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Research Area · Cancer

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Item Number Product Sizes & Pricing CAS Purity Image Exclusive Introduction Date Mojo Plain Text Name Synonyms Keywords Interest
71220 1,4-DPCA 331830-20-7 ≥98% 2007-06-22 39.309127276448 1-4-dpca 1,4-dihydrophenonthrolin-4-one-3-Carboxylic acid HIF-1.alpha. normoxic HIF-.alpha. prolyl HIF-PH inhibitors collagen fibrosis 4-hydroxylase normoxia hypoxic hypoxia-inducible factor HIF1.alpha. HIF1alpha HIFPH inhibition inhibits 39.309127276448
12700 15-deoxy-Δ12,14-Prostaglandin D2 85235-11-6 ≥95% 108.501270718232 15-deoxy-12-14-prostaglandin-d2 15-deoxy-Δ12,14-PGD2 PPARs prostaglandins peroxisome proliferator-activated receptors 15-deoxy-DELTA12,14-PGD2 15-deoxy-.DELTA.12,14-PGD2 15-deoxy-d12,14-PGD2 leukemia cells cancer 15d-pgd2 108.501270718232
10009742 15-hydroxy Prostaglandin Dehydrogenase Western Ready Control - ≥90% by SDS-PAGE 2007-04-03 51.058484609313 15-hydroxy-prostaglandin-dehydrogenase-western-ready-control 15-hydroxy PGDH blotting blots western WB oxidation enzymes tumors suppression cells proliferation 51.058484609313
10011263 15-Lipoxygenase-2 (human recombinant) - >95% 2008-03-25 38.109361571516 15-lipoxygenase-2-human-recombinant 15-LO-2; 15-LOX-2 arachidonic acids recombinant proteins 15-HETE 15-HpETE active 38.109361571516
10011500 15-Lipoxygenase-2 Western Ready Control - 2008-06-25 18.916639879458 15-lipoxygenase-2-western-ready-control 15-LO-2; 15-LOX-2 WBs lipoxygenases 15LOX 15LO arachidonic acid AA 15(S)-hydroxyeicosatetraenoic acid 15(S)-HETE 15S-HETE western blots immunoblotting blotting 18.916639879458
34720 15(S)-HETE 54845-95-3 ≥98% 36.312494080505 15-s-hete soybean 15-LOs asthma airway 15-lipoxygenases monohydroxy fatty acids 15S-HETES 15-HETES arachidonic 15(S)-HETEs 15(S)HETEs potato polyunsaturated 15HETEs 36.312494080505
334720 15(S)-HETE-d8 84807-87-4 ≥99% deuterated forms (d1-d8) 33.119594843463 15-s-hete-d8 GC/MS deuterium isotopes 15-HETE-d8 standards 15S-HETE-d8 15(S)HETE-d8 deuterated GC-MS LC/MS LC-MS 15-HETEs 15(S)-HETEs 15S-HETEs 15(S)HETEs hydroxy fatty acids mass spectrometry 15HETE 33.119594843463
534721 15(S)-HETE EIA Kit - 73.321731123388 15-s-hete-eia-kit 15(S)-HETE ELISA Kit solid plates 15(S)-HETEs 15S-HETEs measures kits eias enzyme immunoassays ELISAs 15(S)HETEs 15HETEs assays 73.321731123388
10007251 15(S)-HETE Lipid Maps MS Standard 54845-95-3 ≥98% 2009-02-17 16.312885677858 15-s-hete-lipid-maps-ms-standard soybean 15-LOs asthma airway 15-lipoxygenases monohydroxy fatty acids 15S-HETES 15-HETES arachidonic 15(S)-HETEs 15(S)HETEs potato polyunsaturated MS mass spectrometry standards 15HETE 16.312885677858
11039 17-AAG New 75747-14-7 ≥98% 2012-03-21 31.777777777778 17-aag KOS 953; NSC 330507; Tanespimycin; CP 127374; BMS 722782 17AAG 17 AAG inhibitors inhibits inhibition heat shock proteins Hsp90 geldanamycin cancers breasts HER2 hepatotoxicity analogs tumors prostate cells apoptosis NSC330507 NSC-330507 BMS722782 BMS-722782 CP127374 CP-127374 KOS-953 KOS953 31.777777777778
11036 17-DMAG New 467214-20-6 ≥98% 2012-03-14 20.000000000000 17-dmag NSC 707545; KOS-1022; Alvespimycin inhibitors inhibits inhibition heat shock proteins Hsp90 geldanamycin cancers inflammation renal failure tissues tumors NF-κB mice mouse diabetes KOS1022 KOS 1022 NSC-707545 NSC707545 20.000000000000
10009799 17(S)-HDoHE - ≥98% 2007-03-12 13.789244935543 17-s-hdohe 17(S)-hydroxy Docosahexaenoic Acid resolvins 17-HDHA docosahexaenoic acid COX-2 .omega.-3 w-3 aspirin hydroxylated metabolites oxygenation aspirin-inhibited cyclooxygenase-2 polyhydroxylated TNFa TNF.alpha. IL-1b IL-1.beta. glioma cells COX2 PGHS2 PGHS-2 prostaglandin synthases neurochemistry 17(s)-hdohe 13.789244935543
13812 17β-hydroxy Wortmannin Exclusive - ≥98% ✓ 2010-05-18 14.370954914398 17-hydroxy-wortmannin phosphoinositide 3-kinase PI3K mTOR inhibitors inhibits inhibition inhibitory cancers 17-hydroxywortmannins 17-hydroxy wortmannins hydroxywortmannins PI3-K HWT phosphatidylinositol 14.370954914398
10954 1-NA-PP1 221243-82-9 ≥98% 2011-09-30 56.814033149171 1-na-pp1 1-Naphthyl-PP1; PP1 Analog inhibitors inhibits inhibition kinases mutated analogs sensitive v-Src vSrc c-Fyn cFyn CDK2 c-Abl cAbl mammalian yeast 1NMPP1 1NA-PP1 cells permeable tyrosine cell-permeable AS Src-family Src I338G v-Src-AS1 56.814033149171
10010093 1-Oleoyl Lysophosphatidic Acid Exclusive 65528-98-5 >95% ✓ 2007-08-29 30.284604051565 1-oleoyl-lysophosphatidic-acid Oleoyl-sn-3-Glycerophosphate; 1-Oleoyl LPA LPAS 1-oleoyl-LPAS agonists GPCR G-proteins cell proliferation smooth muscle contraction platelet aggregation reurite retraction 30.284604051565
10010094 1-Palmitoyl Lysophosphatidic Acid 22002-85-3 ≥98% 2010-11-29 9.517127071823 1-palmitoyl-lysophosphatidic-acid 1-Palmitoyl LPA (free acid) GPCR G-proteins cells proliferation smooth muscles contractions platelets aggregation 9.517127071823
10010290 1-Palmitoyl Lysophosphatidic Acid (sodium salt) Exclusive - >98% ✓ 2007-09-05 16.371922651933 1-palmitoyl-lysophosphatidic-acid-sodium-salt 1-Palmitoyl LPA 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphate monopalmitoylphosphatidic acid MPPA LPAS GPCRs biological responses 16.371922651933
10009962 2-(14,15-Epoxyeicosatrienoyl) Glycerol 848667-56-1 ≥95% 2008-04-03 39.494825046040 2-14-15-epoxyeicosatrienoyl-glycerol 2-14,15-EG 2-AG CYP450 metabolism mitogens cancers kidneys endocannabinoids cannabinoids cbs synthetic 39.494825046040
13373 2',3',5'-triacetyl-5-Azacytidine 10302-78-0 ≥95% 2010-08-05 6.038779811465 2-3-5-triacetyl-5-azacytidine inhibitors inhibits inhibition DNA methyltransferases epigenetics methylation myelodysplastic syndromes cancers prodrugs 5-azacytidine 5-azacitidine azacytidine azacitidine rapid absorption o rally 6.038779811465
10005229 2,3-DCPE (hydrochloride) - ≥98% 2006-09-15 12.431169429097 2-3-dcpe-hydrochloride apoptosis Bcl-XL p21 ERK cancers cells cycles proapoptotic in vitro S-phase arrest upregulate activates activation 12.431169429097
71200 2,4-DPD 41438-38-4 ≥98% 46.522112952732 2-4-dpd 2,4-Diethylpyridine dicarboxylate inhibits inhibition inhibitors proline-hydroxylases P564 HIF-PH HIF-1alpha HIF-1.alpha. alpha-keto glutarate .alpha.-keto a-keto cancer 46.522112952732
10008887 (+)-2,5-epi Goniothalesdiol Exclusive - ≥98% ✓ 2009-03-02 0E-12 -2-5-epi-goniothalesdiol tetrahydrofuran cytotoxic pesticide anticancers drugs antitumor styryl lactone 0E-12
11097 25-hydroxy Cholesterol New 2140-46-7 ≥98% 2012-02-08 1.138270922856 25-hydroxy-cholesterol 16505-96-7 oxysterol cholesterol SREBP sterols regulatory elements binding proteins atherosclerosis anticancer apoptosis immunosuppressive Bcl-2 caspases atherosclerosis antitumor tumors LXR-RXR ligands T cells macrophages 1.138270922856
11099 25-hydroxy Cholesterol-d6 New 88247-69-2 ≥99% deuterated forms (d1-d6) 2012-01-27 0.241974626560 25-hydroxy-cholesterol-d6 deuterated deuterium GC/MS GC-MS LC/MS LC-MS mass spectrometry MS 16505-96-7 oxysterol cholesterol SREBP sterols regulatory elements binding proteins atherosclerosis anticancer apoptosis immunosuppressive Bcl-2 caspases atherosclerosis antitumor tumors LXR-RXR ligands T cells macrophages 0.241974626560
13019 2-Hydroxyestradiol 362-05-0 ≥95% 2009-01-20 19.085322283609 2-hydroxyestradiol 2-HE2; NSC 61711 estradiols steroids metabolism catechol-O-methyltransferase COMT pre-eclampsia preeclampsia angiogenesis cancers anticancer HIF-1α HIF1α 19.085322283609
13021 2-Methoxyestradiol 362-07-2 ≥98% 2009-01-06 80.715256511444 2-methoxyestradiol Panzem; NSC 659853; 2-ME2; 2-Hydroxyestradiol 2-methyl ether estradiol steroids catechol-O-methyltransferase COMT pre-eclampsia preeclampsia angiogenesis cancers anticaner HIF-1α HIF1α 2-methoxyestradiol 80.715256511444
582261 2-Methoxyestradiol EIA Kit - 2010-12-09 176.477409453652 2-methoxyestradiol-eia-kit 2-Hydroxyestradiol 2-methyl ester; 2-ME2 metabolites estradiols antitumors antiangiogenics breast prostate cancers cardioprotective cytochromes P450 CYP450 P450-dependent hydroxylation 17β-estradiols 2-position O-methylation catechol-O-methyltransferases pre-eclampsia plasma urine urinary markers therapeutics supplements estrogen receptors pregnancy ELISAs EIAs enzymes immunoassays kits competitive quantification measures measurements sample matrices 176.477409453652
11046 2-NBDG 186689-07-6 ≥98% (mixture of α and β) 2011-10-07 93.043431031821 2-nbdg NBD-Glucose fluorescence fluorescent probes glucose uptake cells viability contrast reagents neoplasia cancers diabetes flow cytometry microscopy 213484-93-6 93.043431031821
10010494 2-PCPA (hydrochloride) - ≥98% 2008-05-09 0.466140489344 2-pcpa-hydrochloride trans-2-Phenylcyclopropylamine; Tranylcypromine 2 PCPA 2PCPA LSD1 histones chromatin nucleosomes post-translational modifications posttranslational methylation demethylation inhibitors inhibits inhibition MAO A B I MAOA MAOB MAOI MAO-A MAO-B MAO-I depression anxiety parkinsons disease epigenetics monoamine oxidases lysine-specific demethylase 0.466140489344
10009651 2-thio-Acetyl MAGE 112014-15-0 ≥97% 2007-02-22 8.737748618784 2-thio-acetyl-mage KIAA1363 cancers colorimetric substrates activity inhibition inhibits inhibitory enzymatic activity 8.737748618784
10004185 3,4',5-Trismethoxybenzophenone Exclusive 94709-12-3 >95% ✓ 2004-07-21 28.448931860036 3-4-5-trismethoxybenzophenone antimitotics antimitosis resveratrol analogs phenolic antioxidants antiproliferative antiproliferatory inhibits inhibition inhibitors cell growth 28.448931860036
10727 3,5-dimethyl PIT-1 701947-53-7 ≥98% 2011-05-25 12.344984039287 3-5-dimethyl-pit-1 PIP3 PtdIns-(3,4,5)-P3 PH domain cancers inhibitors Akts PDK1 PTENs proteins binding inhibits inhibited inhibition DM-PIT-1 12.344984039287
10397 3-amino Benzamide 3544-24-9 ≥98% 2011-10-07 2.107037223058 3-amino-benzamide 3-(Aminocarbonyl) Aniline; 3-Carboxamidoaniline poly(ADP-ribose) polymerases PARPs DNA repairs DNA strands breaks apoptosis inflammation atherosclerosis neruogenesis cancers angiogenesis signaling cellular responses inhibits inhibitor inhibition telomere shortening shortens stimulates mediated mediates PARP-mediated 2.107037223058
13574 3-bromo-5-phenyl Salicylic Acid Exclusive 4906-68-7 ≥95% ✓ 2010-08-10 16.991309392265 3-bromo-5-phenyl-salicylic-acid NSC 109116 Aldo-keto reductases AKR, oxidoreductases hydroxysteroid dehydrogenases HSDs 20α-HSD progesterones cancers steroids brain functions AKR1C1 AKR1C2 AKR1C3 AKR1C4 endothelial cells 16.991309392265
13828 3-Deazaneplanocin A 102052-95-9 ≥98% 2011-02-18 231.492454617205 3-deazaneplanocin-a DZNep; NSC 617989 EZH2 KMT6 methyltransferases histones cancer epigenetics panobinostat 3deazaneplanocin 3-cyclopentene-1,2-diol deriv Adenosine Adenocard 231.492454617205
13265 4-hydroxy Nonenal Alkyne Exclusive 1011268-23-7 ≥98% ✓ 2010-06-16 136.023106200123 4-hydroxy-nonenal-alkyne Click Tag™ 4-HNE alkyne lipids peroxidation inflammation neurodegeneration atherosclerosis diabetes cancers click chemistry Click Tag™ 4-HNEs alkynes IT 136.023106200123
10495 4-iodo-SAHA 1219807-87-0 ≥98% 2011-01-10 21.372640883977 4-iodo-saha anti-cancers HDACs inhibitors anti-proliferation 4-Hydroxy-5-iodo-3-nitrophenyl)acetyl 4-Hydroxy-3-iodo-5-nitrophenyl)acetyl 5-Iodo-4-hydroxy-3-nitrophenacetyl 5 Iodo 4 hydroxy 3 nitrophenacetyl Nitrohydroxyiodophenylacetate Hydroxyiodonitrophenylacetate Hapten NIP Acetyl Acetyl Hapten NIP NIP Acetyl Hapten NIP-Hapten NIP Hapten 21.372640883977
10185 4-oxo-2-Nonenal Exclusive 103560-62-9 >98% ✓ 2004-01-21 61.709502762431 4-oxo-2-nonenal 4-ONE ROS Alkenals aldehydes free radicals peroxidation lipid autoxidation reactive oxygen species 61.709502762431
10004174 4-oxo 2-Nonenal-d3 Exclusive - ≥99% deuterated forms (d1-d3) ✓ 2004-03-10 32.266666666666 4-oxo-2-nonenal-d3 4-ONE-d3 ROS Alkenals aldehydes free radicals peroxidation lipid autoxidation reactive oxygen species 4-OH-2-nonenal-d3 4-hydroxy2nonenald3 internal standards mass spectrometry GC/MS LC/MS gc-ms ic-ms deuterium deuterateds 32.266666666666
10011049 4-phenyl-5-methyl-1,2,3-Thiadiazole 64273-28-5 ≥98% 2009-03-14 0.337016574585 4-phenyl-5-methyl-1-2-3-thiadiazole NSC 358739 cytochrome P450 CYP450 CYP2B4 CYP2E1 CYP1A2 inhibitors inhibits inhibition thiadiazoles fungicide herbicide plant growth regulator 0.337016574585
11164 5-Azacytidine New 320-67-2 ≥95% 2012-02-16 7.670126563710 5-azacytidine Antibiotic U 18496; Mylosar; NSC 102816; U 18496; NSC 103-627; 5-AzaC; Ladakamycin; WR 183027 52934-49-3 292869-98-8 ledakamycin azacitidine 5-azacitidine 5 azacitidine 5 azacytidine 5-AZCR 5-AZC 5-AC methyltransferases histones cancers epigenetics cytidine inhibitors DNA RNA inhibits inhibition diseases cells 7.670126563710
13379 5-bromo-3-phenyl Salicylic Acid 99514-99-5 ≥95% 2010-08-10 17.205121546960 5-bromo-3-phenyl-salicylic-acid Aldo-keto reductases AKR oxidoreductases hydroxysteroid dehydrogenases HSD 20α-HSD progesterone cancers steroids brain functions AKR1C1 AKR1C2 AKR1C3 AKR1C4 endothelial cells 17.205121546960
11635 5-Fluorocytosine New 2022-85-7 ≥95% 2012-04-16 56.784530386740 5-fluorocytosine Ancobon; Ro 2-9915; 5-FC; Ancotil; NSC 103805 flucytosin fluocytosine fluorocytosine alcobon ancotyl prodrugs 5-fluorouracil cytotoxic inhibitors inhibits inhibition Candida species Cryptococcus neoformans viral infection cancers cytosine deaminase 5 fluorocytosine fluorine drugs DNA proteins sybthesis cells CT26 Tu-2449 tumors flucytosine 56.784530386740
10009315 6-Aminonicotinamide 329-89-5 ≥98% 2008-11-21 1.353038674033 6-aminonicotinamide 6-AN; NSC 21206; SR 4388 inhibitors inhibits inhibition 6-phosphoguconate dehydrogenase cancers ATPs oxidative injury neurodegeneration cardiovascular 1.353038674033
10009856 7-AAD Cell Viability Assay Kit - 2008-10-29 22.474749868935 7-aad-cell-viability-assay-kit 7-Amino Actinomycin D Cell Viability Kit kits 7AAD measurement cells fixation blocking cytoxicity effects environmental toxins drug fluorescence fluorescent cell-based assays cell based assay cba 22.474749868935
600120 7-AAD/CFSE Cell-Mediated Cytotoxicity Assay Kit - 2009-08-05 63.098314917127 7-aad-cfse-cell-mediated-cytotoxicity-assay-kit 7-Amino Actinomycin D/5-(6)-Carboxyfluorescein Diacetate Succinimidyl Ester 7-amino actinomycin D/5-(6)-carboxyfluorescein diacetates succinimidyls esters assays kits measuring measurement kits 5-(6) 5,6 5-6 7AAD cells cytoxicity cell-based cba cytolysis target effector T lymphocytes NK natural killer autoimmune systems pathological cancers multiple sclerosis granule exocytosis pathways Fas diseases graft host 51chromium 51Cr green fluorescent fluorescence probes red propidium iodide dead effector carboxyfluorescein succinimidyl esters dyes damaged DNA deoxyribonucleic acids quantify quantification single staining 63.098314917127
589320 8-hydroxy-2-deoxy Guanosine EIA Kit - 2008-05-21 664.292999210734 8-hydroxy-2-deoxy-guanosine-eia-kit 8-OH-dG ELISA Kit; DNA Damage EIA Kit solid plates oxidative injury stress aging cancers diabetes hypertension hydroxyl radicals peroxynitrite plasmas cells lysates tissues urine creatinine LC-MS liquid DNA damage kits EIAs chormatography mass spectrometry kits enzyme immunoassays elisas 8-OH-2-d 8OH2d 8 oxo deoxyguanine deoxyguanosine hydroxy ohdg 2 EIA/ELISA assays 8-ohdg 8ohdg 664.292999210734
89300 8-hydroxy Guanosine - ≥98% 10.225303867403 8-hydroxy-guanosine oxidative injury RNA stress damage 7,8-dihydro-8-oxo-guanosine markers inhibitors growth 3868-31-3 10.225303867403
13653 ABT-869 796967-16-3 ≥98% 2010-12-09 38.810202578269 abt-869 Linifanib inhibitors RTK tyrosine kinases VEGF PDGF cancers KDR Flt1 Flt3 Flt4 CSF-1R KIT acute myeloid leukemia antiproliferative anti-proliferative ABT 869 ABT869 Indazoles 38.810202578269
10008051 Acid Phosphatase Assay Kit - 2006-09-20 6.430386740332 acid-phosphatase-assay-kit aps hydrolase eznymes prostate pap tartrate resistant assays 6.430386740332
10006908 Adipogenesis Assay Kit - 2006-08-18 97.724003444898 adipogenesis-assay-kit obese obesity cells cycle differentiation inhibits inhibitors inhibition adipocytes cancers origin 3T3-L1 model drug screening adipokines endocrinology cell-based assays cell based assay cba 97.724003444898
10009381 Adipolysis Assay Kit - 2007-07-30 52.117738993721 adipolysis-assay-kit obese obesity cells cycle differentiation inhibits inhibitors inhibition adipocytes cancers origin 3T3-L1 model drug screening adipokines lipolysis 3T3L1 kits assays FFA adipocytes endocrinology cell-based assay cell based assay cba 52.117738993721
11293 Aflatoxin B1 New 1162-65-8 ≥98% 2012-01-30 36.248495222804 aflatoxin-b1 HSDB 3453; NSC 529592; AFB1 11003-08-0 13214-11-4 27261-02-5 toxicology pathogens mycotoxins Aspergillus cancers HCC hepatocellular carcinomas p53 DNA adduct mold carcinogenic metabolism liver epoxide tumoors suppression genes food contaminant contamination D03.438.150.119.075 D03.830.219.119.07 NSC-529592 HSDB-3453 36.248495222804
11294 Aflatoxin B2 New 7220-81-7 ≥98% 2012-01-30 36.009178983488 aflatoxin-b2 Dihydroaflatoxin B1 dihydroaflatoxine B1 toxicology pathogens mycotoxins Aspergillus cancers HCC hepatocellular carcinoma p53 DNA adduct molds carcinogenic carcinogens liver epoxide tumors genes food contamination contaminants pathogens 36.009178983488
11570 AG-014699 New 459868-92-9 ≥98% 2012-03-15 21.205033763044 ag-014699 PF-01367338; Rucaparib phosphate AG-014447 AG 014447 AG-014699 AG-14699 014699 14699 PF 01367338 Poly(ADP-ribose) polymerases PARPs DNA DAN repair deoxyribonucleic acids damages lethal cells mutations BRCA1 BRCA2 therapeutics cancers cell-permeable inhibits inhibitors inhibition PARP-1 chemotherapy activity homologous recombination pathways tumors growths mice mouse epigenetics epigenetically silenced UACC3199 xenograft efficacy temozolomide medulloblastomas 21.205033763044
10010129 AG-041R Exclusive 199800-49-2 ≥98% ✓ 2008-12-16 58.820828729281 ag-041r CCKs gastrin receptors antagonist cancers proliferations apoptosis NS-398 NS398 NS 398 58.820828729281
10010592 AG-1296 146535-11-7 >98% 2008-05-09 7.666917127072 ag-1296 Tyrphostin AG-1296 tyrphostins AG1296 PDGFR PTK SCF inhibitors inhibits inhibition receptors kinases proteins platelet-derived platelet derived growth factors in vitro cancer glioma athrosclerosis restenosis AG1296 AG 1296 7.666917127072
10010244 AG-1478 153436-53-4 ≥98% 2008-04-22 10.902276243094 ag-1478 NSC 693255; Tyrphostin AG-1478 NSC 693255 EGFR PTK inhibitors inhibits inhibition kinases receptors cancers antitumor leioyoma myometrium 175178-82-2 AG1478 AG 1478 t4182 10010244-t4182 10.902276243094
10010248 AG-17 10537-47-0 ≥98% 2007-09-18 1.714819379516 ag-17 NSC 242557; Tyrphostin 9; Malonoben; Tyrphostin AG-17; SF 6847; GCP 5126; RG-50872 proteins tyrosine kinases PTK inhibitors inhibits antiproliferative epidermal growth factor EGF receptors proliferations carcinomas AG17 AG 17 SF6847 SF-6847 GCP-5126 GCP5126 1.714819379516
10010300 AG-18 118409-57-7 >98% 2007-12-20 1.702732681683 ag-18 RG-50810; TX 825; Tyrphostin AG-18; Tyrphostin 23; RG-50858 proteins tyrosines kinases PTKs inhibitors inhibition inhibits antiproliferative epidermal growth factors EGF receptors proliferations carcinoma cancers epidermoid cell lines A431 AG18 AG 18 A23 A-23 A23 RG50810 RG 50810 RG50858 RG 50858 TX-825 TX825 1.702732681683
10010315 AG-183 122520-90-5 ≥98% 2007-09-07 1.496800184161 ag-183 Tyrphostin 51 proteins tyrosine kinases PTKs inhibitors inhibition inhibits inhibition antiproliferative epidermal growth factors EGFs receptors proliferation carcinomas cancers epidermoid AG183 AG 183 1.496800184161
10010314 AG-213 122520-86-9 ≥97% 2008-02-05 2.466539427423 ag-213 Tyrphostin AG-213; Tyrphostin 47 protein tyrosine kinases PTKs inhibitors inhibits inhibition antiproliferative epidermal growth factors EGFs receptors proliferation carcinomas A431 epidermal AG213 Ag 213 118409-60-2 2.466539427423
10010568 AG-370 134036-53-6 >95% (cis/trans mixture) 2009-01-09 1.229594843462 ag-370 NSC 651712 PTK inhibitor tyrphostin tyrosine PDGF receptor kinase EGF receptor antiproliferative 1.229594843462
10010311 AG-490 133550-30-8 ≥98% 2007-12-01 7.543591160220 ag-490 PTK tyrosine kinase inhibitors inhibition inhibits antiproliferatives tyrphostins leukemia Jak-2 Jak2 AG490 7.543591160220
10010242 AG-494 133550-35-3 ≥98% 2008-02-08 1.671809392265 ag-494 protein tyrosine kinases PTKs inhibitors inhibits inhibition antiproliferative RG-13022 epidermal growth factors EGFs receptrors cancers proliferation 1.671809392265
10010312 AG-82 118409-58-8 ≥95% 2008-03-14 4.373550644567 ag-82 Tyrphostin AG-82; NSC 676484; RG-50875; Tyrphostin 25 proteins tyrosines kinases PTKs inhibitors inhibits inhibition antiproliferative epidermal growth factors EGFs receptors proliferation carcinomas blockers A431 AG82 AG 82 RG-50875 RG50875 A25 A-25 4.373550644567
10010243 AG-825 149092-50-2 ≥98% 2008-01-24 2.012059984214 ag-825 Tyrphostin AG-825 Her-2 Her-2/neu erbB tyrosine kinases EGF EGFR cancers anti-cancer prostate breast signal transduction inhibitors inhibition inhibits AG825 AG 825 2.012059984214
10793 AG-879 148741-30-4 ≥95% 2011-05-06 2.752812154696 ag-879 Tyrphostin AG-879 PTKs inhibitors tyrphostins tyrosine kinases antiproliferative NGF TrkA ErbB2 FLK-1 AG879 AG 879 inhibited inhibition 2.752812154696
10010313 AG-99 122520-85-8 ≥98% 2007-12-19 1.334737569060 ag-99 Tyrphostin 46 protein tyrosine kinase PTKs inhibitor inhibits inhibition antiproliferatives epidermal growth factors EGFs receptors proliferation carcinoma cancers blochers EGF-dependent A431 cell lines AG99 AG 99 1.334737569060
13145 AGK2 304896-28-4 ≥98% 2009-10-22 11.670718232044 agk2 sirtuins SIRT2 histones deacetylase HDAC cells cycle progression tumorigenesis cancers SIRT1 SIRT3 dopamine neurons α-synuclein Parkinson's diseases neurodegeneration 11.670718232044
19023 AH 23848 (calcium salt, hydrate) - ≥90% 2009-02-26 76.191248618784 ah-23848-calcium-salt-hydrate AH23848B AH 23848 TXBs thromboxane PGEs PGE2 receptors prostanoids TPs EP4 antagonist blockers inhibitors inhibits inhibition TXA2 platelets smooth muscle bronchial U-46619 U46619 fibroblasts cancers metastasis 81739-45-9 AH-23848 76.191248618784
10010241 AICAR 2627-69-2 ≥98% 2008-02-25 204.096817679557 aicar NSC 105823; Acadesine; AICA Riboside AMPK lipids metabolism glucose fatty acids sterol HMG-CoA reductases inflammation cytokine iNOS COX-2 MnSOD glia macrophages TNF-.alpha. IL-1.beta. IL-6 aminoimidazole carboxamide ribonucleotide 204.096817679557
160773 AIF Polyclonal Antibody - 0E-12 aif-polyclonal-antibody Programmed Cell Death Protein 8; Apoptosis-Inducing Factor Polyclonal Antibody apoptosis antibodies western blots blotting WB antisera antiserum factors cancers immunoblotting 0E-12
13733 Akt1 (Phospho-Ser473) Monoclonal Antibody (Clone 104A282) - 2010-01-11 1.083188634569 akt1-phospho-ser473-monoclonal-antibody-clone-104a282 antibodies Akts PKBs peptides Akt-1 Akt 1 protein kinase B serine threonine western blots blotting immunoblotting WB IP Immunoprecipitation IP 1.083188634569
13732 Akt1 Polyclonal Antibody - 2010-01-11 1.083188634569 akt1-polyclonal-antibody antibodies Akts PKBs peptides Akt-1 Akt 1 protein kinase B serine threonine western blots blotting immunoblotting WB 1.083188634569
13735 Akt2/3 Polyclonal Antibody - 2010-01-12 1.083188634569 akt2-3-polyclonal-antibody Akt-2 Akt 2 PKB proteins kinase B serine threonine signaling PI3-kinase cancers Western blots blotting immunoblotting WB Akt-3 Akt 3 2-3 1.083188634569
13734 Akt2 Monoclonal Antibody (Clone 95C567.1.2) - 2010-01-12 1.083188634569 akt2-monoclonal-antibody-clone-95c567-1-2 Akt-2 Akt 2 PKB proteins kinase B serine threonine signaling PI#-kinase cancers Western blots blotting immunoblotting WB 1.083188634569
13736 Akt3 Monoclonal Antibody (Clone 66C1247.1) - 2010-01-19 1.083188634569 akt3-monoclonal-antibody-clone-66c1247-1 Akt-3 Akt 3 western blot blotting immunoblotting WB Akts protein kinase B PKB serin threonine signaling proteins 1.083188634569
10010079 Akt (human recombinant) Western Ready Control Exclusive - ✓ 2008-08-26 3.961519337016 akt-human-recombinant-western-ready-control Protein Kinase B; PKB; AKT1 western blots proteins antibodies antiserum antisera WB kinases serine threonine hexahistidine his-tag his-tagged N-terminal immunoblotting blotting 3.961519337016
10009350 Aldehyde Reactive Probe (trifluoroacetate salt) 627090-10-2 ≥98% 2008-08-26 9.526629834254 aldehyde-reactive-probe-trifluoroacetate-salt O-(Biotinylcarbazoylmethyl) Hydroxylamine; ARP DNA damages AP sites synthesis mutations ROS biotin oxidative stress detection detecting 139585-03-8 9.526629834254
13144 Anacardic Acid 16611-84-0 ≥98% 2010-02-12 5.862559731964 anacardic-acid 6-pentadecyl Salicylic Acid HAT histones acetylation P300 pCAF transcription NF-κB IκBα p65 6-pentadecyl salicyclic acids NSC 623096 cyclogallipharic 229596 333857 5.862559731964
11308 Anisomycin New 22862-76-6 ≥98% 2012-02-13 29.177773401653 anisomycin NSC 76712; Flagecidin; Wuningmeisu C 2322-08-9 11023-48-6 antibiotics inhibitors proteins DNA stress-activated kinases MAP caspase-8 cancers immunology immunosuppressant pyrrolidines Streptomyces griseolus synthesis signal transduction pathways T cells skin mice anoikis epithelial apoptosis ECM distal tumors prostate metastasis NSC76712 NSC-76712 29.177773401653
600300 Annexin V FITC Assay Kit - 2010-05-11 89.072887682310 annexin-v-fitc-assay-kit assays kits measures measurements apoptosis cells death cycles tissues homeostasis dysregulation neurodegenerative diseases ischemic damages autoimmune disorders cancers drugs discovery signaling pathways membranes phospholipids phosphatidylserines phosphatidylethanolamines leaflets bilayers externalizations residues plasma phospholipids binding proteins fluorochrome-labeled fluorochromes fluorescence microscopy flow cytometry FC plate readers TUNEL TdT-mediated dUTP Nick-End Labeling analysis ISEL in situ end labeling DNA laddering detection fragmentation FITC-conjugated fluoresceins 89.072887682310
160780 Apaf-1 Polyclonal Antibody - 1.795193370165 apaf-1-polyclonal-antibody Apoptosis Protease-Activating Factor 1 apoptosis cell death caspases CED-4 Apaf2 Apaf3 Apaf-2 Apaf-3 Apafs antibodies Apaf1 CED4 western blots blotting WB protease-activating factors proteases antisera antiserum cancers immunoblotting 1.795193370165
10575 Apicidin New 183506-66-3 ≥98% 2012-01-27 21.579683293496 apicidin OSI 2040 funfal toxins malaria HDAC HAT histones deacetylase transcriptions epigenetics anticancer anti-cancer antiproliferation antiparasitic anti-proliferation anti-parasitic apicomplexan parasites HDAC3 HDAC-3 NcoR HDAC3/NcoR class I HDACs p21 WAF1/Cip1 WAF1 Cip1 gelsolin cells cycle morphology inhibits inhibitors inhibitions chromatin cancers deacetylase modification 21.579683293496
10006797 Araguspongin B 123000-02-2 >90% 2005-09-09 45.826433394721 araguspongin-b membrane-permeable antagonists inositols inositol-1,4,5-triphosphates receptors marine products Pacific basin sponges vasodilatory properties signal transductions messengers IP3 promotes mobilization calcium Ca2+ intracellular stores antagonizes calcium-releasing actions cerebral microsomes Xestospongin C neuroscience 45.826433394721
160737 ARC Polyclonal Antibody - 9.843397790055 arc-polyclonal-antibody Apoptosis Repressor with CARD apoptosis cell death domain DD CARD caspase antibodies western blots blotting WB antisera antiserum cancers immunoblotting IP immunoprecipitation 9.843397790055
13321 ARP 100 704888-90-4 ≥98% 2009-10-07 2.175690607734 arp-100 MMP-2 Inhibitor III; CAY10609 matrix metalloproteinases MMP-2 MMP2 MMP 2 ECM cancers cells migration inhibitors gelatinase A MMPs proteases HT1080 tumors invasive 2.175690607734
13250 (−)-AS 115 926657-43-4 ≥98% 2009-05-18 2.622762430939 -as-115 KIAA1363 MAGE monoacylglycerol LPA LPC lysophosphatidylcholine lysophosphatidic acid lipids signaling cancers signalling 2.622762430939
10009650 (+)-AS 115 - ≥98% 2009-05-19 0.874254143646 -as-115 KIAA1363 MAGE monoacylglycerol LPA LPC lysophosphatidylcholine lysophosphatidic acid lipids signaling cancer 0.874254143646
11226 AS-703026 New 1236699-92-5 ≥98% 2012-03-08 27.541067090939 as-703026 MSC1936369B AS 703026 AS703026 1204531-26-9 MEKs MEK1/2 MEK-1/2 MEK1 MEK2 ERKs Ras Raf inhibitors inhibits inhibitions cancers multiple myeloma EGFR signals transductions kinases cells biology 27.541067090939
700420 Ascorbate Assay Kit - 2010-09-01 209.529591160221 ascorbate-assay-kit L-Ascorbic Acid Assay Kit; Vitamin C Assay Kit kits assays measures measurements ascorbates six-carbon 6-carbon six 6 carbons lactones glucose livers mammalian species humans non-human primates guinea pigs gulonolactones oxidases acids 2-keto-1-gulonolactone diets dietary scurvy electrons donors enzymes collagen hydroxylations hydroxyls groups prolines lysines molecules carnitines fatty mitochondrias ATP adenosine triphosphates generations biosynthesis norepinephrines dopamines amides groups peptides hormones tyrosines metabolisms antioxidants chronics diseases cancers cardiovascular cataracts foods industry colors tastes odors plasmas serums urines fruits juices condensations reactions dehydroascorbic DHA o-phenylenediamines OPDA fluorescent fluorescences 4-hydroxy-2,2,6,6-tetramethylpiperidinyloxy TEMPOL condensed DFQ 3-(dihydroxyethyl)-furo[34-b]-quinoxaline-1-one OPD 209.529591160221
10946 Ash2L (human recombinant) - ≥90% 2011-06-29 12.972715102576 ash2l-human-recombinant Set1/Ash2 Histone Methyltransferase Complex Subunit Ash2 Isoform A; Absent, small, or homeotic discs 2-like epigenetics methyltransferases histones H3K4 genes regulations MLL proteins complex human homolog Drosophilia ash2 transcription 12.972715102576
13375 Atrazine 1912-24-9 ≥98% 2010-02-11 0E-12 atrazine herbicides plants cancers reproductive systems reproduction homones endocrines frogs genes expressions humans animals Gesamprim Atrazine 0E-12
600140 Autophagy/Cytotoxicity Dual Staining Kit - 2009-07-14 80.606732438832 autophagy-cytotoxicity-dual-staining-kit assays kits measuring measurement MDC cell-based autophagy cells cytotoxicity staining autofluorescent autofluorescence substances multilamellar body bodies ions trapping mechanisms membranes lipids probes autophagic vacuoles cultured degradation digestion intracellular lysosomes organelles misfolded proteins microorganisms cytoplasms double membranes autophagosomes autolysosomes homeostasis dysregulation cancers infections aging degenerative diseases stress death apoptosis 80.606732438832
10803 Autotaxin (human recombinant) - ≥95% 2011-04-04 14.860662983425 autotaxin-human-recombinant Ectonucleotide Pyrophosphatase/Phosphodiesterase-2; Lysophospholipase D; ENPP-2 lipids hydrolysis lysophophatidyl choline lysophophatidic acids secreated glycosylated active 14.860662983425
700580 Autotaxin Inhibitor Screening Assay Kit - 2011-06-28 16.120036832412 autotaxin-inhibitor-screening-assay-kit ATX Inhibitor Screening Assay Kit kits assays measures measurements Ectonucleotides Pyrophosphatase-2 ENPP-2 Lysopholipases D hydrolysis lysophosphatidylcholines LPC lysophosphatidic acid LPA lipids mediators G protein-coupled receptors GPCRs neurogenesis angiogenesis smooth-muscles contraction platelets aggregations wounds healings ATX-LPA signaling tumors progression inflammation serums proteolytically peptides proteins N-glycosylation Asn53 Asn410 adipocytes cerebrospinal fluid multiple sclerosis livers fibrosis cancers genes chips analysis upregulated metastatic inhibits inhibition human 16.120036832412
11491 AZD 7762 New 860352-01-8 ≥98% 2012-04-11 51.111111111111 azd-7762 1019773-80-8 DNA damage repair checkpoints cells cycles kinases Chk1 Chk2 S phases G2 tumors cancers inhibitors inhibits inhibition AZD-7762 AZD7762 ATP Chk-1 Chk-2 Chk 1 Chk 2 51.111111111111
10009644 BAY-43-9006 284461-73-0 ≥98% 2011-09-13 25.839792817680 bay-43-9006 Sorafenib; Nexovar® inhibitors raf-1 b-raf receptors tyrosine kinases VEGF VEGFR PDGF PDGFR cancers angiogenesis apoptosis tumors cells cellular proliferation Flt-3 c-KIT carcinoma growth factor tosylate 25.839792817680
11571 Bexarotene New 153559-49-0 ≥98% 2012-04-06 47.635666052793 bexarotene LGD 1069; SR 11247; Ro 26-4455; LG 100069; Targretin retinoid X receptors ligands agonist RXR genes expression cancers alzheimers diseases apoptosis angiogenesis metastasis cells proliferations β-amyloid amyloids βamyloid LG 100069 1069 69 LG-100069 LG-1069 LG-69 LGD 1069 LGD-1069 LGD1069 LG100069 LG1069 LG69 RO 26-4455 RO26-4455 RO-26-4455 RO 264455 RO-264455 RO264455 SR 11247 SR-11247 SR11247 targret targretin targretyn targrexin 47.635666052793
11022 BIBF 1120 928326-83-4 ≥95% 2011-11-10 6.088397790055 bibf-1120 Vargatef™ receptors tyrosine kinases inhibitors vascular endothelial growth factor VEGFR platelet-derived growth PDGFR fibroblasts FGFR angiogenesis cancers pulmonary fibrosis diseases 6.088397790055
10011385 Bim/BOD (IN) Polyclonal Antibody - 2008-04-10 3.051395027624 bim-bod-in-polyclonal-antibody apotosis BH3 Bcl-2 Bcl-XL cancer immunoblotting WB IHC antibodies western blotting antiserum blots immunohistochemistry 3.051395027624
10960 Bisdemethoxycurcumin 24939-16-0 ≥98% 2011-08-09 23.565733578882 bisdemethoxycurcumin BDMC curcumin activators macrophages phagocytosis 1α,25-dihydroxyvitamin D, amyloid-β Alzheimer’s diseases cancers transcription genes expression p300 Wnt/β-catenin iNOS inflammation bisdemethoxy curcumin 33171-05-0 23.565733578882
11071 BRD2 bromodomain 1 (human recombinant; GST-tagged) - ≥95% 2011-10-21 21.617085211800 brd2-bromodomain-1-human-recombinant-gst-tagged RNF3; Bromodomain containing 4; RING3 BET proteins BRD2 BRD3 BRD4 I-BET genes expression histones chromatin acetylation IBET BRD BRD-2 BRD-3 BRD-4 bromodomain epigenetics lysine inflammatory inflammation mitosis viral host 21.617085211800
11070 BRD2 bromodomain 2 (human recombinant; GST-tagged) - ≥95% 2011-10-21 19.476201233899 brd2-bromodomain-2-human-recombinant-gst-tagged RING3; RNF3; Bromodomain containing 4 BET proteins BRD2 BRD3 BRD4 I-BET genes expression histones chromatin acetylation IBET BRD BRD-2 BRD-3 BRD-4 bromodomain epigenetics lysine inflammatory inflammation mitosis viral host 19.476201233899
11069 BRD2 bromodomains 1 and 2 (human recombinant) New - ≥90% 2011-12-20 22.742155953254 brd2-bromodomains-1-and-2-human-recombinant Bromodomain containing 2; RNF3; RING3 BET proteins BRD2 BRD3 BRD4 I-BET genes expressions histones chromatin acetylation IBET BRD BRD-2 BRD-3 BRD-4 bromodomains epigenetics lysines regulations trandcription proteins domains nucleosomes BRDT BRD-T cells inflammatory inflammation mitosis viruses viral hosts binding binds molecules inhibitors inhibits inhibition humans diseases 22.742155953254
11068 BRD4 bromodomain 1 (human recombinant; GST-tagged) - ≥60% 2011-10-21 31.131678012537 brd4-bromodomain-1-human-recombinant-gst-tagged MCAP; Bromodomain containing 4; HUNK1 BET proteins BRD2 BRD3 BRD4 I-BET genes expression histones chromatin acetylation IBET BRD BRD-2 BRD-3 BRD-4 bromodomains epigenetics lysine nucleosomes cellular inflammatory mitosis viral hosts 31.131678012537
11066 BRD4 bromodomain 2 (human recombinant; GST-tagged) - ≥95% 2011-10-21 23.292605823785 brd4-bromodomain-2-human-recombinant-gst-tagged MCAP; Bromodomain containing 4; HUNK1 BET proteins BRD2 BRD3 BRD4 I-BET genes expression histones chromatin acetylation IBET BRD BRD-2 BRD-3 BRD-4 bromodomains epigenetics lysine nucleosomes cellular inflammatory mitosis viral hosts 23.292605823785
11052 BRD4 bromodomains 1 and 2 (human recombinant) New - ≥90% 2011-12-20 25.119793084056 brd4-bromodomains-1-and-2-human-recombinant HUNK1; Bromodomain containing 4; MCAP BET proteins BRD2 BRD3 BRD4 I-BET genes expressions histones chromatin acetylation IBET BRD BRD-2 BRD-3 BRD-4 bromodomains epigenetics lysines regulations trandcription proteins domains nucleosomes BRDT BRD-T cells inflammatory inflammation mitosis viruses viral hosts binding binds molecules inhibitors inhibits inhibition humans diseases 25.119793084056
11509 BRD9 bromodomain (human recombinant) New - ≥95% 2012-04-20 65.853947880323 brd9-bromodomain-human-recombinant Bromodomain-containing 9 BRD9 genes expressions histones chromatin acetylation bromodomains epigenetics BET domains transcription Extra Terminal domain BRDs BRDT inflammatory mitosis viral/host interactions Rhabdomyosarcoma antigen MU-RMS-40.8 65.853947880323
11284 BRG1 bromodomain (human recombinant) New - ≥95% 2012-03-05 12.837710969321 brg1-bromodomain-human-recombinant BRG1-associated factor 190A; BAF190A Mitotic growth and transcription activator; ATP-dependent helicase SMARCA4; Protein BRG-1 BRG1 genes expressions histones chromatin acetylation bromodomains epigenetics SWI/SNF SWI SNF cancers tumors suppressors Protein brahma homolog 1 12.837710969321
11289 BRM bromodomain (human recombinant) New - ≥95% 2012-03-01 8.128331573859 brm-bromodomain-human-recombinant SWI/SNF ATPase; SMARCA2A/B BRD1 genes expressions histones chromatin acetylation bromodomains epigenetics SWI/SNF SWI SNF ATP dependent chromatin SWI/SNF-related, matrix associated, actin-dependent regulator of chromatin 8.128331573859
10005270 C75 191282-48-1 ≥98% 2004-09-22 23.309447513812 c75 inhibits inhibitors inhibition fatty acids synthases FAS cerulenin cytotoxicity apoptosis cancers anorexigenic stable weight loss feeding endocrinology 23.309447513812
13285 Cannabidiol dimethyl ether 1242-67-7 ≥98% 2009-05-19 8.183425414364 cannabidiol-dimethyl-ether Cannabidiol-2',6'-dimethyl ether; CBDD 15-lipoxygenases 15-LOs dioxygenase fatty acids inflammation thrombosis cancer LDL oxidation inhibitions inhibition inhibiting cannabinoids cbs synthetic 8.183425414364
10487 Capecitabine 154361-50-9 ≥98% 2010-08-16 14.873848987108 capecitabine Ro 09-1978; Xeloda® Capecitibine Capecytabine Captabin 5-Fluorouracil 5-FU cancers prodrugs thymidine phosphorylase fluoropyrimidine carbamate inhibits inhibition inhibitors thymidylate synthase liver enzymes 158798-73-2 958887-39-3 Deoxyribonucleoside Cytosine Cytosine Deoxyribonucleoside Deoxyriboside Cytosine Cytosine Deoxyriboside Deoxycytidine CDR 14.873848987108
89800 Carnosol 5957-80-2 >96% 138.812083662193 carnosol antioxidants tumors herbs carcinogenesis rosemary Rosmarinus officinalis extracts polyphenolic inhibits inhibitors inhibition 138.812083662193
360745 Caspase-3 (human) Blocking Peptide - 0.613412664683 caspase-3-human-blocking-peptide Yama; ICE3; CPP32; Apopain control peptides blots blotting western cpp-32 ice-3 apoptosis effectors caspases cell death wb antibodies 0.613412664683
160790 Caspase-9 Polyclonal Antibody - 8.802121546961 caspase-9-polyclonal-antibody MCH6 Polyclonal Antibody; ICE-LAP6 Polyclonal Antibody; Apaf-3 Polyclonal Antibody apoptosis cell death Apaf-1 apafs caspase-3 caspases antibodies Apaf1 western blots blotting WB an tisera antiserum cancers immunoblotting 8.802121546961
13704 Cav3.2 Calcium Channel Monoclonal Antibody (Clone S55-10) - 2009-11-12 6.408839779006 cav3-2-calcium-channel-monoclonal-antibody-clone-s55-10 antibodies CACNA1H genes epilepsy up-regulations up regulations upregulations prostate cancers androgen-independent androgen independent western blotting blots WB fusion protein immunohistochemistry IHC immunocytochemistry ICC 6.408839779006
89740 CAY10398 Exclusive - ≥98% ✓ 23.111616832978 cay10398 reversible inhibitors histone deacetylase HD1 inhibits inhibitions CAY-10398 hdacs HDAC-1 HDACs HDAC 1 HDAC1 HDACIS 23.111616832978
70635 CAY10416 443919-96-8 >95% 2007-07-24 31.926498618784 cay10416 COX-2 cyclooxygenases 5-LO lipoxygenases inflammation inhibitors prostates cancers PC3 LNCaP carcinomas apoptosis inhibition inhibits chemotherapy cells lines 31.926498618784
10005019 CAY10433 537034-17-6 >98% 2005-01-05 26.725718232044 cay10433 BML-210; N-phenyl-N'-(2-Aminophenyl)hexamethylenediamide HDAC deacetylases histone inhibits inhibitors inhibition cancer cells differentiation gene expression regulation Trichostatin A nuclear extracts deacetylation transcription factors FOXO3 SIRT1 H2O2 hydrogen peroxides BML210 26.725718232044
10005033 CAY10444 Exclusive 298186-80-8 ≥98% ✓ 2004-10-05 58.748941068140 cay10444 BML-241 receptors antagonists S1P3 EDG3 sphingosines sphingosine-1 sphingosine1 phosphates Hela cells G-proteins CAY-10444 BML241 58.748941068140
10006546 CAY10465 Exclusive 688348-33-6 >98% ✓ 2005-09-09 17.266060564257 cay10465 resveratrol analogs analogues aryl hydrocarbons receptors agonists AhRs ligand-dependents ligands xenobiotics PDM 11 PDM11 PDM-11 estrogen dioxin poisonings stilbene xenobiotics polyaromatics soot coal tar 17.266060564257
10008872 CAY10503 - ≥98% 2007-08-02 80.509723756906 cay10503 apoptosis antiproliferation cancers differentiation HL60 cells cycles proliferative positive markers CD14 CD11b CD11c monocytic granulocytic 80.509723756906
10009078 CAY10505 328960-84-5 ≥98% 2009-11-04 7.700023327194 cay10505 phosphoinositide 3-kinase immunity autoimmune inflammation PI3Kγ PI3Kα PI3Kβ PI3Kδ casein kinases 2 CK2 phosphorylation PKB/Akt macrophages neutrophil recruitment cancer PI3s T2Ds PI3Ks PI3K.gamma. PI3Kg 7.700023327194
10009536 CAY10512 Exclusive 139141-12-1 ≥97% ✓ 2007-07-18 28.156942909760 cay10512 analogs resveratrol nuclear factors NFkB NF-.kappa.B immunity inflammation stress growth apoptosis trans-stilbene activation cancers NF-kB inhibition inhibtors inhibits atherosclerosis 28.156942909760
10010301 CAY10554 267654-00-2 ≥95% 2007-12-01 10.028232044198 cay10554 BML-259 cell cycle cdk5 cdk2 inhibitors inhibits inhibition cancers BML 259 BML259 CDKs neurodegenerative diseases 10.028232044198
10010043 CAY10561 Exclusive 933786-58-4 ≥98% ✓ 2008-03-06 13.732486187846 cay10561 Pyrazolylpyrrole ERK Inhibitor MEK Ras Raf ERK2 proliferation cell cycles cancers apoptosis inhibition inhibit inhibitors 13.732486187846
18218 CAY10572 845714-00-3 ≥98% 2009-03-02 13.921418047882 cay10572 PHA 767491 inhibits inhibition inhibitors cdc7 kinases pyrrolopyridinone DNA synthesis cells death cycles apoptosis p53 cancers cdk9 antitumor agents anti-tumor 13.921418047882
10011247 CAY10574 140651-18-9 >95% 2008-09-04 13.999403314917 cay10574 CDK2 cyclin E CDK9 inhibitors inhibits inhibition anticancer cell cycle CAN508 13.999403314917
10011256 CAY10577 300675-28-9 ≥95% 2008-09-02 0.613259668508 cay10577 inhibitors inhibits inhibition CK2 kinase cell signaling apoptosis cancers 0.613259668508
10011264 CAY10578 19231-60-8 ≥95% 2008-08-26 0.613259668508 cay10578 inhibitors inhibits inhibition kinase cell signaling CK2 apoptosis cancers isoindolineacetic acids 0.613259668508
16835 CAY10580 Exclusive 64054-40-6 ≥96% ✓ 2009-03-16 77.803241252302 cay10580 PGEs PGE2 receptors inhibitors inhibits inhibition antagonist blockers EP4 cAMPs bones fromation resorption cancers atherosclerosis 77.803241252302
16838 CAY10581 Exclusive 1018340-07-2 ≥97% ✓ 2009-05-08 2.261049723757 cay10581 indoleamine 2,3-dioxygenase IDO cancers inhibitors tumors inhibition inhibited naphthoquinones 2.261049723757
10012682 CAY10585 934593-90-5 ≥97% 2008-11-06 48.964775059194 cay10585 Hypoxia Inducible Factor-1α Inhibitor HIF-1α HIF1α hypoxia cancers transcriptions factors VEGFs erythropoietin inhibitors inhibits inhibition 48.964775059194
10009797 CAY10591 Exclusive 839699-72-8 ≥98% ✓ 2008-04-21 39.731274401472 cay10591 Sirtuin 1 Activator 3; SIRT1 Activator 3 p53 HDACs inhibits inhibitors inhibitions SIRTs sirtuins class III TNFalpha TNF.alpha. THP-1 cells anti-obesity anti-diabetic 39.731274401472
13206 CAY10593 Exclusive - ≥95% ✓ 2009-09-03 34.926662983425 cay10593 VU0155069 inhibitors inhibits inhibitions phospholipases D PLD PLD1 PLD2 phosphatidic acids PAs chemotaxis cells migration cancers breast lines tumors trans well assays 1130067-06-9 34.926662983425
13281 CAY10598 Exclusive 346673-06-1 ≥98% ✓ 2010-05-07 55.690121546961 cay10598 Prostaglandins E2 PGE2 receptors EP4 bone formation cancers atherosclerosis agonists EP1 EP2 EP3 DP FP IP TP neuroprotection renal dysfunction inflammation neuro-protection 55.690121546961
10009796 CAY10602 374922-43-7 ≥95% 2009-07-15 19.163443830570 cay10602 SIRT1 Activator 1 SIRTs sirtuins inflammation deacetylase NF-kB NFkB NF-κB NFκB 19.163443830570
13146 CAY10603 1045792-66-2 ≥95% 2009-06-18 41.899042431909 cay10603 HDAC 6 inhibitors inhibits inhibition tubulin microtubule pancreatic cancers SAHA HDAC6 HDAC-6 HDACs HDACIs potent selective cells 41.899042431909
13291 CAY10616 Exclusive 586410-08-4 ≥98% ✓ 2009-12-01 19.682861878453 cay10616 resveratrols apoptosis cancers leukemia HL-60 cells HL60 HL 60 multidrug-resistance multidrug resistance multi-drug multi-drug-resistant daunorubicin etoposides citarabines phenols cytarabines HL60R 19.682861878453
13670 CAY10618 Exclusive 1202580-59-3 ≥95% ✓ 2011-03-18 12.005966850828 cay10618 NMPRTase Inhibitor nicotinamides phosphoribosyltransferases NAMPTs NAD+ cancers inhibitors autophagy inhibited inhibition inhibits 12.005966850828
13371 CAY10621 120005-55-2 ≥98% 2010-02-16 22.424627071823 cay10621 SKI 5C; SPHK 1 Inhibitor 5C sphingosines kinases Sphk sphingosine-1-phosphates S1P SphK1 SphK2 cancers inhibitors inhibits U937 cells proteins kinase C PKC SKI5C SKI-5C 22.424627071823
13836 CAY10625 137346-42-0 ≥95% 2010-06-23 2.702464088397 cay10625 apoptosis Smac Diablo Survivin cancers antagonists INCENP doxorubicin caspase-3 caspase-7 Aurora B kinases Borealin caspases cell-permeable antagonists smac/diable smac-diablo 2.702464088397
13838 CAY10626 Exclusive 1202884-94-3 ≥98% ✓ 2010-08-23 12.047810517699 cay10626 PI3Kα mTOR cancers signal transduction inhibitors inhibits inhibition phosphatidylinositol 3-kinase PtdIns PIs 12.047810517699
10791 CAY10647 Exclusive New - ≥98% ✓ 2012-04-16 57.198422021906 cay10647 cancers inhibitors inhibits inhibition tumors tubulin polymerization cells CAY-10647 CAY 10647 growth 57.198422021906
10743 CAY10650 Exclusive 1233706-88-1 ≥98% ✓ 2011-06-14 12.111933701657 cay10650 cPLA2α cPLA2 inhibitors inflammation anti-inflammatory dermatitis metabolite phospholipase cytosolic prostaglandins PGs leukotrienes synthesis 10662 CAY-10650 CAY10641 CAY-10641 12.111933701657
11140 CAY10657 New 494772-86-0 ≥98% 2012-03-05 15.173864708261 cay10657 NF-κB, transcription factors inflammation arthritis chemotherapy IKK IKK2 inhibitors IKB thiophenecarboximide inhibits inhibitions IKK-2 IKK 2 NFkB NF kB Rel NF-kB/Rel pro-inflammatory genes cytokines chemokines interferons MHC proteins growth factors cells adhesion cancers 15.173864708261
10004985 Caylin-1 - ≥98% 2005-09-09 16.462107340173 caylin-1 caylin1 mdm-2 cancer Nutlin-3 analogs p53 inhibits inhibitors inhibition interaction Mdm2 negative regulators activity chlorine substituents phenyl rings growth HCT-116 cells promotes 16.462107340173
10005002 Caylin-2 - >98% 2004-07-12 11.607382596685 caylin-2 apoptosis cancer p53 inhibits inhibitors induces apoptotic re-activation reactivation antioncogenic tumors xenografts HCT-116 caylin2 11.607382596685
13172 CBHA 174664-65-4 ≥98% 2009-06-24 20.309815262430 cbha Histone Deacetylase Inhibitor II; m-Carboxycinnamic Acid bis-Hydroxamide histones deacetylase HDACs HDAC1 HDAC3 apoptosis cancers neuroblastoma tumors retinoic acids inhibitors inhibits inhibition 20.309815262430
10787 CCG-100602 1207113-88-9 ≥98% 2011-11-22 6.028416206261 ccg-100602 Rho signaling signal transduction cancers inhibitors SRF serum response factors transcription CCG-1423 megakaryoblastic leukemia 1 MKL1 prostate analogs PC-3 CCG100602 CCG 100602 CCG1423 CCG 1423 cells DNA binding RHOA/C-mediated MKL-1 6.028416206261
10010350 CCG-1423 285986-88-1 ≥98% 2007-09-20 10.328705603788 ccg-1423 Rho signaling transduction cancers proliferations anti-proliferation anti-tumor serum response factor GTPase inhibits inhibitors inhibition signalling 10.328705603788
10012591 CCT018159 171009-07-7 ≥98% 2008-12-09 1.092651933701 cct018159 inhibitors inhibits inhibition cancers Hsp90s Hsp72 kinases tumor cells 17-AAG 17AAG CCT 018159 CCT-018159 1.092651933701
10004804 CD150 Monoclonal Antibody (Clone IPO-3) - 2005-03-21 1.228687845303 cd150-monoclonal-antibody-clone-ipo-3 SLAM; IPO-3; CDw150 type transmembrane glycoproteins signals signalling transduction neoplastic cells antibodies antisera antiserum antioncogenic immunohistochemistry IHC flow cytometry immunoprecipitation IP immunocytochemistry ICC receptors ligation Hodgkins lymphoma leukemia tumors cancer ipo3 cd-150 b-cells t-cells tonsils cancers FC 1.228687845303
10004837 CD27 Monoclonal Antibody (Clone 203.6) - 2005-09-16 7.595037669512 cd27-monoclonal-antibody-clone-203-6 antibodies antisera antiserum IHC immunohistochemistry ICC immunocytochemistry FACS flow cytometry type II transmembranes glycoproteins leukocytes proteins tetraspanin superfamily antigens alternative splicing isoforms human B cells pro-B plasma T macrophages neutrophils platelets erythrocytes Anti-CD37 immunophenotyping neoplasia hairy chronic lymphocytic non-Hodgkin's lymphoma expression lymphocytes T cells NK activated memory monocytes granulocytes dendritic B anti-CD45 mAB lymphoid malignancies malignant cancer FC 7.595037669512
10004835 CD34 Monoclonal Antibody (Clone ICO-115) - 2005-09-16 4.551806204844 cd34-monoclonal-antibody-clone-ico-115 antibodies antisera antiserum ICC immunocytochemistry FACS flow cytometry type I transmembranes glycoproteins proteins antigens isoforms stem cells embryonic fibroblasts neurons Anti-CD34 differential staining acute leukemias cancers malignant malignancies ICO115 FC 4.551806204844
10208 CD34 Monoclonal FITC Antibody (Clone ICO-115) - 2008-07-23 34.607099447513 cd34-monoclonal-fitc-antibody-clone-ico-115 antibodies antiserum antisera flow cytometry immunofluorescence FC IF transmembranes glycoproteins leukemias stem cell lines 34.607099447513
10004718 CD37 Monoclonal Antibody (Clone IPO-24) - 2005-09-16 5.043556002008 cd37-monoclonal-antibody-clone-ipo-24 antibodies antisera antiserum IHC immunohistochemistry ICC immunocytochemistry FACS flow cytometry type III transmembranes glycoproteins leukocytes proteins tetraspanin superfamily antigens alternative splicing isoforms human B cells pro-B plasma T macrophages neutrophils platelets erythrocytes Anti-CD37 immunophenotyping neoplasia hairy chronic lymphocytic non-Hodgkin's lymphoma expression lymphocytes T cells NK activated memory monocytes granulocytes dendritic B anti-CD45 mAB lymphoid malignancies malignant cancer FC 5.043556002008
10004597 CD45 Monoclonal Antibody (Clone BRA-55) - 2005-08-23 5.043556002008 cd45-monoclonal-antibody-clone-bra-55 antibodies antisera antiserum WB western blots blotting IHC immunohistochemistry ICC immunocytochemistry FACS flow cytometry type transmembranes glycoproteins leukocytes antigens alternative splicing isoforms CD45RA CD45RB CD45RC CD45RO expression lymphocytes cells NK activated memory monocytes granulocytes dendritic anti-CD45 mAB lymphoid malignancies malignant cancer BRA55 immunoblotting FC 5.043556002008
10009852 CD4/CD8 Monoclonal FITC/PE Antibody (Clone RIV7/OKT-8) - 2008-09-03 0.417248618784 cd4-cd8-monoclonal-fitc-pe-antibody-clone-riv7-okt-8 antibodies antisera antiserum FC flow cytometry human whole blood cells lysis white CD4-CD8 CD4+CD8 IF immunofluorescence 0.417248618784
10004604 CD95 Monoclonal Antibody (Clone IPO-4) - 2004-06-17 2.077012891344 cd95-monoclonal-antibody-clone-ipo-4 APT; Apoptosis Antigen; TNFRSF6; Tumor Necrosis Factor Receptor Superfamily, Member 6; Fas; APO-1 glycoproteins blots blotting antibodies antisera antiserum DNA binding anti-oncogenic apoptosis cancers p53 re-activator reactivator induces apoptotic re-activation reactivation antioncogenic immunocytochemistry immunohistochemistry IHC icc FC flow cytometry 2.077012891344
10009349 Cell Cycle Phase Determination Kit - 2007-04-20 66.600055248619 cell-cycle-phase-determination-kit assays kits measures measurements microscopy flow cytometry plate readers regulators cells transcription factors DNA proteins division proliferation induction inhibition fixation permeabilization staining sub-G1 G0 G2 S propidium iodide apoptosis cancer cell-based assay cell based assay cba 66.600055248619
11092 Ceranib-2 New - ≥98% 2011-12-19 5.143965738907 ceranib-2 ceramides ceramidase sphingosines sphingosine-1-phosphate S1P cells proliferation cancers paclitaxel tumors inhibitors lipids inhibits inhibition endogenous ovarian SKOV3 growth toxicity fatty acids N-acyl malignant apoptosis S1P non-lipid increases increased 5.143965738907
10005647 Cerulenin 17397-89-6 ≥98% 2004-09-01 30.217458563535 cerulenin tumor cells fatty acid synthases FAS inhibits inhibitors inhibition cytotoxicity apoptosis cancer diet obesity D02.065.327 30.217458563535
10009853 CFSE Cell Division Assay Kit - 2010-01-15 63.844708882277 cfse-cell-division-assay-kit derivative carboxyfluorescein diacetate, succinimidyl ester CFDA-SE cells proliferation growth factors receptors surfaces signaling molecules transcription factors DNA deoxyribonucleases proteins divisions cascades human pathological diseases cancers cell-tracing fluorescent fluorescence dyes proliferative activity parent generations daughter acetate groups molecules cleaved background unstained staining CFSE-labeled radioactivity radioactive labeling divisions inductions inhibitors inhibits inhibitions in vitro models flow cytometry fluorochromes fluorescein 63.844708882277
13156 Chaetocin 28097-03-2 ≥95% 2010-10-18 18.632886024146 chaetocin histones methyltransferases HMTs genes expressions epigenetics inhibitors oxidative stress cancers theoredoxin reductase-1 TrxR1 inhibits inhibition chetocin chaetocin A (+)-chaetocin piperazines 18.632886024146
10011286 Chenodeoxycholic Acid 474-25-9 ≥95% 2009-02-25 30.085602209944 chenodeoxycholic-acid Ulmenide; Kebilis; Anthropodeoxycholic Acid; Hekbilin; Fluibil; CDCA FXR biles acids cholesterol oxidative stress glutathione cancers atherosclerosis diabetes hyperlipidemia CDA 30.085602209944
13686 Chidamide 743420-02-2 ≥98% 2010-08-10 39.909907100471 chidamide HDACs histones deacetylase H3 acetylation colons cancers cells inhibitors inhibits inhibiton LoVo HT-29 HT29 HT 29 cycle arrest chidamides oncogenic signalling signaling kinases Benzamides 39.909907100471
70930 Chlorogenic Acid 327-97-9 ≥95% 27.926546961325 chlorogenic-acid NSC 407296; Heriguard; 3-O-Caffeoylquinic acid antioxidants acids plants metabolism polyphenolic 27.926546961325
13501 Chromosome Associated Protein-C Polyclonal Antibody (aa 281-297) - 2009-09-22 0E-12 chromosome-associated-protein-c-polyclonal-antibody-aa-281-297 CAP-C antibodies SMC WB western blots immunoblotting blotting hCAP-C hCAPC hCAP C hSMC1 hCAP-E hCAP E hCAPE hSMC3 chromosomes structured maintenance 0E-12
13503 Chromosome Associated Protein-C Polyclonal Antibody (aa 47-61) - 2009-09-22 0E-12 chromosome-associated-protein-c-polyclonal-antibody-aa-47-61 CAP-C antibodies SMC WB western blots immunoblotting blotting hCAP-C hCAPC hCAP C hSMC1 hCAP-E hCAP E hCAPE hSMC3 structural maintenance chromosomes 0E-12
11021 CHS-828 New 200484-11-3 ≥98% 2012-03-14 21.684931506849 chs-828 GMX 1778 pyridyl cyanoguanidine anti-tumor tumors inhibitors inhibits inhibition NAMPT NF-κB cancers CHS828 CHS 828 humans breasts lungs mice MCF-7 NYH GMX-1778 GMX1778 21.684931506849
10012583 cis-ACCP 777075-44-2 ≥95% 2009-02-10 0.085082872928 cis-accp MMP2 MMPs MMP 2 MMP9 MMP-9 9 tumors cancers extracellular matrix type IV collagen cell migration artritis osteoprosis 0.085082872928
13199 cis-trismethoxy Resveratrol 94608-23-8 ≥98% 2009-03-25 15.301954419889 cis-trismethoxy-resveratrol cis-Trimethoxy Stilbene resveratrol anti-mitotic growth inhibitors colon cancers tubulin polymerization polyamines putrescine spermidine cis-Trimethoxy resveratrol 3,5,4'-trimethoxystilbene 3,5,4'-trimethoxy-cis-stilbene trismethoxy inhibitor inhibition caco-2 caco 2 cells AHR antagonists aryl hydrocarbon receptors 15.301954419889
10599 Cl-Amidine Exclusive 913723-61-2 ≥95% ✓ 2011-08-29 37.217651933702 cl-amidine inhibitors PAD4 PAD-4 cancers epigenetics amidines proteins arginine deiminase 4 arthritis PADs cytotoxic HL-60 HL60 HT-29 mice joints auto antibodies HL 60 MCF7 MCF-7 MCF 7 HT29 citrulline IgG HT 29 cells lines ClA mouse serum autoantibodies auto-antibodies PAD3 PAD-3 3 PAD1 PAD-1 1 37.217651933702
580110 Clusterin (human) EIA Kit - 2011-08-02 2.154696132597 clusterin-human-eia-kit CLI; SGP-2; KUB-1; AAG4; TRPM-2; pADHC-9; Apo-J; Apolipoprotein J apolipoproteins Up-regulated in Azheimer's diseases brains Ku70-binding proteins 1 sulfated glycoproteins 2 aging-associated genes 4 complement lysis inhibitors testosterone-repressed prostate messages secreted disulfide-linked heterodimeric amyloid lipids bacteria leptin immunoglobulins endocytic receptors LDLs low-density lipoprotein-related LPR2 LPR8 8 endocytosis tissues mammals mammalian cells plasma serums semen cultures media medium developmental remodeling apoptotic neurodegeneration injury stress inhibits inhibition apoptosis carcinogenesis genes CLU ELISAs EIAs enzymes immunoassays kits measures measurements human supernatants 2.154696132597
9000760 Colchicine 64-86-8 ≥98% 2011-05-25 19.853603437692 colchicine microtubules polymerization mitosis anti-proliferation anti-inflammatory gout uric acids antiinflammatory antiproliferation 19.853603437692
10007412 Combrestatin A4 117048-59-6 ≥98% 2007-07-26 25.305512584407 combrestatin-a4 Combretastatin A4; CRC 87-09; CA4 inhibitors inhibition inhibits tubulin polymerization tumors CSA4 CSA-4 IMR32 neuroblastomas Hs746T carcinomas CFPAC-1 CFPAC1 MCF-7 MCF7 cancers inhibitory CA4 cells growth pancreatic breast gastric CA-4 combretastin 25.305512584407
360107 COX-2 (human) Blocking Peptide - 36.381104972376 cox-2-human-blocking-peptide Prostaglandin H Synthase 2; Cyclooxygenase 2; PGHS-2 peptides prostaglandins PGHS-2 COX2 PGHS2 western blots blotting synthases controls immunohistochemistry IHC cyclooxygenases WB antibodies 36.381104972376
160112 COX-2 Monoclonal Antibody (Clone CX229) - 101.238957642726 cox-2-monoclonal-antibody-clone-cx229 PGHS-2; Prostaglandin H Synthase 2; Cyclooxygenase 2 prostaglandins inflammation cancers arthritis western blots blotting immunohistochemistry IHC WB immunocytochemistry ICC antibodies cox2 pghs2 pghs-2 synthases cyclooxygenases antisera antiserum cyclooxygenase immunoblotting 101.238957642726
160126 COX-2 (mouse) Polyclonal Antibody - 119.362861878453 cox-2-mouse-polyclonal-antibody PGHS-2; Prostaglandin H Synthase 2; Cyclooxygenase 2 immunohistochemistry IHC Western blotting WB antibodies blots cox2 PGHS2 PGHS-2 synthases prostaglandins mouse cyclooxygenases antisera antiserum cancers immunoblotting 119.362861878453
10010096 COX-2 (mouse) Polyclonal FITC Antibody Exclusive - ✓ 2008-04-23 29.459263351749 cox-2-mouse-polyclonal-fitc-antibody Prostaglandin H Synthase 2; PGHS2; Cyclooxygenase 2 antibodies prostaglandins thromboxanes prostacyclins arachidonic acids FC flow cytometry ICC immmunocytochemistry WB western blots blotting immunoblotting IF immunofluorescence 29.459263351749
700200 COX Fluorescent Activity Assay Kit - 2008-07-24 82.566610334741 cox-fluorescent-activity-assay-kit Cyclooxygenase Fluorescent Activity Assay Kit cyclooxygenases synthases enzymes cox-1 cox1 cox-2 cox2 prostaglandins PGs synthase-1 synthase-2 pghs-1 pghs1 pghs-2 pghs2 assays kits peroxidase activity cellular homeostasis antiinflammatory NSAIDs nonsteroidal anti-inflammatory drugs fluorescence human recombinant ovine isozyme-specific inhibits inhibitors inhibition ADHP 10-acetyl-3,7-dihydroxyphenoxazine resorufin 82.566610334741
11288 CREB-binding protein bromodomain (human recombinant) Exclusive New - ≥95% ✓ 2012-04-24 70.298392324768 creb-binding-protein-bromodomain-human-recombinant CREBBP; CBP; cAMP-response-element-binding protein binding protein CREBBP genes expressions histones chromatin acetylation bromodomains epigenetics CREB p53 cAMP response element-binding protein 70.298392324768
81025 Curcumin 458-37-7 ≥90% 19.390983425413 curcumin Turmeric Yellow; Indian Saffron anti-oxidant anti-imflammatory NOS nitric oxide synthase 19.390983425413
81025.1 Curcumin (technical grade) 458-37-7 ≥65% 11.220607734806 curcumin-technical-grade Turmeric Yellow; Indian Saffron anti-oxidant anti-imflammatory NOS nitric oxide synthase 11.220607734806
10011388 Cu/Zn SOD (human) Polyclonal Antibody - 23 kDa 2008-04-03 152.239337016574 cu-zn-sod-human-polyclonal-antibody SOD1; Cu/Zn Superoxide Dimutase SOD1 SOD2 SOD3 EC-SOD oxidative stress ROS superoxide antibodies antiserum WB western blots immunoblotting IP EIA IHC immunohistochemistry neurochemistry immunoprecipitation enzyme immunoassays neurochemistry blotting 152.239337016574
11321 Cyclopamine New 4449-51-8 ≥98% 2012-02-20 28.356167127071 cyclopamine Jervine; 11-Deoxojervine 11051-96-0 26108-61-2 veratraman 11-deoxyjervine 11 deoxyjervine hedgehogs development teratogen cancers smoothened inhibitors cyclopia genes expressions signal transduction inhibits inhibition signaling steroids alkaloids pathways pax7 28.356167127071
11328 Cytochalasin B New 14930-96-2 ≥98% 2012-02-22 31.016864586462 cytochalasin-b Phomin; NSC 107658 11032-95-4 11042-65-2 16006-03-4 21476-12-0 inhibitors actin proliferation migration phagocytosis glucose exocytosis cells division chemotaxis inhibits inhibition mycotoxins polymerization NSC-107658 NSC107658 31.016864586462
10004600 Cytokeratin Monoclonal Antibody (Clone C-11) - 2008-06-05 21.336950276243 cytokeratin-monoclonal-antibody-clone-c-11 pan-Cytokeratin cytokeratins pan-cytokeratins antibodies antiserum antisera isoforms western blots WB flow cytometry FC immunocytochemistry ICC immunohistochemistry IHC immunoblotting proteins blotting 21.336950276243
10568 Cytokeratin Monoclonal APC Antibody (Clone C-11) - 2011-03-04 12.923093922652 cytokeratin-monoclonal-apc-antibody-clone-c-11 pan-Cytokeratin cytokeratins pan-cytokeratins antibodies antiserum antisera isoforms flow cytometry FC proteins immunofluorescence IF 12.923093922652
10349 Cytokeratin Monoclonal FITC Antibody (Clone C-11) - 2010-04-14 17.487668508287 cytokeratin-monoclonal-fitc-antibody-clone-c-11 pan-Cytokeratin cytokeratins pan-cytokeratins antibodies antiserum antisera isoforms western blots WB flow cytometry FC immunofluorescence IF immunoblotting proteins blotting 17.487668508287
10478 Cytokeratin Monoclonal PE Antibody (Clone C-11) - 2010-10-28 4.048328729282 cytokeratin-monoclonal-pe-antibody-clone-c-11 pan-Cytokeratin cytokeratins pan-cytokeratins antibodies antiserum antisera anti-serum anti serum anti-ser anti sera isoforms flow cytometry FC immunoblotting proteins blotting IF immunofluorescence 4.048328729282
63500 Cytotrienin A 189010-85-3 ≥95% 2009-07-06 22.799469613259 cytotrienin-a anti-tumor anti-cancer apoptosis ROS caspace-3 p36 MBP kinase JNK 22.799469613259
13305 D 4476 301836-43-1 ≥98% 2009-07-29 39.871657458563 d-4476 Casein Kinase I Inhibitor inhibitors inhibits inhibition casein kinases 1 CK1 Ck1δ TGF-β TGFβ type-1 receptors ALK5 PKD1 p38α MAPK kinases phosphorylation FOXO1a RhoB p53 Smad3 D4476 39.871657458563
13202 Daidzin 552-66-9 ≥98% 2011-09-30 5.582375690608 daidzin NPI 031D; Daidzoside isoflavones soy kudzu anti-oxidants cancers oxidants stress atherosclerosis inhibitor inhibits inhibition mitochondrial aldehydes dehydrogenases 2 alcohols plants anticarcinogenic anti-carcinogenic anti carcinogenic antioxidants antidipsotropic dipsotropic anti-dipsotropic anti-atherosclerosis antiatherosclerosis atherosclerosis 1329-08-4 28572-56-7 NPI-031D NPI031D 7-glucoside glucosides 5.582375690608
160755 DcR2 Polyclonal Antibody - 0E-12 dcr2-polyclonal-antibody TRUNDD; TRAIL-R4 apoptosis cell death TNF DR4 DR5 DcR1 TRID TRAIL antibodies western blots blotting WB antisera antiserum immunoblotting 0E-12
10005432 DDA 25152-84-5 ≥98% 2004-07-22 15.831790055248 dda trans-2,4-Decadien-1-al; Decadienealdehyde lipoxygenases diatoms alkyls linoleic acids dihomo-gamma-linolenic dihomo-g-linolenic arachidonic dihomo-.gamma.-linolenic carcinoma Caco2 apoptosis 15.831790055248
11166 Decitabine New 2353-33-5 ≥98% 2012-02-27 9.013102558266 decitabine Dacogen; 5-aza-2’-Deoxycytidine; NSC 127716; DAC β-decitabine 105597-46-4 123795-43-7 5-azadeoxycytidine 5-azadCyd 5-aza-CdR inhibitors inhibition inhibits epigenetics DNA methylation genes expression methyltransferases hypomethylation mutagenic 9.013102558266
10010706 (−)-Deguelin 522-17-8 ≥98% 2008-09-18 42.460497237569 -deguelin (-)-cis-Deguelin rotenoids flavonids cancers antiproliferative chemoprevention parkinsons diseases Akt PKB PI3K COX-2 COX2 apoptosis PI3-K 42.460497237569
11012 Delphinidin chloride Exclusive New 528-53-0 ≥98% ✓ 2012-03-06 51.662269285860 delphinidin-chloride Ephdine diseases cancers cardiovascular tyrosines kinases vasorelaxation smooth muscles chlorides Cl vasorelaxants inhibitors inhibition inhibits EGFRs epidermal epidermis growth factors receptors HATs histones acetyltransferases anthocyanidins plants pigments anthocyanins blue red colors flowers fruits wines nitric oxides NOs vascular endothelium signaling signalling epithelial estrogens ERa ERalpha ER.alpha. ERα apoptosis cells death autophagy phagocytosis delphinidol 13270-61-6 IdB 1056 IdB-1056 51.662269285860
10961 Demethoxycurcumin 22608-11-3 ≥98% 2011-09-23 4.766151012890 demethoxycurcumin DMC curcumin cancers transcription genes expressions p300 Wnt/β-catenin iNOS inflammation proliferation cells p300 coactivator inhibits lipopolysaccharides inhibitor inhibition 4.766151012890
700390 Demethylase (Jumonji-type) Activity Assay Kit - 2010-05-26 28.154262474787 demethylase-jumonji-type-activity-assay-kit kits assays measures measurements histones nucleoproteins chromatins DNA deoxynucleic acids eukaryotic nucleus nucleosomal H3 H4 H2B H2A octamers amino termini acetylation phosphorylation ubiquitination methylation replication repair transcriptional activation repression dysregulation tumors suppressor genes cancers inhibitors enzymes catalyzes epigenetic marks methyls lysines arginines residues demethylases 1 JMJC JHDM1 JHDM2 JHDM3 JARID1 UTX/UTY cupin 2-oxoglutarate 2OG iron Fe(II) oxygenases hydroxylation JMJD2A JMJD2B JMJD2C JMJD2D JMJD2E JMJD2F fluorescence-based fluorescent cells lysates formaldehydes peptides substrates oxidation/decarboxylation acetoacetanilides ammonia H3K9(Me)3 28.154262474787
700400 Demethylase (LSD-type) Activity Assay Kit - 2010-08-05 17.725588003157 demethylase-lsd-type-activity-assay-kit kits assays measures measurements histones proteins nucleoproteins chromatins structures DNA deoxyribonuclease eukaryotics nucleus nucleosomals core particles H3 H4 H2B H2A octamers amino termini post-translationally acetylation phosphorylations ubiquitination methylations replication repair transcriptional activation repression dysregulation tumor suppressor genes cancers enzymes catalyze epigenetic marks therapeutics drugs development lysine-specific demethylases LSD1 KDM1 p110b BHC110 NPAO LSD2 flavin adenines dinucleotides FAD-dependent amines oxidases monoamines MAOs polyamines PAOs demethylates monomethylateds dimethylateds lysines 4 K4 repression deacetylases co-repressor complexes 1/2 CtBP neuronal CoREST p53 LYS370 53BP1 apoptosis C-terminal domains CW-type zinc finger motif zince-binding sites chromatin-remodeling fluorescence-based formaldehyde N-terminal tail acetoacetanilides ammonia 17.725588003157
10165 D-erythro-MAPP 143492-38-0 >98% 2004-02-23 16.364718465800 d-erythro-mapp (1S,2R-D-erythro-2-N-myristoylamino)-1-phenyl-1-propanol ceramides inhibitors sphingolipids HL60 HL-60 cancer cells G0/G1 G0-G1 inhibits ceramidase 16.364718465800
10012577 Diallyl Trisulfide 2050-87-5 ≥98% 2009-04-07 13.105030536273 diallyl-trisulfide DATS; NSC 651936 garlic hydrogen sulfides H2S cancers tumors smooth muscle cholesterol atherosclerosis donors supresses colon synthesis genes expression adenocarcinomas HCT-15 cells PC-3 xenografts 13.105030536273
10009081 Didox Exclusive 69839-83-4 ≥98% ✓ 2007-01-16 18.713646408839 didox antioxidants hydroxamic acids apoptosis cancers cells polyhydroxylated aromatic ocidative injury brains HIV dementia bcl-2 18.713646408839
10006876 Diethylstilbestrol 56-53-1 ≥98% 2005-10-03 5.535723756905 diethylstilbestrol synthetics receptors agonists pregnant pregnancies linked breasts cancers congenital abnormalities abnormality offspring 3H-estradiols binding affinities affinity sexes hormones globulins SHBG estrogens 5.535723756905
10009986 Dimethoxycurcumin 160096-59-3 ≥90% 2007-08-03 13.619049723756 dimethoxycurcumin curcumins cancers ASCJ9 antitumors anti-tumor phytochemicals turmeric inhibits inhibition inhibitory growth expression cells ASC-J9 13.619049723756
62237 Diphenyl-1-pyrenylphosphine 110231-30-6 ≥98% 2006-07-25 83.155549416820 diphenyl-1-pyrenylphosphine DPPP hydroperoxides oxidative stress injury fluorescence fluorescent lipids cholesterols LDL oxidation DPPPO DPPP=O atherosclerosis 83.155549416820
10005276 DL-threo-PDMP (hydrochloride) 80938-69-8 >98% 2004-08-10 0.661160220994 dl-threo-pdmp-hydrochloride analogs analogues inhibits inhibitors inhibition cytotoxicity glucosylceramides synthases chirality stereoisomers sphingosine 0.661160220994
71210 DMOG 89464-63-1 ≥98% 111.481446110672 dmog Dimethyloxallyl Glycine nuclear receptors cancer hypoxia HIF-1alpha Hif1α HIF-1α HIF1α Pro-angiogenic proangiogenic factors HIF-PH HIFPH prolyl hydroxylase inhibits inhibitors inhibition 111.481446110672
10009851 D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) - >98% 2007-06-04 6.835635359115 d-myo-inositol-1-3-4-5-6-pentaphosphate-ammonium-salt 1,3,4,5,6-IP5 (sodium salt); Ins(1,3,4,5,6)P5 inositols phosphate IP5 signal transduction InsP phosphitidylinositol phospholipase C PLC phosphioinositide 3-kinase PI3-K Akt cancer angiogenesis PKB protein kinase B 6.835635359115
660990 DNA Laddering Kit - 1.477348066298 dna-laddering-kit kits assays apoptosis 1.477348066298
589324 DNA Methylation EIA Kit - 2009-04-23 86.454575966850 dna-methylation-eia-kit 5-methyl-2-deoxy Cytidine ELISA Kit solid plates DNA deoxyribonucleic acids CpG islands dinucleotides genes genomes cancers genomic hypomethylation hypermethylation tumors suppressors malignancy carcinogenesis plasma blood urine leukemia tissues differentiation aging methyltransferases DNMTs DNMT1 DNMT3a DNMT3b nucleosides analogs azacitidine decitabine zebularine drugs suppression competitive assays EIAs ELISAs culture supernatants sample matrices 86.454575966850
13479 DNA Methyltransferase 1 Monoclonal Antibody (Clone 60B1220.1) - 2009-06-29 0.179671823204 dna-methyltransferase-1-monoclonal-antibody-clone-60b1220-1 DNMT1 WB Western blots immunoblotting IHC ChIP IP DNMT 1 blotting immunohistochemistry immunoprecipitation 0.179671823204
13481 DNA Methyltransferase 2 Monoclonal Antibody (Clone 102B1259.2) - 2009-07-13 0E-12 dna-methyltransferase-2-monoclonal-antibody-clone-102b1259-2 DNMT2 WB Western blots immunoblotting DNMT-2 monoclonals blotting DNMT 2 blotting 0E-12
13480 DNA Methyltransferase 2 Polyclonal Antibody - 2009-07-13 0.199635359116 dna-methyltransferase-2-polyclonal-antibody DNMT2 WB Western blots immunoblotting DNMT 2 blotting DNMT-2 0.199635359116
13483 DNA Methyltransferase 3a Monoclonal Antibody - Biotinylated (Clone 64B814.1) - 2009-07-15 0E-12 dna-methyltransferase-3a-monoclonal-antibody-biotinylated-clone-64b814-1 DNMT3a ELISA DNMT3a Enzyme-linked immunosorbent assays 0E-12
13484 DNA Methyltransferase 3a Monoclonal Antibody (Clone 64B1446) - 2009-07-15 0E-12 dna-methyltransferase-3a-monoclonal-antibody-clone-64b1446 DNMT3a WB Western blots immunoblotting DNMT3a blotting ICC immunocytochemistry IHC immunohistochemistry 0E-12
13482 DNA Methyltransferase 3a Monoclonal Antibody (Clone 64B814.1) - 2009-07-01 0.199635359116 dna-methyltransferase-3a-monoclonal-antibody-clone-64b814-1 DNMT3a WB Western blots immunoblotting DNMT3a blotting ICC immunocytochemistry 0.199635359116
13485 DNA Methyltransferase 3b Monoclonal Antibody (Clone 52A1018) - 2009-07-01 0.199635359116 dna-methyltransferase-3b-monoclonal-antibody-clone-52a1018 DNMT3b WB Western blots immunoblotting DNMT3b immunoprecipitation immunofluorescence immunocytochemistry ChIP immunohistochemistry IHC IP ICC IF blotting 0.199635359116
10770 DNA Methyltransferase 3L (human recombinant) - ≥95% 2011-06-08 2.540563835710 dna-methyltransferase-3l-human-recombinant DNMT3L; DNMT3-Like Protein DNA methyltransferases s-adenosylmethionine CpG methylation lysines proteins DNMT3a DNMT3b histones cysteine ADD PWWP mTase 2.540563835710
10006305 D-NMAPPD Exclusive 35922-06-6 ≥98% ✓ 2005-02-23 16.744126481115 d-nmappd CAY10466; (1R,2R)-B13 ceramides inhibitors cancers cells inhibits inhibition ceramidase apoptosis colorectal keratinocytes melanoma lines viability inducers induces 16.744126481115
11637 Docetaxel New 114977-28-5 ≥98% 2012-05-17 100.226746470227 docetaxel NSC 628503; RP 56976; Taxotel; Docetere; Taxotere 129522-72-1 216252-50-5 docetaxol taxol cancers breasts prostate cells proliferation microtubules replication hormones hormone-refactory refractory NSC628503 NSC-628503 RP56976 RP-56976 100.226746470227
700210 DPP (IV) Inhibitor Screening Assay Kit - 2009-05-27 105.254259921503 dpp-iv-inhibitor-screening-assay-kit Dipeptidyl exopeptidases IV DPPIV DPP4 enzymes CD26 cluster of differentiation T-cells activation antigens adenosine deaminase complexing 2 membrane-bound glycoproteins immune regulation signal transduction apoptosis kidneys small intestines placentas humans serums seminal fluids proteolytic derivatives serines X-prolines X-alanines dipeptides N-terminus N-terminal polypeptides growth factors chemokines neuropeptides vasoactive inhibitors inhibits inhibition oral antidiabetic agents glucose homeostasis glucoregulatory hormones glucose-dependent insulinotropics GIP glucagon-like peptide-1 GLP-1 gastric therapeutics Type 2 tumors cancers markers neoplasms assays kits measures measurements fluorescences fluorescent fluorogenics substrates Gly-Pro-Aminomethylcoumarin AMC 105.254259921503
11178 DPY-30 (human recombinant) New - ≥95% 2012-01-05 14.152052839174 dpy-30-human-recombinant DPY-30-like protein; hDPY-30; SAF19 epigenetics methyltransferase histones H3K4 genes regulations MLL proteins subunits Ash2L MLL sore complex DPY30 methylation C. elegans XX mutations XO growth development homodimer monomers WDR5 WDR-5 WDR 5 RbBP5 basal rates DPY-30L DPY30L hDPY30 SAF-19 14.152052839174
10010302 DRB 53-85-0 ≥98% 2008-01-21 4.993093922652 drb Benzimidazole; NSC 401575 cancers HIV P53 apoptosis CDK7 CDK9 CTD CKI CKII adenosine inhibitors inhibits inhibition transcription RNA polymerase cell cycles adenocarcinoma transactivator tat 4.993093922652
10007963 E-64 66701-25-5 ≥98% 2009-11-12 28.585893186004 e-64 inhibitors cysteine proteases cathepsins papain calpain irreversible inhibition inhibited E64 E 64 28.585893186004
10007964 E-64c 76684-89-4 ≥98% 2006-08-02 27.459705340700 e-64c EP 475; Loxistatin Acid; NSC 694279 E-64 cysteine protease cell cycle inhibitor E-64d 27.459705340700
13533 E-64d 88321-09-9 ≥98% 2010-08-16 17.218066298343 e-64d EP 453; EST; NSC 694281; Loxistatin; E-64c ethyl ester; Aloxistatin cysteine protease proteins degradation lysosome inhibitors inhibits inhibition calpain cathepsin E64d E 64d 64 207396-71-2 cells cancers carcinomas A431 E-64d Morphinans 17.218066298343
10005732 EAF2 Blocking Peptide - >75% 2004-09-01 2.024309392265 eaf2-blocking-peptide ELL-Associated Factor 2; U19 WB western blots blotting IHC immunohistochemistry immunoblot formalin-fixed paraffin-embedded sections apoptosis inhibits ihibitors inhibition prostate tumors testosterone antibodies paraffins signaling signalling controls peptides 2.024309392265
10005190 EAF2 Polyclonal Antibody - 2004-08-12 4.412906077347 eaf2-polyclonal-antibody ELL-Associated Factor 2; U19 WB western blots blotting IHC immunohistochemistry immunoblots formalin-fixed paraffin-embedded sections apoptosis inhibits inhibitors inhibition prostate tumors testosterone suppressive supression leukemogenesis cancers endocrinology immunoblotting 4.412906077347
11049 Echinomycin New 512-64-1 ≥98% 2012-03-21 41.796717171717 echinomycin NSC 13502; SK 302B; NSC 526417; Antibiotic A 654I; Quinomycin A 11016-61-8 NSC13502 NSC526417 NSC-13502 NSC-526417 SK302B SK-302B hypoxia HIF-1 cancers neuroscience VEGF inhibitors inhibits inhibition genes expression glycolysis angiogenesis migration invasion cells DNA HIF-1α HIF-1β U215 hippocampal neurons myeloma melphalan 41.796717171717
10628 EED (human recombinant) - 95 2010-12-03 0E-12 eed-human-recombinant Embryonic Ectoderm Development 0E-12
10569 Ellagic Acid 476-66-4 ≥95% 2010-10-13 8.133806015960 ellagic-acid Lagistase; TBBD; Gallogen polyphenols, antioxidants, cancers inflammation cytochrome P450s CYP450 epigenetics genes expression histones modifications alizarin yellow G 91006 elagostasine 77415-21-5 124590-32-5 PRMTs inflammatory anti-carcinogenic anti-mutagenic organ-preserving antimutagenic antiinflammatory Acid Benzoaric Benzoaric Acid Acid Ellagic Ellagic Acid 8.133806015960
10112 (±)-Enterolactone 78473-71-9 ≥95% 9.788729281768 -enterolactone HPMF lignans plants antioxidants cancer oxidative injury stress enterobacterial 9.788729281768
500520 Enterolactone EIA Kit - 2005-03-15 124.724720687537 enterolactone-eia-kit solid plates steroids measures kits eias enzyme immunoassays ELISAs endocrinology assays enterolactones mammalian lignans phytoestrogens estrogen-like diphenols diphenolics intestinal intestines bacterias plant matairesinol secoisolariciresinol diets dietary acute coronary hormone-dependent cancers osteoporosis serums plasmas fiber 124.724720687537
10477 EP2 Receptor Polyclonal PE Antibody - 2010-07-07 30.416372007366 ep2-receptor-polyclonal-pe-antibody Prostaglandin E2 Receptor 2; PGE2 Receptor 2 R-phycoerythrin immunofluorescent FL-2 FL2 FL 2 channels G-protein coupled G protein flow cytometry FC immunofluorescence IF EP1 EP2 EP3 EP4 cAMP smooth muscles mRNA tissues lungs placenta placenta spleen intestines kidneys sensory neurons 30.416372007366
600410 EP4 Receptor (rat) STEP Plate Assay Kit (cAMP method) - 2011-06-28 6.434866482504 ep4-receptor-rat-step-plate-assay-kit-camp-method cell-based assays cells CBAs kits measures measurements prostaglandins E2 PGE2 prostanoids G protein-coupled receptors proteins GPCRs EP1 EP2 EP3 signals transductions mechanisms tissues localizations regulation expression intestines lungs kidneys thymus uterus brains cyclics AMP adenosines monophosphates pathways phosphatidylinositols 3-kinases G1 smooth muscles relaxation gastric secretions intestinal epithelial transportation adrenal aldosterone uterine immunity inflammation human colon cancers colorectal carcinogenesis in vivo neuroprotective excitotoxic injury injuries agonists antagonists therapeutics diseases surface transfections and expression protocols transient technology technologies University of Michigan UM U of M Originus, Inc. USPT United States patents 6897067 6902933 7056741 DNA deoxyribonucleic recombinant proteins cells receptor-mediated endocytosis solution-phase efficiency multiple plasmids constructs intracellular 6.434866482504
10924 Epothilone B 152044-54-7 ≥95% 2011-07-27 21.490939226520 epothilone-b macrolides inhibitors inhibits inhibition tubulin microtubules polymerization cancers cells cycle mitotic arrest mitosis Hs578T HeLa KB3-1 KB31 KBV-1 KBV1 cytoskeletal 21.490939226520
10007806 Epoxomicin 134381-21-8 ≥98% 2008-12-09 57.390685082873 epoxomicin BU 4061T inhibitors inhibits inhibition proteins degradation 20S proteasomes antitumors bones formation Parkinsons diseases anti-tumors 57.390685082873
13184 (±)-Equol 94105-90-5 ≥98% 2009-09-03 6.176095764272 -equol phytoestrogens estrogens daidzen genistein receptors cancers nonsteroidal ERα ERβ ERalpha ER.alpha. ERbeta ER.beta. breast cells proliferation 7,4'-homoisoflavone NV 07α 07alpha 66036-38-2 6.176095764272
10010238 Erbstatin Analog 63177-57-1 ≥98% 2008-06-06 0.437569060774 erbstatin-analog Methyl 2,5-dihydoxycinnamate analogs EGF EGFR inhibitors inhibits inhibition tyrosine kinase DNA synthesis cell cycle proliferation cancers 0.437569060774
10483 Erlotinib 183321-74-6 ≥98% 2010-08-11 27.513535911602 erlotinib Tarceva™; CP 358,774; NSC 718781 tyrosine kinase inhibitor inhibits inhibiting epidermal growth factor receptors EGFR cancers tumor cyclin-dependent cyclin dependent kinase 2 CDK-2 CDK 2 CDK2 JAK-2 JAK2 JAK JAK2V617F CP-358,774 CP-358774 CP 358774 CP358774 CP358,774 NSC-718781 NSC718781 OSI-744 OSI744 R-1415 R1415 R 1415 OSI 744 Quinazolines 27.513535911602
10006329 EUK 134 81065-76-1 ≥98% 2005-03-02 21.421767955801 euk-134 salen manganese SOD ROS catalse stroke oxidative injury porphyrin scavengers peroxynitrites superoxides hydrogen peroxides arteries artery cerebral H2O2 infarct volumes EUK 134 EUK-134 EUK134 21.421767955801
13487 EZH1 Polyclonal Antibody - 2009-07-14 0E-12 ezh1-polyclonal-antibody Western blots WB immunoblotting blotting 0E-12
10022 F16 36098-33-6 ≥98% 12.605414364641 f16 apoptosis induces apoptotic mitochodrial membranes tumors inhibitors fluorescent F-16 cancer inhibits fluorescence lipophilic binding HER-1/EGFR-expressing inhibition cells breast 12.605414364641
10010019 FABP2 Polyclonal Antibody - 2007-10-02 3.441397000789 fabp2-polyclonal-antibody I-FABP; Intestinal-Fatty Acid Binding Protein; Fatty Acid Binding Protein 2 WB western blots fatty acids FABPs lipophilic ligands metabolism polymorphism FABP2 IFABP obesity diabetes antibodies antiserum diabetic antisera atherosclerosis endocrinology blotting immunoblotting 3.441397000789
10010364 FABP5 (human recombinant) - ≥95% 2007-08-08 10.600895027624 fabp5-human-recombinant Keratinocyte FABP; Psoriasis-Associated FABP; Fatty Acid Binding Protein 5; Epidermal-FABP; E-FABP; DA11 FABP proteins lipophilic ligands uptake metabolism cellular membranes FABP-5 FABPs cytosolic fatty acids bladders carcinoma prostates atherosclerosis endocrinology 10.600895027624
10009551 FABP7 (human recombinant) - ≥90% 2007-06-27 2.568988525286 fabp7-human-recombinant B-FABP; Brain-FABP; Fatty Acid Binding Protein 7 cytosolic FABPs amino acids lipophilic ligands tissues metabolism pathways docosahexanoic fatty binding proteins atherosclerosis endocrinology 2.568988525286
10610 F-Amidine (trifluoroacetate salt) Exclusive - ≥95% ✓ 2011-09-23 28.482596685083 f-amidine-trifluoroacetate-salt proteins arginine deiminase 4 PAD4 cancers arthritis inhibitors histones genes expression cysteine PAD1 PAD3 cytotoxic HL-60 MCF7 HT-29 877617-46-4 PADs PAD-1 PAD-3 PAD-4 peptidyl arginine 28.482596685083
10010501 Farnesyl Thiosalicylic Acid 162520-00-5 ≥96% 2008-06-02 18.336316758748 farnesyl-thiosalicylic-acid Salirasib; FTS ras inhibitors inhibition inhibits cancer anti-cancer anticancer prenylation farnesylation signal transduction oncogene atherosclerosis farnesylthiosalicylic acid 18.336316758748
13175 Farnesyl Thiosalicylic Acid Amide Exclusive 1092521-74-8 ≥96% ✓ 2009-02-26 17.489226519336 farnesyl-thiosalicylic-acid-amide Salirasib Amide; FTS Amide Ras degradation cells signaling signalling tumors glioblastoma cancers inhibitors inhibits inhibition 17.489226519336
13287 FK-866 658084-64-1 ≥98% 2009-07-21 68.100817679557 fk-866 K 22.175 nicotinamides phosphoribosyltransferase NAMPT NamPRT PBEF visfatin mononucleotides adenine dinucleotide NAD+ inhibitors inhibitis inhibition cancers apoptosis SIRT1 autophagy FK866 FK 866 K22.175 K 22175 K22175 NamPRT PBEF visfatin carcinoma cells autophagy 68.100817679557
700380 Formaldehyde Assay Kit - 2010-05-14 11.274045898852 formaldehyde-assay-kit CH2O; Methanal HCHO kits assays measures measurements formaldehydes resins cells tissues fluids demethylation/methylation methionine-homocysteines cycles microsomal cytochromes CYP450-dependent oxidations xenobiotics oxidative deamination methylamines semicarbazides amines oxidases SSAO-mediated diabetes diabetic wood kerosene gas cigarettes emissions leukemia nasopharyngeal cancers quantification urine prostate bladder breath breast fluorescence-based acetoacetanilides ammonia fluorescent 11.274045898852
10011269 Fulvestrant 129453-61-8 ≥98% 2009-02-24 23.630331491713 fulvestrant ICI 182,780; Faslodex® estrogen receptors ER ERα agonist antagonist activator breast cancers hippocampus neurons ICI182780 ZD182780 ZD9238 ZM182780 23.630331491713
11332 Fumagillin New 23110-15-8 ≥95% 2012-02-22 0E-12 fumagillin NSC 9168; Amebacilin 297-95-0 47721-00-6 47721-01-7 106215-84-3 746540-00-1 fugillin fumadil B fumagillin fumagillin DCH fumidil microsporidia inhibitors angiogenesis cancers cells growth proliferation genes expression fungus infection infectious diseases adipose tissues obesity Aspergillus fumigatus MetAP2 antibiotics 0E-12
11030 Fumitremorgin C New 118974-02-0 ≥98% 2012-03-30 37.777777777778 fumitremorgin-c Tryptoquivaline 12α-fumitremorgin C cancers multidrug resistance transporters inhibitors inhibition inhibits efflux toxicity breasts proteins BCRP/ABCG2 mitoxantrone doxorubicin topotecan S1-M1-3.2 colon carcinoma cells ABCB1 MRP1 ABCC1 P-glycoproteins fumitremorgin-C 37.777777777778
10353 G9a (human recombinant) - ≥70% 2011-03-08 17.008637329521 g9a-human-recombinant EHMT2; Euchromatic Histone-Lysine N-Methyltransferase 2; KMT1C lysines methylation methyltransferases genes silencing repression proteins recombinants set domain-containing pluripotency H3K9 GLP active 17.008637329521
10755 G9a-like protein (human recombinant) - ≥95% 2011-10-13 18.767345337971 g9a-like-protein-human-recombinant Eu HMTase 1; EHMT1; GLP; Euchromatic Histone-Lysine N-Methyltransferase 1; KMT1D lysine methylation methyltransferase genes silencing repression SET domain histones modifications GLP H3K9 BIX-01294 UNC0638 inhibitors inhibits inhibition SAR monomethylate dimethylate BIX01294 BIX 01294 UNC-0638 UNC 0638 active 18.767345337971
700500 G9a Methyltransferase Inhibitor Screening Assay Kit - 2011-03-10 42.864293560789 g9a-methyltransferase-inhibitor-screening-assay-kit EHMT2 Methyltransferase Inhibitor Screening Assay Kit kits assays measures measurements methylations molecules proteins signals transductions biosynthesis proteins repair genes silencing chromatin regulation S-adenosylmethionine SAM methyltransferases enzymes enzymatic cofactors ATP adenosine triphosphates AdoMet donors methyls groups DNA deoxyribonucleic acids Alzheimer's diseases depression Parkinson's multiple sclerosis livers failures cancers methylations lysines transcriptional activation respression histones functions SET domain-containing mammalian monomethylates dimethylates 9 27 H3 embryogenesis genomic imprinting lymphocytes lung cells HIV-1 H3K9 viral latency GLP G9a-like EHMT1 tumors suppressors p53 373 feedback inhibition methylation reactions 42.864293560789
10008346 Gabapentin 60142-96-3 ≥98% 2006-04-20 3.915138121546 gabapentin Neurontin® antiepileptic drugs Gamma-aminobutyric acids GABA neurotransmitters receptors spinal cord analogs anticonvulsants analgeics neuropathics pain syndromes Complex Regional types CRPS1 multiple sclerosis dysesthesias cancers HIV infections CNS central nervous systems calcium channels .gamma.-aminobutyric g-aminobutyric neurochemistry 3.915138121546
13841 GANT 61 500579-04-4 ≥98% 2011-04-20 70.787052639656 gant-61 NSC 136476 Hedgehog transcription factors genes expression GLI cancer glioblastomas antagonists development regulation GANT61 GANT-61 pyridines pyrimidines NSC136476 NSC-136476 TFs 70.787052639656
10566 Garcinol 78824-30-3 ≥95% 2011-10-25 9.634610820401 garcinol Camboginol inhibits inhibitors inhibition histones acetyltransferases HATs p300 PCAF GCN5 neurogenesis stem cells apoptosis cancers antiinflammatory anti-inflammatory inflammation neuroscience genes expressions regulations epigenetics 9.634610820401
10782 Gcn5 (human recombinant) New - ≥80% 2011-12-05 24.213892198032 gcn5-human-recombinant Lysine acetyltransferase 2A; General control of amino acid synthesis protein 5-like 2; KAT2A; STAF97 epigenetics modifications histones acetylation cancers GNAT N-acetyltransferases enzymes STAGA TFTC SAGA ATAC H3K14 H3K9 H3K18 H4K8 H4K16 H3 H2B KAT2B p300/CBP associated factors Spt-Ada-GCN5-aceytltransferase Ada Two-A containing CoASH Gcn-5 N-acetyltransferases enzymatic subunits complexes proteins active 24.213892198032
13166 Gefitinib 184475-35-2 ≥98% 2010-02-11 21.037874382088 gefitinib Iressa™; ZD1839 EGFR-TK EGFRs TKs epidermal growth factors inhibitors cancers signal transduction tyrosine kinases inhibits inhibited NSCLC Quinazolinones 21.037874382088
13355 Geldanamycin 30562-34-6 ≥98% 2010-07-29 35.265105447297 geldanamycin NSC 122750 NSC 212518 antibiotics heat shock proteins 90 Hsp90 GRP94 gp96 genes expression cells proliferation apoptosis angiogenesis c-jun adenocarcinoma cancers AP-1 steroids receptors 2,5-Cyclohexadiene-1,4-Diones 1,4-Benzoquinones 1,2-Benzoquinones p-Benzoquinones-o-Benzoquinones Benzoquinones Benzodiones Quinones geldanomycin GDM NSC122750 NSC-122750 NSC 122750 AC-6794 BRN 1633093 geldanamicin 30562-34-6 antibiotic U29135 U-29135 U 29135 AC1NQZ81 ligands GRP94 Hsp 90 35.265105447297
11690 Gemcitabine New 95058-81-4 ≥98% 2012-05-23 97.777777777778 gemcitabine LY 188011; NSC 613327; Gemcel; Zefei; GemLip; Folfugem; Gemzar; DDFC nucleosides analogs anticancer non-small cells lungs pancreatic bladder breasts cancers anti-tumor tumors replication repair Gadd45a DNA demethylation antiretroviral AIDS 1239668-67-7 DFdC DFdCyd gamcitabine LY-188011 NSC613327 NSC-613327 LY188011 Gadd45a 97.777777777778
10005167 Genistein 446-72-0 ≥98% 2004-08-04 16.470705954573 genistein isoflavonoids phytoestrogenics legumes glycosides carcinogenic tumors inhibits inhibition inhibitors estrogenic isoflavones uterine DES diethylstilbestrol histones H2B endocrine tyrosine chemopreventitive 16.470705954573
700300 Glucose-6-Phosphate Dehydrogenase Activity Assay Kit - 2011-07-28 112.190172018556 glucose-6-phosphate-dehydrogenase-activity-assay-kit G6PDH kits assays measures measurements Glucose 6 six phosphates Glucose-6-phosphates dehydrogenases cytosolic enzymes catalyzes pentose pathway ribose-5-phosphates precursor RNA ribonucleic acids DNA deoxyribonucleic ATP adenosine triphosphates CoA coenzymes A NAD nicotinamides adenine dinucleotides FAD flavin NADPH phosphates energy cells fatty oxidations lipids biosynthesis substrates oxidases macrophages polymorphonuclear leukocytes oxygen radicals pathogens intracellular metabolic de novo amino red blood RBC mitochondria pentose oxidative damage stress hemolytic anemia neonatal hyperbilirubinemia acute hemolysis chronic X-linked sex-linked hereditary genetics defect mutations G6PD genes malaria Plasmodium falciparum upregulated rat mouse murine obesity hyperglycemia hyperinsulinemia mediator insulin resistance post-translationally preneoplastic lesions tumors suppressors p53 human dimers fluorescence-based erythrocytes lysates tissues homogenates cultures samples 6-phospho-D-gluconate fluorometrics fluorescent 112.190172018556
700750 Glucose-6-Phosphate Fluorometric Assay Kit New - 2012-05-25 77.633420118439 glucose-6-phosphate-fluorometric-assay-kit D-glucose-6-phosphate; Robison ester; G6P assays kits measures measurements cells C6H12O6 hexokinases glucokinases intracellular glycolysis phosphoglucose isomerases cellular energy carbons skeletons biosynthesis glucose-1-phosphates phosphoglucomutases glycogen metabolized dehydrogenases G6PDH NADPH Nicotinamides adenines dinucleotides phosphates hexoses monophosphates reducing nucleic acids precursors de novo pathways amino acids pentoses oxidative damages glutathiones reductases GSH deficiency red blood RBCs stress hemolytic anemias livers enzymes glucose-6-phosphatases storage diseases Type 1 I von Gierke's inherited Ia Ib fasting tolerances hypoglycemias growth retardation hepatomegaly accumulation fats fluorescence-based tissues homogenates culture samples 6-phospho-D-gluconate reduction NADP+ detectors fluorescent 77.633420118439
600450 Glycolysis Cell-Based Assay Kit Exclusive - ✓ 2011-08-18 111.060715804774 glycolysis-cell-based-assay-kit CBAs assays kits measures colorimetric colorimetric-based L-lactate culture media mediums cellular metabolic pathways glucose metabolisms cells ATP adenosines triphosphates oxygen exercise erythrocytes mitochondria glucoeogenesis intracellular molecules amino acids insulin glycolytic neurons aerobic energy muscles anaerobic cancers lactate pyruvate tricarboxylic acids cycles oxidizes carbon dioxide CO2 water H2O tumor aggressiveness embryonic stem activity hypoxia-inducible transcriptional factors HIF-1 extracellular inhibition inhibits inhibitors chemotherapeutic strategies strategy metabolomic drugs discovery anticancer 111.060715804774
10948 GN25 New 1227401-27-5 ≥98% 2011-11-30 135.781546961326 gn25 tumors suppressors p53 cancers K-Ras Snail inhibitors mutations exocytosis cells proliferatiion analogs MKN-45 MKN45 MKN 45 A549 HCT116 GN-25 GN 25 genes humans 2-thio-dimethoxy naphthoquinone binding tumors 135.781546961326
10008886 (+)-Goniothalesdiol Exclusive 204975-45-1 ≥98% ✓ 2009-03-02 0E-12 -goniothalesdiol antitumor gonoiothalaus borneensis leukemia P338 cells tetrahydrofuran 0E-12
10007206 GPR40 Blocking Peptide - 2007-04-12 2.731629834254 gpr40-blocking-peptide immunohistochemistry peptide insulin diabetes breast cancer 2.731629834254
10007205 GPR40 Polyclonal Antibody - 2007-04-04 8.616169429097 gpr40-polyclonal-antibody Free Fatty Acid Receptor; FFAR1; G Protein-Coupled Receptor 40 immunohistochemistry antibody insulin diabetes breast cancer endocrinology IHC 8.616169429097
11569 GSK 1059615 New 958852-01-2 ≥98% 2012-03-15 30.959325890116 gsk-1059615 Phosphatidylinositols PI 3-kinases α PI3Ks PI3Kα PI3Ka PI3K.alpha. inhibits inhibitors inhibition thiazolidinediones cells growth human cancers ATP-competitive p110α p110.alpha. p110a E542K E545K H1047R BT474 tumors xenografts MAPKs signaling biology signals transductions 30.959325890116
10008313 GW 610 872726-44-8 ≥98% 2006-05-10 20.038024861878 gw-610 NSC 721648 antitumors benzothiazoles inhibits inhibitors inhibition cancers antiproliferative isoflavones quercetin genistein cells MCF-7 MDA 468 NCI 60 20.038024861878
10010556 H-89 127243-85-0 ≥98% 2008-07-08 25.158066298343 h-89 5-Isoquinolinesulfonamide; Protein Kinase Inhibitor H-89 inhibitors inhibits inhibition PKA cAMP cell signaling protein kinase S6K1 MSK1 ROCK-II ROCKII PKB.alpha. PKBalpha PKBa MAPKAP-K1b MAPKAPK1b H89 H 89 25.158066298343
10010249 H-8 (hydrochloride) 113276-94-1 ≥98% 2008-07-17 13.932707182321 h-8-hydrochloride Protein Kinase Inhibitor H-8 PKA PKG PKC MLCK cyclin C CDK8 cyclin H CDK7 p36 signal transduction inhibitor inhibits inhibition transcription 84478-11-5 13.932707182321
10010559 HA-1077 (hydrochloride) 203911-27-7 ≥98% 2008-09-03 53.702559852670 ha-1077-hydrochloride Eril; Fasudil; AT-877 protein kinase inhibitors inhibits inhibition ROCK-II ROCKII PRK2 MSK1 MAPKAP-K1b vasodilation hypertension diabetes renal nephropathy cancers 105628-07-7 AT877 AT 877 hydrochloride dihydrochloride monohydrochloride HCl HA1077 HA 1077 53.702559852670
10006515 HAT Inhibitor Screening Assay Kit - 2006-12-06 14.105470800027 hat-inhibitor-screening-assay-kit Histone Acetyltransferase Inhibitor Screening Assay Kit therapeutics histones p300/CBP-Associated Factors pCAF GNAT GCN5-related N-acetyltransferases acetylates lysines N-terminal terminus tails H3 H4 tumors suppressor genes PTEN human cancers apoptosis fluorescence fluorescent inhibitors fluorometric assays 14.105470800027
10576 HC Toxin 83209-65-8 ≥95% 2010-11-10 24.217044198895 hc-toxin Toxin I (Helminthosporium carbonum) inhibitors histones deacetylases HDACs cancers genes regulation regulates regulators epigenetics HC-toxins cell-permable cells permable 15-lipoxygenase-1 15-LO-1 LOs lipoxygenase 15 1 tetrapeptides peptides helminthosporium carbonums cochliobolus maize pathogens Isomerases Amino Acid Acid Isomerases Amino Racemases Amino Acid Amino Acid Isomerases Acid Racemases Amino Amino Acid Racemases 24.217044198895
13504 HDAC11 Polyclonal Antibody - 2009-07-31 0.365911602210 hdac11-polyclonal-antibody Histone Deacetylase 11 wb western immunoblotting HDACs HAT histones antibodies peptides blots blotting 0.365911602210
10009231 HDAC1 (human recombinant) - >10% by SDS-PAGE 2006-12-06 28.775327141220 hdac1-human-recombinant Histone Deacetylase 1 HDAC 1 histones deacetylases enzymes HDACs catalyzes deacetylation nucleosomal nucleosomes transcription factors mediating mediators nuclear receptors co-repressor complexes regulatory pathways E2F TFIIE TFIIF NF-.kappa.B NF-kappaB NF-kB p300 Stat3 p53 retinoblastoma Rb proteins Class I yeast Rpd3 cells lines tissues chromatin structures development differentiation programmed death apoptosis angiogenesis inflammation dysregulation pathogenesis diseases cancers C-terminal C-terminus GST-tagged baculovirus Sf9 active 28.775327141220
10011564 HDAC1 Inhibitor Screening Assay Kit - 2008-04-10 31.288852528686 hdac1-inhibitor-screening-assay-kit HDAC 1 histones deacetylases lysines residues chromatin condensation transcriptional repression fluorescence deacetylation fluorescent inhibits inhibition enzymes license:cyclex fluorometric assays cancer 31.288852528686
13491 HDAC1 Polyclonal Antibody - 2009-07-24 0.306104972375 hdac1-polyclonal-antibody Histone Deactylase 1 HDAC-1 HDACs HDAC 1 antibodies WB western blots HATs immunoblotting blotting 0.306104972375
10009377 HDAC2 (human recombinant) - ≥70% by SDS-PAGE 2006-12-06 23.566802079947 hdac2-human-recombinant Histone Deacetylase 2 HDAC 2 histones deacetylases enzymes HDACs catalyzes deacetylation nucleosomal nucleosomes transcription factors mediating mediators nuclear receptors co-repressor complexes regulatory pathways E2F TFIIE TFIIF NF-.kappa.B NF-kappaB NF-kB p300 Stat3 p53 retinoblastoma Rb proteins Class I yeast Rpd3 cells lines tissues chromatin structures development differentiation programmed death apoptosis angiogenesis inflammation dysregulation pathogenesis diseases cancers C-terminal C-terminus his-tagged baculovirus Sf9 active 23.566802079947
10009232 HDAC3/NCOR2 (human recombinant) - ≥50% 2006-12-06 38.905749309392 hdac3-ncor2-human-recombinant Histone Deacetylase 3 HDAC 3 histones deacetylases enzymes HDACs catalyzes deacetylation nucleosomal nucleosomes transcription factors mediating mediators nuclear receptors co-repressor complexes regulatory pathways E2F TFIIE TFIIF NF-.kappa.B NF-kappaB NF-kB p300 Stat3 p53 retinoblastoma Rb proteins Class I yeast Rpd3 cells lines tissues chromatin structures development differentiation programmed death apoptosis angiogenesis inflammation dysregulation pathogenesis diseases cancers C-terminal C-terminus his-tagged baculovirus Sf9 active 38.905749309392
13493 HDAC3 Polyclonal Antibody - 2009-07-19 9.577400758665 hdac3-polyclonal-antibody Histone Deacetylase 3 HDACs antibodies HATs histones acetyltransferase deacetylases western blotting WB IP immunoprecipation ChIP immunoblots immunoblotting blots 9.577400758665
13494 HDAC4 Polyclonal Antibody - 2009-07-17 0.365911602210 hdac4-polyclonal-antibody Histone Deacetylase 4 WB Western blots immunoblotting IP ChIP antibodies HDACs HATs histones immunoprecipitation blotting 0.365911602210
10009379 HDAC5 (human recombinant) - ≥90% by SDS-PAGE 2006-12-06 32.033977900551 hdac5-human-recombinant Histone Deacetylase 5 HDAC 5 histones deacetylases enzymes HDACs catalyzes deacetylation nucleosomal nucleosomes transcription factors mediating mediators extranuclear receptors co-repressor complexes regulatory pathways E2F TFIIE TFIIF NF-.kappa.B NF-kappaB NF-kB p300 Stat3 p53 retinoblastoma Rb proteins Class IIa yeast Hda 1 catalytic domains amino acids N-terminal N-terminus nucleus cytoplasm cells chromatin structures development differentiation programmed death apoptosis angiogenesis inflammation dysregulation pathogenesis diseases cancers C-terminal C-terminus his-tagged baculovirus Sf9 active 32.033977900551
10009465 HDAC6 (human recombinant) - ≥80% 2007-06-14 22.816166595834 hdac6-human-recombinant GenBank Accession No. BC069243; Histone Deacetylase 6 HDAC 6 histones deacetylases enzymes HDACs catalyzes deacetylation nucleosomal nucleosomes transcription factors mediating mediators nuclear receptors co-repressor complexes regulatory pathways proteins Class II cells lines tissues chromatin structures development differentiation programmed death apoptosis angiogenesis inflammation dysregulation pathogenesis diseases cancers N-terminal N-terminus GST-tagged Sf9 active 22.816166595834
13499 HDAC6 Polyclonal Antibody - 2009-07-14 4.670386740331 hdac6-polyclonal-antibody Histone Deacetylase 6 HDAC-6 HDACs HDAC 6 antibodies WB western blots IP ChIP immunoblotting blotting immunoprecipitation 4.670386740331
13500 HDAC7 (Phospho-Ser155) Polyclonal Antibody - 2009-07-29 0.778358326756 hdac7-phospho-ser155-polyclonal-antibody Histone Deacetylase 7 antibodies MMP AR receptors matrix metalloproteinase androgens Nur77 histones deacetylases N-terminal immunoblotting blots western blotting WB 0.778358326756
19380 HDAC8 (human recombinant) - ≥95% 2009-04-03 20.800361240968 hdac8-human-recombinant HDAC 8 histones deacetylases enzymes HDACs catalyzes deacetylation nucleosomal nucleosomes transcription factors mediating mediators nuclear receptors co-repressor complexes regulatory pathways E2F TFIIE TFIIF NF-.kappa.B NF-kappaB NF-kB p300 Stat3 p53 retinoblastoma Rb proteins Class I yeast Rpd3 cells lines tissues chromatin structures development differentiation programmed death apoptosis angiogenesis inflammation dysregulation pathogenesis diseases cancers C-terminal C-terminus his-tagged baculovirus Sf9 active 20.800361240968
700230 HDAC8 Inhibitor Screening Assay Kit - 2009-05-15 21.721975138121 hdac8-inhibitor-screening-assay-kit Histone Deacetylase 8 Inhibitor Screening Assay Kit histone deacetylases inhibits inhibitors inhibition angiogenesis cycling apoptosis differentiation tumors proliferation anticancers genes epigenetic trichostatin A human class I tissues nucleus cytosolic smooth muscle neuroblastoma pathogenesis kits assays measures measurement fluorescent fluorescence-based 21.721975138121
10009466 HDAC9 (human recombinant) - ≥95% 2007-06-14 16.569378453038 hdac9-human-recombinant GenBank Accession No. NM 178423; Histone Deacetylase 9 histones deacetylases enzymes HDACs catalyzes deacetylation nucleosomal nucleosomes transcription factors mediating mediators nuclear receptors co-repressor complexes regulatory pathways E2F TFIIE TFIIF NF-.kappa.B NF-kappaB NF-kB p300 Stat3 p53 HDAC 9 retinoblastoma Rb proteins Class I yeast Rpd3 cells lines tissues chromatin structures development differentiation programmed death apoptosis angiogenesis inflammation dysregulation pathogenesis diseases cancers C-terminal C-terminus his-tagged baculovirus Sf9 active 16.569378453038
10011563 HDAC Activity Assay Kit - 2008-04-10 45.841554678282 hdac-activity-assay-kit histones deacetylases lysines residues chromatin condensation transcriptional repression fluorescence deacetylation fluorescent inhibits inhibition enzymes license:cyclex fluorometric assays cancer 45.841554678282
600150 HDAC Cell-Based Activity Assay Kit - 2009-11-09 26.370505361597 hdac-cell-based-activity-assay-kit Histone Deacetylase Cell-Based Activity Assay Kit assays kits measuring measurement histones deacetylases lysines residues chromatin condensation transcriptional repression fluorescence deacetylation fluorescent inhibits inhibition enzymes fluorometric assays cancer modulators whole cells proteins lysine-specific HDAC1 homogenous inhibitor/activator TSA 26.370505361597
100024 Hepsin Blocking Peptide (aa 241-260) - 15.781892265193 hepsin-blocking-peptide-aa-241-260 antibodies western blots blotting WB antisera antiserum ICC IHC protease immunohistochemistry immunocytochemistry apoptosis cancer peptides controls 15.781892265193
100022 Hepsin Polyclonal Antibody (aa 241-260) - 13.185718232044 hepsin-polyclonal-antibody-aa-241-260 antibodies western blots blotting WB antisera antiserum protease immunohistochemistry apoptosis IHC cancer formalin fixed paraffin embedded immunoblotting 13.185718232044
10006084 Hesperetin 520-33-2 ≥98% 2005-02-16 18.941703220046 hesperetin hesperitin hesperidin atherosclerosis citrus nutraceuticals flavonoids flavanoids hypocholesterolemic ACAT2 ACAT-2 mRNA transcription inhibits inhibition inhibitors ApoB proteins histamines azelastine atherosclerosis 18.941703220046
16834 Hexadecanal-d5 - ≥99% deuterated forms (d1-d5) 2009-03-02 63.429475138121 hexadecanal-d5 Palmitaldehyde; 16-Hexadecanal deuterated deuterium sphingosine-1-phosphate S1P palmitic acids S1P lyase 1 plasmalogen cell proliferation GC/MS GC-MS LC/MS LC-MS mass spectrometry 63.429475138121
300003 HIF-1α (C-Term) Blocking Peptide - 2005-04-15 60.109337016575 hif-1-c-term-blocking-peptide Hypoxia Inducible Factor 1α HIF-1alpha factors HIF1.alpha. antibodies peptides cancer hypoxia transcription factors low-oxygen hypoxic stimulus cytoplasmic accumulation cells nucleus stress-adaptive proteins oxidative physiology tumors EPAS-1 family phosphorylation prolyl hydroxylases western blotting blots signaling signalling WB controls proteins 60.109337016575
10006421 HIF-1α (C-Term) Polyclonal Antibody - 2005-04-15 71.988411602210 hif-1-c-term-polyclonal-antibody Hypoxia Inducible Factor-1α HIF-1alpha factors antibodies western blots blotting WB antisera antiserum cancers hypoxia transcription factors low-oxygen hypoxic stimulus cytoplasmic accumulation cells nucleus stress-adaptive proteins oxidative physiology tumors EPAS-1 family phosphorylation prolyl hydroxylases immunoblotting HIF1 HIF1alpha HIF1 alpha HIF-1 alpha 71.988411602210
10347 HIF-1α Monoclonal Antibody (Clone H1α67) - 2011-05-09 40.105239410681 hif-1-monoclonal-antibody-clone-h1-67 Hypoxia Inducible Factor-1α WBs western blots IHC immunohistochemistry antibodies HIF-1alpha HIF1a HIF-1a antisera serum cancers H1α67 transcription factors oxidative tumors EPAS-1 EPAS1 EPAS 1 DMOG 2,4-DPD desferrioxamine CoCl2 40.105239410681
10006910 HIF-1α Transcription Factor Assay Kit - 2007-10-31 67.866190607734 hif-1-transcription-factor-assay-kit Hypoxia Inducible Factor-1α tf HIF-1alpha factors HIF1.alpha. cancers basic-helix-loop-helix bHLH cellular oxygen homeostasis cells tissues ischemia infections embryos tumors drugs target breast prostate cardiovascular diseases nuclear extracts whole lysates assays kits ELISAs enzyme-linked immunosorbent double stranded dsDNA HIF1 HIF1alpha HIF1 alpha HIF-1 alpha 67.866190607734
13535 Histone H2A Polyclonal Antibody - 2009-07-31 2.045745856353 histone-h2a-polyclonal-antibody H1 H2B H3 H4 histones antibodies DNA WB western blots immunoblotting ELISA enzyme-linked immunosorbent assays blotting 2.045745856353
13538 Histone H2B (C-Term) Polyclonal Antibody - 2009-08-04 1.047823204419 histone-h2b-c-term-polyclonal-antibody histones antibodiesarginine lysine DNA WB western blots immunoblotting blotting 1.047823204419
13539 Histone H2B (N-Term) Polyclonal Antibody - 2009-08-04 1.047823204419 histone-h2b-n-term-polyclonal-antibody histones antibodies WB western blots immunoblotting DNA arginine lysine blotting 1.047823204419
13540 Histone H3 (Phospho-Ser28) Monoclonal Antibody (Clone 117C826) - 2009-08-10 1.507163904235 histone-h3-phospho-ser28-monoclonal-antibody-clone-117c826 PHH3 H1 H2B H3 H4 histones antibodies WB western blots immunoblotting serine phosphos phosphorylation blotting 1.507163904235
10530 Histone H3 Trimethyl Lys9 Peptide - 2010-06-29 25.162025782688 histone-h3-trimethyl-lys9-peptide H3K9(Me)3 Peptide JMJD2A JMJC JMJD2D acetylation methylation phosphorylation genes transcription substances regulation H3K9Me3 25.162025782688
13543 Histone H4 Polyclonal Antibody - 2009-08-10 0.311850828729 histone-h4-polyclonal-antibody antibodies H1 H2A H2B H3 amino acids WB western blots immunblotting blotting 0.311850828729
11512 HMGB1 Monoclonal Antibody (Clone IMG19N10B7) New - 2012-01-16 0E-12 hmgb1-monoclonal-antibody-clone-img19n10b7 High Mobility Group Protein B1; HMG1 high mobility groups proteins family DNA-binding domains inflammation mediators DNA nuclear bindings sterile infection-associated responses Toll-like receptor 4 TLR4 advanced glycation endproducts RAGE IHC immunohistochemistry Western blot blotting flow cytometry FC WB 0E-12
11514 HMGB1 Monoclonal Antibody (Clone IMG19N12A1) - 0E-12 hmgb1-monoclonal-antibody-clone-img19n12a1 High Mobility Group Protein B1; HMG1 high mobility groups proteins B1 HMGB family DNA-binding domains nuclei nucleus cytoplasm cells mediators inflammation DNA nuclear bindings sterile infection-associated responses Toll-like receptors 4 TLR4 advanced glycation endproducts RAGE WB Western blots blotting 0E-12
11513 HMGB1 Monoclonal Antibody (Clone IMG19N15F4) New - 2012-01-16 0E-12 hmgb1-monoclonal-antibody-clone-img19n15f4 HMG1; High Mobility Group Protein B1 high mobility groups proteins B1 HMGB family nuclei nucleus cytoplasm cells mediators inflammation DNA nuclear binding sterile infection-associated responses Toll-like receptors 4 TLR4 advanced glycation endproducts RAGE WB Western blots blotting flows cytometry FC immunohistochemistry IHC 0E-12
11515 HMGB1 Polyclonal Antibody (aa 100-150) New - 2012-01-20 0E-12 hmgb1-polyclonal-antibody-aa-100-150 HMG1; High Mobility Group Protein B1 high mobility groups proteins B1 HMGB family DNA-binding domains nuclei nucleus cytoplasm cells mediators inflammation DNA nuclear bindings sterile infection-associated responses Toll-like receptors 4 TLR4 advanced glycation endproducts RAGE WB Western blots blotting flows cytometry FC immunohistochemistry IHC 0E-12
11516 HMGB1 Polyclonal Antibody (aa 25-75) New - 2012-01-30 0E-12 hmgb1-polyclonal-antibody-aa-25-75 HMG1; High Mobility Group Protein B1 high mobility groups proteins B1 HMGB family DNA-binding domains nuclei nucleus cytoplasm cells mediators inflammation DNA nuclear bindings sterile infection-associated responses Toll-like receptors 4 TLR4 advanced glycation endproducts RAGE WB Western blots blotting 0E-12
13295 HNHA 926908-04-5 ≥98% 2009-09-03 23.011531893520 hnha Histone Deacetylase Inhibitor VI inhibitors inhibits inhibition histones deacetylase HDACs cancers fibrosarcoma HT1080 cells hyperacetylation p21 genes expressions transcription cycles arrest tumor growth murine xenograph human umbilical vein endothelial HUVECs tubes formation migration vascular endothelial factors VEGF retinal neovascularization angiogenesis 23.011531893520
11235 HP1-α (human recombinant) New - ≥95% 2012-05-03 81.581588704727 hp1-human-recombinant Chromobox Homolog 5; Heterochromatin Protein 1-α; CBX5; Antigen p25 epigenetics heterochomatin chromodomains histones H3K9 Chromoshadow domain HP-1 HP1α HP1 α HP1s HP1β HP1ɣ hinge domain SETDB1 methylation homodimerization DNA damage response DDR 81.581588704727
10011384 Hsc70 (Hsp73) Polyclonal Antibody - 2008-03-26 0.427255985267 hsc70-hsp73-polyclonal-antibody Heat Shock Cognate 70 heat shock stress protein antibodies antiserum WB immunoblotting western blots immunoprecipation immunofluorscence IP IF blotting 0.427255985267
10011383 Hsp40 Polyclonal Antibody - 40 kDa 2008-03-26 0.400552486187 hsp40-polyclonal-antibody Heat Shock Protein 40; HDJ1 DnaJ WB translation folding unfolding translocation degradation heat shock stress chaperone antibodies antiserum Hsps immunoblotting western blots blotting 0.400552486187
10202 Hsp90α (human recombinant) - ≥80% 2010-03-16 5.324861878452 hsp90-human-recombinant Hsp86; Heat Shock Protein 90α heat shock proteins molecular chaperones Hsp90.alpha. Hsp90AA1 HspCAL4 HspN 90kDa cytosolic class A member 2 heat-shock 1 Hsp90AA2 Hsp86 Hsp90a active 5.324861878452
10342 Hsp90β (human recombinant) - ≥85% 2010-03-16 4.351576210594 hsp90-human-recombinant Hsc90; Heat Shock Protein 90β; Hsp90 AB1 heat shock proteins molecular chaperones Hsp90.beta. 90kDa alpha cytosolic class B member 1 Hsp90beta Hsp90AB1 Hsp90b active 4.351576210594
10005673 HU-331 137252-25-6 ≥95% 2005-09-09 39.848813177818 hu-331 cannabidiols analogs antiproliferative activity endocannabinoids central CB1 peripheral CB2 non-CB receptor-mediated pharmacology receptors memory weight loss appetite neurodegeneration tumor surveillance analgesia inflammation hydroxylquinone antineoplastic human cancer cells lines inhibits inhibitors inhibition growth Raji Jurkat lymphomas in vitro HT-29 colon carcinomas neuroscience neurochemistry cannabinoids cbs sythetic 39.848813177818
13624 Icariin 489-32-7 ≥97% 2010-02-11 1.115469613259 icariin PDE5 inhibitors flavonoids differentiation cancers proliferation flavonols E brevicornum horny goat weed BMP2 ED erectile dysfunction 2-Phenyl-Benzopyrans 2 Phenyl Benzopyrans 2-Phenyl-Chromenes 2 Phenyl Chromenes Bioflavonoids Flavonoids 1.115469613259
10008207 IGFBP5 Polyclonal Antibody - 2007-07-19 22.348637200737 igfbp5-polyclonal-antibody IGF-Binding Protein 5; IBP-5; Insulin-like Growth Factor Binding Protein 5 IGF-1 cell growth differentiation apoptosis receptors kidney heart placenta skeletal cancers amino acids neuroblastoma mammary glands antibodies wb western blots immunocytochemistry IGF1 IGFBP-5 endocrinology blotting immunoblotting 22.348637200737
13139 Imatinib (mesylate) 220127-57-1 ≥98% 2009-04-21 41.939928966061 imatinib-mesylate CGP57148B; Glivec; Gleevec; STI-571 inhibitors tyrosine kinase cancer chronic myelogenous leukemia CML c-ABL kits c-kit platelet-derived growth factor receptors imatinib mesilate 152459-95-5 75-75-2 gleevec 41.939928966061
11572 IOX1 New 5852-78-8 ≥97% 2012-05-09 95.770095150398 iox1 hypoxia 2-oxoglutarate Fe 2OG ferrous iron-dependent oxygenases collagen histones demethylation inhibitors inhibits inhibition H3K9me3 JMJD2A JMJD2E enzymes lipids metabolism nucleic acid diseases cancers oxygenases PHF8 PHD2 FIH 95.770095150398
10739 Isoliquiritigenin 961-29-5 ≥98% 2011-04-01 50.434276243093 isoliquiritigenin ISL; GU 17 antioxidants flavonoids chemoprevention quinones reductase-1 reductase1 hepatoprotection hepatoma cells flavanoids 50.434276243093
13325 Iso-Olomoucine 101622-50-8 ≥98% 2011-07-27 0.331546961326 iso-olomoucine cyclin dependent kinases Cdks cells cycles dopamine inhibitors inhibits inhibition inactive controls regulators iso olomoucine transporter diseases neurodegenerative signaling rats dorsal striatal synaptosomes cancers neuroscience 0.331546961326
13288 Itraconazole 84625-61-6 ≥95% 2011-02-22 26.258240868630 itraconazole hedgehogs signaling cancer antifungal inverse agonist patched smoothened Canditral Cladosal 100 Itralek Itrizole Oriconazole Orungal R 51211 Sempera Spherazole CR IR Sporal Sporamelt Sporanox Sporonox Traconal Triasporin Janssen-Cilag Brand of Itraconazole Janssen Cilag Brand of Itraconazole Janssen Brand of Itraconazole Itraconazole Janssen Brand Itraconazole Sporanox R-51211 R 51211 Orungal R51211 26.258240868630
13659 IWR-1-endo 1127442-82-3 ≥98% 2010-03-23 21.186758747697 iwr-1-endo Wnt cancers embryonic developments tissues homeostasis embryogenesis tumorigenesis stem cells β-catenin genes expression transcription inhibitors inhibits inhibition proteasomes Apc Axin2 Ck1 Gsk3β IWR-1-exoendo-1,3(4)-beta-D-glucanase Endo-1,3(4)-beta-Glucanase Endo-1,3(4)-B-Glucanase beta-(1-3,1-4)glucanase 21.186758747697
13598 IWR-1-exo 1127442-87-8 ≥98% 2010-03-23 16.155635359116 iwr-1-exo Wnt cancers embryonic developments tissues homeostasis embryogenesis tumorigenesis stem cells β-catenin genes expressio Cellobiohydrolase, 1,4-beta-D-Glucan 1,4-beta-D-Glucan Cellobiohydrolase 1,4 beta D Glucan Cellobiohydrolase 1,4-beta-Cellobiosidase, Cellulose Cellulose 1,4-beta-Cellobiosidase Cellulose 1,4 beta Cellobiosidase Beta-Glucancellobiohydrolase Beta Glucancellobiohydrolase Exo-Cellobiohydrolase Exo Cellobiohydrolase Cellobiohydrolase II Cellobiohydrolase I Cellobiohydrolase A Cellobiohydrolase Exoglucanase II CEL1 Protein CbhI Proteinn transcription inhibitors inhibits inhibition controls 16.155635359116
10011246 Janex 1 202475-60-3 ≥98% 2008-12-17 0.861878453039 janex-1 WHI-P131 inhibitors inhibits inhibition JAK3 apoptosis leukemias anti-inflammatory antiinflammatory lymphocytes WHIP131 Janex 1 0.861878453039
9000059 (±)-Jasmonic Acid methyl ester 39924-52-2 ≥95% (mixture of isomers) 2009-04-01 6.891955801105 -jasmonic-acid-methyl-ester (±)-Methyl Jasmonate cancers plants apoptosis survival inflammation hexokinase jasmonic acids jasmonates stress hormones proteins inhibitors inhibition inhibited mitochondrial hexokinase anti-inflammatory 6.891955801105
10009172 JC-1 Mitochondrial Membrane Potential Assay Kit - 2007-04-12 167.858463696725 jc-1-mitochondrial-membrane-potential-assay-kit apoptosis cells mitochondria caspases cytochrome C electrons transport transmembranes Dym DELTApsim .DELTA..psi.m fluorscence fluorescent cationic dyes rhodamine-123 Rh123 DiOC6 cytofluorimetric lipophilic tetrachloro-1,1',3,3'-tetraethylbenzimidazoylcarbocyanine iodide green red J-aggregates monomeric assays kits measures measurements microscopy flow cytometry plate readers fluorometric cancer JC1 cell-based assays cell based assay cba JC 1 167.858463696725
10641 JGB1741 Exclusive 1256375-38-8 ≥98% ✓ 2011-06-20 17.811325966850 jgb1741 ILS-JGB-1741 inhibitors SIRT1 breasts cancers cells proliferation apoptosis p53 histones acetylation genes energy homeostasis regulation deacetylases sirtuins NAD+ inhibits inhibition SIRT2 SIRT3 ILS JGB 1,741 1741 SIRTs JGB-1741 JGB-1,741 17.811325966850
10336 JMJD2A (human recombinant) - ≥95% 2010-12-01 17.414083026396 jmjd2a-human-recombinant JHDM3A; KDM4A; Jumonji Domain Containing 2A lysine (K)-specific demethylase 4A Epigenetics Histone Demethylase chromatin regulator dioxygenase JmjC active 17.414083026396
700360 JMJD2A Inhibitor Screening Assay Kit - 2010-05-25 19.047282813814 jmjd2a-inhibitor-screening-assay-kit Jumonji Domain Containing 2A Inhibitor Screening Assay Kit kits assays measures measurements histones nucleoproteins chromatins DNA deoxynucleic acids eukaryotic nucleus nucleosomal H3 H4 H2B H2A octamers amino termini acetylation phosphorylation ubiquitination methylation replication repair transcriptional activation repression dysregulation tumors suppressor genes cancers inhibitors enzymes catalyzes epigenetic marks methyls lysines arginines residues demethylases 1 JMJC JHDM1 JHDM2 JHDM3 JARID1 UTX/UTY cupin 2-oxoglutarate 2OG iron Fe(II) oxygenases hydroxylation JMJD2A JMJD2B JMJD2C JMJD2D JMJD2E JMJD2F fluorescence-based fluorescent cells lysates formaldehydes peptides substrates oxidation/decarboxylation acetoacetanilides ammonia H3K9(Me)3 trimethylated 19.047282813814
11299 JMJD2A-Strep tagged (human recombinant) Exclusive New - ≥95% ✓ 2012-05-08 110.723606945540 jmjd2a-strep-tagged-human-recombinant KDM4A; Jumonji Domain Containing 2A; JHDM3A JMJD2A Jumonji domain demethylase epigenetics FDH KDM4Atrimethylllysine-specific JmjC protein hydroxylase Strep-Tactin StrepTactin Strep Tactin 110.723606945540
10335 JMJD2D (human recombinant) - ≥75% 2011-02-09 15.302862014869 jmjd2d-human-recombinant Jumonji Domain Containing 2D; KDM4D; Lysine-Specific Demethylase 4D epigenetics histones demethylases chromatin regulators dioxygenases JmjC proteins jumanjis active 15.302862014869
700370 JMJD2D Inhibitor Screening Assay Kit - 2010-05-25 19.603553147282 jmjd2d-inhibitor-screening-assay-kit Jumonji Domain Containing 2D Inhibitor Screening Assay Kit kits assays measures measurements histones nucleoproteins chromatins DNA deoxynucleic acids eukaryotic nucleus nucleosomal H3 H4 H2B H2A octamers amino termini acetylation phosphorylation ubiquitination methylation FLJ10251 replication repair transcriptional activation repression dysregulation tumors suppressor genes cancers inhibitors enzymes catalyzes epigenetic marks methyls lysines arginines residues demethylases 1 JMJC cupin 2-oxoglutarate 2OG iron Fe(II) oxygenases hydroxylation JMJD2A JMJD2B JMJD2C JMJD2D JMJD2E JMJD2F fluorescence-based fluorescent cells lysates formaldehydes peptides substrates oxidation/decarboxylation acetoacetanilides ammonia H3K9(Me)3 trimethylated 19.603553147282
11300 JMJD2D-Strep tagged (human recombinant) Exclusive New - ≥70% ✓ 2012-05-08 113.753599052880 jmjd2d-strep-tagged-human-recombinant KDM4D; Lysine-specific Demethylase 4D; Jumonji Domain Containing 2D JMJD2D Jumonji domain demethylase epigenetics FDH KDM4D JmjC proteins hydroxylase Strep Tactin StrepTactin Strep-Tactin 113.753599052880
11237 JMJD2E-Strep tagged (human recombinant) Exclusive New - ≥75% ✓ 2012-05-08 124.786284837323 jmjd2e-strep-tagged-human-recombinant Jumonji Domain Containing 2E; KDM4D-Like JMJD2D Jumonji domain demethylase epigenetics FDH KDM4D JmjC protein hydroxylase Strep-Tactin Strep Tactin StrepTactin KDM4DL 124.786284837323
10008131 JNJ-10198409 627512-69-0 ≥98% 2006-10-18 16.361977900553 jnj-10198409 PDGF-BB tyrosine kinases inhibits inhibition inhibitors growth factors receptors platelet-derived antiangiogenic antiproliferative coronary artery smooth muscle cells antagonists ATP binding hydrolysis tumors angiogenesis 16.361977900553
11511 JNK2 Polyclonal Antibody - 2011-11-18 0E-12 jnk2-polyclonal-antibody SAPK1a; p54a; c-Jun Amino Terminal Kinase 2; MAPK9 antibody c-Jun kinases JNKs MAP phosphorylation JNK1 JNK3 nuclear signals transduction proteins transcription factors p53 Western blots WB blotting JNKs JNK-1 JNK-2 JNK-3 0E-12
11232 (−)-JQ1 Exclusive New 1268524-71-5 ≥98% ✓ 2012-04-23 107.848419726214 -jq1 BET bromodomain inhibitors inhibits inhibition BRD4 BRD2 transcription cancers extra terminal domains proteins BRD3 cells inflammatory inflammation genes expression mitosis viral viruses histones chromatin JQ 1 JQ-1 (±)-JQ1 ±-JQ1 107.848419726214
11187 (+)-JQ1 Exclusive New 1268524-70-4 ≥98% ✓ 2012-04-23 220.321955079750 -jq1 BET bromodomain inhibitors inhibits inhibition BRD4 BRD2 transcription cancers JQ-1 JQ 1 extra terminal domains BRD3 cells genes expression inflammatory inflammation viral viruses mitosis histones chromatin (±)-JQ1 ±-JQ1 10741 220.321955079750
10009458 JTE-013 383150-41-2 ≥98% 2007-01-18 70.191724984653 jte-013 reverses inhibition inhibits coronary artery smooth muscles lipids cells proliferation cytoskeletal morphogenesis GPCRs protein-coupled receptors antagonists S1P2 humans rats EDG5 sphingosines sphingosine-1-phosphates sphingosine1 inhibitors JTE013 FDG-5 cancers 70.191724984653
10879 JW 480 - ≥98% 2011-07-18 0.874254143646 jw-480 inhibitors lipids mediators inhibitors inhibits inhibition KIAA1363 KIAA 1363 KIAA-1363 JW480 JW-480 AADACL1 MAGE monoalkylglycerols ether neutral ether lipids NEL prostate cancers hydrolases 0.874254143646
10010239 Kenpaullone 142273-20-9 ≥98% 2007-09-04 13.485745856354 kenpaullone NSC 664704; 9-Bromopaullone GSK-3.beta. cyclin-dependent kinase cyclin CDK inhibitors inhibits inhibition proliferations cell cycle cancers 13.485745856354
10012659 Ki16425 355025-24-0 ≥95% 2008-11-06 118.064818907305 ki16425 LPA1 LPA2 LPA3 LPA4 LPA5 lysophosphatidic acids cancers antagonist receptors selective 118.064818907305
10640 KM 233 Exclusive 628263-22-9 ≥98% ✓ 2011-07-07 30.745445845929 km-233 KM233 KM-233 CBs cannabinoids CB2 agonists recptors CB1 gliomas anti tumors cancers 30.745445845929
11208 KRN 7000 New 158021-47-7 ≥98% 2012-03-30 41.476023391813 krn-7000 immunology cancers lupus diabetes malaria tuberculosis NKT cells GalCer α-galactosylceramide KRN7000 KRN-7000 AGL582 AGL 582 synthetic immune tumors autoimmune 41.476023391813
10011011 KT 5720 108068-98-0 ≥98% 2009-01-20 131.231846882399 kt-5720 PKAs cAMPs signaling proteins kinase inhibitors inhibits inhibition phosphorylase kinase PDK1 MEK MSK1 PKα GSK3β KT5720 KT-5720 131.231846882399
11305 Kynurenine New 2922-83-0 ≥98% 2012-02-27 3.048518081679 kynurenine 3-anthraniloyl-Alanine typtophan pathways catabolism glioma typtophan-2,3-dioxygenase tumors AhR aryl hydrocarbons receptors quinolinic acid neurodegenerative diseases L-Kynurenine 3-anthraniloyl-alanine kynurenin 3.048518081679
10010329 Lavendustin C 125697-93-0 ≥98% 2008-07-08 11.503353591160 lavendustin-c HDBA; NSC 666251 EGFR kinases tyrosine pp60c-src pp60csrc CamKII SOD neutrophil activation erbstatin inhibitor inhibits inhibition Lavendustin-C 11.503353591160
10008882 LDH Cytotoxicity Assay Kit - 2006-12-15 257.957353395323 ldh-cytotoxicity-assay-kit Lactate Dehydrogenase Cytotoxicity Assay Kit cells death apoptosis necrosis measuring measurement cystolic enzymes cells membranes integrity cancer cell-based assays cell based assay cba 257.957353395323
10010265 LFM-A13 244240-24-2 ≥98% 2008-01-23 1.796721915285 lfm-a13 BTK Bruton's Tyrosine kinases signal transduction leukemia cancers polo-like anti-cancer chemosensitivity apoptosis CD95 1.796721915285
10245 LSD1 (human recombinant) - ≥50% 2009-06-03 5.453445769118 lsd1-human-recombinant AOF2; NPAO; Lysine-Specific Demethylase 1; BHC110; p110b; KDM1 recombinant humans E.coli histones tumors suppressor CoREST lysine specific demethylase 1 proteins enzymes active 5.453445769118
700120 LSD1 Inhibitor Screening Assay Kit - 2008-10-16 24.063191420214 lsd1-inhibitor-screening-assay-kit Lysine-Specific Demethylase 1 lysines 4 demethylases histones residues repression transcription chromosomal DNA chromosomes inhibits inhibitors inhibition tumors suppressors activity cells cycles progression cancers fluorescent fluorescence enzymes enzymatic reactions H2O2 hydrogens peroxides peptides N-terminal tails H3 horseradish peroxidases ADHP resorufins assays 24.063191420214
13554 LSD1 Polyclonal Antibody (aa 100-150) - 2009-08-10 0.158195211786 lsd1-polyclonal-antibody-aa-100-150 Amine Oxidase (flavin containing) Domain 2 WIRM N-terminal antibodies WB western blots immunoblotting CoREST histones HDACs LSD1 AOF2 amine oxidase flavin containing domain 2 peptide affinity blotting 0.158195211786
13553 LSD1 Polyclonal Antibody (aa 400-450) - 2009-08-10 0.158195211786 lsd1-polyclonal-antibody-aa-400-450 antibodies WB western blots immunoblotting lysine histones demethylase FAD-binding SWIRM domains blotting 0.158195211786
13486 LSD1 Polyclonal Antibody (aa 450-500) - 2009-08-11 0.135595895816 lsd1-polyclonal-antibody-aa-450-500 WIRM N-terminal antibodies WB western blots immunoblotting CoREST histones HDACs LSD1 blotting 0.135595895816
13555 LSD1 Polyclonal Antibody (aa 800-850) - 2009-08-13 0.158195211786 lsd1-polyclonal-antibody-aa-800-850 WIRM N-terminal antibodies WB western blots immunoblotting CoREST histones HDACs LSD1 immunohistochemistry IHC paraffin AOF2 amine oxidase flavin containing domain 2 blotting 0.158195211786
10007502 Luminex® Thromboxane B2 Kit - 2009-07-13 37.424419889502 luminex-thromboxane-b2-kit Luminex® TXB2 Kit thromboxanes thromboxane A2 TXA2 metabolites urine in vivo measures kits luminex xMAP beads assays 37.424419889502
11215 Lupeol New 545-47-1 ≥98% 2012-02-15 22.361170100521 lupeol NSC 90487; Monogynol B; Fagarasterol; β-Viscol; Lupenol; Clerodol AC-1371 AC1371 AC 1371 132473-92-8 200123-55-3 fagarsterol dietary triterpenes anti-inflammatory anticarcinogenic antimutagenic antimaralia fruits vegetables medicinal plants antimalarial cells carcinoma cancers SMMC7721 SMMC-7721 SMMC 7721 HepG2 melanoma mel928 mel-928 mel 928 mel1241 mel-1241 mel 1241 blood pressure strokes hypertension rats genes cholesterol synthesis neutrophils monogynol B NSC-90487 NSC90487 beta-viscol b-viscol 22.361170100521
10009768 LY293111 Exclusive 161172-51-6 ≥98% ✓ 2009-02-09 62.413743093923 ly293111 Etalocib; VML 295 LTBs LTB4 receptors inflammation antagonist benzophenone neutrophil chemotaxis pancreatic cancers 62.413743093923
13341 LY364947 396129-53-6 ≥98% 2009-07-23 57.630497237569 ly364947 TGF-β RI Kinase Inhibitor; HTS 466284 TGF-β receptor inhibitors antagonists Smad p38 MAPK MLK-7 cells growth fibroblasts NIH 3T3 cells phosphorylation fibronectin PAI-1 uPA matrigel invasion MDA-MB-231 cells transforming factors LY 364947 LY-364947 HTS-466284 HTS466284 HTS 466284 ALK5 Inhibitor I TβR-I inhibitor Transforming Growth Factor-β Type I Receptor Kinase Inhbitor [3-(Pyridin-2-yl)-4-(4-quinoynyl)]-1H-pyrazole 57.630497237569
600310 Lysosome/Cytotoxicity Dual Staining Kit - 2010-06-15 45.912119179162 lysosome-cytotoxicity-dual-staining-kit lysosomes membrane-bound acidic intracellular compartments cells waste products fats carbohydrates proteins macromolecules mobilize recycle organelles microorganisms animals leukocytes degradative enzymes hydrolases pH 5 cytoplasm homeostasis Tay-Sachs diseases arthritis neurodegeneratives Parkinson's brains cathepsin D genes therapeutics kits assays measures measurements 4-Nitro-7-(1-piperazinyl)-2,1,3-benzoxadiazole NBD-PZ membranes permeable carboxylic acids luminal cultured propidium iodides death chloroquine inhibitors positive controls fluorescence fluorescent microscopy plates reader detections flow cytometry 45.912119179162
13174 M 344 251456-60-7 ≥98% 2009-07-24 25.973145718231 m-344 D237; Histone Deacetylase Inhibitor III; MS 344 HDACs inhibitors inhibits inhibitions histones deacetylases HDAC1 HDAC6 cancers squamous carcinoma radiation cells cycles arrest apoptosis endometrial ovarian M344 MS344 M-344 MS-344 25.973145718231
10010497 Manumycin A 52665-74-4 ≥98% 2008-06-25 16.571464088398 manumycin-a UCF 1C; NSC 622141 farnesyltransferase inhibitors inhibits inhibition cancer antitumor anti-tumor signal transduction Ras farnesylation NF-.kappa.B NF-kB NF-kappaB 16.571464088398
10009645 Maslinic Acid Exclusive 4373-41-5 >98% ✓ 2007-11-02 16.165856353591 maslinic-acid 2α-Hydroxyoleanoic Acid; Crategolic Acid cancer apoptosis antiproliferative antioxidant HIV inhibition inhibitor inhibits leukemia cells astrocytoma CaCo-2 colon HIV-1 aids 16.165856353591
10005174 Matairesinol 580-72-3 ≥95% 2004-07-28 176.798646408839 matairesinol lignans plants antioxidants cancer oxidative injury stress enterobacterial fiber dietary enteric isoprostanes enterolactone 176.798646408839
11286 MBD2 (human recombinant; methyl binding domain aa 150-220) New - ≥95% 2012-03-27 105.630555555555 mbd2-human-recombinant-methyl-binding-domain-aa-150-220 Methyl Cytosine Binding Domain 2; Methyl-CpG Binding Domain Protein 2 Methyl CpG binding domains genes expression DNA chromatin MBD epigenetics CpG islands methylation MBDs 5-methylcytosine 5mC breast cancer tumors 105.630555555555
11287 MeCp2 (human recombinant; methyl binding domain aa 77-166) New - ≥95% 2012-04-20 105.630555555555 mecp2-human-recombinant-methyl-binding-domain-aa-77-166 Methyl-CpG Binding Protein 2 Methyl CpG binding domains genes expressions DNA chromatin MBD epigenetics CpG islands MBDs 5-methylcytosine 5mC neurological Rett Syndrome MeCp-2 protein 105.630555555555
13847 MEK2 Polyclonal Antibody - 2010-11-18 0E-12 mek2-polyclonal-antibody MAPKK2; MAP Kinase Kinase 2; Dual Specificity MAP Kinase Kinase 2; MAP Kinase/ERK Kinase 2 MEKs MEK-2 MEK2 MAPKs kinases MAP ERKs phosphorylation antibodies serine cytokines growth factors tranduction mitogenic signals western blots blotting immunoblotting 0E-12
13778 Metastasis Associated 1 Family Member 2 Polyclonal Antibody - 2010-05-04 8.700276243093 metastasis-associated-1-family-member-2-polyclonal-antibody p53 Target Protein in Deacetylase Complex; MTA2; MTA-L1 Protein; PID WB IHC western blotting blots immunoblotting immunohistochemistry MTA-2 MTA 2 MTA-1 MTA 1 MTA-3 MTA 3 HDAC2 HDAC-2 HDAC 2 HDAC1 HDAC-1 HDAC 1 proteins chromatin deacetylase activity activities northern p53 8.700276243093
9000332 Methylcarbamyl PAF C-8 Exclusive - ≥98% ✓ 2009-02-25 11.841353591160 methylcarbamyl-paf-c-8 Methylcamyl PAF Methylcamyl PAF C-8 Methylcamyl PAF C-16 PAF C-16 PAF-AH Platelet aggregation c-myc c-fos MAP kinase Mitogen-activated kinase G1 Cell cycle PAF 11.841353591160
700140 Methyltransferase Colorimetric Assay Kit - 2009-04-07 30.225331001137 methyltransferase-colorimetric-assay-kit MT Colorimetric Assay Kit assays kits measures measuring monitoring monitors MTs methylation signal transduction biosynthesis repair gene silencing chromatin regulation S-adenosylmethionine SAM-dependent methyltransferases enzymatic cofactors AdoMet donor modifications DNA Alzheimer's diseases depression Parkinson's multiple sclerosis liver failure cancers enzyme-coupled AdoHcy positive control S-adenosylhomocysteine 30.225331001137
700150 Methyltransferase Fluorometric Assay Kit - 2009-04-08 26.105699252585 methyltransferase-fluorometric-assay-kit MT Fluorometric Assay Kit assays kits measures measuring monitoring monitors MTs methylation signal transduction biosynthesis proteins repair gene silencing chromatin regulation S-adenosylmethionine SAM-dependent methyltransferases enzymes enzymatic cofactors AdoMet donor proteins modifications DNA Alzheimer's diseases depression Parkinson's multiple sclerosis liver failure cancers enzyme-coupled AdoHcy positive control S-adenosylhomocysteine 26.105699252585
10007188 Microcystin-LR 101043-37-2 >95% 2005-07-20 21.793232044199 microcystin-lr Cyanoginosin-LR proteins phosphatases inhibitors microcystins toxins hepatotoxic cyclics heptapeptides cyanobacteria poisonings humans livestock fresh water blue-green algae endemic PP-2A inhibits enzymes PP-1 serine/threonine nodularins okadaic acids 21.793232044199
10006317 Mifepristone 84371-65-3 >98% 2005-01-25 108.466239147593 mifepristone RU-486 progesterones estrogens estradiol cancers apoptosis RU486 uterine uterus pregnancy hormones receptors glucocorticoids steroids PR GR HRE response elements binding endocrinology 108.466239147593
63280 Miltefosine 58066-85-6 >98% 7.599502762431 miltefosine HePC CTP:phosphocholines cytidylyl transferases antimetastatic ceramides apoptosis inhibits inhibitors inhibition cancers 7.599502762431
13208 Mirin 299953-00-7 ≥95% 2009-04-15 42.463867403315 mirin DNA damage ATM histone nuclease MRN Mre11 Rad50 Nbs1 repair 42.463867403315
11434 Mithramycin A New 18378-89-7 ≥98% 2012-05-01 73.940322283609 mithramycin-a A 2371; Antibiotic LA 7017; PA 144; NSC 24559; Plicamycin; Aureolic Acid 1395-17-1 1403-98-1 12708-66-6 12708-67-7 23973-19-5 97666-60-9 219612-19-8 744999-90-4 807260-73-7 826336-23-6 899900-19-7 1195235-16-5 mithracin NSC-24559 NSC24559 PA144 PA-144 A2371 A-2371 plicatomycin anti-tumors neuroprotective antibiotics chemotherapeutics histones acetylation transcription factors chromatin regulation Sp1 inhibitors inhibits inhibition oncogene TRAIL cancers Streptomyces grieseus S. grieseus DNA apoptosis 73.940322283609
11435 Mitomycin C New 50-07-7 ≥98% 2012-04-19 76.146300654835 mitomycin-c Mitonco; NSC 26980; Mitoplus; Ametycine; MMC; MitoExtra mitocin C NSC-26980 NSC26980 7481-68-7 74349-48-7 144085-53-0 antitumor antibiotics alkylating agents DNA crosslinkers antiproliferative synthesis genetics recombination repair chemotherapy wounds healing glaucoma tumors NADH cytochromes Streptomyces caespitosus genes mutagenensis cornea ophthalomology mito-extra mutamycin mytomycin kyowa S 76.146300654835
10658 MLL1 (human recombinant) New - ≥95% 2011-12-21 0.478496503496 mll1-human-recombinant Lysine Methyltransferase 2A; ALL1; Mixed Lineage Leukemia 1; HRX; KMT2a epigenetics methyltransferase histones H3K4 genes regulations MLL proteins complex subunits Ash2L WDR5 RbBP5 DPY30 mixed lineage leukemia methylation lysine HOX Pol II WAR c-terminal SET1 WIN binds binding DPY-30 WARD genomic 0.478496503496
10756 MLL1/WAR complex (human recombinant) New - ≥90% 2012-01-04 14.152052839174 mll1-war-complex-human-recombinant Mixed-Lineage Leukemia-1; MLL Core Complex epigenetics methyltransferases histones H3K4 genes regulations MLL proteins complex subunits Ash2L WDR5 RbBP5 DPY-30 upregulate transcriptions catalytic basal RNA polymerases chromosomes Pol II N-terminus leukemia Hox menin active 14.152052839174
10945 MLL1/WARD complex (human recombinant) New - ≥90% 2012-01-04 16.762033767337 mll1-ward-complex-human-recombinant Mixed-Lineage Leukemia-1; KMT2A; MLL Core Complex epigenetics methyltransferases histones H3K4 genes regulations MLL proteins complex subunits Ash2L WDR5 RbBP5 DPY-30 upregulate transcriptions catalytic basal RNA polymerases chromosomes Pol II N-terminus leukemia Hox menin WAR active 16.762033767337
10011389 Mn SOD (rat) Polyclonal Antibody - 2008-03-27 139.066901054746 mn-sod-rat-polyclonal-antibody Manganese Superoxide Dismutase SOD1 SOD2 SOD3 EC-SOD oxidative stress superoxide ROS WB IP IHC EIA western blots immunoprecipitation immunohistochemistry immunoblotting blotting enzyme immunoassays 139.066901054746
10212 Monoacylglycerol Lipase (FL) Polyclonal Antibody - 2010-03-23 37.858350434096 monoacylglycerol-lipase-fl-polyclonal-antibody MAGL; MGL WB western blots hydrolases antibodies antiserum antisera hydrolysis immunohistochemistry IHC immunoblotting MGL monoacylglycerol neuroscience neurochemistry MAGL monoglycerol blotting 37.858350434096
10004910 Mouse Macrophage Microsomal Immunoblot Control - 2004-11-09 31.015125844076 mouse-macrophage-microsomal-immunoblot-control Mouse macrophage microsomes protein western blots blotting microsomes immunoblots immunoblotting positive controls COX-2 COX2 PGHS-2 PGHS2 cyclooxygenases prostaglandins synthases cultures SDS-PAGE 31.015125844076
13284 MS-275 209783-80-2 ≥98% 2009-11-05 37.997177716390 ms-275 Entinostat; SNDX 275 inhibitors histone deacetylases HDACs HDAC1 HDAC3 HDAC8 cyclin-dependent kinase inhibitor 1A p21 CIP1 WAF1 cell growth differentiation tumors cancers apoptosis adriamycin PARP Hsp90 ms275 MS 27-275 SNDX-275 SNDX275 MS27275 37.997177716390
10009365 MTT Cell Proliferation Assay Kit - 2007-02-15 114.533050951503 mtt-cell-proliferation-assay-kit assays kits screen measures measurements cells cellular growth factors signaling signalling molecules transcription DNA pathological cancers aging cycles progression regulatory cytokines mitogens drugs inductions inhibitors inhibits inhibitions in vitro plasma membranes formazan intracellular NAD(P)H-oxidoreductases NADPH-oxidoreductases proteins enzymes enzymatic cleavage microtiter plates tertrazolium salts mitochondrial dehydrogenases cancer cell-based assay cell based assay cba 114.533050951503
600330 Multi-Parameter Apoptosis Assay Kit - 2010-08-18 89.454780052167 multi-parameter-apoptosis-assay-kit assays kits measures measurements apoptosis cells death cycles tissues homeostasis dysregulation neurodegenerative diseases ischemic damages autoimmune disorders cancers drugs discovery signaling pathways membranes phospholipids phosphatidylserines phosphatidylethanolamines leaflets bilayers externalizations residues plasma phospholipids binding proteins fluorochrome-labeled fluorochromes annexin V fluorescence microscopy flow cytometry FC plate readers TUNEL TdT-mediated dUTP Nick-End Labeling analysis ISEL in situ end labeling DNA deoxyribonucleic acids mitochondrial transmembranes tetramethylrhodamines ethyls esters TMRE lipophilics probes laddering detection fragmentation FITC-conjugated fluoresceins 89.454780052167
13779 MutL Protein Homolog 1 Monoclonal Antibody (Clone 164C819) - 2010-04-29 5.599889502762 mutl-protein-homolog-1-monoclonal-antibody-clone-164c819 HNPCC; MLH1 antibodies western blots bloting immunobloting WB Mut-L Mut L MLH 1 MLH-1 DNA genes cancers colons 5.599889502762
10012600 Myricetin 529-44-2 >98% 2009-02-20 24.470613873541 myricetin NSC 407290; Cannabiscetin flavonoid antioxidant oxLDL CD36 atherosclerosis cancers JAK1 STAT3 MEK1 24.470613873541
10008581 Myristoleic Acid methyl ester 56219-06-8 >98% 2007-04-17 0.314917127071 myristoleic-acid-methyl-ester cytotoxic Serenoa S. repens apoptosis necrosis prostate cancers cheese whey fatty acids Candida C. albicans MIC minimal inhibitory concentration in vivo esters hydrophobic 0.314917127071
600480 NAD+/NADH Cell-Based Assay Kit New - 2012-02-29 105.680926438828 nad-nadh-cell-based-assay-kit Nicotinamide adenine dinucleotide/Nicotinamide adenine dinucleotide, reduced cells assay kits CBAs colorimetric measuring measurement Nicotinamide adenine dinucleotide/Nicotinamide adenine dinucleotide reduced cells oxidized cofactors redox oxidations reductions reactions electrons transporters cellular substrates enzymes acetyl groups proteins posttranslational respiratory functions citric acids cycles tricarboxylic TCA Kreb's ATP adenosine 5'-triphosphate oxidative phosphorylation metabolic activity biosynthesis de novo phosphoribosyltransferase NAMPT organs aging cytosolic mammalian death apoptosis signaling transcriptional metabolic disorders intracellular cultured alcohol dehydrogenases acetoaldehydes NAD kit NADP NADH NAD+ NAD-+ + 105.680926438828
579040 Nampt/Visfatin (mouse/rat) EIA Kit - 2011-08-08 24.981108782625 nampt-visfatin-mouse-rat-eia-kit Nicotinamide Phophoribosyltransferase/Visfatin Pre-B-Cell Colony-Enhancing Factor/Visfatin immunometric kits measures measurements EIA enzymes immunoassays nicotinamides phosphoribosyltransferases coenzymes salvage pathways adenine dinucleoties NAD+ cellular metabolisms pre-B-cell cells colony enhancing factors PBEF visceral fats plasmas obesity insulin receptors proteins intracellular extracellular mesangial kidneys glucose uptake diabetic nephropathy exercise skeletal muscles NAD+-dependant sirtuin-dependant circadian oscillations cancers apoptosis serums body mass index mass inflammation livers cirrhosis beta .beta. β leukocytes tissues mouse 24.981108782625
13055 Naphthofluorescein 61419-02-1 ≥98% 2009-03-20 1.601988950276 naphthofluorescein CCG 8295 furin matrix metalloproteinase MTA-MMP MMP2 motility invasion cancer metastasis MMP inhibitors naphthafluorescein 1.601988950276
10387 Naringenin-4'-O-β-D-Glucuronide 158196-35-1 ≥88% 2010-04-23 0E-12 naringenin-4-o-d-glucuronide flavanone inhibits inhibition inhibitor CYP1A2 CYP 1A2 cytochrome P450 158196-35-1 0E-12
10388 Naringenin-7-O-β-D-Glucuronide - ≥98% 2010-04-24 0E-12 naringenin-7-o-d-glucuronide 158196-34-0 inhibits inhibition cytochrome P450 inhibitor CYP1A2 0E-12
11633 NCOR2/SMRT (human recombinant) New - ≥60% 2012-04-09 85.995493155963 ncor2-smrt-human-recombinant TRAC; T3 Receptor-Associating Factor; Nuclear Receptor Corepressor 2; Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor; CTG Repeat Protein 26; SMRT; SMAP270; Thyroid-Retinoic-Acid-Receptor-Associated Corepressor epigenetics histones deacetylases transcriptional regulations corepressor co-repressor complexes metabolism HDACs HDAC3 class I HDAC yeast Rpd DAD E2F TFIIE TFIIF NF-κB p300 Stat3 p53 retinoblastoma protein Rb protein differentiation cell death angiogenesis inflammation cancers inflammatory diseases 85.995493155963
10584 (−)-Neplanocin A Exclusive 72877-50-0 ≥98% ✓ 2011-03-25 62.464135753748 -neplanocin-a S-adenosylhomocysteines hydrolases SAH inhibitors S-adenosylmethionines SAM methyltransferases antitumor antiviral cancer virus methylation Neplanocin A neplanocinA anti-tumor 62.464135753748
13755 NF-κB (p50) Monoclonal Antibody (Clone 2J10D7) - 2010-02-05 12.341988950276 nf-b-p50-monoclonal-antibody-clone-2j10d7 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB nuclear transcription factors cytokines UV radiations stress injury bacterial viral cells growth differentiation proliferation apoptosis inflammation DNA AIDS cancers arthritis western blots blotting immunoblotting IHC WB immunohistochemistry 12.341988950276
13754 NF-κB (p50) Polyclonal Antibody - 2010-04-27 11.631353591160 nf-b-p50-polyclonal-antibody NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB nuclear transcription factors DNA p65 N-terminal binding western blots blotting immunoblotting WB antibodies 11.631353591160
13756 NF-κB (p65) Monoclonal Antibody-biotin (Clone 112A1021) - 2010-02-11 20.124822415153 nf-b-p65-monoclonal-antibody-biotin-clone-112a1021 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting WB biotins biotinylated biontinylation 112A1021 clones 20.124822415153
13752 NF-κB (p65) Monoclonal Antibody (Clone 112A1021) - 2010-02-11 20.313535911601 nf-b-p65-monoclonal-antibody-clone-112a1021 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting flow cytometry FC WB immunohistochemistry IHC 20.313535911601
13751 NF-κB (p65) NLS Polyclonal Antibody - 2010-02-11 20.545580110496 nf-b-p65-nls-polyclonal-antibody Nuclear Factor-κB (p65) Nuclear Localization Signal NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB transcription factors N-terminal C-terminal terminals terminus signals tissues nuclear receptors western blots blotting immunoblotting WB immunocytochemistry ICC antibodies 20.545580110496
13757 NF-κB (p65) Polyclonal Antibody (aa 2-17) - 2010-02-11 14.566101026045 nf-b-p65-polyclonal-antibody-aa-2-17 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting WB amino acids 2 7 14.566101026045
13753 NF-κB (p65) Polyclonal Antibody (aa 538-546) - 2010-02-11 19.484806629834 nf-b-p65-polyclonal-antibody-aa-538-546 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting WB amino acids 538 546 19.484806629834
10011250 NH125 278603-08-0 ≥95% 2008-11-21 7.912790055249 nh125 antibacterial histidine kinase cancer cell cycle eEF-2K drug resistance imidazoles 7.912790055249
10649 Niclosamide 50-65-7 ≥95% 2011-01-12 3.086436464088 niclosamide antihelminthic helminth tapeworms inhibitors STAT3 cancers proliferation anti-helminthic salicylanilide Du 145 DU145 DU-145 Niclosamide, 2-Aminoethanol (1:1) Aventis Brand of Niclosamide Bayer Brand of Niclosamide Clonitralide Niclosamide Bayluscide Bayer 2353 Trédémine Niclocide Radewerm Phenasal Bayer 73 Yomesan Fenasal 3.086436464088
10010422 Nilotinib 641571-10-0 ≥98% 2009-10-23 24.972909760589 nilotinib AMN107 tyrosine kinases inhibitors therapy cancer Bcr/Abl chronic myeloid leukemia MLL philadelphia chromosomes acute lymphoblastic ALL imatinib gleevec genes expression DNA helicase complex cyclins cyclin-dependent cells proliferation 24.972909760589
10006966 Nitrotyrosine Monoclonal Antibody - Biotinylated - 2005-04-15 9.714060773480 nitrotyrosine-monoclonal-antibody-biotinylated antibodies western blots blotting WB antisera antiserum peroxynitrite western blots blotting nitric oxide nitration proteins NO superoxide alzheimer's diseases oxidative injury stress IHC immunohistochemistry IP immunoprecipitation EIA enzyme immunoassay species independent detection immunoblotting Enzyme-linked immunosorbent assays 9.714060773480
10005705 NO-Indomethacin Exclusive 301838-28-8 >98% ✓ 2004-10-20 5.517237569061 no-indomethacin NCX 2121 inhibition inhibitors NSAIDs non-steroidal anti-inflammatory drugs inhibits nitric oxides cancer chemopreventative donor gastrointestinal NOs PaCa-2 PaCa2 pancreatic analgesic 5.517237569061
10011255 NSC 210902 51726-83-1 ≥95% 2008-09-15 3.973812154697 nsc-210902 Inhibitor inhibits inhibition CK2 kinase cell signaling apoptosis cancers NSC210902 3.973812154697
13196 NSC 23766 (hydrochloride) 1177865-17-6 ≥98% 2010-07-20 18.908674033149 nsc-23766-hydrochloride 733767-34-5 GTPases cells cycles growth proliferations cell-cell adhesions motility differentiation guanine nucleotides exchange factors GEFs inhibitors inhibits inhibition cell migration Aminoquinolines angiogenesis leukemia cancers gene expression Rac1 Inhibitor 18.908674033149
13303 NSC 663284 383907-43-5 ≥98% 2010-04-01 14.270745856353 nsc-663284 Cdc25 Phosphatase Inhibitor II; DA-3003-1 dual specificity phosphatases CDC25 Cdc25A Cdc25B Cdc25C proto-oncogenes cancers inhibitors VHR PTP1B MKP-1 Cdk1 Cdk2 cells proliferation tumors inhibits inhibition Cdcs potent cell-permeable irreversible 14.270745856353
10758 NSD2 (human recombinant) New - ≥90% 2012-02-01 5.306521739130 nsd2-human-recombinant Histone-lysine N-methyltransferase NSD2 isoform 1; MMSET; TRX5; Wolf-Hirschorn Syndrome Candidate 1; Nuclear Receptor SET domain-containing protein 2; Multiple myeloma SET domain-containing protein; Protein trithorax-5; WHSC1; KIAA1090 NSD2 SET-Domains Lysine methyltransferases chromatin WHSC1 MMSET WHSCH1-like multiple myeloma translocations histones H3 H4 H3K36 H4K44 H4K20 53BP1 dimethylation DNA damages NSDs NSD-2 active 5.306521739130
13308 NU 7026 154447-35-5 ≥95% 2009-09-21 33.540027624309 nu-7026 DNA-PK Inhibitor II; LY293646 DNA-dependent proteins kinase DNA-PK strand breaks ionizing radiation DNA repair inhibitors inhibitis inhibitions PI3K ATM ATR PAPR-1 PARP1 cytotoxicity topoisomerase II leukemia mitoxantrone NU-7026 NU 7026 ataxia telangiectasia mutated Rad3 related Rad3-related Rad 3 Rad-3 DNA-Dependent Protein Kinase 33.540027624309
18585 (−)-Nutlin-3 - ≥98% 2008-08-06 347.018968692449 -nutlin-3 Nutlin 3a P53 cellular stress proliferation cells cycle apoptosis tumor suppressor MDM2 agents Nutlin-3 enantiomer a 347.018968692449
10009816 (+)-Nutlin-3 - ≥98% 2008-08-11 130.763991712707 -nutlin-3 Nutlin 3b p53 cellular stress proliferation cells cycle apoptosis tumer suppressor MDM2 inactive inhibitors inhibits inhibition Nutlin-3 enantiomer b 130.763991712707
10004372 (±)-Nutlin-3 548472-68-0 >98% 2004-04-06 82.674496387590 -nutlin-3 apoptosis cancers p53 inhibits inhibitors induces apoptotic re-activation reactivation antioncogenic tumors xenografts license:hoffmanlaroche Nutlin3 nutlins 82.674496387590
13641 NVP-AEW541 (hydrochloride) - ≥98% 2010-07-28 41.979834254143 nvp-aew541-hydrochloride 475488-34-7 IGF-1R Insulin-like growth factor I receptors tyrosine kinases angiogenesis cells proliferation cancers inhibitors inhibition inhibits 701294-63-5 Ins-R NWT-21 Pyrroles 41.979834254143
10565 NVP-BEZ235 915019-65-7 ≥98% 2010-10-12 48.377927007512 nvp-bez235 phosphatidylinositols 3-kinases PI3Ks Akt/PKB mTORs cancers inhibitors inhibits inhibition angiogenesis genes expressions apoptosis differentiation rapamycin phosphatidyls inositols phosphatidylinositols-3-kinase Imidazoles BEZ235 48.377927007512
11176 O6-methylguanine-DNA Methyltransferase (human recombinant) New - ≥80% 2011-12-06 0.508720930233 o6-methylguanine-dna-methyltransferase-human-recombinant MGMT DNA repair cancers 06-demethylases suicide enzymes guanine thymine cytosine replication mutations cysteine oligo nucleotides PvuII dsDNA full-length full length demethylating thymine active 0.508720930233
10010547 O-Arachidonoyl Glycidol Exclusive 439146-24-4 >98% ✓ 2008-03-31 19.853933701658 o-arachidonoyl-glycidol 2-AG 2-arachidonoyl glycerol 2-oleoylglycerol N-arachidonoylethanolamine anandamide AEA FAAH endocannabinoid obesity pain neurodegenerative diseases monoacylglycerol lipase inhibits inhibitors inhibitions MAGL MGL cannabinoids 19.853933701658
11726 Oleanolic Acid New 508-02-1 ≥95% 2012-05-16 103.859163597298 oleanolic-acid NSC 114945; Oleanoic Acid; Caryophyllin; Gledigenin 1; Giganteumgenin C; Astrantiagenin C; Virgaureagenin B herbals medicines inflammation cancers viruses hyperlipidemia squalene antiinflammatory anti-inflammatory anti-hyperlipidemic antihyperlipidemic hepatoprotective in vivo antiviral anti-viral anti-tumors antitumor triterpenoids Michael addition Keap1 IKK JAK1 STAT3 PTEM proteins actin cytoskeleton oleonolic acid 103.859163597298
10010299 Oleoyl 3-carbacyclic Phosphatidic Acid Exclusive - ≥95% ✓ 2009-10-14 15.632520718232 oleoyl-3-carbacyclic-phosphatidic-acid 3-ccPA 18:1 cyclic phosphatidic acids cPAs lysophosphatidic LPA ccPA 3ccPA oleate transcellular migration MM1 cells mesothelial autotoxin cancer survival growth migration invasion metastasis antagonist LPA1 LPA2 LPA3 476310-24-4 15.632520718232
11342 Oligomycin A New 579-13-5 ≥98% 2012-03-05 15.926646341463 oligomycin-a MCH 32 11030-76-5 21307-25-5 31422-20-5 macrolide isomers mitochondria F1F0-ATP synthases apoptosis antifungals antitumors nematocidal Streptomyces toxic metabolism analogs MCH-32 MCH32 15.926646341463
10010240 Olomoucine 101622-51-9 ≥98% 2007-09-13 11.101562746645 olomoucine inhibitors inhibits inhibition cyclin-dependent kinases cdks spinal cord injury SCI G1 cell cycle 11.101562746645
14070 ONO-8711 216158-34-8 ≥98% 2011-06-15 21.559254143646 ono-8711 ONO 8711 ONO8711 prostaglandins EPs EP1 receptors potent PGs antagonists AH-6809 AH 6809 AH6809 14060 14050 SC-19220 SC19220 SC 19220 21.559254143646
13176 Oxamflatin 151720-43-3 ≥95% 2010-11-16 28.367523020257 oxamflatin Metacept 3 HDACs histones deacetylases genes expressions morphology motility apoptosis cells cycles cancers reducing reduction proliferation Acids Hydroxamic Hydroxamic Acids Acid Hydroxamic Hydroxamic Acid 28.367523020257
600008 p53 Cell-Based Activation/Translocation Assay Kit - 2009-03-10 4.725874769798 p53-cell-based-activation-translocation-assay-kit p53 dsDNA double-stranded tumors suppressors proteins guardians of the genomes cells cellular responses genotoxic stresses activity cycles arrests apoptosis senescence humans cancers mutations inactivated binding ubiquitination acetylation phosphorylation sumoylation neddylation methylation glycosylation damages oncogenes ribosomal cell-matrix matrices adhesion hypoxia p21 WAF1 Cip1 MDM2 GADD45 Cyclin G Bax IGF-BP3 bcl-2 Bcl-XL cyclins B1 MAP4 survivin HPV16 PARP-1 WT1 E1b/E4 degradation nucleus cytoplasms proteasomes promoter carcinogenesis endogenous wild-type heterogenous autosomal dominant disorders Li Fraumeni Syndromes nuclear extracts assays cell-based assay cell based assay cba 4.725874769798
600030 p53 Designer Transcription Factor Assay Kit - 2009-01-08 17.855584072035 p53-designer-transcription-factor-assay-kit dsDNA double-stranded tumors suppressors proteins guardians of the genomes cells cellular responses genotoxic stresses activity cycles arrests apoptosis senescence humans cancers mutations inactivated binding ubiquitination acetylation phosphorylation sumoylation neddylation methylation glycosylation damages oncogenes ribosomal cell-matrix matrices adhesion hypoxia p21 WAF1 Cip1 MDM2 GADD45 Cyclin G Bax IGF-BP3 bcl-2 Bcl-XL cyclins B1 MAP4 survivin HPV16 PARP-1 WT1 E1b/E4 degradation nucleus cytoplasms proteasomes promoter carcinogenesis endogenous wild-type heterogenous autosomal dominant disorders Li Fraumeni Syndromes nuclear extracts ELISAs assays enzyme-linked immunosorbent TFs T.F. factors assays 17.855584072035
10004806 p53 Monoclonal Antibody (Clone BP53-12) - 2004-06-17 3.627384898710 p53-monoclonal-antibody-clone-bp53-12 proteins WB western blots blotting antibodies antisera antiserum DNA anti-oncogenic apoptosis cancers p53 apoptotic antioncogenic flow cytometry immunocytochemistry ICC IHC immunohistochemistry transcription factors cellular stress damage hypoxia shock guardian of the genome special:month specialdiscount:15 specialstart:2008-01-01 specialend:2008-01-31 immunoblotting FC 3.627384898710
10004807 p53 (Phospho-Ser392) Polyclonal Antibody - Affinity-purified 2004-05-18 7.687684580612 p53-phospho-ser392-polyclonal-antibody phosphorylateds proteins WB western blots blotting antibodies antisera antiserum DNA binding anti-oncogenic apoptosis cancer p53 re-activator reactivator induces apoptotic re-activation reactivation antioncogenic phospho-specific immunoblotting 7.687684580612
10005291 p53 Product Pack - 2004-09-08 10.753913443830 p53-product-pack DNA binding anti-oncogenic apoptosis cancer p53 re-activators reactivators induces apoptotic re-activation reactivation antioncogenic packs 10.753913443830
600060 p53 Total and p53 (Phospho-Ser392) Dual Staining Assay Kit - 2009-03-10 3.415837937385 p53-total-and-p53-phospho-ser392-dual-staining-assay-kit kits assays measuring measurements tumors treatments DyLightTM (-)-Nutlin-3 positive ontrols p53(Phospho-Ser392) dsDNA double-stranded suppressors proteins guardians of the genomes cells cellular responses genotoxic stresses activity cycles arrests apoptosis senescence cancers mutations inactivated binding ubiquitination acetylation phosphorylation sumoylation neddylation methylation glycosylation damages oncogenes ribosomal cell-matrix matrices adhesion hypoxia p21 WAF1 Cip1 MDM2 GADD45 Cyclin G Bax IGF-BP3 bcl-2 Bcl-XL cyclins B1 MAP4 survivin HPV16 PARP-1 WT1 E1b/E4 degradation nucleus cytoplasms proteasomes promoter carcinogenesis endogenous autosomal Li Fraumeni Syndromes nuclear extracts cell-based assays cell based assay cba 3.415837937385
600020 p53 Transcription Factor Assay Kit - 2008-10-27 25.678618784530 p53-transcription-factor-assay-kit dsDNA double-stranded tumors suppressors proteins guardians of the genomes cells cellular responses genotoxic stresses activity cycles arrests apoptosis senescence humans cancers mutations inactivated binding ubiquitination acetylation phosphorylation sumoylation neddylation methylation glycosylation damages oncogenes ribosomal cell-matrix matrices adhesion hypoxia p21 WAF1 Cip1 MDM2 GADD45 Cyclin G Bax IGF-BP3 bcl-2 bcl-X cyclins B1 MAP4 survivin HPV16 PARP-1 WT1 E1b/E4 degradation nucleus cytoplasms proteasomes promoter carcinogenesis endogenous wild-type heterogenous autosomal dominant disorders Li Fraumeni Syndromes nuclear extracts ELISAs assays enzyme-linked immunosorbent TFs T.F. factors assays 25.678618784530
10009317 PAC-1 315183-21-2 ≥98% 2007-07-12 10.466740331491 pac-1 Procaspase-activating Compound 1 in vitro procaspase-3 apoptosis cancers cells death drugs treatment acivators procaspases PAC1 10.466740331491
10461 Paclitaxel 33069-62-4 ≥98% 2010-08-23 44.641625537140 paclitaxel Taxol®; NSC 125973 Microtubules cancers cervical HeLa lung A549 breast MCF-7 colon HT-29 ovarian OVG-1 pancreatic PC-Sh carcinomas chemotherapy mitotic arrest apoptosis JNK BCL-2 p53 Pacific yew tree c-Jun cyclin-dependent kinases multipolar spindle formation Capxol Mitotax Onxal QW 8184 Yewtaxan Tocosol Taxus Liberte Genexol-PM Genetaxyl EndoTAG 1 Ebetaxwl DHP 107 ABI 007 Bristol-Myers Squibb Brand of Paclitaxel Bristol-Myers Brand of Paclitaxel Paclitaxel (4 alpha)-Isomer Lemery Brand of Paclitaxel Ivax Brand of Paclitaxel Bull Brand of Paclitaxel 7-epi-Taxol 7 epi Taxol Paclitaxel NSC-125973 NSC 125973 Bris Taxol NSC125973 Taxol A Anzatax Praxel Paxene Taxol Onxol 44.641625537140
10500 PAD4 (human recombinant) - ≥95% 2010-05-27 68.342983425414 pad4-human-recombinant Peptidylarginine Deiminase 4; Protein Arginine Deiminase 4 guanidino modifying enzymes citrillination histones deiminase MS multiple sclerosis Alzheimer's diseases glaucoma IOP intraocular pressure cancers peptidylarginine deiminase active 68.342983425414
700560 PAD4 Inhibitor Screening Assay Kit - 2011-05-04 49.092011970534 pad4-inhibitor-screening-assay-kit Protein Arginine Deiminase 4; Peptidylarginine Deiminase 4 kits assays measures measurements proteins arginines deiminases PADs guanidine-modifying enzymes peptidylarginine deiminase amidinotransferases nucleus homodimers transcriptional coregulator catalyzes residues citrulline calcium-dependent substrates histones H2A H3 H4 post-translational modifications genes regulations autocitrullination inhibits enzymatic activity cells rheumatoid arthritis citrulline-containing immune response autoantibodies tissues multiple sclerosis Alzheimer's diseases glaucoma cancers human deiminates N-α-benzoyl-L-arginine ethyl esters BAEE kinetic ammonia detectors fluorescent fluorescence 49.092011970534
10007358 Palmitic Acid methyl ester 112-39-0 >99% 2006-02-17 17.079586883568 palmitic-acid-methyl-ester MP; Methyl Palmitate esters saturated fatty acids synthesized synthesis plants animals acetyl coenzymes CoA energy storage 16-carbon dietary fats plasma lipoproteins expression COX-2 cyclooxygenase-2 cyclooxygenases proteins acylation lipids anchoring signaling signalling molecules 17.079586883568
10010298 Palmitoleoyl 3-carbacyclic Phosphatidic Acid Exclusive 910228-13-6 ≥95% ✓ 2009-11-03 11.081066723331 palmitoleoyl-3-carbacyclic-phosphatidic-acid 3-carbacyclic PA; 3-ccPA 16:1 cyclic phosphatidic acids cPAs lysophosphatidic LPA ccPA 3ccPA palmitoleate transcellular migration MM1 cells mesothelial autotoxins cancer survival growth migration invasion metastasis NPP2 ENPP2 ectonucleotide pyro phosphatase/phosphodiesterase 2 11.081066723331
10010293 Palmitoyl 3-carbacyclic Phosphatidic Acid Exclusive 476310-22-2 ≥95% ✓ 2009-10-07 15.241019588146 palmitoyl-3-carbacyclic-phosphatidic-acid 3-ccPA 16:0 cyclic acids cPAs lysophosphatidic LPA ccPA 3ccPA palmitate transcellular migration MM1 cells mesothelial autotoxins cancers survival growth migration invasion metastasis 15.241019588146
13557 PARP (Cleaved) Monoclonal Antibody - 2009-08-11 7.237209944751 parp-cleaved-monoclonal-antibody poly ADP ribose polymerase ADP-ribose DNA western blots immunoblotting WB flow cytometry intracellular antibodies FC blotting 7.237209944751
70080 Parthenolide New 20554-84-1 ≥98% 2012-05-18 92.222222222222 parthenolide 119325-19-8 120852-67-7 344906-67-8 leishmania apoptosis cancers genes regulations inflammation NF-kB lactones plats feverfew Tanacetum parthenium T. promastigote Leishmania amazonensis L. STAT mediated anti-apoptotic transcriptions inhibits inhibiting inhibition NOD2 92.222222222222
10994 Paxillin (Phospho-Tyr118) Polyclonal Antibody New - 2012-01-13 0E-12 paxillin-phospho-tyr118-polyclonal-antibody proteins LIM domains ERK-regulated scaffolds vinculin-binding phosphorylation Western blots blotting WB ERKs binds binding vinculin JNK 0E-12
10009115 pCAF Histone Acetyltransferase - ≥95% 2006-10-18 20.201293020038 pcaf-histone-acetyltransferase HAT; p300/(CREB binding protein) Associated Factor proteins binding GCN5 nuclear acetyltransferases C-terminal C-terminus acetyl-lysine N-terminal N-terminus histones H3 H4 transcriptional activators MyoD E2F1 p53 acetylates PTEN K125 K128 catalytic cleft in vivo enzymes cancers active 20.201293020038
10004805 PCNA Monoclonal Antibody (Clone IPO-38) - 2004-08-27 3.658872928177 pcna-monoclonal-antibody-clone-ipo-38 Nuclear Antigen of Proliferating Cells; Proliferating Cell Nuclear Antigen WB western blots blotting IHC immunohistochemistry immunoblots proliferating cells nuclear antigens ipo38 flow cytometry immunocytochemistry ICC mitosis DNA polymerases holoenzymes antibodies antisera antiserum cancers immunoblotting FC 3.658872928177
10007185 PCSK9 (human) Polyclonal Antibody - 2005-11-30 24.572722967640 pcsk9-human-polyclonal-antibody NARC-1; Proprotein Convertase Subtilisin Kexin 9 atherosclerosis proteins diseases antibodies antisera antiserum WB western blots blotting ICC immunocytochemistry serines proteases family lipoproteins subtilisin metabolisms mutations genes autosomal doimant dominance hypercholesterolemia low density LDLs overexpressions plasmas total cholesterols livers kidneys lungs spleens jejunums ileums colons muscles golgi tissues atherosclerosis immunoblotting 24.572722967640
10009581 PCSK9 (mouse) Blocking Peptide - 2007-01-22 9.896837016574 pcsk9-mouse-blocking-peptide Proprotein Convertase Subtilisin Kexin 9; NARC-1 neural apoptosis regulated convertase 1 proteins antibodies antisera antiserum WB western blots blotting ICC immunocytochemistry serines proteases lipoproteins subtilisin metabolisms mutations genes autosomal doimant dominance hypercholesterolemia low density LDLs overexpressions plasmas total cholesterols cancer cells 9.896837016574
10008811 PCSK9 (mouse) Polyclonal Antibody - 2007-01-22 10.554704856063 pcsk9-mouse-polyclonal-antibody Proprotein Convertase Subtilisin Kexin 9; NARC-1 immunoblot neural apoptosis regulated convertase 1 atherosclerosis proteins antibodies antisera antiserum WB western blots blotting ICC immunocytochemistry serines proteases lipoproteins subtilisin metabolisms mutations genes autosomal doimant dominance hypercholesterolemia low density LDLs overexpressions plasmas total cholesterols atherosclerosis PCSK-9 immunoblotting 10.554704856063
13034 PD 0325901 391210-10-9 ≥98% 2009-03-13 45.531495720653 pd-0325901 MEK ERK RAS RAF MAPK tumors stem cells cancers differentiation signaling GSK3 kinase inhibitors inhibits inhibition pd325901 pd 325901 PD0325901 45.531495720653
9000988 PD 166326 New 185039-91-2 ≥98% 2011-11-30 13.817691869969 pd-166326 inhibitors cancers c-abl c-src Bcl/Abl tyrosine receptors kinases cells signaling leukemia CML chronic myelogenous leukemia PD-166326 PD166326 pyridopyrimidine STI571 mesylate 13.817691869969
13032 PD 173074 219580-11-7 ≥98% 2009-07-29 48.426305915947 pd-173074 fibroblast growths factors receptors FGFRs FGFR1 tyrosine kinase activity activities activation signals propagation inhibitors inhibition inhibits autophosphorylation PDGFR c-Src cSrc c Src EGFR InsR MEK PKC FGFR2 FGFR3 FGFR4 FGFR5 angiogenesis cancers tumors self-renewal self renewal stems cells ERK1/2 ERK-1/2 ERK 1/2 48.426305915947
10012431 PD 184161 Exclusive 212631-67-9 ≥98% ✓ 2009-06-09 12.113645758542 pd-184161 MEK inhibitors MAP kinase ERK signaling cancer MEK 1/2 inhibition inhibited ERK 1/2 potent selective pd184161 12.113645758542
10006726 PD 98059 167869-21-8 >98% 2005-09-12 17.671676392078 pd-98059 potent selective MAPK mitogen-activated proteins kinases family serines threonines cellular PD-98059 programs cells proliferation differentiation movement death noncompetitive inhibits inhibitors inhibition pathways activation MAPKK1 Raf MEK MAPKK2 MAPKK-1 PD98059 MAPKK-2 ERK 17.671676392078
10006341 PDM 11 Exclusive - >98% ✓ 2005-03-23 16.833740122268 pdm-11 resveratrol analogs analogues aryl hydrocarbons receptors anatagonists AhRs ligand-dependents ligands xenobiotics PDM11 PDM-11 estrogen dioxin poisonings stilbene xenobiotics polyaromatics soot coal tar 16.833740122268
10006342 PDM 2 Exclusive 688348-25-6 >98% ✓ 2005-03-29 16.888988741053 pdm-2 AhRs antagonists stilbenes dioxins aryl hydrocarbons receptors ligand-dependent transcription factors resveratrol analogs ligands xenobiotics PDM2 PDM-2 estrogen poisonings xenobiotics polyaromatics soot coal tar cancers 16.888988741053
62595 PDMP (hydrochloride) 73257-80-4 >98% 2004-08-10 0.810712116474 pdmp-hydrochloride analogs analogues inhibits inhibitors inhibition cytotoxicity glucosylceramides aynthases chirality stereoisomers sphingosine (±)PDMP 0.810712116474
11440 Penicillic Acid New 90-65-3 ≥98% 2012-04-18 124.444444444445 penicillic-acid NSC 402844 NSC402844 NSC-402844 quorum sensing virulence mycotoxins inhibitors inhibits inhibition bacterial infection Fas apoptosis caspase-8 Burkitt’s lymphoma Penicillium mold corn grains acids Pseudomonas aeruginosa raji genes 124.444444444445
10005983 Pentafluorobenzenesulfonyl fluorescein 728912-45-6 >98% 2005-02-22 17.208715469613 pentafluorobenzenesulfonyl-fluorescein fluoresceins hydrogen peroxides oxidative stress fluorescents probes ROS reactive oxygen species perhydrolysis H2O2 17.208715469613
500290 Phagocytosis Assay Kit (IgG FITC) - 2009-04-09 143.746594904470 phagocytosis-assay-kit-igg-fitc kits assays measuring measurement ingestion killing phagocytic leukocytes defense pathogens microbe-innate immune cytoskeletal rearrangement membrane trafficking microbial mechanisms pro-inflammatory anti-inflammatory cytokines chemokines apoptosis antigen immune systems pathological Multiple Sclerosis Alzheimer's diseases atherosclerosis bacterial fungal infections in vitro fluorescently opsonizing latex beads fluorescently-labeled flow cytometry cytometric analysis quantification cell-based cell based cba 143.746594904470
600540 Phagocytosis Assay Kit (IgG PE) New - 2012-01-10 108.089974089607 phagocytosis-assay-kit-igg-pe kits assays measuring measurement ingestion killing phagocytic leukocytes defense pathogens microbe-innate immune cytoskeletal rearrangement membrane trafficking microbial mechanisms pro-inflammatory anti-inflammatory cytokines chemokines apoptosis antigen immune systems pathological Multiple Sclerosis Alzheimer's diseases atherosclerosis bacterial fungal infections in vitro fluorescently opsonizing latex beads fluorescently-labeled flow cytometry cytometric analysis quantification cell-based cell based cba phycoerythrins probes fluorescence 108.089974089607
10007191 PH Domain Leucine-rich Repeat Protein Phosphatase 1 Polyclonal Antibody - 2006-01-04 5.081698895027 ph-domain-leucine-rich-repeat-protein-phosphatase-1-polyclonal-antibody Suprachiasmatic Nucleus Circadian Oscillatory Protein; SCOP; PLEKHE1 Protein; PHLPP1; KIAA0606 Protein proteins diseases antibodies antisera antiserum western blots blotting immunocytochemistry ICC immunohistochemistry IHC cancers WB immunoblotting PH Domain Leucine-rich Repeat Protein Phosphatase Polyclonal Antibody 5.081698895027
10007192 PH Domain Leucine-rich Repeat Protein Phosphatase Blocking Peptide - 2006-01-30 4.502071823204 ph-domain-leucine-rich-repeat-protein-phosphatase-blocking-peptide Suprachiasmatic Nucleus Circadian Oscillatory Protein; SCOP; PLEKHE1 Protein; PHLPP; KIAA0606 Protein western blotting blots signaling signalling WB IHC ICC immunohistochemistry formalin-fixed paraffin-embedded immunocytochemistry proteins kinases Akt cells growth death serine residues Ser473 C-terminal hydrophobic motifs human cancers dephosphorylates dephosphorylation reduces activity apoptosis apoptotic colon glioblastomas lines tumors brain 4.502071823204
10735 Phthalazinone pyrazole Exclusive 880487-62-7 ≥98% ✓ 2011-07-27 5.267071823204 phthalazinone-pyrazole inhibitors inhibits inhibition auroras kinases cells cycle cancers centrosomes mitosis spindles cancers proliferation cells growth phosphorylation Auroroa-A Aurora-B Aurora-C A B C HCT116 HCT-116 Colo 116 HCT 116 Colo116 Colo-116 MCF7 MCF-7 MCF 7 5.267071823204
10009209 PI-103 371935-74-9 ≥98% 2007-01-19 22.568281495123 pi-103 phosphoinositides PI3-kinases Phosphatidylinositols cancers Glioma DNA-PK mTOR inhibitors inhibits inhibition anti-proliferatives proliferation PI103 22.568281495123
10010177 PI3-Kinase α Inhibitor 2 Exclusive 371943-05-4 ≥98% ✓ 2007-08-02 25.476615510538 pi3-kinase-inhibitor-2 PI3Kα Inhibitor 2; Phosphatidylinositol 3-Kinase α Inhibitor 2 phosphoinositides 3-kinases PI3-kinase phosphatidylinositols cancers proliferations inhibits inhibitors inhibition PI3-K PI3K inhibitory A375 melanoma cell proliferation 25.476615510538
13326 Pifithrin-α 63208-82-2 ≥95% 2009-07-16 26.307106353591 pifithrin p53 apoptosis DNA damage cyclin D1 C8 cells HUVECs endothelial cells dependent independent inactivator 26.307106353591
10748 Pifithrin-μ 64984-31-2 ≥98% 2011-06-20 16.692451657459 pifithrin PFT-μ; 2-Phenylethynesulfonamide p53 apoptosis Bcl-xL Bcl-2 mitochondria inhibitors nutlin heat shock proteins 70 HSP70 PES PAS pifithrin-mu pifithrin mu PFTμ PFTu 2-phenylacetylenylsulfonamide 2-phenylacetylenesulfonamide BclxL Bc12 16.692451657459
10009210 PIK-75 372196-67-3 ≥98% 2010-03-10 13.776209126253 pik-75 p110α PI3K insulin signaling signals cancers inhibitors inhibits inhibition signalling p110a phosphatidylinositol 3-kinase phosphorylation Akt activation mTORC1 PIP2 PIP3 p110β p110α p110γ p110beta p110 alpha p110.beta. p110.alpha. p110gamma p110.gamma.p110g Mixtures, Sulfonamide Sulfonamide Mixtures Sulfonamides 13.776209126253
89130 Pimonidazole 70132-50-2 >98% 2008-04-23 7.211491712707 pimonidazole NSC 380540; Ro 03-8799 hypoxia hypoxic cells radiosensitizer tumors marker hypoxia hypoxyprobe 7.211491712707
10006284 PINK1 Blocking Peptide - 2005-01-18 5.714456721915 pink1-blocking-peptide PTEN Induced Putative Kinase 1; PARK6; BRPK antibodies western blotting blots signaling signalling IHC WB formalin immunohistochemistry controls peptides phosphatases tensin homolog dephosphorylates lipids human cancers tumor-suppressive pathway mRNA mitochondria C-terminus Parkinson's diseases phosphatidylinositols phosphates 5.714456721915
10006283 PINK1 Polyclonal Antibody - 2004-12-28 33.141270718232 pink1-polyclonal-antibody PARK6; BRPK; PTEN Induced Putative Kinase 1 proteins antibodies antisera antiserum wb western blots blotting IHC immunohistochemistry Parkinson's diseases cancers tumor-suppressive phosphatases tensin homologs dephosphorylates human signaling signalling pathway mRNA mitochondria c-terminus phosphatidyl inositols phosphates special:month specialdiscount:15 specialstart:2008-05-01 specialend:2008-05-31 immunoblotting 33.141270718232
11006 Piperlongumine 20069-09-4 ≥98% 2011-10-24 57.444354076548 piperlongumine Piplartine 2859-009- 11042-67-4 25343-05-9 Keap1 Nrf2 antioxidants ROS cancers redox platelet aggregation tumorigenesis 57.444354076548
13368 Piroxicam 36322-90-4 ≥95% 2010-01-06 3.501417463240 piroxicam NSC 666076; Larapam; Feldene inflammation NSAIDs inhibitors cyclooxygenases COX-1 COX-2 analgesic pain arthritis cancers Artrooxicam Baxo Bruxicam CP 16171 Geldene Neoxicam Reudene Roxicam Roxiden Sasulen Solocalm Uphaxicam Zunden inhibition inhibited inflammatory Piroxicam CP-16171 CP 16171 Feldene CP16171 3.501417463240
10728 PIT-1 Exclusive 53501-41-0 ≥98% ✓ 2011-03-25 11.615028182376 pit-1 PIP3 PtdIns-(3,4,5)-P3 PH domains cancers inhibitors Akt PDK1 PTENs proteins binding pituitary-specific transcription factors pit-1 pituitary-specific pit 1 GHF-1 GHF 1 pit-oct-unc pit oct unc POU growth hormones 11.615028182376
10459 PKC 412 120685-11-2 ≥98% 2010-07-27 25.560131929891 pkc-412 CGP 41251; N-Benzoylstaurosporine; Midostaurin; CGP 41231 inhibitors inhibits inhibition PKC412 PKC-412 serine/threonine serine threonine tyrosines kinases PKCα PKCβ PKCγ PKC-α PKC-β PKC-γ Syk Flk-1 Flk1 Akt PKA c-Kit cKit C-Fgr cFgr FLT3 FLT-3 PDFRβ PDFR-β VEGFR1 VEGF2 nitric oxide synthase eNOS apoptosis cancers angiogenesis signal transduction Staurosporine 25.560131929891
10011332 Plerixafor (hydrochloride hydrate) 155148-31-5 ≥98% 2009-02-10 177.592850828729 plerixafor-hydrochloride-hydrate Mobozil™; SID 791; JM 3100; AMD 3100 stem cells hematopoiesis HIV lymphocyte replication metastasis cancers growth antagonist CXCR4 SDF-1 SDF1 CXCL12 ireversible virus inhibits inhibition inhibitor 177.592850828729
13786 PMS2 Monoclonal Antibody (Clone 163C1251) - 2010-05-10 0E-12 pms2-monoclonal-antibody-clone-163c1251 PMS1 Protein Homologue 2; Mismatch Repair Endonuclease PMS2; DNA Mismatch Repair Protein PMS2 antibodies PMS-1 PMS 1 PMS 2 PMS-2 proteins DNA cancers HNPCC hereditary nonpolyposis non-polyposis western blots blotting immunoblotting WB cancer DNA damage repair 0E-12
11004 Podoplanin Monoclonal Antibody (Clone NZ-1.2) - 2011-08-05 0E-12 podoplanin-monoclonal-antibody-clone-nz-1-2 Aggrus; gp38; T1A mucin glycoproteins T1A gp38 aggrus tumors cells ligands CLEC-2 metastases tissues Th17 CD4+ humans PBMC antibodies 0E-12
11005 Podoplanin Monoclonal Antibody (Clone pmab-1) - 2011-08-05 0E-12 podoplanin-monoclonal-antibody-clone-pmab-1 gp38; Aggrus; T1A gp38 glycoproteins tissues lymphatic endothelial cells tumors lymphangiogenesis Th17 autoimmune diseases antibodies myelin antigens migration inflammation 0E-12
13198 PP2 172889-27-9 ≥98% 2010-09-20 28.396000000000 pp2 AGL 1879 PTK inhibitors inhibits inhibition Src kinase T cells T-cells enzymes AG1879 AG 1879 PP-2 PP 2 signalling tyrosine kinases tyrosine focal Tyr 577 adhesion kinases AG-1879 AGL1879 AGL 1879 thaliana Proteins Arabidopsis Proteins Arabidopsis thaliana Arabidopsis thaliana Proteins Hemagglutinins Plant Thale Cress Proteins Plant Hemagglutinins Arabidopsis Proteins Agglutinins Plant Plant Agglutinins Proteins Plant Phytagglutinins Plant Proteins Lectins Plant Plant Lectins 28.396000000000
13643 PP242 1092351-67-1 ≥95% 2011-04-22 13.905426934432 pp242 mTORs mTORC1 mTORC2 inhibitors cancer leukemia rapamycin PP 242 PP-242 inhibited inhibition 13.905426934432
11209 PRDM9 (human recombinant) Exclusive New - ≥65% ✓ 2012-01-11 24.814814814814 prdm9-human-recombinant PR Domain-containing Protein 9; MSBP3; ZNF899; PFM6; Meisetz histones methyltransferases zinc-fingers hotspots recombination genomes genetics meiosis trimethylation H3K4 nucleosomes PR/SET HTMase c-terminal C2-H2 PR domain zinc finger protein 9 24.814814814814
63520 PRIMA-1 5608-24-2 >95% 19.669569850039 prima-1 DNA binding anti-oncogenic apoptosis cancer p53 re-activator reactivator induces apoptotic re-activation reactivation antioncogenic cancers 2,2-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one 19.669569850039
10350 PRMT1 (human recombinant) - ≥80% 2011-01-25 112.131740860628 prmt1-human-recombinant Protein Arginine Methyltransferase 1 PRMT1 brucei Prmt1 TbPRMT1 brucei Silencing Factors Transcriptional Transcriptional Silencing Factors Transcription Factors Repressor Molecules Proteins Repressor Repressor Proteins arginine methyltransferase histones modification glycine arginine rich GAR motifs SAM-dependent GST-tagged active 112.131740860628
10750 PRMT4 (human recombinant) New - ≥70% 2011-12-21 9.138927255985 prmt4-human-recombinant Protein Arginine Methyltransferase 4; CARM1; Coactivator-associated Arginine Methyltransferase 1 PRMT arginine methyltransferases epigenetics PRMT4 CARM1 SAM MMA aDMA Arg-17 Arg-26 proteins enzymes catalytic domains S-adenosyl-L-methionine histones H3 binding binds p160 SRC-1 SRC1 GRIP1 TIF2 pCIP RAC3 ACTR AIB1 TRAM1 nuclear receptors phosphorylation Ser217 hormones regulation lipids metabolism ω-NG,NG-dimethylarginine ω-NG-monomethylarginine active 9.138927255985
13552 PRMT4 Polyclonal Antibody - 2009-07-24 0E-12 prmt4-polyclonal-antibody CARM1; Protein Arginine Methyltransferase 4 antibodies WB western immunoblotting blots coactivator associated arginine methyltransferase 1 steroids receptors SRC proteins co-activators blotting 0E-12
13559 PRMT5 Polyclonal Antibody - 2009-07-24 2.149650092081 prmt5-polyclonal-antibody Protein Arginine Methyltransferase 7; Skb1HS; JBP1 proteins PRMTs signaling WB western immunoblotting blots ADMA blotting janus kinase-binding kinase binding fission yeast 1 2.149650092081
10752 PRMT6 (human recombinant) New - ≥80% 2012-01-24 8.669677008074 prmt6-human-recombinant Protein Arginine Methyltransferase 6; HRMT1L6; Histone Arginine N-methyltransferase PRMT6; Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-like Protein 6 PRMTs arginine methyltransferases epigenetics PRMT6 histones SAM MMA aDMA H3R2 HMA H3K4 MLL HMGA1a active 8.669677008074
13558 PRMT6 Polyclonal Antibody - 2009-07-24 2.149650092081 prmt6-polyclonal-antibody Protein Arginine Methyltransferase 6 antibodies WB HeLa proteins western immunoblotting blots blotting 2.149650092081
13551 PRMT7 Polyclonal Antibody - 2009-07-24 1.842557221783 prmt7-polyclonal-antibody Protein Arginine Methyltransferase 7 PRMTs antibodies proteins western blotting immunoblotting blots SRC steroid receptor co-activator coactivator GRIP-1 GRIP1 WB 1.842557221783
10009762 Progesterone Receptor (Phospho-Ser190) Monoclonal Antibody - 2007-04-05 120.373149171270 progesterone-receptor-phospho-ser190-monoclonal-antibody antibodies WB western blots phospho-specific Progesterones receptors phosphorylation Ser190 cancers breast mammary glands endocrinology blotting immunoblotting IHC immunohistochemistry 120.373149171270
10009763 Progesterone Receptor (Phospho-Ser294) Monoclonal Antibody - 2007-04-05 120.373149171270 progesterone-receptor-phospho-ser294-monoclonal-antibody antibodies WB western blots phospho-specific progesterone receptors cancers breast mammary glands endocrinology blotting immunoblotting IHC immunohistochemistry 120.373149171270
13365 Programmed Cell Death Protein 4 (C-term) Blocking Peptide - 2008-08-25 0E-12 programmed-cell-death-protein-4-c-term-blocking-peptide PDCD4 antibodies antibody peptides antiserum antisera blocking immunoblotting WB western blots PDCD4 PCDC-4 PDCDP4 PDCDP-4 0E-12
10250 Programmed Cell Death Protein 4 (C-Term) Polyclonal Antibody - 2008-09-15 3.541574585635 programmed-cell-death-protein-4-c-term-polyclonal-antibody PDCD4; Neoplastic Transformation Inhibitor western blots WB KLH genes tumors antibodies antiserum antisera PDCD4 PCDC-4 PDCDP4 PDCDP-4 blotting immunoblotting 3.541574585635
500940 Progranulin (human) EIA Kit - 2011-04-26 31.976145346366 progranulin-human-eia-kit PGRN autocrine growth factor embryonic development tissues repair tumorigenesis inflammation signaling pathways cells cycles progressions motility precursor proteins secreted glycosylated forms proteolytic cleavages extracellular proteases peptides granulins GRNs paragranulin secretory leukocytes inhibitors SLPI periphery regulates regulation inflammatory cascade anti-inflammatory pro-inflammatory tumors necrosis factors receptors TNFRs TNF-alpha TNF-.alpha. TNF-a TNF-α TNFalpha TNF.alpha. TNFa TNFα pathogenesis arthritis mice mouse serum visceral obesity plasma glucose dyslipidemia central nervous systems CNSs neurotrophic activity neuroinflammation mutations genes chromosomes 17 frontotemporal lobar degeneration FTLD dementia marker chronic ELISAs EIAs enzymes immunoassays immunometrics assays cultures supernatants 31.976145346366
500950 Progranulin (mouse) EIA Kit - 2011-04-26 38.552602823818 progranulin-mouse-eia-kit murine mice PGRN autocrine growth factor embryonic development tissues repair tumorigenesis inflammation signaling pathways cells cycles progressions motility precursor proteins secreted glycosylated forms proteolytic cleavages extracellular proteases peptides granulins GRNs paragranulin secretory leukocytes inhibitors SLPI periphery regulates regulation inflammatory cascade anti-inflammatory pro-inflammatory tumors necrosis factors receptors TNFRs TNF-alpha TNF-.alpha. TNF-a TNF-α TNFalpha TNF.alpha. TNFa TNFα pathogenesis arthritis mice mouse serum visceral obesity plasma glucose dyslipidemia central nervous systems CNSs neurotrophic activity neuroinflammation mutations genes chromosomes 17 frontotemporal lobar degeneration FTLD dementia marker chronic ELISAs EIAs enzymes immunoassays immunometrics assays cultures supernatants 38.552602823818
10010 Prostaglandin A1 14152-28-4 >98% 146.280828729282 prostaglandin-a1 PGA1 prostaglandins renal vasodilation pge1 dehydration semen antimitotic antiproliferative 146.280828729282
9000184 Prostaglandin A1 methyl ester Exclusive 26771-94-8 ≥98% ✓ 2010-11-08 19.534551104972 prostaglandin-a1-methyl-ester PGA1 methyl ester hypertension cancers lipophilic analogs PGA1 prostaglandins 19.534551104972
12010 Prostaglandin D2 41598-07-6 ≥99% 162.543959850903 prostaglandin-d2 PGD2 Vasodilation prostaglandins brain sleep platelets aggregation. H-PGDS synthases mast cells hematopoietic allergic allergy asthmatic anaphylaxis hypotension inhibits inhibitors inhibition beta-trace .beta.-trace b-trace neurochemistry 162.543959850903
512031 Prostaglandin D2 EIA Kit - 2010-07-19 203.609714548802 prostaglandin-d2-eia-kit PGD2 ELISA Kit PGD2 prostaglandins measures kits eias enzyme immunoassays ELISAs measurements brains glutathione-independent lipocalin-type synthases L-PGDS cerebrospinal fluid CSF physiologic sleep rats humans mast cells leukocytes intracellular myeloid-type glutathione-dependent vascular 11β-PGF2α eicosanoids cultures lysates biosynthesis serum proteins albumin media medium methoximine derivatives PGD2-MOX competitive enzymatic reactions 203.609714548802
512041 Prostaglandin D2 Express EIA Kit - 2010-07-19 105.423217169570 prostaglandin-d2-express-eia-kit PGD2 Express ELISA Kit PGD2 prostaglandins measures kits eias enzyme immunoassays ELISAs measurements brains glutathione-independent lipocalin-type synthases L-PGDS cerebrospinal fluid CSF physiologic sleep rats humans mast cells leukocytes intracellular myeloid-type glutathione-dependent vascular 11β-PGF2α eicosanoids cultures lysates biosynthesis serum proteins albumin media medium methoximine derivatives PGD2-MOX competitive enzymatic reactions 105.423217169570
10007202 Prostaglandin D2 Lipid Maps MS Standard 41598-07-6 >99% 2008-10-27 15.401542711432 prostaglandin-d2-lipid-maps-ms-standard PGD2 Vasodilation prostaglandins brain sleep platelets aggregation. H-PGDS synthases mast cells hematopoietic allergic allergy asthmatic anaphylaxis hypotension inhibits inhibitors inhibition beta-trace .beta.-trace b-trace neurochemistry mass spectrometry standards GC LC MS 15.401542711432
10007939 Prostaglandin E Synthase-1 (microsomal) (human recombinant) - 16,000 x g supernatant 2009-03-15 26.335432780847 prostaglandin-e-synthase-1-microsomal-human-recombinant Membrane-Associated PGES-1; Prostaglandin H/E Isomerase; PIG12; mPGE Synthase-1; MGST1-L1 enzymes proteins PGs prostaglandins catalyzes conversion PGH2 PGE2 membrane-associated eicosanoids glutathiones metabolisms MAPEG expression proinflammatory stimuli stimulus IL-1.beta. IL-1b interleukins glucocorticoids synovial tissues primary synoviocytes rheumatiod arthritis fever onset drugs anti-inflammatory therapy therapies E. coli mPGES mPGES-1 mPGES1 active PTGES 26.335432780847
10009734 Prostaglandin E Synthase-1 (microsomal) Western Ready Control - 2007-05-01 10.028004143646 prostaglandin-e-synthase-1-microsomal-western-ready-control mPGE Synthase-1; PIG12; Memebrane-Associated PGES-1; Prostaglandin H/E Isomerase; MGST-L1 western blot WB prostaglandins renal failure synthase inhibitors mPGES mPGES-1 mPGES1 PTGES 10.028004143646
10011237 Protein Phosphatase 2A C subunit (human recombinant; L309 deletion) Exclusive - ✓ 2008-07-17 27.116464088398 protein-phosphatase-2a-c-subunit-human-recombinant-l309-deletion PP2A Cα; PP2A Δ309; PP2A L309 proteins phosphatases serine threonine cellular tumors enzyme kinetics regulations substrates phosphorylasion PP2As octahistidine-tag streptactin-tag active 27.116464088398
10010896 Protein Tyrosine Phosphatase 1B (human recombinant) - ≥95% 2008-08-25 11.069127071823 protein-tyrosine-phosphatase-1b-human-recombinant PTP1B proteins recombinant PTPs phosphates tyrosines pNPP enzymes diabetes insulin leptin signaling signalling active 11.069127071823
13527 Pseudolaric Acid B 82508-31-4 ≥98% 2009-12-04 5.961823204420 pseudolaric-acid-b PAB Pseudolarix kaempferi traditional Chinese fungal fungus infections cancers apoptosis angiogenesis tumors inhibits inhibitors inhibition P. therapy apoptosis cells 5.961823204420
10009817 PtdIns-(3,4,5)-P3 Binding Protein - ≥95% 2008-02-14 0.591560773480 ptdins-3-4-5-p3-binding-protein PI(3,4,5)-P3; Phosphatidylinositol-(3,4,5)-triphosphate; GRP1 PH Domain; PIP3 lipids recognition proteins GST-tagged PIPs phosphatidylinositols triphosphates 0.591560773480
10009815 PtdIns-(4,5)-P2 Binding Protein - ≥95% 2008-02-13 3.053911602210 ptdins-4-5-p2-binding-protein PIP2; PI(4,5)-P2; Phosphatidylinositol-(4,5)-diphosphate; PLC-δ1-PH Domain lipid recognition protein human recombinant GST-tagged proteins E. coli PIPs phosphatidylinositols diphosphate PLCdelta PLCd 3.053911602210
10009241 PtdIns-(4)-P1 Binding Protein - ≥90% 2008-02-21 0.591560773480 ptdins-4-p1-binding-protein SidC; PIP; PI(4)-P1; SidC 3C GST-tagged EDTA PIPs PtdIns phosphoinositols PIP2 PIP3 PI3-kinase cancers proteins 0.591560773480
10007073 PTEN Blocking Peptide - 2005-06-28 2.271712707182 pten-blocking-peptide Phosphatase and Tensin Homology on Chromosome 10 western blotting blots signaling signalling WB IHC immunohistochemistry formalin-fixed paraffin-embedded sections controls proteins dephosphorylates lipids AKT phosphatidylinositols triphosphates PIP3 tissues acids regulates cells division migrations apoptosis mutations cancers melanomas prostates carcinomas A431 HEK293 signals transductions 2.271712707182
10009746 PTEN (human recombinant) - ≥95% 2008-09-04 2.475679558010 pten-human-recombinant TEP1; Phosphatidylinositol 3-phosphatase; MMAC1; Phosphatase and Tensin Homology on Chromosome 10 proteins PTENs phosphatase homology tensin chromosomes enzymes lipids Sf21 cells recombinant N-terminal tumor suppressor cancers phosphoinositide hexahistidine His-tag His-tagged active 2.475679558010
10005059 PTEN Polyclonal Antibody - 2005-05-04 11.135635359116 pten-polyclonal-antibody TEP1; Phosphoinositide 3-phosphatase; MMAC1; Phosphatase and Tensin Homolog on Chromosome 10 proteins antibodies antisera antiserum wb western blots blotting IHC immunohistochemistry dephosphorylates lipids AKT phosphatidylinositols triphosphates PIP3 tissues acids regulates cells division migrations apoptosis mutations cancers melanomas prostates carcinomas A431 HEK293 signals transductions cancers endocrinology immunoblotting 11.135635359116
10009747 PTEN Western Ready Control - 2007-05-30 0.421731123388 pten-western-ready-control TEP1; MMAC1; Phosphatidylinositol 3-phosphatase; Phosphatase and Tensin Homology on Chromosome 10 western blot WB AKT phosphatidylinositol 3,4,5-triphosphate PIP3 enzyme transduction pathway endocrinology 0.421731123388
13000 Pterostilbene 537-42-8 ≥98% 2009-09-09 26.284175217048 pterostilbene 3',5'-Dimethoxy-4-Stilbenol; trans-3,5-Dimethoxy-4'-Hydroxystilbene resveratrol blueberries antioxidant PGE2 prostaglandins E2 cells proliferation ERK1/2 ERK 1/2 p38 MAPK PI3K/Akt NF-kB NFkB NF-κB NFκB AP-1 AP1 transcriptional activation cancers inflammation diabetes inflammatory 26.284175217048
10005169 Quercetin 117-39-5 >95% 2004-08-04 10.943977900552 quercetin flavonoid plants fruits glycosides carcinogens carcinogenic inhibits inhibitors inhibition phosphodiesterases antioxidants rutin 10.943977900552
10011620 Raloxifene (hydrochloride) 82640-04-8 ≥98% 2009-01-07 6.465676795579 raloxifene-hydrochloride Evista; LY156758; Keoxifene (hydrochloride) breasts cancers osteoporosis SERM estrogen evista bone remodeling formation IL-6 IL6 25-OH vitamin D parathyroid hormones cardiovascular protection 6.465676795579
13346 Rapamycin 53123-88-9 ≥95% 2009-10-21 44.025417638632 rapamycin Sirolimus immunosuppresssants transplants rejection inhibitors IL-2 lymphocytes B cells T FKBP12 mTOR mTORC1 cancer adipogenesis diabetes tuberous sclerosis cardiovascular diseases 44.025417638632
10947 RbBP5 (human recombinant) New - ≥90% 2012-01-06 14.152052839174 rbbp5-human-recombinant SWD1, Set1c WD40 repeat protein, homolog; Retinoblastoma binding Protein 5; RBQ3 epigenetics methyltransferases histones H3K4 genes regulation MLL proteins complex subunits nuclear WD40 domains tumors supressors RB cells proliferation E1A SET1 lysine MLL1 MLL1-4 dimethylation trimethylation H3 H3K4me2/me3 retinoblastoma-binding protein RBQ-3 RBBP-5 RBBP5 14.152052839174
10010172 (R)-Equol Exclusive 221054-79-1 ≥98% ✓ 2009-08-27 5.189150552485 -r-equol Isoequol; (+)-Equol phytoestrogens estrogens daidzen genistein receptors cancers R-Equol +equol + equol agonist activity R equol (R) equol 5.189150552485
10970 Retinoblastoma Protein (Cleaved) Monoclonal Antibody (Clone 172C1094) New - 2012-05-17 91.111111111111 retinoblastoma-protein-cleaved-monoclonal-antibody-clone-172c1094 p105-Rb; pp110; Rb; pRb tumors suppressors cells cycles regulators apoptosis cleavage caspase-3 likes proteases E2F-1 primary myeloid fetal livers bones marrow spleens cancer therapy therapies tumor-associated macrophages TAMs western blots blotting immunohistochemistry 91.111111111111
11017 Retinoic Acid 302-79-4 ≥98% 2011-10-25 17.543287906690 retinoic-acid ATRA; Tretinoin; NSC 122758; Vitamin A Acid; all-trans Retinoic Acid; NSC 122578 ligans receptor cancers development reproduction immunity gene expressions 7005-78-9 56573-65-0 187175-63-9 NSC-122758 NSC122758 AGN 100335 AGN100335 AGN-100335 aberel airol aknoten atragen cordes vas dermairol epi-aberel eudyna NSC 122578 NSC-122578 NSC122578 renova retacnyl retin A ro 1-5488 tretin M vesanoid vesnaroid vitamins A1 all trans 17.543287906690
10006606 Retreversine - >98% 2005-09-15 31.875870165746 retreversine inactive isomers reversine purine analogs cells stem organogenesis derivatives C2C12 myoblasts osteogenic bones adipogenic adipose de-differentiation dedifferentiation re-differentiation progenitors 31.875870165746
10004412 Reversine 656820-32-5 >98% 2005-03-25 40.351450276243 reversine purine analogs cells stem organogenesis derivatives C2C12 myoblasts osteogenic bones adipogenic adipose de-differentiation dedifferentiation progenitors fate cancers 40.351450276243
10010309 RG-13022 149286-90-8 ≥98% 2008-01-24 1.878891081294 rg-13022 protein tyrosine kinase PTK inhibitors inhibits inhibition antiproliferatives tyrphostin epidermal growth factors EGFs receptors cancers 1.878891081294
10010310 RG-14620 136831-49-7 ≥98% 2008-02-08 1.569600509987 rg-14620 protein tyrosine kinases PTKs inhibitors inhibits inhibition antiproliferative tyrphostin epidermal growth factors EGFs receptors proliferation cancers 1.569600509987
13293 Rhapontigenin Exclusive 500-65-2 ≥98% ✓ 2009-11-10 25.833729281767 rhapontigenin resveratrols antioxidants cancers cytochromes P450 CYP450 proliferation anti cancers anti-oxidants 25.833729281767
160785 RICK Polyclonal Antibody - 8.230653775322 rick-polyclonal-antibody Ripk2; Rip2; CARDIAK apoptosis antibodies kinase CARD domains RIP Fas western blots blotting WB antisera antiserum RIP-2 cancers immunoblotting CCK CCKs CCCK 8.230653775322
10006426 RITA 213261-59-7 >98% 2006-01-11 21.972860650705 rita NSC 652287; 2,5-bis(5-hydroxymethyl-2-thienyl) Furan HDM-2 human double minute-2 MDM-2 mouse murine negative regulator p53 proteasomal degradation tumors cancers apoptosis cells reactivation molecules inhibitors wild-type DNA-protein human renal SCID mice HCT116 A-498 xenografts nude HDM2 HDM-2 MDM2 21.972860650705
10765 RIZ1 (human recombinant) New - ≥95% 2012-05-02 76.169567428508 riz1-human-recombinant KMT8; Retinoblastoma Protein-interacting Zinc Finger Protein; PR Domain Zinc Finger Protein 2; PRDM2 epigenetics cancer Histone H3K9 PR Domain Zinc-Finger histones methyltransferases RIZ-1 RIZ 1 SAM-dependent RIZs tumor suppressor apoptosis methylation 76.169567428508
10311 (R)-(−)-Mellein New 480-33-1 ≥98% 2012-01-13 0.567164179104 -r-mellein Ochracin antibacterial antimalarial antifungal anticancer dihydroisocoumarin A. ochraceus wilhelm proliferation humans breasts cancers melanoma cells 21499-22-9 isocoumarin R-mellein MCF-7 MDA-MB-468 SK-MEL-28 (R)-mellein malme-3M 0.567164179104
13697 (R)-MG132 Exclusive 1211877-36-9 ≥98% ✓ 2010-06-22 102.382928176796 -r-mg132 ubiquitin proteasomes inhibitors proteolytic degradation inflammation cells cycle regulation cancers NF-κB apoptosis inhibition inhibited 102.382928176796
10006415 Ro 48-8071 161582-11-2 ≥98% 2005-06-01 8.098516179952 ro-48-8071 monooxidosqualenes cyclases inhibitors OSC cholesterols lowering activity microsomal enzymes catalyzes lanosterol synthetic pathway LDL low-density lipoproteins human livers microsomes HepG2 cells HDL high-desity toxicity CYP3A mRNA proteins hepatocytes cultures atherosclerosis 8.098516179952
11078 RORα Polyclonal Antibody (aa 220-270) New - 2012-04-19 104.444444444444 ror-polyclonal-antibody-aa-220-270 NR1F1; RAR-Related Orphan Receptor A; RZR-α receptors retinoic acids NR1 subfamily nuclear hormones DNA binding domains genes expression cells functions NM23-2 NM23-1 CDK7 NCOA3 NCOA6 coactivators mesenchymal stem cells bones marrow acute promyelocytic leukemia APL western blots blotting Nuclear Receptor RZR alpha Nuclear receptor RZR-alpha Nuclear Receptor RZR-alpha Nuclear receptor subfamily 1 group F member 1 Retinoid Related Orphan Receptor alpha Retinoid-related orphan receptor-alpha Retinoid-Related Orphan Receptor-alpha RZR alpha RZR-alpha, Nuclear Receptor nuclear receptor ROR-alpha retinoic acid receptor-related orphan receptor alpha RORalpha 104.444444444444
11077 RORα Polyclonal Antibody (aa 80-120) New - 2012-04-05 104.444444444444 ror-polyclonal-antibody-aa-80-120 receptors retinoic acids NR1 subfamily nuclear hormones DNA binding domains genes expression cells functions NM23-2 NM23-1 CDK7 NCOA3 NCOA6 coactivators mesenchymal stem cells bones marrow acute promyelocytic leukemia APL western blots blotting Nuclear Receptor RZR alpha Nuclear receptor RZR-alpha Nuclear Receptor RZR-alpha Nuclear receptor subfamily 1 group F member 1 Retinoid Related Orphan Receptor alpha Retinoid-related orphan receptor-alpha Retinoid-Related Orphan Receptor-alpha RZR alpha RZR-alpha, Nuclear Receptor nuclear receptor ROR-alpha retinoic acid receptor-related orphan receptor alpha RORalpha 104.444444444444
10009569 (R)-Roscovitine 186692-46-6 ≥98% 2007-09-04 18.619401473296 -r-roscovitine Seliciclib cell cycle cyclin-dependent kinase cdk proliferation cancer renal disease 18.619401473296
13664 S32826 1096770-84-1 ≥98% 2010-06-18 15.685453038674 s32826 Autotaxins lysophospholipase D lysophosphatidylcholine lysophosphatidic acids LPAs inhibitors src phosphatase 1B adipocytes plasma inhibited inhibition inhibits Esters, Phosphonic Acid Phosphonic Acid Esters Phosphonic Acids Phosphonates 15.685453038674
13603 S-Adenosylhomocysteine 979-92-0 ≥98% 2010-04-22 15.222591160220 s-adenosylhomocysteine SAH; AdoHcy amino acids derivatives cysteine methyl cycle biosynthesis risk factors metabolic pathways cancers by-products by products neurodegenerative diseases Adenosylhomocysteine, S S-Adenosylhomocysteine S Adenosylhomocysteine 15.222591160220
9000372 S-Adenosylhomocysteine-d4 Exclusive - ≥99% deuterated product ✓ 2009-12-02 19.547237569060 s-adenosylhomocysteine-d4 SAH-d4 deuteriums GC/MS LC/MS mass spectrometry GC-MS LC-MS deuterateds amino acids derivative cysteine methyl cycle biosynthesis 979-92-0 risk factors s-adenosyl-l-homocysteine-d4 19.547237569060
10009929 SAHA 149647-78-9 ≥98% 2007-08-07 111.847118621265 saha Vorinostat; Suberoylanilide Hydroxamic Acid; Zolinza™ HDACs inhibitors cancers inhibits inhibition 111.847118621265
13178 Salermide 1105698-15-4 ≥98% 2009-04-27 19.070710339384 salermide Sirtuin SIRT1 SIRT2 inhibitors cancers apoptosis leukemias histone deacetylases HDACS inhibition inhibited 19.070710339384
13628 Salidroside 10338-51-9 ≥97% 2010-05-28 17.793057090239 salidroside Rhodioloside glycosides plants Rhodiola Chinese medicine memory infections inflammation cancers diabetes fatigue apoptosis Glucosides 17.793057090239
13579 Salinomycin (sodium salt) 55721-31-8 ≥90% 2011-03-14 15.175138121547 salinomycin-sodium-salt cancers stem cells breasts inhibitors tumors anticancer pyrans anti-cancer inhibited inhibits inhibition CSCs 15.175138121547
13031 SB 431542 301836-41-9 ≥98% 2009-08-10 104.892580110497 sb-431542 inhibitors inhibits inhibitions TGF-β1 TGFβ1 receptors ALK5 ALK4 ALK7 ALKs BMP ALK2 ALK3 ALK6 kinases Smad fibrosis cancers renewal embryonic stems cells induced pluripotent differentiation SB431542 104.892580110497
10443 SB 939 New 929016-96-6 ≥98% 2012-02-06 7.126284948937 sb-939 Pracinostat inhibits inhibitions inhibitor HDACs pan-HDAC panHDAC SB939 SB-939 histones deacetylase proliferation voronistat cancers tumors SAHA ovarian A2780 colon COLO205 HCT-116 prostate PC-3 7.126284948937
10011561 SC-51089 146033-02-5 ≥95% 2010-02-02 10.908080110497 sc-51089 CID132748 prostaglandins E2 PGE2 receptors EP1 pain antagonists analgesia glioma cells cancers tumors growth neuroprotection neurons oxidative stress SC51089 SC 51089 PGs Oxazepines 10.908080110497
10876 SC-66 871361-88-5 ≥98% 2011-06-21 12.421801104972 sc-66 SC66 SC 66 analogs cyclohexanone curcumin cancers Akts inhibitors inhibits inhibition cancers ubiquitination cells death tumors tumorigenesis 12.421801104972
10010173 (S)-Equol 531-95-3 ≥98% 2009-08-27 10.549703038674 -s-equol 4',7-Isoflavandiol; 4',7-Dihydroxyisoflavan; (-)-Equol phytoestrogen estrogens daidzen genistein receptors cancers (S) equol S-equol -Equol (-) Equol antagonist 10.549703038674
10005260 Serine Palmitoyltransferase Polyclonal Antibody - 2004-12-02 27.109856353591 serine-palmitoyltransferase-polyclonal-antibody Serine-palmitoyl-CoA transferase, long chain base subunit 2; SPT antibodies antisera western blots blotting WB sphingolipids SPT2 immunohistochemistry immunohistochemical analysis IHC nuclear proteins nucleus immunoblotting 27.109856353591
13780 SET7/9 (FL) Polyclonal Antibody - 2010-03-08 6.526586863106 set7-9-fl-polyclonal-antibody SET Domain-Containing Protein; KMT7; SETD7/9 antibodies SET 7/9 SET-7/9 7 9 histones H3 lysines 4 western blotting WB blots immunoblotting 6.526586863106
10320 SET7/9 (human recombinant) - ≥95% 2009-08-11 24.024535383748 set7-9-human-recombinant KMT7; SETD7/9; SET Domain-containing Protein 7/9 SET-7/9 SET 7/9 7 9 recombinant His-tagged proteins SETs methylation methyltransferase active 24.024535383748
700270 SET7/9 Methyltransferase Inhibitor Screening Assay Kit - 2009-12-04 24.872556970425 set7-9-methyltransferase-inhibitor-screening-assay-kit methyltransferases SET Domain-containing Protein 7/9 lysines 7 KMT7 methylation signal transduction biosynthesis proteins repair genes silencing chromatins S-adenosylmethionine SAM AdoMet methyl donors Alzheimer's depression Parkinson's Diseases multiple sclerosis liver cancers substrates histones histone 3 lysine residue 4 H3K4 p53 transcription factors TAF10 mono-methylated mono-methylase DNA damage acetylation human tumorigenesis inhibitors acceptor peptides S-adenosylhomocysteine S-ribosylhomocysteine adenine nucleosidase hypoxanthine deaminase urate hydrogen peroxide H2O2 ADHP 10-acetyl-3,7-dihydroxyphenoxazine resorufin fluorescence measures measurement assays kits 24.872556970425
600490 SET7/9 SAM-Screener Assay Kit New - 2011-12-21 41.633066544674 set7-9-sam-screener-assay-kit SET7/9 SAM-Binding Site Inhibitor Screening kits assays measures measurements chromatins posttranslational modifications histones DNA deoxyribonucleic acids lysines methylations epigenetics regulations genomes mono-methyltransferases MTs domains S-adenosyl-L-methionines SAM AdoMet co-factors epsilons amino groups Dot1 KMT7 domain-containing non-histones H3 TAF10 p53 viral Tat estrogens receptors alpha .alpha. α substrates humans diseases catalytic catabolism fluorescence EpiTrek polarizations fluorescent probes binding pockets endogenous cofactors sinefungin peptides high-throughput 41.633066544674
10319 SET8 (human recombinant) - ≥95% 2010-01-07 16.373424505296 set8-human-recombinant SETD8; SET domain-containing (lysine methyltransferase) 8; KMT5a; PR-Set7 SET-8 SET 8 recombinant His-tagged proteins SETs methylation methyltransferase MTs domain containing active 16.373424505296
700350 SET8 Methyltransferase Inhibitor Screening Assay Kit - 2010-03-09 21.155178831055 set8-methyltransferase-inhibitor-screening-assay-kit SET domain-containing (lysine methyltransferase) 8; PR-Set7; SETD8 assays kits measures measurement methyltransferases MTs inhibits inhibitors inhibition methylation signal transduction biosynthesis protein repair genes silencing chromatins regulation S-adenosylmethionine (SAM)-dependent AdoMet DNA deoxyribonucleic acids Alzheimer's diseases depression Parkinson's multiple sclerosis livers cancers KMT5A lysines PR-Set 7 methylates histones H4 residues 20 H4K20 transcriptional p53 tumors suppressors tumorigenesis inhibits inhibition inhibitors peptides S-adenosylhomocysteines S-ribosylhomocysteines adenines nucleosidases hypoxanthines deaminases hydrogen peroxides H2O2 ADHP 10-acetyl-3,7-dihydroxyphenoxazines fluorescent fluorescence resorufin 21.155178831055
13332 (S)-Glycyl-H-1152 (hydrochloride) Exclusive 913844-45-8 ≥98% ✓ 2010-01-27 83.825403314916 -s-glycyl-h-1152-hydrochloride Rho Kinase Inhibitor IV Rho kinases ROCK-I p160ROCK ROCK-II G protein Rho cytoskeletons adhesions proliferation smooth muscles contraction stem cells inhibitors inhibition inhibited Fasudil hydrochloride ROCK IV h1152 h-1152 h 1152 83.825403314916
13277 (S)-HDAC-42 935881-37-1 ≥95% 2009-12-03 27.127075354659 -s-hdac-42 AR42 histones deacetylases HDACs cancers inhibitors prostate p21 Akt Bcl-XL tumors inhibition inhibits OSU-HDAC-42 27.127075354659
10006211 Silybin 22888-70-6 >98% 2005-02-16 16.013267561167 silybin Silymarin; Silibinin flavanoids flavonoids 5-LOs 5-lipoxygenases inhibits inhibitors inhibition flavonolignans Silybum marianum superoxides Kupffer cells leukotrienes LTB4 synthesis PMA-activated milk thistle 16.013267561167
10011190 SIRT1 (human recombinant) - ≥60% 2008-09-24 19.030764272559 sirt1-human-recombinant Silent Information Regulator 2; Sirtuin 1; SIR2-like Protein 1; SIR2L1; NAD-dependent Deacetylase 1 SIRT 1 SIRTs sirtuins HDACs DNA p53 proteins anti-cancers GST-tags GST-tagged sirtuin silent mating type information regulation 2 homolog 1 SIR2alpha sirtuin type 1 active 19.030764272559
700280 SIRT2 Direct Fluorescent Screening Assay Kit - 2009-12-10 40.755135213724 sirt2-direct-fluorescent-screening-assay-kit Nucleosomes chromosomal deoxyribonucleases DNA histones H2A H2B H3 H4 octameric cores transcription amino termini acetylation phosphorylation methylation ε-amino lysines acetyltransferases HATs chromatins genes activation deacetylases HDACs catalyzes hydrolytic acetyls sirtuins trichostatins A-insensitive lysyl-deacetylases class III catalyzes deacetylation nicotinamides O-acetyl-ADP-ribose NAD+ human SIRT1 SIRT2 SIRT3 SIRT4 SIRT5 SIRT6 SIRT7 cytoplasmic proteins H4 lysine-16 lysine-40 α-tubulin a-tubulin alpha-tubulin HDAC6 microtubules mitotic chromosomal hyperpolid cells tissues skeletal muscle heart oligodendroglia brain tumor suppressor gliomas Down-regulation gene chromosomal region diagnostic marker fluorescence-based inhibitors activators p53 Gln-Pro-Lys-Lys(ε-acetyl)-AMC recombinant NAD+ fluorescent fluorescence kits assays measures measurement 40.755135213724
10011191 SIRT2 (human recombinant) - ≥90% 2009-07-31 16.713987108655 sirt2-human-recombinant Silent Information Regulator 2; Sirtuin 2; SIR2-like Protein 2; NAD-dependent Deacetylase 2; SIR2L2 SIRT 2 SIRTs sirtuins HDACs DNA p53 proteins anti-cancers His-tagged His tag sirtuin silent mating type information regulation 2 homolog 2 sirtuin type 2 active 16.713987108655
10011194 SIRT3 (human recombinant) - ≥90% 2008-12-15 25.532397790055 sirt3-human-recombinant SIR2L3; Mitochondrial Nicotinamide Adenine Dinuclear-dependent Deacetylase; SIR2-like Protein 3; NAD-dependent Deacetylase 3; Silent Information Regulator 3; Sirtuin 3 SIRT 3 SIRTs sirtuins HDACs DNA p53 proteins anti-cancers GST-tags GST-tagged sirtuin silent mating type information regulation 2 homolog 3 sirtuin type 3 sir2-like 3 active 25.532397790055
10317 SIRT4 (human recombinant) - ≥95% 2010-01-06 9.452173112338 sirt4-human-recombinant Sirtuin 4; Silent Information Regulator 4; SIR2L4; SIR2-like Protein 4; NAD-dependent ADP-ribosyltransferase Sirtuin 4 SIRTs Sirtuins HDACs proteins His-tagged hexahistidines HDACS histone decatylases GDH glutamate dehydrogenase sirtuin silent mating type information regulation 2 homolog 4 sirtuin type 4 9.452173112338
10318 SIRT5 (human recombinant) - ≥90% 2009-07-31 18.494220994474 sirt5-human-recombinant Silent Information Regulator 5; Sirtuin 5; SIR2L5; SIR2-like Protein 5; NAD-dependent Deacetylase 5 SIRTs proteins HDACs CSP1 GST-tagged silent mating type information regulation 2 homolog 5 sirtuin type 5 18.494220994474
700290 SIRT6 Direct Fluorescent Screening Assay Kit - 2010-02-18 37.424678867403 sirt6-direct-fluorescent-screening-assay-kit SIRT 6 SIRT-6 assays kits measures sirtuins trichostatins A-intensive lysyl-deacetylases class III HDACs human mitochondrial nuclear proteins mitochondrias translocated nucleus cells cellular stress lysine deacetylation nicotinamides O-acetyl-ADP-ribose NAD+ abstracted ADP-ribosyl transferases deacetylases telomeres chromatins NF-κB NF-kappaB NF-.kappa.B signaling signalling mammalian cells Werner Syndromes aging disorders anti-cancers anti-inflammatory drugs apoptosis screening fluorescence activators Arg-His-Lys-Lys(ε-acetyl)-AMC fluorescent fluorometric 37.424678867403
10315 SIRT6 (human recombinant) - ≥95% 2009-07-31 16.179944751381 sirt6-human-recombinant Sirtuin 6; NAD-dependent Deacetylase 6; Silent Information Regulator 6; SIR2L6; SIR2-like Protein 6 SIRTs Sirtuins HDACs proteins His-tagged hexahistidine silent mating type information regulation 2 homolog 6 sirtuin type 6 active 16.179944751381
10316 SIRT7 (human recombinant) - ≥85% 2009-12-22 13.922508287293 sirt7-human-recombinant SIR2L7; Sirtuin 7; Silent Information Regulator 7; SIR2-like protein 7; NAD-dependent deacetylase 7 SIRTs Sirtuins HDACs proteins His-tagged hexahistidine histone deacetylases silent mating types information regulators 2 homologs 13.922508287293
10523 Sirtinol New 410536-97-9 ≥98% 2012-03-29 42.270114942529 sirtinol Sir Two Inhibitor Naphthol inhibitors inhibits inhibition histones deacetylases sirtuins cancers inflammation plants biology cells NAD+ yeast Sir2p humans 42.270114942529
10822 SMAD1/5/8/9 Polyclonal Antibody - 2011-04-14 0.753496448303 smad1-5-8-9-polyclonal-antibody WBs western blots immunoblotting SMADs 1 5 8 9 SMAD-1-5-8-9 1/5/8/9 antibodies serum 1,5,8,9 0.753496448303
10821 SMAD1/5/8/9 Polyclonal Antiserum - 2011-03-31 0.753496448303 smad1-5-8-9-polyclonal-antiserum WBs western blots immunoblotting SMADs 1 5 8 9 SMAD-1-5-8-9 1/5/8/9 antibodies serum 0.753496448303
10823 SMAD2 Polyclonal Antibody - 2011-05-05 0.753496448303 smad2-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-2 SMAD 2 antibodies serum IHC immunohistochemistry TGF-β TGFβ cancers 0.753496448303
10832 SMAD3 Polyclonal Antibody - 2011-05-03 0.659309392265 smad3-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-3 SMAD 3 antibodies serum IHC immunohistochemistry TGF-β TGFβ Tcells signaling TGF-β MH1 domains DNA proteins SARA ECM apoptosis proliferation differentiation 0.659309392265
10838 SMAD4 Polyclonal Antibody - 2011-05-05 2.900856353591 smad4-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-4 SMAD 4 antibodies serum IHC immunohistochemistry TGF-β TGFβ cancers 2.900856353591
10839 SMAD6 Polyclonal Antibody - 2011-05-02 1.814269928965 smad6-polyclonal-antibody WBs western blots immunoblotting SMADs MAD SMAD-6 SMAD 6 antibodies serum IHC immunohistochemistry TGF-β TGFβ Tcells intracellular proteins signaling serine threonine apoptosis bones cancers genes signal transduction 1.814269928965
10845 SMAD7 Polyclonal Antibody - 2011-05-05 0.753496448303 smad7-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-7 SMAD 7 antibodies serum TGF-β TGFβ Tcells 0.753496448303
10840 SMAD7 Polyclonal Antibody (azide-free) - 2011-05-05 1.950055248618 smad7-polyclonal-antibody-azide-free WBs western blots immunoblotting SMADs SMAD-7 SMAD 7 antibodies serum TGF-β TGFβ Tcells 1.950055248618
10012628 (S)-MG132 133407-82-6 ≥98% 2009-02-18 179.218132596685 -s-mg132 Z-Leu-Leu-Leu-CHO ubiquitin proteasome inhibitors inhibits inhibition proteolytic degradation inflammation cell cycle regulation cancers NF-kB NFkB apoptosis NF-κB mg 132 mg-132 2-LLL-CHO 179.218132596685
11029 SMI-4a New 327033-36-3 ≥95% 2012-03-14 20.000000000000 smi-4a serine/threonine kinases Pim cancers rapamycin-sensitive mammalian target of rapamycin mTORC1 AMPK leukemia inhibitors inhibits inhibition SMI4a SMI 4a cells myeloid lymphoid T-cells T cells lymphoma apoptosis tumors Ser/Thr 20.000000000000
13121 Sodium Butyrate 156-54-7 ≥95% 2009-07-31 57.741817065684 sodium-butyrate Butyric Acid (sodium salt) fatty acids short chains inhibitors inhibits inhibition histones deacetylases HDACs epigenetics growth arrest differentiation apoptosis cancers inflammation genes expressions pro-inflammatory proinflammatory cytokines IFN-γ IL-6 IFNγ IL6 IL-1β IL1β IFNg 57.741817065684
10010466 SP 600125 129-56-6 ≥98% 2009-01-07 11.780883977900 sp-600125 1PMV; Pyrazolanthrone; NSC 75890 c-Jun cJun JNKs inhibitors inhibits inhibition reversible cell-permeable cells COX-2 COX2 MAP kinase MAPK genes expressions apoptosis autophagy differentiation IL-10 IL10 TNF-α TNFα IFN-γ IFNγ T-cells Tcells HeLa sp600125 11.780883977900
10348 Sphingosine Kinase 1 (human recombinant) - ≥90% by SDS-PAGE 2011-04-12 43.316690105475 sphingosine-kinase-1-human-recombinant SPHK1; SK1 sphingosines phosphates ceramides apoptosis acids cells death kinases sphingomyelin growth calcium active 43.316690105475
700430 Sphingosine Kinase 1 Inhibitor Screening Assay Kit - 2010-09-16 46.168646408839 sphingosine-kinase-1-inhibitor-screening-assay-kit SPHK 1 kits assays measures measurements SK1 SPHK1 sphingolipids metabolic pathways phosphorylates D-erythro-sphingosines sphingosine-1-phosphates S1P cells proliferations migrations cytoskeletal morphogenesis SPHK2 2 mammalian signalling signaling masts TNF-a TNFa TNF-alpha TNFalpha TNF-α TNFα-triggered Tumors Necrosis Factor-α fibroblasts epithelial mRNA messenger ribonucleic acids levels brains oncogenics erythroleukemias therapy therapeutics cancers inflammation up-regulated phagocytes peritoneal sepsis mice murine mouse inhibition inhibitors inhibits septic shock fluorescence-based fluorescent ATP adenosine triphosphates phosphorylates phosphorylation C-18 ADP diphosphates hydrogen peroxides H2O2 resorufin 46.168646408839
10006822 Sphingosine Kinase 1 Polyclonal Antibody - 2006-12-21 23.619964088397 sphingosine-kinase-1-polyclonal-antibody SPHK 1 proteins diseases antibodies antisera antiserum WB western blots blotting ICC immunocytochemistry sphingosines kinases enzymes sphingolipids metabolisms catalyzes phosphorylation sphingosine-1-phosphates cells proliferation death tissues kidneys livers spleen hearts platelets tumors cytosolic membranes amino acids post translational modifications SK1 SPK1 cancers immunoblotting 23.619964088397
10012201 Sphingosine Kinase 1 Polyclonal FITC Antibody Exclusive - ✓ 2008-06-06 0.590607734806 sphingosine-kinase-1-polyclonal-fitc-antibody SPHK 1 SPHK-1 metabolism sphingolipids phosphorylation sphingosine-1-phosphate cell proliferation death immunofluorescence IF flow cytometry FC western blots WB SPHKs blotting immunoblotting 0.590607734806
10009237 Sphingosine Kinase 2 (human recombinant) - >80% by SDS-PAGE 2007-01-18 34.970201262825 sphingosine-kinase-2-human-recombinant SPHK 2; SK2 signalling inflammatory enzymes proteins GenBank Accession No AF245447 SK2 SPK2 kinases sphingolipids SPHKs D-erythro-sphingosines phosphorylates sphingosine-1-phosphates S1Ps isoforms mammalian cells signals signaling pathways cancers inflammation proliferation apoptosis calcium homeostasis angiogenesis vascular maturation diseases active 34.970201262825
10009222 Sphingosine Kinase Inhibitor 2 312636-16-1 ≥95% 2007-01-18 33.660262430938 sphingosine-kinase-inhibitor-2 SKI II; SPHK 2 cancers Anti-proliferative Sphingosine-1-phosphates S1Ps SK1 SK2 SKI2 SPHK1 SPHK2 sphingosines sphingolipids inhibits inhibitors inhibition proliferation 33.660262430938
13084 STF-62247 315702-99-9 ≥98% 2009-10-07 33.988508287293 stf-62247 autophagy lethality renal cells carcinoma cancers von Hippel-Lindau VHL tumors supressors genes growth rates kidneys metastasize syndrome diseases 33.988508287293
13338 SU 6656 330161-87-0 ≥95% 2009-08-04 23.932662983425 su-6656 inhibitors Src kinases Src Yes Lyn Fyn cells growth development nervous system fibrosis cancers inhibits inhibition CNS SU6656 23.932662983425
10574 Suberohydroxamic Acid 38937-66-5 ≥98% 2010-09-28 21.781184392264 suberohydroxamic-acid SBHA; Suberic bis-Hydroxamic Acid histones deacetylases HDACs inhibitors genes expression regulation epigenetics nucleosomes HDAC1 HDAC3 differentiation cells cycle arrest apoptosis cancers suberodihydroxamic acid suberoyl bishydroxamic acid inhibited inhibition Warner-Lambert Brand of Mefenamic Acid Warner Lambert Brand of Mefenamic Acid Pharmascience Brand of Mefenamic Acid First Horizon Brand of Mefenamic Acid Parke Davis Brand of Mefenamic Acid Farmasierra Brand of Mefenamic Acid Ashbourne Brand of Mefenamic Acid Pinewood Brand of Mefenamic Acid Nu-Pharm Brand of Mefenamic Acid Nu Pharm Brand of Mefenamic Acid Chemidex Brand of Mefenamic Acid Gödecke Brand of Mefenamic Acid Clonmel Brand of Mefenamic Acid Antigen Brand of Mefenamic Acid Pfizer Brand of Mefenamic Acid Apotex Brand of Mefenamic Acid Rowa Brand of Mefenamic Acid Elan Brand of Mefenamic Acid APS Brand of Mefenamic Acid PMS-Mefenamic Acid PMS Mefenamic Acid Acid Mefenaminic Mefenaminic Acid Acid Mefenamic Mefenamic Acid Forte Ponstan Ponstan Forte Apo-Mefenamic Apo Mefenamic Nu-Mefenamic Nu Mefenamic ApoMefenamic NuMefenamic Pinalgesic Contraflam Ponalgic Parkemed Ponstel Ponstan Ponalar Mefacit Pontal Ponsyl Ponmel Dysman Coslan Mefic Mefac 21.781184392264
10928 SUCNR1 Polyclonal Antibody - 2011-11-03 0.904972375691 sucnr1-polyclonal-antibody GPR91 membranes receptors G-proteins coupled 1 family cells communications citric acids cycles succinate developments injury angiogenic factors VEGF proliferative ischemic retinopathy diabetic Western blots blotting immunohistochemistry IHC WB SUCNR-1 SUCNRs 0.904972375691
10763 SUV4-20H1 (human recombinant) - ≥60% 2011-07-13 32.081229281768 suv4-20h1-human-recombinant KMT5B; Suppressor of Variegation 4-20 Homolog 1; Lysine N-methyltransferase 5B methyltranferases histones H3K20 SET-domain containing s-adenosylmethionine s-adenosylhomocysteine lysines methylation epigenetics genes regulations KMT5B trimethylation H4K20 GRIP1 KMT5C KMT-5B KMT-5C KMTs active 32.081229281768
10764 SUV4-20H2 (human recombinant) - ≥95% 2011-06-06 32.572251381215 suv4-20h2-human-recombinant Suppressor of Variegation 4-20 Homolog 2; KMT5C methyltransferases histones H3K20 SET-domain containing s-adenosylmethionine s-adenosylhomocysteine lysine methylation epigenetics genes regulation SETD8 Pr-SET7 SUV420H2 SUV-420H2 SUV 420H2 SUV420H1 SUV-420H1 SUV 420H1 active 32.572251381215
16860 Swainsonine 72741-87-8 ≥98% 2009-06-12 121.991995089011 swainsonine Tridolgosir Alkaloid N-linked glycoside hydrolases asparagine-linked glycoproteins glycoproteins inhibitor lysosomal α-mannosidase glycosidases Golgi α-mannosidase II N-linked glycosylation antiproliferative proliferation growth antimetastatic metastasis cancer α-mannosidase lysosomes oligosaccharides glycoproteins lysosomal storage disease toxicity locoism 121.991995089011
13258 Tamoxifen 10540-29-1 ≥98% 2010-01-21 75.908419802325 tamoxifen nuclear receptors 17β-estradiol estrogen ERα ERβ modulators antagonists breast cancers tumors agonists bones osteoporosis cardiovascular disease menopause women uterus uterine endometrial carcinomas Nolvadex Istubal Valodex Savient brand of Tamoxifen Citrate Citrate Tamoxifen Tamoxifen Citrate Zitazonium Tomaxithen ICI-4 474 ICI 46 474Tamoxifen ICI-47699 ICI-46474 ICI46474ICI 47699 ICI 46474 Soltamox Novaldex Nolvadex ICI47699 ICI46474 75.908419802325
11629 Tamoxifen (citrate) New 54965-24-1 ≥98% 2012-04-04 71.420949142938 tamoxifen-citrate ICI 46474; Nolvadex; Istubal; Noltam; Kessar; TMX; Valodex; Zemide 7244-97-5 I.C.I.46474 citrate tamofen tamoplex tamox-puren tomaxasta Z-tamoxifen citrate nourytam ICI-46474 ICI46474 estrogen receptors cancers breasts agonists antagonists cholesterol modulators ER adjuvants bones uterus tissues cytochromes P450 CYP450 endoxifen cells apotosis autophagy differentiation 71.420949142938
10009911 Tangeritin 481-53-8 ≥98% 2008-12-16 11.780883977900 tangeritin Ponkanetin; NSC 618905; NSC 53909 flavone cancers tumors cholesterol atherosclerosis ERKs p38 MAPKs JNKs AKTs LDLs triacylglycerol estradiol MDR1 pregnane X receptors IL-1 IL1 IL 1 melanoma insulinoma 11.780883977900
13085 Tenovin-1 Exclusive 380315-80-0 ≥98% ✓ 2008-09-18 26.669751381215 tenovin-1 histones sirtuins cancers p53 cell growth tumors SIRT1 SIRT2 inhibitors inhibits inhibition melonoma lymphoma 26.669751381215
13086 Tenovin-6 1011557-82-6 ≥95% 2009-02-12 42.828153117600 tenovin-6 histones sirtuins cancers p53 cell growth tumors SIRT1 SIRT2 inhibitors inhibits inhibition SIRTs transcription factors TFs 42.828153117600
11443 Tenuazonic Acid New 610-88-8 ≥98% 2012-04-24 77.115472019033 tenuazonic-acid AAC-toxin L-Tenuazonic acid 16818-18-1 128892-49-9 Alternaria mycotoxins food egg chicken embryos esophagus esophageal cancers humans mice mouse precancerous lesions mucosa epithelial cells pyknosis pleomorphisms nuclei chromatins granulations mass irregularities nuclear contours vacuolizations nucleoplasms contaminants contaminations 77.115472019033
10011619 Terbinafine (hydrochloride) 78628-80-5 ≥98% 2010-02-16 4.223204419890 terbinafine-hydrochloride antifungals squalene epoxidase antitumor tumors antiangiogenic anticancer cancers inhibitors inhibits inhibition Naphthalenes 4.223204419890
10007565 Tetradecyl Phosphonate 4671-75-4 >98% 2005-10-17 49.791160220994 tetradecyl-phosphonate pan-antagonists LPA receptors lysophosphatic acids lipids signalling molecules hydrolysis lysophospholipase D autotoxin signals GPCRs G-protein coupled LPA1/EDG-2 LPA2/EDG-4 LPA3/EDG-7 LPA4/GPR23 activates activation PPAR.gamma. peroxisomes proliferator-activated inhibits inhibition LPA-induced calcium mobilization activates reporter 49.791160220994
70302 tetramethyl Nordihydroguaiaretic Acid Exclusive 24150-24-1 ≥98% ✓ 2008-09-24 27.192639656230 tetramethyl-nordihydroguaiaretic-acid tetramethyl NDGA; TMNDGA; Tetrameprocol; M4N; EM-1421 tumors inhibitor inhibits inhibition cancers NDGAs survivin apoptosis Cdc2 HIV growing growth glioma brains antitumor organic melonomas 27.192639656230
10007207 tetranor-12(S)-HETE 121842-79-3 ≥98% 2005-12-07 29.745690607734 tetranor-12-s-hete neuroscience peroxisomes metabolites arachidonic acids metabolisms 12-lipoxygenases 12-LOs platelets leukocytes smooth muscle cells tumors adhesion endothelial fibronectin subendothelial matrix b-oxidation .beta.-oxidation tissues Lewis lung carcinomas controlling inflammations inflammatory responses injured corneas Zellweger's syndromes peroxisomal abnormalities inability metabolizes symptoms diseases derivatives reasearch tools elucidations metabolic fate cancers ophthalmology 29.745690607734
10522 Thapsigargin 67526-95-8 ≥97% 2011-09-23 50.668617447869 thapsigargin calcium, ATPases, sarco/endoplasmic calcium ATPases SERCAs cells signaling activation histamine cancers tumorigenesis inflammation reticula sarcoplasmic endoplasmic 50.668617447869
10009813 thio-Miltefosine - >98% 2007-08-13 7.149613259669 thio-miltefosine analogs inhibitors inhibit inhibition CTP phosphocholine cytidylyl transerases antimetastatic antiproliferatives ceramides apoptosis antiprotazoal thiomiltefosine sulfurs thios 7.149613259669
10783 TIP60 (human recombinant) New - ≥80% 2012-02-27 13.967022262195 tip60-human-recombinant Hs.6364; HIV-1 Tat Interacting Protein 60 kDa; Esa1; HTATIP; cPLA(2) Interacting Protein; KAT5; PLIP histones acetyl transferases HATs KAT5 KATs lysine acetyltransferases Tip-60 epigenetics histones modifications MYST Ataxia Telangiectasia Mutants p400 complex γH2AX iTIP60 Tip-60 13.967022262195
10038 TMS 24144-92-1 >98% 38.985359116022 tms 2,3',4,5'-Tetramethoxystilbene cytochromes inhibitors tetramethoxystilbene antimutagenesis CYP450-1B1 inhibits selective selectivity apoptosis cell growth 38.985359116022
11105 TNF Receptor-Associated Protein 1 (human recombinant) New - ≥95% 2011-11-29 1.828038674033 tnf-receptor-associated-protein-1-human-recombinant Hsp90L; Hsp75; TRAP1; Mitochondrial Heat Shock Protein 75 kDa metabolism insulin non-insulin-dependent (type 2) diabetes mellitus glucose kinases tumors necrosis factor type 1 receptors-associated proteins TNFR-associated protein 1 ATP mitochondrial HSP90 heat shock ATPase cancers cardiomyocytes geldanamycin SNX-0723 SNX0723 SNX 0723 TNFR1 1.828038674033
700240 Total Phosphatidic Acid Assay Kit - 2009-08-24 69.939443567482 total-phosphatidic-acid-assay-kit PA Assay Kit assays kits measures fluorescence-based cells cellular phospholipids phosphatidate membranes storage de novo synthesis phospholipases PLD PLA hydrolysis phosphodiesters phosphatidylcholines PC phosphorylation diacylglycerol DAG DAGK lysophosphatidic LPA lysoPA-acyltransferase LPAAT phosphates phosphohydrolases LPPs intracellular signal transduction mammalian rapamycin mTOR signaling cycle progression growth disregulation human diseases cancers bacterial FKBP12 Raf-1 kinases sphingosines cAMP Adenosines 3',5' cyclic mononucleotides phosphodiesterases 4A1 translocation proteins PKC tyrosines SHP-1 guanine nucleotides Son of sevenless glycerol-3-phosphate oxidized oxidases hydrogen peroxides H2O2 peroxidases ADHP 10-acetyl-3,7-dihydroxyphenoxazines resorufin 69.939443567482
160750 TRAIL Polyclonal Antibody - 0E-12 trail-polyclonal-antibody Apo-2L apoptosis cell death TNF DR4 DR5 NF-.kappa.B NF-kappab NF-kappab antisera antiserum antibodies WB western blots blotting cancers immunoblotting 0E-12
9000784 (−)-trans-C75 Exclusive 1234694-22-4 ≥98% ✓ 2011-07-20 8.457845303867 -trans-c75 (2S,3R)-C75 trans C75 transC75 inhibitors inhibits inhibition fatty acids synthases FAS apoptosis cancers obesity C-75 apoptosis 8.457845303867
9000783 (+)-trans-C75 Exclusive 1234694-20-2 ≥98% ✓ 2011-07-20 8.457845303867 -trans-c75 (2R,3S)-C75 transC75 trans C75 fatty acids synthases FAS apoptosis cancers obesity inhibitors inhibits inhibition C-75 8.457845303867
10188 trans-trismethoxy Resveratrol 22255-22-7 >98% 2004-03-03 17.890565235869 trans-trismethoxy-resveratrol (E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzene diol selective cyclooxygenases inhibitors COX-1 PGHS-1 COX1 PGHS Prostaglandins synthases antioxidants oxidative injury stress sirtuins 3,5,4'-trihydroxy stilbene 3,5,4'-trihydroxystilbene 3,5,4'-trimethoxy stilbene 3,5,4'-trimethoxystilbene trimethoxy AHR antagonists aryl hydrocarbon receptors 17.890565235869
13129 trans-trismethoxy Resveratrol-d4 - ≥99% deuterated product 2009-02-09 18.326800184162 trans-trismethoxy-resveratrol-d4 (E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzene diol-d4 deuterated deuterium GC/MS GC-MS LC/MS LC-MS mass spectrometrysirtuins AHR antagonists aryl hydrocarbon receptors 18.326800184162
13791 TRF2 Polyclonal Antibody - 2010-06-24 0.690607734806 trf2-polyclonal-antibody TTAGGG Repeat Binding Factor 2; TRBF2; Telomeric Repeat Binding Factor 2; TERF2 antibodies proteins TRF-2 TRF 2 factors repeat DNA binding cells apoptosis western blots blotting immunoblotting telomere WB ICC IP ChIP IF immunoprecipitation immunofluorescence immunocytochemistry cancers apoptosis 0.690607734806
89730 Trichostatin A 58880-19-6 ≥98% 76.189505875335 trichostatin-a TSA reversible inhibitors histone deacetylase nuclear receptors inhibitions inhibits hdacs TSAs cancers 76.189505875335
10010237 Triciribine 35943-35-2 ≥98% 2007-09-11 6.821546961326 triciribine Tricyclic Nucleoside; NSC 154020; API 2 Akt cancers inhibitors inhibition inhibits Akt-1 Akt1 Akt-2 Akt2 Akt-3 Akt3 PI3-kinase PI3kinase PI3K PI-3-kinase phosphorylation activation signalling pathway signaling 6.821546961326
10009083 Trimidox Exclusive 95933-74-7 ≥98% ✓ 2008-02-13 4.169060773481 trimidox VF 233 apoptosis ribonucleotide reductases cells cycles cancers dNTP HIV caspase DNA synthesis chemotherapy dGTP HL-60 4.169060773481
10011124 Trimidox (hydrochloride) Exclusive - >98% ✓ 2008-06-10 4.169060773481 trimidox-hydrochloride CF 233 (hydrochloride) apoptosis ribonucleotides reductases cells cycles cancers dNTP HIV caspases DNA synthesis chemotherapy dGTP HL-60 HCls 4.169060773481
10011659 Trolox 53188-07-1 ≥98% 2008-12-02 311.238232044199 trolox 6-hydroxy-2,5,7,8-tetramethylchroman-2-Carboxylic Acid antioxidants vitamins E oxidative injury injuries neurodegeneration aging cancers adjunctive 311.238232044199
11445 Tunicamycin New 11089-65-9 ≥95% (mixture of isomers) 2012-05-01 81.758023750555 tunicamycin 11118-26-6 N-linked glycosylation post-translational modifications proteins folding inhibitors inhibition inhibits antibiotics glycoproteins EGFR ErbB2 ErbB3 IGF-IR ALK cancers palmitoylation oligomerization cells endoplastic reticulum amino acids Golgi plasma membranes nucleoside U251 glioma BXPC3 phosphorylation 81.758023750555
10072 Ursolic Acid New 77-52-1 ≥98% 2012-02-29 94.444444444444 ursolic-acid NSC 4060; Prunol; NSC 167406; Malol; Bungeolic Acid; Maerotaine NSC-167406 NSC167406 NSC-4060 NSC4060 neoage UR ursolisome urson β-Ursolic 209545-05-1 triterpenoid antioxidative antimicrobial anti-inflammatory anticancer Na+ K+ ATPase NF-kB cells proliferation apoptosis inhibitions inhibitors inhibits inflammation cancers 94.444444444444
10774 UTX (human recombinant) - ≥85% 2011-05-24 19.139403519541 utx-human-recombinant Ubiquitously Transcribed Tetratricopeptide Repeat X; KDM6A epigenetics histones lysines demthylases chromatins regulators dioxygenases JmjC proteins enzymes recombinants UTY genes chromosomes active 19.139403519541
13033 Valproic Acid (sodium salt) 1069-66-5 ≥95% 2009-10-21 32.904732965009 valproic-acid-sodium-salt Sodium Valproate; 2-Propylvaleric Acid valeric acids anticonvulsant seizures inhibitors histones deacetylases HDAC glycogen synthase kinases GSK3 inositol-1,4,5-trisphosphate IP3 combination therapy cancers Alzheimer's diseases stem differentiation self-renewal 32.904732965009
160840 VE-Cadherin Polyclonal Antibody - 21.078121546961 ve-cadherin-polyclonal-antibody Cadherin-5; CD144 Western blots blotting antibodies WB antisera antiserum ICC IP immunocytochemistry immunoprecipitation apoptosis cancers immunoblotting 21.078121546961
13131 VER-49009 Exclusive 940289-57-6 ≥98% ✓ 2010-07-09 4.866372007366 ver-49009 heat shock proteins Hsp90 inhibitors Hsp27 Hsp72 cells cycle arrest apoptosis inhibits inhibition isoxazole survivin C-RAF B-RAF PRMT5 molecular chaperones folding signalling signaling VER49009 VER 49009 cancers pyrazoles 4.866372007366
13132 VER-50589 Exclusive 747413-08-7 ≥98% ✓ 2010-04-06 4.802453959484 ver-50589 heat shock proteins Hsps Hsp90 cancers inhibitors inhibits inhibition Hsp27 Hsp72 C-RAF B-RAF survivin PRMT5 cells cylce arrest apoptosis tumors growth glioblastoma molecular chaperones protein folding signaling signalling pharma Isoxazoles 4.802453959484
11791 Vitamin D2 New 50-14-6 ≥98% 2012-05-24 148.659649122807 vitamin-d2 Infron; Uvesterol D; Davitamon D; Fortodyl; Mulsiferol; Calciferol; NSC 62792; Ergocalciferol; Radiostol buco-D condocaps condol crystallina D-arthin D-tracetten davitin De-rat concentrate decaps dee-osterol dee-ron dee-ronal deltalin deratol detalup diactol divit urto doral drisdol ercalciol geltabs hi-deratol ergorone ertron metadee mina D2 mykostin NSC62792 NSC-62792 oleovitamin D oleovitamin D2 osteil ostelin radsterin rodine C shock-ferol sterogyl vio D viosterol vitamin D2 vitavel-D 7489-18-1 8017-28-5 31316-19-5 bones cancers hypertension immunity yeast fungi invertebrates vitamins ergosterol ultraviolet radiation organisms 25-hydroxyvitamin 25-hydroxy vitamin 1,25-dihydroxyvitamin 1,25-dihyrdroxyvitamin 148.659649122807
11792 Vitamin D3 New 67-97-0 ≥98% 2012-05-24 149.379884182525 vitamin-d3 Arachitol; Delsterol; Quintox; Granuvit D3; Lutavit D; NSC 375571; Ricketon; Cholecalciferol; Trivitan calciol calcirol D3-vigantol decristol deparal devaron dry vitamin D3 100CWS/AM duphafral D3 1000 ekostop D3 FeraCol high-D 2X oleovit D3 oleovitamin D3 riken D3 oil 100 riken D3 oil 20 UVEDOSE Vi- De3 videkhol vigantoletten vigorsan vitinc dan-dee-3 8024-19-9 8050-67-7 bones hypertension cancers immunity dietary fish 7-dehydrocholesterol ultraviolet lights metabolized 25-hydroxyvitamin 25- hydroxy vitamins 1,25-dihydroxyvitamins 1,25-dihydroxy vitamins cytochrome P450 CYP450 isoforms livers retinoid X receptors genes expressions 149.379884182525
10944 WDR5 (human recombinant) - ≥95% 2011-08-05 14.152052839174 wdr5-human-recombinant BMP2-induced 3-kb Gene Protein; SWD3, Set1c WD40 repeat protein, homolog; WD-Repeat Protein 5; BIG3 epigenetics binding proteins methyltransferase MLL complex subunits 14.152052839174
11549 WDR9 bromodomain 2 (human recombinant) New - ≥85% 2012-03-01 15.723401238237 wdr9-bromodomain-2-human-recombinant WD repeat-containing protein 9; BRD and WD repeat-containing protein 1 genes expressions histones chromatin acetylation bromodomains epigenetics BET domain WD repeats Brg1 SMARCA4 15.723401238237
10010591 Wortmannin 19545-26-7 ≥98% 2008-11-21 30.065709170100 wortmannin KY 12420 phosphoinositide 3-kinase PI3K cells growth differentiations cancers motility inhibitors inhibits inhibition irreversible polo-like kinases PLK1 PLK3 mTOR DNA-PK DNAPK PL4K MLCK p38 MAPK 30.065709170100
13671 Wortmannin-Rapamycin Conjugate - ≥98% 2010-05-11 9.973338789986 wortmannin-rapamycin-conjugate phosphoinositides 3-kinases PI3K mammalian targets mTOR cancers inhibitors inhibits inhibition complex 1 mTORC1 tumors bevacizumab VEGF colons A498 HT29 53123-88-9 sirolimus prodrug linkers links 19545-26-7 KY 12420 renal phosphatidyl inositols 9.973338789986
10008883 WST-1 Cell Proliferation Assay Kit - 2006-09-07 75.640332189474 wst-1-cell-proliferation-assay-kit assays cells proliferation induction inhibitors inhibition inhibits growth factors signaling signalling molecules cycles regulatory factors cytokines mitogens drugs microtiter plates in vitro enzymes enzymatic cleavage tertrazolium salts formazan cellular mitochondrial dehydrogenases screen kits measures measurements cancers cell-based assay cell based assay cba 75.640332189474
10010199 WST-8 Cell Proliferation Assay Kit - 2007-09-11 75.212933875886 wst-8-cell-proliferation-assay-kit assays cells proliferation induction inhibitors inhibition inhibits growth factors signaling signalling molecules cycles regulatory factors cytokines mitogens drugs microwell plates in vitro enzymes enzymatic cleavage tertrazolium salts formazan cellular mitochondrial dehydrogenases screen kits measures measurements special:quarterly specialdiscount:50 specialstart:2007-12-01 specialend:2008-02-29 cell-based assay cell based assay cba 75.212933875886
13604 WYE-354 New 1062169-56-5 ≥98% 2012-01-12 12.173137712297 wye-354 mTOR mTORC1 mTORC2 inhibitors inhibits inhibition PI3K cancers cells growth PTENs tumors rapamycin complex 1 2 G1 phosphatidylinositol 3-kinase α PI3Kα kinases 12.173137712297
13639 WZ811 55778-02-4 ≥95% 2010-03-22 44.403024861878 wz811 CXC chemokines receptors CXCR4 stromal cell-derived factor-1 SDF-1 CXCL12 hematopoietic stem cells chemotaxis lymphocytes growth metastasis cancers T cells HIV infection inhibitors antagonist cAMP Matrigel invasion breast cancer adenocarcinoma inhibition alpha-Aminotoluene alpha Aminotoluene Phenylmethylamine Benzylamines 44.403024861878
10010895 Xanthine Oxidase Assay Kit - 2008-03-13 245.698376742962 xanthine-oxidase-assay-kit XO Assay Kit; Xanthine Oxidoreductase Assay Kit assays kits plasma serum tissues homogenates oxidoreductases molybdoflavoenzymes human purine catabolism catalyzing catalyzes hydroxylation hypoxanthine uric acids NADH superoxides reactive oxygen species ROS hydrogen peroxides H2O2 inschemia-reperfusion injury molecular cells death degeneration apoptosis mammalian livers intestines diseases horseradish HRP ADHP fluorescence fluorescent resorufin excitation emission wavelengths special:quarterly specialdiscount:50 specialstart:2007-03-01 specialend:2008-05-31 fluorometric 245.698376742962
13596 XAV939 284028-89-3 ≥98% 2009-12-03 20.314585635359 xav939 Wnt cancers β-catenin APC axin GSK3 poly-ADP-ribosylation tankyrases TNKS1 TNKS2 inhibitors inhibition inhibits 20.314585635359
10010200 XTT Cell Proliferation Assay Kit - 2007-09-11 54.557532260927 xtt-cell-proliferation-assay-kit assays cells proliferation induction inhibitors inhibition inhibits growth factors signaling signalling molecules cycles regulatory factors cytokines mitogens drugs microtiter plates in vitro enzymes enzymatic cleavage tertrazolium salts formazan cellular mitochondrial dehydrogenases screen kits measures measurements special:quarterly specialdiscount:50 specialstart:2007-12-01 specialend:2008-02-29 cell-based assay cell based assay cba 54.557532260927
11168 (−)-YK-4-279 New - ≥98% 2011-12-19 1.356353591160 -yk-4-279 ES-FLI1 oncogenes Ewing's sarcomas RNA helicases tumors cancers inhibitors apoptosis ETS transcription factors ERG ETV1 prostate fusion proteins diseases YK4279 YK 4279 growth xenografts cells chemotherapy resistant Ewings ESFLI1 ES FLI1 prostate 1.356353591160
11167 (+)-YK-4-279 New 1261038-93-0 ≥98% 2011-12-16 1.356353591160 -yk-4-279 ES-FLI1 oncogenes Ewing's sarcomas RNA helicases tumors cancers inhibitors apoptosis ETS transcription factors ERG ETV1 prostate YK4279 YK 4279 fusion proteins diseases growth orthotopic xenografts cells chemotherapy resistant Ewings EWS-FLI1 reduces in vitro in vivo family prostate cancers enantiomers EWSFLI1 EWS FLI1 1.356353591160
13661 YK-4-279 1037184-44-3 ≥98% 2010-02-05 2.712707182320 yk-4-279 ES-FLI1 oncogene Ewing's sarcomas RNA helicases A RHAs tumors cancers inhibitors apoptosis inhibition inhibited Ewings YK 4-279 YK4279 YK 4279 YK 4 279 Pentaacetic Acid, Diethylenetriamine Acid, Diethylenetriamine Pentaacetic Diethylenetriamine Pentaacetic Acid calcium trisodium pentetate Pentetic Acid DTPA pentacin penthanil 2.712707182320
10975 Zebularine 3690-10-6 ≥98% 2011-08-23 10.892338121546 zebularine DNMTs inhibitors DNA methyltransferases cancers cells analogs cytidines methylation carcinomaTK6 jurkat KG-1 HCT116 10.892338121546
71800 (Z)-Guggulsterone 39025-23-5 ≥98% 2009-12-01 1.169042357274 -z-guggulsterone anti flammatory cancers FXR bile acids LDL cholesterol tumors IL-6 STAT3 VEGF Akt 1.169042357274
10010367 ZM 336372 208260-29-1 >98% 2008-01-09 3.659251632345 zm-336372 Raf-1 c-raf inhibitors inhibition inhibits cancers anti-cancer MEK 1/2 MAPK signals transductions proliferations cells cycles ERK1 ERK2 ERK1/2 ATP adenosine triphosphate signaling carcinoid tumor 3.659251632345
13601 ZM 447439 331771-20-1 2010-08-03 7.050110497237 zm-447439 auroras A B C kinases mitosis cytokinesis centromere inhibitors inhibits inhibition cancers Benzamides 7.050110497237
300013 β-Catenin Blocking Peptide - 3.408707182320 -catenin-blocking-peptide b-catenin beta-catenin immunoanalysis western blots immunoblotting controls peptides cancer cell .beta.-catenin wb 3.408707182320
100029 β-Catenin Polyclonal Antibody - 6.437790055248 -catenin-polyclonal-antibody antibodies antisera antiserum western blots blotting wb icc immunocytochemistry b-catenin cancers cell immunoblotting IHC immunohistochemistry 6.437790055248
10009137 β-Gal-NONOate 357192-77-9 ≥98% 2007-11-10 31.660946132596 -gal-nonoate nitric oxides NOs donors anti-cancer anticancers .beta.-galatosidases cytoxic bactericidal cell-lines genes cytotoxicity 31.660946132596
10010621 γ-CEHC EIA Kit (plasma and serum) - 2008-03-21 26.213447513812 -cehc-eia-kit-plasma-and-serum 2,7,8-trimethyl-2-(β-Carboxy-Ethyl)-6-Hydroxychroman EIA Kit solid plates competitive quantification kits eias enzymes immunoassays gammaCEHC gCEHC gamma-CEHC g-CEHC tocopherol tocotrienols vitamins E g-tocopherols .gamma.-tocopherol gamma-tocopherol lipid soluble antioxidants diets metabolites livers cytochrome p450 CYP450 natriuretic acitvity nitric oxides NO radicals inhibits inhibitions inhibitors COX cyclooxygenases macrophages epithelial cells plasma serums blood cardiovascular diseases prostate cancers assays 26.213447513812
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