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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Chemical Class · Inhibitors

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Item Number Product Sizes & Pricing CAS Purity Image Exclusive Introduction Date Mojo Plain Text Name Synonyms Keywords Interest
31570 12(S)-hydroxy-16-Heptadecynoic Acid Exclusive 148019-74-3 ≥98% ✓ 0.870055248619 12-s-hydroxy-16-heptadecynoic-acid acetylene inhibitors omega-hydroxylases cytochromes P450 hydroxy fatty acids .omega.-hydroxyases w-hydroxylases inhibits 12S-hydroxy-16-heptadecynoic 0.870055248619
13610 13,14-dihydro Prostaglandin E1 19313-28-1 >98% 50.608674033149 13-14-dihydro-prostaglandin-e1 PGE0; 13,14-dihydro PGE1 PGE0 metabolites 13,14-dihydro-PGE1 prostaglandins 50.608674033149
9000281 13,14-dihydro Prostaglandin E1-d4 - >99% deuterated product 2004-05-06 48.194263351749 13-14-dihydro-prostaglandin-e1-d4 13,14-dh PGE1-d4; Prostaglandin E0-D4 PGE0 metabolites 13,14-dihydro-PGE1 prostaglandins GC/MS deuterium isotopes PGA2-d4 internal standards deuterated LC/MS GC-MS LC-MS mass spectrometry gas liquid chromatography spectroscopy 48.194263351749
38610 13(S)-HODE 29623-28-7 ≥98% 73.895011838990 13-s-hode hydroxy fatty acids linoleic metastasis 13-HODEs 13S-HODEs 13(S)-HODEs 13(S)HODEs 73.895011838990
338610 13(S)-HODE-d4 139408-39-2 ≥99% deuterated product 39.474696132597 13-s-hode-d4 GC/MS deuterium isotopes 13-HODE-d4 standards 13S-HODE-d4 deuterated GC-MS LC/MS LC-MS 13-HODEs 13(S)-HODEs 13S-HODEs 13(S)HODEs hydroxy fatty acids 13(S)HODE-d4 mass spectrometry 39.474696132597
81520 1400W (hydrochloride) 214358-33-5 >98% 51.411961325967 1400w-hydrochloride selective iNOS inhibitors nitric oxide synthases (2HCl) inhibits dihydrochlorides 1400-w 51.411961325967
71220 1,4-DPCA 331830-20-7 ≥98% 2007-06-22 43.515290055249 1-4-dpca 1,4-dihydrophenonthrolin-4-one-3-Carboxylic acid HIF-1.alpha. normoxic HIF-.alpha. prolyl HIF-PH inhibitors collagen fibrosis 4-hydroxylase normoxia hypoxic hypoxia-inducible factor HIF1.alpha. HIF1alpha HIFPH inhibition inhibits 43.515290055249
10010468 15-Lipoxygenase Inhibitor 1 Exclusive 928853-86-5 ≥98% ✓ 2008-10-23 39.314433220636 15-lipoxygenase-inhibitor-1 15-LO Inhibitor 1 15-LOs inhibitors inhibits inhibition oxidation inflammation thrombosis cancers lipoxygenases pyrimidobenzothiazine antioxidants 39.314433220636
37720 15(S)-HEDE 92693-04-4 ≥98% 0.216500920810 15-s-hede hydroxy fatty acids 15S-HEDEs 15-HEDEs 15(S)HEDEs 15(S)-HEDEs 0.216500920810
34720 15(S)-HETE 54845-95-3 ≥98% 33.067837411207 15-s-hete soybean 15-LOs asthma airway 15-lipoxygenases monohydroxy fatty acids 15S-HETES 15-HETES arachidonic 15(S)-HETEs 15(S)HETEs potato polyunsaturated 15HETEs 33.067837411207
334720 15(S)-HETE-d8 84807-87-4 ≥99% deuterated product 39.003388581951 15-s-hete-d8 GC/MS deuterium isotopes 15-HETE-d8 standards 15S-HETE-d8 15(S)HETE-d8 deuterated GC-MS LC/MS LC-MS 15-HETEs 15(S)-HETEs 15S-HETEs 15(S)HETEs hydroxy fatty acids mass spectrometry 15HETE 39.003388581951
534721 15(S)-HETE EIA Kit - 73.417918968692 15-s-hete-eia-kit 15(S)-HETE ELISA Kit solid plates 15(S)-HETEs 15S-HETEs measures kits eias enzyme immunoassays ELISAs 15(S)HETEs 15HETEs assays 73.417918968692
10007251 15(S)-HETE Lipid Maps MS Standard 54845-95-3 ≥98% 2009-02-17 17.652116447088 15-s-hete-lipid-maps-ms-standard soybean 15-LOs asthma airway 15-lipoxygenases monohydroxy fatty acids 15S-HETES 15-HETES arachidonic 15(S)-HETEs 15(S)HETEs potato polyunsaturated MS mass spectrometry standards 15HETE 17.652116447088
36720 15(S)-HETrE 92693-02-2 ≥98% 39.608259668508 15-s-hetre DGLA 15-LOs metabolites 15-lipoxygenases 15-HETrEs hydroxy fatty acids 15(S)-HETrEs 15-HETrEs 15(S)HETrEs 39.608259668508
10080 16,16-dimethyl Prostaglandin A1 41692-24-4 >99% deuterated product 56.506436464088 16-16-dimethyl-prostaglandin-a1 16,16-dimethyl PGA1 16,16-dimethyl-pga1 prostaglandins metabolism-resistant analogs inhibits inhibition inhibitors viral replication HSV HIV-1 herpes simplex virus human immunodeficiency type 1 56.506436464088
13076 16(R)-Iloprost - ≥98% 2008-10-10 20.081736385161 16-r-iloprost prostacyclin platelet aggregation IP receptors EP vasodilation pulmonary hypertension stereoisomers inhibits inhibitors inhibition iloprosts PGI2 20.081736385161
13812 17β-hydroxy Wortmannin Exclusive - ≥98% ✓ 2010-05-18 31.334483732350 17-hydroxy-wortmannin phosphoinositide 3-kinase PI3K mTOR inhibitors inhibits inhibition inhibitory cancers 17-hydroxywortmannins 17-hydroxy wortmannins hydroxywortmannins PI3-K HWT phosphatidylinositol 31.334483732350
70510 1-Benzylimidazole 4238-71-5 >99% 0.859723756906 1-benzylimidazole thromboxanes synthases inhibitors inhibits imidizoles 0.859723756906
10011718 1-Deoxynojirimycin (hydrochloride) 73285-50-4 ≥95% 2008-08-25 31.284233681195 1-deoxynojirimycin-hydrochloride 1-dNM (hydrochloride); Moranoline (hydrochloride) .alpha.-glucosidases I II glycosylation glucosylation glucose pompe diseases antiviral agents HIV-1 HIV1 1dNM 1 31.284233681195
10954 1-NA-PP1 New 221243-82-9 ≥98% 2011-09-30 68.084160138534 1-na-pp1 PP1 Analog; 1-Naphthyl-PP1 inhibitors inhibits inhibition kinases mutated analogs sensitive v-Src vSrc c-Fyn cFyn CDK2 c-Abl cAbl mammalian yeast 1NMPP1 1NA-PP1 cells permeable tyrosine cell-permeable AS Src-family Src I338G v-Src-AS1 68.084160138534
13330 1-NM-PP1 221244-14-0 ≥95% 2009-07-22 74.484616008356 1-nm-pp1 PP1 Analog II inhibitors inhibits inhibition kinases mutated analogs sensitive v-Src vSrc c-Fyn cFyn CDK2 CAMKII mammalian yeast 1NMPP1 74.484616008356
13373 2',3',5'-triacetyl-5-Azacytidine 10302-78-0 ≥95% 2010-08-05 7.381182834382 2-3-5-triacetyl-5-azacytidine inhibitors inhibits inhibition DNA methyltransferases epigenetics methylation myelodysplastic syndromes cancers prodrugs 5-azacytidine 5-azacitidine vidaza azacytidine azacitidine rapid absorption o rally 7.381182834382
10011048 2,3-dihydrothieno-Thiadiazole Carboxylate - ≥98% 2008-12-14 0.112338858195 2-3-dihydrothieno-thiadiazole-carboxylate MTCC inhibitors inhibits inhibition CYP450 thiadiazoles cytochromes 0.112338858195
71200 2,4-DPD 41438-38-4 ≥98% 57.398581952118 2-4-dpd 2,4-Diethylpyridine dicarboxylate inhibits inhibition inhibitors proline-hydroxylases P564 HIF-PH HIF-1alpha HIF-1.alpha. alpha-keto glutarate .alpha.-keto a-keto cancer 57.398581952118
13222 2-Acetyl-5-tetrahydroxybutyl Imidazole 94944-70-4 ≥95% 2009-10-08 58.696187845304 2-acetyl-5-tetrahydroxybutyl-imidazole THI; 2-ATHBI; 2-Acetyl-4-tetrahydroxybutyl Imidazole sphingosines-1-phosphates S1P lyases S1PL inhibitors lymphatic tissues lymphocytes egress thymus lymphoid organs lymphopenia immunosuppression 58.696187845304
10007121 2-cyano-Pyrimidine 14080-23-0 >98% 2006-06-19 1.787375690607 2-cyano-pyrimidine Bridge organics inhibits inhibition inhibitors cathepsin K osteoporosis bone resorption osteoclasts lysosomes cysteine proteases 1.787375690607
10010494 2-PCPA (hydrochloride) - >98% 2008-05-09 0.453985793211 2-pcpa-hydrochloride trans-2-Phenylcyclopropylamine; Tranylcypromine 2 PCPA 2PCPA LSD1 histones chromatin nucleosomes post-translational modifications posttranslational methylation demethylation inhibitors inhibits inhibition MAO A B I MAOA MAOB MAOI MAO-A MAO-B MAO-I depression anxiety parkinsons disease epigenetics monoamine oxidases lysine-specific demethylase 0.453985793211
10727 3,5-dimethyl PIT-1 701947-53-7 ≥98% 2011-05-25 16.321319828115 3-5-dimethyl-pit-1 PIP3 PtdIns-(3,4,5)-P3 PH domain cancers inhibitors Akts PDK1 PTENs proteins binding inhibits inhibited inhibition DM-PIT-1 16.321319828115
10397 3-amino Benzamide New 3544-24-9 ≥98% 2011-10-07 2.289024419063 3-amino-benzamide 3-(Aminocarbonyl) Aniline; 3-Carboxamidoaniline poly(ADP-ribose) polymerases PARPs DNA repairs DNA strands breaks apoptosis inflammation atherosclerosis neruogenesis cancers angiogenesis signaling cellular responses inhibits inhibitor inhibition telomere shortening shortens stimulates mediated mediates PARP-mediated 2.289024419063
13574 3-bromo-5-phenyl Salicylic Acid Exclusive 4906-68-7 ≥95% ✓ 2010-08-10 12.693193370165 3-bromo-5-phenyl-salicylic-acid NSC 109116 Aldo-keto reductases AKR, oxidoreductases hydroxysteroid dehydrogenases HSDs 20α-HSD progesterones cancers steroids brain functions AKR1C1 AKR1C2 AKR1C3 AKR1C4 endothelial cells 12.693193370165
9000786 3-Deaza-2'-deoxyadenosine 78582-17-9 ≥98% 2011-06-15 53.081187845303 3-deaza-2-deoxyadenosine c3dA inhibitors genes regulation immunology lymphocytes cytolysis nucleosides adenine nitrogen DNA 53.081187845303
9000785 3-Deazaadenosine 6736-58-9 ≥98% 2011-06-14 0.693370165745 3-deazaadenosine c3Ado; deaza-Ado; DZA S-adenosylhomocysteine hydrolases homocysteine S-adenosylmethionine methyltransferases inhibitors SAH anti-inflammatory NF-κB NF κB NF kB anti-viral anti-bacterial inflammation infectious diseases leukocytes chemotaxis lymphocyte-mediated cytolysis phagocytosis degranulation signaling 3-DZA ado inhibits inhibition SAM 0.693370165745
13828 3-Deazaneplanocin A 102052-95-9 ≥98% 2011-02-18 209.440418310971 3-deazaneplanocin-a DZNep; NSC 617989 EZH2 KMT6 methyltransferases histones cancer epigenetics panobinostat 3deazaneplanocin 3-cyclopentene-1,2-diol deriv Adenosine Adenocard 209.440418310971
10011040 4,5-diphenyl-1,2,3-Thiadiazole 5393-99-7 ≥98% 2008-11-15 0.337016574586 4-5-diphenyl-1-2-3-thiadiazole NSC 2505 thiadiazoles inhibitors inhibits inhibition CYP450 4,5-diphenylthiazole enzymes cytochrome 0.337016574586
10495 4-iodo-SAHA 1219807-87-0 ≥98% 2011-01-10 30.252121546961 4-iodo-saha anti-cancers HDACs inhibitors anti-proliferation 4-Hydroxy-5-iodo-3-nitrophenyl)acetyl 4-Hydroxy-3-iodo-5-nitrophenyl)acetyl 5-Iodo-4-hydroxy-3-nitrophenacetyl 5 Iodo 4 hydroxy 3 nitrophenacetyl Nitrohydroxyiodophenylacetate Hydroxyiodonitrophenylacetate Hapten NIP Acetyl Acetyl Hapten NIP NIP Acetyl Hapten NIP-Hapten NIP Hapten 30.252121546961
13140 4-(n-nonyl) Benzeneboronic Acid 256383-45-6 ≥98% 2009-11-04 6.668687845304 4-n-nonyl-benzeneboronic-acid fatty acids amide hydrolase FAAH endocannabinoids arachidonoyl ethanolamides AEA inhibitors inhibit monoacylglycerol lipase MAGL 2-arachidonoyl glycerol 2-AG 2AG 2 AG inhibition cannabinoids cbs synthetic 6.668687845304
10011049 4-phenyl-5-methyl-1,2,3-Thiadiazole 64273-28-5 ≥98% 2009-03-14 0.168508287293 4-phenyl-5-methyl-1-2-3-thiadiazole NSC 358739 cytochrome P450 CYP450 CYP2B4 CYP2E1 CYP1A2 inhibitors inhibits inhibition thiadiazoles fungicide herbicide plant growth regulator 0.168508287293
90200 5,8,11-Eicosatriynoic Acid 13488-22-7 ≥99% 14.012469613259 5-8-11-eicosatriynoic-acid 5,8,11-ETI acetylene inhibitors lipoxygenase cyclooxygenase fatty acids 14.012469613259
70265 5-Aminosalicylic Acid 89-57-6 >99% 2.050757695343 5-aminosalicylic-acid 5-ASA aspirin 5asa acids COX-1 COX-2 cox1 cox2 cyclooxygenases prostaglandin synthases synthase-1 synthase-2 pghs1 pghs2 pghs-1 pghs-2 ltb4 leukotriene 2.050757695343
13379 5-bromo-3-phenyl Salicylic Acid 99514-99-5 ≥95% 2010-08-10 12.659381215469 5-bromo-3-phenyl-salicylic-acid Aldo-keto reductases AKR oxidoreductases hydroxysteroid dehydrogenases HSD 20α-HSD progesterone cancers steroids brain functions AKR1C1 AKR1C2 AKR1C3 AKR1C4 endothelial cells 12.659381215469
34215 (±)5-HETE lactone 73279-37-5 ≥98% 7.763629834254 -5-hete-lactone racemic hydroxy acids lactones autoxidation (+/-)5-HETEs fatty (+/-)-HETEs (+/-)HETEs inhibitors inhibits 5-LOs 5-lipoxygenases 7.763629834254
10010375 5-Iodotubercidin 24386-93-4 ≥95% 2008-01-24 40.749410681400 5-iodotubercidin Itu; NSC 113939 adensosine glycogen hepatocytes phosphorylase .alpha. glycogen synthase .alpha. kinases protein kinase A casein kinases II casein kinases I protein kinase C phosphorylase kinases EFK2 MAPK1 cell proliferations fatty acid oxidations lipogenesis acetyl-CoA carboxylase 40.749410681400
10009598 6,7-dihydroxy Bergamottin 145414-76-2 >98% 2007-07-24 5.001171270718 6-7-dihydroxy-bergamottin 6,7-DHB cytochrome P450 CYP3a4 inhibitors inhibits inhibition grapefruit juice testosterone ingestion drugs metabolized metabolite metabolism stereochemistry endocrinology 5.001171270718
81040 6,7-Dimethyltetrahydropterin (hydrochloride) 167423-51-0 ≥99% 8.336003683241 6-7-dimethyltetrahydropterin-hydrochloride GTP cyclohydrolase inhibitors inhibits 8.336003683241
10009315 6-Aminonicotinamide 329-89-5 ≥98% 2008-11-21 2.086464088398 6-aminonicotinamide 6-AN; NSC 21206; SR 4388 inhibitors inhibits inhibition 6-phosphoguconate dehydrogenase cancers ATPs oxidative injury neurodegeneration cardiovascular 2.086464088398
70620 6-methoxy Naphthalene Acetic Acid 23981-47-7 >99% 21.536888888888 6-methoxy-naphthalene-acetic-acid 6-MNA cyclooxygenases inhibitors NSAIDs COX-1 COX-2 nonsteroidal anti-inflammatory drugs cox1 cox2 pghs1 pghs2 pghs-1 pghs-2 prostaglandin H synthases synthase-1 synthase-2 inhibits 21.536888888888
81882 7,8-dihydro-L-Biopterin 6779-87-9 >97% 23.265566298342 7-8-dihydro-l-biopterin Dihydrobiopterin; BH2 GTP cyclohydrolase inhibitors tetrahydrobiopterin 23.265566298342
10007900 8,11,14-Eicosatriynoic Acid Exclusive 34262-64-1 ≥98% ✓ 2007-03-12 0E-12 8-11-14-eicosatriynoic-acid 8,11,14-ETI Cyclooxygenases COX 12-LO 15-LO 5-LO Inhibitor Fatty acids Acetylenic Lipoxygenases SRS-A FA 0E-12
90100 8,11-Eicosadiynoic Acid 82073-91-4 ≥95% 2.692099447514 8-11-eicosadiynoic-acid EDYA acetylene inhibitors delta-5-desaturase cyclooxygenases .DELTA.-5-desaturase D-5-desaturase inhibits fatty acids D5-desaturase 2.692099447514
89300 8-hydroxy Guanosine - ≥98% 8.885138121547 8-hydroxy-guanosine oxidative injury RNA stress damage 7,8-dihydro-8-oxo-guanosine markers inhibitors growth 3868-31-3 8.885138121547
10012708 A-922500 959122-11-3 ≥95% 2010-12-21 258.460724370779 a-922500 (1R,2R)-2-(4'-(3-phenylureido)biphenylcarbonyl)-cyclopentanecarboxylic acid triglyceride obesity insulin resistance inhibitors metabolic syndrome diacyl glycerolacyltransferase DGAT-1 DGAT1 DGAT 1inhibits inhibition A-922500 A922500 mice murine diet induced obesity DIO diet-induced Compounds, Biphenyl Biphenyl Compounds 258.460724370779
13649 Abacavir (hydrochloride) 136777-48-5 ≥98% 2010-08-17 19.725759668508 abacavir-hydrochloride carbovirs triphosphates inhibitors inhibits inhibition HIV reverses transcriptases AIDS sulphates HCl 1592 U89 1592-U89 human bones marrow progenition cells blood-brain barrier 2',3'-Dideoxy-3'-thiacytidine 2',3' Dideoxy 3' thiacytidine Lamivudine, (2S-cis)-Isomer 2',3'-Dideoxynucleosides 2',3' Dideoxynucleosides Dideoxyribonucleosides Dideoxynucleosides Lamivudine GR-109714X GR109714X BCH-189 BCH 189 EpivirBCH189 ddNus 3TC ziagen 188062-50-2 1592U89 19.725759668508
13653 ABT-869 796967-16-3 ≥98% 2010-12-09 33.831887966046 abt-869 Linifanib inhibitors RTK tyrosine kinases VEGF PDGF cancers KDR Flt1 Flt3 Flt4 CSF-1R KIT acute myeloid leukemia antiproliferative anti-proliferative ABT 869 ABT869 Indazoles 33.831887966046
13297 AG-126 118409-62-4 ≥95% 2009-07-14 6.085153906866 ag-126 Tyrphostin AG-126 tyrphostins proteins tyrosine inhibitors inhibits inhibition cells growth epidermal growth factors receptors kinase GFRK EGFs EGFRK PDGF PDGFRK platelet-derived platelet derived phosphorylation ERK1 p44 ERK2 p42 TNF-α TNFα TNF α NF-κB NFκB NF κB COX-2 COX2 iNOS inflammation 6.085153906866
10010592 AG-1296 146535-11-7 >98% 2008-05-09 5.001425414364 ag-1296 Tyrphostin AG-1296 tyrphostins AG1296 PDGFR PTK SCF inhibitors inhibits inhibition receptors kinases proteins platelet-derived platelet derived growth factors in vitro cancer glioma athrosclerosis restenosis AG1296 AG 1296 5.001425414364
10010244 AG-1478 153436-53-4 >98% 2008-04-22 9.154342541435 ag-1478 NSC 693255; Tyrphostin AG-1478 NSC 693255 EGFR PTK inhibitors inhibits inhibition kinases receptors cancers antitumor leioyoma myometrium 175178-82-2 AG1478 AG 1478 9.154342541435
10010248 AG-17 10537-47-0 ≥98% 2007-09-18 1.703761155971 ag-17 NSC 242557; RG-50872; GCP 5126; SF 6847; Tyrphostin AG-17; Malonoben; Tyrphostin 9 proteins tyrosine kinases PTK inhibitors inhibits antiproliferative epidermal growth factor EGF receptors proliferations carcinomas AG17 AG 17 SF6847 SF-6847 GCP-5126 GCP5126 1.703761155971
10010300 AG-18 118409-57-7 >98% 2007-12-20 2.417794305142 ag-18 RG-50810; Tyrphostin AG-18; Tyrphostin 23; TX 825; RG-50858 proteins tyrosines kinases PTKs inhibitors inhibition inhibits antiproliferative epidermal growth factors EGF receptors proliferations carcinoma cancers epidermoid cell lines A431 AG18 AG 18 A23 A-23 A23 RG50810 RG 50810 RG50858 RG 50858 TX-825 TX825 2.417794305142
10010315 AG-183 122520-90-5 >98% 2007-09-07 1.435570902393 ag-183 Tyrphostin 51 proteins tyrosine kinases PTKs inhibitors inhibition inhibits inhibition antiproliferative epidermal growth factors EGFs receptors proliferation carcinomas cancers epidermoid AG183 AG 183 1.435570902393
10010314 AG-213 122520-86-9 >97% 2008-02-05 2.375052737317 ag-213 Tyrphostin AG-213; Tyrphostin 47 protein tyrosine kinases PTKs inhibitors inhibits inhibition antiproliferative epidermal growth factors EGFs receptors proliferation carcinomas A431 epidermal AG213 Ag 213 118409-60-2 2.375052737317
10010568 AG-370 134036-53-6 >95% (cis/trans mixture) 2009-01-09 1.265759668508 ag-370 NSC 651712 PTK inhibitor tyrphostin tyrosine PDGF receptor kinase EGF receptor antiproliferative 1.265759668508
10010311 AG-490 133550-30-8 >98% 2007-12-01 9.933476058931 ag-490 PTK tyrosine kinase inhibitors inhibition inhibits antiproliferatives tyrphostins leukemia Jak-2 Jak2 AG490 9.933476058931
10010242 AG-494 133550-35-3 >98% 2008-02-08 1.845741252301 ag-494 protein tyrosine kinases PTKs inhibitors inhibits inhibition antiproliferative RG-13022 epidermal growth factors EGFs receptrors cancers proliferation 1.845741252301
10010312 AG-82 118409-58-8 >95% 2008-03-14 4.223517495395 ag-82 Tyrphostin AG-82; NSC 676484; RG-50875; Tyrphostin 25 proteins tyrosines kinases PTKs inhibitors inhibits inhibition antiproliferative epidermal growth factors EGFs receptors proliferation carcinomas blockers A431 AG82 AG 82 RG-50875 RG50875 A25 A-25 4.223517495395
10010243 AG-825 149092-50-2 >98% 2008-01-24 4.725808997632 ag-825 Tyrphostin AG-825 Her-2 Her-2/neu erbB tyrosine kinases EGF EGFR cancers anti-cancer prostate breast signal transduction inhibitors inhibition inhibits AG825 AG 825 4.725808997632
10793 AG-879 148741-30-4 ≥95% 2011-05-06 1.809287292817 ag-879 Tyrphostin AG-879 PTKs inhibitors tyrphostins tyrosine kinases antiproliferative NGF TrkA ErbB2 FLK-1 AG879 AG 879 inhibited inhibition 1.809287292817
10010313 AG-99 122520-85-8 >98% 2007-12-19 1.273508287292 ag-99 Tyrphostin 46 protein tyrosine kinase PTKs inhibitor inhibits inhibition antiproliferatives epidermal growth factors EGFs receptors proliferation carcinoma cancers blochers EGF-dependent A431 cell lines AG99 AG 99 1.273508287292
13145 AGK2 304896-28-4 ≥98% 2009-10-22 12.525055248618 agk2 sirtuins SIRT2 histones deacetylase HDAC cells cycle progression tumorigenesis cancers SIRT1 SIRT3 dopamine neurons α-synuclein Parkinson's diseases neurodegeneration 12.525055248618
13642 Alendronate (sodium hydrate) 121268-17-5 ≥95% 2010-08-02 30.909539594843 alendronate-sodium-hydrate MK-217; G-704650; Fosamax; Adronat Bisphosphonates bones resorption osteoclasts osteoblasts osteoporosis bone mineral density fractures metabolic diseases vertebral fractures increase decreases 4-Amino-1-Hydroxybutylidene 1,1-Biphosphonate 4 Amino 1 Hydroxybutylidene 1,1 Biphosphonate Bisphosphonate Aminohydroxybutane Alendronate Monosodium Trihydrate Aminohydroxybutane Bisphosphonate Sodium Alendronate Alendronate Sodium Alendronate Fosamax MK-217 MK 217 MK217 30.909539594843
13648 Alfuzosin (hydrochloride) 81403-68-1 ≥98% 2010-07-19 0.603038674033 alfuzosin-hydrochloride Uroxatral; SL 77499-10 α1-adrenergic receptors antagonists lower urinary tract symptoms benign prostatic hyperplasia BPH adrenoceptors α1A α1B α1D contractions smooth muscles antihypertensives vasodilators urinary flow 133880-44-1 Urion Alfoten SL 77-499-10 anti-hypertensives alpha 1 .alpha.1 Xatral Quinazolines 0.603038674033
10012597 Allopurinol 315-30-0 ≥98% 2009-12-07 22.387734806630 allopurinol xanthine oxidoreductase oxidation hypoxanthine uric acids dehydrogenases oxidases superoxides inhibitors inhibition inhibits gout hyperuricemia oxypuriol 22.387734806630
11306 Alternariol New 641-38-3 ≥98% 2012-01-31 137.038795580110 alternariol AOH; NSC 638263 11003-13-7 fungus molds mycotoxins toxins metabolites Alternaria CYP450 cytochromes P450 1A1 cytotoxin fetotoxin teratogenic mutagenic genotoxin apoptosis hepatoma cells 641-38-3 AC1NSEOY A1312 ZINC00402623 NSC-638263 NSC638263 CCRIS6734 CCRIS-6734 NCGC00180653-01 LS61189 LS-61189 LS 61189 NP001789 NP-001789 NP 001789 C16838 C-16838 C 16838 5-18-04-00516 BRD-K62196712-001-01-3 137.038795580110
10010332 AMP-Deoxynojirimycin Exclusive 216758-20-2 ≥95% ✓ 2008-11-21 28.911821158175 amp-deoxynojirimycin Adamantane-pentyl-dNM; N-(5-adamantane-1-yl-methoxy-pentyl)-Deoxynojirimycin; AMP-dNM inhibitors inhibits inhibition ceramides lipids glycolipids glucosylceramide synthase glucosylceramidase β-glucosidase 2 glucosidase sphingomyelin deoxynorjirimycin nojirimycin inflammation antiinflammatory anit-inflammatory hapten colitis insulin sensitivity resistance SREBPs sterol genes expression cholesterol HepG2 cells 28.911821158175
13144 Anacardic Acid 16611-84-0 ≥98% 2010-02-12 3.763515709289 anacardic-acid 6-pentadecyl Salicylic Acid HAT histones acetylation P300 pCAF transcription NF-κB IκBα p65 6-pentadecyl salicyclic acids NSC 623096 cyclogallipharic 229596 333857 3.763515709289
11001 Anatabine New 2743-90-0 ≥95% 2011-11-10 0.311827956989 anatabine alkaloids solanaceae tobacco Alzheimer’s diseases amyloid beta Aβ β-secretase BACE-1 NF-κB inflammation urine nicotine transcription proteins SHSY-5Y cells 0.311827956989
10575 Apicidin New 183506-66-3 ≥98% 2012-01-27 106.538339472068 apicidin OSI 2040 funfal toxins malaria HDAC HAT histones deacetylase transcriptions epigenetics anticancer anti-cancer antiproliferation antiparasitic anti-proliferation anti-parasitic apicomplexan parasites HDAC3 HDAC-3 NcoR HDAC3/NcoR class I HDACs p21 WAF1/Cip1 WAF1 Cip1 gelsolin cells cycle morphology inhibits inhibitors inhibitions chromatin cancers deacetylase modification 106.538339472068
10010275 Apigenin 520-36-5 >98% 2008-02-18 152.469861878452 apigenin Versulin; NSC 83244; Flavone; Chamomile flavonoids flavones CK2 inhibitors inhibits inhibition inflammatory response anti-inflammatory anti-oxidant NO PGE2 iNOS COX-2 I.kappa.B.alpha. NF-.kappa.-B renal cortex 152.469861878452
90050 Arachidonoyl Ethanolamide 94421-68-8 ≥98% 35.180919814842 arachidonoyl-ethanolamide Anandamide; AEA cannabinoids neurotransmitter ligands lipids CB1 CB2 receptors AEA fatty acids neuroscience neurochemistry ethanolamines ethanolamides endocrinology 35.180919814842
10007270 Arachidonoyl Ethanolamide Lipid Maps MS Standard 94421-68-8 ≥98% 2009-02-18 6.314611134721 arachidonoyl-ethanolamide-lipid-maps-ms-standard AEA; Anandamide cannabinoids neurotransmitter ligands lipids CB1 CB2 receptors AEA fatty acids neuroscience neurochemistry ethanolamines ethanolamides endocrinology MS mass spectrometry standards 6.314611134721
13321 ARP 100 704888-90-4 ≥98% 2009-10-07 1.460589318600 arp-100 MMP-2 Inhibitor III; CAY10609 matrix metalloproteinases MMP-2 MMP2 MMP 2 ECM cancers cells migration inhibitors gelatinase A MMPs proteases HT1080 tumors invasive 1.460589318600
13622 AS-041164 Exclusive 1146702-72-8 ≥98% ✓ 2010-01-25 12.284825046040 as-041164 phosphoinositides 3-kinases PI3K cells growth migration metabolism inhibitors inhibits PI3Kα PI3Kβ PI3Kγ PI3Kδ chemotaxis inflammation neutrophils AS041164 AS-041164 RANTES 12.284825046040
13250 (−)-AS 115 926657-43-4 ≥98% 2009-05-18 4.425230202578 -as-115 KIAA1363 MAGE monoacylglycerol LPA LPC lysophosphatidylcholine lysophosphatidic acid lipids signaling cancers signalling 4.425230202578
10009650 (+)-AS 115 - ≥98% 2009-05-19 2.409834254143 -as-115 KIAA1363 MAGE monoacylglycerol LPA LPC lysophosphatidylcholine lysophosphatidic acid lipids signaling cancer 2.409834254143
10010175 AS-604850 Exclusive 648449-76-7 >98% ✓ 2007-07-23 15.371733425414 as-604850 phosphoinositides 3-kinases PI3-kinase PI3-K phosphatidylinositol inflammatory drugs inflammation arthritis rheumatoid peritonitis neutrophils recruitment PtdIns inhibitors inhibits inhibiton PI3K 15.371733425414
10007707 AS-605240 648450-29-7 >98% 2007-06-13 27.564988950276 as-605240 phosphoinositide 3-kinases PI3-kinase PI3-K PI3K phosphoinositide phosphatidylinositols inibitors inflammation arthritis rheumatoid peritonitis neutrophils recruitment as605240 27.564988950276
9000980 AS-605240 (potassium salt) Exclusive - ≥98% ✓ 2011-03-25 20.803078137332 as-605240-potassium-salt phosphoinositides 3-kinases PI3-kinases PI3-K PI3K phosphatidylinositols inhibitors inflammation arthritis rheumatoid peritonitis neutrophils recruitment as605240 as 605240 PIs salts solubility soluble 20.803078137332
70260 Aspirin 50-78-2 >99% 10.936541659691 aspirin Acetylsalicylic Acid atherosclerosis cyclooxygenases inhibitors NSAIDs COX-1 COX-2 nonsteroidal anti-inflammatory drugs cox1 cox2 pghs1 pghs2 pghs-1 pghs-2 prostaglandin H synthases synthase-1 synthase-2 inhibits 10.936541659691
13160 AT-56 Exclusive 162640-98-4 ≥95% ✓ 2010-06-22 14.424548802946 at-56 Prostaglandins D synthases L-PGDS PGD2 lipocalin-type inflammation inhibition inhibitors inhibits PGs eosinophils LPGDs bronchoalveolar lavage fluid Lysosomal Proton Translocating ATPases Vacuolar Proton-Translocating ATPases Vacuolar Membrane H(+)-ATPase Proteins Membrane-Associated Membrane-Associated Proteins Membrane Associated Proteins Tacrolimus Binding Proteins Proteins Rapamycin-Binding Proteins Integral Membrane Membrane Proteins Integral Binding Proteins Rapamycin Rapamycin-Binding Proteins Rapamycin Binding Proteins Protein Integral Membrane Integral Membrane Proteins Vacuolar F(1)F(0) ATPasesLysosomal F(1)F(0) ATPase Integral Membrane Protein Vacuolar F(1)F(0) ATPase Proteins Cell Membrane Protein FK-506-Binding Proteins Cell Surface Protein FK506-Binding FK-506-Binding ProteinFK506 Binding Proteins FK 506 Binding Protein Cell Membrane Proteins FK506-Binding ProteinFK506 Binding Protein Cell Surface Proteins H+-ATPase, Vacuolar Vacuolar H+-ATPase Vacuolar H+ ATPase Proteins Membrane Proteins Vacuolar ATPase Rotamase FKBP V Type ATPase FKBP Rotamase Membrane FKBP 14.424548802946
13375 Atrazine 1912-24-9 ≥98% 2010-02-11 0.182320441989 atrazine herbicides plants cancers reproductive systems reproduction homones endocrines frogs genes expressions humans animals Gesamprim Atrazine 0.182320441989
10011336 Avenanthramide-C methyl ester Exclusive 955382-52-2 ≥95% ✓ 2009-06-18 68.208076343546 avenanthramide-c-methyl-ester Inhibitors NF-κB IL-6 IL-8 MCP-1 IκB inhibits inhibition Interleukins 68.208076343546
13823 AX 048 Exclusive 873079-69-7 ≥98% ✓ 2010-09-15 9.193425414365 ax-048 Inflammation antihyperalgesia cPLA2 phospholipases inhibitors inhibition inhibits AX048 AX-048 signaling signalling group IVA PLA2 cannabinoids cbs synthetic Acids Octanoic Octanoic Acids 9.193425414365
10010266 BAY-11-7082 19542-67-7 ≥98% 2008-07-25 29.500721085946 bay-11-7082 inhibitors inhibits inhibition NFkB NF-.kappa.B NF-kB NF-kappaB TNF.alpha. TNFa TNFalpha I.kappa.B-.alpha. IkB-a IkappaB-alpha inflammation cytokine cell adhesion ICAM-1 ICAM1 VCAM-1 VCAM1 E-selection Eselection Bay 11-7082 BAY-117821 Bay117082 BAY 117821 29.500721085946
10009644 BAY-43-9006 New 284461-73-0 ≥98% 2011-09-13 30.859047876037 bay-43-9006 Sorafenib; Nexovar® inhibitors raf-1 b-raf receptors tyrosine kinases VEGF VEGFR PDGF PDGFR cancers angiogenesis apoptosis tumors cells cellular proliferation Flt-3 c-KIT carcinoma growth factor tosylate 30.859047876037
10011135 BAY-60-7550 439083-90-6 ≥95% 2009-03-13 62.156844151329 bay-60-7550 inhibitors inhibits inhibition cyclic nucleotides cGMP cAMP cells signalling signaling PDE2 memory memories phosphodiesterase 62.156844151329
10170 BEC 63107-40-4 >98% 2006-02-15 25.488895027624 bec inhibitors L-arginases I II substrates nitric oxides synthases iNOS cells catalyzes oxidations citrullines N.omega.-hydroxy-L-arginine NOHA intermediates hydrolysis urea L-ornithine recombinant rat livers human inhibits murine NO-dependent relaxation penile corpus cavernosum smooth muscle in vitro 25.488895027624
70520 Bestatin (hydrochloride) 65391-42-6 >99% 121.615193370166 bestatin-hydrochloride LTA4 hydrolase inhibitors leukotrienes LTB4 121.615193370166
10010517 BIBB 515 156635-05-1 ≥98% 2008-06-16 1.130552486188 bibb-515 inhibitor inhibits inhibition BIBB515 OSC LDL 2,3-oxidosqualene cyclase cholesterol BIBB-515 1.130552486188
11022 BIBF 1120 New 928326-83-4 ≥95% 2011-11-10 3.673118279570 bibf-1120 Vargatef™ receptors tyrosine kinases inhibitors vascular endothelial growth factor VEGFR platelet-derived growth PDGFR fibroblasts FGFR angiogenesis cancers pulmonary fibrosis diseases 3.673118279570
13123 BIO 667463-62-9 ≥98% 2009-06-09 30.261531893520 bio GSK 3 IX; MLS 2052 GSK-3α GSK-3β inhibitors Cdk cells cycle wnt ESCs differentiation embryonic stem GSK-3a/b GSK3a/b 30.261531893520
10960 Bisdemethoxycurcumin 24939-16-0 ≥98% 2011-08-09 5.449443726081 bisdemethoxycurcumin BDMC curcumin activators macrophages phagocytosis 1α,25-dihydroxyvitamin D, amyloid-β Alzheimer’s diseases cancers transcription genes expression p300 Wnt/β-catenin iNOS inflammation bisdemethoxy curcumin 33171-05-0 5.449443726081
13298 Bisindolylmaleimide I 133052-90-1 ≥95% 2009-08-28 13.520359116022 bisindolylmaleimide-i Gö 6850; GF 109203X; BIM 634199-82-9 682340-45-0 inhibitors inhibits inhibitions PCK GSK-3 GSK3 staurosporine 5-HT3 receptors 5HT3 Go 6850 13.520359116022
13299 Bisindolylmaleimide IV 119139-23-0 ≥98% 2009-07-29 9.038149171270 bisindolylmaleimide-iv Arcyriarubin A PKC PKA staurosporine inhibitors 634199-73-8 9.038149171270
13124 BIX01294 (hydrochloride hydrate) - ≥98% 2009-12-03 31.303576329171 bix01294-hydrochloride-hydrate euchromatin genes expressions epigenetics G9a histones methyltransferase HMTase embryogenesis imprinting lymphocytes development inhibitors proteins GLP stem cells 935693-62-2 31.303576329171
13013 (−)-Blebbistatin 856925-71-8 ≥98% 2009-04-16 30.649999999999 -blebbistatin (S)-Blebbistatin inhibitors muscles myosin ATPase smooth muscle bleb apoptosis cell migration chemotaxis cytokinesis cells division growth UV light blebs (-)-(S)-Blebbistatin 30.649999999999
13165 (+)-Blebbistatin - ≥98% 2009-04-16 36.576353591160 -blebbistatin (R)-Blebbistatin inhibitors muscles myosin ATPase smooth muscle bleb apoptosis cell migration chemotaxis cytokinesis cells division growth UV light (+)-(R)-Blebbistatin inhibition inhibited 36.576353591160
13186 (±)-Blebbistatin 674289-55-5 ≥98% 2009-06-09 49.568563535911 -blebbistatin inhibitors muscles myosin ATPase smooth bleb apoptosis cells migration chemotaxis cytokinesis division growth UV lights 49.568563535911
10155 BM 567 284464-77-3 >98% 2005-03-31 51.973006445672 bm-567 platelets thromboxanes TXA2 atherosclerosis synthases inhibits inhibition inhibitors antagonists BM567 BM-567 thrombogenic vasocontrictors TP receptors eicosanoids strokes myocardial infarctions GPCR vascular smooth muscles protein-coupled license:liege 51.973006445672
10488 Bupropion (hydrochloride) 31677-93-7 ≥98% 2010-08-16 24.251151406400 bupropion-hydrochloride NSC 315851 34841-36-6 Zyban Wellbatrin inhibitors inhibits inhibition reuptake dopamine norepinephrine Voxra Aplenzin Amfebutamone antagonists neuronal acetylcholine nicotinic receptors nAChR antidepressant depression neurosciences Wellbutrin 1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone GlaxoSmithKline Brand 2 of Bupropion Hydrochloride GlaxoSmithKline Brand 1 of Bupropion Hydrochloride Glaxo Wellcome Brand 3 of Bupropion Hydrochloride Glaxo Wellcome Brand 2 of Bupropion Hydrochloride Glaxo Wellcome Brand 1 of Bupropion Hydrochloride Esteve Brand of Bupropion Hydrochloride Bupropion Hydrochloride Bupropion Hydrochloride Zyban (Anti-Smoking) Amfebutamone Wellbutrin Bupropion Bupropion Zyntabac Quomen Isomer 24.251151406400
13285 Cannabidiol dimethyl ether 1242-67-7 ≥98% 2009-05-19 12.557320441989 cannabidiol-dimethyl-ether Cannabidiol-2',6'-dimethyl ether; CBDD 15-lipoxygenases 15-LOs dioxygenase fatty acids inflammation thrombosis cancer LDL oxidation inhibitions inhibition inhibiting cannabinoids cbs synthetic 12.557320441989
11313 Castanospermine New 79831-76-8 ≥98% 2012-01-31 89.984376918355 castanospermine 6,7-Diepicastanospermine; 6-Epicastanospermine; NSC 625381; 1,6,7,8-Tetrahydroxyoctahydroindolizine inhibitors inhibits inhibition glucosidases glycogen glycosylation glycoproteins complex carbohydrates viruses infections lysosomes angiogenesis proteins cells NSC625381 NSC-625381 BML-S107 BMLS107 BML S107 89.984376918355
70130 CAY10397 78028-01-0 >98% 30.429226519336 cay10397 CK47A inhibitors inhibits 15-hydroxy prostaglandins dehydrogenases 15-OH-PGDH PG15DH 15-hydroxy-PGDH 30.429226519336
70210 CAY10404 - >98% 37.777254869133 cay10404 COX-2 inhibitors PGHS-2 COX2 PGHS2 prostaglandins synthases NSAIDS selective selectivity inhibits inhibition cyclooxygenase 37.777254869133
70635 CAY10416 443919-96-8 >95% 2007-07-24 28.782914364640 cay10416 COX-2 cyclooxygenases 5-LO lipoxygenases inflammation inhibitors prostates cancers PC3 LNCaP carcinomas apoptosis inhibition inhibits chemotherapy cells lines 28.782914364640
10008657 CAY10502 Exclusive - >98% ✓ 2007-08-02 2.664198895028 cay10502 cPLA2.alpha. phospholipases inflammation inhibitors inhibits inhibition arthritis inhibitory cPLA2 AA arachidonic inflammatory inflammation 3-methyl hydrogen 1-[3-(4-decyloxy phenoxy)-2-oxopropyl] indole-3,5 dicarboxylate 2.664198895028
10009078 CAY10505 328960-84-5 ≥98% 2009-11-04 8.324254143646 cay10505 phosphoinositide 3-kinase immunity autoimmune inflammation PI3Kγ PI3Kα PI3Kβ PI3Kδ casein kinases 2 CK2 phosphorylation PKB/Akt macrophages neutrophil recruitment cancer PI3s T2Ds PI3Ks PI3K.gamma. PI3Kg 8.324254143646
10010088 CAY10526 Exclusive 938069-71-7 >98% ✓ 2007-09-07 352.918618784530 cay10526 mPGES-1 mPGES1 microsomal prostaglandin E2 PGE2 synthase prostanoid modulators inflammatory inflammation pain inhibition inhibitors inhibits expressions 352.918618784530
10010740 CAY10550 34320-83-7 ≥98% 2008-07-14 5.031674723756 cay10550 3-(4-Nitrophenyl)-1-phenyl-2-pyrazolin-5-one prion PrPc PrPsc PrPres mad cow disease scrapie creutzfeldt-jakob disease spongigorm encephalopathy radical scavenger inhibitors inhibits inhibition 5.031674723756
10010301 CAY10554 267654-00-2 >95% 2007-12-01 8.847974217311 cay10554 BML-259 cell cycle cdk5 cdk2 inhibitors inhibits inhibition cancers BML 259 BML259 CDKs neurodegenerative diseases 8.847974217311
10010043 CAY10561 Exclusive 933786-58-4 >98% ✓ 2008-03-06 27.155911602210 cay10561 Pyrazolylpyrrole ERK Inhibitor MEK Ras Raf ERK2 proliferation cell cycles cancers apoptosis inhibition inhibit inhibitors 27.155911602210
10012562 CAY10566 944808-88-2 ≥98% 2009-01-07 48.417679558011 cay10566 SCD1 long chain fatty acids monounsaturated type 2 two diabetes dyslipidemia obesity 48.417679558011
10010233 CAY10567 32387-96-5 >98% 2008-05-06 3.311602209944 cay10567 BML-257 Akt1 inhibitors inhibits inhibition translocations HCV hepatitis signal transduction signaling signalling 3.311602209944
10010032 CAY10570 Exclusive 875014-22-5 >98% ✓ 2008-06-03 16.145870165746 cay10570 FAAH fatty acids amides AEA anandamides CB1 inhibitors inhibits inhibition endocannabinoids hydrolases cannabinoids 16.145870165746
10010400 CAY10571 152121-46-5 >95% 2008-08-11 21.845082872929 cay10571 MAPK signal transduction p38 kinases heat shock cytokines inflammation immuno response CSAID CSBP UL-1 IL1 5-LO 5LO 21.845082872929
18218 CAY10572 845714-00-3 ≥98% 2009-03-02 11.357182320442 cay10572 PHA 767491 inhibits inhibition inhibitors cdc7 kinases pyrrolopyridinone DNA synthesis cells death cycles apoptosis p53 cancers cdk9 antitumor agents anti-tumor 11.357182320442
10011247 CAY10574 140651-18-9 >95% 2008-09-04 12.652707182320 cay10574 CDK2 cyclin E CDK9 inhibitors inhibits inhibition anticancer cell cycle CAN508 12.652707182320
10011248 CAY10575 916985-21-2 ≥95% 2008-09-03 28.167048145225 cay10575 IKKε IKK-ε IKK-e IKKe NFkB inflammation immune response cytokine kinase inhibitors inhibits inhibition NF-κB 28.167048145225
10011249 CAY10576 862812-98-4 ≥95% 2008-09-08 34.836049723757 cay10576 IKK-.epsilon. IKK.epsilon. IKK-epsilon IKK-e IKKe NFkB inflammation immune response cytokine kinase inhibitors inhibits inhibition 34.836049723757
10011256 CAY10577 300675-28-9 ≥95% 2008-09-02 0.867403314917 cay10577 inhibitors inhibits inhibition CK2 kinase cell signaling apoptosis cancers 0.867403314917
10011264 CAY10578 19231-60-8 ≥95% 2008-08-26 0.867403314917 cay10578 inhibitors inhibits inhibition kinase cell signaling CK2 apoptosis cancers isoindolineacetic acids 0.867403314917
16838 CAY10581 Exclusive 1018340-07-2 ≥97% ✓ 2009-05-08 2.949171270718 cay10581 indoleamine 2,3-dioxygenase IDO cancers inhibitors tumors inhibition inhibited naphthoquinones 2.949171270718
13164 CAY10589 Exclusive 1077626-52-8 ≥98% ✓ 2009-06-23 1.657500000000 cay10589 Microsomal prostaglandin E2 synthase-1 mPGES-1 inhibitors cyclooxygenase cyclooxygenase-2 COX-2 PGE2 5-lipoxygenase 5-LO COX-1 leukotrienes LTB4 LTC4 LTD4 LTE4 dual inhibits inhibition inflammation fever pain signaling sagnalling 1.657500000000
13181 CAY10590 Exclusive 1101136-50-8 ≥98% ✓ 2009-04-15 15.854451460142 cay10590 sPLA2 cPLA2 iPLA2 phospholipases inhibitors R-gamma-nonleucine inhibition inhibited secreetory regulates phagocytosis foam cells 15.854451460142
13206 CAY10593 Exclusive - ≥95% ✓ 2009-09-03 20.577944751381 cay10593 VU0155069 inhibitors inhibits inhibitions phospholipases D PLD PLD1 PLD2 phosphatidic acids PAs chemotaxis cells migration cancers breast lines tumors trans well assays 1130067-06-9 20.577944751381
13207 CAY10594 Exclusive 1130067-34-3 ≥98% ✓ 2009-06-23 20.973812154696 cay10594 Phospholipase D PLDs PLD1 PLD2 phosphatidic acid PA inhibitors chemotaxis cells migration cancers breast cancer inhibition inhibited 20.973812154696
13381 CAY10606 1159576-98-3 ≥98% 2009-12-04 92.519167713700 cay10606 5-lipoxygenases 5-LOs leukotrienes LTs LTB4 arachidonic acids inhibitors inhibit neutrophils blood ionophore A23187 formyl peptides fMLP lipopolysaccharides LPS reversed pleurisy inflammation inflammatory inhibition 92.519167713700
10012694 CAY10607 Exclusive 1012788-65-6 ≥98% ✓ 2009-07-07 1.196869244935 cay10607 Benzisoxazole Hsp90 Inhibitor; BHI inhibitors inhibits inhibition heat shocks proteins cancers cells proliferation geldanamycin chaperones 1.196869244935
13358 CAY10608 Exclusive 457897-92-6 ≥98% ✓ 2010-04-29 0.652624309392 cay10608 N-Methyl-D-aspartate NMDA receptors antagonists glutamate glycine propanolamine NR2B subunit AMPA kainate neuroprotection neurochemistry antagonizes potently selectively non-competitively 0.652624309392
13615 CAY10614 Exclusive 1202208-36-3 ≥98% ✓ 2010-03-22 10.774060773481 cay10614 1115270-65-9 Lipids A endotoxins lipopolysaccharides LPS gram-negative bacterias infections toll-like receptor 4 TLR4 immune responses antagonists sepsis inflammation 10.774060773481
13291 CAY10616 Exclusive 586410-08-4 ≥98% ✓ 2009-12-01 20.623049723757 cay10616 resveratrols apoptosis cancers leukemia HL-60 cells HL60 HL 60 multidrug-resistance multidrug resistance multi-drug multi-drug-resistant daunorubicin etoposides citarabines phenols cytarabines HL60R 20.623049723757
13670 CAY10618 Exclusive 1202580-59-3 ≥95% ✓ 2011-03-18 15.319834254143 cay10618 NMPRTase Inhibitor nicotinamides phosphoribosyltransferases NAMPTs NAD+ cancers inhibitors autophagy inhibited inhibition inhibits 15.319834254143
13371 CAY10621 120005-55-2 ≥98% 2010-02-16 16.183024861878 cay10621 SKI 5C; SPHK 1 Inhibitor 5C sphingosines kinases Sphk sphingosine-1-phosphates S1P SphK1 SphK2 cancers inhibitors inhibits U937 cells proteins kinase C PKC SKI5C SKI-5C 16.183024861878
13687 CAY10622 Exclusive 1038549-25-5 ≥98% ✓ 2010-10-18 6.033314917127 cay10622 Rho kinases ROCK-I ROCK-II inhibitors inhibits inhibition 6.033314917127
13836 CAY10625 137346-42-0 ≥95% 2010-06-23 1.388011049723 cay10625 apoptosis Smac Diablo Survivin cancers antagonists INCENP doxorubicin caspase-3 caspase-7 Aurora B kinases Borealin caspases cell-permeable antagonists smac/diable smac-diablo 1.388011049723
13838 CAY10626 Exclusive 1202884-94-3 ≥98% ✓ 2010-08-23 19.375744492190 cay10626 PI3Kα mTOR cancers signal transduction inhibitors inhibits inhibition phosphatidylinositol 3-kinase PtdIns PIs 19.375744492190
13695 CAY10638 Exclusive - ≥98% ✓ 2010-10-01 27.760269337016 cay10638 Thiazolidinedione derivative prostaglandins 15-PGDHs thiazolidinediones inhibitors inhibits inhibition TZDs derivatives PGDHs dehydrogenases 27.760269337016
10804 CAY10649 Exclusive - ≥98% ✓ 2011-04-04 18.383052005167 cay10649 5-LO leukotrienes 5-lipoxygenases inhibitors inflammation smooth muscle contraction inhibition inhibited PMNL inflammatory 18.383052005167
10743 CAY10650 Exclusive 1233706-88-1 ≥98% ✓ 2011-06-14 23.657458563536 cay10650 cPLA2α cPLA2 inhibitors inflammation anti-inflammatory dermatitis metabolite phospholipase cytosolic prostaglandins PGs leukotrienes synthesis 10662 CAY-10650 CAY10641 CAY-10641 23.657458563536
10857 CAY10654 Exclusive 1298023-69-4 ≥98% ✓ 2011-06-21 8.237292817679 cay10654 CAY-10654 CAY 10654 quorum sense sensing signal signaling genes regulations infectious diseases lipids bacteria pseudomonas aeruginosa AHLs p. N-acylated-L-Homoserine lactones transcriptional activators LasR virulence factors immunosuppression leukocytes lymphocytes concanavalin A cytotoxicity 8.237292817679
13172 CBHA 174664-65-4 ≥98% 2009-06-24 33.912871516690 cbha Histone Deacetylase Inhibitor II; m-Carboxycinnamic Acid bis-Hydroxamide histones deacetylase HDACs HDAC1 HDAC3 apoptosis cancers neuroblastoma tumors retinoic acids inhibitors inhibits inhibition 33.912871516690
10787 CCG-100602 New 1207113-88-9 ≥98% 2011-11-22 14.999462860650 ccg-100602 Rho signaling signal transduction cancers inhibitors SRF serum response factors transcription CCG-1423 megakaryoblastic leukemia 1 MKL1 prostate analogs PC-3 CCG100602 CCG 100602 CCG1423 CCG 1423 cells DNA binding RHOA/C-mediated MKL-1 14.999462860650
10010350 CCG-1423 285986-88-1 >98% 2007-09-20 12.086362360782 ccg-1423 Rho signaling transduction cancers proliferations anti-proliferation anti-tumor serum response factor GTPase inhibits inhibitors inhibition signalling 12.086362360782
10012591 CCT018159 171009-07-7 ≥98% 2008-12-09 0.626408839779 cct018159 inhibitors inhibits inhibition cancers Hsp90s Hsp72 kinases tumor cells 17-AAG 17AAG CCT 018159 CCT-018159 0.626408839779
13519 Celastramycin A Exclusive 491600-94-3 ≥97% ✓ 2010-01-25 2.254419889502 celastramycin-a inhibits inhibitors bacterias mycobacterias inflammation IL-8 IL 8 IL8 HUVECs endothelial cells TNF-α TNFα TNF α inhibition interleukins tumors necrosis factors TNF alpha TNF.alpha. inflammatory bioactive endophytic celastraceae pyrroles 2.254419889502
11092 Ceranib-2 New - ≥98% 2011-12-19 45.494857785963 ceranib-2 ceramides ceramidase sphingosines sphingosine-1-phosphate S1P cells proliferation cancers paclitaxel tumors inhibitors lipids inhibits inhibition endogenous ovarian SKOV3 growth toxicity fatty acids N-acyl malignant apoptosis S1P non-lipid increases increased 45.494857785963
13322 CGP 57380 522629-08-9 ≥95% 2009-08-28 33.420939226519 cgp-57380 MNK1 Inhibitor inhibitors inhibits inhibitions MAPKs MAP kinases interacting interacting-kinase 1 MNK1 p38 JNK1 ERK1/2 PKC Src-like phosphorylation elF4E TNF-a TNF-α TNFα TNFa arsenite anisomycin PMA fetal calf serum 293 cells RAW264.7 toll-like receptors TLR2 HKLM TLR4 LPS TLR6/2 FSL TLR7 imiquimod TLR9 CpG DNA CGP57380 CGP-57380 33.420939226519
13156 Chaetocin 28097-03-2 ≥95% 2010-10-18 13.291246044912 chaetocin histones methyltransferases HMTs genes expressions epigenetics inhibitors oxidative stress cancers theoredoxin reductase-1 TrxR1 inhibits inhibition chetocin chaetocin A (+)-chaetocin piperazines 13.291246044912
11314 Chelerythrine chloride New 3895-92-9 ≥98% 2012-01-31 97.275187231430 chelerythrine-chloride NSC 646662; Broussonpapyrine chloride 6004-02-0 84282-43-9 chelerythrinium inhibitors inhibits inhibition PKC apoptosis cells signaling BclXL Bcl-2 cancers tumors p38 MAP kinases proteins JUNK benzophenanthridine alkaloids AC328200010 hydrochloride chlorid EINECS 223-444-9 2234449 3895-92-9 NSC 36405 NSC-36405 NSC36405 97.275187231430
13686 Chidamide 743420-02-2 ≥98% 2010-08-10 75.017168815223 chidamide HDACs histones deacetylase H3 acetylation colons cancers cells inhibitors inhibits inhibiton LoVo HT-29 HT29 HT 29 cycle arrest chidamides oncogenic signalling signaling kinases Benzamides 75.017168815223
13122 CHIR99021 252917-06-9 ≥98% 2011-02-18 77.993741120757 chir99021 CT 99021 GSK-3α GSK-3β inhibitors glucose metabolism insulin diabetes Wnt stem cells mice mouse CHIR-99021 CT-99021 CHIR 99021 CT99021 pyridines glucogen synthesis CHO-IR self-renewal 77.993741120757
10858 Cinnamyl-3,4-dihydroxy-α-Cyanocinnamate 132465-11-3 ≥97% 2011-06-28 19.880372928176 cinnamyl-3-4-dihydroxy-cyanocinnamate CDC inhibitors 5-LO 5LO 12LO 15LO 5 LO 12 LO 15 LO 12-LO 15-LO LTB4 lipoxygenases immune responses inflammation inhibits inhibition A23187 platelets shock assays 19.880372928176
10012583 cis-ACCP 777075-44-2 ≥95% 2009-02-10 0E-12 cis-accp MMP2 MMPs MMP 2 MMP9 MMP-9 9 tumors cancers extracellular matrix type IV collagen cell migration artritis osteoprosis 0E-12
10004235 cis-Resveratrol 61434-67-1 >98% (may contain 1-5% trans) 2008-02-05 27.162389502762 cis-resveratrol (Z)-Resveratrol antioxidant oxidative stress reactive oxygen species reactive nitrogen species ROS RNS NF-kb inflammations monoamine oxidase noradrenaline inhibits inhibitor inhibitions NF.kappa. atherosclerosis sirtuins AHR antagonists aryl hydrocarbon receptors 27.162389502762
10599 Cl-Amidine Exclusive New 913723-61-2 ≥95% ✓ 2011-08-29 30.807158042066 cl-amidine inhibitors PAD4 PAD-4 cancers epigenetics amidines proteins arginine deiminase 4 arthritis PADs cytotoxic HL-60 HL60 HT-29 mice joints auto antibodies HL 60 MCF7 MCF-7 MCF 7 HT29 citrulline IgG HT 29 cells lines ClA mouse serum autoantibodies auto-antibodies PAD3 PAD-3 3 PAD1 PAD-1 1 30.807158042066
70988 Clasto-Lactacystin β-lactone 154226-60-5 ≥98% 57.173314917127 clasto-lactacystin-lactone Omuralide; β-Clastolactacystin selective inhibitors neuroblastoma pleiotropic neurites 20S proteasomes inhibits streptomces cells Neuro2A apoptosis inhibition death 57.173314917127
9000760 Colchicine 64-86-8 ≥98% 2011-05-25 1.970441988950 colchicine microtubules polymerization mitosis anti-proliferation anti-inflammatory gout uric acids antiinflammatory antiproliferation 1.970441988950
10007412 Combrestatin A4 117048-59-6 ≥98% 2007-07-26 22.155548189072 combrestatin-a4 CRC 87-09; Combretastatin A4; CA4 inhibitors inhibition inhibits tubulin polymerization tumors CSA4 CSA-4 IMR32 neuroblastomas Hs746T carcinomas CFPAC-1 CFPAC1 MCF-7 MCF7 cancers inhibitory CA4 cells growth pancreatic breast gastric CA-4 combretastin 22.155548189072
10186 COX Inhibitor Pack - ≥98% 31.989613259668 cox-inhibitor-pack Cyclooxygenase-PAK cyclooxygenases PGHS-2 inducible synthases prostaglandins CAY10404 SC-560 SC-58125 valeroyl saliylate NS-398 aspirin resveratrol APHS inhibitors inhibits inhibition SC560 SC58125 NS 398 COX-2 COX2 COX-1 COX1 PGHS2 PGHS-1 PGHS1 10186 70330 70655 10006120 10007692 valdecoxib licofelone packs 31.989613259668
13183 CP 80633 135637-46-6 ≥98% 2010-05-20 11.495745856353 cp-80633 phosphodiesterases PDE cAMP cGMP asthma neurological diseases inhibitors inhibits inhibition PDE4 PDE1 PDE2 PDE3 PDE5 inflammation CP-80,633 CP-806333 CP80633 Pyrimidinones Pyrimidones 11.495745856353
13305 D 4476 301836-43-1 ≥98% 2009-07-29 37.654309392265 d-4476 Casein Kinase I Inhibitor inhibitors inhibits inhibition casein kinases 1 CK1 Ck1δ TGF-β TGFβ type-1 receptors ALK5 PKD1 p38α MAPK kinases phosphorylation FOXO1a RhoB p53 Smad3 D4476 37.654309392265
13197 DAPT 208255-80-5 ≥95% 2010-09-16 16.385745856353 dapt GSI-IX amyloids precursors proteins APP Notch beta amyloid Aβ Alzheimer’s disease inhibitors inhibits inhibition γ-secretase Aβ42 cells signaling signals differentiation GSIIX GSI IX Dipeptides 16.385745856353
10961 Demethoxycurcumin New 22608-11-3 ≥98% 2011-09-23 5.123579797029 demethoxycurcumin DMC curcumin cancers transcription genes expressions p300 Wnt/β-catenin iNOS inflammation proliferation cells p300 coactivator inhibits lipopolysaccharides inhibitor inhibition 5.123579797029
70680 Diclofenac (sodium salt) 15307-79-6 ≥99% 33.720924902803 diclofenac-sodium-salt Voltaren; Ecofenac; Benfofen cyclooxygenases inhibitors NSAIDs COX-1 COX-2 nonsteroidal anti-inflammatory drugs cox1 cox2 pghs1 pghs2 pghs-1 pghs-2 prostaglandin H synthases synthase-1 synthase-2 inhibits 33.720924902803
9000556 Dimebolin Exclusive 3613-73-8 ≥98% ✓ 2010-01-12 12.592592592592 dimebolin Dimebon™ neurodegeneration Alzheimer's diseases Huntington's neuroprotection cognition inhibitors inhibition β-amyloid calcium channels NMDA glutamate receptors mitochondria dimebone dimeboline preparation 84 Dimebolin 12687-54-6 20684-30-4 inhibited Indoles 12.592592592592
10011349 Dimebolin (hydrochloride) 97657-92-6 ≥98% 2010-02-19 10.793650793650 dimebolin-hydrochloride neurodegeneration Alzheimer's diseases Huntington's neuroprotection cognition inhibitors inhibits inhibition calcium channles β-amyloid β amyloid NMDA glutamate receptors mitochondria dimeboline dimebon neurochemistry neuroscience Indoles 10.793650793650
81050 Diphenyleneiodonium Chloride 4673-26-1 ≥99% 12.195676795580 diphenyleneiodonium-chloride DPI Chloride nitric oxide synthases inhibitors iNOS eNOS dibenziodolium 12.195676795580
10010948 DL-Propargyl Glycine (hydrochloride) - ≥98% 2008-08-19 43.013158379374 dl-propargyl-glycine-hydrochloride PAG (hydrochloride) H2S gasotransmitter inhibitor inhibits inhibition CSE vasodilation inflammation propargylglycine 43.013158379374
9000639 Docosahexaenoyl Serotonin Exclusive 283601-58-1 ≥98% ✓ 2010-05-18 5.120520915548 docosahexaenoyl-serotonin N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA L-alpha-Glycerylphosphorylcholine L alpha Glycerylphosphorylcholine Glycerophospholipids Choline Choline Glycerophospholipids Phosphoglycerides Choline 3-Phosphocholine Glycerol Glycerylphosphorylcholine Glycerophosphate Choline Glycerol 3-Phosphocholine Glycerol 3 Phosphocholine Choline Phosphoglycerides Glycerophosphorylcholine Choline Glycerophosphate Alphoscerate Choline Phosphatidylcholines Choline Alphoscerate Alfoscerate Choline Phosphatidylcholine Choline Alfoscerate 5.120520915548
13245 Donepezil 120014-06-4 ≥95% 2010-03-08 3.829033149171 donepezil Aricept® acetylcholine neurotransmitters acetylcholinesterase inhibitors inhibits inhibition central nervous system Alzheimer's diseases cognition memory dementia Donezepil signaling signalling AchE CNS behavior (±)-E 2020 (+/-)-E 2020 E2020 3.829033149171
10460 Doramapimod 285983-48-4 ≥98% 2011-06-02 18.385745856353 doramapimod BIRB-796 p38 MAPKs inflammation TNFα TNF-α TNF α TNFalpha TNF-alpha TNF alpha JNKs inhibitors proteins kinases tumors necrosis factors LPS THP.1 cells THP1 BIRB796 BIRB 796 mitogen activated mitogen-activated proinflammatory cytokins interleukin-1 IL IL-1 interleukin 1 18.385745856353
10010302 DRB 53-85-0 ≥98% 2008-01-21 2.614201688497 drb Benzimidazole; NSC 401575 cancers HIV P53 apoptosis CDK7 CDK9 CTD CKI CKII adenosine inhibitors inhibits inhibition transcription RNA polymerase cell cycles adenocarcinoma transactivator tat 2.614201688497
70645 DuP-697 88149-94-4 ≥96% 14.240696132596 dup-697 COX-2 COX2 PGHS2 prostaglandins H synthases inhibitors inhibits selective time-dependent cyclooxygenase DuP697 DuP 697 14.240696132596
10007963 E-64 66701-25-5 ≥98% 2009-11-12 54.998232044198 e-64 inhibitors cysteine proteases cathepsins papain calpain irreversible inhibition inhibited E64 E 64 54.998232044198
10007964 E-64c 76684-89-4 ≥98% 2006-08-02 52.925580110497 e-64c EP 475; Loxistatin Acid; NSC 694279 E-64 cysteine protease cell cycle inhibitor E-64d 52.925580110497
13533 E-64d 88321-09-9 ≥98% 2010-08-16 15.763895027624 e-64d EP 453; EST; NSC 694281; Loxistatin; E-64c ethyl ester; Aloxistatin cysteine protease proteins degradation lysosome inhibitors inhibits inhibition calpain cathepsin E64d E 64d 64 207396-71-2 cells cancers carcinomas A431 E-64d Morphinans 15.763895027624
70530 Ebselen 60940-34-3 ≥99% 221.665497237568 ebselen glutathione peroxidase peroxynitrite oxidative injury stress cyclooxygenases lipoxygenases LOX 5-LO 12-LO 15-LO cyclooxygenases inhibitors COX-1 COX-2 cox1 cox2 pghs1 pghs2 pghs-1 pghs-2 prostaglandin H synthases synthase-1 synthase-2 inhibits mimics scavengers 221.665497237568
13352 EHNA (hydrochloride) New - ≥98% 2011-10-07 672.662897072258 ehna-hydrochloride 51350-19-7 79763-32-9 59262-86-1 ADA reversible adenosine deaminase inhibitors inhibits inhibition cGMP PDE2 potent PDE1 PDE3 PDE4 phosphodiesterase ardioprotective ischemia stem cells 672.662897072258
9000640 Eicosapentaenoyl Serotonin Exclusive 199875-71-3 ≥98% ✓ 2010-09-10 1.131144435675 eicosapentaenoyl-serotonin N-arachidonoyl serotonins AA-5-HT AA5HT AA 5 HT AA-5HT AA5HT antagonists fatty acids Amide hydrolase FAAH transient receptors potential vanilloid type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA Triacylglycerols Triacylglycerol Triglycerides 1.131144435675
90120 Eicosatetraynoic Acid 1191-85-1 >98% 5.221602209945 eicosatetraynoic-acid ETYA inhibitors inhibits lipoxygenases cyclooxygenases prostaglandin h synthases cox lo acetylene PPAR ligands peroxisome proliferator-activated receptors fatty acids 5.221602209945
10569 Ellagic Acid 476-66-4 ≥95% 2010-10-13 6.173474524248 ellagic-acid Lagistase; TBBD; Gallogen polyphenols, antioxidants, cancers inflammation cytochrome P450s CYP450 epigenetics genes expression histones modifications alizarin yellow G 91006 elagostasine 77415-21-5 124590-32-5 PRMTs inflammatory anti-carcinogenic anti-mutagenic organ-preserving antimutagenic antiinflammatory Acid Benzoaric Benzoaric Acid Acid Ellagic Ellagic Acid 6.173474524248
10010571 Entacapone-d10 - ≥98% 2008-04-14 11.600773480663 entacapone-d10 Parkinsons dieseases inhibitors inhibits inhibition SPI nitrocatechols catechol-o-methyl blood-brain barrier neurochemistry 11.600773480663
10924 Epothilone B 152044-54-7 ≥95% 2011-07-27 17.617403314917 epothilone-b macrolides inhibitors inhibits inhibition tubulin microtubules polymerization cancers cells cycle mitotic arrest mitosis Hs578T HeLa KB3-1 KB31 KBV-1 KBV1 cytoskeletal 17.617403314917
10007806 Epoxomicin 134381-21-8 ≥98% 2008-12-09 46.601679558011 epoxomicin BU 4061T inhibitors inhibits inhibition proteins degradation 20S proteasomes antitumors bones formation Parkinsons diseases anti-tumors 46.601679558011
10010238 Erbstatin Analog 63177-57-1 ≥98% 2008-06-06 0.934806629835 erbstatin-analog Methyl 2,5-dihydoxycinnamate analogs EGF EGFR inhibitors inhibits inhibition tyrosine kinase DNA synthesis cell cycle proliferation cancers 0.934806629835
10483 Erlotinib 183321-74-6 ≥98% 2010-08-11 35.239654848584 erlotinib Tarceva™; CP 358,774; NSC 718781 tyrosine kinase inhibitor inhibits inhibiting epidermal growth factor receptors EGFR cancers tumor cyclin-dependent cyclin dependent kinase 2 CDK-2 CDK 2 CDK2 JAK-2 JAK2 JAK JAK2V617F CP-358,774 CP-358774 CP 358774 CP358774 CP358,774 NSC-718781 NSC718781 OSI-744 OSI744 R-1415 R1415 R 1415 OSI 744 Quinazolines 35.239654848584
10012088 Ethyl-L-NIO (hydrochloride) 150403-97-7 ≥95% 2008-08-14 6.846657458563 ethyl-l-nio-hydrochloride L-N5-(1-Iminobutyl)ornithine hydrochloride nitric oxide synthase NOS iNOs nNOS selective inhibitors inhibits inhibition 6.846657458563
10009798 EX-527 49843-98-3 ≥98% 2009-10-23 26.102891344382 ex-527 sirtuins SIRT1 histones deacetylase HDAC energy metabolism inflammation inhibitors p53 DNA damage 848193-68-0 848193-69-1 26.102891344382
10610 F-Amidine (trifluoroacetate salt) Exclusive New - ≥95% ✓ 2011-09-23 18.138630420943 f-amidine-trifluoroacetate-salt proteins arginine deiminase 4 PAD4 cancers arthritis inhibitors histones genes expression cysteine PAD1 PAD3 cytotoxic HL-60 MCF7 HT-29 877617-46-4 PADs PAD-1 PAD-3 PAD-4 peptidyl arginine 18.138630420943
10010501 Farnesyl Thiosalicylic Acid 162520-00-5 ≥96% 2008-06-02 21.011473296501 farnesyl-thiosalicylic-acid Salirasib; FTS ras inhibitors inhibition inhibits cancer anti-cancer anticancer prenylation farnesylation signal transduction oncogene atherosclerosis farnesylthiosalicylic acid 21.011473296501
13175 Farnesyl Thiosalicylic Acid Amide Exclusive 1092521-74-8 ≥96% ✓ 2009-02-26 9.088825966851 farnesyl-thiosalicylic-acid-amide Salirasib Amide; FTS Amide Ras degradation cells signaling signalling tumors glioblastoma cancers inhibitors inhibits inhibition 9.088825966851
13563 FIPI Exclusive 939055-18-2 ≥98% ✓ 2010-03-24 28.454795580110 fipi 5-Fluoro-2-Indolyl des-Chlorohalopemide Phospholipases D PLD phosphatidic acids PA Ras activation cells spreading stress fiber formation chemotaxis membrane vesicles trafficking halopemide inhibitors inhibits inhibition PLD1 PLD2 F-actin cytoskeletons inflammation arthritis Pharmascience Brand of Domperidone Maleate Stadapharm Brand of Domperidone Maleate Ratiopharm Brand of Domperidone Maleate Taxandria Brand of Domperidone Maleate Novopharm Brand of Domperidone Maleate Nu-Pharm Brand of Domperidone Maleate Nu Pharm Brand of Domperidone Maleate Apotex Brand of Domperidone Maleate Hexal Brand of Domperidone Maleate Aliud Brand of Domperidone Maleate Teva Brand of Domperidone Maleate Pierre Fabre Brand of Domperidone Gry Brand of Domperidone Maleate Rottapharm Brand of Domperidone Monohydrochloride, Domperidone Domperidone Monohydrochloride Janssen Brand of Domperidone Domperidone Maleate (1:1) Maleate, Domperidone Domperidone Maleate Gamir Domperidona Stada Domperidon ratio-Domperidone ratio Domperidone Hexal Domperidon Domperidona Gamir Novo-Domperidone Novo Domperidone Domperidon Stada Domperidon Hexal PMS-Domperidone PMS Domperidone Domperidon-TEVA Domperidon TEVA Apo-Domperidone Apo Domperidone Nu-Domperidone Nu Domperidone Domperidon AL Domperidone Gastrocure Domperidon R-33,812 Nauzelin Motilium R-33812 R33,812 Péridys Domidon R33812 28.454795580110
13287 FK-866 658084-64-1 ≥98% 2009-07-21 71.532939226519 fk-866 K 22.175 nicotinamides phosphoribosyltransferase NAMPT NamPRT PBEF visfatin mononucleotides adenine dinucleotide NAD+ inhibitors inhibitis inhibition cancers apoptosis SIRT1 autophagy FK866 FK 866 K22.175 K 22175 K22175 NamPRT PBEF visfatin carcinoma cells autophagy 71.532939226519
13179 FKGK 11 1071000-98-0 ≥98% 2009-06-30 12.592353591160 fkgk-11 Phospholipases A2 iPLA2 inhibitors signal transduction inhibition PLAs 12.592353591160
70250 (±)-Flurbiprofen 5104-49-4 ≥99% 83.073017188458 -flurbiprofen Ansaid cyclooxygenases inhibitors NSAIDs COX-1 COX-2 nonsteroidal anti-inflammatory drugs cox1 cox2 pghs1 pghs2 pghs-1 pghs-2 prostaglandin H synthases neurochemistry synthase-1 synthase-2 inhibits 51543-38-5 83.073017188458
10010337 Fluvastatin (sodium salt) 93957-55-2 ≥98% 2008-02-27 12.218204419889 fluvastatin-sodium-salt atherosclerosis HMG-CoA reductases LDL LDL-c HDL HDL-c statin cholesterol heart disease CVD inhibitors inhibits inhibition 12.218204419889
10039 FR122047 (hydrate) - ≥98% 9.722624309392 fr122047-hydrate 130717-51-0 FR-122047 cyclooxygenases COX-1 inhibitors hydrates hydrochlorides COX1 PGHS1 PGHS-1 prostaglandin synthases inhibition inhibits selective selectivity platelet aggregation antiinflammatory atherosclerosis 9.722624309392
13227 Fumonisin B2 116355-84-1 ≥98% 2009-11-11 63.157197326239 fumonisin-b2 mycotoxins fungus corn grains sphingosines inhibitors N-acyltransferase apoptosis sphingolipids hepatotoxicity nephrotoxicity fungi 63.157197326239
70540 Furegrelate (sodium salt) 85666-17-7 ≥99% 1.726537753222 furegrelate-sodium-salt U-63557A thromboxanes synthases inhibitors inhibits inhibition salts atherosclerosis 1.726537753222
13200 G-418 Sulfate 108321-42-2 ≥95% 2009-11-09 0.119889502762 g-418-sulfate Geneticin aminoglycoside antibiotic gentamicin transfection stable transfectants engineered 49863-47-0 7664-93-9 49662-05-7 0.119889502762
10008346 Gabapentin 60142-96-3 ≥98% 2006-04-20 25.639433701658 gabapentin Neurontin® antiepileptic drugs Gamma-aminobutyric acids GABA neurotransmitters receptors spinal cord analogs anticonvulsants analgeics neuropathics pain syndromes Complex Regional types CRPS1 multiple sclerosis dysesthesias cancers HIV infections CNS central nervous systems calcium channels .gamma.-aminobutyric g-aminobutyric neurochemistry 25.639433701658
10566 Garcinol New 78824-30-3 ≥95% 2011-10-25 11.209988941663 garcinol Camboginol inhibits inhibitors inhibition histones acetyltransferases HATs p300 PCAF GCN5 neurogenesis stem cells apoptosis cancers antiinflammatory anti-inflammatory inflammation neuroscience genes expressions regulations epigenetics 11.209988941663
13166 Gefitinib 184475-35-2 ≥98% 2010-02-11 29.522580740204 gefitinib Iressa™; ZD1839 EGFR-TK EGFRs TKs epidermal growth factors inhibitors cancers signal transduction tyrosine kinases inhibits inhibited NSCLC Quinazolinones 29.522580740204
13355 Geldanamycin 30562-34-6 ≥98% 2010-07-29 28.262476142641 geldanamycin NSC 122750 NSC 212518 antibiotics heat shock proteins 90 Hsp90 GRP94 gp96 genes expression cells proliferation apoptosis angiogenesis c-jun adenocarcinoma cancers AP-1 steroids receptors 2,5-Cyclohexadiene-1,4-Diones 1,4-Benzoquinones 1,2-Benzoquinones p-Benzoquinones-o-Benzoquinones Benzoquinones Benzodiones Quinones 28.262476142641
10010622 Genipin 6902-77-8 ≥98% 2008-05-09 99.322569060774 genipin (+)-Genipin obesity diabeties glucose insulin mitochondria UCP2 pancreatic .beta. cells anti-inflammatory antiinflammatory angiogenesis inhibitors inhibits inhibition uncoupling proteins 2 un-coupling angiogenesis apotosis diabetes inflammation metabolism obesity 99.322569060774
10948 GN25 New 1227401-27-5 ≥98% 2011-11-30 109.977679558011 gn25 tumors suppressors p53 cancers K-Ras Snail inhibitors mutations exocytosis cells proliferatiion analogs MKN-45 MKN45 MKN 45 A549 HCT116 GN-25 GN 25 genes humans 2-thio-dimethoxy naphthoquinone binding tumors 109.977679558011
13311 Gö 6983 133053-19-7 ≥98% 2009-10-07 38.994546756701 g-6983 proteins kinases C PKC α β γ δ ζ µ hearts cardioprotection ischemia reperfusion injuries contractile dyfunction alpha beta gamma delta zeta micro Goe Goe6983 Go-6983 Go 6983 38.994546756701
13009 GSK264220A 685506-42-7 ≥98% 2009-10-21 5.716298342542 gsk264220a inhibitors endothelial lipases high-density lipoproteins cholesterol HDL-C HDL cardiovascular diseases inhibition inhibited ET 5.716298342542
13127 GW 4869 6823-69-4 ≥90% 2009-06-10 48.048139963167 gw-4869 inhibitors sphingomyelin sphingomyelinase neutral acidic TNF-α ceramides cells death GW4869 gw-4869 48.048139963167
10010556 H-89 127243-85-0 ≥98% 2008-07-08 23.672541436465 h-89 5-Isoquinolinesulfonamide; Protein Kinase Inhibitor H-89 inhibitors inhibits inhibition PKA cAMP cell signaling protein kinase S6K1 MSK1 ROCK-II ROCKII PKB.alpha. PKBalpha PKBa MAPKAP-K1b MAPKAPK1b H89 H 89 23.672541436465
10010249 H-8 (hydrochloride) 113276-94-1 ≥98% 2008-07-17 12.649364640884 h-8-hydrochloride Protein Kinase Inhibitor H-8 PKA PKG PKC MLCK cyclin C CDK8 cyclin H CDK7 p36 signal transduction inhibitor inhibits inhibition transcription 84478-11-5 12.649364640884
13312 H-9 (hydrochloride) - ≥98% 2009-07-14 12.235939226519 h-9-hydrochloride Protein Kinase Inhibitor H-9 proteins kinases inhibitors inhibits inhibitions PKCs PKAs PKGs cGMPs cAMPs signal transductions competitive potent PKA-mediated mediated phosphorylation 84468-17-7 12.235939226519
10010559 HA-1077 (hydrochloride) 203911-27-7 ≥98% 2008-09-03 68.667826887661 ha-1077-hydrochloride Eril; Fasudil; AT-877 protein kinase inhibitors inhibits inhibition ROCK-II ROCKII PRK2 MSK1 MAPKAP-K1b vasodilation hypertension diabetes renal nephropathy cancers 105628-07-7 AT877 AT 877 hydrochloride dihydrochloride monohydrochloride HCl HA1077 HA 1077 68.667826887661
13205 Halopemide Exclusive 59831-65-1 ≥98% ✓ 2009-04-21 16.019558011050 halopemide R34301; NSC 354856 inhibitors phospholipases D PLD PLD1 PLD2 dopamine receptors inhibits inhibition potent cells DP nueraleptic 16.019558011050
10995 Harmaline New 304-21-2 ≥98% 2011-10-11 1.790779319947 harmaline inhibitors monoamine oxidases MAOI receptor agonists inverse agonists NMDA herbal mixtures forensics bath salts spices plants N-methyl-D-aspartate inhibits inhibition adulterant CBs cannabinoids hallucinogenic tryptamines 1.790779319947
10576 HC Toxin 83209-65-8 ≥95% 2010-11-10 39.746995856353 hc-toxin Toxin I (Helminthosporium carbonum) inhibitors histones deacetylases HDACs cancers genes regulation regulates regulators epigenetics HC-toxins cell-permable cells permable 15-lipoxygenase-1 15-LO-1 LOs lipoxygenase 15 1 tetrapeptides peptides helminthosporium carbonums cochliobolus maize pathogens Isomerases Amino Acid Acid Isomerases Amino Racemases Amino Acid Amino Acid Isomerases Acid Racemases Amino Amino Acid Racemases 39.746995856353
10011038 Hemopressin - 2009-08-13 32.880710339384 hemopressin peptides antagonist inhibitors inhibits inhibition hypertension binding asoactive vasoactive cannabinoids cbs synthetic 32.880710339384
13295 HNHA 926908-04-5 ≥98% 2009-09-03 41.124732088047 hnha Histone Deacetylase Inhibitor VI inhibitors inhibits inhibition histones deacetylase HDACs cancers fibrosarcoma HT1080 cells hyperacetylation p21 genes expressions transcription cycles arrest tumor growth murine xenograph human umbilical vein endothelial HUVECs tubes formation migration vascular endothelial factors VEGF retinal neovascularization angiogenesis 41.124732088047
10134 HQL-79 162641-16-9 ≥98% 152.411151012891 hql-79 inhibitors prostaglandins synthases PGD2 L-PGDS tetrazoles HQL79 inhibits lipocalin-type 152.411151012891
10699 HTS 01037 682741-29-3 ≥98% 2011-03-14 15.947182320442 hts-01037 adipocytes fatty acids binding proteins FABP4 AFABP A-FABP aP2 macrophages lipocytes diabetes atherosclerosis HTS-01037 HTS01037 Isomerases Amino Acid Acid Isomerases Amino Racemases Amino Acid Amino Acid Isomerases Acid Racemases Amino Amino Acid Racemases 15.947182320442
10888 HZ52 New 1077626-51-7 2011-09-30 19.619849784228 hz52 inhibitors inhibits inhibition 5-LO 5 LO 5LO leukotrienes LTBs LTB4 LTs leukocytes neutrophils inflammation shock HZ-52 HZ 52 19.619849784228
13347 IBMX 28822-58-4 ≥98% 2009-10-27 457.229152854512 ibmx NSC 165960; 1-Methyl-3-Isobutylxanthine; Isobutylmethylxanthine inhibitor cAMP cGMP phophodiesterases PDE1 PDE2 PDE3 PDE4 PDE5 PDE7 PDE11 PDE8A PDE8B PDE9 cyclic-nucleotides methylxanthines caffeine theophylline adenosine receptors antagonist SC 2964 SC-2964 SC2964 IMX NSC165960 NSC-165960 xanthine 457.229152854512
70280 (±)-Ibuprofen 15687-27-1 ≥99% 26.545411574306 -ibuprofen Motrin PPAR cyclooxygenases inhibitors NSAIDs COX-1 COX-2 nonsteroidal anti-inflammatory drugs cox1 cox2 pghs1 pghs2 pghs-1 pghs-2 prostaglandin H synthases synthase-1 synthase-2 inhibits peroxisome proliferator-activated receptors neurochemistry 26.545411574306
13624 Icariin 489-32-7 ≥97% 2010-02-11 1.738950276242 icariin PDE5 inhibitors flavonoids differentiation cancers proliferation flavonols E brevicornum horny goat weed BMP2 ED erectile dysfunction 2-Phenyl-Benzopyrans 2 Phenyl Benzopyrans 2-Phenyl-Chromenes 2 Phenyl Chromenes Bioflavonoids Flavonoids 1.738950276242
10215 IDFP 615250-02-7 ≥98% 2009-03-09 15.622209944751 idfp Isopropyl Dodecylfluorophosphonate CB1 agonist nerve agent serins organophophorus MAGL inhibitors inhibits inhibition FAAH 2-AG 2AG AEA arachidonic acids MGL inhibitors cannabinoids 15.622209944751
13323 IM-54 861891-50-1 ≥95% 2009-10-14 2.769281767956 im-54 inhibitors necrosis necrotic cells death peroxide HL-60 leukemia apoptosis PKC S6K1 protein kinases C S6 1 indolymaleimide 2.769281767956
13139 Imatinib (mesylate) 220127-57-1 ≥98% 2009-04-21 48.968448587074 imatinib-mesylate CGP57148B; Glivec; Gleevec; STI-571 inhibitors tyrosine kinase cancer chronic myelogenous leukemia CML c-ABL kits c-kit platelet-derived growth factor receptors imatinib mesilate 152459-95-5 75-75-2 gleevec 48.968448587074
13314 Indirubin-3'-monoxime 160807-49-8 ≥98% 2009-07-15 12.044033149171 indirubin-3-monoxime glycogen synthase kinase-3β GSK-3β tau proteins Alzheimer's diseases cyclin-dependent kinases CDK CDK1 cyclin A B E D1 CDK4 CDK2 CDK5 p35 growth proliferation synchronization cells arrest G2/M phases phosphorylation inhibits inhibition inhibitors 12.044033149171
70270 Indomethacin 53-86-1 ≥99% 30.082153361624 indomethacin Indocin cyclooxygenases inhibitors NSAIDs COX-1 COX-2 nonsteroidal anti-inflammatory drugs cox1 cox2 pghs1 pghs2 pghs-1 pghs-2 prostaglandin synthases synthase-1 synthase-2 PPARs peroxisome proliferator-activated receptors inhibits neurochemistry 30.082153361624
70271 Indomethacin heptyl ester - ≥98% 3.228397790055 indomethacin-heptyl-ester esters derivatives COX-2 cox2 pghs2 pghs-2 prostaglandin synthases synthase-2 inhibitors inhibits selective selectivity cyclooxygenase 3.228397790055
70273 Indomethacin N-octyl amide - ≥98% 21.691063535911 indomethacin-n-octyl-amide aromatic amides inhibitors inhibits COX-2 COX2 PGHS2 PGHS-2 prostaglandin synthases cyclooxygenases selective selectivity 21.691063535911
10617 IU1 314245-33-5 ≥98% 2011-01-31 37.766975138121 iu1 inhibitors ubiquitin proteasomes proteins degradation oxidative injury inhibited inhibition 37.766975138121
13659 IWR-1-endo 1127442-82-3 ≥98% 2010-03-23 11.352596685083 iwr-1-endo Wnt cancers embryonic developments tissues homeostasis embryogenesis tumorigenesis stem cells β-catenin genes expression transcription inhibitors inhibits inhibition proteasomes Apc Axin2 Ck1 Gsk3β IWR-1-exoendo-1,3(4)-beta-D-glucanase Endo-1,3(4)-beta-Glucanase Endo-1,3(4)-B-Glucanase beta-(1-3,1-4)glucanase 11.352596685083
13598 IWR-1-exo 1127442-87-8 ≥98% 2010-03-23 9.123314917128 iwr-1-exo Wnt cancers embryonic developments tissues homeostasis embryogenesis tumorigenesis stem cells β-catenin genes expressio Cellobiohydrolase, 1,4-beta-D-Glucan 1,4-beta-D-Glucan Cellobiohydrolase 1,4 beta D Glucan Cellobiohydrolase 1,4-beta-Cellobiosidase, Cellulose Cellulose 1,4-beta-Cellobiosidase Cellulose 1,4 beta Cellobiosidase Beta-Glucancellobiohydrolase Beta Glucancellobiohydrolase Exo-Cellobiohydrolase Exo Cellobiohydrolase Cellobiohydrolase II Cellobiohydrolase I Cellobiohydrolase A Cellobiohydrolase Exoglucanase II CEL1 Protein CbhI Proteinn transcription inhibitors inhibits inhibition controls 9.123314917128
10011246 Janex 1 202475-60-3 ≥98% 2008-12-17 2.433149171271 janex-1 WHI-P131 inhibitors inhibits inhibition JAK3 apoptosis leukemias anti-inflammatory antiinflammatory lymphocytes WHIP131 Janex 1 2.433149171271
10641 JGB1741 Exclusive 1256375-38-8 ≥98% ✓ 2011-06-20 17.711065509076 jgb1741 ILS-JGB-1741 inhibitors SIRT1 breasts cancers cells proliferation apoptosis p53 histones acetylation genes energy homeostasis regulation deacetylases sirtuins NAD+ inhibits inhibition SIRT2 SIRT3 ILS JGB 1,741 1741 SIRTs JGB-1741 JGB-1,741 17.711065509076
10741 (±)-JQ1 Exclusive New 1268524-69-1 ≥98% ✓ 2011-12-08 102.817204168322 -jq1 BET bromodomain inhibitors BRD4 BRD2 transcriptions cancers BRD-4 BRD-2 BRDs extra terminal domains proteins BRD4 BRD2 BRD3 BRD-3 inflammatory genes viral hosts expressions mitosis 102.817204168322
13158 JZL 184 1101854-58-3 ≥97% 2009-01-26 160.348107734806 jzl-184 2-AG 2AG MAGL inhibitors inhibits inhibition endocannabinoids pains analgesia MGL inhibitor JZL184 JZL-184 cannabinoids 160.348107734806
13668 JZL 195 - ≥98% 2010-02-10 120.234751381215 jzl-195 fatty acid amide hydrolase FAAH monoacylglycerol lipase MAGL endocannabinoids arachidonoyl ethanolamide AEA 2-arachidonoylglycerol 2-AG inibitors inhibition inhibits PF-3845 PF 3845 PF3845 JZL195 JZL-195 JZL184 antinociception pain catalepsy hypomotility CB1 2AG cannabinoids inhibitors cbs sythetic Methylenedioxybenzenes 1,3-Dioxaindans 1,3 Dioxaindans 1,3-Dioxindans 1,3 Dioxindans Benzodioxoles 120.234751381215
10010239 Kenpaullone 142273-20-9 >98% 2007-09-04 12.153692449355 kenpaullone NSC 664704; 9-Bromopaullone GSK-3.beta. cyclin-dependent kinase cyclin CDK inhibitors inhibits inhibition proliferations cell cycle cancers 12.153692449355
10006661 Ketoprofen 22071-15-4 ≥98% 2005-05-18 14.209844826410 ketoprofen 2-(3-benzoylphenyl)propionic Acid; Oruvail; Orudis COX cyclooxygenases NSAIDS nonsteroidal non-steroidal anti-inflammatory drugs prostaglandins PGs inflammations pain racemates racemic R-enantiomers cytokines non-selective inhibits inhibitor inhibition 14.209844826410
9001148 Ketorolac New 74103-06-3 ≥98% 2012-01-12 102.551822259998 ketorolac Sprix®; Acular PF®; RS 37619; Acular LS® analgesic NSAIDs COX inhibition inhibits inhibitors ocular pain inflammation PGE2 non steroidal anti-inflammatory antiinflammatory drugs heteroaryl acetic acids derivatives cyclooxygenase opthalmalic solutions ocular COX-1 COX-2 COX1 COX2 racemic 66635-83-4 102.551822259998
70690 Ketorolac (tromethamine salt) 74103-07-4 >99% 18.743208512379 ketorolac-tromethamine-salt Toradol cyclooxygenases inhibitors NSAIDs COX-1 COX-2 nonsteroidal anti-inflammatory drugs cox1 cox2 pghs1 pghs2 pghs-1 pghs-2 prostaglandin H synthases synthase-1 synthase-2 inhibits 18.743208512379
13243 KH7 330676-02-3 ≥98% 2009-09-18 121.275626151013 kh7 sAC soluble adenylyl cyclase cAMP inhibitors inhibits inhibition cells signaling signal transduction second messenger KH 7 KH-7 signalling cyclic AMP 121.275626151013
10009437 Kifunensine 109944-15-2 >98% 2007-04-30 391.374613259668 kifunensine FR 900494 glycoproteins glycosidases mannosidases inhibitors kitasatosporia kifunense inhibition inhibited 391.374613259668
13318 KN-62 127191-97-3 ≥98% 2009-07-16 23.655093922651 kn-62 inhibitors calcium calmodulin-dependent kinase II CaM kinase II purinergic receptors P2RX7 P2X7 inhibition inhibited selective permeableCaMKII calcium ca modulation CaMK11CaMK2 23.655093922651
13319 KN-93 139298-40-1 ≥98% 2009-08-05 36.235230202577 kn-93 inhibitors inhibits inhibition Ca2+ calmodulin dependent Ca2+/calmodulin-dependent kinase II CaMKII histamine parietal cells cardiac myocytes 5-LO 5-lipoxygenase HIF-1a HIF-1α HIF1α colon cancers phosphorylation CAM 36.235230202577
10011011 KT 5720 108068-98-0 ≥98% 2009-01-20 124.005146014206 kt-5720 PKAs cAMPs signaling proteins kinase inhibitors inhibits inhibition phosphorylase kinase PDK1 MEK MSK1 PKα GSK3β KT5720 KT-5720 124.005146014206
10010965 KT 5823 126643-37-6 ≥95% 2009-01-15 137.926464088397 kt-5823 cGMP PKGs proteins kinases G inhibitors inhibits inhibition nitric oxides NO antibiotic KT5823 KT-5823 indolocarbazoles alkaloid PKG 137.926464088397
13627 Lansoprazole 103577-45-3 ≥98% 2010-07-19 1.615027624309 lansoprazole Prevacid; AG-1749 proton pumps inhibitors inhibits inhibition ATPases gastric acids ulcers cytochromes P450 CYP2C19 CYP3A4 Agopton Alter Cinfa Davur Lancid Lanpro Ogastro PP/K-10 154727-72-7 909251-59-8 secretion intra gastric pH increasing Sulfoxides, 2-Methylpyridine 2-Benzimidazole 2-Benzimidazole Sulfoxides, 2-Methylpyridine 2-Methylpyridine 2-Benzimidazole Sulfoxides 2 Methylpyridine 2 Benzimidazole Sulfoxides 2-Pyridinylmethylsulfinyl-2-Benzimidazoles 2 Pyridinylmethylsulfinyl 2 Benzimidazoles Sulfoxides, Benzimidazole Methylpyridine Methylpyridine Sulfoxides, Benzimidazole Benzimidazole Methylpyridine Sulfoxides 2-Pyridinylmethylsulfinylbenzimidazoles 2 Pyridinylmethylsulfinylbenzimidazoles 1.615027624309
10010631 Latrunculin B 76343-94-7 ≥97% 2009-02-20 67.237513812154 latrunculin-b monomeric actins G-actin G actins F-actin F inhibitors inhibits inhibition cytoskeleton 67.237513812154
10010329 Lavendustin C 125697-93-0 ≥98% 2008-07-08 13.559254143646 lavendustin-c HDBA; NSC 666251 EGFR kinases tyrosine pp60c-src pp60csrc CamKII SOD neutrophil activation erbstatin inhibitor inhibits inhibition Lavendustin-C 13.559254143646
16844 LED209 245342-14-7 ≥98% 2009-03-09 0.880386740331 led209 QseC virulence factors norepinephrine epinephrine pathogen AI-3 AI3 bacteria genes expression 0.880386740331
10004976 Leptomycin B 87081-35-4 >98% 2008-03-19 4.016298342541 leptomycin-b NSC 364372; Mantuamycin; LMB; Elactocin antibiotics cell cycles p53 antifungals proliferation nuclear transport inhibits inhibitors inhibition inhibiting export signals receptors NES RNA REV-response elements HIV-1 4D 3E3 4.016298342541
13810 Limaprost 74397-12-9 >98% 43.118038674033 limaprost 17α,20-dimethyl-Δ2-Prostaglandin E1; 17α,20-dimethyl-Δ2-PGE1 PGE1 analogs inhibitors platelets aggregation prostaglandins 43.118038674033
16833 Lisinopril 76547-98-3 ≥98% 2009-03-09 2.545248618785 lisinopril MK 522; MK 521 inhibitors inhibits inhibition angiotensin I II ACE endothelin 1 nitric oxide renin hypertension diabetes 2.545248618785
10010785 (±)-Lisofylline 6493-06-7 ≥98% 2009-09-18 17.697113259669 -lisofylline CT-1501R; BL 194; LSF pentoxifylline phosphatidic acids shock sepsis antiinflammatory anti-inflammatory insulin diabetes IL-12 IL-12 inhibits inhibitions inhibitors IFN-γ IFNγ β-cell cell 39476-38-5 151852-35-3 17.697113259669
80310 L-NIL (hydrochloride) 159190-45-1 >95% 25.587716390424 l-nil-hydrochloride selective nitric oxide synthases inhibitors inhibits iNOS inducible (2HCl) L-NIL·2HCl 25.587716390424
80320 L-NIO (hydrochloride) 36889-13-1 >95% 12.640184162062 l-nio-hydrochloride nitric oxide synthase inhibitors NOS NO 12.640184162062
80220 L-NNA 2149-70-4 >99% 10.329705340700 l-nna NG-nitro-L-Arginine; L-NG-Nitroarginine nitric oxide synthases inhibitors NOS inhibits 10.329705340700
10010338 Lovastatin 75330-75-5 >98% 2008-03-03 7.865388865278 lovastatin LDL-c cholesterol HMG-CoA reductase HMGCoA statins heart diseases CVD atherosclerosis HDL-c NF-kB NF-.kappa.B TNF-.alpha. apoptosis anti-cancer mevacor Altocor mevinolin inhibits inhibitors inhibition 7.865388865278
10010339 Lovastatin Hydroxy Acid (sodium salt) Exclusive - >98% ✓ 2008-03-04 8.833895027624 lovastatin-hydroxy-acid-sodium-salt atherosclerosis LDL cholesterol HMG-CoA reductase statin heart disease CVD LDL-c HDL HDL-c inhibitors inhibits inhibition 8.833895027624
81650 L-Sepiapterin 17094-01-8 >99% 5.505248618784 l-sepiapterin tetrahydrobiopterin pterin GTP cyclohydrolase inhibitors 5.505248618784
10010541 L-threo-Sphingosine C-18 25695-95-8 >98% 2008-01-22 24.646381215469 l-threo-sphingosine-c-18 D-erythro-sphingosine sphingolipids ceramides serines palmitoyltransferases protein kinases C cells proliferations cytoskeletal organization inhibitor inhibition inhibits PKCsSPTs 24.646381215469
10004161 Luteolin 491-70-3 >98% 2004-04-20 29.298607734806 luteolin lignans flavones flavanoids metalloproteinases plants polyphenolic perilla leaves soybeans inhibitors inhibits inhibition reticulocytes 15-LOs 15-LOX 15-lipoxygenases TNFalpha TNF.alpha. TNF-alpha TNF-.alpha. 29.298607734806
13341 LY364947 396129-53-6 ≥98% 2009-07-23 46.636381215470 ly364947 TGF-β RI Kinase Inhibitor; HTS 466284 TGF-β receptor inhibitors antagonists Smad p38 MAPK MLK-7 cells growth fibroblasts NIH 3T3 cells phosphorylation fibronectin PAI-1 uPA matrigel invasion MDA-MB-231 cells transforming factors LY 364947 LY-364947 HTS-466284 HTS466284 HTS 466284 ALK5 Inhibitor I TβR-I inhibitor Transforming Growth Factor-β Type I Receptor Kinase Inhbitor [3-(Pyridin-2-yl)-4-(4-quinoynyl)]-1H-pyrazole 46.636381215470
13174 M 344 251456-60-7 ≥98% 2009-07-24 55.830465776549 m-344 D237; Histone Deacetylase Inhibitor III; MS 344 HDACs inhibitors inhibits inhibitions histones deacetylases HDAC1 HDAC6 cancers squamous carcinoma radiation cells cycles arrest apoptosis endometrial ovarian M344 MS344 M-344 MS-344 55.830465776549
10010497 Manumycin A 52665-74-4 ≥98% 2008-06-25 19.969640883978 manumycin-a UCF 1C; NSC 622141 farnesyltransferase inhibitors inhibits inhibition cancer antitumor anti-tumor signal transduction Ras farnesylation NF-.kappa.B NF-kB NF-kappaB 19.969640883978
10009645 Maslinic Acid Exclusive 4373-41-5 >98% ✓ 2007-11-02 15.264751381216 maslinic-acid 2α-Hydroxyoleanoic Acid; Crategolic Acid cancer apoptosis antiproliferative antioxidant HIV inhibition inhibitor inhibits leukemia cells astrocytoma CaCo-2 colon HIV-1 aids 15.264751381216
70550 Meclofenamate (sodium salt) 6385-02-0 >99% 2.441215469612 meclofenamate-sodium-salt PPAR cyclooxygenases inhibitors NSAIDs COX-1 COX-2 nonsteroidal anti-inflammatory drugs cox1 cox2 pghs1 pghs2 pghs-1 pghs-2 prostaglandin H synthases synthase-1 synthase-2 inhibits peroxisome proliferator-activated receptors 2.441215469612
81020 MEG (sulfate) 3979-00-8 >98% 48.892011049723 meg-sulfate iNOS inducible nitric oxide synthases inhibitors peroxynitrite scavenger selective 2-mercaptoethyl-guanidine 48.892011049723
10624 Methylenedioxy Pyrovalerone Exclusive 687603-66-3 ≥98% ✓ 2011-01-07 41.186211080622 methylenedioxy-pyrovalerone MDPV 3,4-methylenedioxypyrovalerone inhibitors neurotransmitters dopamine norepinephrine MDMA ecstasy forensics designer drugs Hemihydrate Apomorphine Hydrochloride Anhydrous Apomorphine Hydrochloride Chloride Apomorphine Apomorphin Teclapharm Apomorphine Chloride Berberine Alkaloids Camptothecine Camptothecin Umbellatine Apomorphine Britaject Berberine Alkaloids Berbines Apokinon 41.186211080622
10679 Methylenedioxy Pyrovalerone-d8 (hydrochloride) 1246820-09-6 ≥99% deuterated product 2011-02-15 37.891464123511 methylenedioxy-pyrovalerone-d8-hydrochloride MDPV-d8 3,4-methylenedioxypyrovalerone inhibitors neurotransmitters dopamine norepinephrine MDMA ecstasy neuroscience forensics designer drugs deuterateds deuteriums GC/MS GC-MS LC/MS LC-MS mass spectrometry MS standards 37.891464123511
10684 Methylenedioxy Pyrovalerone (hydrochloride) 24622-62-6 ≥98% 2011-01-07 56.786631573859 methylenedioxy-pyrovalerone-hydrochloride MDPV 3,4-methylenedioxypyrovalerone inhibitors neurotransmitters dopamine norepinephrine MDMA ecstasy neuroscience forensics designer drugs 56.786631573859
10010252 Methyl-L-NIO (hydrochloride) 150403-96-6 >98% 2008-02-12 7.353508287293 methyl-l-nio-hydrochloride NOS L-arginine NO nitric oxide nNOS eNOS iNOS inhibitor inhibits inhibition vasodilation inflammation 7.353508287293
10010340 Mevastatin 73573-88-3 ≥98% 2008-07-16 15.453029465930 mevastatin Statin I; NSC 281245; L 637312; Compactin; ML 236B; CS 500 atherosclerosis cholesterol HMG-CoA reductases statins heart diseases CVD LDL-c LDLc HDL-c HDLc TNF-.alpha. TNF-a TNF-alpha NF-kb NF-.kappa.B NF-kappaB apoptosis cancers cardiovascular TNF.alpha. inhibtis inhibitor inhibition HMGCoA pythium ultimum 15.453029465930
13357 Milrinone 78415-72-2 ≥98% 2011-03-07 274.534618088485 milrinone Primacor®; WIN 47203 inhibitors phosphodiesterases PDE3A PDE3B cAMP vascular diseases cardiovascular effects Sanofi Synthelabo Brand of Milrinone Lactate Sanofi Winthrop Brand of Milrinone Lactate Sanofi Synthelabo Brand of Milrinone Sanofi Brand of Milrinone Lactate Lactate Milrinone Milrinone Lactate Win-47203 Win 47203 Milrinone Corotrope Win47203 Primacor Corotrop inhibits inhibition 274.534618088485
13208 Mirin 299953-00-7 ≥95% 2009-04-15 39.269558011050 mirin DNA damage ATM histone nuclease MRN Mre11 Rad50 Nbs1 repair 39.269558011050
13600 MK 0457 639089-54-6 ≥98% 2010-08-16 8.036187845304 mk-0457 Tozasertib; VX 680 mitosis aurora kinase inhibitors inhibits inhibition MK0457 MK-0457 MK-457 MK457 cells cycles cancers apoptosis tumor A B C MK 0457 VX-680 VX680 Piperazines 8.036187845304
10133 MK 886 (sodium salt) 118427-55-7 >99% 2004-06-11 73.983365080673 mk-886-sodium-salt guanylate cyclases inhibitors leukotrienes FLAP 5-LOs 5-LOX 5-lipoxygenases activating proteins inhibits inhibition mk886 mk-886 73.983365080673
10010236 ML-9 105637-50-1 ≥98% 2008-01-21 16.362486187845 ml-9 PKB Akt inhibitors inhibits inhibition serine/threonine kinase PKA P90S6 MAP kinases cancers anti-cancers insulin glucose transports calcium channels calmodulin intracellular smooth muscles asthma 16.362486187845
13284 MS-275 209783-80-2 ≥98% 2009-11-05 58.348134847554 ms-275 Entinostat; SNDX 275 inhibitors histone deacetylases HDACs HDAC1 HDAC3 HDAC8 cyclin-dependent kinase inhibitor 1A p21 CIP1 WAF1 cell growth differentiation tumors cancers apoptosis adriamycin PARP Hsp90 ms275 MS 27-275 SNDX-275 SNDX275 MS27275 58.348134847554
75770 MS-PPOH 206052-02-0 >98% 2007-02-23 19.478453038674 ms-ppoh CYP450 cytochromes epoxidase activity inhibitor inhibition inhibits microsomal enzymes endocrinology 19.478453038674
63150 Myriocin 35891-70-4 >98% 2007-05-03 49.891958256598 myriocin Thermozymocidin; ISP-1 serine palmitoyltransferase inhibitors sphingolipids antibiotic immunosuppressants inhibition inhibited atherosclerosis 49.891958256598
70272 N-(2-phenylethyl)-Indomethacin amide - ≥98% 12.448042620363 n-2-phenylethyl-indomethacin-amide N-2PIA aromatic amides inhibitors inhibits COX-2 COX2 PGHS2 PGHS-2 prostaglandin H synthases cyclooxygenases 12.448042620363
70274 N-(3-pyridyl)-Indomethacin amide - ≥98% 15.172194159431 n-3-pyridyl-indomethacin-amide N-3PyIA aromatic amides inhibitors inhibits COX-2 COX2 PGHS2 PGHS-2 prostaglandin H synthases cyclooxygenases COX-1 COX1 PGHS1 PGHS 1 15.172194159431
70278 N-(4-acetamidophenyl)-Indomethacin amide - ≥98% 14.522716390423 n-4-acetamidophenyl-indomethacin-amide N-4AIA aromatic amides inhibitors inhibits COX-2 COX2 PGHS2 PGHS-2 prostaglandin H synthases cyclooxygenases 14.522716390423
10017 N-Ac-Asp-Glu-Val-Asp-CHO 184179-08-6 >98% 2004-04-29 8.839571823204 n-ac-asp-glu-val-asp-cho Ac-DEVD-CHO Valinamide caspases caspase 3 inhibitors Yama ICE3 CPP32 Apopain inhibition inhibits selective apoptosis 8.839571823204
10008284 N-acetyl-2-carboxy Benzenesulfonamide Exclusive 849067-18-1 >98% ✓ 2006-05-10 12.068987108655 n-acetyl-2-carboxy-benzenesulfonamide analogs aspirin inhibits inhibitors inhibition cyclooxygenaes COX-1 COX-2 COX1 COX2 12.068987108655
10016 N-Ac-Tyr-Val-Ala-Asp-CHO 143313-51-3 >98% 2004-04-14 15.615607734806 n-ac-tyr-val-ala-asp-cho Ac-YVAD-CHO inhibitor inhibits apoptosis interleukins inhibition selective irreversible interleukin-1.beta.converting enzyme ICE Caspase-1-IL-1.beta. Il1beta neuroprotective cerebral ischemia alaninamides 15.615607734806
13055 Naphthofluorescein 61419-02-1 ≥98% 2009-03-20 0.670534069981 naphthofluorescein CCG 8295 furin matrix metalloproteinase MTA-MMP MMP2 motility invasion cancer metastasis MMP inhibitors naphthafluorescein 0.670534069981
13570 N-Benzylacetamidine (hydrobromide) 186545-76-6 ≥98% 2010-02-11 32.162348066299 n-benzylacetamidine-hydrobromide NO nitric oxide synthases NOS iNOS inflammation immune responses eNOS inhibitors inhibits inhibition inflammatory alpha-D-N-Acetyl-Galactosaminyloligosaccharidase alpha D N Acetyl Galactosaminyloligosaccharidase alpha-D-N-Acetylgalactosaminyloligosaccharidase alpha D N Acetylgalactosaminyloligosaccharidase endo-N-Acetyl-alpha-D-Galactosamidase endo N Acetyl alpha D Galactosamidase endo-alpha-N-Acetylgalactosaminidase endo alpha N Acetylgalactosaminidase N-Acetyl-alpha-D-Galactosaminidase N Acetyl alpha D Galactosaminidase alpha-N-Acetyl-D-galactosaminidase alpha N Acetyl D galactosaminidase alpha-N-Acetylgalactosaminidase alpha N Acetylgalactosaminidase alpha-Galactosidase B alpha Galactosidase B 32.162348066299
10584 (−)-Neplanocin A Exclusive 72877-50-0 ≥98% ✓ 2011-03-25 55.264554064720 -neplanocin-a S-adenosylhomocysteines hydrolases SAH inhibitors S-adenosylmethionines SAM methyltransferases antitumor antiviral cancer virus methylation Neplanocin A neplanocinA anti-tumor 55.264554064720
10554 NG-amino-L-Arginine (hydrochloride) - ≥97% 2010-09-16 6.789959819185 ng-amino-l-arginine-hydrochloride 57444-72-1 inhibitors inhibits inhibition nNOS iNOS eNOS nitric oxides synthesis BR labs BogaR 6.789959819185
10011250 NH125 278603-08-0 ≥95% 2008-11-21 5.868977900552 nh125 antibacterial histidine kinase cancer cell cycle eEF-2K drug resistance imidazoles 5.868977900552
10649 Niclosamide 50-65-7 ≥95% 2011-01-12 1.259751381215 niclosamide antihelminthic helminth tapeworms inhibitors STAT3 cancers proliferation anti-helminthic salicylanilide Du 145 DU145 DU-145 Niclosamide, 2-Aminoethanol (1:1) Aventis Brand of Niclosamide Bayer Brand of Niclosamide Clonitralide Niclosamide Bayluscide Bayer 2353 Trédémine Niclocide Radewerm Phenasal Bayer 73 Yomesan Fenasal 1.259751381215
70650 Niflumic Acid 4394-00-7 >99% 45.572438831886 niflumic-acid UP83; Nifluril; Donalgin; Actol selective inhibitors COX-2 PGHS-2 prostaglandins H Synthase 2 acids cyclooxygenase 45.572438831886
10010422 Nilotinib 641571-10-0 ≥98% 2009-10-23 33.306325966850 nilotinib AMN107 tyrosine kinases inhibitors therapy cancer Bcr/Abl chronic myeloid leukemia MLL philadelphia chromosomes acute lymphoblastic ALL imatinib gleevec genes expression DNA helicase complex cyclins cyclin-dependent cells proliferation 33.306325966850
70640 Nimesulide 51803-78-2 >99% 51.709812154696 nimesulide R805 selective inhibitors COX-2 PGHS-2 synthases prostaglandins R-805 cyclooxygenases inhibits 51.709812154696
13692 Nitazoxanide 55981-09-4 ≥95% 2010-08-11 3.881160220994 nitazoxanide NTZ; NSC 697855 antiparasitics Giardia Cryptosporidium tuberculosis inhibitors inhibits inhibition PH 6776 alinia BRN 1225475 cryptaz NTZ anti-parasitics Thiazoles 3.881160220994
10004971 N,N'-Dicyclohexylurea 2387-23-7 ≥98% 2010-03-17 16.488798342541 n-n-dicyclohexylurea DCU; NSC 17013 hypertension Epoxyeicosatrienoic acids EETs soluble epoxide hydrolase sEH inhibitors inhibits inhibiting PPARα 1,3-dicyclohexylurea dicyclohexylcarbodiamide Doms-Adrian Brand of Alanine Doms Adrian Brand of Alanine Alanine Doms-Adrian Brand Alanine, L-Isomer Alanine, L Isomer L-Isomer Alanine L-Alanine L Alanine Alanine Abufène 16.488798342541
11040 Nodinitib-1 New 799264-47-4 ≥95% 2012-01-20 81.298793738490 nodinitib-1 ML130; CID-1088438 NOD1 NLR innate immunity NF-κB signaling inflammation MAPK inflammatory diseases inhibitors inhibition inhibits NACHT leucine proteins bacterial bacteria ligands stress kinases interferons polymorphisms genes asthma bowel multiple sclerosis MS cells CD83 CD86 HLA-DR IL-1β IL-6 TNFα 81.298793738490
10005705 NO-Indomethacin Exclusive 301838-28-8 >98% ✓ 2004-10-20 6.229944751381 no-indomethacin NCX 2121 inhibition inhibitors NSAIDs non-steroidal anti-inflammatory drugs inhibits nitric oxides cancer chemopreventative donor gastrointestinal NOs PaCa-2 PaCa2 pancreatic analgesic 6.229944751381
10115 N-Oleoyl Dopamine 105955-11-1 >98% 6.968823993686 n-oleoyl-dopamine ODA VR1 agonists CB1 receptors analogs vanilloids cannabinoids analgesic amides N-oleoyldopamine inhibits inhibitors inhibition 5-lipoxygenases 5-LOs binding selective FAAH hydrolases fatty acid neurochemistry neuroscience cbs synthetic 6.968823993686
70300 Nordihydroguaiaretic Acid 500-38-9 >95% 22.350773480662 nordihydroguaiaretic-acid NDGA lipoxygenases inhibitors inhibits NDGA cyclooxygenase 22.350773480662
10006861 nor-NOHA 189302-40-7 >97% 2007-07-13 29.670000000000 nor-noha Nω-hydroxy-nor-Arginine spibio spi-bio buffers rat liver inhibitor inhibitors murine macrophags cells nitric oxides arginases 29.670000000000
81600 NS-2028 204326-43-2 >99% 22.137430939226 ns-2028 specificity inhibitors guanylyl cyclase NS2028 guanylate cyclic cGMP inhibits 22.137430939226
70590 NS-398 123653-11-2 >98% 105.368845917740 ns-398 cyclooxygenases inhibitors NSAIDs COX-2 nonsteroidal anti-inflammatory drugs cox2 pghs2 pghs-2 prostaglandins synthases synthase-2 inhibits selective ns398 selectivity neurochemistry 105.368845917740
10011255 NSC 210902 51726-83-1 ≥95% 2008-09-15 4.363314917128 nsc-210902 Inhibitor inhibits inhibition CK2 kinase cell signaling apoptosis cancers NSC210902 4.363314917128
13196 NSC 23766 (hydrochloride) 1177865-17-6 ≥98% 2010-07-20 18.902101493759 nsc-23766-hydrochloride 733767-34-5 GTPases cells cycles growth proliferations cell-cell adhesions motility differentiation guanine nucleotides exchange factors GEFs inhibitors inhibits inhibition cell migration Aminoquinolines angiogenesis leukemia cancers gene expression Rac1 Inhibitor 18.902101493759
13303 NSC 663284 383907-43-5 ≥98% 2010-04-01 14.200414364641 nsc-663284 Cdc25 Phosphatase Inhibitor II; DA-3003-1 dual specificity phosphatases CDC25 Cdc25A Cdc25B Cdc25C proto-oncogenes cancers inhibitors VHR PTP1B MKP-1 Cdk1 Cdk2 cells proliferation tumors inhibits inhibition Cdcs potent cell-permeable irreversible 14.200414364641
13308 NU 7026 154447-35-5 ≥95% 2009-09-21 33.867375690607 nu-7026 DNA-PK Inhibitor II; LY293646 DNA-dependent proteins kinase DNA-PK strand breaks ionizing radiation DNA repair inhibitors inhibitis inhibitions PI3K ATM ATR PAPR-1 PARP1 cytotoxicity topoisomerase II leukemia mitoxantrone NU-7026 NU 7026 ataxia telangiectasia mutated Rad3 related Rad3-related Rad 3 Rad-3 DNA-Dependent Protein Kinase 33.867375690607
18585 (−)-Nutlin-3 - ≥98% 2008-08-06 213.659815837938 -nutlin-3 Nutlin 3a P53 cellular stress proliferation cells cycle apoptosis tumor suppressor MDM2 agents Nutlin-3 enantiomer a 213.659815837938
10009816 (+)-Nutlin-3 - ≥98% 2008-08-11 96.811767955801 -nutlin-3 Nutlin 3b p53 cellular stress proliferation cells cycle apoptosis tumer suppressor MDM2 inactive inhibitors inhibits inhibition Nutlin-3 enantiomer b 96.811767955801
13641 NVP-AEW541 (hydrochloride) - 98% 2010-07-28 41.811016574586 nvp-aew541-hydrochloride 475488-34-7 IGF-1R Insulin-like growth factor I receptors tyrosine kinases angiogenesis cells proliferation cancers inhibitors inhibition inhibits 701294-63-5 Ins-R NWT-21 Pyrroles 41.811016574586
10565 NVP-BEZ235 915019-65-7 ≥98% 2010-10-12 41.065404920432 nvp-bez235 phosphatidylinositols 3-kinases PI3Ks Akt/PKB mTORs cancers inhibitors inhibits inhibition angiogenesis genes expressions apoptosis differentiation rapamycin phosphatidyls inositols phosphatidylinositols-3-kinase Imidazoles BEZ235 41.065404920432
70263 O-Acetyl Salicylhydroxamic Acid - >98% 20.136926795580 o-acetyl-salicylhydroxamic-acid O-ASHA; AcSHA cyclooxygenases inhibitors COX-1 COX-2 cox1 cox2 pghs1 pghs-1 pghs-2 prostaglandin synthases inhibits nonselective irreversible pghs2 20.136926795580
10010547 O-Arachidonoyl Glycidol Exclusive 439146-24-4 >98% ✓ 2008-03-31 18.812883977900 o-arachidonoyl-glycidol 2-AG 2-arachidonoyl glycerol 2-oleoylglycerol N-arachidonoylethanolamine anandamide AEA FAAH endocannabinoid obesity pain neurodegenerative diseases monoacylglycerol lipase inhibits inhibitors inhibitions MAGL MGL cannabinoids 18.812883977900
81410 ODQ 41443-28-1 >98% 26.769889502762 odq soluble guanylyl cyclase inhibitors guanylate cyclase NO nitric oxide sGC hypoxia 26.769889502762
10010299 Oleoyl 3-carbacyclic Phosphatidic Acid Exclusive - ≥95% ✓ 2009-10-14 14.945676795580 oleoyl-3-carbacyclic-phosphatidic-acid 3-ccPA 18:1 cyclic phosphatidic acids cPAs lysophosphatidic LPA ccPA 3ccPA oleate transcellular migration MM1 cells mesothelial autotoxin cancer survival growth migration invasion metastasis antagonist LPA1 LPA2 LPA3 476310-24-4 14.945676795580
9000629 Oleoyl Serotonin Exclusive 1002100-44-8 ≥98% ✓ 2010-05-18 5.339305445935 oleoyl-serotonin N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA Hydrolase Long-Chain Fatty-Acyl-CoA Fatty-Acyl-CoA Hydrolase Long-Chain Long-Chain Fatty-Acyl-CoA Hydrolase Long Chain Fatty Acyl CoA Hydrolase Palmitoyl Coenzyme A Hydrolase Acylhydrolase Oleoyl-CoA Thioesterase Fatty Acyl Oleoyl-CoA Acylhydrolase Oleoyl CoA Acylhydrolase Hydrolase Palmitoyl-CoA Deacylase, Palmitoyl CoA CoA Deacylase, Palmitoyl Thioesterase, Palmitoyl Palmitoyl-CoA Hydrolase Palmitoyl CoA Hydrolase Palmitoyl CoA Deacylase Hydrolase Stearoyl CoA Fatty Acyl Thioesterase CoA Hydrolase Stearoyl Stearoyl CoA Hydrolase Palmitoyl Thioesterase Hydrolase Acyl CoA CoA Hydrolase Acyl Acyl CoA Hydrolase Thioesterase I 5.339305445935
9000694 Oleoyl Serotonin-d17 Exclusive - ≥99% deuterated product ✓ 2010-09-27 5.120520915548 oleoyl-serotonin-d17 N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA deuterateds deuteriums MS mass spectrometry GC-MS LC-MS GC/MS LC/MS standards 5.120520915548
70560 Oleyloxyethyl Phosphorylcholine 84601-19-4 >98% 20.989889502762 oleyloxyethyl-phosphorylcholine phospholipase inhibitors 20.989889502762
10010240 Olomoucine 101622-51-9 >98% 2007-09-13 11.602888713496 olomoucine inhibitors inhibits inhibition cyclin-dependent kinases cdks spinal cord injury SCI G1 cell cycle 11.602888713496
10005426 Orlistat 96829-58-2 98% 2010-03-30 20.997096378146 orlistat Xenical; Tetrahydrolipstatin; Alli DAGL 2-AG obesity gastric pancreatic lipases carboxyl esters inhibitors GIP 111397-16-1 GLP-1 anti-obesity antiobesity CCK PP inhibition inhibited GLP 1 GLP1 diacylglycerol Leucine, L-Isomer Leucine L Isomer L-Isomer Leucine L-Leucine Leucine 20.997096378146
13804 OU749 519170-13-9 ≥95% 2010-07-20 1.839779005525 ou749 γ-Glutamyl transferases γ-glutamyl transpeptidases glutathione markers liver dysfunction alcohol abuses biomarkers diabetes cardiovascular diseases cancers acivicin OU-749 OU 749 Mixtures Sulfonamide Sulfonamide Mixtures Sulfonamides 1.839779005525
13521 Oxalomalic Acid (sodium salt) 89304-26-7 ≥95% 2010-02-05 54.207527624310 oxalomalic-acid-sodium-salt aconitases citric acids glutamate oxidative injuries inhibitors inhibition inhibits oxalomalics oxaloacetate glyoxylate iron regulatory proteins IRP Oxalate Monohydrogen Monopotassium Monohydrogen Monopotassium Oxalate oxalates 54.207527624310
13176 Oxamflatin 151720-43-3 ≥95% 2010-11-16 52.416104972376 oxamflatin Metacept 3 HDACs histones deacetylases genes expressions morphology motility apoptosis cells cycles cancers reducing reduction proliferation Acids Hydroxamic Hydroxamic Acids Acid Hydroxamic Hydroxamic Acid 52.416104972376
70515 Ozagrel 82571-53-7 >98% 0.656629834254 ozagrel OKY-046 thromboxanes synthases inhibitors inhibits imidizoles TXAs antihypertensive inhibition atherosclerosis 0.656629834254
10010298 Palmitoleoyl 3-carbacyclic Phosphatidic Acid Exclusive 910228-13-6 ≥95% ✓ 2009-11-03 12.582146196344 palmitoleoyl-3-carbacyclic-phosphatidic-acid 3-carbacyclic PA; 3-ccPA 16:1 cyclic phosphatidic acids cPAs lysophosphatidic LPA ccPA 3ccPA palmitoleate transcellular migration MM1 cells mesothelial autotoxins cancer survival growth migration invasion metastasis NPP2 ENPP2 ectonucleotide pyro phosphatase/phosphodiesterase 2 12.582146196344
10010293 Palmitoyl 3-carbacyclic Phosphatidic Acid Exclusive 476310-22-2 ≥95% ✓ 2009-10-07 15.891406328478 palmitoyl-3-carbacyclic-phosphatidic-acid 3-ccPA 16:0 cyclic acids cPAs lysophosphatidic LPA ccPA 3ccPA palmitate transcellular migration MM1 cells mesothelial autotoxins cancers survival growth migration invasion metastasis 15.891406328478
9000630 Palmitoyl Serotonin Exclusive 212707-51-2 ≥98% ✓ 2010-05-18 5.471902131018 palmitoyl-serotonin N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA Hydrolase Long-Chain Fatty-Acyl-CoA Fatty-Acyl-CoA Hydrolase Long-Chain Long-Chain Fatty-Acyl-CoA Hydrolase Long Chain Fatty Acyl CoA Hydrolase Palmitoyl Coenzyme A Hydrolase Acylhydrolase Oleoyl-CoA Thioesterase Fatty Acyl Oleoyl-CoA Acylhydrolase Oleoyl CoA Acylhydrolase Hydrolase Palmitoyl-CoA Deacylase Palmitoyl CoA CoA Deacylase Palmitoyl Thioesterase Palmitoyl Palmitoyl-CoA Hydrolase Palmitoyl CoA Hydrolase Palmitoyl CoA Deacylase Hydrolase Stearoyl CoA Fatty Acyl Thioesterase CoA Hydrolase Stearoyl Stearoyl CoA Hydrolase Palmitoyl Thioesterase Hydrolase Acyl CoA CoA Hydrolase Acyl Acyl CoA Hydrolase Thioesterase I 5.471902131018
10011133 Papaverine 58-74-2 ≥98% 2009-02-09 4.709079189687 papaverine NSC 136630 phosphodiesterase cAMPs vasospasm erectile dysfunction inhibitors inhibits inhibition papervin 4.709079189687
13034 PD 0325901 391210-10-9 ≥98% 2009-03-13 51.778168546128 pd-0325901 MEK ERK RAS RAF MAPK tumors stem cells cancers differentiation signaling GSK3 kinase inhibitors inhibits inhibition pd325901 pd 325901 PD0325901 51.778168546128
10010518 PD 146176 4079-26-9 ≥98% 2009-02-25 31.652648041431 pd-146176 NSC 168807 atherosclerosis 15-LOs 15-lipoxygenases oxidant injury injuries apoptosis amyloid β proteins inhibitors inhibits inhibitions Alzheimers disease oxidative stress pd146176 31.652648041431
9000988 PD 166326 New 185039-91-2 ≥98% 2011-11-30 100.167394485229 pd-166326 inhibitors cancers c-abl c-src Bcl/Abl tyrosine receptors kinases cells signaling leukemia CML chronic myelogenous leukemia PD-166326 PD166326 pyridopyrimidine STI571 mesylate 100.167394485229
13032 PD 173074 219580-11-7 ≥98% 2009-07-29 50.597762456167 pd-173074 fibroblast growths factors receptors FGFRs FGFR1 tyrosine kinase activity activities activation signals propagation inhibitors inhibition inhibits autophosphorylation PDGFR c-Src cSrc c Src EGFR InsR MEK PKC FGFR2 FGFR3 FGFR4 FGFR5 angiogenesis cancers tumors self-renewal self renewal stems cells ERK1/2 ERK-1/2 ERK 1/2 50.597762456167
10012431 PD 184161 Exclusive 212631-67-9 ≥98% ✓ 2009-06-09 35.417814273821 pd-184161 MEK inhibitors MAP kinase ERK signaling cancer MEK 1/2 inhibition inhibited ERK 1/2 potent selective pd184161 35.417814273821
13279 PF-3845 1196109-52-0 ≥98% 2010-01-27 37.992885205648 pf-3845 fatty acids hydrolase FAAH N-acyl ethanolamines NAEs endocannabinoids N-arachidonoyl ethanolamine anandamide AEA inhibitors inhibits inflammation pain PF3845 PF 3845 cannabinoids cbs synthetic Antibodies Monoclonal Monoclonal Antibodies 37.992885205648
10010908 PF-750 959151-50-9 >98% 2008-03-25 11.288732734806 pf-750 FAAH inhibitors inhibits inhibition cannabinoids depression anxiety inflammation pain neurochemistry 11.288732734806
70400 Phenylbutazone 50-33-9 >99% 4.443583267560 phenylbutazone cyclooxygenases inhibitors NSAIDs COX-1 COX-2 nonsteroidal anti-inflammatory drugs cox1 cox2 pghs1 pghs2 pghs-1 pghs-2 prostaglandin H synthases synthase-1 synthase-2 inhibits PGIS 4.443583267560
10735 Phthalazinone pyrazole Exclusive 880487-62-7 ≥98% ✓ 2011-07-27 2.012523020258 phthalazinone-pyrazole inhibitors inhibits inhibition auroras kinases cells cycle cancers centrosomes mitosis spindles cancers proliferation cells growth phosphorylation Auroroa-A Aurora-B Aurora-C A B C HCT116 HCT-116 Colo 116 HCT 116 Colo116 Colo-116 MCF7 MCF-7 MCF 7 2.012523020258
10010177 PI3-Kinase α Inhibitor 2 Exclusive 371943-05-4 >98% ✓ 2007-08-02 27.583552911176 pi3-kinase-inhibitor-2 PI3Kα Inhibitor 2; Phosphatidylinositol 3-Kinase α Inhibitor 2 phosphoinositides 3-kinases PI3-kinase phosphatidylinositols cancers proliferations inhibits inhibitors inhibition PI3-K PI3K inhibitory A375 melanoma cell proliferation 27.583552911176
13326 Pifithrin-α 63208-82-2 ≥95% 2009-07-16 31.221263812155 pifithrin p53 apoptosis DNA damage cyclin D1 C8 cells HUVECs endothelial cells dependent independent inactivator 31.221263812155
10748 Pifithrin-μ 64984-31-2 ≥98% 2011-06-20 17.587941988950 pifithrin PFT-μ; 2-Phenylethynesulfonamide p53 apoptosis Bcl-xL Bcl-2 mitochondria inhibitors nutlin heat shock proteins 70 HSP70 PES PAS pifithrin-mu pifithrin mu PFTμ PFTu 2-phenylacetylenylsulfonamide 2-phenylacetylenesulfonamide BclxL Bc12 17.587941988950
10009210 PIK-75 372196-67-3 ≥98% 2010-03-10 16.997085716132 pik-75 p110α PI3K insulin signaling signals cancers inhibitors inhibits inhibition signalling p110a phosphatidylinositol 3-kinase phosphorylation Akt activation mTORC1 PIP2 PIP3 p110β p110α p110γ p110beta p110 alpha p110.beta. p110.alpha. p110gamma p110.gamma.p110g Mixtures, Sulfonamide Sulfonamide Mixtures Sulfonamides 16.997085716132
13212 Pimelic Diphenylamide 106 Exclusive 937039-45-7 ≥98% ✓ 2009-09-30 25.076336144227 pimelic-diphenylamide-106 inhibitors inhibits inhibitions class I histone deacetylases HDACs SAHA HDAC1 HDAC2 HDAC3 HDAC8 II HDAC4 HDAC5 HDAC7 benzamides friedrich ataxia huntington disease 25.076336144227
13368 Piroxicam 36322-90-4 ≥95% 2010-01-06 17.139206349206 piroxicam NSC 666076; Larapam; Feldene inflammation NSAIDs inhibitors cyclooxygenases COX-1 COX-2 analgesic pain arthritis cancers Artrooxicam Baxo Bruxicam CP 16171 Geldene Neoxicam Reudene Roxicam Roxiden Sasulen Solocalm Uphaxicam Zunden inhibition inhibited inflammatory Piroxicam CP-16171 CP 16171 Feldene CP16171 17.139206349206
10728 PIT-1 Exclusive 53501-41-0 ≥98% ✓ 2011-03-25 14.824756906077 pit-1 PIP3 PtdIns-(3,4,5)-P3 PH domains cancers inhibitors Akt PDK1 PTENs proteins binding pituitary-specific transcription factors pit-1 pituitary-specific pit 1 GHF-1 GHF 1 pit-oct-unc pit oct unc POU growth hormones 14.824756906077
10459 PKC 412 120685-11-2 ≥98% 2010-07-27 31.461705033762 pkc-412 CGP 41251; N-Benzoylstaurosporine; Midostaurin; CGP 41231 inhibitors inhibits inhibition PKC412 PKC-412 serine/threonine serine threonine tyrosines kinases PKCα PKCβ PKCγ PKC-α PKC-β PKC-γ Syk Flk-1 Flk1 Akt PKA c-Kit cKit C-Fgr cFgr FLT3 FLT-3 PDFRβ PDFR-β VEGFR1 VEGF2 nitric oxide synthase eNOS apoptosis cancers angiogenesis signal transduction Staurosporine 31.461705033762
13198 PP2 172889-27-9 ≥98% 2010-09-20 30.762276243094 pp2 AGL 1879 PTK inhibitors inhibits inhibition Src kinase T cells T-cells enzymes AG1879 AG 1879 PP-2 PP 2 signalling tyrosine kinases tyrosine focal Tyr 577 adhesion kinases AG-1879 AGL1879 AGL 1879 thaliana Proteins Arabidopsis Proteins Arabidopsis thaliana Arabidopsis thaliana Proteins Hemagglutinins Plant Thale Cress Proteins Plant Hemagglutinins Arabidopsis Proteins Agglutinins Plant Plant Agglutinins Proteins Plant Phytagglutinins Plant Proteins Lectins Plant Plant Lectins 30.762276243094
13643 PP242 1092351-67-1 ≥95% 2011-04-22 23.734631237393 pp242 mTORs mTORC1 mTORC2 inhibitors cancer leukemia rapamycin PP 242 PP-242 inhibited inhibition 23.734631237393
13327 PPM-18 65240-86-0 ≥95% 2010-09-15 8.838674033149 ppm-18 NSC 73233 inhibitors inhibits inhibition NF-κB NFκB NF κB NF-kB NFkB kB iNOS inflammation sepsis inducible nitric oxides synthases inflammatory NO Naphthalenediones Naphthoquinones Naphthazarins 8.838674033149
75760 PPOH 206052-01-9 >99% 46.286924493554 ppoh selective epoxygenases inhibitors inhibits acetylenic fatty acids cytochromes CYP450-4A2 CYP450-4A3 CYP450-4A1 CYP-450-4A2 CYP-450-4A3 CYP-450-4A1 CYP-4A2 CYP-4A1 CYP-4A3 endocrinology 46.286924493554
10010343 Pravastatin (sodium salt) 81131-70-6 >98% 2008-03-04 12.052805840568 pravastatin-sodium-salt atherosclerosis HMGCoA HMG-CoA reductase LDL-c HDL-c statins cholesterol heart diseases CVD pravachol lipostat inhibitors inhibits inhibitions cardiovascular 12.052805840568
13621 Pristimerin Exclusive 1258-84-0 ≥98% ✓ 2010-03-08 42.875840568271 pristimerin Celastrol methyl ester; NSC 99281 monoacylglycerol lipases MAGLs monoglycerol MGLs cannabinoids 2-arachidonoyl glycerol 2-AG inhibitor 2-Picenecarboxylic acids cannabinoids cbs synthetic Triterpenes 42.875840568271
10011724 Propenyl-L-NIO (hydrochloride) Exclusive - >90% ✓ 2008-08-19 5.421243093922 propenyl-l-nio-hydrochloride ENIPO nitric oxide synthase NOS iNOS selective inhibitors inhibits inhibition 5.421243093922
13527 Pseudolaric Acid B 82508-31-4 ≥98% 2009-12-04 9.385994475137 pseudolaric-acid-b PAB Pseudolarix kaempferi traditional Chinese fungal fungus infections cancers apoptosis angiogenesis tumors inhibits inhibitors inhibition P. therapy apoptosis cells 9.385994475137
10817 Pyrovalerone Exclusive 3563-49-3 ≥95% ✓ 2011-05-25 40.680014376032 pyrovalerone Thymergix; Centroton; Valerophenone inhibitors neurotransmitters dopamine norepinephrine controlled substances forensic analysis forensics bath salts 10836 valerophenone 40.680014376032
10836 Pyrovalerone (hydrochloride) 1147-62-2 ≥95% 2011-05-24 45.364385875727 pyrovalerone-hydrochloride Centroton; Thymergix inhibitors neurotransmitters dopamine norepinephrine controlled substances forensic analysis forensics bath salts inhibition 10817 free base inhibits 3563-49-3 45.364385875727
13294 Pyrrophenone 341973-06-6 ≥90% 2010-04-07 51.947504688529 pyrrophenone phospholipase A2 group IVA phospholipase A2 PLA2 cytosolic PLA2 cPLA2 arachidonic acid AA prostaglandins PG leukotrienes LT inhibitors PGE2 LTB4 blood secretory type PLA2 sPLA2 inflammation inhibition inhibits inflammatory Pyrrolidines 51.947504688529
10006734 QNZ 545380-34-5 >98% 2005-12-16 36.888639502762 qnz CAY10470 inhibits inhibitor inhibition NF kB NF-kB NF-.kappa.B nuclear factors transcription proinflammatory cytokines TNFa TNF.alpha. interleukins IL-1b IL-1.beta. IL-6 IL-8 activation Jurkat cells LPS lipopolysaccharides murine splenocytes in vivo edema carrageenin rat hind paw NF-kappaB nfkb nf-kb NF-.kappa.B 36.888639502762
9000336 (R)-(+)-Acenocoumarol 66556-77-2 ≥98% 2009-06-25 4.986364640884 -r-acenocoumarol (R)-(+)-Nicoumalone; (R)-(+)-Acenocoumarin thrombosis vitamin k warfarin bleeding blood coagulation inhibitors anticoagulants G-23350 Sintrom Sinthrome coumarins 4.986364640884
13089 Radicicol 12772-57-5 ≥98% 2009-02-24 8.378839779005 radicicol Monorden; NSC 294404; KF9-A; KF58332 Hsps antibiotic antifungal antimalarial inhibitors inhibits inhibition heat shock proteins 90 Hsp90 topoisomerase radisicol R 2146 NSC-294404 NSC294404 Monordene KF9A KF 58332 KF-58332 KF-9A 8.378839779005
13346 Rapamycin 53123-88-9 ≥95% 2009-10-21 71.548611281632 rapamycin Sirolimus immunosuppresssants transplants rejection inhibitors IL-2 lymphocytes B cells T FKBP12 mTOR mTORC1 cancer adipogenesis diabetes tuberous sclerosis cardiovascular diseases 71.548611281632
13900 Resveratrol-3-O-Sulfate 553662-69-4 ≥98% 2011-06-01 27.570370955011 resveratrol-3-o-sulfate polyphenol phytoalexin biochemicals physiological actions estrogenic antiplatelet anti-inflammatory piceid polydatin grape juices glucuronidated metabolites humans 27.570370955011
70255 (R)-Flurbiprofen 51543-40-9 ≥99% 2004-06-11 5.745256511444 -r-flurbiprofen E-7869; Tarenflurbil; Flurizan cyclooxygenases inhibitors NSAIDs COX-1 COX-2 nonsteroidal anti-inflammatory drugs cox1 cox2 pghs1 pghs2 pghs-1 pghs-2 prostaglandin H synthases synthase-1 synthase-2 inhibits inhibition neurochemistry 5.745256511444
10010309 RG-13022 149286-90-8 >98% 2008-01-24 2.561519337016 rg-13022 protein tyrosine kinase PTK inhibitors inhibits inhibition antiproliferatives tyrphostin epidermal growth factors EGFs receptors cancers 2.561519337016
10010310 RG-14620 136831-49-7 >98% 2008-02-08 2.255949851253 rg-14620 protein tyrosine kinases PTKs inhibitors inhibits inhibition antiproliferative tyrphostin epidermal growth factors EGFs receptors proliferation cancers 2.255949851253
13293 Rhapontigenin Exclusive 500-65-2 ≥98% ✓ 2009-11-10 28.590690607734 rhapontigenin resveratrols antioxidants cancers cytochromes P450 CYP450 proliferation anti cancers anti-oxidants 28.590690607734
13616 (R)-Lisofylline 100324-81-0 ≥98% 2010-05-27 1.784944751381 -r-lisofylline (R)-LSF; (-)-Lisofylline pentoxifylline phosphatidic acid shock sepsis anti-inflammatory IFN-γ IL-12 β-cell insulin diabetes interleukins 12 IL IFN-gamma 1.784944751381
10311 (R)-(−)-Mellein New 480-33-1 ≥98% 2012-01-13 68.888888888889 -r-mellein Ochracin antibacterial antimalarial antifungal anticancer dihydroisocoumarin A. ochraceus wilhelm proliferation humans breasts cancers melanoma cells 21499-22-9 isocoumarin R-mellein MCF-7 MDA-MB-468 SK-MEL-28 (R)-mellein malme-3M 68.888888888889
13697 (R)-MG132 Exclusive 1211877-36-9 ≥98% ✓ 2010-06-22 93.183756906077 -r-mg132 ubiquitin proteasomes inhibitors proteolytic degradation inflammation cells cycle regulation cancers NF-κB apoptosis inhibition inhibited 93.183756906077
13300 Ro 31-6045 113963-68-1 ≥98% 2009-07-28 4.563674033149 ro-31-6045 Bisindolylmaleimide V PKC kinase inhibitors S6K mitogen-stimulated proteins p70 p85 protein kinases C 4.563674033149
13333 Ro 31-7549 (acetate) 138516-31-1 98% 2009-07-30 25.279844076120 ro-31-7549-acetate Bisindolylmaleimide VIII, acetate PKC isozyme inhibitors phospholipases cells signalling signaling SH-SYSY neuroblastoma 125313-65-7 inhibits inhibitions 25.279844076120
13334 Ro 31-8220 (mesylate) 138489-18-6 98% 2009-10-28 31.480915899324 ro-31-8220-mesylate Bisindolylmaleimide IX bisindolylmaleimide inhibitor protein kinase C PKC PKC-α PKC-βI PKC-βII PKC-γ PKC-ε PKA CaM kinase II glycogen synthase kinase-3 GSK-3 Ro318220 GSK3 125314-64-9 Ro-31-8220 75-75-2 31.480915899324
10011132 Rolipram 61413-54-5 ≥98% 2008-12-16 11.821048563680 rolipram ZK 62711; SB 95952 inhibits inhibitor inhibition phosphodiesterase PDE4 cAMP inflammation leukocyte LPS TNF monocytes C5a LTC4 eosinophil neurons bones loss 11.821048563680
10009569 (R)-Roscovitine 186692-46-6 >98% 2007-09-04 13.673075506446 -r-roscovitine Seliciclib cell cycle cyclin-dependent kinase cdk proliferation cancer renal disease 13.673075506446
13343 RSC-3388 337307-06-9 ≥95% 2010-02-15 11.178298950783 rsc-3388 cytosolic phospholipases A2 cPLA2 cPLA2α arachidonic acids eicosanoids platelet-activating factors PAF inhibitors inhibits inhibition inflammation dermatitis acrylamides 11.178298950783
9001095 (S)-2-Diphenylmethylpyrrolidine (hydrochloride) New 188398-87-0 ≥98% 2011-12-02 90.111953773925 -s-2-diphenylmethylpyrrolidine-hydrochloride (S)-Desoxy-D2PM NMR analysis dopamine transporter inhibitors stimulants psychoactive forensics 119237-64-8 inhibits inhibition desoxypipradrol 2-diphenylmethylpiperidine 90.111953773925
13664 S32826 1096770-84-1 ≥98% 2010-06-18 27.989850828728 s32826 Autotaxins lysophospholipase D lysophosphatidylcholine lysophosphatidic acids LPAs inhibitors src phosphatase 1B adipocytes plasma inhibited inhibition inhibits Esters, Phosphonic Acid Phosphonic Acid Esters Phosphonic Acids Phosphonates 27.989850828728
9000337 (S)-(−)-Acenocoumarol 66556-78-3 ≥98% 2009-06-25 4.986364640884 -s-acenocoumarol (S)-(-)-Nicoumalone; (S)-(-)-Acenocoumarin thrombosis vitamin k warfarin bleeding blood coagulation inhibitors inhibition inhibits sintrom sinthrome G-23350 G23350 4.986364640884
10009929 SAHA 149647-78-9 >98% 2007-08-07 164.175228067366 saha Vorinostat; Suberoylanilide Hydroxamic Acid; Zolinza™ HDACs inhibitors cancers inhibits inhibition 164.175228067366
13178 Salermide 1105698-15-4 ≥98% 2009-04-27 20.206550907655 salermide Sirtuin SIRT1 SIRT2 inhibitors cancers apoptosis leukemias histone deacetylases HDACS inhibition inhibited 20.206550907655
13628 Salidroside 10338-51-9 ≥97% 2010-05-28 12.325948434623 salidroside Rhodioloside glycosides plants Rhodiola Chinese medicine memory infections inflammation cancers diabetes fatigue apoptosis Glucosides 12.325948434623
13579 Salinomycin (sodium salt) 55721-31-8 ≥90% 2011-03-14 8.068784530387 salinomycin-sodium-salt cancers stem cells breasts inhibitors tumors anticancer pyrans anti-cancer inhibited inhibits inhibition CSCs 8.068784530387
10949 Sampling Tubes with PHMB - 2011-06-01 87.314364640884 sampling-tubes-with-phmb 4-(hydroxymercuri)Benzoic Acid spi-bio spibio tubes sampling PHMB inhibitors inhibits cystein protease cystein-protease thiol-specific thiol specific blocker blocking blocks EIA kits serines peptides biomarkers 87.314364640884
13067 SB 203580 152121-47-6 ≥98% 2009-01-14 24.842464088398 sb-203580 RWJ 64809; PB 203580 MAPKs signal transduction p38 kinases cytokines inflammation immune response PI3-kinase PDK1 apoptosis inhibitors inhibits inhibition sb203580 24.842464088398
13344 SB 203580 (hydrochloride) 869185-85-3 ≥98% 2009-09-08 15.798895027624 sb-203580-hydrochloride PB 203580 (hydrochloride); RWJ 64809 (hydrochloride) inhibitors inhibits inhibitions MAPK signal transduction p38 kinase PI3 PDK1 15.798895027624
10010246 SB 216763 280744-09-4 ≥98% 2008-06-11 12.182665745856 sb-216763 inhibitors inhibits inhibition GSK-3 GSK3 PI3K glycogen synthase kinase-3 sb216763 12.182665745856
13336 SB 225002 182498-32-4 ≥95% 2009-07-08 42.237320441988 sb-225002 CXCR2 IL-8RB IL-8 CXCL8 Gro-α CXCL1 inflammation chemokines neutrophils angiogenesis inhibitors colitis chemotaxis IL8 IL8RB Groα inhibition inhibits sb225002 42.237320441988
10096 SB 242084 (hydrochloride) 1049747-87-6 ≥98% 2010-06-29 4.652028413575 sb-242084-hydrochloride 181632-25-7 serotonins 5-hydroxytryptamines 5-HT neurotransmitters neuroscience receptors gut central nervous system antagonists 5-HT2C dopamine adrenergic receptors brain anxiolytic neurochemistry CNS Antigens HLA-SB Antigens HLA-PL Antigens HLA-DP HLA-SB Antigens HLA-PL Antigens HLA-DP Antigens HLA SB Antigens HLA PL Antigens HLA DP Antigens HLA-SB HLA-PL HLA-DP 4.652028413575
10010247 SB 415286 264218-23-7 ≥98% 2008-10-29 8.976077348066 sb-415286 GSK3 GSK-3 PI3K signaling PI3K signalling glycogen synthase inhibitors inhibits inhibition neuron survival glycogen synthesis Chang human liver cells line potent selective sb415286 8.976077348066
13031 SB 431542 301836-41-9 ≥98% 2009-08-10 84.917826887661 sb-431542 inhibitors inhibits inhibitions TGF-β1 TGFβ1 receptors ALK5 ALK4 ALK7 ALKs BMP ALK2 ALK3 ALK6 kinases Smad fibrosis cancers renewal embryonic stems cells induced pluripotent differentiation SB431542 84.917826887661
10443 SB 939 New 929016-96-6 ≥98% 2012-02-06 103.307489257213 sb-939 3-[2-butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl]-N-hydroxy-(2E)-2-propenamide; Pracinostat inhibits inhibitions inhibitor HDACs pan-HDAC panHDAC SB939 SB-939 histones deacetylase proliferation voronistat cancers tumors SAHA 103.307489257213
10011561 SC-51089 146033-02-5 ≥95% 2010-02-02 7.626353591159 sc-51089 CID132748 prostaglandins E2 PGE2 receptors EP1 pain antagonists analgesia glioma cells cancers tumors growth neuroprotection neurons oxidative stress SC51089 SC 51089 PGs Oxazepines 7.626353591159
10010267 SC-514 354812-17-2 ≥98% 2009-08-07 37.142839779005 sc-514 SC514 SC 514 inhibitors inhibits inhibitions IκB kinase IkB IKK2 NF-κB NFκB IL-1β IL1β genes expressions IL-6 IL6 IL-8 IL8 COX-2 COX2 iNOS LPS smooth muscles cells TLR2 TNF astrocytes 37.142839779005
70340 SC-560 188817-13-2 >98% 62.055383670963 sc-560 SC560 cyclooxygenases prostaglandins synthases COX-1 pghs-1 inhibits inhibitors selective 62.055383670963
70655 SC-58125 162054-19-5 >98% 15.691049723756 sc-58125 selective inhibitors inhibits COX-2 cox2 pghs2 pghs-2 prostaglandin synthases synthase-2 sc58125 cyclooxygenases diaryl heterocycles time-dependent 15.691049723756
10876 SC-66 871361-88-5 ≥98% 2011-06-21 17.491287292817 sc-66 SC66 SC 66 analogs cyclohexanone curcumin cancers Akts inhibitors inhibits inhibition cancers ubiquitination cells death tumors tumorigenesis 17.491287292817
89460 Sclerotiorin 549-23-5 ≥98% 2009-03-11 32.979650092081 sclerotiorin Lipoxygenase-1 inhibitor CETP Grb2 Endothelins ETa ETb LO-1 ETs LOs Penicillium soybean inhibits inhibition antagonism antagonists 32.979650092081
10572 Scriptaid 287383-59-9 ≥98% 2010-09-27 76.580690607735 scriptaid GCK 1026 histones deacetylases HDACs inhibitors inhibition inhibits cancers cloning cells arrest somatic nuclear transfers Scriptides trichostatin A mouse inbred strains somaic GCK-1026 GDK1026 hydroxylamines 76.580690607735
10004207 (S)-Flurbiprofen 51543-39-6 ≥99% 2004-06-11 4.902762430938 -s-flurbiprofen cyclooxygenases inhibitors NSAIDs COX-1 COX-2 nonsteroidal anti-inflammatory drugs cox1 cox2 pghs1 pghs2 pghs-1 pghs-2 prostaglandin H synthases synthase-1 synthase-2 inhibits inhibition (S)Flurbiprofen 4.902762430938
13332 (S)-Glycyl-H-1152 (hydrochloride) Exclusive 913844-45-8 ≥98% ✓ 2010-01-27 51.846950276243 -s-glycyl-h-1152-hydrochloride Rho Kinase Inhibitor IV Rho kinases ROCK-I p160ROCK ROCK-II G protein Rho cytoskeletons adhesions proliferation smooth muscles contraction stem cells inhibitors inhibition inhibited Fasudil hydrochloride ROCK IV h1152 h-1152 h 1152 51.846950276243
10007653 (S)-H-1152 (hydrochloride) 451462-58-1 ≥95% 2010-02-25 10.435580110497 -s-h-1152-hydrochloride Rho kinase ROCK cytoskeletal cytoskeleton smooth muscles contractions vasoconstriction neurons neurite inhibitors Y-27632 HA-1077 PKA PKC MLCK H1152 H 1152 inhibition inhibits 451462-58-1 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine H-7 H 7 h1152 h-1152 h 1152 10.435580110497
13277 (S)-HDAC-42 935881-37-1 ≥95% 2009-12-03 43.209490484960 -s-hdac-42 AR42 histones deacetylases HDACs cancers inhibitors prostate p21 Akt Bcl-XL tumors inhibition inhibits OSU-HDAC-42 43.209490484960
10010344 Simvastatin 79902-63-9 >98% 2008-02-27 21.422501973164 simvastatin MK 733 HMG-CoA reductase HMGCoA inhibits inhibitors inhibition LDL-c HDL-c statins cholesterol heart diseases CVD atherosclerosis zocor zetia exetimibe vytorin inegy TNF-.alpha. NF-.kappa.B apoptosis cancers cardiovascular NFkB atherosclerosis 21.422501973164
13617 (S)-Lisofylline Exclusive 100324-80-9 ≥98% ✓ 2010-05-27 1.493646408840 -s-lisofylline (S)-LSF; (+)-Lisofylline pentoxifyllines phosphatidic acid shock sepsis anti-inflammatory IFN-γ IL-12 β-cell insulin diabetes antiinflammatory inflammatory inflammation inflammed 1.493646408840
10012628 (S)-MG132 133407-82-6 ≥98% 2009-02-18 192.178839779005 -s-mg132 Z-Leu-Leu-Leu-CHO ubiquitin proteasome inhibitors inhibits inhibition proteolytic degradation inflammation cell cycle regulation cancers NF-kB NFkB apoptosis NF-κB mg 132 mg-132 2-LLL-CHO 192.178839779005
70290 (S)-Naproxen 22204-53-1 >99% 24.718737262123 -s-naproxen cyclooxygenases inhibitors NSAIDs COX-1 COX-2 nonsteroidal anti-inflammatory drugs cox1 cox2 pghs1 pghs2 pghs-1 pghs-2 prostaglandin H synthases synthase-1 synthase-2 inhibits 24.718737262123
13121 Sodium Butyrate 156-54-7 ≥95% 2009-07-31 79.349723756906 sodium-butyrate Butyric Acid (sodium salt) fatty acids short chains inhibitors inhibits inhibition histones deacetylases HDACs epigenetics growth arrest differentiation apoptosis cancers inflammation genes expressions pro-inflammatory proinflammatory cytokines IFN-γ IL-6 IFNγ IL6 IL-1β IL1β IFNg 79.349723756906
10010466 SP 600125 129-56-6 ≥98% 2009-01-07 11.958232044199 sp-600125 1PMV; Pyrazolanthrone; NSC 75890 c-Jun cJun JNKs inhibitors inhibits inhibition reversible cell-permeable cells COX-2 COX2 MAP kinase MAPK genes expressions apoptosis autophagy differentiation IL-10 IL10 TNF-α TNFα IFN-γ IFNγ T-cells Tcells HeLa sp600125 11.958232044199
10004883 sPLA2 (Type V) Inhibitor Screening Assay Kit - 2004-05-07 49.918184688240 spla2-type-v-inhibitor-screening-assay-kit Secretory Phospholipase A2 (Type V) assays measures kits inhibition inhibitors phospholipases inflammation eicosanoids colorimetric sPLA2s enzymes diheptanoyl thio-pc 49.918184688240
13168 Splitomicin 5690-03-9 ≥98% 2010-07-15 17.744591554854 splitomicin 1-Naphthalenepropanoic Acid sirtuins Sir2p Sir-2p Sir 2p SIR2 NAD NAD+-dependent NAD-dependent dependent histone deacetylase activity activities genes regulations lifespan life-span life span yeast expression DNA replication inhibitor inhibits inhibition Hst1 Hst-1 Hst 1 HDACs chromatin research epigenetics regulation modification Sirs small molecules Pyrones 17.744591554854
10922 SR 1001 - ≥98% 2011-06-28 82.680272954083 sr-1001 inflammation autoimmune diseases RORα RORγ retinoic-acid-receptor-related orphans receptors IL-17 TH17 cells ligands mutiple sclerosis MS agonists differentiation PBMCs inhibits inhibitors inhibition splenocytes NCoR SR1001 SR-1001 82.680272954083
9000491 SR 144528 192703-06-3 ≥98% 2009-08-05 71.692483118478 sr-144528 antagonist CB1 CB2 cannabinoids receptors inverse agonist inflammation leukocytes CP 55940 CP55940 55,940 CP55,940 pain initiation suppression immune activation sr144528 CBs synthetic 71.692483118478
10009022 (S)-SLV 319 Exclusive 464213-10-3 >98% ✓ 2007-08-16 0.216408839779 -s-slv-319 CB1 CB2 receptors cannabinoids antagonists inflammation obesity neurochemistry inflammatory neuro-inflammatory neuroinflammatory (S)-SLV319 disorders ligands 0.216408839779
13337 ST638 107761-24-0 ≥98% 2010-09-21 23.356503551697 st638 tyrosine kinases inhibitors inhibits inhibition cell signaling signalling receptors tumor necrosis factor phosphorylation TNF-α phorbol myristate acetate PMA cardiac fibroblasts TNFα TNF α TNFalpha TNF.alpha. 23.356503551697
81590 Staurosporine 62996-74-1 >98% 40.901297319419 staurosporine Stsp inhibitor inhibits protein kinase pkc-alpha pkc-.alpha. eNOS endothelial nitric oxide synthases 40.901297319419
9000631 Stearoyl Serotonin Exclusive 67964-87-8 ≥98% ✓ 2010-05-18 5.296211523283 stearoyl-serotonin N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA Hydrolase Desaturase Stearoyl-CoA Stearoyl-CoA Desaturase Stearoyl CoA Desaturase Desaturase Stearyl-CoA Stearyl-CoA Desaturase Stearyl CoA Desaturase Desaturase Stearate Stearate Desaturase Desaturase delta-9 delta-9 Desaturase 5.296211523283
13084 STF-62247 315702-99-9 ≥98% 2009-10-07 36.305745856353 stf-62247 autophagy lethality renal cells carcinoma cancers von Hippel-Lindau VHL tumors supressors genes growth rates kidneys metastasize syndrome diseases 36.305745856353
13338 SU 6656 330161-87-0 ≥95% 2009-08-04 27.395160220994 su-6656 inhibitors Src kinases Src Yes Lyn Fyn cells growth development nervous system fibrosis cancers inhibits inhibition CNS SU6656 27.395160220994
10574 Suberohydroxamic Acid 38937-66-5 ≥98% 2010-09-28 48.574947820749 suberohydroxamic-acid Suberic bis-Hydroxamic Acid; SBHA histones deacetylases HDACs inhibitors genes expression regulation epigenetics nucleosomes HDAC1 HDAC3 differentiation cells cycle arrest apoptosis cancers suberodihydroxamic acid suberoyl bishydroxamic acid inhibited inhibition Warner-Lambert Brand of Mefenamic Acid Warner Lambert Brand of Mefenamic Acid Pharmascience Brand of Mefenamic Acid First Horizon Brand of Mefenamic Acid Parke Davis Brand of Mefenamic Acid Farmasierra Brand of Mefenamic Acid Ashbourne Brand of Mefenamic Acid Pinewood Brand of Mefenamic Acid Nu-Pharm Brand of Mefenamic Acid Nu Pharm Brand of Mefenamic Acid Chemidex Brand of Mefenamic Acid Gödecke Brand of Mefenamic Acid Clonmel Brand of Mefenamic Acid Antigen Brand of Mefenamic Acid Pfizer Brand of Mefenamic Acid Apotex Brand of Mefenamic Acid Rowa Brand of Mefenamic Acid Elan Brand of Mefenamic Acid APS Brand of Mefenamic Acid PMS-Mefenamic Acid PMS Mefenamic Acid Acid Mefenaminic Mefenaminic Acid Acid Mefenamic Mefenamic Acid Forte Ponstan Ponstan Forte Apo-Mefenamic Apo Mefenamic Nu-Mefenamic Nu Mefenamic ApoMefenamic NuMefenamic Pinalgesic Contraflam Ponalgic Parkemed Ponstel Ponstan Ponalar Mefacit Pontal Ponsyl Ponmel Dysman Coslan Mefic Mefac 48.574947820749
10004386 Sulindac 38194-50-2 >98% 2004-04-20 17.175380260555 sulindac NSAIDS anti-inflammatory inhibitors inhibits cancer COX non-steroidal nonsteroidal drugs cyclooxygenases indomethacin pghs2 cox2 pghs-2 prostaglandin synthases synthase-2 17.175380260555
16860 Swainsonine 72741-87-8 ≥98% 2009-06-12 211.568867403315 swainsonine Tridolgosir Alkaloid N-linked glycoside hydrolases asparagine-linked glycoproteins glycoproteins inhibitor lysosomal α-mannosidase glycosidases Golgi α-mannosidase II N-linked glycosylation antiproliferative proliferation growth antimetastatic metastasis cancer α-mannosidase lysosomes oligosaccharides glycoproteins lysosomal storage disease toxicity locoism 211.568867403315
13085 Tenovin-1 Exclusive 380315-80-0 ≥98% ✓ 2008-09-18 28.501252302025 tenovin-1 histones sirtuins cancers p53 cell growth tumors SIRT1 SIRT2 inhibitors inhibits inhibition melonoma lymphoma 28.501252302025
13086 Tenovin-6 1011557-82-6 ≥95% 2009-02-12 62.548839779006 tenovin-6 histones sirtuins cancers p53 cell growth tumors SIRT1 SIRT2 inhibitors inhibits inhibition SIRTs transcription factors TFs 62.548839779006
10011619 Terbinafine (hydrochloride) 78628-80-5 ≥98% 2010-02-16 4.016298342541 terbinafine-hydrochloride antifungals squalene epoxidase antitumor tumors antiangiogenic anticancer cancers inhibitors inhibits inhibition Naphthalenes 4.016298342541
70302 tetramethyl Nordihydroguaiaretic Acid Exclusive 24150-24-1 ≥98% ✓ 2008-09-24 5.184364640883 tetramethyl-nordihydroguaiaretic-acid tetramethyl NDGA; TMNDGA; Tetrameprocol; M4N; EM-1421 tumors inhibitor inhibits inhibition cancers NDGAs survivin apoptosis Cdc2 HIV growing growth glioma brains antitumor organic melonomas 5.184364640883
10398 TG003 New 300801-52-9 ≥95% 2011-08-17 1.936966912906 tg003 inhibitors CDC kinasesTG 003 TG-003 TG3 TG-3 TG 3 Cdc2-like kinases Clks serine/arginine-rich proteins splicing RNA Clk1/Sty Clk4 serine rich pre-mRNA Xenopus arginine SR mRNA Sty Clk1 CLk2 Clk3 Clk4 benzothiazole inhibition inhibits inhibitor SF2 SF2/ASF ASF 1.936966912906
10522 Thapsigargin New 67526-95-8 ≥97% 2011-09-23 105.820852192546 thapsigargin calcium, ATPases, sarco/endoplasmic calcium ATPases SERCAs cells signaling activation histamine cancers tumorigenesis inflammation reticula sarcoplasmic endoplasmic 105.820852192546
13237 Thiamet G Exclusive 1009816-48-1 ≥97% ✓ 2009-06-25 34.702679558011 thiamet-g inhibitors inhibits inhibitions tau alzheimers disease O-GlcNAc OGlcNAc O-GlcNAcase OGlcNAcase O-GlcNAcylation OGlcNAcylation Thiamet-G 34.702679558011
62750 Thioetheramide-PC 116457-99-9 >95% 24.950244014733 thioetheramide-pc 1-Palmitylthio-2-palmitoylamido-1,2-dideoxy-sn-glycero-3-phosphorylcholine inhibitors thioetheramides inhibits phospholipases phosphorylcholines phosphatidyl cholines inhibitors sPLA2s activity activators 24.950244014733
10009813 thio-Miltefosine - >98% 2007-08-13 10.919558011049 thio-miltefosine analogs inhibitors inhibit inhibition CTP phosphocholine cytidylyl transerases antimetastatic antiproliferatives ceramides apoptosis antiprotazoal thiomiltefosine sulfurs thios 10.919558011049
13693 Tizoxanide New 173903-47-4 ≥98% 2011-09-13 1.258278145695 tizoxanide nitazoxanide alinia anti-viral metabolites anti-parasitic giardia lamblia crytosporidium bacteria parasites viruses diseases influenza A hepatitis B C diarrhea 1.258278145695
13074 Tosyllysine Chloromethyl Ketone (hydrochloride) 4238-41-9 ≥98% 2009-02-26 55.789392265193 tosyllysine-chloromethyl-ketone-hydrochloride TLCK (hydrochloride); 1-Chloro-3-Toxylamide-7-Amino-L-2-Heptanone (hydrochloride) TLCKs proteinase inhibitors inhibits inhibition trypsin serine histones protease proteins purifications 4272-74-6 55.789392265193
11120 TPPU Exclusive New 1222780-33-7 ≥98% ✓ 2011-10-26 6.444971864129 tppu soluble epoxide hydrolase sEH inflammation hypertension cardiovascular disease neuroscience inhibitors inhibits inhibition pharmacokinetics 6.444971864129
13044 Tranilast 53902-12-8 ≥98% 2008-08-29 83.935779005525 tranilast SB 252218; Rizaben; MK 341; Tranpro; N-(3',4'-Dimethyoxycinnamoyl)Anthranilic Acid anti-inflammatory antiinflammatory angiogenesis PGDF TGF-.beta.1 TGF.beta.1 IL-8 IL8 PGE2 TXB2 antiallergenic anti-allergenic atherosclerosis vascular disease VEGF 83.935779005525
9000784 (−)-trans-C75 Exclusive 1234694-22-4 ≥98% ✓ 2011-07-20 11.679447513812 -trans-c75 (2S,3R)-C75 trans C75 transC75 inhibitors inhibits inhibition fatty acids synthases FAS apoptosis cancers obesity C-75 apoptosis 11.679447513812
9000783 (+)-trans-C75 Exclusive 1234694-20-2 ≥98% ✓ 2011-07-20 11.679447513812 -trans-c75 (2R,3S)-C75 transC75 trans C75 fatty acids synthases FAS apoptosis cancers obesity inhibitors inhibits inhibition C-75 11.679447513812
70675 trans-Resveratrol 501-36-0 >98% 96.100285851549 trans-resveratrol (E)-Resveratrol selective cyclooxygenases inhibitors COX-1 PGHS-1 COX1 PGHS1 prostaglandins H synthases 1 antioxidants oxidative injury stress atherosclerosis sirtuins 3,5,4'-trihydroxystilbene 3,5,4'-trihydroxy-trans-stilbene 3,5,4'-THS 3,5,4'-trimethoxy stilbene 3,5,4'-trimethoxystilbene (E)-stilbenes AHR antagonists aryl hydrocarbon receptors 96.100285851549
13130 trans-Resveratrol-d4 - ≥99% deuterated product 2009-01-14 18.699378453038 trans-resveratrol-d4 (E)-Resveratrol-d4 selective cyclooxygenases inhibitors COX-1 PGHS-1 COX1 PGHS1 prostaglandins H synthases 1 antioxidants oxidative injury stress atherosclerosis deuterated LC/MS GC-MS LC-MS mass spectrometry deuterium sirtuins AHR antagonists aryl hydrocarbon receptors 18.699378453038
10010237 Triciribine 35943-35-2 >98% 2007-09-11 7.209392265193 triciribine Tricyclic Nucleoside; NSC 154020; API 2 Akt cancers inhibitors inhibition inhibits Akt-1 Akt1 Akt-2 Akt2 Akt-3 Akt3 PI3-kinase PI3kinase PI3K PI-3-kinase phosphorylation activation signalling pathway signaling 7.209392265193
10009083 Trimidox Exclusive 95933-74-7 >98% ✓ 2008-02-13 5.938674033149 trimidox VF 233 apoptosis ribonucleotide reductases cells cycles cancers dNTP HIV caspase DNA synthesis chemotherapy dGTP HL-60 5.938674033149
10011124 Trimidox (hydrochloride) Exclusive - >98% ✓ 2008-06-10 5.938674033149 trimidox-hydrochloride CF 233 (hydrochloride) apoptosis ribonucleotides reductases cells cycles cancers dNTP HIV caspases DNA synthesis chemotherapy dGTP HL-60 HCls 5.938674033149
10559 Tubastatin A (trifluoroacetate salt) Exclusive - ≥95% ✓ 2011-02-08 60.463449585635 tubastatin-a-trifluoroacetate-salt HDAC6 inhibitors histones deacetylases neuroprotection neurons epigenetics TFA inhibition inhibited neuronal protection α-tubulin alpha tubulin .alpha.tubulin a-tubulin tubastatin-A Acids Hydroxamic Hydroxamic Acids Acid Hydroxamic Hydroxamic Acid 60.463449585635
10011251 TWS119 601514-19-6 ≥90% 2008-12-11 16.008416206261 tws119 inhibitors inhibits inhibition stem cells differentiation neurogenesis neuron kinases GSK-3β GSK3β TWS 119 TWS-119 16.008416206261
70970 U-0126 109511-58-2 >98% 2007-11-20 22.636290449881 u-0126 U0126 MAPK MAP Kinases inhibitors inhibits inhibition MEK MEK1 MEK2 signal transduction ATP adenosine triphosphate U 0126 22.636290449881
10009085 U-18666A 3039-71-2 >95% 2007-01-19 30.859149171270 u-18666a Niemann-Pick type C NPC apoptosis neuronal death Alzheimers AD neurodegeneratives diseases trafficking unesterified ER cells membranes cateracts epilepsy Free cholesterol loading NSC 70801 Endoplasmic reticulum atherosclerosis inhibits inhibitors inhibition endosomes lysomes oxidosqualene cyclases atherosclerosis 30.859149171270
70740 U-73122 112648-68-7 >99% 57.424861878454 u-73122 inhibitors inhibits PLC phospholipases C HIV-1 integrase u73122 57.424861878454
10045 UCM707 390824-20-1 >98% 2004-01-30 22.976160220994 ucm707 cannabinoids neurotransmitter inhibitors AEA lipids CB1 UR1 receptors anandamide hydrolysis fatty acids neurochemistry neuroscience 22.976160220994
13631 UNC0224 Exclusive 1197196-48-7 ≥98% ✓ 2010-08-10 27.081454309544 unc0224 inhibitors inhibits inhibition histones methyltransferases genes regulation regulator chromatin remodeling UNC 0224 UNC-0224 G9a SET8 SET7/9 lysine HMTase 27.081454309544
10582 UNC0321 (trifluoroacetate salt) Exclusive - ≥95% ✓ 2011-03-15 14.321668214034 unc0321-trifluoroacetate-salt methyltransferases inhibitors histones genes regulation chromatin remodeling G9a HMTase inhibited inhibition potent selective MT SET7/9 SET8 PRMT3 JMJD2E 14.321668214034
10734 UNC0638 Exclusive 1255580-76-7 ≥98% ✓ 2011-05-03 12.545322873385 unc0638 methyltransferases inhibitors histones genes regulation chromatin remodeling inhibited inhibition G9a MT GLP PRMT 3 SUV39H2 SET7/9 SET8 inhibits H3K9 dimethylation MDA-MB231 12.545322873385
10046 URB597 546141-08-6 >98% 54.148442993470 urb597 FAAH fatty acid amide hydrolases inhibitors URB-597 anandamides lipids inhibition selective selectivity AEA inhibits hydrolysis hydrolyze arachidonoyl cannabinoids ethanolamides neuroscience neurochemistry 54.148442993470
10674 URB937 Exclusive - ≥98% ✓ 2011-03-08 17.586224677716 urb937 FAAH anandamide AEA inhibitors peripheral pain Cannabinoids 17.586224677716
70670 Valeroyl Salicylate 64206-54-8 >99% 0.632504604051 valeroyl-salicylate 2-Valeryloxybenzoic Acid selective cyclooxygenase inhibitors COX-1PGHS-1 prostaglandin H synthase 1 prostaglandins 0.632504604051
13033 Valproic Acid (sodium salt) 1069-66-5 ≥95% 2009-10-21 27.022965009207 valproic-acid-sodium-salt Sodium Valproate; 2-Propylvaleric Acid valeric acids anticonvulsant seizures inhibitors histones deacetylases HDAC glycogen synthase kinases GSK3 inositol-1,4,5-trisphosphate IP3 combination therapy cancers Alzheimer's diseases stem differentiation self-renewal 27.022965009207
13131 VER-49009 Exclusive 940289-57-6 ≥98% ✓ 2010-07-09 3.563255985266 ver-49009 heat shock proteins Hsp90 inhibitors Hsp27 Hsp72 cells cycle arrest apoptosis inhibits inhibition isoxazole survivin C-RAF B-RAF PRMT5 molecular chaperones folding signalling signaling VER49009 VER 49009 cancers pyrazoles 3.563255985266
13132 VER-50589 Exclusive 747413-08-7 ≥98% ✓ 2010-04-06 2.552573664825 ver-50589 heat shock proteins Hsps Hsp90 cancers inhibitors inhibits inhibition Hsp27 Hsp72 C-RAF B-RAF survivin PRMT5 cells cylce arrest apoptosis tumors growth glioblastoma molecular chaperones protein folding signaling signalling pharma Isoxazoles 2.552573664825
9000976 Vigabatrin 68506-86-5 ≥95% 2011-05-04 16.287348066298 vigabatrin γ-Vinyl GABA; Sabril™ 60643-86-9 neurotransmitters γ-aminobutyric acids GABA inhibitors seizures epilepsy neuroscience gamma-vinyl-gamma-aminobutyric gamma vinyl aminobutyric gamma-vinyl-GABA Sabrilex Sabril 16.287348066298
80330 Vinyl-L-NIO (hydrochloride) 728944-69-2 >98% 2008-08-11 16.151473296500 vinyl-l-nio-hydrochloride nitric oxide synthase NOS nNOS selective inhibitors inhibits inhibition ornithine 16.151473296500
13531 (−)-Warfarin 5543-57-7 ≥98% 2009-10-01 19.882348066298 -warfarin (S)-Warfarin anticoagulants hearts attacks strokes clotting blood cardiovascular diseases vitamins K rodenticides warfarins anti-cogulants 19.882348066298
13526 (+)-Warfarin 5543-58-8 ≥98% 2009-10-01 10.528464088397 -warfarin (R)-Warfarin anticoagulants hearts attacks strokes clotting blood cardiovascular diseases vitamins K rodenticides warfarins anti-cogulants 10.528464088397
13566 (±)-Warfarin 81-81-2 ≥98% 2009-09-29 6.460441988950 -warfarin Coumadin; Zoocoumarin; Coumafene; Athrombine K; WARF 42 anticoagulants heart attacks strokes clotting blood cardiovascular diseases vitamin K rodenticide anti-coagulants racemic mixture liver accumulation accumulates clots 6.460441988950
10010591 Wortmannin 19545-26-7 ≥98% 2008-11-21 43.700611040279 wortmannin KY 12420 phosphoinositide 3-kinase PI3K cells growth differentiations cancers motility inhibitors inhibits inhibition irreversible polo-like kinases PLK1 PLK3 mTOR DNA-PK DNAPK PL4K MLCK p38 MAPK 43.700611040279
13671 Wortmannin-Rapamycin Conjugate - ≥98% 2010-05-11 25.089822999795 wortmannin-rapamycin-conjugate phosphoinositides 3-kinases PI3K mammalian targets mTOR cancers inhibitors inhibits inhibition complex 1 mTORC1 tumors bevacizumab VEGF colons A498 HT29 53123-88-9 sirolimus prodrug linkers links 19545-26-7 KY 12420 renal phosphatidyl inositols 25.089822999795
10011213 WWL70 Exclusive 947669-91-2 >97% ✓ 2008-04-15 9.642836095764 wwl70 serine hydrolase ABHD6 inhibitors inhibits inhibition 2-AG endocannabinoids .alpha./.beta. a/b alpha/beta neurochemistry cannabinoids inhibitors 9.642836095764
13604 WYE-354 New 1062169-56-5 ≥98% 2012-01-12 80.628722529159 wye-354 mTOR mTORC1 mTORC2 inhibitors inhibits inhibition PI3K cancers cells growth PTENs tumors rapamycin complex 1 2 G1 phosphatidylinositol 3-kinase α PI3Kα kinases 80.628722529159
13639 WZ811 55778-02-4 ≥95% 2010-03-22 14.248908839779 wz811 CXC chemokines receptors CXCR4 stromal cell-derived factor-1 SDF-1 CXCL12 hematopoietic stem cells chemotaxis lymphocytes growth metastasis cancers T cells HIV infection inhibitors antagonist cAMP Matrigel invasion breast cancer adenocarcinoma inhibition alpha-Aminotoluene alpha Aminotoluene Phenylmethylamine Benzylamines 14.248908839779
13596 XAV939 284028-89-3 ≥98% 2009-12-03 13.680441988950 xav939 Wnt cancers β-catenin APC axin GSK3 poly-ADP-ribosylation tankyrases TNKS1 TNKS2 inhibitors inhibition inhibits 13.680441988950
10005583 Y-27632 (hydrochloride) 129830-38-2 >98% 2007-11-29 182.138674033149 y-27632-hydrochloride Y27632 inhibitors inhibit inhibition Rho ROCK ROCK-II ROCKII PRK2 smooth muscle contraction cell adhesion signal transduction kinase phosphorylation HCl competative Y 27632 146986-50-7 182.138674033149
11168 (−)-YK-4-279 New - ≥98% 2011-12-19 62.516298342541 -yk-4-279 ES-FLI1 oncogenes Ewing's sarcomas RNA helicases tumors cancers inhibitors apoptosis ETS transcription factors ERG ETV1 prostate fusion proteins diseases YK4279 YK 4279 growth xenografts cells chemotherapy resistant Ewings ESFLI1 ES FLI1 prostate 62.516298342541
11167 (+)-YK-4-279 New 1261038-93-0 ≥98% 2011-12-16 60.849631675875 -yk-4-279 ES-FLI1 oncogenes Ewing's sarcomas RNA helicases tumors cancers inhibitors apoptosis ETS transcription factors ERG ETV1 prostate YK4279 YK 4279 fusion proteins diseases growth orthotopic xenografts cells chemotherapy resistant Ewings EWS-FLI1 reduces in vitro in vivo family prostate cancers enantiomers EWSFLI1 EWS FLI1 60.849631675875
13661 YK-4-279 1037184-44-3 ≥98% 2010-02-05 44.477041129527 yk-4-279 ES-FLI1 oncogene Ewing's sarcomas RNA helicases A RHAs tumors cancers inhibitors apoptosis inhibition inhibited Ewings YK 4-279 YK4279 YK 4279 YK 4 279 Pentaacetic Acid, Diethylenetriamine Acid, Diethylenetriamine Pentaacetic Diethylenetriamine Pentaacetic Acid calcium trisodium pentetate Pentetic Acid DTPA pentacin penthanil 44.477041129527
13576 YM-201636 371942-69-7 ≥95% 2010-04-14 6.107066298342 ym-201636 PIKfyve phosphoinositide kinase PIK zinc finger domains phosphatidylinositol 3-phosphate PI3P PI(3,5)P2 membrane trafficking cytoskeleton inhibitors endosomal trafficking endosomes phagocytosis retrovirus virology adipocytes insulin glucose diabetes YM201636 YM 201636 Aminopyridines 6.107066298342
18113 YM-53601 Exclusive 182959-33-7 ≥98% ✓ 2009-08-11 5.105911602209 ym-53601 squalene synthases inhibitors cholesterol triglycerides HMG-CoA reductase fibrates hyperlipidemia hypercholesterolemia lipid-lowering activities inhibitor inhibited 5.105911602209
13246 YM-58483 223499-30-7 ≥98% 2009-11-16 1.983563535911 ym-58483 BTP 2 calcium channels leukocytes leukotrienes eicosanoids inflammation asthma allergy IL-2 IL-4 lymphocytes eosinophils NF-AT CRACs CysLTs interleukin-4 BTP2 BTP-2 CysLT 1.983563535911
13665 YS121 Exclusive 916482-17-2 ≥98% ✓ 2010-04-02 20.004903314917 ys121 Microsomal Prostaglandin E2 Synthase-1 mPGES-1 cyclooxygenase-2 COX-2 PGE2 inflammation fever pain 5-Lipoxygenase 5-LO leukotrienes LTs inhibitors LTB4 cyclooxygenase-1 COX-1 LTC4 LTD4 LTE4 inhibition Pyrimidines inhibits PGs YS 121 YS-121 20.004903314917
10010421 Zaprinast 37762-06-4 ≥98% 2008-09-18 5.545101289134 zaprinast 2-(o-Propoxyphenyl)-8-azapurin-6-one; M&B 22,948 sildenafil viagra phophodiesterase cGMP PDE5 GRP35 inhibitors inhibits inhibition M&B 22948 55122-20-8 5.545101289134
10975 Zebularine New 3690-10-6 ≥98% 2011-08-23 14.907058546404 zebularine DNMTs inhibitors DNA methyltransferases cancers cells analogs cytidines methylation carcinomaTK6 jurkat KG-1 HCT116 14.907058546404
13271 ZLJ-6 Exclusive 1051931-39-5 ≥98% ✓ 2009-06-17 38.591892265193 zlj-6 inhibitors cyclooxygenase COX-1 COX-2 5-lipoxygenase 5-LO inflammation pain ZLJ6 ZLJ 6 38.591892265193
13601 ZM 447439 331771-20-1 2010-08-03 3.186491712707 zm-447439 auroras A B C kinases mitosis cytokinesis centromere inhibitors inhibits inhibition cancers Benzamides 3.186491712707
9001083 α-Pyrrolidinopentiphenone (hydrochloride) Exclusive New 5485-65-4 ≥98% ✓ 2011-10-11 60.351186131782 -pyrrolidinopentiphenone-hydrochloride α-PVP; 2-(1-pyrrolidinyl)-Valerophenone; O-2387 14530-33-7 designer drugs forensics pyrovalerone bath salts inhibits inhibitors inhibition transporters neurotransmitters dopamine norepinephrine uptake monoamine analogs alpha PVP APVP hydrochloride HCl psychoactive stimulant 60.351186131782
10010947 β-cyano-L-Alanine 6232-19-5 ≥98% 2008-11-11 19.837716390423 -cyano-l-alanine BCA H2S gasotransmitter inhibitors inhibits inhibition CSE vasodilation inflammation sulfides 19.837716390423
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