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Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…
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Research Area · Diabetes

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Item Number Product Sizes & Pricing CAS Purity Image Exclusive Introduction Date Mojo Plain Text Name Synonyms Keywords Interest
10010132 15-deoxy-Δ12,14-Prostaglandin J2-2-glycerol ester - ≥98% (isomer mixture) 2008-06-09 19.581055862492 15-deoxy-12-14-prostaglandin-j2-2-glycerol-ester 15-deoxy-Δ12,14-PGJ2-2-glycerol ester PPARgamma PPAR.gamma. PPARg PGD2 PGJ2 lipolysis prostaglandins adipocyte endocannabinoid metabolism diabetes obesity nuclear receptors COX-2 COX2 2-AG 2AG cannabinoids cbs synthetic 19.581055862492
11046 2-NBDG 186689-07-6 ≥98% (mixture of α and β) 2011-10-07 93.043431031821 2-nbdg NBD-Glucose fluorescence fluorescent probes glucose uptake cells viability contrast reagents neoplasia cancers diabetes flow cytometry microscopy 213484-93-6 93.043431031821
13265 4-hydroxy Nonenal Alkyne Exclusive 1011268-23-7 ≥98% ✓ 2010-06-16 136.023106200123 4-hydroxy-nonenal-alkyne Click Tag™ 4-HNE alkyne lipids peroxidation inflammation neurodegeneration atherosclerosis diabetes cancers click chemistry Click Tag™ 4-HNEs alkynes IT 136.023106200123
589320 8-hydroxy-2-deoxy Guanosine EIA Kit - 2008-05-21 664.292999210734 8-hydroxy-2-deoxy-guanosine-eia-kit 8-OH-dG ELISA Kit; DNA Damage EIA Kit solid plates oxidative injury stress aging cancers diabetes hypertension hydroxyl radicals peroxynitrite plasmas cells lysates tissues urine creatinine LC-MS liquid DNA damage kits EIAs chormatography mass spectrometry kits enzyme immunoassays elisas 8-OH-2-d 8OH2d 8 oxo deoxyguanine deoxyguanosine hydroxy ohdg 2 EIA/ELISA assays 8-ohdg 8ohdg 664.292999210734
10012708 A-922500 959122-11-3 ≥95% 2010-12-21 29.572946593001 a-922500 (1R,2R)-2-(4'-(3-phenylureido)biphenylcarbonyl)-cyclopentanecarboxylic acid triglyceride obesity insulin resistance inhibitors metabolic syndrome diacyl glycerolacyltransferase DGAT-1 DGAT1 DGAT 1inhibits inhibition A-922500 A922500 mice murine diet induced obesity DIO diet-induced Compounds, Biphenyl Biphenyl Compounds 29.572946593001
10008492 Adipose Triglyceride Lipase Blocking Peptide - 2006-06-27 1.265193370166 adipose-triglyceride-lipase-blocking-peptide ATGL; TG-hydrolase inducible PLA2-ζ; Desnutrin antibodies western blotting blots signaling signalling IHC WB formalin immunohistochemistry controls peptides proteins triglycerides energy storage mammalian adipose tissues caloric excess enzymes mobilization fatty acids catalyzes triacylglycerols diacylglycerols inhibition acylhydrolase activity diabetics pathology lung skeletal muscles testis heart brain kidney cells brown fat livers murine mouse macrophages HepG2 atherosclerosis 1.265193370166
10006409 Adipose Triglyceride Lipase Polyclonal Antibody - 2005-11-23 9.941270718232 adipose-triglyceride-lipase-polyclonal-antibody Phospholipase A2ζ; Desnutrin; ATGL antibodies antisera antiserum WB western blots blotting IHC immunohistochemistry triglycerides energy storage mammalian adipose tissues caloric excess enzymes mobilization fatty acids catalyzes triacylglycerols diacylglycerols inhibition acylhydrolase activity diabetics pathology lung skeletal muscles testis heart brain kidney cells brown fat livers murine mouse macrophages HepG2 atherosclerosis immunoblotting 9.941270718232
10010241 AICAR 2627-69-2 ≥98% 2008-02-25 204.096817679557 aicar NSC 105823; Acadesine; AICA Riboside AMPK lipids metabolism glucose fatty acids sterol HMG-CoA reductases inflammation cytokine iNOS COX-2 MnSOD glia macrophages TNF-.alpha. IL-1.beta. IL-6 aminoimidazole carboxamide ribonucleotide 204.096817679557
10010332 AMP-Deoxynojirimycin Exclusive 216758-20-2 ≥95% ✓ 2008-11-21 7.960876023905 amp-deoxynojirimycin Adamantane-pentyl-dNM; N-(5-adamantane-1-yl-methoxy-pentyl)-Deoxynojirimycin; AMP-dNM inhibitors inhibits inhibition ceramides lipids glycolipids glucosylceramide synthase glucosylceramidase β-glucosidase 2 glucosidase sphingomyelin deoxynorjirimycin nojirimycin inflammation antiinflammatory anit-inflammatory hapten colitis insulin sensitivity resistance SREBPs sterol genes expression cholesterol HepG2 cells 7.960876023905
580190 ANGPTL6 (human) EIA Kit New - 2012-01-10 48.569067273318 angptl6-human-eia-kit Angiopoietin-like protein 6 kits assays measures measurements angiopoietin-like proteins ANGPTLs angiopoietin-related growth factors AGF ligands regulated regulation angiogenesis glucose lipids energy metabolisms ANGPTL1 ANGPTL2 ANGPTL4 ANGPTL5 ANGPTL3 ANGPTL7 N-terminal N-terminus coiled-coil domains C-terminal C-terminus fibrinogen-like angiopoietins receptors Tie2 proteins Tie1 hepatocytes angiogenesis arteriogenesis ERK1/2-eNOS pathways transgenic mice mouse systemic expenditure high-fat diet-induced obesity ob insulin resistance null diabetic fasting serums levels immunometric sandwich plasma cells cultures supernatants 48.569067273318
13523 Apelin-13 217082-58-1 ≥95% 2010-06-29 36.988508287293 apelin-13 ligands APJ receptors central nervous system cardiovascular functions fluid homeostasis neurosciences hypertension diabetes metabolic syndrome insulin HIV aids Peptide Factors Paracrine Paracrine Protein Factors Paracrine Peptide Factors Growth Factors 36.988508287293
13524 Apelin-36 252642-12-9 ≥95% 2011-04-04 34.961381215469 apelin-36 agonists receptors APJ cardiovascular functions fluids homeostasis hypertension insulin sensitivity apelin-17 apelins 17 13 36 apelin-13 HIV infections peptides mature G protein-coupled GPCR c-protein coupled 34.961381215469
10626 AS-1269574 Exclusive 330981-72-1 ≥98% ✓ 2011-01-17 7.888581952118 as-1269574 diabetes glucose insulin receptors pancrease b-cells b cells .beta.-cells beta-cells β-cells β GPR119 GPR-119 GPR 119 lysophosphatidylcholine LPC oleoylethanol amides OEA agonist Ethanolamines Aminoethanols 7.888581952118
10010266 BAY-11-7082 19542-67-7 ≥98% 2008-07-25 33.128187845303 bay-11-7082 inhibitors inhibits inhibition NFkB NF-.kappa.B NF-kB NF-kappaB TNF.alpha. TNFa TNFalpha I.kappa.B-.alpha. IkB-a IkappaB-alpha inflammation cytokine cell adhesion ICAM-1 ICAM1 VCAM-1 VCAM1 E-selection Eselection Bay 11-7082 BAY-117821 Bay117082 BAY 117821 33.128187845303
10009145 Bezafibrate 41859-67-0 ≥98% 2007-08-02 4.950850828729 bezafibrate Difaterol; Bezatrol; Bezalip; BM 15075; Benzofibrate PPAR PPAR.alpha. PPAR.delta. PPAR.gamma. agonist Pan-PPAR cholesterol atherosclerosis metabolic syndromes LDL HDL proliferator-activated receptors diabetes low-density high-density lipoproteins atherosclerosis cardiovascular PPARa PPARd PPARg endocrinology fibrate 4.950850828729
10489 Candesartan cilexetil 145040-37-5 ≥98% 2011-04-08 57.833971761817 candesartan-cilexetil TCV-116 angiotensin II receptors antagonists hypertension diabetes AT1 type 1 stress diastolic blood pressure anti-hypertensive antihypertensive 57.833971761817
71748 CAY10415 Exclusive 146062-49-9 ≥98% ✓ 2008-07-28 71.701507059545 cay10415 thiazolidinediones TZDs PPARgamma PPARg PPAR.gamma. antidiabetic anti-diabetic insulin blood glucose resistance lipogenesis peroxisome proliferators activated receptors 71.701507059545
10007875 CAY10499 Exclusive 359714-55-9 ≥98% ✓ 2006-07-25 12.579852670350 cay10499 obesity lipases diabetes triglycerides diacylglycerol inhibitors steroidogenesis spermatogenesis atherosclerosis HSL hormone sensitive endocrinology 12.579852670350
10009079 CAY10506 Exclusive 292615-75-9 ≥98% ✓ 2008-11-17 30.623618784530 cay10506 diabetes glucose metabolism TZDs PPARγ agonists α-lipoic acids anti-diabetic 30.623618784530
10009536 CAY10512 Exclusive 139141-12-1 ≥97% ✓ 2007-07-18 28.156942909760 cay10512 analogs resveratrol nuclear factors NFkB NF-.kappa.B immunity inflammation stress growth apoptosis trans-stilbene activation cancers NF-kB inhibition inhibtors inhibits atherosclerosis 28.156942909760
10009017 CAY10514 868526-38-9 ≥98% 2007-01-24 5.527983425414 cay10514 Methyl-8-hydroxy-8-(2-pentyl-oxyphenyl)-oct-5-ynoate peroxisome proliferator-activated receptors aromatics analogs 8-HETEs 8S-HETE 8(S)-HETE agonists PPARa PPARalpha PPAR.alpha. PPARg PPARgamma PPAR.gamma.atherosclerosis 5.527983425414
10012562 CAY10566 944808-88-2 ≥98% 2009-01-07 8.920441988950 cay10566 SCD1 long chain fatty acids monounsaturated type 2 two diabetes dyslipidemia obesity 8.920441988950
10008846 CAY10573 Exclusive 853652-40-1 ≥98% ✓ 2009-02-02 38.681650552486 cay10573 PPARs rosiglitazone diabetes PPARα PPARδ PPARγ 38.681650552486
13143 CAY10587 Exclusive 1082058-99-8 ≥98% ✓ 2009-07-02 14.766325966851 cay10587 free fatty acid receptor1 FFA1 GPR40 pancreatic b-cells glucose insulin diabetes obesity metabolic syndrome receptors 14.766325966851
13282 CAY10599 Exclusive 1143573-33-4 ≥98% ✓ 2009-07-21 39.161461019030 cay10599 thiazolidinedione PPARs PPARγ agonist rosiglitazones BRL 49653 BRL49653 BRL-49653 diabetes TZDs 39.161461019030
10009796 CAY10602 374922-43-7 ≥95% 2009-07-15 19.163443830570 cay10602 SIRT1 Activator 1 SIRTs sirtuins inflammation deacetylase NF-kB NFkB NF-κB NFκB 19.163443830570
10010250 Cellular Retinol Binding Protein 7 Polyclonal Antibody - 2007-10-16 5.946309392265 cellular-retinol-binding-protein-7-polyclonal-antibody Retinoid Binding Protein 7; cRBP7; RET7; Cellular Retinol Acid-Binding Protein IV western blots WB ICC immunocytochemistry micronutrient cell growth differentiation CRBPs RBP4 RBP7 atherosclerosis blotting immunoblotting IHC immunohistochemistry 5.946309392265
10007171 Cetaben 55986-43-1 ≥98% 2005-11-11 1.577348066298 cetaben Hexadecylamino-p-amino Benzoic Acid clofibrate peroxisomes proliferator-activated receptors PPARalpha PPAR.alpha.-independent hypolipidemic activity reduces reduction serums triglycerides cholesterols concentrations peroxisomal enzymes inhibits synthesis hepatoma HepG2 cells reversible changes Golgi morphology blocked esters inhibitors fibrates class atherosclerosis endocrinology 1.577348066298
10011286 Chenodeoxycholic Acid 474-25-9 ≥95% 2009-02-25 30.085602209944 chenodeoxycholic-acid Ulmenide; Kebilis; Anthropodeoxycholic Acid; Hekbilin; Fluibil; CDCA FXR biles acids cholesterol oxidative stress glutathione cancers atherosclerosis diabetes hyperlipidemia CDA 30.085602209944
13122 CHIR99021 252917-06-9 ≥98% 2011-02-18 100.590852407261 chir99021 CT 99021 GSK-3α GSK-3β inhibitors glucose metabolism insulin diabetes Wnt stem cells mice mouse CHIR-99021 CT-99021 CHIR 99021 CT99021 pyridines glucogen synthesis CHO-IR self-renewal 100.590852407261
10006790 ChREBP Blocking Peptide - 2007-06-06 3.025980662983 chrebp-blocking-peptide WBSCR14; Carbohydrate Response Element-binding Protein proteins diseases WB western blots blotting ICC immunocytochemistry transcription factors nutrients hormonal regulations genes encoding enzymes glucose metabolisms lipogenesis pathways domains nuclear localization signals NLS N-terminus polyprolines basic tissues livers kidneys adipose basal cytosols proteins nucleus dephosphorylations mouse fat HepG2 cells 3.025980662983
10010060 ChREBP Cell-Based Translocation Assay Kit - 2007-08-15 15.116227308603 chrebp-cell-based-translocation-assay-kit Carbohydrate Response Element-Binding Protein Cell-Based Translocation Assay Kit assays kits transcription factors TFs diabetes nutrients hormones hormonal regulation genes encoding enzymes glucose metabolisms lipogenesis dephosphorylated cytoplasm protein Ser196 nucleus liver obesity tolerance drugs discovery modulators sub-cellular localization ICC immunocytochemical stains staining antibody antibodies DylightTM Thermo Scientific, Inc. DyLightTM Pierce Biotechnology Inc. fluorescence fluorescent fluorometric endocrinology cell-based assay cell based assay cba 15.116227308603
10009524 ChREBP DBD (human recombinant) - >85% by SDS-PAGE 2007-04-12 1.953729281768 chrebp-dbd-human-recombinant GenBank Accession No. BC012925; Carbohydrate Response Element-binding Protein DNA Binding Domain; WS-bHLH; Williams-Beuren Syndrome Chromosome Region 14 EMSA electrophoretic mobility shift assays transcription factors proteins diabetes obesity insulin HLH MLXIPL MIO WBSCR14 endocrinology CAS number # 352845-69-3 1.953729281768
10009753 ChREBP DBD Western Ready Control - 2007-05-03 1.953729281768 chrebp-dbd-western-ready-control Carbohydrate Response Element-binding Protein DNA Binding Domain; WS-bHLH; Williams-Beuren Syndrome Chromosome Region 14 WB western blot western blotting Thr666 PP2A carbohydrate response element CRE L-type pyruvate kinase L-PK glucose Ser196 endocrinology 1.953729281768
71730 Ciglitazone 74772-77-3 ≥98% 45.614659811745 ciglitazone U-63287; ADD 3878 nuclear receptors antidiabetic diabetes thiazolidinedione PPAR gamma PPAR.gamma. Peroxisome Proliferator-activated receptors Ligands Binding domains antihyperglycemic atherosclerosis endocrinology 45.614659811745
700440 Coenzyme A Assay Kit - 2011-01-19 64.915859137686 coenzyme-a-assay-kit CoA Assay Kit kits assays measures measurements coenzymes biosynthesized enzymatic pantothenate vitamin B5 cofactors acyl groups carriers carbonyl-activating TCA cycles fatty acids metabolisms acetates acetyl-CoA acetyl-coenzymes A melatonin heme rat livers diabetes fasting hypolipidemic drugs fat diets tumors plasma serum urine europium chlorides tetracyclines periodic 64.915859137686
580200 CTRP3 (human) EIA Kit New - 2012-01-20 7.725669358266 ctrp3-human-eia-kit Complement C1q TNF-related Protein 3 kits assays EIAs ELISAs enzymes immunoassays measures measurements complements C1q TNF-related tumors necrosis factor-relateds proteins 3 secreted glycoproteins morphogenesis metabolisms cells functions cellular paralog adiponectins adipocytes leukocytes blood chondrogenic differentiations bone cartilage angiogenesis ERF1/2 signaling signalling adipokines mice mouse humans recombinants suppresses suppression hepatic livers glucose sugar C6H12O6 output inhibition inhibits inhibitors gluconeogenesis levels normal ob/ob obese/obese antagonizes lipopolysaccharides LPS toll-like receptors 4 TLR4 competitive serums plasmas cultures supernatants 7.725669358266
580120 CTRP5 (human) EIA Kit - 2011-08-02 6.277106353591 ctrp5-human-eia-kit C1QTNF; C1q tumor necrosis factor-α-related protein 5 C1q/tumors necrosis factors 5 superfamily genes untranslated membranes frizzled-related proteins MFRP bicistronic transcript mutations late-onset retinal degeneration LORD apical basal pigmented epithelium ciliary tissues neuroectodermal macular adipose blood glycoproteins trimers oligomeric complexes disulfide bonds N-terminal N-terminus cysteine residues extracellular recombinant activator adenosine monophosphates AMP-activated kinases AMPK cells GLUT4 glucose uptake serum obese diabetic mice mouse competitive plasma assays kits measures measurements EIAs ELISAs enzymes immunoassays 6.277106353591
700520 D-Lactate Assay Kit - 2011-02-23 77.929479519227 d-lactate-assay-kit kits assays measures measurements D(-)-Lactates stereoisomers blood exogenous fermented foods yogurt sauerkraut pickles gastrointestinal tract lactobacilli bifidobacteria cytosols cells glyoxylase I II pathways methylglyoxal glutathione S-D-lactoylglutathione L-lactate L(+)-lactate pyruvates dehydrogenases LDH liver D-a-hydroxy acid D-alpha-hydroxy D-α-hydroxy mammals enzymes humans murines mitochondrial mitochondria D-lactic acidosis metabolic serum neurotoxic fermentation carbohydrates kidneys short bowel syndromes jejunoileal bypass surgery diabetes infection ischemia trauma monogastric malabsorptive nutrient sepsis plasma urine saliva intracellular extracellular cell culture samples oxidation reduction NAD+ NADH 77.929479519227
700210 DPP (IV) Inhibitor Screening Assay Kit - 2009-05-27 105.254259921503 dpp-iv-inhibitor-screening-assay-kit Dipeptidyl exopeptidases IV DPPIV DPP4 enzymes CD26 cluster of differentiation T-cells activation antigens adenosine deaminase complexing 2 membrane-bound glycoproteins immune regulation signal transduction apoptosis kidneys small intestines placentas humans serums seminal fluids proteolytic derivatives serines X-prolines X-alanines dipeptides N-terminus N-terminal polypeptides growth factors chemokines neuropeptides vasoactive inhibitors inhibits inhibition oral antidiabetic agents glucose homeostasis glucoregulatory hormones glucose-dependent insulinotropics GIP glucagon-like peptide-1 GLP-1 gastric therapeutics Type 2 tumors cancers markers neoplasms assays kits measures measurements fluorescences fluorescent fluorogenics substrates Gly-Pro-Aminomethylcoumarin AMC 105.254259921503
10011296 (E)-Guggulsterone 39025-24-6 ≥98% 2009-12-03 2.875138121547 -e-guggulsterone anti-flammatory cancers FXR bile acids LDL cholesterol antiinflammatory atherosclerosis obesity diabetes inflammation farnesoid X receptors guggul trees 2.875138121547
10008884 Eicosapentaenoic Acid ethyl ester 86227-47-6 ≥98% 2009-01-29 70.995414364641 eicosapentaenoic-acid-ethyl-ester EPA-EE; EPA ethyl ester fish oils anti-inflammatory anitinflammatory cardiovascular polyunsaturated fatty acids PUFAs EPAs nutrition oxidation competitive inhibitors inhibits inhibition metabolism cholesterol triglycerides insulin resistance adiponectin high fat diet high-fat TNFα 70.995414364641
10010019 FABP2 Polyclonal Antibody - 2007-10-02 3.441397000789 fabp2-polyclonal-antibody I-FABP; Intestinal-Fatty Acid Binding Protein; Fatty Acid Binding Protein 2 WB western blots fatty acids FABPs lipophilic ligands metabolism polymorphism FABP2 IFABP obesity diabetes antibodies antiserum diabetic antisera atherosclerosis endocrinology blotting immunoblotting 3.441397000789
10009549 FABP4 (human recombinant) - ≥90% 2007-06-15 16.343603909902 fabp4-human-recombinant A-FABP; ALBP; Adipocyte-FABP; Fatty Acid Binding Protein 4; aP2; Adipocyte Fatty Acid Binding Protein cytosolic fatty acids lipophilic ligands tissues uptake metabolism intracellular trafficking lipid FABP-4 metabolic pathways cell growth differentiation bidirectional flux insulin epinephrine adipocytes atherosclerosis endocrinology 16.343603909902
9001068 FABP4 (human recombinant) FITC conjugated - ≥95% 2011-08-23 6.631610102604 fabp4-human-recombinant-fitc-conjugated ALBP; Adipocyte-Fatty Acid Binding Protein; A-FABP; FABP4 fatty acids adipocytes obesity insulin resistence sensitivity cardiovascular disease atherosclerosis inflammation FABP-4 6.631610102604
10010463 FABP4 (human recombinant) Western Ready Control - 2007-10-23 3.441008287292 fabp4-human-recombinant-western-ready-control Fatty Acid Binding Protein 4; Adipocyte-FABP; ALBP; FABP4; A-FABP fatty acids proteins western blots blotting WB binding proteins adipocytes atherosclerosis endocrinology immunoblotting 3.441008287292
10005191 FABP4 (mouse recombinant) - ≥95% 2005-07-27 6.236795580110 fabp4-mouse-recombinant Adipocyte-FABP; ALBP; Fatty Acid Binding Protein 4; A-FABP protein-only protein-4 endogenous exogenous lipophilic ligands uptake metabolism intracellular trafficking lipid metabolic pathways modulation cell growth differentiation antiparallel .beta. strands barrel fat cells specific facilitate bidirectional flux insulin epinephrine proteins recombinant binding adipocytes fatty acids agonists insulin hyperinsulinemia deficiency afabp adipocytes atherosclerosis endocrinology 6.236795580110
10009676 FABP4 (mouse recombinant) Western Ready Control - 2007-04-30 2.515782688766 fabp4-mouse-recombinant-western-ready-control ALBP; Fatty Acid Binding Protein 4; Adipocyte-FABP; A-FABP fatty acids proteins western blots blotting WB binding proteins adipocytes atherosclerosis 2.515782688766
10004888 FMOC-L-Leucine 35661-60-0 ≥98% 2010-07-19 25.064521886953 fmoc-l-leucine FMOC-Leu; NPC 15199; NSC 334290 peroxisome proliferator-activated proliferator activated receptors activates PPAR PPARg PPAR-g PPARgamma PPAR.gamma. PPAR-gamma PPAR-.gamma. PPARγ PPAR-γ PPAR γ adipocytes differentiation fatty acids uptake glucose metabolism agonist partial insulin resistance diabetes adipogenesis NPC15199 NSC334290 NPC-15199 NSC-334290 Leucine L-Isomer Leucine L Isomer L-Isomer Leucine L-LeucineLeucine 25.064521886953
700310 Free Fatty Acid Assay Kit - 2010-09-08 193.542559351549 free-fatty-acid-assay-kit FFA kits assays measures measurements acids triglycerides intestines hydrolyzed glycerols enzymes pancreas pancreatic lipases intestinal liposomes capillaries lymph systems blood plasmas serums hepatocytes adipocytes muscles fibers oxidized sugars glucagon fats proteins albumin FFA skeletal skeletons hearts livers pathophysiological obesity insulin resistance type 2 II diabetes pathogenesis insulin-stimulated peripheral glucose uptake beta cells oxidative stressproinflammatory effects NFκB nuclear factors inflammation resistances metabolic urine enzymatic reactions Acyl CoA synthetase ACS acylation coenzymes oxidases ACOD hydrogen peroxides H2O2 horseradish peroxidases HRP 10-aceyl-3,7-dihydroxyphenozazine ADHP fluorescence fluorescent resorufins 193.542559351549
11104 Fructose 1,6-bisphosphatase (human recombinant) New - ≥95% 2011-11-29 73.934855603793 fructose-1-6-bisphosphatase-human-recombinant FDPase; FBP1; F1,6BPase metabolism insulin non-insulin-dependent type 2 diabetes mellitus glucose kinases fructose 1,6-diphosphatase liver enzymes gluconeogenesis phosphofructokinase glycolysis lactate glycerol alanine NIDDM hyperglycemia 73.934855603793
10816 FTO (human) Monoclonal Antibody (Clone FT 86-4) - 2011-06-15 1.458563535912 fto-human-monoclonal-antibody-clone-ft-86-4 Fat Mass- and Obesity-associated Protein; FATSO antibodies antiserum serum western blot WB immunoblotting ELISA enzyme-linked immunosorbent assay immunoprecipitation IP genes mutation metabolic syndrome genotype type 2 diabetes FT 864 FT864 1.458563535912
10815 FTO (mouse) Monoclonal Antibody (Clone FT 342-1) - 2011-06-15 1.458563535912 fto-mouse-monoclonal-antibody-clone-ft-342-1 FATSO; Fat Mass- and Obesity-associated Protein antibodies antiserum serum western blot WB immunoblotting ELISA enzyme-linked immunosorbent assay mouse mice genes mutation metabolic genotype type 2 diabetes FT 3421 syndrome FT3421 1.458563535912
10814 FTO (mouse) Monoclonal Antibody (Clone FT 62-6) - 2011-06-14 0.729281767956 fto-mouse-monoclonal-antibody-clone-ft-62-6 FATSO; Fat Mass- and Obesity-associated Protein antibodies antiserum serum western blot WB immunoblotting ELISA enzyme-linked immunosorbent assay immunohistochemistry IHC immunoprecipitation IP mouse mice genes mutation metabolic genotype type 2 diabetes syndrome FT 626 FT626 0.729281767956
13068 Fucoxanthin Exclusive 3351-86-8 ≥98 ✓ 2010-01-29 9.742292817679 fucoxanthin α-Carotene carotenoids algae white adipose tissues WAT obesity weight gain uncoupling proteins 1 UCP1 thermogenesis diabetes type 2 glucose insulin all-trans Carotenoids Xanthophyll Xanthophyll Carotenoids Xanthophyllshyperinsulinemia 9.742292817679
10010622 Genipin 6902-77-8 ≥98% 2008-05-09 144.961325966851 genipin (+)-Genipin obesity diabeties glucose insulin mitochondria UCP2 pancreatic .beta. cells anti-inflammatory antiinflammatory angiogenesis inhibitors inhibits inhibition uncoupling proteins 2 un-coupling angiogenesis apotosis diabetes inflammation metabolism obesity 144.961325966851
11579 Glipizide New 29094-61-9 ≥98% 2012-05-08 154.627224753468 glipizide Sucrazide; Ozidia; Napizide; K 4024; Digrin; CP 28720; Glucotrol; TK 1320; Melizide; Aldiab 29094-66-4 38777-27-4 172964-66-8 dipazide glibenese glibetin glican glidiab glipid glipizid gluco-rite glucolip glucotrol glucotrol Xl glucozide glupitel glupizide glyde glydiazinamide glynase mindiab minidab minidiab minodiab semiglynase TK-1320 TK1320 sulfonylurea blood-glucose insulin type II diabetes hypoglycemic drugs anti-diabetics endogenous β-cells potassium channels blood sugar mellitus acid acidic pH 154.627224753468
10990 Glucokinase (human liver recombinant) - ≥85% 2011-09-08 72.112744014733 glucokinase-human-liver-recombinant Human Hexokinase IV isoform 2; Hexokinase D; ATP:D-Hexose 6-Phosphotransferase GCK metabolism insulin non-insulin-dependent (type 2) diabetes mellitus glucose kinases GCK ATP-dependent phosphorylation glycolytic liver tissues neurons pancreatic cells pituitary endocrine hexokinases mutations active 72.112744014733
10989 Glucokinase (human pancreatic recombinant) - ≥90% 2011-09-08 72.873333333333 glucokinase-human-pancreatic-recombinant Human Hexokinase IV isoform 1; Hexokinase D; ATP:D-Hexose 6-Phosphotransferase GCK metabolism insulin non-insulin-dependent (type 2) diabetes mellitus glucose kinases GCK ATP-dependent phosphorylation glycolytic liver tissues neurons pancreatic cells pituitary endocrine hexokinases mutations active 72.873333333333
700300 Glucose-6-Phosphate Dehydrogenase Activity Assay Kit - 2011-07-28 112.190172018556 glucose-6-phosphate-dehydrogenase-activity-assay-kit G6PDH kits assays measures measurements Glucose 6 six phosphates Glucose-6-phosphates dehydrogenases cytosolic enzymes catalyzes pentose pathway ribose-5-phosphates precursor RNA ribonucleic acids DNA deoxyribonucleic ATP adenosine triphosphates CoA coenzymes A NAD nicotinamides adenine dinucleotides FAD flavin NADPH phosphates energy cells fatty oxidations lipids biosynthesis substrates oxidases macrophages polymorphonuclear leukocytes oxygen radicals pathogens intracellular metabolic de novo amino red blood RBC mitochondria pentose oxidative damage stress hemolytic anemia neonatal hyperbilirubinemia acute hemolysis chronic X-linked sex-linked hereditary genetics defect mutations G6PD genes malaria Plasmodium falciparum upregulated rat mouse murine obesity hyperglycemia hyperinsulinemia mediator insulin resistance post-translationally preneoplastic lesions tumors suppressors p53 human dimers fluorescence-based erythrocytes lysates tissues homogenates cultures samples 6-phospho-D-gluconate fluorometrics fluorescent 112.190172018556
10009582 Glucose Colorimetric Assay Kit - 2007-06-11 247.358159647013 glucose-colorimetric-assay-kit assays kits monosaccharides simple sugars carbohydrates blood stream energy cells hyperglycemia hypoglycemia Diabetes mellitus oxidase-peroxide d-gluconolactone delta-gluconolactone .delta.-gluconolactone plasma serum urine endocrinology 247.358159647013
600470 Glucose Uptake Cell-Based Assay Kit New - 2011-12-14 112.015499305408 glucose-uptake-cell-based-assay-kit assay kits measuring measurement CBAs C6H12O6 energy metabolisms adenosines triphosphates ATP cells homeostasis intestines blood muscles liver glycogens hydrolyzed levels transporters concentrations gradients energy-dependent uptakes gut kidneys rate hormones human growth factors insulin proliferation atrophy cancers pathways aerobic glycolysis anti-cancer effects drugs discovery fluorescent analogs 2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose 2-NBDG modulators cellular deoxyglucose cultured apigenin flavonoid 112.015499305408
700720 Glycerol Fluorometric Assay Kit New - 2012-01-17 54.625570025431 glycerol-fluorometric-assay-kit assays kits measures measurements flourometer fluorometry triglycerides storage fats metabolites energy metabolisms oxidations physiological pathological hydrolyzed free fatty acids FFAs blood glucose sugar gluconeogenesis lipolysis serums concentrations kinases x-linked inborn hyperglycerolemia glyceroluria fluorescence-based plasma phosphorylated glycerol-3-phosphates G-3-P adenosine-5'-diphosphates ADP oxidized phosphates oxidases dihydroxyacetones hydrogen peroxides H2O2 horseradish HRPs 1-acetyl-3,7-dihydroxyphenoxazine ADHP resorufin 54.625570025431
700480 Glycogen Assay Kit - 2011-08-02 96.860995889420 glycogen-assay-kit kits assays measures measurements polysaccharides storage glucose animal human cells polymers alpha(1,4) .alpha.(1,4) α(1,4) linkages units backbones livers muscles glycogenesis glycolysis brains stomachs granules cytosols cycles hepatocytes source available glucose-6-phosphatases blood kidneys glial WBCs white uterus pregnancy embryo abnormal metabolisms diabetes mellitus synthesis storage diseases von Gierke's Pompe McArdle's tissues hydrolyzed hydrolysis amyloglucosidases .beta.-D-glucose beta-D-glucose β-D-glucose oxidized oxidases hydrogen peroxides H2O2 horseradish peroxidases HRP 10-acetyl-3,7-dihydroxyphenoxazine ADHP resorufin 96.860995889420
10007206 GPR40 Blocking Peptide - 2007-04-12 2.731629834254 gpr40-blocking-peptide immunohistochemistry peptide insulin diabetes breast cancer 2.731629834254
10007205 GPR40 Polyclonal Antibody - 2007-04-04 8.616169429097 gpr40-polyclonal-antibody Free Fatty Acid Receptor; FFAR1; G Protein-Coupled Receptor 40 immunohistochemistry antibody insulin diabetes breast cancer endocrinology IHC 8.616169429097
10009374 GSK3β (Phospho-Ser9) Polyclonal Antibody - 2006-11-13 3.383314917127 gsk3-phospho-ser9-polyclonal-antibody Anti-Phospho-Ser9 Glycogen Synthase Kinase 3β antibodies proteins diseases antibodies antisera antiserum WB western blots blotting serine/threonine kinases regulation regulates signaling pathways GSK3a GSK3alpha GSK3.alpha. GSK3b GSK3beta inhibitors inhibition inhibits insulin Wnt Ser9 phosphorylation phospho-specific immunoblotting 3.383314917127
10008907 GW 9508 885101-89-3 ≥98% 2007-05-14 22.284447513812 gw-9508 agonists GPR40 GPR120 G protein receptors fatty acid glucose insulin MIN6 coupled endocrinology GW9508 22.284447513812
10011211 GW 9578 Exclusive 247923-29-1 ≥98% ✓ 2008-05-23 26.156961325966 gw-9578 atherosclerosis PPAR.alpha. PPARalpha PPARa LDLs lipids nuclear receptors fibrates diabetes obesity peroxisome perliforetior-activated 26.156961325966
10010559 HA-1077 (hydrochloride) 203911-27-7 ≥98% 2008-09-03 53.702559852670 ha-1077-hydrochloride Eril; Fasudil; AT-877 protein kinase inhibitors inhibits inhibition ROCK-II ROCKII PRK2 MSK1 MAPKAP-K1b vasodilation hypertension diabetes renal nephropathy cancers 105628-07-7 AT877 AT 877 hydrochloride dihydrochloride monohydrochloride HCl HA1077 HA 1077 53.702559852670
10010324 Harmine 442-51-3 ≥98% 2007-11-07 27.335911602210 harmine metabolic syndromes obesity diabetes PPAR.gamma. insulin sensitivity metabolism .beta.-carboline b-carboline alkaloids hyperglycemia signalling pathway inflammatory gene expression endocrinology 27.335911602210
11512 HMGB1 Monoclonal Antibody (Clone IMG19N10B7) New - 2012-01-16 0E-12 hmgb1-monoclonal-antibody-clone-img19n10b7 High Mobility Group Protein B1; HMG1 high mobility groups proteins family DNA-binding domains inflammation mediators DNA nuclear bindings sterile infection-associated responses Toll-like receptor 4 TLR4 advanced glycation endproducts RAGE IHC immunohistochemistry Western blot blotting flow cytometry FC WB 0E-12
11514 HMGB1 Monoclonal Antibody (Clone IMG19N12A1) - 0E-12 hmgb1-monoclonal-antibody-clone-img19n12a1 High Mobility Group Protein B1; HMG1 high mobility groups proteins B1 HMGB family DNA-binding domains nuclei nucleus cytoplasm cells mediators inflammation DNA nuclear bindings sterile infection-associated responses Toll-like receptors 4 TLR4 advanced glycation endproducts RAGE WB Western blots blotting 0E-12
11513 HMGB1 Monoclonal Antibody (Clone IMG19N15F4) New - 2012-01-16 0E-12 hmgb1-monoclonal-antibody-clone-img19n15f4 HMG1; High Mobility Group Protein B1 high mobility groups proteins B1 HMGB family nuclei nucleus cytoplasm cells mediators inflammation DNA nuclear binding sterile infection-associated responses Toll-like receptors 4 TLR4 advanced glycation endproducts RAGE WB Western blots blotting flows cytometry FC immunohistochemistry IHC 0E-12
11515 HMGB1 Polyclonal Antibody (aa 100-150) New - 2012-01-20 0E-12 hmgb1-polyclonal-antibody-aa-100-150 HMG1; High Mobility Group Protein B1 high mobility groups proteins B1 HMGB family DNA-binding domains nuclei nucleus cytoplasm cells mediators inflammation DNA nuclear bindings sterile infection-associated responses Toll-like receptors 4 TLR4 advanced glycation endproducts RAGE WB Western blots blotting flows cytometry FC immunohistochemistry IHC 0E-12
11516 HMGB1 Polyclonal Antibody (aa 25-75) New - 2012-01-30 0E-12 hmgb1-polyclonal-antibody-aa-25-75 HMG1; High Mobility Group Protein B1 high mobility groups proteins B1 HMGB family DNA-binding domains nuclei nucleus cytoplasm cells mediators inflammation DNA nuclear bindings sterile infection-associated responses Toll-like receptors 4 TLR4 advanced glycation endproducts RAGE WB Western blots blotting 0E-12
500340 Human Serum Albumin EIA Kit - 2009-07-16 118.368298342541 human-serum-albumin-eia-kit Albumin (human serum) EIA Kit; HSA ELISA Kit solid plates EIAs ELISAs enzymes immunoassays kits measures measurement renal kidneys blood proteins serums osmotic pressure buffering pH hormones fatty acids transports transportation microaluminuria macroalbuminuria disease non-diabetic nephropathy cardiovascular morbidity mortality creatinine assays 118.368298342541
10010676 Hydrochlorothiazide-d2 15N2 - ≥99% deuterated forms (d1-d2) 2009-05-02 0E-12 hydrochlorothiazide-d2-15n2 58-93-5 8049-49-8 125727-50-6 edema hypertension diabetes deuterated deuterium 0E-12
11208 KRN 7000 New 158021-47-7 ≥98% 2012-03-30 41.476023391813 krn-7000 immunology cancers lupus diabetes malaria tuberculosis NKT cells GalCer α-galactosylceramide KRN7000 KRN-7000 AGL582 AGL 582 synthetic immune tumors autoimmune 41.476023391813
16833 Lisinopril 76547-98-3 ≥98% 2009-03-09 2.875414364640 lisinopril MK 522; MK 521 inhibitors inhibits inhibition angiotensin I II ACE endothelin 1 nitric oxide renin hypertension diabetes 2.875414364640
10010785 (±)-Lisofylline 6493-06-7 ≥98% 2009-09-18 21.729350828728 -lisofylline CT-1501R; BL 194; LSF pentoxifylline phosphatidic acids shock sepsis antiinflammatory anti-inflammatory insulin diabetes IL-12 IL-12 inhibits inhibitions inhibitors IFN-γ IFNγ β-cell cell 39476-38-5 151852-35-3 21.729350828728
700510 L-Lactate Assay Kit - 2011-02-21 119.801918390639 l-lactate-assay-kit kits assays measures measurements L(+)-lactates stereoisomers humans metabolisms pyruvates ratios redox reduction oxidation cells NAD+ NADH dehydrogenases LDH glycolysis oxygen Cori cycles livers monocarboxylates tissues skeletal cardiac muscles kidneys substrates feedback inhibition lactic acidosis exercise convulsions sepsis respiratory failure HIV cancers diabetes serum plasma blood urine saliva intracellular extracellular cell culture samples 119.801918390639
10010236 ML-9 105637-50-1 ≥98% 2008-01-21 13.940220994475 ml-9 PKB Akt inhibitors inhibits inhibition serine/threonine kinase PKA P90S6 MAP kinases cancers anti-cancers insulin glucose transports calcium channels calmodulin intracellular smooth muscles asthma 13.940220994475
600480 NAD+/NADH Cell-Based Assay Kit New - 2012-02-29 105.680926438828 nad-nadh-cell-based-assay-kit Nicotinamide adenine dinucleotide/Nicotinamide adenine dinucleotide, reduced cells assay kits CBAs colorimetric measuring measurement Nicotinamide adenine dinucleotide/Nicotinamide adenine dinucleotide reduced cells oxidized cofactors redox oxidations reductions reactions electrons transporters cellular substrates enzymes acetyl groups proteins posttranslational respiratory functions citric acids cycles tricarboxylic TCA Kreb's ATP adenosine 5'-triphosphate oxidative phosphorylation metabolic activity biosynthesis de novo phosphoribosyltransferase NAMPT organs aging cytosolic mammalian death apoptosis signaling transcriptional metabolic disorders intracellular cultured alcohol dehydrogenases acetoaldehydes NAD kit NADP NADH NAD+ NAD-+ + 105.680926438828
10009661 N-Octadecyl-N'-propyl-sulfamide - ≥95% 2008-04-23 6.284806629834 n-octadecyl-n-propyl-sulfamide PPAR.alpha. PPARa PPARalpha OEA satiety obesity metabolism food intake triglyceride lipids activators appetite suppression 6.284806629834
600240 Orexin 1 Receptor STEP Reporter Assay Kit (Luminescence) Exclusive - ✓ 2010-03-31 10.428937998772 orexin-1-receptor-step-reporter-assay-kit-luminescence OX1R hypercretins 1 orexins 2 A orexin-2 systems regulates regulator sleep wake cycles feeding cardiovascular autonomic hypothalamic neuropeptides Orexins A Orexins B gut hormones secretions hypothalamus midbrains brainstems G protein-coupled receptors GPCRs orexin-1 OX1R orexin-2 OX2R orexin-A orexin-B sleep disorders narcolepsy humans animals rodents energy homeostasis pain stress antagonists drugs addictions withdrawals therapeutics obesity Surface transfection expression protocols solid phase transient transfection technology originus patents USPT US6897067 US6902933 US7056741 US 6897067 6902933 7056741 DNA deoxyribonucleases adherent cells receptor-mediated luminescent secretory alkaline phosphatases SEAP signal transduction cascades culture medium luminescence-based high throughput screening screens agonists 10.428937998772
600250 Orexin 2 Receptor STEP Reporter Assay Kit (Luminescence) Exclusive - ✓ 2010-03-31 9.883163122942 orexin-2-receptor-step-reporter-assay-kit-luminescence OX2R hypercretins 1 orexin 2 systems regulates regulator sleep wake cycles feeding cardiovascular autonomic hypothalamic neuropeptides Orexins A Orexins B gut hormones secretions hypothalamus midbrains brainstems G protein-coupled receptors GPCRs orexin-1 OX1R orexin-2 OX2R orexin-A orexin-B sleep disorders narcolepsy humans animals rodents energy homeostasis pain stress antagonists drugs addictions withdrawals therapeutics obesity Surface transfection and expression protocols solid phase transient transfection technology originus patents USPT US6897067 US6902933 US7056741 US 6897067 6902933 7056741 DNA deoxyribonucleases adherent cells receptor-mediated luminescent secretory alkaline phosphatases SEAP signal transduction cascades culture medium luminescence-based high throughput screening screens agonists 9.883163122942
13804 OU749 519170-13-9 ≥95% 2010-07-20 1.254530386740 ou749 γ-Glutamyl transferases γ-glutamyl transpeptidases glutathione markers liver dysfunction alcohol abuses biomarkers diabetes cardiovascular diseases cancers acivicin OU-749 OU 749 Mixtures Sulfonamide Sulfonamide Mixtures Sulfonamides 1.254530386740
10010374 p38 MAPK (Phospho-Thr180/Tyr182) Cell-Based Phosphorylation/Translocation Assay Kit - 2007-09-17 4.361010260458 p38-mapk-phospho-thr180-tyr182-cell-based-phosphorylation-translocation-assay-kit phosphorylation kits assays enzymes diseases asthma autoimmunity stress response nervous system fluorescence fluorescent fluorometric 4.361010260458
10218 PCSK9 Monoclonal Antibody (Clone 15A6) - 2008-10-29 12.266548802946 pcsk9-monoclonal-antibody-clone-15a6 Proprotein Convertase Subtilisin Kexin 9; NARC-1 antibodies proproteins serine protease lipoproteins LDLs low density neural apoptosis-regulated convertase 1 blotting ligands western immunoblotting WB blots 12.266548802946
10010254 Pentosidine 124505-87-9 ≥98% 2011-02-10 31.147900552486 pentosidine advanced glycation end products AGEs RAGE glycosylation diabetes uremia aging rheumatic arthritis biomarkers 31.147900552486
10004943 PEPCK Polyclonal Antibody - 2005-08-03 23.957546961326 pepck-polyclonal-antibody PEPCK-c; Pck1; Phosphoenolpyruvate carboxykinase proteins antibodies antisera antiserum WB western blots blotting hormones regulates enzymes steps gluconeogenesis catalyzing conversions oxaloacetate phosphoenolpyruvate mRNA liver kidney cortex white adipose tissue brown fat mammary gland lactation small intestine non-insulin-dependent diabetes mellitus streptozotocin-induced elevated activity isozymes cytosolic mitochondrial murine mouse rat endocrinology immunoblotting 23.957546961326
301707 PGC-1 Blocking Peptide - 2006-07-25 11.767955801105 pgc-1-blocking-peptide antibodies western blotting blots signaling signalling IHC WB formalin immunohistochemistry controls peptides proteins diseases proteins peroxisomes receptors gamma .gamma. PGC-1.beta. PGC-1.alpha. PRC N- C-terminus inducible transcriptional nuclear energy hepatic gluconeogenesis cholesterol homeostasis activates oxidative metabolisms tissues kidneys heart brown adipose skeletal muscles metabolic disorders type II 2 diabetes obesity 11.767955801105
101707 PGC-1 Polyclonal Antibody - 2005-10-12 27.193957810145 pgc-1-polyclonal-antibody PPARγ Coactivator 1; Peroxisome Proliferator-activated Receptor γ Coactivator 1 atherosclerosis proteins diseases antibodies antisera antiserum WB western blots blotting IHC immunohistochemistry peroxisomes receptors gamma .gamma. PGC-1.beta. PGC-1.alpha. PRC N- C-terminus inducible transcriptional nuclear energy hepatic gluconeogenesis cholesterol homeostasis activates oxidative metabolisms tissues kidneys heart brown adipose skeletal muscles metabolic disorders type II 2 diabetes obesity endocrinology immunoblotting 27.193957810145
11576 Phlorizin New 60-81-1 ≥98% 2012-05-01 153.727862912891 phlorizin NSC 2833; Floridzin Phloretin 2'-O-glucoside 2'-O-β-D-glucopyranoside 2'-glucoside 2'-β-D-Glucoside Phlorhizin Phloridzin Phloridzosid Phlorizine Phlorizoside Phlorrhizin 16055-86-0 52276-56-9 112318-65-7 sodium Na+ glucose co-transporters cotransporters transport 1 2 SGLT1 SGLT2 small intestines intestinal kidneys nephrons glomerulus Bowman's capsules reabsorption blood streams inhibition inhibits inhibitors plasma levels diabetes treatments diabetic apple trees bark blocks blocking renal absorption α-methyl-D-glucopyranoside α-MDG uptake humans COS-1 cells expressing expression hSGLT1 hSGLT2 competitive glucosuria resorption Na+/D-glucose 153.727862912891
71745 Pioglitazone 111025-46-8 >98% 24.079289660615 pioglitazone PPARgamma PPAR.gamma. anti-diabetic thiazolidinediones PPARalpha PPAR.alpha. RXRalpha RXR.alpha. agonists TZDs peroxisome proliferator-activated rosiglitazone receptors activation selectively selectivity 24.079289660615
10028 Pioglitazone (potassium salt) - >98% 36.995177584846 pioglitazone-potassium-salt PPARgamma PPAR.gamma. anti-diabetic thiazolidinediones PPARalpha PPAR.alpha. RXRalpha RXR.alpha. agonists TZDs peroxisome proliferator-activated receptors 36.995177584846
13643 PP242 1092351-67-1 ≥95% 2011-04-22 13.905426934432 pp242 mTORs mTORC1 mTORC2 inhibitors cancer leukemia rapamycin PP 242 PP-242 inhibited inhibition 13.905426934432
10009088 PPARα LBD (human recombinant) - ≥90% 2006-09-13 56.225207182320 ppar-lbd-human-recombinant Peroxisome Proliferator-activated Receptor α Ligand Binding Domain peroxisomes proliferator-activated receptors PPARs proliferator activated PPARalpha PPAR.alpha. PPARa PPARα PPAR-α PPAR-alpha alpha a α .alpha. PPAR-.alpha. PPAR-a recombinant proteins nuclear family families ligand activated trascription factors heterodimerize retinoic acids genes expression differentiation hNUC1 FAAR PPARβ PPARδ PPARγ liver skeletal muscles brown fats hearts kidneys livers fatty acids FAAH atherosclerotic lesions NSAIDs prostaglandins PGs leukotrienes B4 LTs LTB LTB4 WY 14643 WY-14643 WY14643 hypolipidemic CoA acyl-CoA oxidase enol-CoA hydratase dehydrogenase cytochromes P450 4A amino acids 170-430 E.coli gels electrophoresis coomassie statining western blots immunoblotting WB blotting 56.225207182320
61700 PPARγ FL (human recombinant from E. coli) - >90% by SDS-PAGE 2007-01-10 27.604745242480 ppar-fl-human-recombinant-from-e-coli Peroxisome Proliferator-activated Receptor γ Full Length (human recombinant) peroxisomes proliferator-activated receptors PPARs proliferator activated PPARgamma PPAR.gamma. PPARg PPARγ PPAR-γ PPAR-gamma gamma g γ .gamma. PPAR-.gamma. PPAR-g human recombinant nuclear receptors ligands activated ligand-activated activates transcription factors heterodimerizes retinoic acids gene expression differentiation hormones subtypes PPARα PPARδ hNUC1 PPARβ pathology obese obesity diabetes atherosclerosis cancers adipose tissues expressed colon immune systems retina DNA binding domains binds DBD transcription factor assays 10006855 gel electrophoresis coomassie stains staining fluorescent displacement ANS rosiglitazone 27.604745242480
10009987 PPARγ FL (human recombinant from Sf21 cells) - ≥80% by SDS-PAGE 2007-06-15 33.559779005524 ppar-fl-human-recombinant-from-sf21-cells Peroxisome Proliferator-activated Receptor γ Full Length (human recombinant from Sf21 cells) proteins binding enzymes PPAR.gamma. PPARgamma diseases obesity diabetes atherosclerosis cancers endocrinology 33.559779005524
10007941 PPARγ LBD (human recombinant) - ≥90% 2006-03-16 20.752995702885 ppar-lbd-human-recombinant Peroxisome Proliferator-activated Receptor γ Ligand Binding Domain peroxisomes proliferator-activated receptors PPARs proliferator activated PPARgamma PPAR.gamma. PPARg PPARγ PPAR-γ PPAR-gamma gamma g γ .gamma. PPAR-.gamma. PPAR-g recombinant proteins atherosclerosis diabetes endocrinology genes regulations metabolic syndrome nuclear receptors obese obesity PPAR proteins biochemistry hexahistidine-tagged tagged hexahistidine HIS-tag HIS-tagged HIS N-terminal PPARalpha PPAR.alpha. PPARα PPAR-alpha PPAR-.alpha. PPAR-α PPAR-delta PPAR-.delta. PPAR-δ PPARdelta PPAR.delta. PPARδ hNUC1 FAAR pathology diseases cancers domains LBD ligand binds binding DNA DBD RXR acid-like acid like heterodimerization thiazolidinedione rosiglitazone piolitazone insulin type II E. coli coomassie stains staining western blots blotting immunoblotting WB fluorescent 20.752995702885
10007685 PPARγ Ligand Screening Assay Kit - 2009-07-16 45.958161727774 ppar-ligand-screening-assay-kit Peroxisome Proliferator-activated Receptor γ FP-Based Ligand Screening Assay Kit - Green FP-based peroxisomes proliferator-activated receptors PPARs proliferator activated PPARgamma PPAR.gamma. PPARg PPARγ PPAR-γ PPAR-gamma gamma g γ .gamma. PPAR-.gamma. PPAR-g kits assys atherosclerosis TF diabetes drugs discovery discover endocrinology high throughput screens screening inflammations inhibitors inhibits inhibition metabolic syndromes metabolism nuclear receptors fluorescence FP-based FP based base ligands probes proteins isoforms γ1 γ2 γ-1 γ-2 1 2 adipose tissues colon immune systems retinas adipogenesis cells cellular differentiation insulin sensitization cancers fatty acids FAAH arachdionic 15-deoxy-DELTA12,14-prostaglandin 15-deoxy-DELTA12,14-PGs 15-deoxy-DELTA12,14-PGJ2 15 deoxy DELTA 12,14 PGs prostaglandins PGJ2 15-deoxy-Δ12,14-PGs 15-deoxy-Δ12,14-prostaglandins 15-deoxy-Δ12,14-PGJ2 15-deoxy-D12,14-prostaglandins 15-deoxy-D12,14-PGs 15-deoxy-D12,14-PGJ2 15-deoxy-.DELTA.12,14-prostaglandins 15-deoxy-.DELTA.12,14-PGs 15-deoxy-.DELTA.12,14-PGJ2 J2 thiazolidinediones TZD pioglitazone rosiglitazone agonists hyperglycemia hyperinsulinemia hypertriglyceridemia types 2 antidiabetics diabetes oral antagonists 45.958161727774
10006247 PPARδ Blocking Peptide - >70% 2004-11-09 2.702154696132 ppar-blocking-peptide PPARβ; Peroxisome Proliferator-activated Receptor δ; NR1C2 controls peptides western blots WB immunoblotting antibodies receptors PPARbeta PPAR.beta. lipid metabolism obesity special:month specialdiscount:15 specialstart:2008-02-01 specialend:2008-02-29 2.702154696132
10007451 PPARδ (human recombinant) - ≥95% 2005-07-29 13.889472068754 ppar-human-recombinant NUC1; PPARβ; Peroxisome Proliferative Activated Receptor δ; Nuclear Hormone Receptor 1; FAAR peroxisomes proliferator-activated receptors PPARs proliferator activated PPARdelta PPAR.delta. PPARd PPARδ PPAR-δ PPAR-delta delta .delta. δ PPAR-.delta. PPAR-d recombinant proteins human atherosclerosis cancers EMSA electrophoretic mobility shift assays endocrinology fluorescence metabolic syndrome nuclear obese obesity biochemistry transcription factors members retionic acids genes expression developments baculovirus Sf21 heterodimerize subtypes hNUC1 FAAR ubiquitously tissues mediator embryo implantation overexpression systems gels coomassie stains staining western blots WB immunoblotting 10006914 13.889472068754
101720 PPARδ Polyclonal Antibody - 2004-11-05 14.570783525866 ppar-polyclonal-antibody Nuclear Hormone Receptor 1; NUC1; FAAR; PPARβ PPAR.delta. PPAR.beta. PPARbeta peroxisome proliferator-activated receptors PPARdelta antibodies antisera nuclear receptors antiserum western blots blotting WB ICC immunocytochemistry IHC immunohistochemistry atherosclerosis endocrinology immunoblotting antibodies 14.570783525866
13000 Pterostilbene 537-42-8 ≥98% 2009-09-09 26.284175217048 pterostilbene 3',5'-Dimethoxy-4-Stilbenol; trans-3,5-Dimethoxy-4'-Hydroxystilbene resveratrol blueberries antioxidant PGE2 prostaglandins E2 cells proliferation ERK1/2 ERK 1/2 p38 MAPK PI3K/Akt NF-kB NFkB NF-κB NFκB AP-1 AP1 transcriptional activation cancers inflammation diabetes inflammatory 26.284175217048
13346 Rapamycin 53123-88-9 ≥95% 2009-10-21 44.025417638632 rapamycin Sirolimus immunosuppresssants transplants rejection inhibitors IL-2 lymphocytes B cells T FKBP12 mTOR mTORC1 cancer adipogenesis diabetes tuberous sclerosis cardiovascular diseases 44.025417638632
579070 Retinol Binding Protein 4 (human) Competitive EIA Kit - 2011-08-01 7.725669358266 retinol-binding-protein-4-human-competitive-eia-kit RBP4 binding proteins EIAs ELISAs enzymes immunoassays kits measures measurement insulin glucose homeostasis uptake skeletal muscles adipose tissues transporter 4 GLUT4 resistance vitamins A adipokines metabolic obesity syndromes cardiovascular diseases expression pro-inflammatory cytokines LDLs low-density lipoproteins cholesterols diet-induced obese hyperlipidemic hyperlipidemia dyslipidemia lipids metabolisms serums plasmas disorders 7.725669358266
13616 (R)-Lisofylline 100324-81-0 ≥98% 2010-05-27 1.331906077348 -r-lisofylline (R)-LSF; (-)-Lisofylline pentoxifylline phosphatidic acid shock sepsis anti-inflammatory IFN-γ IL-12 β-cell insulin diabetes interleukins 12 IL IFN-gamma 1.331906077348
13300 Ro 31-6045 113963-68-1 ≥98% 2009-07-28 11.995243484569 ro-31-6045 Bisindolylmaleimide V PKC kinase inhibitors S6K mitogen-stimulated proteins p70 p85 protein kinases C 11.995243484569
71740 Rosiglitazone 122320-73-4 ≥98% 156.772103540003 rosiglitazone BRL 49653 BRL49653 BRL-49653 ligands ppar.gamma. ppargamma receptors antagonists antidiabetic nuclear receptors diabetes peroxisome atherosclerosis endocrinology 156.772103540003
10011343 Rosiglitazone-d5 Maleate - >99% deuterated product 2009-04-04 37.339193370166 rosiglitazone-d5-maleate SPI TZDs thiazolinedions PPARg PPAR.gamma. PPARgamma selective ligand insulin resistance anti-inflammatory 37.339193370166
71742 Rosiglitazone (potassium salt) 316371-84-3 >98% 62.633134103465 rosiglitazone-potassium-salt BRL49653 BRL-49653 ligands ppar.gamma. ppargamma receptors antagonists antidiabetic nuclear receptors diabetes peroxisome salts thiazolidinediones atherosclerosis endocrinology 62.633134103465
10010247 SB 415286 264218-23-7 ≥98% 2008-10-29 12.584364640884 sb-415286 GSK3 GSK-3 PI3K signaling PI3K signalling glycogen synthase inhibitors inhibits inhibition neuron survival glycogen synthesis Chang human liver cells line potent selective sb415286 12.584364640884
10007682 Serum Retinol Binding Protein 4 Blocking Peptide - 2007-07-30 1.127071823204 serum-retinol-binding-protein-4-blocking-peptide pRBP Blocking Peptide; Plasma Retinol Binding Protein 4 Blocking Peptide; sRBP4 Blocking Peptide wb western blotting TTR serum type 2 diabetes sRBP plasma SRBP-4 blots proteins serums retinols insulin special:month specialdiscount:15 specialstart:2007-08-01 specialend:2007-09-30 RBP 1.127071823204
10007818 Serum Retinol Binding Protein 4 (human recombinant) - ≥95% 2006-10-05 24.262794001578 serum-retinol-binding-protein-4-human-recombinant RBP4; sRBP4 proteins vitamin A blood mammals .beta.-sheet-rich lipocalins hepatocytes plasma tetrameric transthyretin TTR adipocyte-derived adipocytes signaling type 2 diabetes insulin C-terminal terminus hexahistidine tag endocrinology 24.262794001578
10007681 Serum Retinol Binding Protein 4 Polyclonal Antibody Exclusive - ✓ 2007-08-03 4.724127071822 serum-retinol-binding-protein-4-polyclonal-antibody Plasma Retinol Binding Protein 4; pRBP; sRBP4 vitamin A wb western blotting type 2 diabetes lipocalin TTR transthyretin sRBP4 sRBP-4 proteins adipocytes signals signalling signaling insulin blots retinols serums RBP atherosclerosis endocrinology immunoblotting 4.724127071822
10009754 Serum Retinol Binding Protein Western Ready Control Exclusive - ✓ 2008-07-08 1.208563535911 serum-retinol-binding-protein-western-ready-control sRBP4; RBP4 proteins C-terminal western blots immunoblotting WB SRBPs hexahistidine His-tag His-tagged insulin resistance tyep 2 diabetes pathogenesis blotting 1.208563535911
13617 (S)-Lisofylline Exclusive 100324-80-9 ≥98% ✓ 2010-05-27 1.174447513812 -s-lisofylline (S)-LSF; (+)-Lisofylline pentoxifyllines phosphatidic acid shock sepsis anti-inflammatory IFN-γ IL-12 β-cell insulin diabetes antiinflammatory inflammatory inflammation inflammed 1.174447513812
10011671 Soluble Epoxide Hydrolase Inhibitor Screening Assay Kit - 2009-02-24 8.720009208103 soluble-epoxide-hydrolase-inhibitor-screening-assay-kit sEH Inhibitor Screening Assay Kit epoxides hydrolases sEHs inhibits inhibition assays kits fluorescence-based catalyzes hydrolysis exogenous endogenous vicinal diols substrates EETs epoxyeicosatrienoic acids vasodilatory vasodilation anti-inflammatory molecules therapy therapeutics hypertension vascular diseases PHOME (3-phenyl-oxiranyl)-acetic acid cyano-(6-methoxy-naphthalen-2-yl)-methyl ester 6-methoxy-2-naphthaldehyde excitation emission wavelengths a/b-hydrolases alpha/beta-hydrolases .alpha./.beta.-hydrolases enzymes homodimers C-terminal C-terminus animals models cyanohydrins cyanide ions 8.720009208103
10009239 SREBP-2 Cell-Based Translocation Assay Kit - 2007-04-17 38.243011505570 srebp-2-cell-based-translocation-assay-kit Sterol Regulatory Element-Binding Protein-2 Cell-Based Translocation Assay Kit sterol regulatory element binding proteins athersclerosis cholesterols fatty acids triglycerides phospholipids helix-loop-helix HLH transcription factors DyLight Pierce Biotechnology assays fluorescence fluorescent fluorometric cell-based assays cell based assay cba U18666A U 18666A U-18666A 38.243011505570
10009749 SREBP-2 Western Ready Control - 94 kDa (GST-tagged); 68 kDa (native) 2007-07-30 14.372972375690 srebp-2-western-ready-control Sterol Regulatory Element-binding Transcription Factor 2; Sterol Regulatory Element-binding Protein 2; SREBPF2 WB western blot helix loop bHLH fatty acids genes cholesterol regulatory HMG-CoA tissues E. coli SREBP2 SREBPF-2 transcription factors SREBP 2 atherosclerosis 14.372972375690
10026 T0070907 313516-66-4 ≥98% 44.348055248618 t0070907 T-0070907 nuclear receptors antagonist PPARgamma PPAR.gamma. peroxisome proliferator-activated selective selectivity thiazolidinediones TZDs inhibits inhibition inhibitors atherosclerosis endocrinology 44.348055248618
10010303 Triglyceride Colorimetric Assay Kit - 2007-10-31 362.235166605279 triglyceride-colorimetric-assay-kit assays kits triglycerides enzymes enzymatic hydrolysis water-insoluble lipids three fatty acids esterified glycerols blood serums lipoproteins chylomicrons very low density VLDLs dietary fats metabolisms energy diagnosis primary secondary hyperlipoproteinemia dyslipidemia triglyceridemia diabetes mellitus nephrosis livers obstruction endocrine colorimetric fluorometric plasmas coupled reaction systems 362.235166605279
700730 Triglyceride Fluorometric Assay Kit New - 2012-01-17 54.442971659504 triglyceride-fluorometric-assay-kit assays kits measures measurements flourometer fluorometry triglycerides water-insoluble lipids fatty acids esterified glycerols blood lipoproteins chylomicrons very low-density VLDLs dietary fats hydrolyzed hydrolysis free FFAs monoglycerides diglycerides intestines intestinal villi guts resynthesized capillary beds lipases adipose tissues storage stream oxidized mitrochondrias peroxisomes energy metabolisms levels lipids primary secondary hyperlipoproteinemia dyslipidemia triglyceridemia diabetes mellitus nephrosis livers obstructions endocrine disorders enzymatic hydrolysis fluorescence-based plasmas serums phosphorylated glycerol-3-phosphates G-3-P adenosine-5'-diphosphates ADP oxidized phosphates oxidases dihydroxyacetones hydrogen peroxides H2O2 horseradish HRPs 1-acetyl-3,7-dihydroxyphenoxazine ADHP resorufin 54.442971659504
71750 Troglitazone 97322-87-7 >98% 69.170685082872 troglitazone ResulinTM antidiabetic thiazolidinediones PPAR.gamma. PPARgamma ligands selective peroxisome proliferator-activated receptors diabetes TZD Resulin nuclear receptors atherosclerosis endocrinology 69.170685082872
10010245 U-83836E 137018-55-4 ≥98% 2008-07-08 0.386740331492 u-83836e antioxidant anti-oxidant oxidative injury stress free radicals ischemia diabetes a-tocopherol .alpha.-tocopherol 122003-11-6 PNU-83836E PNU83836E 0.386740331492
700320 Uric Acid Assay Kit - 2010-08-30 115.979321692528 uric-acid-assay-kit Urate Assay Kit kits assays measures measurement acids human purines metabolisms urine serum renal excretion excreted allantoin enzymes urate oxidases uricase genes obesity alcohol consumption hyperuricemia gout kidney stones metabolic syndromes hypertension cardiovascular diseases exercise-induced acute failure hypouricemia 115.979321692528
579000 Vaspin (human) EIA Kit - 2011-05-26 26.484758747697 vaspin-human-eia-kit Visceral Adipose Tissue-Derived Serpin A12 kits measures measurements EIA enzymes immunoassays adipokines insulin-sensitizing cDNA deoxyribonucleic acids white adipose tissues obese Otsuka Long Evans Tokushima Fatty OLETF rats absominal obesity type 2 diabetes serpins b-sheets beta-sheets β-sheets α-helices a-helices alpha-helices reactive site loops cognate serine proteases mRNA messenger ribonucleic visceral serum resistance pioglitazone biomarker plasma cells culture supernatants 26.484758747697
10010591 Wortmannin 19545-26-7 ≥98% 2008-11-21 30.065709170100 wortmannin KY 12420 phosphoinositide 3-kinase PI3K cells growth differentiations cancers motility inhibitors inhibits inhibition irreversible polo-like kinases PLK1 PLK3 mTOR DNA-PK DNAPK PL4K MLCK p38 MAPK 30.065709170100
13576 YM-201636 371942-69-7 ≥95% 2010-04-14 14.184116022099 ym-201636 PIKfyve phosphoinositide kinase PIK zinc finger domains phosphatidylinositol 3-phosphate PI3P PI(3,5)P2 membrane trafficking cytoskeleton inhibitors endosomal trafficking endosomes phagocytosis retrovirus virology adipocytes insulin glucose diabetes YM201636 YM 201636 Aminopyridines 14.184116022099
10009992 Zeaxanthin 144-68-3 ≥98% 2009-02-02 19.107532228360 zeaxanthin Zeaxanthol; Xanthophyll 3; Anchovyxanthin carotenoid degeneration AMDs luteins diabetes antioxidant oxidative injury injuries VEGFs macula 19.107532228360
71800 (Z)-Guggulsterone 39025-23-5 ≥98% 2009-12-01 1.169042357274 -z-guggulsterone anti flammatory cancers FXR bile acids LDL cholesterol tumors IL-6 STAT3 VEGF Akt 1.169042357274
700190 β-Hydroxybutyrate (Ketone Body) Assay Kit - 2009-06-02 205.986560554240 -hydroxybutyrate-ketone-body-assay-kit β-HB; 3-Hydroxybutyric Acid .beta.-hydroxybutyrate beta-hydroxybutyrate b-hydroxybutyrate b-HB beta-HB .beta.-HB β-HB 3-hydroxybutyric acids ketones body bodies acetoacetates acetones ketosis lipids metabolisms fasting exercise diets diabetes childhood hypoglycemia corticosteroids growth hormones deficiency intoxication alcohols salicylates organ failure ketoacidosis metabolic acidosis blood serums subclinical glucose diabetic coma hyperosmolar non-ketotic insulin hyperketonemia neurodegenerative diseases inhibits inhibition adipocytes lipolysis plasmas urine assays 205.986560554240
10007602 Δ2-cis Eicosenoic Acid 93772-82-8 ≥98% 2006-01-04 0E-12 -2-cis-eicosenoic-acid .alpha.,.beta.-unsaturated fatty acids a,b-unsaturated synthesis .DELTA.2-trans D2 extracted fresh wateer clams medical medicinal diabetes lipids metabolisms 2-octadecenoic livers blood sugars streptozocin-induced rats 0E-12
10007622 Δ2-trans Eicosenoic Acid - ≥98% 2006-01-04 0E-12 -2-trans-eicosenoic-acid .alpha.,.beta.-unsaturated fatty acids a,b-unsaturated synthesis .DELTA.2-cis D2 medical medicinal diabetes lipids metabolisms 2-octadecenoic livers blood sugars streptozocin-induced rats 0E-12
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