody (Clone 90A992) - 2010-09-09 3.700205209155 caspase-8-monoclonal-antibody-clone-90a992 caspases eight 8 cysteine proteases key mediators programmed cells death apoptosis FLICE ICE CD95 CD-95 CDs 95 subunits a2be active enzyme inhibitors inhibits inhibition antibodies western blots blotting immunoblotting WB immunohistochemistry IHC flow cytometry FC 3.700205209155
13915 Caspase-9 (carboxy-terminal divergent) Polyclonal Antibody - 2010-09-09 3.700205209155 caspase-9-carboxy-terminal-divergent-polyclonal-antibody CTD caspases nine 9 apaf-1 apaf1 apaf 1 one binds binding activation activates active cleaves proteases proteolytic cleavage apoptosis inducers TNFa TNF-a TNF a TNFα TNF-α α TNFalpha TNF-alpha alpha TNF.alpha. TNF-.alpha. .alpha. TRAIL CD-95 CD95 CDs 95 FADD TRADD tissues C-terminal C-terminus terminal terminus C proteins peptides Casp-9 Casp9 Casp genes cytoplasm nucleus cytochrome c dominant-negative western blots blotting immunoblotting WB 3.700205209155
160790 Caspase-9 Polyclonal Antibody - 10.669451197053 caspase-9-polyclonal-antibody MCH6 Polyclonal Antibody; ICE-LAP6 Polyclonal Antibody; Apaf-3 Polyclonal Antibody apoptosis cell death Apaf-1 apafs caspase-3 caspases antibodies Apaf1 western blots blotting WB an tisera antiserum cancers immunoblotting 10.669451197053
72510 CAY10406 - >98% 25.736419889502 cay10406 selectively inhibits inhibitors caspase-3 caspase-7 apoptosis apoptotic signal inhibition CAY-10406 25.736419889502
70635 CAY10416 443919-96-8 >95% 2007-07-24 28.782914364640 cay10416 COX-2 cyclooxygenases 5-LO lipoxygenases inflammation inhibitors prostates cancers PC3 LNCaP carcinomas apoptosis inhibition inhibits chemotherapy cells lines 28.782914364640
10005019 CAY10433 537034-17-6 >98% 2005-01-05 53.218406657117 cay10433 BML-210; N-phenyl-N'-(2-Aminophenyl)hexamethylenediamide HDAC deacetylases histone inhibits inhibitors inhibition cancer cells differentiation gene expression regulation Trichostatin A nuclear extracts deacetylation transcription factors FOXO3 SIRT1 H2O2 hydrogen peroxides BML210 53.218406657117
10004177 CAY10443 582314-48-5 >98% 2004-06-17 4.262685082872 cay10443 (S)-Indan-1-yl 3,4-dichlorobenzylcarbamate DNA binding anti-oncogenic apoptosis cancer p53 re-activator reactivator induces apoptotic re-activation reactivation antioncogenic 4.262685082872
10008872 CAY10503 - >98% 2007-08-02 87.804419889503 cay10503 apoptosis antiproliferation cancers differentiation HL60 cells cycles proliferative positive markers CD14 CD11b CD11c monocytic granulocytic 87.804419889503
10010043 CAY10561 Exclusive 933786-58-4 >98% ✓ 2008-03-06 27.155911602210 cay10561 Pyrazolylpyrrole ERK Inhibitor MEK Ras Raf ERK2 proliferation cell cycles cancers apoptosis inhibition inhibit inhibitors 27.155911602210
10011256 CAY10577 300675-28-9 ≥95% 2008-09-02 0.867403314917 cay10577 inhibitors inhibits inhibition CK2 kinase cell signaling apoptosis cancers 0.867403314917
10011264 CAY10578 19231-60-8 ≥95% 2008-08-26 0.867403314917 cay10578 inhibitors inhibits inhibition kinase cell signaling CK2 apoptosis cancers isoindolineacetic acids 0.867403314917
13291 CAY10616 Exclusive 586410-08-4 ≥98% ✓ 2009-12-01 20.623049723757 cay10616 resveratrols apoptosis cancers leukemia HL-60 cells HL60 HL 60 multidrug-resistance multidrug resistance multi-drug multi-drug-resistant daunorubicin etoposides citarabines phenols cytarabines HL60R 20.623049723757
13836 CAY10625 137346-42-0 ≥95% 2010-06-23 1.388011049723 cay10625 apoptosis Smac Diablo Survivin cancers antagonists INCENP doxorubicin caspase-3 caspase-7 Aurora B kinases Borealin caspases cell-permeable antagonists smac/diable smac-diablo 1.388011049723
10004985 Caylin-1 - >98% 2005-09-09 14.983093922652 caylin-1 caylin1 mdm-2 cancer Nutlin-3 analogs p53 inhibits inhibitors inhibition interaction Mdm2 negative regulators activity chlorine substituents phenyl rings growth HCT-116 cells promotes 14.983093922652
10005002 Caylin-2 - >98% 2004-07-12 13.664419889502 caylin-2 apoptosis cancer p53 inhibits inhibitors induces apoptotic re-activation reactivation antioncogenic tumors xenografts HCT-116 caylin2 13.664419889502
13172 CBHA 174664-65-4 ≥98% 2009-06-24 33.912871516690 cbha Histone Deacetylase Inhibitor II; m-Carboxycinnamic Acid bis-Hydroxamide histones deacetylase HDACs HDAC1 HDAC3 apoptosis cancers neuroblastoma tumors retinoic acids inhibitors inhibits inhibition 33.912871516690
10339 CD25 Monoclonal PE Antibody (Clone 143-13) Exclusive - ✓ 2010-06-09 19.670179558011 cd25-monoclonal-pe-antibody-clone-143-13 p55; IL-2Rα; Tac; Interleukin-2 receptor α subunit antibodies antiserum IF FC flow cytometry immunofluorescence interleukins 2 IL-2 IL2 cytokines immunochemical IF 19.670179558011
10004837 CD27 Monoclonal Antibody (Clone 203.6) - 2005-09-16 7.419065796082 cd27-monoclonal-antibody-clone-203-6 antibodies antisera antiserum IHC immunohistochemistry ICC immunocytochemistry FACS flow cytometry type II transmembranes glycoproteins leukocytes proteins tetraspanin superfamily antigens alternative splicing isoforms human B cells pro-B plasma T macrophages neutrophils platelets erythrocytes Anti-CD37 immunophenotyping neoplasia hairy chronic lymphocytic non-Hodgkin's lymphoma expression lymphocytes T cells NK activated memory monocytes granulocytes dendritic B anti-CD45 mAB lymphoid malignancies malignant cancer FC 7.419065796082
10004835 CD34 Monoclonal Antibody (Clone ICO-115) - 2005-09-16 4.512881427964 cd34-monoclonal-antibody-clone-ico-115 antibodies antisera antiserum ICC immunocytochemistry FACS flow cytometry type I transmembranes glycoproteins proteins antigens isoforms stem cells embryonic fibroblasts neurons Anti-CD34 differential staining acute leukemias cancers malignant malignancies ICO115 FC 4.512881427964
10004718 CD37 Monoclonal Antibody (Clone IPO-24) - 2005-09-16 4.867584128578 cd37-monoclonal-antibody-clone-ipo-24 antibodies antisera antiserum IHC immunohistochemistry ICC immunocytochemistry FACS flow cytometry type III transmembranes glycoproteins leukocytes proteins tetraspanin superfamily antigens alternative splicing isoforms human B cells pro-B plasma T macrophages neutrophils platelets erythrocytes Anti-CD37 immunophenotyping neoplasia hairy chronic lymphocytic non-Hodgkin's lymphoma expression lymphocytes T cells NK activated memory monocytes granulocytes dendritic B anti-CD45 mAB lymphoid malignancies malignant cancer FC 4.867584128578
10009852 CD4/CD8 Monoclonal FITC/PE Antibody (Clone RIV7/OKT-8) - 2008-09-03 0.485303867403 cd4-cd8-monoclonal-fitc-pe-antibody-clone-riv7-okt-8 antibodies antisera antiserum FC flow cytometry human whole blood cells lysis white CD4-CD8 CD4+CD8 IF immunofluorescence 0.485303867403
10004604 CD95 Monoclonal Antibody (Clone IPO-4) - 2004-06-17 1.484942909760 cd95-monoclonal-antibody-clone-ipo-4 APT; Apoptosis Antigen; TNFRSF6; Tumor Necrosis Factor Receptor Superfamily, Member 6; Fas; APO-1 glycoproteins blots blotting antibodies antisera antiserum DNA binding anti-oncogenic apoptosis cancers p53 re-activator reactivator induces apoptotic re-activation reactivation antioncogenic immunocytochemistry immunohistochemistry IHC icc FC flow cytometry 1.484942909760
10009349 Cell Cycle Phase Determination Kit - 2007-04-20 60.504257134467 cell-cycle-phase-determination-kit assays kits measures measurements microscopy flow cytometry plate readers regulators cells transcription factors DNA proteins division proliferation induction inhibition fixation permeabilization staining sub-G1 G0 G2 S propidium iodide apoptosis cancer cell-based assay cell based assay cba 60.504257134467
10005647 Cerulenin 17397-89-6 ≥98% 2004-09-01 65.388204419889 cerulenin tumor cells fatty acid synthases FAS inhibits inhibitors inhibition cytotoxicity apoptosis cancer diet obesity D02.065.327 65.388204419889
160755 DcR2 Polyclonal Antibody - 0E-12 dcr2-polyclonal-antibody TRUNDD; TRAIL-R4 apoptosis cell death TNF DR4 DR5 DcR1 TRID TRAIL antibodies western blots blotting WB antisera antiserum immunoblotting 0E-12
10005432 DDA 25152-84-5 ≥98% 2004-07-22 14.664872928177 dda trans-2,4-Decadien-1-al; Decadienealdehyde lipoxygenases diatoms alkyls linoleic acids dihomo-gamma-linolenic dihomo-g-linolenic arachidonic dihomo-.gamma.-linolenic carcinoma Caco2 apoptosis 14.664872928177
10010706 (−)-Deguelin 522-17-8 ≥98% 2008-09-18 15.940441988951 -deguelin (-)-cis-Deguelin rotenoids flavonids cancers antiproliferative chemoprevention parkinsons diseases Akt PKB PI3K COX-2 COX2 apoptosis PI3-K 15.940441988951
10165 D-erythro-MAPP 143492-38-0 >98% 2004-02-23 22.528196513942 d-erythro-mapp (1S,2R-D-erythro-2-N-myristoylamino)-1-phenyl-1-propanol ceramides inhibitors sphingolipids HL60 HL-60 cancer cells G0/G1 G0-G1 inhibits ceramidase 22.528196513942
10009081 Didox Exclusive 69839-83-4 ≥98% ✓ 2007-01-16 19.257632202051 didox antioxidants hydroxamic acids apoptosis cancers cells polyhydroxylated aromatic ocidative injury brains HIV dementia bcl-2 19.257632202051
62237 Diphenyl-1-pyrenylphosphine 110231-30-6 ≥98% 2006-07-25 80.386255371393 diphenyl-1-pyrenylphosphine DPPP hydroperoxides oxidative stress injury fluorescence fluorescent lipids cholesterols LDL oxidation DPPPO DPPP=O atherosclerosis 80.386255371393
660990 DNA Laddering Kit - 3.107679558011 dna-laddering-kit kits assays apoptosis 3.107679558011
10006305 D-NMAPPD Exclusive 35922-06-6 ≥98% ✓ 2005-02-23 23.075789236751 d-nmappd CAY10466; (1R,2R)-B13 ceramides inhibitors cancers cells inhibits inhibition ceramidase apoptosis colorectal keratinocytes melanoma lines viability inducers induces 23.075789236751
700210 DPP (IV) Inhibitor Screening Assay Kit - 2009-05-27 101.732861418047 dpp-iv-inhibitor-screening-assay-kit Dipeptidyl exopeptidases IV DPPIV DPP4 enzymes CD26 cluster of differentiation T-cells activation antigens adenosine deaminase complexing 2 membrane-bound glycoproteins immune regulation signal transduction apoptosis kidneys small intestines placentas humans serums seminal fluids proteolytic derivatives serines X-prolines X-alanines dipeptides N-terminus N-terminal polypeptides growth factors chemokines neuropeptides vasoactive inhibitors inhibits inhibition oral antidiabetic agents glucose homeostasis glucoregulatory hormones glucose-dependent insulinotropics GIP glucagon-like peptide-1 GLP-1 gastric therapeutics Type 2 tumors cancers markers neoplasms assays kits measures measurements fluorescences fluorescent fluorogenics substrates Gly-Pro-Aminomethylcoumarin AMC 101.732861418047
10010302 DRB 53-85-0 ≥98% 2008-01-21 2.614201688497 drb Benzimidazole; NSC 401575 cancers HIV P53 apoptosis CDK7 CDK9 CTD CKI CKII adenosine inhibitors inhibits inhibition transcription RNA polymerase cell cycles adenocarcinoma transactivator tat 2.614201688497
10005190 EAF2 Polyclonal Antibody - 2004-08-12 2.012088397790 eaf2-polyclonal-antibody ELL-Associated Factor 2; U19 WB western blots blotting IHC immunohistochemistry immunoblots formalin-fixed paraffin-embedded sections apoptosis inhibits inhibitors inhibition prostate tumors testosterone suppressive supression leukemogenesis cancers endocrinology immunoblotting 2.012088397790
10022 F16 36098-33-6 ≥98% 14.918618784530 f16 apoptosis induces apoptotic mitochodrial membranes tumors inhibitors fluorescent F-16 cancer inhibits fluorescence lipophilic binding HER-1/EGFR-expressing inhibition cells breast 14.918618784530
13287 FK-866 658084-64-1 ≥98% 2009-07-21 71.532939226519 fk-866 K 22.175 nicotinamides phosphoribosyltransferase NAMPT NamPRT PBEF visfatin mononucleotides adenine dinucleotide NAD+ inhibitors inhibitis inhibition cancers apoptosis SIRT1 autophagy FK866 FK 866 K22.175 K 22175 K22175 NamPRT PBEF visfatin carcinoma cells autophagy 71.532939226519
13227 Fumonisin B2 116355-84-1 ≥98% 2009-11-11 63.157197326239 fumonisin-b2 mycotoxins fungus corn grains sphingosines inhibitors N-acyltransferase apoptosis sphingolipids hepatotoxicity nephrotoxicity fungi 63.157197326239
13355 Geldanamycin 30562-34-6 ≥98% 2010-07-29 28.262476142641 geldanamycin NSC 122750 NSC 212518 antibiotics heat shock proteins 90 Hsp90 GRP94 gp96 genes expression cells proliferation apoptosis angiogenesis c-jun adenocarcinoma cancers AP-1 steroids receptors 2,5-Cyclohexadiene-1,4-Diones 1,4-Benzoquinones 1,2-Benzoquinones p-Benzoquinones-o-Benzoquinones Benzoquinones Benzodiones Quinones 28.262476142641
10010622 Genipin 6902-77-8 ≥98% 2008-05-09 99.322569060774 genipin (+)-Genipin obesity diabeties glucose insulin mitochondria UCP2 pancreatic .beta. cells anti-inflammatory antiinflammatory angiogenesis inhibitors inhibits inhibition uncoupling proteins 2 un-coupling angiogenesis apotosis diabetes inflammation metabolism obesity 99.322569060774
10136 GPR17 (C-Term) Polyclonal Antibody - 2010-01-19 13.055138121547 gpr17-c-term-polyclonal-antibody G Protein-Coupled Receptor 17 proteins receptors antibodies western blots WB ICC signals signaling nucleotides CysLTs amino acids blotting immunoblotting FC flow cytometry immunocytochemistry cysteinyl leukotrienes 13.055138121547
10006798 GW 0742 317318-84-6 ≥98% 2007-07-25 20.800607734806 gw-0742 PPAR PPAR.beta. PPAR.delta. peroxisome proliferator activated receptor neurotoxicity agonists neuroprotection toxicity apoptosis lipids metabolism atherosclerosis endocrinology GW0742 GW-0742 20.800607734806
13127 GW 4869 6823-69-4 ≥90% 2009-06-10 48.048139963167 gw-4869 inhibitors sphingomyelin sphingomyelinase neutral acidic TNF-α ceramides cells death GW4869 gw-4869 48.048139963167
10008313 GW 610 872726-44-8 ≥98% 2006-05-10 24.835635359116 gw-610 NSC 721648 antitumors benzothiazoles inhibits inhibitors inhibition cancers antiproliferative isoflavones quercetin genistein cells MCF-7 MDA 468 NCI 60 24.835635359116
10007713 HMB-Val-Ser-Leu-VE 862891-04-1 ≥98% 2006-07-20 79.043204419889 hmb-val-ser-leu-ve 26S protease 20S ubiquitin-proteasomes pathway proteolysis proteins regulated degradation tripeptides C-terminal vinyl esters inhibits inhibition inhibitors trypsin tryptic chytotryptic cells permeable in vitro 79.043204419889
11512 HMGB1 Monoclonal Antibody (Clone IMG19N10B7) New - 2012-01-16 131.388888888888 hmgb1-monoclonal-antibody-clone-img19n10b7 High Mobility Group Protein B1; HMG1 high mobility groups proteins family DNA-binding domains inflammation mediators DNA nuclear bindings sterile infection-associated responses Toll-like receptor 4 TLR4 advanced glycation endproducts RAGE IHC immunohistochemistry Western blot blotting flow cytometry FC WB 131.388888888888
11513 HMGB1 Monoclonal Antibody (Clone IMG19N15F4) New - 2012-01-16 131.388888888888 hmgb1-monoclonal-antibody-clone-img19n15f4 HMG1; High Mobility Group Protein B1 high mobility groups proteins B1 HMGB family nuclei nucleus cytoplasm cells mediators inflammation DNA nuclear binding sterile infection-associated responses Toll-like receptors 4 TLR4 advanced glycation endproducts RAGE WB Western blots blotting flows cytometry FC immunohistochemistry IHC 131.388888888888
13782 I2PP2A/SET Polyclonal Antibody - 2010-05-10 0.552486187845 i2pp2a-set-polyclonal-antibody Phosphatase 2A Inhibitor; Template-Activating Factor I; Inhibitor of granzyme A-activated DNase; PHAPII antibodies WB western blots blotting immunoblotting histones INHAT1 INHAT 1 coactivators transcription cells TAF1α TAF 1α TAF1β TAF 1β SETs INHAT-1 protein SET SET/I2PP2A TAF-1 TAF 1 TAF1 TAF-1beta TAF-1.beta. IGAAD 0.552486187845
10008207 IGFBP5 Polyclonal Antibody - 2007-07-19 18.782697974217 igfbp5-polyclonal-antibody IGF-Binding Protein 5; IBP-5; Insulin-like Growth Factor Binding Protein 5 IGF-1 cell growth differentiation apoptosis receptors kidney heart placenta skeletal cancers amino acids neuroblastoma mammary glands antibodies wb western blots immunocytochemistry IGF1 IGFBP-5 endocrinology blotting immunoblotting 18.782697974217
13323 IM-54 861891-50-1 ≥95% 2009-10-14 2.769281767956 im-54 inhibitors necrosis necrotic cells death peroxide HL-60 leukemia apoptosis PKC S6K1 protein kinases C S6 1 indolymaleimide 2.769281767956
13925 IκBα (cleavage specific) Monoclonal Antibody (Clone 5D1623) - 2010-09-29 10.997200736648 i-b-cleavage-specific-monoclonal-antibody-clone-5d1623 antibodies IκBα IkBa IκBa IkBα IκB-α IκB α intracellular immunoblotting NF-κB NFκB NF κB slienced slience inhibitory inhibits inhibition inhibitor proteins asutoregulated auto-regulated auto regulated regulates phosphorylated kinase complex IKK IKK1 IKK2 IKK3 IKK-1 IKK-2 IKK-3 1 2 3 IKK1/a IKK1-a IKK1a IKK2/b IKK2-b IKK2b IKK3/g IKK3-g IKK3g degradation phosphorylation dimers translocates nucleus genes target cleaved caspases caspase-3 3 apoptosis amino-terminal amino terminals truncated DN-IκBα DNIκBα DN ΔN-IκBα ΔN .DELTA.N DELTAN .DELTA.N-IκBα DELTAN-IκBα DELTA-N .DELTA.-N degradation inducers dominant inhibitory molecule suppresses activity inflammation 10.997200736648
10009172 JC-1 Mitochondrial Membrane Potential Assay Kit - 2007-04-12 200.206973901921 jc-1-mitochondrial-membrane-potential-assay-kit apoptosis cells mitochondria caspases cytochrome C electrons transport transmembranes Dym DELTApsim .DELTA..psi.m fluorscence fluorescent cationic dyes rhodamine-123 Rh123 DiOC6 cytofluorimetric lipophilic tetrachloro-1,1',3,3'-tetraethylbenzimidazoylcarbocyanine iodide green red J-aggregates monomeric assays kits measures measurements microscopy flow cytometry plate readers fluorometric cancer JC1 cell-based assays cell based assay cba JC 1 200.206973901921
10641 JGB1741 Exclusive 1256375-38-8 ≥98% ✓ 2011-06-20 17.711065509076 jgb1741 ILS-JGB-1741 inhibitors SIRT1 breasts cancers cells proliferation apoptosis p53 histones acetylation genes energy homeostasis regulation deacetylases sirtuins NAD+ inhibits inhibition SIRT2 SIRT3 ILS JGB 1,741 1741 SIRTs JGB-1741 JGB-1,741 17.711065509076
70980 Lactacystin 133343-34-7 >98% 172.239149171270 lactacystin selective inhibitors neuroblastoma pleiotropic neurites 20S proteasomes inhibits streptomyces cells Neuro2A apoptosis inhibition death 172.239149171270
10008882 LDH Cytotoxicity Assay Kit - 2006-12-15 268.896420652618 ldh-cytotoxicity-assay-kit Lactate Dehydrogenase Cytotoxicity Assay Kit cells death apoptosis necrosis measuring measurement cystolic enzymes cells membranes integrity cancer cell-based assays cell based assay cba 268.896420652618
13776 Mammalian STE-20-Like Kinase 1 Polyclonal Antibody - 2010-04-28 0.826657458563 mammalian-ste-20-like-kinase-1-polyclonal-antibody STK4; KRS2; MST-1 antibodies western blots blotting immunoblotting WB MST1 STE 20 STE20 KRS-2 KRS 2 STK-2 STK terminal terminus NES nuclear export signals proteins apoptosis epigenetics 0.826657458563
13320 MCI-186 89-25-8 ≥98% 2010-07-15 26.090883977899 mci-186 NSC 2629; Edaravone free radical scavengers inhibitors inhibits inhibition ischemia-reperfusion injury transplants infections traumatic brain injury injuries Ketoquinolines Oxoquinolines Quinolinones Quinolones strokes reactive oxygen species apoptosis Norantipyrine Norphenazone Radicut 206195-95-1 115566-83-1 72134-66-8 62495-97-0 52224-17-6 12235-58-4 methylphenylpyrazolone NSC 26139 NSC 12 Edarabone 26.090883977899
600160 Methionine Sulfoxide Immunoblotting Kit - 2009-12-17 208.421613259668 methionine-sulfoxide-immunoblotting-kit MetO Immunoblotting Kit proteins sulfoxides oxidative modifications residues MSRs reactive oxygen species ROSs methionines oxidations reductases sulfones phagocytosis phagocytotic mitochondrias mitochondrial respirations sulfoxidations age-related diseases cellular cells IgG-containing sera Alzheimer's diseases immunoblots immunoblotting western blots blotting kits assays measures measurements detection tissues lysates semi-pure purified reducing non-reducing sample buffers SDS-PAGE rabbit serums immunizations oxidized corn MetO-DZS18 208.421613259668
10007188 Microcystin-LR 101043-37-2 >95% 2005-07-20 20.820000000000 microcystin-lr Cyanoginosin-LR proteins phosphatases inhibitors microcystins toxins hepatotoxic cyclics heptapeptides cyanobacteria poisonings humans livestock fresh water blue-green algae endemic PP-2A inhibits enzymes PP-1 serine/threonine nodularins okadaic acids 20.820000000000
13600 MK 0457 639089-54-6 ≥98% 2010-08-16 8.036187845304 mk-0457 Tozasertib; VX 680 mitosis aurora kinase inhibitors inhibits inhibition MK0457 MK-0457 MK-457 MK457 cells cycles cancers apoptosis tumor A B C MK 0457 VX-680 VX680 Piperazines 8.036187845304
600330 Multi-Parameter Apoptosis Assay Kit - 2010-08-18 97.464420435746 multi-parameter-apoptosis-assay-kit assays kits measures measurements apoptosis cells death cycles tissues homeostasis dysregulation neurodegenerative diseases ischemic damages autoimmune disorders cancers drugs discovery signaling pathways membranes phospholipids phosphatidylserines phosphatidylethanolamines leaflets bilayers externalizations residues plasma phospholipids binding proteins fluorochrome-labeled fluorochromes annexin V fluorescence microscopy flow cytometry FC plate readers TUNEL TdT-mediated dUTP Nick-End Labeling analysis ISEL in situ end labeling DNA deoxyribonucleic acids mitochondrial transmembranes tetramethylrhodamines ethyls esters TMRE lipophilics probes laddering detection fragmentation FITC-conjugated fluoresceins 97.464420435746
10008581 Myristoleic Acid methyl ester 56219-06-8 >98% 2007-04-17 0.552486187845 myristoleic-acid-methyl-ester cytotoxic Serenoa S. repens apoptosis necrosis prostate cancers cheese whey fatty acids Candida C. albicans MIC minimal inhibitory concentration in vivo esters hydrophobic 0.552486187845
10017 N-Ac-Asp-Glu-Val-Asp-CHO 184179-08-6 >98% 2004-04-29 8.839571823204 n-ac-asp-glu-val-asp-cho Ac-DEVD-CHO Valinamide caspases caspase 3 inhibitors Yama ICE3 CPP32 Apopain inhibition inhibits selective apoptosis 8.839571823204
10016 N-Ac-Tyr-Val-Ala-Asp-CHO 143313-51-3 >98% 2004-04-14 15.615607734806 n-ac-tyr-val-ala-asp-cho Ac-YVAD-CHO inhibitor inhibits apoptosis interleukins inhibition selective irreversible interleukin-1.beta.converting enzyme ICE Caspase-1-IL-1.beta. Il1beta neuroprotective cerebral ischemia alaninamides 15.615607734806
10014 N-Ac-Tyr-Val-Ala-Asp-CMK 178603-78-6 >98% 2004-04-13 27.311325966850 n-ac-tyr-val-ala-asp-cmk Ac-YVAD-CMK inhibitors inhibits interleukins neuroprotective cerebral ischemia inhibition selective irreversible interleukin-1.beta.converting enzyme ICE Caspase-1-IL-1.beth. IL1beta neuroprotective cerebral ischemia alaninamides neurochemistry chloromethyl ketones 27.311325966850
13754 NF-κB (p50) Polyclonal Antibody - 2010-04-27 11.545441988950 nf-b-p50-polyclonal-antibody NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB nuclear transcription factors DNA p65 N-terminal binding western blots blotting immunoblotting WB antibodies 11.545441988950
13756 NF-κB (p65) Monoclonal Antibody-biotin (Clone 112A1021) - 2010-02-11 22.794680347277 nf-b-p65-monoclonal-antibody-biotin-clone-112a1021 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting WB biotins biotinylated biontinylation 112A1021 clones 22.794680347277
13752 NF-κB (p65) Monoclonal Antibody (Clone 112A1021) - 2010-02-11 25.778105761641 nf-b-p65-monoclonal-antibody-clone-112a1021 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting flow cytometry FC WB immunohistochemistry IHC 25.778105761641
13751 NF-κB (p65) NLS Polyclonal Antibody - 2010-02-11 24.958658247829 nf-b-p65-nls-polyclonal-antibody Nuclear Factor-κB (p65) Nuclear Localization Signal NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB transcription factors N-terminal C-terminal terminals terminus signals tissues nuclear receptors western blots blotting immunoblotting WB immunocytochemistry ICC antibodies 24.958658247829
13757 NF-κB (p65) Polyclonal Antibody (aa 2-17) - 2010-02-11 18.005414364640 nf-b-p65-polyclonal-antibody-aa-2-17 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting WB amino acids 2 7 18.005414364640
13753 NF-κB (p65) Polyclonal Antibody (aa 538-546) - 2010-02-11 22.794680347277 nf-b-p65-polyclonal-antibody-aa-538-546 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting WB amino acids 538 546 22.794680347277
10011255 NSC 210902 51726-83-1 ≥95% 2008-09-15 4.363314917128 nsc-210902 Inhibitor inhibits inhibition CK2 kinase cell signaling apoptosis cancers NSC210902 4.363314917128
18585 (−)-Nutlin-3 - ≥98% 2008-08-06 213.659815837938 -nutlin-3 Nutlin 3a P53 cellular stress proliferation cells cycle apoptosis tumor suppressor MDM2 agents Nutlin-3 enantiomer a 213.659815837938
10009816 (+)-Nutlin-3 - ≥98% 2008-08-11 96.811767955801 -nutlin-3 Nutlin 3b p53 cellular stress proliferation cells cycle apoptosis tumer suppressor MDM2 inactive inhibitors inhibits inhibition Nutlin-3 enantiomer b 96.811767955801
10004372 (±)-Nutlin-3 548472-68-0 >98% 2004-04-06 82.894925626859 -nutlin-3 apoptosis cancers p53 inhibits inhibitors induces apoptotic re-activation reactivation antioncogenic tumors xenografts license:hoffmanlaroche Nutlin3 nutlins 82.894925626859
10011301 p38 MAPK Monoclonal Antibody (Clone 9F12) - 2008-05-22 1.869005524861 p38-mapk-monoclonal-antibody-clone-9f12 p38 Mitogen-activated Protein Kinase; p38 MAPKα serine threonine serine-threonine cell cycles development apotosis kinases stress signals cytokines gene expression western blots immunoblotting immunocytochemisty ICC WB flow cytometry signal transduction signalling signaling blotting FC 1.869005524861
10993 p53DINP1 Polyclonal Antibody New - 2011-12-19 42.585620779619 p53dinp1-polyclonal-antibody TP53INP1; SIP genes p53-dependents damage-inducible nuclear proteins apoptosis phosphorylation Ser46 p53AIP1 Western blots blotting p53 dependents WB 42.585620779619
10005291 p53 Product Pack - 2004-09-08 20.094964190710 p53-product-pack DNA binding anti-oncogenic apoptosis cancer p53 re-activators reactivators induces apoptotic re-activation reactivation antioncogenic packs 20.094964190710
10009317 PAC-1 315183-21-2 >98% 2007-07-12 17.072633517495 pac-1 Procaspase-activating Compound 1 in vitro procaspase-3 apoptosis cancers cells death drugs treatment acivators procaspases PAC1 17.072633517495
10461 Paclitaxel 33069-62-4 ≥98% 2010-08-23 24.396629834254 paclitaxel Taxol®; NSC 125973 Microtubules cancers cervical HeLa lung A549 breast MCF-7 colon HT-29 ovarian OVG-1 pancreatic PC-Sh carcinomas chemotherapy mitotic arrest apoptosis JNK BCL-2 p53 Pacific yew tree c-Jun cyclin-dependent kinases multipolar spindle formation Abraxane Capxol Mitotax Onxal QW 8184 Yewtaxan Tocosol Taxus Liberte Genexol-PM Genetaxyl EndoTAG 1 Ebetaxwl DHP 107 ABI 007 Bristol-Myers Squibb Brand of Paclitaxel Bristol-Myers Brand of Paclitaxel Paclitaxel (4 alpha)-Isomer Lemery Brand of Paclitaxel Ivax Brand of Paclitaxel Bull Brand of Paclitaxel 7-epi-Taxol 7 epi Taxol Paclitaxel NSC-125973 NSC 125973 Bris Taxol NSC125973 Taxol A Anzatax Praxel Paxene Taxol Onxol 24.396629834254
10007946 Palmitoyl Sphingomyelin 6254-89-3 ≥98% 2010-12-06 41.825856353590 palmitoyl-sphingomyelin N-palmitoyl-D-erythro-sphingosylphosphorylcholine membranes lipids sphingosines eggs brains cholesterol rafts ceramides sphingolipids apoptosis 16:0 SM (d18:1/16:0) hexadecanoyl sphingomyelin N-(hexadecanoyl)-sphing-4-enine-1-phosphocholine PCs 41.825856353590
10010518 PD 146176 4079-26-9 ≥98% 2009-02-25 31.652648041431 pd-146176 NSC 168807 atherosclerosis 15-LOs 15-lipoxygenases oxidant injury injuries apoptosis amyloid β proteins inhibitors inhibits inhibitions Alzheimers disease oxidative stress pd146176 31.652648041431
10012431 PD 184161 Exclusive 212631-67-9 ≥98% ✓ 2009-06-09 35.417814273821 pd-184161 MEK inhibitors MAP kinase ERK signaling cancer MEK 1/2 inhibition inhibited ERK 1/2 potent selective pd184161 35.417814273821
10007191 PH Domain Leucine-rich Repeat Protein Phosphatase 1 Polyclonal Antibody - 2006-01-04 3.916111878452 ph-domain-leucine-rich-repeat-protein-phosphatase-1-polyclonal-antibody Suprachiasmatic Nucleus Circadian Oscillatory Protein; SCOP; PLEKHE1 Protein; PHLPP1; KIAA0606 Protein proteins diseases antibodies antisera antiserum western blots blotting immunocytochemistry ICC immunohistochemistry IHC cancers WB immunoblotting PH Domain Leucine-rich Repeat Protein Phosphatase Polyclonal Antibody 3.916111878452
13326 Pifithrin-α 63208-82-2 ≥95% 2009-07-16 31.221263812155 pifithrin p53 apoptosis DNA damage cyclin D1 C8 cells HUVECs endothelial cells dependent independent inactivator 31.221263812155
10748 Pifithrin-μ 64984-31-2 ≥98% 2011-06-20 17.587941988950 pifithrin PFT-μ; 2-Phenylethynesulfonamide p53 apoptosis Bcl-xL Bcl-2 mitochondria inhibitors nutlin heat shock proteins 70 HSP70 PES PAS pifithrin-mu pifithrin mu PFTμ PFTu 2-phenylacetylenylsulfonamide 2-phenylacetylenesulfonamide BclxL Bc12 17.587941988950
9000185 Prostaglandin A2 methyl ester Exclusive 31753-19-2 ≥98% ✓ 2010-11-08 1.213419275629 prostaglandin-a2-methyl-ester PGA2 methyl ester; Medullin methyl ester hypertension cancers lipophilic analogs PGA2 prostaglandins 1.213419275629
13527 Pseudolaric Acid B 82508-31-4 ≥98% 2009-12-04 9.385994475137 pseudolaric-acid-b PAB Pseudolarix kaempferi traditional Chinese fungal fungus infections cancers apoptosis angiogenesis tumors inhibits inhibitors inhibition P. therapy apoptosis cells 9.385994475137
10005059 PTEN Polyclonal Antibody - 2005-05-04 4.439481512962 pten-polyclonal-antibody TEP1; Phosphoinositide 3-phosphatase; MMAC1; Phosphatase and Tensin Homolog on Chromosome 10 proteins antibodies antisera antiserum wb western blots blotting IHC immunohistochemistry dephosphorylates lipids AKT phosphatidylinositols triphosphates PIP3 tissues acids regulates cells division migrations apoptosis mutations cancers melanomas prostates carcinomas A431 HEK293 signals transductions cancers endocrinology immunoblotting 4.439481512962
10009594 Pyocyanin 85-66-5 >98% 2007-07-12 32.295635359116 pyocyanin Pyocyanine; Sanazin; Sanasin Pseudonomas aeruginosa phenazine metabolite neutrophil apoptosis Cystic fibrosis 32.295635359116
301785 RICK Blocking Peptide - 7.225524861878 rick-blocking-peptide apoptosis kinases CARD domains RIP-like interacting CLARP Fas western blots blotting WB controls peptides 7.225524861878
160785 RICK Polyclonal Antibody - 8.515303867402 rick-polyclonal-antibody Ripk2; Rip2; CARDIAK apoptosis antibodies kinase CARD domains RIP Fas western blots blotting WB antisera antiserum RIP-2 cancers immunoblotting CCK CCKs CCCK 8.515303867402
10006426 RITA 213261-59-7 >98% 2006-01-11 28.073474524248 rita NSC 652287; 2,5-bis(5-hydroxymethyl-2-thienyl) Furan HDM-2 human double minute-2 MDM-2 mouse murine negative regulator p53 proteasomal degradation tumors cancers apoptosis cells reactivation molecules inhibitors wild-type DNA-protein human renal SCID mice HCT116 A-498 xenografts nude HDM2 HDM-2 MDM2 28.073474524248
13697 (R)-MG132 Exclusive 1211877-36-9 ≥98% ✓ 2010-06-22 93.183756906077 -r-mg132 ubiquitin proteasomes inhibitors proteolytic degradation inflammation cells cycle regulation cancers NF-κB apoptosis inhibition inhibited 93.183756906077
13628 Salidroside 10338-51-9 ≥97% 2010-05-28 12.325948434623 salidroside Rhodioloside glycosides plants Rhodiola Chinese medicine memory infections inflammation cancers diabetes fatigue apoptosis Glucosides 12.325948434623
10010401 SIRT1 Direct Fluorescent Screening Assay Kit - 2008-02-26 53.919013812155 sirt1-direct-fluorescent-screening-assay-kit SIRT 1 assays kits measures sirtuins trichostatins A-intensive lysyl-deacetylases class III HDACs human homologs yeast SIR2 silent information regulators 2 tumors cancers suppressors inhibits inhitors inhibition apoptosis screening fluorescence activators fluorescent fluorometric 53.919013812155
10010991 SIRT1 FRET-Based Screening Assay Kit - 2008-02-19 26.453930939226 sirt1-fret-based-screening-assay-kit SIRT 1 assays kits measures sirtuins trichostatins A-intensive lysyl-deacetylases class III HDACs human homologs yeast SIR2 silent information regulators 2 tumors cancers suppressors inhibits inhitors inhibition apoptosis screening fluorescence activators fluorescent fluorometric 26.453930939226
10838 SMAD4 Polyclonal Antibody - 2011-05-05 1.154475138121 smad4-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-4 SMAD 4 antibodies serum IHC immunohistochemistry TGF-β TGFβ cancers 1.154475138121
10839 SMAD6 Polyclonal Antibody - 2011-05-02 0.422541436464 smad6-polyclonal-antibody WBs western blots immunoblotting SMADs MAD SMAD-6 SMAD 6 antibodies serum IHC immunohistochemistry TGF-β TGFβ Tcells intracellular proteins signaling serine threonine apoptosis bones cancers genes signal transduction 0.422541436464
10012628 (S)-MG132 133407-82-6 ≥98% 2009-02-18 192.178839779005 -s-mg132 Z-Leu-Leu-Leu-CHO ubiquitin proteasome inhibitors inhibits inhibition proteolytic degradation inflammation cell cycle regulation cancers NF-kB NFkB apoptosis NF-κB mg 132 mg-132 2-LLL-CHO 192.178839779005
10010466 SP 600125 129-56-6 ≥98% 2009-01-07 11.958232044199 sp-600125 1PMV; Pyrazolanthrone; NSC 75890 c-Jun cJun JNKs inhibitors inhibits inhibition reversible cell-permeable cells COX-2 COX2 MAP kinase MAPK genes expressions apoptosis autophagy differentiation IL-10 IL10 TNF-α TNFα IFN-γ IFNγ T-cells Tcells HeLa sp600125 11.958232044199
10008012 SPD-304 Exclusive 869998-49-2 >98% ✓ 2006-08-07 19.841215469613 spd-304 TNF-.alpha. TNF.alpha. signal transduction inflammation small-molecule inhibitor cytokine apoptosis NF-kB AP-1 inhibitor antagonist SPD304 SPD 304 CAY10500 CAY 10500 SPD00000304 SPD 00000304 19.841215469613
700330 Sphingomyelinase Inhibitor Screening Assay Kit - 2010-02-09 37.411236516705 sphingomyelinase-inhibitor-screening-assay-kit SMase assays kits measures measuring measurementsphingomyelinases SMases hydrolases enzymes sphingolipids metabolisms DNase I superfamily phosphocholines ceramides cellular cells stress pathophysiological lysosomal digestion ceramide-mediated signal transductions cytokine-induced apoptosis differentiation immune inflammatory lipoproteins aggregation vessels atherogenesis intracellular trafficking acidic neutral proliferation depressive disorders neurodegenerative disorders strokes Alzheimer's dementia diseases therapeutics cleavage conjugates free thiols 37.411236516705
62570 Sphingosine-1-Phosphate 26993-30-6 >98% 138.615745856353 sphingosine-1-phosphate S1P; Sphingosine-1-Phosphoric Acid sphingosines phosphates ceramides apoptosis Sphingosine-1-phosphoric acids cells death kinases sphingomyelin growth calcium 138.615745856353
10012201 Sphingosine Kinase 1 Polyclonal FITC Antibody Exclusive - ✓ 2008-06-06 7.574102209944 sphingosine-kinase-1-polyclonal-fitc-antibody SPHK 1 SPHK-1 metabolism sphingolipids phosphorylation sphingosine-1-phosphate cell proliferation death immunofluorescence IF flow cytometry FC western blots WB SPHKs blotting immunoblotting 7.574102209944
10846 STAT1α/β Polyclonal Antibody - 2011-05-31 0E-12 stat1-polyclonal-antibody Signal Transducers and Activators of Transcriptions transcriptions factors genes expressions growth TNFR-1 TNFR1 apoptosis WBs western blots blotting immunoblotting STAT1alpha/beta STAT1 alpha/beta signaling signalling STAT 1 STAT-1 STAT1a/b 0E-12
10847 STAT2 Polyclonal Antibody - 2011-05-31 0E-12 stat2-polyclonal-antibody Signal Transducers and Activators of Transcriptions transcription factors genes expressions growth TNFR-1 TNFR1 apoptosis WBs western blots blotting immunoblotting STAT-2 STAT 2 signaling signalling 0E-12
10861 STAT3 (Phospho-Tyr705) Polyclonal Antibody - 2011-05-31 0E-12 stat3-phospho-tyr705-polyclonal-antibody Signal Transducers and Activators of Transcriptions transcription factors genes expressions growth TNFR-1 TNFR1 apoptosis WBs western blots blotting immunoblotting STAT-3 STAT 3 signaling signalling 0E-12
10856 STAT5β Polyclonal Antibody - 2011-05-31 0E-12 stat5-polyclonal-antibody Signal Transducers and Activators of Transcriptions transcription factors genes expressions growth TNFR-1 TNFR1 apoptosis WBs western blots blotting immunoblotting STAT5beta STAT5 signaling signalling STAT 5 STAT-5 0E-12
10931 STAT6 Polyclonal Antibody - 2011-07-13 0E-12 stat6-polyclonal-antibody Signal Transducers and Activators of Transcription 6; IL-4 STAT transcription factors genes expressions growth TNFR-1 TNFR1 apoptosis WBs western blots blotting immunoblotting STAT-6 STAT 6 signaling signalling 0E-12
10008196 Stearic Acid ethyl ester 111-61-5 >98% 2006-05-30 1.107509562260 stearic-acid-ethyl-ester Ethyl Stearate; Ethyl Octadecanoate; NSC 8919 esters saturated acids animal vegetable fats lipid soluble ethanol metabolites cells cycle apoptosis HepG2 excessive alcohol hair 1.107509562260
70302 tetramethyl Nordihydroguaiaretic Acid Exclusive 24150-24-1 ≥98% ✓ 2008-09-24 5.184364640883 tetramethyl-nordihydroguaiaretic-acid tetramethyl NDGA; TMNDGA; Tetrameprocol; M4N; EM-1421 tumors inhibitor inhibits inhibition cancers NDGAs survivin apoptosis Cdc2 HIV growing growth glioma brains antitumor organic melonomas 5.184364640883
10009813 thio-Miltefosine - >98% 2007-08-13 10.919558011049 thio-miltefosine analogs inhibitors inhibit inhibition CTP phosphocholine cytidylyl transerases antimetastatic antiproliferatives ceramides apoptosis antiprotazoal thiomiltefosine sulfurs thios 10.919558011049
10038 TMS 24144-92-1 >98% 54.550773480662 tms 2,3',4,5'-Tetramethoxystilbene cytochromes inhibitors tetramethoxystilbene antimutagenesis CYP450-1B1 inhibits selective selectivity apoptosis cell growth 54.550773480662
11105 TNF Receptor-Associated Protein 1 (human recombinant) New - ≥95% 2011-11-29 19.536402701043 tnf-receptor-associated-protein-1-human-recombinant Hsp90L; Hsp75; TRAP1; Mitochondrial Heat Shock Protein 75 kDa metabolism insulin non-insulin-dependent (type 2) diabetes mellitus glucose kinases tumors necrosis factor type 1 receptors-associated proteins TNFR-associated protein 1 ATP mitochondrial HSP90 heat shock ATPase cancers cardiomyocytes geldanamycin SNX-0723 SNX0723 SNX 0723 TNFR1 19.536402701043
13340 TPEN 16858-02-9 ≥95% 2010-08-03 17.327219152855 tpen TPEDA zinc apoptosis hypoxic pulmonary vasoconstrictions cells proliferation differentiation caspases transition metals chelators cancers intracellular extracellular intracellular extra- intra- extra cellular ions concentrations vasoconstrictiors 17.327219152855
10855 TRAF2 Monoclonal Antibody (Clone 33A1293) - 2011-05-06 0E-12 traf2-monoclonal-antibody-clone-33a1293 TRAF 2 TRAF-2 WBs western blots TNF tumors necrosis antibodies signal transduction proteins blotting immunoblotting 0E-12
10872 TRAF3 Polyclonal Antibody - 2011-05-26 1.445104972375 traf3-polyclonal-antibody TRAF 3 TRAF-3 WBs western blots TNF tumors necrosis antibodies signal transduction proteins blotting immunoblotting 1.445104972375
10873 TRAF5 Monoclonal Antibody (Clone 55A219) - 2011-05-26 1.445104972375 traf5-monoclonal-antibody-clone-55a219 TRAF 5 TRAF-5 WBs western blots TNF tumors necrosis antibodies signal transduction proteins blotting immunoblotting 1.445104972375
10894 TRAF6BP Polyclonal Antibody - 2011-05-26 1.445104972375 traf6bp-polyclonal-antibody T6BP; TAX1BP1; TRAF6 Binding Protein; TAX1-binding protein TRAF 6BP TRAF-6BP WBs western blots TNF tumors necrosis antibodies signal transduction proteins blotting immunoblotting 1.445104972375
10874 TRAF6 Polyclonal Antibody - 2011-05-26 1.445104972375 traf6-polyclonal-antibody TNF Receptor-Associated Factor 6 TRAF 6 TRAF-6 WBs western blots TNF tumors necrosis antibodies signal transduction proteins blotting immunoblotting 1.445104972375
160750 TRAIL Polyclonal Antibody - 0E-12 trail-polyclonal-antibody Apo-2L apoptosis cell death TNF DR4 DR5 NF-.kappa.B NF-kappab NF-kappab antisera antiserum antibodies WB western blots blotting cancers immunoblotting 0E-12
9000784 (−)-trans-C75 Exclusive 1234694-22-4 ≥98% ✓ 2011-07-20 11.679447513812 -trans-c75 (2S,3R)-C75 trans C75 transC75 inhibitors inhibits inhibition fatty acids synthases FAS apoptosis cancers obesity C-75 apoptosis 11.679447513812
9000783 (+)-trans-C75 Exclusive 1234694-20-2 ≥98% ✓ 2011-07-20 11.679447513812 -trans-c75 (2R,3S)-C75 transC75 trans C75 fatty acids synthases FAS apoptosis cancers obesity inhibitors inhibits inhibition C-75 11.679447513812
13791 TRF2 Polyclonal Antibody - 2010-06-24 0E-12 trf2-polyclonal-antibody TTAGGG Repeat Binding Factor 2; TRBF2; Telomeric Repeat Binding Factor 2; TERF2 antibodies proteins TRF-2 TRF 2 factors repeat DNA binding cells apoptosis western blots blotting immunoblotting telomere WB ICC IP ChIP IF immunoprecipitation immunofluorescence immunocytochemistry cancers apoptosis 0E-12
10009083 Trimidox Exclusive 95933-74-7 >98% ✓ 2008-02-13 5.938674033149 trimidox VF 233 apoptosis ribonucleotide reductases cells cycles cancers dNTP HIV caspase DNA synthesis chemotherapy dGTP HL-60 5.938674033149
10011124 Trimidox (hydrochloride) Exclusive - >98% ✓ 2008-06-10 5.938674033149 trimidox-hydrochloride CF 233 (hydrochloride) apoptosis ribonucleotides reductases cells cycles cancers dNTP HIV caspases DNA synthesis chemotherapy dGTP HL-60 HCls 5.938674033149
10010591 Wortmannin 19545-26-7 ≥98% 2008-11-21 43.700611040279 wortmannin KY 12420 phosphoinositide 3-kinase PI3K cells growth differentiations cancers motility inhibitors inhibits inhibition irreversible polo-like kinases PLK1 PLK3 mTOR DNA-PK DNAPK PL4K MLCK p38 MAPK 43.700611040279
10008883 WST-1 Cell Proliferation Assay Kit - 2006-09-07 68.871443443518 wst-1-cell-proliferation-assay-kit assays cells proliferation induction inhibitors inhibition inhibits growth factors signaling signalling molecules cycles regulatory factors cytokines mitogens drugs microtiter plates in vitro enzymes enzymatic cleavage tertrazolium salts formazan cellular mitochondrial dehydrogenases screen kits measures measurements cancers cell-based assay cell based assay cba 68.871443443518
10010199 WST-8 Cell Proliferation Assay Kit - 2007-09-11 77.795786831703 wst-8-cell-proliferation-assay-kit assays cells proliferation induction inhibitors inhibition inhibits growth factors signaling signalling molecules cycles regulatory factors cytokines mitogens drugs microwell plates in vitro enzymes enzymatic cleavage tertrazolium salts formazan cellular mitochondrial dehydrogenases screen kits measures measurements special:quarterly specialdiscount:50 specialstart:2007-12-01 specialend:2008-02-29 cell-based assay cell based assay cba 77.795786831703
10010200 XTT Cell Proliferation Assay Kit - 2007-09-11 57.722205716685 xtt-cell-proliferation-assay-kit assays cells proliferation induction inhibitors inhibition inhibits growth factors signaling signalling molecules cycles regulatory factors cytokines mitogens drugs microtiter plates in vitro enzymes enzymatic cleavage tertrazolium salts formazan cellular mitochondrial dehydrogenases screen kits measures measurements special:quarterly specialdiscount:50 specialstart:2007-12-01 specialend:2008-02-29 cell-based assay cell based assay cba 57.722205716685
11168 (−)-YK-4-279 New - ≥98% 2011-12-19 62.516298342541 -yk-4-279 ES-FLI1 oncogenes Ewing's sarcomas RNA helicases tumors cancers inhibitors apoptosis ETS transcription factors ERG ETV1 prostate fusion proteins diseases YK4279 YK 4279 growth xenografts cells chemotherapy resistant Ewings ESFLI1 ES FLI1 prostate 62.516298342541
11167 (+)-YK-4-279 New 1261038-93-0 ≥98% 2011-12-16 60.849631675875 -yk-4-279 ES-FLI1 oncogenes Ewing's sarcomas RNA helicases tumors cancers inhibitors apoptosis ETS transcription factors ERG ETV1 prostate YK4279 YK 4279 fusion proteins diseases growth orthotopic xenografts cells chemotherapy resistant Ewings EWS-FLI1 reduces in vitro in vivo family prostate cancers enantiomers EWSFLI1 EWS FLI1 60.849631675875
13661 YK-4-279 1037184-44-3 ≥98% 2010-02-05 44.477041129527 yk-4-279 ES-FLI1 oncogene Ewing's sarcomas RNA helicases A RHAs tumors cancers inhibitors apoptosis inhibition inhibited Ewings YK 4-279 YK4279 YK 4279 YK 4 279 Pentaacetic Acid, Diethylenetriamine Acid, Diethylenetriamine Pentaacetic Diethylenetriamine Pentaacetic Acid calcium trisodium pentetate Pentetic Acid DTPA pentacin penthanil 44.477041129527
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