| 50511 |
11(12)-EET
|
|
123931-40-8 |
≥95%
|
|
|
|
81.823216015278
|
11-12-eet
|
11(12)-EpETrE
|
epoxides epoxygenases 11,12-EETs cytochrome P450 (+/-)11,12-EpETrEs (+/-)11(12)-EpETrEs |
81.823216015278
|
| 10008598 |
11(12)-EET Ethanolamide
|
|
- |
≥98%
|
|
|
2007-01-16
|
26.410596685083
|
11-12-eet-ethanolamide
|
11(12)-EpETrE Ethanolamide
|
AEA endocannabinoids Arachidonoyl ethanolamides CYP450 cytochromes metabolism neurochemistry anxiety depression 14,15-EET 14,15-EpETrE 14,15-EET-EA 14,15-EET-ethanolamide 14,15-epetre-ea 14,15-ethanolamide anandamides lipids neurotransmitters cannabinergic cannabinoids CBs FAAH inhibitor fatty acids hydrolases cbs synthetic |
26.410596685083
|
| 10007262 |
11(12)-EET Lipid Maps MS Standard
|
|
- |
≥98%
|
|
|
2009-02-11
|
25.812527624309
|
11-12-eet-lipid-maps-ms-standard
|
11(12)-EpETrE
|
epoxides epoxygenases 11,12-EETs cytochrome P450 (+/-)11,12-EpETrEs (+/-)11(12)-EpETrEs MS mass spectrometry standards |
25.812527624309
|
| 10462 |
11(12)-EpETE
Exclusive
|
|
504435-15-8 |
≥98%
|
|
✓ |
2010-10-28
|
6.426522176380
|
11-12-epete
|
11,12-EEQ; 11,12-Epoxyeicosatetraenoic Acid
|
eicosapentaenoic acids EPAs epoxyeicosatetraenoic EpETE EETeTr cytochromes P450 epoxygenases CYP450 10-[3-2Z,5Z-octadien-1-yl-2-oxiranyl]-5Z,8Z-decadienoic acid 11,12-epoxyeicosatrienoic acid |
6.426522176380
|
| 10008647 |
11α-hydroxy Testosterone
|
|
3066-12-4 |
>97%
|
|
|
2006-05-11
|
2.146961325967
|
11-hydroxy-testosterone
|
|
spi-bio spibio metabolites metabolism CYP450 CYP-450-3A CYP-3A CYP3A cytochromes M02007 endocrinology 11-hydroxytestosterone |
2.146961325967
|
| 10009832 |
(±)12,13-DiHOME
|
|
263399-35-5 |
≥98%
|
|
|
2007-06-26
|
4.069465930018
|
-12-13-dihome
|
Isoleukotoxin diol
|
epoxides epoxygenase leukotoxin cytochrome P450 CYP450 sEH soluble epoxide hydrolase UGT glucuronidation UGT2B7 |
4.069465930018
|
| 10009994 |
(±)12,13-DiHOME-d4
|
|
- |
≥99% deuterated forms (d1-d4)
|
|
|
2007-06-26
|
4.188692449355
|
-12-13-dihome-d4
|
Isoleukotoxin diol-d4
|
epoxides epoxygenase leukotoxin cytochrome P450 CYP450 sEH soluble epoxide hydrolase UGT glucuronidation UGT2B7 mass spectrometry MS deuterated deuterium |
4.188692449355
|
| 34560 |
12(R)-HETE
|
|
82337-46-0 |
≥98%
|
|
|
|
37.568213627992
|
12-r-hete
|
|
hydroxy acids 12-LOs sea urchin 12R-HETEs 12-HETEs fatty 12(R)-HETEs 12(R)HETEs 12-lipoxygenases |
37.568213627992
|
| 10007247 |
12(R)-HETE Lipid Maps MS Standard
|
|
82337-46-0 |
≥98%
|
|
|
2009-02-17
|
21.069848066298
|
12-r-hete-lipid-maps-ms-standard
|
|
hydroxy acids 12-LOs sea urchin 12R-HETEs 12-HETEs fatty 12(R)-HETEs 12(R)HETEs 12-lipoxygenases MS mass spectrometry standards |
21.069848066298
|
| 31570 |
12(S)-hydroxy-16-Heptadecynoic Acid
Exclusive
|
|
148019-74-3 |
≥98%
|
|
✓ |
|
0.356243093923
|
12-s-hydroxy-16-heptadecynoic-acid
|
|
acetylene inhibitors omega-hydroxylases cytochromes P450 hydroxy fatty acids .omega.-hydroxyases w-hydroxylases inhibits 12S-hydroxy-16-heptadecynoic |
0.356243093923
|
| 10006998 |
(±)14,15-DiHETE
Exclusive
|
|
- |
≥98%
|
|
✓ |
2005-07-13
|
12.106672805402
|
-14-15-dihete
|
(±)14,15-dihydroxy-eicosa-5,8,11,17-Tetraenoic Acid
|
epoxygenases metabolites EPA eicosapentaenoic acids epoxidations hydroxylations w-3 .omega.-3 fatty acids marine organisms incubated rats livers microsomes colitis homogenates cytochromes P450-catlyzed epoxidations w-6 .omega.-6 double bonds conversion vicinal diols epoxides hydrolases excreted excretion humans ingesting fish oils supplements 14,15-dihete |
12.106672805402
|
| 50651 |
14(15)-EET
|
|
- |
≥98%
|
|
|
|
80.729838718678
|
14-15-eet
|
14(15)-EpETrE
|
epoxides epoxygenases 14,15-EETs cytochrome P450 (+/-)14,15-EpETrEs (+/-)14(15)-EpETrEs |
80.729838718678
|
| 10006410 |
14(15)-EET-d11
|
|
- |
≥99% deuterated forms (d1-d11)
|
|
|
2007-07-22
|
91.322375690608
|
14-15-eet-d11
|
14(15)-EpETrE-d11
|
epoxides epoxygenases cytochrome P450 (+/-)14(15)-EpETrEs (+/-)5,6-EpETrEs fatty acids deuterated deuterium CYP450 mass spectrometry MS 14,15-EETs biosynthesized liver microsomes pregnancy hypertension |
91.322375690608
|
| 10008599 |
14(15)-EET Ethanolamide
|
|
- |
≥95%
|
|
|
2006-08-07
|
22.645801104972
|
14-15-eet-ethanolamide
|
14(15)-EpETrE Ethanolamide; 14(15)-Epoxy Eicosatrienoyl Ethanolamide
|
CYP450 cytochrome P450 metabolites AEA arachidonoyl ethanolamides anandamide lipids neurotransmitter cannibinergic cannabinoid CB1 CB2 receptors enzymatic metabolism FAAH fatty acid amide hydrolases endocannabinoid neurochemistry anxiety depression neuroscience 14,15-EET 14,15-EpETrE 14,15-EET-EA 14,15-EET-ethanolamide 14,15-epetre-ea 14,15-ethanolamide cbs synthetic cannabinoids |
22.645801104972
|
| 10007263 |
14(15)-EET Lipid Maps MS Standard
|
|
- |
≥98%
|
|
|
2009-02-11
|
17.208238182934
|
14-15-eet-lipid-maps-ms-standard
|
14(15)-EpETrE
|
epoxides epoxygenases 14,15-EETs cytochrome P450 (+/-)14,15-EpETrEs (+/-)14(15)-EpETrEs MS mass spectrometry standards |
17.208238182934
|
| 10007527 |
14(15)-EpEDE
Exclusive New
|
|
351533-80-7 |
≥98%
|
|
✓ |
2012-03-09
|
51.217386433394
|
14-15-epede
|
14,15-Epoxyeicosadienoic Acid
|
epoxides epoxygenases DGLA dihomo- γ-linolenic acids eicosatrienoic ETA cytochromes P450 PUFA monoepoxides 14,15-EpEDE 14,15-EpED-8,11 gamma-linolenic g-linolenic .gamma.-linolenic epoxyeicosadienoic |
51.217386433394
|
| 10173 |
14(15)-EpETE
|
|
131339-24-7 |
≥90%
|
|
|
2004-01-14
|
29.782071823204
|
14-15-epete
|
14,15-epoxy Eicosatetraenoic Acid; 14,15 EEQ
|
epoxides epoxygenases cytochrome P450 (±)14,15-EpETEs (+/-)14,15-EpETEs fatty acids (+/-)14(15)EpETrEs 14(15)EETs eicosatrienoic 14,15-EEQ 14,15EEQ |
29.782071823204
|
| 10174 |
16(17)-EpDPE
|
|
- |
≥90%
|
|
|
2004-01-14
|
34.388830570902
|
16-17-epdpe
|
16,17-epoxy Docosapentaenoic Acid; 16,17 EDP
|
epoxides epoxygenases cytochrome P450 (±)16,17-EpDPEs (+/-)16,17-EpDPEs fatty acids (+/-)16(17)EpDPEs 16(17)EETs eicosatrienoic neurochemistry 16,17-EDP 16,17EDP |
34.388830570902
|
| 10010635 |
(±)16-HETE
|
|
128914-46-5 |
≥98%
|
|
|
2008-06-09
|
30.316611418048
|
-16-hete
|
|
CYP450 eicosanoid metabolism kidneys ATPase ion transport vasodilation renal hypertension |
30.316611418048
|
| 10004385 |
16(R)-HETE
|
|
183509-22-0 |
≥98%
|
|
|
2008-07-28
|
1.431491712707
|
16-r-hete
|
|
CYP450 eicosanoid metabolism kidney ion transport vasodilation renal hypertension HETEs |
1.431491712707
|
| 10004384 |
16(S)-HETE
|
|
183509-23-1 |
≥98%
|
|
|
2008-07-23
|
1.556077348066
|
16-s-hete
|
|
inhibitors inhibits inhibitions CYP450 eicosanoid metabolism kidneys ATPase ion transport renal hypertension HETEs 16SHETE 16S-HETE 16 S HETE |
1.556077348066
|
| 10006999 |
(±)17,18-DiHETE
Exclusive
|
|
- |
≥98%
|
|
✓ |
2005-07-13
|
9.208910812943
|
-17-18-dihete
|
(±)17,18-dihydroxy-eicosa-5,8,11,14-Tetraenoic Acid
|
EPAs eicosapentaenoic acids epoxidations hydroxylations epoxygenases metabolites w-3 .omega.-3 fatty marine organisms metabolites produced incubated rat tissues homogenates cynomolgus monkey seminal vesicles cytochrome P450-catalyzed double bond conversion vicinal diols epoxides hydrolases metabolized Gaeumannomyces graminis 116477-53-3 |
9.208910812943
|
| 50861 |
17(18)-EpETE
|
|
- |
≥90%
|
|
|
2004-01-14
|
30.898830570902
|
17-18-epete
|
17,18-epoxy Eicosatetraenoic Acid; 17,18 EEQ
|
epoxides epoxygenases cytochromes P450 (±)17,18-EpETEs (+/-)17,18-EpETEs fatty acids (+/-)17(18)EpETrEs 17(18) CYP450 CYP-450 epoxidation docosahexaenoic acids EETs eicosatrienoic EPA DHA 17,18-EEQ 17,18EEQ |
30.898830570902
|
| 10010636 |
(±)17-HETE
|
|
128914-47-6 |
≥98%
|
|
|
2008-06-11
|
2.432523020257
|
-17-hete
|
|
CYP450 eicosanoid metabolism kidneys ATPase ion transport renal hypertension inhibitors inhibits inhibition |
2.432523020257
|
| 90270 |
17-Octadecynoic Acid
|
|
34450-18-5 |
>98%
|
|
|
|
24.856519337017
|
17-octadecynoic-acid
|
ODYA; 17-ODA
|
acetylene omega-hydroxylase .omega.-hydroxylase w-hydroxylase inhibitors cytochrome P450 fatty acids analogs 20-hydroxylasae 17-oda 17-odya |
24.856519337017
|
| 10010637 |
17(R)-HETE
|
|
183509-24-2 |
≥98%
|
|
|
2008-08-18
|
13.202904498816
|
17-r-hete
|
|
CYP450 Eicosanoid metabolism kidney ATPase ion transport renal hypertension isomers HETEs |
13.202904498816
|
| 10011305 |
17(S)-HETE
|
|
183509-25-3 |
≥98%
|
|
|
2008-08-25
|
13.771176006313
|
17-s-hete
|
|
CYP450 Eicosanoid metabolism kidney ATPase ion transport renal hypertension |
13.771176006313
|
| 10010638 |
(±)18-HETE
|
|
133268-58-3 |
≥97%
|
|
|
2008-06-13
|
2.947248618784
|
-18-hete
|
|
CYP450 eicosanoid metabolism kidney vasodilation CYP2E1 20-HETE 20HETE 18HETE renal hypertension |
2.947248618784
|
| 10007001 |
(±)19,20-DiHDPA
|
|
- |
≥98%
|
|
|
2005-09-15
|
27.311981057616
|
-19-20-dihdpa
|
(±)19,20-DiHDoPE
|
epoxygenases metabolites DHA docosahexaenoic acids fatty w-3 omega-3 .omega.-3 neural tissues retina brain incubated incubation NADPH-supplemented nicotinamide adenine dinucleotide phosphates rat livers microsomes metabolized metabolizing monkey seminal vesicles cytochromes P450-catalyzed CYP450 epoxidation double bond vicinal diols epoxide hydrolases hydroxylation 138705-17-6 |
27.311981057616
|
| 10175 |
19(20)-EpDPE
|
|
- |
≥98%
|
|
|
2004-01-14
|
40.950773480663
|
19-20-epdpe
|
19,20-epoxy Docosapentaenoic Acid; 19,20 EDP
|
metabolites epoxides epoxygenases cytochrome P450 (±)19,20-EpDPEs (+/-)19,20-EpDPEs fatty acids (+/-)19(20)EpDPEs 19(20)EETs eicosatetraenoic 19,20-EETs neurochemistry 19,20-EDP 19,20EDP |
40.950773480663
|
| 10385 |
1'-Hydroxymidazolam
|
|
59468-90-5 |
≥95%
|
|
|
2010-04-21
|
16.977900552486
|
1-hydroxymidazolam
|
Ro 21-6347
|
79683-62-8 81877-60-3 138614-39-8 SPIBIO SPI Bio α-Hydroxymidazolam CYP3A CYP 3A benzodiazepine derivatives metabolism |
16.977900552486
|
| 10386 |
1'-Hydroxymidazolam β-D-Glucuronide
|
|
81256-81-7 |
≥98%
|
|
|
2010-04-22
|
16.977900552486
|
1-hydroxymidazolam-d-glucuronide
|
|
SPIBIO SPI Bio oxidative metabolism midazolam derivatives CYP3A CYP 3A benzodiazepine |
16.977900552486
|
| 90030 |
20-HETE
|
|
79551-86-3 |
≥98%
|
|
|
|
90.404548802946
|
20-hete
|
20-hydroxy Arachidonic Acid
|
hydroxy fatty acids omega-oxidation .omega.-oxidation w-oxidation cytochrome P450 CYP450 arachidonic HETEs metabolites P-450 vasoconstrictors vasoconstriction |
90.404548802946
|
| 390030 |
20-HETE-d6
|
|
- |
≥99% deuterated forms (d1-d6)
|
|
|
|
94.095276243094
|
20-hete-d6
|
20-hydroxy Arachidonic Acid-d6
|
CYP450 vasocontriction standards vasoconstrictors GC-MS GC/MS LC-MS LC/MS cytochrome chromatography mass spectroscopy deuterium deuterateds |
94.095276243094
|
| 10008602 |
20-HETE Ethanolamide
|
|
- |
≥98%
|
|
|
2006-09-26
|
42.358876611418
|
20-hete-ethanolamide
|
20-hydroxy AEA; 20-hydroxy Arachidonoyl Ethanolamide
|
hydroxy fatty acids omega-oxidation .omega.-oxidation w-oxidation cytochrome P450 CYP450 arachidonic HETEs metabolites P-450 vasoconstrictors vasoconstriction ethanolamides cannabinoids cbs synthetic |
42.358876611418
|
| 10007269 |
20-HETE Lipid Maps MS Standard
|
|
79551-86-3 |
≥98%
|
|
|
2009-02-18
|
22.238900552486
|
20-hete-lipid-maps-ms-standard
|
20-hydroxy Arachidonic Acid
|
hydroxy fatty acids omega-oxidation .omega.-oxidation w-oxidation cytochrome P450 CYP450 arachidonic HETEs metabolites P-450 vasoconstrictors vasoconstriction MS mass spectrometry standards |
22.238900552486
|
| 10009962 |
2-(14,15-Epoxyeicosatrienoyl) Glycerol
|
|
848667-56-1 |
≥95%
|
|
|
2008-04-03
|
39.494825046040
|
2-14-15-epoxyeicosatrienoyl-glycerol
|
2-14,15-EG
|
2-AG CYP450 metabolism mitogens cancers kidneys endocannabinoids cannabinoids cbs synthetic |
39.494825046040
|
| 10011048 |
2,3-dihydrothieno-Thiadiazole Carboxylate
|
|
- |
≥98%
|
|
|
2008-12-14
|
0.224677716390
|
2-3-dihydrothieno-thiadiazole-carboxylate
|
MTCC
|
inhibitors inhibits inhibition CYP450 thiadiazoles cytochromes |
0.224677716390
|
| 10011040 |
4,5-diphenyl-1,2,3-Thiadiazole
|
|
5393-99-7 |
≥98%
|
|
|
2008-11-15
|
0.674033149171
|
4-5-diphenyl-1-2-3-thiadiazole
|
NSC 2505
|
thiadiazoles inhibitors inhibits inhibition CYP450 4,5-diphenylthiazole enzymes cytochrome |
0.674033149171
|
| 90314 |
4(5)-EpDPE methyl ester
|
|
121818-29-9 |
≥98%
|
|
|
|
28.196648250460
|
4-5-epdpe-methyl-ester
|
4,5-epoxy Docosapentaenoic Acid methyl ester; 4,5-EDP methyl ester
|
cytochrome P450 metabolites epoxide epoxygenase neurochemistry |
28.196648250460
|
| 10008518 |
4-hydroxy Diclofenac
|
|
64118-84-9 |
≥97%
|
|
|
2006-05-11
|
59.256132596685
|
4-hydroxy-diclofenac
|
|
spi-bio spibio metabolites metabolism CYP450 CYP-450-2C9 CYP-2C9 CYP2C9 cytochromes M02004 |
59.256132596685
|
| 10008520 |
4-hydroxy Tolbutamide
|
|
5719-85-7 |
>97%
|
|
|
2006-05-11
|
34.913591160220
|
4-hydroxy-tolbutamide
|
|
spi-bio spibio metabolites metabolism CYP450 CYP-450-2C9 CYP-2C9 CYP2C9 cytochromes M02009 |
34.913591160220
|
| 10011049 |
4-phenyl-5-methyl-1,2,3-Thiadiazole
|
|
64273-28-5 |
≥98%
|
|
|
2009-03-14
|
0.337016574585
|
4-phenyl-5-methyl-1-2-3-thiadiazole
|
NSC 358739
|
cytochrome P450 CYP450 CYP2B4 CYP2E1 CYP1A2 inhibitors inhibits inhibition thiadiazoles fungicide herbicide plant growth regulator |
0.337016574585
|
| 50211 |
5(6)-EET
|
|
- |
≥98%
|
|
|
|
14.538713496448
|
5-6-eet
|
5(6)-EpETrE
|
epoxides epoxygenases cytochrome P450 (+/-)5(6)-EpETrEs (+/-)5,6-EpETrEs 5,6-EETs fatty acids |
14.538713496448
|
| 10009984 |
5(6)-EET-d11
|
|
- |
≥99% deuterated forms (d1-d11)
|
|
|
2007-06-06
|
15.434309392266
|
5-6-eet-d11
|
5(6)-EpETrE-d11
|
epoxides epoxygenases cytochrome P450 (+/-)5(6)-EpETrEs (+/-)5,6-EpETrEs 5,6-EETs fatty acids deuterated deuterium |
15.434309392266
|
| 10008596 |
5(6)-EET Ethanolamide
|
|
- |
≥95%
|
|
|
2006-10-20
|
9.080923441200
|
5-6-eet-ethanolamide
|
5(6)-EpETrE Ethanolamide
|
epoxides epoxygenases 5,6-EETs cytochrome P450 (+/-)5(6)-EpETrEs (+/-)5,6-EpETrEs fatty acids esters ethanolamides metabolites AEA anandamides arachidonoyl neurotransmitters cannabinergic endocannabinoids CB1 CB2 receptors central peripheral FAAH hydrolases metabolism lipoxygenases inhibition (±)5(6)-Epoxy eicosatrienoyl 14,15-EET 14,15-EpETrE 14,15-EET-EA 14,15-EET-ethanolamide 14,15-epetre-ea 14,15-ethanolamide cannabinoids cbs synthetic |
9.080923441200
|
| 10007260 |
5(6)-EET Lipid Maps MS Standard
|
|
- |
≥98%
|
|
|
2009-02-05
|
6.893591160221
|
5-6-eet-lipid-maps-ms-standard
|
5(6)-EpETrE
|
epoxides epoxygenases cytochrome P450 (+/-)5(6)-EpETrEs (+/-)5,6-EpETrEs 5,6-EETs fatty acids MS mass spectrometry standards |
6.893591160221
|
| 10009598 |
6,7-dihydroxy Bergamottin
|
|
145414-76-2 |
≥98%
|
|
|
2007-07-24
|
4.857292817679
|
6-7-dihydroxy-bergamottin
|
6,7-DHB
|
cytochrome P450 CYP3a4 inhibitors inhibits inhibition grapefruit juice testosterone ingestion drugs metabolized metabolite metabolism stereochemistry endocrinology |
4.857292817679
|
| 10009029 |
6-hydroxy Chlorzoxazone
|
|
1750-45-4 |
≥97%
|
|
|
2006-07-12
|
1.856353591160
|
6-hydroxy-chlorzoxazone
|
NSC 24955
|
SPI-BIO SPIBIO substrates CYP2C8 CYP-2C8 CYP 2C8 cytochromes metabolites M02003 |
1.856353591160
|
| 19027 |
6α-hydroxy Paclitaxel
|
|
153212-75-0 |
≥97%
|
|
|
2009-09-23
|
38.679214241866
|
6-hydroxy-paclitaxel
|
|
10009027 substrates CYP450 CYP-450-2E1 CYP-2E1 CYP2E1 cytochromes metabolites M02006 |
38.679214241866
|
| 10008519 |
6β-hydroxy Testosterone
|
|
62-99-7 |
≥97%
|
|
|
2006-05-11
|
2.146961325967
|
6-hydroxy-testosterone
|
4-Androsten-6β,17β-diol-3-one; 6β, 17β,-Dihydroxyandrost-4-en-3-one
|
metabolites metabolism CYP450 CYP-450-3A CYP-3A CYP3A cytochromes M02008 endocrinology CYP3A4 CYP3A5 P450 glucocorticoids xenobiotics steroids hormones testosterone |
2.146961325967
|
| 50351 |
8(9)-EET
|
|
- |
≥98%
|
|
|
|
16.566364640884
|
8-9-eet
|
8(9)-EpETrE
|
epoxides epoxygenases cytochrome P450 (±)8,9-EpETrEs (+/-)8,9-EpETrEs fatty acids (+/-)8(9)EpETrEs 8(9)EETs eicosatrienoic 8,9-EETs |
16.566364640884
|
| 10007261 |
8(9)-EET Lipid Maps MS Standard
|
|
- |
≥98%
|
|
|
2009-02-10
|
7.764331491712
|
8-9-eet-lipid-maps-ms-standard
|
8(9)-EpETrE
|
epoxides epoxygenases cytochrome P450 (±)8,9-EpETrEs (+/-)8,9-EpETrEs fatty acids (+/-)8(9)EpETrEs 8(9)EETs eicosatrienoic 8,9-EETs MS mass spectrometry standards |
7.764331491712
|
| 10010569 |
Acenocoumarol
|
|
152-72-7 |
≥98%
|
|
|
2008-07-25
|
1.159602209944
|
acenocoumarol
|
Sinthrome®; G-23350; Nicoumalone; Acenocoumarin; Sintrom®
|
CYP450 thrombosis vitamin K warfarin bleeding blood coagulation inhibitors inhibits inhibition |
1.159602209944
|
| 10006400 |
CAY10462
|
|
502656-68-0 |
>98%
|
|
|
2005-01-19
|
30.100883977900
|
cay10462
|
|
hydroxy eicosatetraenoic acids 20-HETEs CYP450 cytochromes renal kidney metabolites arachidonic enzymes CYP4A inhibits inhibitors inhibition metabolism CAY10434 dihydrochlorides selective selectivity synthases |
30.100883977900
|
| 600670 |
CYP1A1/2 Induction STEP Reporter Assay Kit (Luminescence)
Exclusive New
|
|
- |
|
|
✓ |
2012-05-23
|
98.725686222924
|
cyp1a1-2-induction-step-reporter-assay-kit-luminescence
|
|
kits assays measures measurements cytochromes P450s CYP450 CYPs heme-thiolates monoxygenases metabolizes endogenous compounds xenobiotics pollutants environmentals drugs enzymes metabolisms medications induction pharmacokinetics drug-drug interactions co-administered therapeutics CYP1A2 CYP2C19 CYP2C9 CYP2D6 CYP3A4 CYP1A1 CYP1A2 detoxification metabolic polycyclic aromatic hydrocarbons cigarette smoke combustion arylamines heterocyclic amines char-broiled meats intermediates mutagenics carcinogenics inhibits toxicity low efficacy development primary humans hepatocytes livers cells tissues hepatocyte-like CBAs cell-based assays kits measures measurements cultured lines transfected genes promoter/enhancer sequences high-throughput assessments Surface transfection Expression protocols solid phases transient originus, Inc. incorporated University of Michigan U M US patents USPT 6897067 6902933 7056741 complexes DNA deoxyribonucleases proteins adherent endocytosis solution-phase plasmids secreted alkaline phosphatases SEAP inducer-activated transcription factors TFs signals signaling culture mediums luminescence-based 3-MC 3MC |
98.725686222924
|
| 173125 |
CYP1A (cod) Monoclonal Antibody (NP-7)
|
|
- |
|
|
|
|
1.412523020257
|
cyp1a-cod-monoclonal-antibody-np-7
|
Cytochrome P450 1A (Cod); C02406101
|
antibodies cyp-1a p-450 EIAs enzyme immunoassays elisas immunoblotting immunohistochemistry IHC antisera antiserum biosense Biosense Enzyme-linked immunosorbent assays |
1.412523020257
|
| 173132 |
CYP1A (fish) Monoclonal Antibody (C10-7)
|
|
- |
|
|
|
|
7.549511262218
|
cyp1a-fish-monoclonal-antibody-c10-7
|
Cytochrome P450 1A (fish)
|
rainbow trout antibodies cyp-1a p-450 EIAs enzyme immunoassays elisas western blots blotting WB antisera antiserum biosense Biosense Enzyme-linked immunosorbent assays immunoblotting |
7.549511262218
|
| 173135 |
CYP1A (fish) Polyclonal Antibody (CP-226)
|
|
- |
|
|
|
|
1.412523020257
|
cyp1a-fish-polyclonal-antibody-cp-226
|
Cytochrome P450 1A (fish)
|
biosense vitellogenins antibodies antibody ELISAs EIAs enzyme immunoassays western blots blotting WB antisera antiserum Biosense Enzyme-linked immunosorbent assays immunoblotting |
1.412523020257
|
| 10009040 |
Cytochrome b5 (human)
|
|
- |
|
|
|
2006-07-13
|
0.675260896255
|
cytochrome-b5-human
|
|
CYPb5 cytochromes CYP enzymes M11001 spi-bio spibio |
0.675260896255
|
| 10143 |
Cytochrome P450 1A1 (human) Yeast Reductase
|
|
- |
|
|
|
|
0.675260896255
|
cytochrome-p450-1a1-human-yeast-reductase
|
CYP1A1 YR
|
CYP4501A1-YR cytochromes CYP-reductases enzymes M40003 spi-bio spibio |
0.675260896255
|
| 10144 |
Cytochrome P450 1A2 (human) Yeast Reductase
|
|
- |
|
|
|
|
0.675260896255
|
cytochrome-p450-1a2-human-yeast-reductase
|
CYP1A2 YR
|
CYP4501A2-YR cytochromes CYP-reductases enzymes M40004 spi-bio spibio |
0.675260896255
|
| 10148 |
Cytochrome P450 1B1 (human) Yeast Reductase
|
|
- |
|
|
|
|
0.675260896255
|
cytochrome-p450-1b1-human-yeast-reductase
|
CYP1B1 YR
|
CYP4501B1-YR cytochromes CYP-reductases enzymes M40005 spi-bio spibio |
0.675260896255
|
| 10145 |
Cytochrome P450 2A6 (human) Yeast Reductase
|
|
- |
|
|
|
|
0.675260896255
|
cytochrome-p450-2a6-human-yeast-reductase
|
CYP2A6 YR
|
CYP4502A6-YR cytochromes CYP-reductases enzymes M40006 spi-bio spibio |
0.675260896255
|
| 10149 |
Cytochrome P450 2B6 (human) Human Reductase
|
|
- |
|
|
|
|
0.675260896255
|
cytochrome-p450-2b6-human-human-reductase
|
CYP2B6 HR
|
CYP4502B6-HR cytochromes CYP-reductases enzymes M41007 spi-bio spibio |
0.675260896255
|
| 10009041 |
Cytochrome P450 2B6 (human) Human Reductase with Cytochrome b5
|
|
- |
|
|
|
2006-07-11
|
0.675260896255
|
cytochrome-p450-2b6-human-human-reductase-with-cytochrome-b5
|
CYP2B6 HR with Cytochrome b5
|
CYP4502B6-HR cytochromes CYP-reductases enzymes M41107 spi-bio spibio |
0.675260896255
|
| 10009044 |
Cytochrome P450 2B6 (human) Yeast Reductase
|
|
- |
|
|
|
2006-07-11
|
0.675260896255
|
cytochrome-p450-2b6-human-yeast-reductase
|
CYP2B6 YR
|
CYP4502B6-YR cytochromes CYP-reductases enzymes M40007 spi-bio spibio |
0.675260896255
|
| 10152 |
Cytochrome P450 2C18 (human) Yeast Reductase
|
|
- |
|
|
|
|
0.675260896255
|
cytochrome-p450-2c18-human-yeast-reductase
|
CYP2C18 YR
|
CYP4502C18-YR cytochromes CYP-reductases enzymes M40010 spi-bio spibio |
0.675260896255
|
| 10150 |
Cytochrome P450 2C8 (human) Yeast Reductase
|
|
- |
|
|
|
|
0.675260896255
|
cytochrome-p450-2c8-human-yeast-reductase
|
CYP2C8 YR
|
CYP4502C8-YR cytochromes CYP-reductases enzymes M40008 |
0.675260896255
|
| 10151 |
Cytochrome P450 2C9 (human) Yeast Reductase
|
|
- |
|
|
|
|
6.717618170657
|
cytochrome-p450-2c9-human-yeast-reductase
|
CYP2C9 YR
|
CYP4502C9-YR cytochromes CYP-reductases enzymes M40009 spi-bio spibio |
6.717618170657
|
| 10153 |
Cytochrome P450 2D6 (human) Yeast Reductase
|
|
- |
|
|
|
|
0.675260896255
|
cytochrome-p450-2d6-human-yeast-reductase
|
CYP2D6 YR
|
CYP4502D6-YR cytochromes CYP-reductases enzymes M40011 spi-bio spibio |
0.675260896255
|
| 10154 |
Cytochrome P450 2E1 (human) Yeast Reductase
|
|
- |
|
|
|
|
0.675260896255
|
cytochrome-p450-2e1-human-yeast-reductase
|
CYP2E1 YR
|
CYP4502E1-YR cytochromes CYP-reductases enzymes M40012 spi-bio spibio |
0.675260896255
|
| 10146 |
Cytochrome P450 3A4 (human) Human Reductase
|
|
- |
|
|
|
|
3.869273044489
|
cytochrome-p450-3a4-human-human-reductase
|
CYP3A4 HR
|
CYP4503A4-HR cytochromes CYP-reductases enzymes M41013 spi-bio spibio |
3.869273044489
|
| 10009042 |
Cytochrome P450 3A4 (human) Human Reductase with Cytochrome b5
|
|
- |
|
|
|
2006-07-11
|
2.461305612096
|
cytochrome-p450-3a4-human-human-reductase-with-cytochrome-b5
|
CYP3A4 HR with Cytochrome b5
|
CYP4503A4-HR cytochromes CYP-reductases enzymes M41113 spi-bio spibio |
2.461305612096
|
| 10147 |
Cytochrome P450 3A5 (human)
|
|
- |
|
|
|
|
0.675260896255
|
cytochrome-p450-3a5-human
|
CYP3A5 HR
|
CYP4503A5-HR cytochromes CYP-reductases enzymes M41014 spi-bio spibio |
0.675260896255
|
| 10009043 |
Cytochrome P450 3A5 (human) Human Reductase with Cytochrome b5
|
|
- |
|
|
|
2006-07-11
|
0.675260896255
|
cytochrome-p450-3a5-human-human-reductase-with-cytochrome-b5
|
CYP3A5 HR with Cytochrome b5
|
CYP4503A5-HR cytochromes CYP-reductases enzymes M41114 spi-bio spibio |
0.675260896255
|
| 10005199 |
Cytochrome P450 Control Human Reductase
|
|
- |
|
|
|
2004-05-17
|
1.473603437691
|
cytochrome-p450-control-human-reductase
|
|
CYP4501A1-YR cytochromes CYP-reductases enzymes M41002 spi-bio spibio |
1.473603437691
|
| 10005198 |
Cytochrome P450 Control Yeast Reductase
|
|
- |
|
|
|
2004-05-17
|
0.675260896255
|
cytochrome-p450-control-yeast-reductase
|
|
CYP4501A1-YR cytochromes CYP-reductases enzymes M40002 spi-bio spibio |
0.675260896255
|
| 10018 |
DDMS
|
|
206052-03-1 |
>98%
|
|
|
2005-02-22
|
9.518784530387
|
ddms
|
Dibromo-dodecenyl-methylsulfimide
|
20-HETEs inhibits inhibitors inhibition synthesis CYP450-4A2 renal hypotension vascular homeostasis circulation kidneys vasodilation vasodilators NONOates CYP4A2 donors cytochrome |
9.518784530387
|
| 10111 |
EA4
|
|
- |
≥95%
|
|
|
2005-10-12
|
11.138498242089
|
ea4
|
|
phospholipase A2 cPLA2 RBCs red blood cells CYP1A1 CYP1B1 cytochromes P450 cytosolic cow bovine human group IV quinones derivatives inhibits inhibition rPLA2 ionophore-induced ionophores arachidonic acids release calcium Ca2+-dependent Ca+2 mammalian mRNA proteins mouse murine hepatoma Hepa-1c1c7 MCF-7 Hep-G2 HL-60 |
11.138498242089
|
| 10569 |
Ellagic Acid
|
|
476-66-4 |
≥95%
|
|
|
2010-10-13
|
8.133806015960
|
ellagic-acid
|
Lagistase; TBBD; Gallogen
|
polyphenols, antioxidants, cancers inflammation cytochrome P450s CYP450 epigenetics genes expression histones modifications alizarin yellow G 91006 elagostasine 77415-21-5 124590-32-5 PRMTs inflammatory anti-carcinogenic anti-mutagenic organ-preserving antimutagenic antiinflammatory
Acid Benzoaric Benzoaric Acid
Acid Ellagic Ellagic Acid |
8.133806015960
|
| 75780 |
HET0016
|
|
339068-25-6 |
≥98%
|
|
|
2005-01-31
|
54.900193370165
|
het0016
|
N-hydroxy-N'-(4-n-butyl-2-methylphenyl)Formamidine
|
20-HETEs kidney cytochromes CYP450 hypertension cerebral vascular diseases metabolites arachidonic acids liver CYP4F inhibitors inhibition inhibits CYP4A CYP2C9 CYP2D6 CYP3A4 cyclooxygenases COX PGHS prostaglandins synthases EETs epoxyeicosatrienoic |
54.900193370165
|
| 10009026 |
homo-Tienilic Alcohol
|
|
236735-89-0 |
>95%
|
|
|
2006-07-12
|
10.003977900552
|
homo-tienilic-alcohol
|
|
SPI-BIO SPIBIO substrates CYP450 CYP-450-2C18 CYP-2C18 CYP2C18 cytochromes M02002 |
10.003977900552
|
| 75650 |
Hyperforin
|
|
11079-53-1 |
≥90%
|
|
|
|
51.111450276243
|
hyperforin
|
|
St. John's Wort Johns herbal herbs lipid signalling mediators cyp450-2D6 cytochromes cyp-2D6 steroid receptors SXR CYP-450-2D6 neuroscience endocrinology |
51.111450276243
|
| 75770 |
MS-PPOH
|
|
206052-02-0 |
≥98%
|
|
|
2007-02-23
|
32.007127071823
|
ms-ppoh
|
|
CYP450 cytochromes epoxidase activity inhibitor inhibition inhibits microsomal enzymes endocrinology |
32.007127071823
|
| 9000537 |
N-Desethylamiodarone (hydrochloride)
|
|
96027-74-6 |
≥95%
|
|
|
2009-10-07
|
5.834254143646
|
n-desethylamiodarone-hydrochloride
|
MDEA
|
substrates CYP3A4 metabolites amiodarone cytochromes CYP-3A4 CYP 3A4 |
5.834254143646
|
| 75760 |
PPOH
|
|
206052-01-9 |
≥99%
|
|
|
|
56.620497237569
|
ppoh
|
|
selective epoxygenases inhibitors inhibits acetylenic fatty acids cytochromes CYP450-4A2 CYP450-4A3 CYP450-4A1 CYP-450-4A2 CYP-450-4A3 CYP-450-4A1 CYP-4A2 CYP-4A1 CYP-4A3 endocrinology |
56.620497237569
|
| 13293 |
Rhapontigenin
Exclusive
|
|
500-65-2 |
≥98%
|
|
✓ |
2009-11-10
|
25.833729281767
|
rhapontigenin
|
|
resveratrols antioxidants cancers cytochromes P450 CYP450 proliferation anti cancers anti-oxidants |
25.833729281767
|
| 10008517 |
Tienilic Acid
|
|
40180-04-9 |
≥99%
|
|
|
2006-05-11
|
28.707476979741
|
tienilic-acid
|
|
substrates CYP450 CYP-450-2C9 CYP-2C9 CYP2C9 cytochromes M02001 CYP2C10 liver oxidation |
28.707476979741
|
| 10038 |
TMS
|
|
24144-92-1 |
>98%
|
|
|
|
38.985359116022
|
tms
|
2,3',4,5'-Tetramethoxystilbene
|
cytochromes inhibitors tetramethoxystilbene antimutagenesis CYP450-1B1 inhibits selective selectivity apoptosis cell growth |
38.985359116022
|