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Research Area · Histone Modification

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Item Number Product Sizes & Pricing CAS Purity Image Exclusive Introduction Date Mojo Plain Text Name Synonyms Keywords Interest
13828 3-Deazaneplanocin A 102052-95-9 ≥98% 2011-02-18 231.492454617205 3-deazaneplanocin-a DZNep; NSC 617989 EZH2 KMT6 methyltransferases histones cancer epigenetics panobinostat 3deazaneplanocin 3-cyclopentene-1,2-diol deriv Adenosine Adenocard 231.492454617205
10495 4-iodo-SAHA 1219807-87-0 ≥98% 2011-01-10 21.372640883977 4-iodo-saha anti-cancers HDACs inhibitors anti-proliferation 4-Hydroxy-5-iodo-3-nitrophenyl)acetyl 4-Hydroxy-3-iodo-5-nitrophenyl)acetyl 5-Iodo-4-hydroxy-3-nitrophenacetyl 5 Iodo 4 hydroxy 3 nitrophenacetyl Nitrohydroxyiodophenylacetate Hydroxyiodonitrophenylacetate Hapten NIP Acetyl Acetyl Hapten NIP NIP Acetyl Hapten NIP-Hapten NIP Hapten 21.372640883977
10547 4-pentynoyl-Coenzyme A (trifluoroacetate salt) Exclusive - ≥95% ✓ 2010-08-11 9.999471111111 4-pentynoyl-coenzyme-a-trifluoroacetate-salt Click Tag™ 4-pentynoyl-CoA 50347-32-5 click chemistry proteins acetylation posttranslational post-translational post translational modify modification acetyl-CoA acetyl-coenzyme A lysine histons acetyl click-it click it click tag click-tag 14-pentynoyl-coa(adamantyl) indole 9.999471111111
13725 Acetyl Lysine Polyclonal Antibody-biotin - 2009-12-04 1.385359116022 acetyl-lysine-polyclonal-antibody-biotin antibodies WB western blots immunoblotting blotting immunoprecipitation IP ELISA immunofluorescence IF proteins conjugated HATs HDACs histone acetyltransferases deacetylated deacetylases proteins cancers anti-cancer anticancer anti post-translational 1.385359116022
13726 Acetyl Lysine Polyclonal Antibody HRP Conjugate - 2009-12-04 1.385359116022 acetyl-lysine-polyclonal-antibody-hrp-conjugate antibodies WB western blots immunoblotting blotting immunoprecipitation IP ELISA immunofluorescence IF proteins conjugated HATs HDACs histone acetyltransferases deacetylated deacetylases proteins cancers anti-cancer anticancer anti 1.385359116022
13144 Anacardic Acid 16611-84-0 ≥98% 2010-02-12 5.862559731964 anacardic-acid 6-pentadecyl Salicylic Acid HAT histones acetylation P300 pCAF transcription NF-κB IκBα p65 6-pentadecyl salicyclic acids NSC 623096 cyclogallipharic 229596 333857 5.862559731964
10575 Apicidin New 183506-66-3 ≥98% 2012-01-27 21.579683293496 apicidin OSI 2040 funfal toxins malaria HDAC HAT histones deacetylase transcriptions epigenetics anticancer anti-cancer antiproliferation antiparasitic anti-proliferation anti-parasitic apicomplexan parasites HDAC3 HDAC-3 NcoR HDAC3/NcoR class I HDACs p21 WAF1/Cip1 WAF1 Cip1 gelsolin cells cycle morphology inhibits inhibitors inhibitions chromatin cancers deacetylase modification 21.579683293496
10946 Ash2L (human recombinant) - ≥90% 2011-06-29 12.972715102576 ash2l-human-recombinant Set1/Ash2 Histone Methyltransferase Complex Subunit Ash2 Isoform A; Absent, small, or homeotic discs 2-like epigenetics methyltransferases histones H3K4 genes regulations MLL proteins complex human homolog Drosophilia ash2 transcription 12.972715102576
13124 BIX01294 (hydrochloride hydrate) - ≥98% 2009-12-03 37.100217184225 bix01294-hydrochloride-hydrate euchromatin genes expressions epigenetics G9a histones methyltransferase HMTase embryogenesis imprinting lymphocytes development inhibitors proteins GLP stem cells 935693-62-2 37.100217184225
11507 BRD1 bromodomain (human recombinant) New - ≥95% 2012-03-01 15.723401238237 brd1-bromodomain-human-recombinant Bromodomain containing 1; DKFZp686F0325; BR140-like protein; BRL; BRPF1; BRPF2; Bromodomain and PHD finger-containing protein 2 BRD1 genes expression histones chromatin acetylation bromodomains epigenetics schizophrenia bipolar disorders BRD-1 BRDs 15.723401238237
600520 BRD4 bromodomain 1 TR-FRET Assay Kit New - 2012-04-25 87.870599080453 brd4-bromodomain-1-tr-fret-assay-kit kits assays measures measurements acetylations histones lysines epigenetics regulations genes transcriptions acetylated residues small proteins bromodomains nucleosomes chromatins structures expression BET family tandem Extra Terminal BRD2 BRD3 BRDT cells cellular inflammatory inflammation mitosis viral host virus viral/host interactions binds binding tails couples marks transcriptional targets promoters molecules inhibitors bromodomain/histone I-BET JQ-1 therapeutics human diseases complexes activated macrophages protection protects bacteria-induced sepsis lipopolysaccharides lipopolysaccharide-triggered endotoxic shock enantiomerically pure (+)-JQ1 (+)-JQ-1 2 bromodomain-peptides displacement inhibits inhibitors probes oncogenesis oncology cancers homogeneous TR-FRET time-resolved fluorescence resonance energy transfer characterization bromodomain/acetylated interactions fluorophores europium Eu3+ chelates biotinylated ligands allophycocyanin APC-labeled avidins biotins 87.870599080453
600530 BRD4 bromodomain 2 TR-FRET Assay Kit New - 2012-04-26 88.919981796503 brd4-bromodomain-2-tr-fret-assay-kit kits assays measures measurements acetylations histones lysines epigenetics regulations genes transcriptions acetylated residues small proteins bromodomains nucleosomes chromatins structures expression BET family tandem Extra Terminal BRD2 BRD3 BRDT cells cellular inflammatory inflammation mitosis viral host virus viral/host interactions binds binding tails couples marks transcriptional targets promoters molecules inhibitors bromodomain/histone I-BET JQ-1 therapeutics human diseases complexes activated macrophages protection protects bacteria-induced sepsis lipopolysaccharides lipopolysaccharide-triggered endotoxic shock enantiomerically pure (+)-JQ1 (+)-JQ-1 1 bromodomain-peptides displacement inhibits inhibitors probes oncogenesis oncology cancers homogeneous TR-FRET time-resolved fluorescence resonance energy transfer characterization bromodomain/acetylated interactions fluorophores europium Eu3+ chelates biotinylated ligands allophycocyanin APC-labeled avidins biotins 88.919981796503
11509 BRD9 bromodomain (human recombinant) New - ≥95% 2012-04-20 65.853947880323 brd9-bromodomain-human-recombinant Bromodomain-containing 9 BRD9 genes expressions histones chromatin acetylation bromodomains epigenetics BET domains transcription Extra Terminal domain BRDs BRDT inflammatory mitosis viral/host interactions Rhabdomyosarcoma antigen MU-RMS-40.8 65.853947880323
11548 BRDT bromodomain 1 (human recombinant) New - ≥95% 2012-03-01 15.723401238237 brdt-bromodomain-1-human-recombinant BRD6; CT9; RING3-like protein; Cancer/testis antigen 9; BRD-containing protein testis specific BRD-T genes expression histones chromatin acetylation bromodomains epigenetics BET domains Extra Terminal RING3 PEST Bromodomain testis specific BRDs BRD T 15.723401238237
11284 BRG1 bromodomain (human recombinant) New - ≥95% 2012-03-05 12.837710969321 brg1-bromodomain-human-recombinant BRG1-associated factor 190A; BAF190A Mitotic growth and transcription activator; ATP-dependent helicase SMARCA4; Protein BRG-1 BRG1 genes expressions histones chromatin acetylation bromodomains epigenetics SWI/SNF SWI SNF cancers tumors suppressors Protein brahma homolog 1 12.837710969321
11289 BRM bromodomain (human recombinant) New - ≥95% 2012-03-01 8.128331573859 brm-bromodomain-human-recombinant SWI/SNF ATPase; SMARCA2A/B BRD1 genes expressions histones chromatin acetylation bromodomains epigenetics SWI/SNF SWI SNF ATP dependent chromatin SWI/SNF-related, matrix associated, actin-dependent regulator of chromatin 8.128331573859
10009797 CAY10591 Exclusive 839699-72-8 ≥98% ✓ 2008-04-21 39.731274401472 cay10591 Sirtuin 1 Activator 3; SIRT1 Activator 3 p53 HDACs inhibits inhibitors inhibitions SIRTs sirtuins class III TNFalpha TNF.alpha. THP-1 cells anti-obesity anti-diabetic 39.731274401472
13156 Chaetocin 28097-03-2 ≥95% 2010-10-18 18.632886024146 chaetocin histones methyltransferases HMTs genes expressions epigenetics inhibitors oxidative stress cancers theoredoxin reductase-1 TrxR1 inhibits inhibition chetocin chaetocin A (+)-chaetocin piperazines 18.632886024146
13686 Chidamide 743420-02-2 ≥98% 2010-08-10 39.909907100471 chidamide HDACs histones deacetylase H3 acetylation colons cancers cells inhibitors inhibits inhibiton LoVo HT-29 HT29 HT 29 cycle arrest chidamides oncogenic signalling signaling kinases Benzamides 39.909907100471
11010 Core Histones (human) - ≥95% 2011-10-07 18.612207388499 core-histones-human HeLa Core Histones histones DNA nucleosomes chromatin HDAC HAT HMT HDEM H2A H2B H3 H4 proteins acetylation genes transcriptions methylation demethylation phosphorylation regulation 18.612207388499
10671 coumarin-SAHA - 98% 2011-02-03 15.155264404104 coumarin-saha coumarin-Suberoylanilide Hydroxamic Acid SAHA HDAC inhibitor fluorescent probe screening assay histone deacetylase inhibits inhibition Vorinostat Zolinza™ Pyrrolidinediones Succinimides Butanimides 15.155264404104
11012 Delphinidin chloride Exclusive New 528-53-0 ≥98% ✓ 2012-03-06 51.662269285860 delphinidin-chloride Ephdine diseases cancers cardiovascular tyrosines kinases vasorelaxation smooth muscles chlorides Cl vasorelaxants inhibitors inhibition inhibits EGFRs epidermal epidermis growth factors receptors HATs histones acetyltransferases anthocyanidins plants pigments anthocyanins blue red colors flowers fruits wines nitric oxides NOs vascular endothelium signaling signalling epithelial estrogens ERa ERalpha ER.alpha. ERα apoptosis cells death autophagy phagocytosis delphinidol 13270-61-6 IdB 1056 IdB-1056 51.662269285860
700390 Demethylase (Jumonji-type) Activity Assay Kit - 2010-05-26 28.154262474787 demethylase-jumonji-type-activity-assay-kit kits assays measures measurements histones nucleoproteins chromatins DNA deoxynucleic acids eukaryotic nucleus nucleosomal H3 H4 H2B H2A octamers amino termini acetylation phosphorylation ubiquitination methylation replication repair transcriptional activation repression dysregulation tumors suppressor genes cancers inhibitors enzymes catalyzes epigenetic marks methyls lysines arginines residues demethylases 1 JMJC JHDM1 JHDM2 JHDM3 JARID1 UTX/UTY cupin 2-oxoglutarate 2OG iron Fe(II) oxygenases hydroxylation JMJD2A JMJD2B JMJD2C JMJD2D JMJD2E JMJD2F fluorescence-based fluorescent cells lysates formaldehydes peptides substrates oxidation/decarboxylation acetoacetanilides ammonia H3K9(Me)3 28.154262474787
10770 DNA Methyltransferase 3L (human recombinant) - ≥95% 2011-06-08 2.540563835710 dna-methyltransferase-3l-human-recombinant DNMT3L; DNMT3-Like Protein DNA methyltransferases s-adenosylmethionine CpG methylation lysines proteins DNMT3a DNMT3b histones cysteine ADD PWWP mTase 2.540563835710
11178 DPY-30 (human recombinant) New - ≥95% 2012-01-05 14.152052839174 dpy-30-human-recombinant DPY-30-like protein; hDPY-30; SAF19 epigenetics methyltransferase histones H3K4 genes regulations MLL proteins subunits Ash2L MLL sore complex DPY30 methylation C. elegans XX mutations XO growth development homodimer monomers WDR5 WDR-5 WDR 5 RbBP5 basal rates DPY-30L DPY30L hDPY30 SAF-19 14.152052839174
10628 EED (human recombinant) - 95 2010-12-03 0E-12 eed-human-recombinant Embryonic Ectoderm Development 0E-12
10569 Ellagic Acid 476-66-4 ≥95% 2010-10-13 8.133806015960 ellagic-acid Lagistase; TBBD; Gallogen polyphenols, antioxidants, cancers inflammation cytochrome P450s CYP450 epigenetics genes expression histones modifications alizarin yellow G 91006 elagostasine 77415-21-5 124590-32-5 PRMTs inflammatory anti-carcinogenic anti-mutagenic organ-preserving antimutagenic antiinflammatory Acid Benzoaric Benzoaric Acid Acid Ellagic Ellagic Acid 8.133806015960
11076 Epigenetics Screening Library (96-Well) - 2011-11-09 25.669649126438 epigenetics-screening-library-96-well epigenetics libraries screens 25.669649126438
13487 EZH1 Polyclonal Antibody - 2009-07-14 0E-12 ezh1-polyclonal-antibody Western blots WB immunoblotting blotting 0E-12
10353 G9a (human recombinant) - ≥70% 2011-03-08 17.008637329521 g9a-human-recombinant EHMT2; Euchromatic Histone-Lysine N-Methyltransferase 2; KMT1C lysines methylation methyltransferases genes silencing repression proteins recombinants set domain-containing pluripotency H3K9 GLP active 17.008637329521
10755 G9a-like protein (human recombinant) - ≥95% 2011-10-13 18.767345337971 g9a-like-protein-human-recombinant Eu HMTase 1; EHMT1; GLP; Euchromatic Histone-Lysine N-Methyltransferase 1; KMT1D lysine methylation methyltransferase genes silencing repression SET domain histones modifications GLP H3K9 BIX-01294 UNC0638 inhibitors inhibits inhibition SAR monomethylate dimethylate BIX01294 BIX 01294 UNC-0638 UNC 0638 active 18.767345337971
10566 Garcinol 78824-30-3 ≥95% 2011-10-25 9.634610820401 garcinol Camboginol inhibits inhibitors inhibition histones acetyltransferases HATs p300 PCAF GCN5 neurogenesis stem cells apoptosis cancers antiinflammatory anti-inflammatory inflammation neuroscience genes expressions regulations epigenetics 9.634610820401
10782 Gcn5 (human recombinant) New - ≥80% 2011-12-05 24.213892198032 gcn5-human-recombinant Lysine acetyltransferase 2A; General control of amino acid synthesis protein 5-like 2; KAT2A; STAF97 epigenetics modifications histones acetylation cancers GNAT N-acetyltransferases enzymes STAGA TFTC SAGA ATAC H3K14 H3K9 H3K18 H4K8 H4K16 H3 H2B KAT2B p300/CBP associated factors Spt-Ada-GCN5-aceytltransferase Ada Two-A containing CoASH Gcn-5 N-acetyltransferases enzymatic subunits complexes proteins active 24.213892198032
10576 HC Toxin 83209-65-8 ≥95% 2010-11-10 24.217044198895 hc-toxin Toxin I (Helminthosporium carbonum) inhibitors histones deacetylases HDACs cancers genes regulation regulates regulators epigenetics HC-toxins cell-permable cells permable 15-lipoxygenase-1 15-LO-1 LOs lipoxygenase 15 1 tetrapeptides peptides helminthosporium carbonums cochliobolus maize pathogens Isomerases Amino Acid Acid Isomerases Amino Racemases Amino Acid Amino Acid Isomerases Acid Racemases Amino Amino Acid Racemases 24.217044198895
13504 HDAC11 Polyclonal Antibody - 2009-07-31 0.365911602210 hdac11-polyclonal-antibody Histone Deacetylase 11 wb western immunoblotting HDACs HAT histones antibodies peptides blots blotting 0.365911602210
10009231 HDAC1 (human recombinant) - >10% by SDS-PAGE 2006-12-06 28.775327141220 hdac1-human-recombinant Histone Deacetylase 1 HDAC 1 histones deacetylases enzymes HDACs catalyzes deacetylation nucleosomal nucleosomes transcription factors mediating mediators nuclear receptors co-repressor complexes regulatory pathways E2F TFIIE TFIIF NF-.kappa.B NF-kappaB NF-kB p300 Stat3 p53 retinoblastoma Rb proteins Class I yeast Rpd3 cells lines tissues chromatin structures development differentiation programmed death apoptosis angiogenesis inflammation dysregulation pathogenesis diseases cancers C-terminal C-terminus GST-tagged baculovirus Sf9 active 28.775327141220
13491 HDAC1 Polyclonal Antibody - 2009-07-24 0.306104972375 hdac1-polyclonal-antibody Histone Deactylase 1 HDAC-1 HDACs HDAC 1 antibodies WB western blots HATs immunoblotting blotting 0.306104972375
10009377 HDAC2 (human recombinant) - ≥70% by SDS-PAGE 2006-12-06 23.566802079947 hdac2-human-recombinant Histone Deacetylase 2 HDAC 2 histones deacetylases enzymes HDACs catalyzes deacetylation nucleosomal nucleosomes transcription factors mediating mediators nuclear receptors co-repressor complexes regulatory pathways E2F TFIIE TFIIF NF-.kappa.B NF-kappaB NF-kB p300 Stat3 p53 retinoblastoma Rb proteins Class I yeast Rpd3 cells lines tissues chromatin structures development differentiation programmed death apoptosis angiogenesis inflammation dysregulation pathogenesis diseases cancers C-terminal C-terminus his-tagged baculovirus Sf9 active 23.566802079947
10009232 HDAC3/NCOR2 (human recombinant) - ≥50% 2006-12-06 38.905749309392 hdac3-ncor2-human-recombinant Histone Deacetylase 3 HDAC 3 histones deacetylases enzymes HDACs catalyzes deacetylation nucleosomal nucleosomes transcription factors mediating mediators nuclear receptors co-repressor complexes regulatory pathways E2F TFIIE TFIIF NF-.kappa.B NF-kappaB NF-kB p300 Stat3 p53 retinoblastoma Rb proteins Class I yeast Rpd3 cells lines tissues chromatin structures development differentiation programmed death apoptosis angiogenesis inflammation dysregulation pathogenesis diseases cancers C-terminal C-terminus his-tagged baculovirus Sf9 active 38.905749309392
13493 HDAC3 Polyclonal Antibody - 2009-07-19 9.577400758665 hdac3-polyclonal-antibody Histone Deacetylase 3 HDACs antibodies HATs histones acetyltransferase deacetylases western blotting WB IP immunoprecipation ChIP immunoblots immunoblotting blots 9.577400758665
13494 HDAC4 Polyclonal Antibody - 2009-07-17 0.365911602210 hdac4-polyclonal-antibody Histone Deacetylase 4 WB Western blots immunoblotting IP ChIP antibodies HDACs HATs histones immunoprecipitation blotting 0.365911602210
10009379 HDAC5 (human recombinant) - ≥90% by SDS-PAGE 2006-12-06 32.033977900551 hdac5-human-recombinant Histone Deacetylase 5 HDAC 5 histones deacetylases enzymes HDACs catalyzes deacetylation nucleosomal nucleosomes transcription factors mediating mediators extranuclear receptors co-repressor complexes regulatory pathways E2F TFIIE TFIIF NF-.kappa.B NF-kappaB NF-kB p300 Stat3 p53 retinoblastoma Rb proteins Class IIa yeast Hda 1 catalytic domains amino acids N-terminal N-terminus nucleus cytoplasm cells chromatin structures development differentiation programmed death apoptosis angiogenesis inflammation dysregulation pathogenesis diseases cancers C-terminal C-terminus his-tagged baculovirus Sf9 active 32.033977900551
10009465 HDAC6 (human recombinant) - ≥80% 2007-06-14 22.816166595834 hdac6-human-recombinant GenBank Accession No. BC069243; Histone Deacetylase 6 HDAC 6 histones deacetylases enzymes HDACs catalyzes deacetylation nucleosomal nucleosomes transcription factors mediating mediators nuclear receptors co-repressor complexes regulatory pathways proteins Class II cells lines tissues chromatin structures development differentiation programmed death apoptosis angiogenesis inflammation dysregulation pathogenesis diseases cancers N-terminal N-terminus GST-tagged Sf9 active 22.816166595834
13499 HDAC6 Polyclonal Antibody - 2009-07-14 4.670386740331 hdac6-polyclonal-antibody Histone Deacetylase 6 HDAC-6 HDACs HDAC 6 antibodies WB western blots IP ChIP immunoblotting blotting immunoprecipitation 4.670386740331
13500 HDAC7 (Phospho-Ser155) Polyclonal Antibody - 2009-07-29 0.778358326756 hdac7-phospho-ser155-polyclonal-antibody Histone Deacetylase 7 antibodies MMP AR receptors matrix metalloproteinase androgens Nur77 histones deacetylases N-terminal immunoblotting blots western blotting WB 0.778358326756
19380 HDAC8 (human recombinant) - ≥95% 2009-04-03 20.800361240968 hdac8-human-recombinant HDAC 8 histones deacetylases enzymes HDACs catalyzes deacetylation nucleosomal nucleosomes transcription factors mediating mediators nuclear receptors co-repressor complexes regulatory pathways E2F TFIIE TFIIF NF-.kappa.B NF-kappaB NF-kB p300 Stat3 p53 retinoblastoma Rb proteins Class I yeast Rpd3 cells lines tissues chromatin structures development differentiation programmed death apoptosis angiogenesis inflammation dysregulation pathogenesis diseases cancers C-terminal C-terminus his-tagged baculovirus Sf9 active 20.800361240968
10009466 HDAC9 (human recombinant) - ≥95% 2007-06-14 16.569378453038 hdac9-human-recombinant GenBank Accession No. NM 178423; Histone Deacetylase 9 histones deacetylases enzymes HDACs catalyzes deacetylation nucleosomal nucleosomes transcription factors mediating mediators nuclear receptors co-repressor complexes regulatory pathways E2F TFIIE TFIIF NF-.kappa.B NF-kappaB NF-kB p300 Stat3 p53 HDAC 9 retinoblastoma Rb proteins Class I yeast Rpd3 cells lines tissues chromatin structures development differentiation programmed death apoptosis angiogenesis inflammation dysregulation pathogenesis diseases cancers C-terminal C-terminus his-tagged baculovirus Sf9 active 16.569378453038
600150 HDAC Cell-Based Activity Assay Kit - 2009-11-09 26.370505361597 hdac-cell-based-activity-assay-kit Histone Deacetylase Cell-Based Activity Assay Kit assays kits measuring measurement histones deacetylases lysines residues chromatin condensation transcriptional repression fluorescence deacetylation fluorescent inhibits inhibition enzymes fluorometric assays cancer modulators whole cells proteins lysine-specific HDAC1 homogenous inhibitor/activator TSA 26.370505361597
13535 Histone H2A Polyclonal Antibody - 2009-07-31 2.045745856353 histone-h2a-polyclonal-antibody H1 H2B H3 H4 histones antibodies DNA WB western blots immunoblotting ELISA enzyme-linked immunosorbent assays blotting 2.045745856353
10261 Histone H2A (Xenopus recombinant) - ≥95% 2011-10-13 9.979322603891 histone-h2a-xenopus-recombinant histones DNA nucleosome chromatin HDACs HAT H2A H2B H3 H4 octomers dimers genes transcription regulation acetylation methylation phosphorylation tetramers cores regulate ubiquitylation sumoylation biotinylation 9.979322603891
13538 Histone H2B (C-Term) Polyclonal Antibody - 2009-08-04 1.047823204419 histone-h2b-c-term-polyclonal-antibody histones antibodiesarginine lysine DNA WB western blots immunoblotting blotting 1.047823204419
13539 Histone H2B (N-Term) Polyclonal Antibody - 2009-08-04 1.047823204419 histone-h2b-n-term-polyclonal-antibody histones antibodies WB western blots immunoblotting DNA arginine lysine blotting 1.047823204419
10262 Histone H2B (Xenopus recombinant) - ≥95% 2010-03-19 10.538693250059 histone-h2b-xenopus-recombinant histones DNA nucleosomes chromatin HDAC HAT H2A H3 H4 proteins FL full legnth acetylation genes transcriptions methylation phophorylation regulation 10.538693250059
13784 Histone H3.3 Polyclonal Antibody - 2010-05-07 5.939042357274 histone-h3-3-polyclonal-antibody H3.3B; H3.3A; H3F3A; H3F3B histones antibodies immunohistochemistry IHC western blotting blots immunoblotting WB H2A H2B H3 H4 H-2A H-2B H-3 H-4 H 2A 2B 3 4 proteins nuclear DNA cells biology chromatin research epigenetics genes regulation modification histones 5.939042357274
10263 Histone H3 (human recombinant) - ≥95% 2010-03-22 33.692926130550 histone-h3-human-recombinant histones DNA nucleosomes chromatin HDAC HAT H2A H2B H4 acetylation methylation phosphorylation 33.692926130550
13540 Histone H3 (Phospho-Ser28) Monoclonal Antibody (Clone 117C826) - 2009-08-10 1.507163904235 histone-h3-phospho-ser28-monoclonal-antibody-clone-117c826 PHH3 H1 H2B H3 H4 histones antibodies WB western blots immunoblotting serine phosphos phosphorylation blotting 1.507163904235
10264 Histone H4 (human recombinant) - >95% 2010-09-07 8.883149171271 histone-h4-human-recombinant H4; Histone H4 8.883149171271
13543 Histone H4 Polyclonal Antibody - 2009-08-10 0.311850828729 histone-h4-polyclonal-antibody antibodies H1 H2A H2B H3 amino acids WB western blots immunblotting blotting 0.311850828729
13295 HNHA 926908-04-5 ≥98% 2009-09-03 23.011531893520 hnha Histone Deacetylase Inhibitor VI inhibitors inhibits inhibition histones deacetylase HDACs cancers fibrosarcoma HT1080 cells hyperacetylation p21 genes expressions transcription cycles arrest tumor growth murine xenograph human umbilical vein endothelial HUVECs tubes formation migration vascular endothelial factors VEGF retinal neovascularization angiogenesis 23.011531893520
13782 I2PP2A/SET Polyclonal Antibody - 2010-05-10 2.167182320442 i2pp2a-set-polyclonal-antibody Template-Activating Factor I; Inhibitor of granzyme A-activated DNase; Phosphatase 2A Inhibitor; PHAPII antibodies WB western blots blotting immunoblotting histones INHAT1 INHAT 1 coactivators transcription cells TAF1α TAF 1α TAF1β TAF 1β SETs INHAT-1 protein SET SET/I2PP2A TAF-1 TAF 1 TAF1 TAF-1beta TAF-1.beta. IGAAD 2.167182320442
11572 IOX1 New 5852-78-8 ≥97% 2012-05-09 95.770095150398 iox1 hypoxia 2-oxoglutarate Fe 2OG ferrous iron-dependent oxygenases collagen histones demethylation inhibitors inhibits inhibition H3K9me3 JMJD2A JMJD2E enzymes lipids metabolism nucleic acid diseases cancers oxygenases PHF8 PHD2 FIH 95.770095150398
10641 JGB1741 Exclusive 1256375-38-8 ≥98% ✓ 2011-06-20 17.811325966850 jgb1741 ILS-JGB-1741 inhibitors SIRT1 breasts cancers cells proliferation apoptosis p53 histones acetylation genes energy homeostasis regulation deacetylases sirtuins NAD+ inhibits inhibition SIRT2 SIRT3 ILS JGB 1,741 1741 SIRTs JGB-1741 JGB-1,741 17.811325966850
10336 JMJD2A (human recombinant) - ≥95% 2010-12-01 17.414083026396 jmjd2a-human-recombinant JHDM3A; KDM4A; Jumonji Domain Containing 2A lysine (K)-specific demethylase 4A Epigenetics Histone Demethylase chromatin regulator dioxygenase JmjC active 17.414083026396
700360 JMJD2A Inhibitor Screening Assay Kit - 2010-05-25 19.047282813814 jmjd2a-inhibitor-screening-assay-kit Jumonji Domain Containing 2A Inhibitor Screening Assay Kit kits assays measures measurements histones nucleoproteins chromatins DNA deoxynucleic acids eukaryotic nucleus nucleosomal H3 H4 H2B H2A octamers amino termini acetylation phosphorylation ubiquitination methylation replication repair transcriptional activation repression dysregulation tumors suppressor genes cancers inhibitors enzymes catalyzes epigenetic marks methyls lysines arginines residues demethylases 1 JMJC JHDM1 JHDM2 JHDM3 JARID1 UTX/UTY cupin 2-oxoglutarate 2OG iron Fe(II) oxygenases hydroxylation JMJD2A JMJD2B JMJD2C JMJD2D JMJD2E JMJD2F fluorescence-based fluorescent cells lysates formaldehydes peptides substrates oxidation/decarboxylation acetoacetanilides ammonia H3K9(Me)3 trimethylated 19.047282813814
10382 JMJD2A Polyclonal Antibody - 2010-04-15 13.421713730304 jmjd2a-polyclonal-antibody Lysine-Specific Demethylase 4A; KDM4A; Jumonji Domain Containing 2A lysine histones amino acids western blots blotting WB flow cytometry FC immunocytochemistry ICC cells lysate tissues control jumonjis JMJD2D 13.421713730304
11299 JMJD2A-Strep tagged (human recombinant) Exclusive New - ≥95% ✓ 2012-05-08 110.723606945540 jmjd2a-strep-tagged-human-recombinant KDM4A; Jumonji Domain Containing 2A; JHDM3A JMJD2A Jumonji domain demethylase epigenetics FDH KDM4Atrimethylllysine-specific JmjC protein hydroxylase Strep-Tactin StrepTactin Strep Tactin 110.723606945540
10335 JMJD2D (human recombinant) - ≥75% 2011-02-09 15.302862014869 jmjd2d-human-recombinant Jumonji Domain Containing 2D; KDM4D; Lysine-Specific Demethylase 4D epigenetics histones demethylases chromatin regulators dioxygenases JmjC proteins jumanjis active 15.302862014869
700370 JMJD2D Inhibitor Screening Assay Kit - 2010-05-25 19.603553147282 jmjd2d-inhibitor-screening-assay-kit Jumonji Domain Containing 2D Inhibitor Screening Assay Kit kits assays measures measurements histones nucleoproteins chromatins DNA deoxynucleic acids eukaryotic nucleus nucleosomal H3 H4 H2B H2A octamers amino termini acetylation phosphorylation ubiquitination methylation FLJ10251 replication repair transcriptional activation repression dysregulation tumors suppressor genes cancers inhibitors enzymes catalyzes epigenetic marks methyls lysines arginines residues demethylases 1 JMJC cupin 2-oxoglutarate 2OG iron Fe(II) oxygenases hydroxylation JMJD2A JMJD2B JMJD2C JMJD2D JMJD2E JMJD2F fluorescence-based fluorescent cells lysates formaldehydes peptides substrates oxidation/decarboxylation acetoacetanilides ammonia H3K9(Me)3 trimethylated 19.603553147282
10383 JMJD2D Polyclonal Antibody - 2010-04-16 23.467726140179 jmjd2d-polyclonal-antibody Jumonji Domain Containing 2D; Lysine-Specific Demethylase 4D; KDM4D lysine histones amino acids western blots blotting WB flow cytometry FC immunocytochemistry ICC cells lysate tissues control jumonjis JMJD2A 23.467726140179
11300 JMJD2D-Strep tagged (human recombinant) Exclusive New - ≥70% ✓ 2012-05-08 113.753599052880 jmjd2d-strep-tagged-human-recombinant KDM4D; Lysine-specific Demethylase 4D; Jumonji Domain Containing 2D JMJD2D Jumonji domain demethylase epigenetics FDH KDM4D JmjC proteins hydroxylase Strep Tactin StrepTactin Strep-Tactin 113.753599052880
11237 JMJD2E-Strep tagged (human recombinant) Exclusive New - ≥75% ✓ 2012-05-08 124.786284837323 jmjd2e-strep-tagged-human-recombinant Jumonji Domain Containing 2E; KDM4D-Like JMJD2D Jumonji domain demethylase epigenetics FDH KDM4D JmjC protein hydroxylase Strep-Tactin Strep Tactin StrepTactin KDM4DL 124.786284837323
13787 JMJD6 Peptide Affinity-Purified Polyclonal Antibody - 2010-05-13 4.662667001506 jmjd6-peptide-affinity-purified-polyclonal-antibody Jumonji Domain Containing 6; PTDSR antibodies western blots blotting immunoblotting nuclear protein JMJC domains histones H3 H4 H 3 H 4 H-3 H-4 chromatin epigenetics genes regulations modification 4.662667001506
11232 (−)-JQ1 Exclusive New 1268524-71-5 ≥98% ✓ 2012-04-23 107.848419726214 -jq1 BET bromodomain inhibitors inhibits inhibition BRD4 BRD2 transcription cancers extra terminal domains proteins BRD3 cells inflammatory inflammation genes expression mitosis viral viruses histones chromatin JQ 1 JQ-1 (±)-JQ1 ±-JQ1 107.848419726214
11187 (+)-JQ1 Exclusive New 1268524-70-4 ≥98% ✓ 2012-04-23 220.321955079750 -jq1 BET bromodomain inhibitors inhibits inhibition BRD4 BRD2 transcription cancers JQ-1 JQ 1 extra terminal domains BRD3 cells genes expression inflammatory inflammation viral viruses mitosis histones chromatin (±)-JQ1 ±-JQ1 10741 220.321955079750
10245 LSD1 (human recombinant) - ≥50% 2009-06-03 5.453445769118 lsd1-human-recombinant AOF2; NPAO; Lysine-Specific Demethylase 1; BHC110; p110b; KDM1 recombinant humans E.coli histones tumors suppressor CoREST lysine specific demethylase 1 proteins enzymes active 5.453445769118
700120 LSD1 Inhibitor Screening Assay Kit - 2008-10-16 24.063191420214 lsd1-inhibitor-screening-assay-kit Lysine-Specific Demethylase 1 lysines 4 demethylases histones residues repression transcription chromosomal DNA chromosomes inhibits inhibitors inhibition tumors suppressors activity cells cycles progression cancers fluorescent fluorescence enzymes enzymatic reactions H2O2 hydrogens peroxides peptides N-terminal tails H3 horseradish peroxidases ADHP resorufins assays 24.063191420214
13554 LSD1 Polyclonal Antibody (aa 100-150) - 2009-08-10 0.158195211786 lsd1-polyclonal-antibody-aa-100-150 Amine Oxidase (flavin containing) Domain 2 WIRM N-terminal antibodies WB western blots immunoblotting CoREST histones HDACs LSD1 AOF2 amine oxidase flavin containing domain 2 peptide affinity blotting 0.158195211786
13553 LSD1 Polyclonal Antibody (aa 400-450) - 2009-08-10 0.158195211786 lsd1-polyclonal-antibody-aa-400-450 antibodies WB western blots immunoblotting lysine histones demethylase FAD-binding SWIRM domains blotting 0.158195211786
13486 LSD1 Polyclonal Antibody (aa 450-500) - 2009-08-11 0.135595895816 lsd1-polyclonal-antibody-aa-450-500 WIRM N-terminal antibodies WB western blots immunoblotting CoREST histones HDACs LSD1 blotting 0.135595895816
13555 LSD1 Polyclonal Antibody (aa 800-850) - 2009-08-13 0.158195211786 lsd1-polyclonal-antibody-aa-800-850 WIRM N-terminal antibodies WB western blots immunoblotting CoREST histones HDACs LSD1 immunohistochemistry IHC paraffin AOF2 amine oxidase flavin containing domain 2 blotting 0.158195211786
13174 M 344 251456-60-7 ≥98% 2009-07-24 25.973145718231 m-344 D237; Histone Deacetylase Inhibitor III; MS 344 HDACs inhibitors inhibits inhibitions histones deacetylases HDAC1 HDAC6 cancers squamous carcinoma radiation cells cycles arrest apoptosis endometrial ovarian M344 MS344 M-344 MS-344 25.973145718231
13778 Metastasis Associated 1 Family Member 2 Polyclonal Antibody - 2010-05-04 8.700276243093 metastasis-associated-1-family-member-2-polyclonal-antibody p53 Target Protein in Deacetylase Complex; MTA2; MTA-L1 Protein; PID WB IHC western blotting blots immunoblotting immunohistochemistry MTA-2 MTA 2 MTA-1 MTA 1 MTA-3 MTA 3 HDAC2 HDAC-2 HDAC 2 HDAC1 HDAC-1 HDAC 1 proteins chromatin deacetylase activity activities northern p53 8.700276243093
13727 Methylated Lysine Polyclonal Antibody - 2009-12-04 9.272799263351 methylated-lysine-polyclonal-antibody WB western blots blotting immunoblotting IP immunoprecipitation ELISA antibodies SUV39H1 lysines proteins histones H3 genes expressions immunohistochemistry IHC 9.272799263351
13728 Methylated Lysine Polyclonal Antibody-biotin - 2009-12-04 6.933941068139 methylated-lysine-polyclonal-antibody-biotin WB western blots blotting immunoblotting IP immunoprecipitation ELISA antibodies SUV39H1 lysines proteins histones H3 6.933941068139
13729 Methylated Lysine Polyclonal Antibody HRP Conjugate - 2009-12-04 6.933941068139 methylated-lysine-polyclonal-antibody-hrp-conjugate WB western blots blotting immunoblotting ELISA antibodies SUV39H1 lysines proteins histones H3 6.933941068139
700140 Methyltransferase Colorimetric Assay Kit - 2009-04-07 30.225331001137 methyltransferase-colorimetric-assay-kit MT Colorimetric Assay Kit assays kits measures measuring monitoring monitors MTs methylation signal transduction biosynthesis repair gene silencing chromatin regulation S-adenosylmethionine SAM-dependent methyltransferases enzymatic cofactors AdoMet donor modifications DNA Alzheimer's diseases depression Parkinson's multiple sclerosis liver failure cancers enzyme-coupled AdoHcy positive control S-adenosylhomocysteine 30.225331001137
700150 Methyltransferase Fluorometric Assay Kit - 2009-04-08 26.105699252585 methyltransferase-fluorometric-assay-kit MT Fluorometric Assay Kit assays kits measures measuring monitoring monitors MTs methylation signal transduction biosynthesis proteins repair gene silencing chromatin regulation S-adenosylmethionine SAM-dependent methyltransferases enzymes enzymatic cofactors AdoMet donor proteins modifications DNA Alzheimer's diseases depression Parkinson's multiple sclerosis liver failure cancers enzyme-coupled AdoHcy positive control S-adenosylhomocysteine 26.105699252585
10658 MLL1 (human recombinant) New - ≥95% 2011-12-21 0.478496503496 mll1-human-recombinant Lysine Methyltransferase 2A; ALL1; Mixed Lineage Leukemia 1; HRX; KMT2a epigenetics methyltransferase histones H3K4 genes regulations MLL proteins complex subunits Ash2L WDR5 RbBP5 DPY30 mixed lineage leukemia methylation lysine HOX Pol II WAR c-terminal SET1 WIN binds binding DPY-30 WARD genomic 0.478496503496
10756 MLL1/WAR complex (human recombinant) New - ≥90% 2012-01-04 14.152052839174 mll1-war-complex-human-recombinant Mixed-Lineage Leukemia-1; MLL Core Complex epigenetics methyltransferases histones H3K4 genes regulations MLL proteins complex subunits Ash2L WDR5 RbBP5 DPY-30 upregulate transcriptions catalytic basal RNA polymerases chromosomes Pol II N-terminus leukemia Hox menin active 14.152052839174
10945 MLL1/WARD complex (human recombinant) New - ≥90% 2012-01-04 16.762033767337 mll1-ward-complex-human-recombinant Mixed-Lineage Leukemia-1; KMT2A; MLL Core Complex epigenetics methyltransferases histones H3K4 genes regulations MLL proteins complex subunits Ash2L WDR5 RbBP5 DPY-30 upregulate transcriptions catalytic basal RNA polymerases chromosomes Pol II N-terminus leukemia Hox menin WAR active 16.762033767337
13284 MS-275 209783-80-2 ≥98% 2009-11-05 37.997177716390 ms-275 Entinostat; SNDX 275 inhibitors histone deacetylases HDACs HDAC1 HDAC3 HDAC8 cyclin-dependent kinase inhibitor 1A p21 CIP1 WAF1 cell growth differentiation tumors cancers apoptosis adriamycin PARP Hsp90 ms275 MS 27-275 SNDX-275 SNDX275 MS27275 37.997177716390
11633 NCOR2/SMRT (human recombinant) New - ≥60% 2012-04-09 85.995493155963 ncor2-smrt-human-recombinant TRAC; T3 Receptor-Associating Factor; Nuclear Receptor Corepressor 2; Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor; CTG Repeat Protein 26; SMRT; SMAP270; Thyroid-Retinoic-Acid-Receptor-Associated Corepressor epigenetics histones deacetylases transcriptional regulations corepressor co-repressor complexes metabolism HDACs HDAC3 class I HDAC yeast Rpd DAD E2F TFIIE TFIIF NF-κB p300 Stat3 p53 retinoblastoma protein Rb protein differentiation cell death angiogenesis inflammation cancers inflammatory diseases 85.995493155963
10758 NSD2 (human recombinant) New - ≥90% 2012-02-01 5.306521739130 nsd2-human-recombinant Histone-lysine N-methyltransferase NSD2 isoform 1; MMSET; TRX5; Wolf-Hirschorn Syndrome Candidate 1; Nuclear Receptor SET domain-containing protein 2; Multiple myeloma SET domain-containing protein; Protein trithorax-5; WHSC1; KIAA1090 NSD2 SET-Domains Lysine methyltransferases chromatin WHSC1 MMSET WHSCH1-like multiple myeloma translocations histones H3 H4 H3K36 H4K44 H4K20 53BP1 dimethylation DNA damages NSDs NSD-2 active 5.306521739130
13176 Oxamflatin 151720-43-3 ≥95% 2010-11-16 28.367523020257 oxamflatin Metacept 3 HDACs histones deacetylases genes expressions morphology motility apoptosis cells cycles cancers reducing reduction proliferation Acids Hydroxamic Hydroxamic Acids Acid Hydroxamic Hydroxamic Acid 28.367523020257
10500 PAD4 (human recombinant) - ≥95% 2010-05-27 68.342983425414 pad4-human-recombinant Peptidylarginine Deiminase 4; Protein Arginine Deiminase 4 guanidino modifying enzymes citrillination histones deiminase MS multiple sclerosis Alzheimer's diseases glaucoma IOP intraocular pressure cancers peptidylarginine deiminase active 68.342983425414
10009115 pCAF Histone Acetyltransferase - ≥95% 2006-10-18 20.201293020038 pcaf-histone-acetyltransferase HAT; p300/(CREB binding protein) Associated Factor proteins binding GCN5 nuclear acetyltransferases C-terminal C-terminus acetyl-lysine N-terminal N-terminus histones H3 H4 transcriptional activators MyoD E2F1 p53 acetylates PTEN K125 K128 catalytic cleft in vivo enzymes cancers active 20.201293020038
13212 Pimelic Diphenylamide 106 Exclusive 937039-45-7 ≥98% ✓ 2009-09-30 18.483024134922 pimelic-diphenylamide-106 inhibitors inhibits inhibitions class I histone deacetylases HDACs SAHA HDAC1 HDAC2 HDAC3 HDAC8 II HDAC4 HDAC5 HDAC7 benzamides friedrich ataxia huntington disease 18.483024134922
11209 PRDM9 (human recombinant) Exclusive New - ≥65% ✓ 2012-01-11 24.814814814814 prdm9-human-recombinant PR Domain-containing Protein 9; MSBP3; ZNF899; PFM6; Meisetz histones methyltransferases zinc-fingers hotspots recombination genomes genetics meiosis trimethylation H3K4 nucleosomes PR/SET HTMase c-terminal C2-H2 PR domain zinc finger protein 9 24.814814814814
10350 PRMT1 (human recombinant) - ≥80% 2011-01-25 112.131740860628 prmt1-human-recombinant Protein Arginine Methyltransferase 1 PRMT1 brucei Prmt1 TbPRMT1 brucei Silencing Factors Transcriptional Transcriptional Silencing Factors Transcription Factors Repressor Molecules Proteins Repressor Repressor Proteins arginine methyltransferase histones modification glycine arginine rich GAR motifs SAM-dependent GST-tagged active 112.131740860628
10750 PRMT4 (human recombinant) New - ≥70% 2011-12-21 9.138927255985 prmt4-human-recombinant Protein Arginine Methyltransferase 4; CARM1; Coactivator-associated Arginine Methyltransferase 1 PRMT arginine methyltransferases epigenetics PRMT4 CARM1 SAM MMA aDMA Arg-17 Arg-26 proteins enzymes catalytic domains S-adenosyl-L-methionine histones H3 binding binds p160 SRC-1 SRC1 GRIP1 TIF2 pCIP RAC3 ACTR AIB1 TRAM1 nuclear receptors phosphorylation Ser217 hormones regulation lipids metabolism ω-NG,NG-dimethylarginine ω-NG-monomethylarginine active 9.138927255985
13552 PRMT4 Polyclonal Antibody - 2009-07-24 0E-12 prmt4-polyclonal-antibody CARM1; Protein Arginine Methyltransferase 4 antibodies WB western immunoblotting blots coactivator associated arginine methyltransferase 1 steroids receptors SRC proteins co-activators blotting 0E-12
10752 PRMT6 (human recombinant) New - ≥80% 2012-01-24 8.669677008074 prmt6-human-recombinant Protein Arginine Methyltransferase 6; HRMT1L6; Histone Arginine N-methyltransferase PRMT6; Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-like Protein 6 PRMTs arginine methyltransferases epigenetics PRMT6 histones SAM MMA aDMA H3R2 HMA H3K4 MLL HMGA1a active 8.669677008074
10947 RbBP5 (human recombinant) New - ≥90% 2012-01-06 14.152052839174 rbbp5-human-recombinant SWD1, Set1c WD40 repeat protein, homolog; Retinoblastoma binding Protein 5; RBQ3 epigenetics methyltransferases histones H3K4 genes regulation MLL proteins complex subunits nuclear WD40 domains tumors supressors RB cells proliferation E1A SET1 lysine MLL1 MLL1-4 dimethylation trimethylation H3 H3K4me2/me3 retinoblastoma-binding protein RBQ-3 RBBP-5 RBBP5 14.152052839174
10765 RIZ1 (human recombinant) New - ≥95% 2012-05-02 76.169567428508 riz1-human-recombinant KMT8; Retinoblastoma Protein-interacting Zinc Finger Protein; PR Domain Zinc Finger Protein 2; PRDM2 epigenetics cancer Histone H3K9 PR Domain Zinc-Finger histones methyltransferases RIZ-1 RIZ 1 SAM-dependent RIZs tumor suppressor apoptosis methylation 76.169567428508
10009929 SAHA 149647-78-9 ≥98% 2007-08-07 111.847118621265 saha Vorinostat; Suberoylanilide Hydroxamic Acid; Zolinza™ HDACs inhibitors cancers inhibits inhibition 111.847118621265
10675 SAHA-BPyne Exclusive 930772-88-6 ≥98% ✓ 2011-07-26 34.859079189686 saha-bpyne Suberoylanilide Hydroxamic Acid-BPyne click chemistry SAHA HDACs inhibitors inhibits inhibition probes SAHA BPyne epigenetics chromatin histones modification 34.859079189686
10443 SB 939 New 929016-96-6 ≥98% 2012-02-06 7.126284948937 sb-939 Pracinostat inhibits inhibitions inhibitor HDACs pan-HDAC panHDAC SB939 SB-939 histones deacetylase proliferation voronistat cancers tumors SAHA ovarian A2780 colon COLO205 HCT-116 prostate PC-3 7.126284948937
10572 Scriptaid 287383-59-9 ≥98% 2010-09-27 43.534185082873 scriptaid GCK 1026 histones deacetylases HDACs inhibitors inhibition inhibits cancers cloning cells arrest somatic nuclear transfers Scriptides trichostatin A mouse inbred strains somaic GCK-1026 GDK1026 hydroxylamines 43.534185082873
13780 SET7/9 (FL) Polyclonal Antibody - 2010-03-08 6.526586863106 set7-9-fl-polyclonal-antibody SET Domain-Containing Protein; KMT7; SETD7/9 antibodies SET 7/9 SET-7/9 7 9 histones H3 lysines 4 western blotting WB blots immunoblotting 6.526586863106
10320 SET7/9 (human recombinant) - ≥95% 2009-08-11 24.024535383748 set7-9-human-recombinant KMT7; SETD7/9; SET Domain-containing Protein 7/9 SET-7/9 SET 7/9 7 9 recombinant His-tagged proteins SETs methylation methyltransferase active 24.024535383748
700270 SET7/9 Methyltransferase Inhibitor Screening Assay Kit - 2009-12-04 24.872556970425 set7-9-methyltransferase-inhibitor-screening-assay-kit methyltransferases SET Domain-containing Protein 7/9 lysines 7 KMT7 methylation signal transduction biosynthesis proteins repair genes silencing chromatins S-adenosylmethionine SAM AdoMet methyl donors Alzheimer's depression Parkinson's Diseases multiple sclerosis liver cancers substrates histones histone 3 lysine residue 4 H3K4 p53 transcription factors TAF10 mono-methylated mono-methylase DNA damage acetylation human tumorigenesis inhibitors acceptor peptides S-adenosylhomocysteine S-ribosylhomocysteine adenine nucleosidase hypoxanthine deaminase urate hydrogen peroxide H2O2 ADHP 10-acetyl-3,7-dihydroxyphenoxazine resorufin fluorescence measures measurement assays kits 24.872556970425
13731 SET7/9 Polyclonal Antibody - 2009-11-25 35.149309392265 set7-9-polyclonal-antibody antibodies SET 7/9 SET-7/9 7 9 histones H3 lysines 4 western blotting WB blots immunoblotting 35.149309392265
600490 SET7/9 SAM-Screener Assay Kit New - 2011-12-21 41.633066544674 set7-9-sam-screener-assay-kit SET7/9 SAM-Binding Site Inhibitor Screening kits assays measures measurements chromatins posttranslational modifications histones DNA deoxyribonucleic acids lysines methylations epigenetics regulations genomes mono-methyltransferases MTs domains S-adenosyl-L-methionines SAM AdoMet co-factors epsilons amino groups Dot1 KMT7 domain-containing non-histones H3 TAF10 p53 viral Tat estrogens receptors alpha .alpha. α substrates humans diseases catalytic catabolism fluorescence EpiTrek polarizations fluorescent probes binding pockets endogenous cofactors sinefungin peptides high-throughput 41.633066544674
10319 SET8 (human recombinant) - ≥95% 2010-01-07 16.373424505296 set8-human-recombinant SETD8; SET domain-containing (lysine methyltransferase) 8; KMT5a; PR-Set7 SET-8 SET 8 recombinant His-tagged proteins SETs methylation methyltransferase MTs domain containing active 16.373424505296
10767 SETD2 (human recombinant) New - ≥95% 2012-01-19 10.685672191528 setd2-human-recombinant p231HBP; Huntington Interacting Protein B; KMT3A; HYPB epigenetics histones methyltransferases SET-domains containing SETD-2 SETD 2 huntingtin interacting proteins b HYBP trimethylation H3K36me3 mouse fibroblasts cells mono-methylation di-methylation WW hyperphosphorylation RNA polymerase II regulation diseases 10.685672191528
13277 (S)-HDAC-42 935881-37-1 ≥95% 2009-12-03 27.127075354659 -s-hdac-42 AR42 histones deacetylases HDACs cancers inhibitors prostate p21 Akt Bcl-XL tumors inhibition inhibits OSU-HDAC-42 27.127075354659
10010401 SIRT1 Direct Fluorescent Screening Assay Kit - 2008-02-26 51.236933701657 sirt1-direct-fluorescent-screening-assay-kit SIRT 1 assays kits measures sirtuins trichostatins A-intensive lysyl-deacetylases class III HDACs human homologs yeast SIR2 silent information regulators 2 tumors cancers suppressors inhibits inhitors inhibition apoptosis screening fluorescence activators fluorescent fluorometric 51.236933701657
10010991 SIRT1 FRET-Based Screening Assay Kit - 2008-02-19 20.010414364640 sirt1-fret-based-screening-assay-kit SIRT 1 assays kits measures sirtuins trichostatins A-intensive lysyl-deacetylases class III HDACs human homologs yeast SIR2 silent information regulators 2 tumors cancers suppressors inhibits inhitors inhibition apoptosis screening fluorescence activators fluorescent fluorometric 20.010414364640
10011190 SIRT1 (human recombinant) - ≥60% 2008-09-24 19.030764272559 sirt1-human-recombinant Silent Information Regulator 2; Sirtuin 1; SIR2-like Protein 1; SIR2L1; NAD-dependent Deacetylase 1 SIRT 1 SIRTs sirtuins HDACs DNA p53 proteins anti-cancers GST-tags GST-tagged sirtuin silent mating type information regulation 2 homolog 1 SIR2alpha sirtuin type 1 active 19.030764272559
700280 SIRT2 Direct Fluorescent Screening Assay Kit - 2009-12-10 40.755135213724 sirt2-direct-fluorescent-screening-assay-kit Nucleosomes chromosomal deoxyribonucleases DNA histones H2A H2B H3 H4 octameric cores transcription amino termini acetylation phosphorylation methylation ε-amino lysines acetyltransferases HATs chromatins genes activation deacetylases HDACs catalyzes hydrolytic acetyls sirtuins trichostatins A-insensitive lysyl-deacetylases class III catalyzes deacetylation nicotinamides O-acetyl-ADP-ribose NAD+ human SIRT1 SIRT2 SIRT3 SIRT4 SIRT5 SIRT6 SIRT7 cytoplasmic proteins H4 lysine-16 lysine-40 α-tubulin a-tubulin alpha-tubulin HDAC6 microtubules mitotic chromosomal hyperpolid cells tissues skeletal muscle heart oligodendroglia brain tumor suppressor gliomas Down-regulation gene chromosomal region diagnostic marker fluorescence-based inhibitors activators p53 Gln-Pro-Lys-Lys(ε-acetyl)-AMC recombinant NAD+ fluorescent fluorescence kits assays measures measurement 40.755135213724
10011191 SIRT2 (human recombinant) - ≥90% 2009-07-31 16.713987108655 sirt2-human-recombinant Silent Information Regulator 2; Sirtuin 2; SIR2-like Protein 2; NAD-dependent Deacetylase 2; SIR2L2 SIRT 2 SIRTs sirtuins HDACs DNA p53 proteins anti-cancers His-tagged His tag sirtuin silent mating type information regulation 2 homolog 2 sirtuin type 2 active 16.713987108655
10011194 SIRT3 (human recombinant) - ≥90% 2008-12-15 25.532397790055 sirt3-human-recombinant SIR2L3; Mitochondrial Nicotinamide Adenine Dinuclear-dependent Deacetylase; SIR2-like Protein 3; NAD-dependent Deacetylase 3; Silent Information Regulator 3; Sirtuin 3 SIRT 3 SIRTs sirtuins HDACs DNA p53 proteins anti-cancers GST-tags GST-tagged sirtuin silent mating type information regulation 2 homolog 3 sirtuin type 3 sir2-like 3 active 25.532397790055
10317 SIRT4 (human recombinant) - ≥95% 2010-01-06 9.452173112338 sirt4-human-recombinant Sirtuin 4; Silent Information Regulator 4; SIR2L4; SIR2-like Protein 4; NAD-dependent ADP-ribosyltransferase Sirtuin 4 SIRTs Sirtuins HDACs proteins His-tagged hexahistidines HDACS histone decatylases GDH glutamate dehydrogenase sirtuin silent mating type information regulation 2 homolog 4 sirtuin type 4 9.452173112338
10318 SIRT5 (human recombinant) - ≥90% 2009-07-31 18.494220994474 sirt5-human-recombinant Silent Information Regulator 5; Sirtuin 5; SIR2L5; SIR2-like Protein 5; NAD-dependent Deacetylase 5 SIRTs proteins HDACs CSP1 GST-tagged silent mating type information regulation 2 homolog 5 sirtuin type 5 18.494220994474
10315 SIRT6 (human recombinant) - ≥95% 2009-07-31 16.179944751381 sirt6-human-recombinant Sirtuin 6; NAD-dependent Deacetylase 6; Silent Information Regulator 6; SIR2L6; SIR2-like Protein 6 SIRTs Sirtuins HDACs proteins His-tagged hexahistidine silent mating type information regulation 2 homolog 6 sirtuin type 6 active 16.179944751381
10316 SIRT7 (human recombinant) - ≥85% 2009-12-22 13.922508287293 sirt7-human-recombinant SIR2L7; Sirtuin 7; Silent Information Regulator 7; SIR2-like protein 7; NAD-dependent deacetylase 7 SIRTs Sirtuins HDACs proteins His-tagged hexahistidine histone deacetylases silent mating types information regulators 2 homologs 13.922508287293
13477 SIRT7 Polyclonal Antibody - 2009-07-28 16.168250460404 sirt7-polyclonal-antibody Silent Information Regulator 7; Sirtuin 7; Sir2 antibodies SIRTs Sir2-like proteins WB western immunoblotting blots blotting sirtuins regulators 16.168250460404
13168 Splitomicin 5690-03-9 ≥98% 2010-07-15 13.082355958958 splitomicin 1-Naphthalenepropanoic Acid sirtuins Sir2p Sir-2p Sir 2p SIR2 NAD NAD+-dependent NAD-dependent dependent histone deacetylase activity activities genes regulations lifespan life-span life span yeast expression DNA replication inhibitor inhibits inhibition Hst1 Hst-1 Hst 1 HDACs chromatin research epigenetics regulation modification Sirs small molecules Pyrones 13.082355958958
10574 Suberohydroxamic Acid 38937-66-5 ≥98% 2010-09-28 21.781184392264 suberohydroxamic-acid SBHA; Suberic bis-Hydroxamic Acid histones deacetylases HDACs inhibitors genes expression regulation epigenetics nucleosomes HDAC1 HDAC3 differentiation cells cycle arrest apoptosis cancers suberodihydroxamic acid suberoyl bishydroxamic acid inhibited inhibition Warner-Lambert Brand of Mefenamic Acid Warner Lambert Brand of Mefenamic Acid Pharmascience Brand of Mefenamic Acid First Horizon Brand of Mefenamic Acid Parke Davis Brand of Mefenamic Acid Farmasierra Brand of Mefenamic Acid Ashbourne Brand of Mefenamic Acid Pinewood Brand of Mefenamic Acid Nu-Pharm Brand of Mefenamic Acid Nu Pharm Brand of Mefenamic Acid Chemidex Brand of Mefenamic Acid Gödecke Brand of Mefenamic Acid Clonmel Brand of Mefenamic Acid Antigen Brand of Mefenamic Acid Pfizer Brand of Mefenamic Acid Apotex Brand of Mefenamic Acid Rowa Brand of Mefenamic Acid Elan Brand of Mefenamic Acid APS Brand of Mefenamic Acid PMS-Mefenamic Acid PMS Mefenamic Acid Acid Mefenaminic Mefenaminic Acid Acid Mefenamic Mefenamic Acid Forte Ponstan Ponstan Forte Apo-Mefenamic Apo Mefenamic Nu-Mefenamic Nu Mefenamic ApoMefenamic NuMefenamic Pinalgesic Contraflam Ponalgic Parkemed Ponstel Ponstan Ponalar Mefacit Pontal Ponsyl Ponmel Dysman Coslan Mefic Mefac 21.781184392264
10763 SUV4-20H1 (human recombinant) - ≥60% 2011-07-13 32.081229281768 suv4-20h1-human-recombinant KMT5B; Suppressor of Variegation 4-20 Homolog 1; Lysine N-methyltransferase 5B methyltranferases histones H3K20 SET-domain containing s-adenosylmethionine s-adenosylhomocysteine lysines methylation epigenetics genes regulations KMT5B trimethylation H4K20 GRIP1 KMT5C KMT-5B KMT-5C KMTs active 32.081229281768
10764 SUV4-20H2 (human recombinant) - ≥95% 2011-06-06 32.572251381215 suv4-20h2-human-recombinant Suppressor of Variegation 4-20 Homolog 2; KMT5C methyltransferases histones H3K20 SET-domain containing s-adenosylmethionine s-adenosylhomocysteine lysine methylation epigenetics genes regulation SETD8 Pr-SET7 SUV420H2 SUV-420H2 SUV 420H2 SUV420H1 SUV-420H1 SUV 420H1 active 32.572251381215
10228 TAF 10 Peptide - 2009-03-23 14.982662983425 taf-10-peptide TAFII30; TATA Box Binding Protein (TBP)-Associated Factor; TBP-Associated Factor 10; TAF10 RNA Polymerase II proteins RNA polymerase II 14.982662983425
13788 TBLR1 Polyclonal Antibody - 2010-05-24 11.767955801105 tblr1-polyclonal-antibody Transducin β-Like 1X-Related Protein 1; F-Box-Like/WD Repeat-Containing Protein antibodies WB western blots blotting immunoblotting TBLR-1 TBLR 1 N-CoR NCoR N CoR SMRT nuclears receptors corepressors retinoid thyroid hormones HDACs histones deacetylases HDAC3 HDAC-3 3 TBL1X1R 11.767955801105
10783 TIP60 (human recombinant) New - ≥80% 2012-02-27 13.967022262195 tip60-human-recombinant Hs.6364; HIV-1 Tat Interacting Protein 60 kDa; Esa1; HTATIP; cPLA(2) Interacting Protein; KAT5; PLIP histones acetyl transferases HATs KAT5 KATs lysine acetyltransferases Tip-60 epigenetics histones modifications MYST Ataxia Telangiectasia Mutants p400 complex γH2AX iTIP60 Tip-60 13.967022262195
13789 TIP60 Polyclonal Antibody - 2010-05-24 7.423494475138 tip60-polyclonal-antibody KAT5; Lysine Acetyltransferase 5 antibodies TIP-60 TIP 60 TIPs HDACs western blots blotting immunblotting immunohistochemsitry IHC histones DAN proteins transcription factors 7.423494475138
10559 Tubastatin A (trifluoroacetate salt) Exclusive - ≥95% ✓ 2011-02-08 38.988967541436 tubastatin-a-trifluoroacetate-salt HDAC6 inhibitors histones deacetylases neuroprotection neurons epigenetics TFA inhibition inhibited neuronal protection α-tubulin alpha tubulin .alpha.tubulin a-tubulin tubastatin-A Acids Hydroxamic Hydroxamic Acids Acid Hydroxamic Hydroxamic Acid 38.988967541436
13631 UNC0224 Exclusive 1197196-48-7 ≥98% ✓ 2010-08-10 21.928835529111 unc0224 inhibitors inhibits inhibition histones methyltransferases genes regulation regulator chromatin remodeling UNC 0224 UNC-0224 G9a SET8 SET7/9 lysine HMTase 21.928835529111
10582 UNC0321 (trifluoroacetate salt) Exclusive - ≥95% ✓ 2011-03-15 13.187769964842 unc0321-trifluoroacetate-salt methyltransferases inhibitors histones genes regulation chromatin remodeling G9a HMTase inhibited inhibition potent selective MT SET7/9 SET8 PRMT3 JMJD2E 13.187769964842
10734 UNC0638 1255580-76-7 ≥98% 2011-05-03 22.094889502762 unc0638 methyltransferases inhibitors histones genes regulation chromatin remodeling inhibited inhibition G9a MT GLP PRMT 3 SUV39H2 SET7/9 SET8 inhibits H3K9 dimethylation MDA-MB231 22.094889502762
10774 UTX (human recombinant) - ≥85% 2011-05-24 19.139403519541 utx-human-recombinant Ubiquitously Transcribed Tetratricopeptide Repeat X; KDM6A epigenetics histones lysines demthylases chromatins regulators dioxygenases JmjC proteins enzymes recombinants UTY genes chromosomes active 19.139403519541
13033 Valproic Acid (sodium salt) 1069-66-5 ≥95% 2009-10-21 32.904732965009 valproic-acid-sodium-salt Sodium Valproate; 2-Propylvaleric Acid valeric acids anticonvulsant seizures inhibitors histones deacetylases HDAC glycogen synthase kinases GSK3 inositol-1,4,5-trisphosphate IP3 combination therapy cancers Alzheimer's diseases stem differentiation self-renewal 32.904732965009
10944 WDR5 (human recombinant) - ≥95% 2011-08-05 14.152052839174 wdr5-human-recombinant BMP2-induced 3-kb Gene Protein; SWD3, Set1c WD40 repeat protein, homolog; WD-Repeat Protein 5; BIG3 epigenetics binding proteins methyltransferase MLL complex subunits 14.152052839174
11549 WDR9 bromodomain 2 (human recombinant) New - ≥85% 2012-03-01 15.723401238237 wdr9-bromodomain-2-human-recombinant WD repeat-containing protein 9; BRD and WD repeat-containing protein 1 genes expressions histones chromatin acetylation bromodomains epigenetics BET domain WD repeats Brg1 SMARCA4 15.723401238237
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