See personalized New Product recommendations! Get personalized New Product recommendations! Register or Login for personalized New Product recommendations!

Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…
Please feel free to continue placing orders via our website or via fax at 734-971-3640. You may send an email to customer service at custserv@caymanchem.com , or to technical support at techserv@caymanchem.com which we will respond to the next business day. Cayman will resume regular business hours and shipping schedules on Tuesday, May 29, 2012. Thank you for your patience and understanding.

Chemical Class · Receptor Antagonist

· See all 100+ product categories

Item Number Product Sizes & Pricing CAS Purity Image Exclusive Introduction Date Mojo Plain Text Name Synonyms Keywords Interest
20150 14,15-dehydro Leukotriene B4 114616-11-4 >97% 2008-06-02 41.183911602210 14-15-dehydro-leukotriene-b4 14,15-dehydro LTB4 leukotrienes inflammation leukocytes antagonist LTB4 5-LO 5LO allergy asthma LTs inhibits inhibitors inhibition 41.183911602210
10008510 15(R)-Pinane Thromboxane A2 - >98% 2006-06-14 7.662983425415 15-r-pinane-thromboxane-a2 15(R)-PTA2 TXA2 anatagonists TP receptors synthases platelets aggregation analogs inhibits inhibitors inhibition U-46619 cat coronary artery constriction 15-epimer 7.662983425415
10010129 AG-041R Exclusive 199800-49-2 ≥98% ✓ 2008-12-16 58.820828729281 ag-041r CCKs gastrin receptors antagonist cancers proliferations apoptosis NS-398 NS398 NS 398 58.820828729281
13203 Agomelatine 138112-76-2 ≥98% 2009-11-06 1.596353591160 agomelatine Valdoxan® melatonin circadian rhythm MT1 MT2 serotonin 5-HT noradrenaline dopamine antidepressant anti-depressant S20098 S-20098 S 20098 1.596353591160
19023 AH 23848 (calcium salt, hydrate) - ≥90% 2009-02-26 76.191248618784 ah-23848-calcium-salt-hydrate AH23848B AH 23848 TXBs thromboxane PGEs PGE2 receptors prostanoids TPs EP4 antagonist blockers inhibitors inhibits inhibition TXA2 platelets smooth muscle bronchial U-46619 U46619 fibroblasts cancers metastasis 81739-45-9 AH-23848 76.191248618784
14050 AH 6809 33458-93-4 ≥98% 88.760055248619 ah-6809 EP1 EP2 receptors antagonists AH6809 DP PGE2 prostaglandins ah-6809 88.760055248619
16735 AL 8810 246246-19-5 >98% 38.367000789266 al-8810 FP antagonists prostaglandins PGFs receptors AL8810 AL-8810 PGF2alpha PGF2.alpha. analogs 38.367000789266
10113 AL 8810 isopropyl ester 208114-93-6 >98% 52.654996930632 al-8810-isopropyl-ester FP antagonists prostaglandins PGFs receptors AL8810 AL-8810 PGF2alpha PGF2.alpha. analogs esters 52.654996930632
13648 Alfuzosin (hydrochloride) 81403-68-1 ≥98% 2010-07-19 0E-12 alfuzosin-hydrochloride Uroxatral; SL 77499-10 α1-adrenergic receptors antagonists lower urinary tract symptoms benign prostatic hyperplasia BPH adrenoceptors α1A α1B α1D contractions smooth muscles antihypertensives vasodilators urinary flow 133880-44-1 Urion Alfoten SL 77-499-10 anti-hypertensives alpha 1 .alpha.1 Xatral Quinazolines 0E-12
10006974 AM630 164178-33-0 ≥98% 2009-02-09 47.443079312365 am630 Iodopravadoline neurochemistry neuroscience cannabinoids CB1 CB2 antagonist inverse agonist antinociception pain receptors 47.443079312365
10009021 AVE-1625 Exclusive 358970-97-5 ≥98% ✓ 2008-04-03 5.985497237569 ave-1625 cannabinoids CB1 receptors schizophrenia parkinsons disease alzheimers disease metabolism obesity SR-141716 lipolysis glycogenolysis antagonist endocrinology neurochemistry 5.985497237569
10532 BayCysLT2 Exclusive 712313-33-2 ≥95% ✓ 2010-09-22 2.552633517495 baycyslt2 CAY10633 HAMI3379 cysLT2 receptors cardiovascular disease antagonists leukotrienes LTC4 LTD4 cysteinyl HAMI 3379 HAMI-3379 cyslts CAY10633 CAY-10633 CAY 10633 2.552633517495
10156 BAY-u3405 116649-85-5 >98% 2004-11-17 19.377381215470 bay-u3405 Ramatroban human medications allergic rhinitis antagonists thromboxanes TP receptors DP2/CRTH2 prostaglandins PGD2 7-transmembrane GPCRs G-protein-coupled BAYu3405 19.377381215470
70770 BAY-u9773 154978-38-8 >95% 2005-03-30 42.649613259668 bay-u9773 asthma leukotrienes CysLTs allergy antagonists cysteinyls receptors 7-transmembranes pranlukasts montelukasts CysLT2 CysLT1 CysLT-1 CysLT-2 42.649613259668
11727 Bicuculline New 485-49-4 ≥98% 2012-05-18 104.148098219766 bicuculline NSC 32192 bicucullin bucuculline GABA GABAA receptors antagonists epilepsy chloride channels neurosciences retinal neurobiology receptive fields allosteric inhibits inhibitors inhibitions cortical neurons blocks brains slices 104.148098219766
10155 BM 567 284464-77-3 >98% 2005-03-31 43.370676795580 bm-567 platelets thromboxanes TXA2 atherosclerosis synthases inhibits inhibition inhibitors antagonists BM567 BM-567 thrombogenic vasocontrictors TP receptors eicosanoids strokes myocardial infarctions GPCR vascular smooth muscles protein-coupled license:liege 43.370676795580
10488 Bupropion (hydrochloride) 31677-93-7 ≥98% 2010-08-16 6.125262942501 bupropion-hydrochloride NSC 315851 34841-36-6 Zyban Wellbatrin inhibitors inhibits inhibition reuptake dopamine norepinephrine Voxra Aplenzin Amfebutamone antagonists neuronal acetylcholine nicotinic receptors nAChR antidepressant depression neurosciences Wellbutrin 1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone GlaxoSmithKline Brand 2 of Bupropion Hydrochloride GlaxoSmithKline Brand 1 of Bupropion Hydrochloride Glaxo Wellcome Brand 3 of Bupropion Hydrochloride Glaxo Wellcome Brand 2 of Bupropion Hydrochloride Glaxo Wellcome Brand 1 of Bupropion Hydrochloride Esteve Brand of Bupropion Hydrochloride Bupropion Hydrochloride Bupropion Hydrochloride Zyban (Anti-Smoking) Amfebutamone Wellbutrin Bupropion Bupropion Zyntabac Quomen Isomer 6.125262942501
12060 BW A868C 118675-50-6 >98% 82.880662983425 bw-a868c hydantoin DP receptors antagonists BW245C adenylate cyclase antiaggregatory BWA868C BW-A868C BW-245C prostaglandins PGD2 DP1 82.880662983425
10489 Candesartan cilexetil 145040-37-5 ≥98% 2011-04-08 57.833971761817 candesartan-cilexetil TCV-116 angiotensin II receptors antagonists hypertension diabetes AT1 type 1 stress diastolic blood pressure anti-hypertensive antihypertensive 57.833971761817
10007518 Capsazepine 138977-28-3 ≥98% 2006-03-29 58.537209944750 capsazepine vanilloid receptors 1 VR1 transient potential TRP endogenous stimuli tissues injury inflammation pain antagonists capsaicin Ca2+ neonatal rats dorsal root ganglias Chinese hamsters ovary ovaries cells 58.537209944750
10005186 CAY10441 Exclusive 221529-58-4 >98% ✓ 2004-09-16 95.979825046041 cay10441 RO1138452 receptors antagonists IPs prostaglandins carbaprostacyclins inhibits inhibitors inhibition analgesics high-affinity ligands neuroblastoma cyclic AMP cAMP adenylate cyclase 4,5-dihydro-1H-imidazol-2-yl-4-4-isopropoxy benzyl phenylamine atherosclerosis 95.979825046041
10005033 CAY10444 Exclusive 298186-80-8 ≥98% ✓ 2004-10-05 58.748941068140 cay10444 BML-241 receptors antagonists S1P3 EDG3 sphingosines sphingosine-1 sphingosine1 phosphates Hela cells G-proteins CAY-10444 BML241 58.748941068140
10005633 CAY10448 - ≥98% 2004-10-01 17.571325966850 cay10448 capsaicin capsicum vanilloids receptors antagonists cannabinoids analgesia anandamides analgesic vanillylamines amides analogs transient potential VR1 pain TRPV1 neurochemistry neuroscience 17.571325966850
10005913 CAY10449 Exclusive - >98% ✓ 2004-10-26 64.277476979742 cay10449 receptors antagonists IPs prostaglandins carbaprostacyclins inhibits inhibitors inhibition analgesics high-affinity ligands neuroblastoma adenylate cyclase cyclic AMP cAMP iloprost athersclerosis CAY 10449 64.277476979742
10006735 CAY10471 627865-18-3 ≥98% 2005-06-22 17.541892265193 cay10471 ramatroban DP2 CRTH2 antagonists TP receptors prostaglandins PGD2 7-transmembranes GPCRs G protein-coupled BAY-u3405 human medications allergic rhinitis analogs 17.541892265193
10007955 CAY10498 863202-33-9 ≥98% 2006-08-02 41.749779005525 cay10498 2-phenyl-amino-N6-endo-norbornyladenine adenosine receptor antagonist A1 A2A A2B A3 AR G-protein stroke inflammation glaucoma neurodegenerative disease reversine dedifferentiation neurochemistry ophthalmology 41.749779005525
10010396 CAY10535 Exclusive - >98% ✓ 2008-05-06 198.923480662983 cay10535 TPbeta TPb TP.beta. TPalpha TP.alpha. TPa TXA2 thromboxanes antagonists platelet aggregations U-46619 U46619 198.923480662983
10012553 CAY10595 Exclusive 916047-16-0 ≥97% ✓ 2009-07-08 8.011823204419 cay10595 DP2 PGD2 CRTH2 chemotaxis inflammation antagonists prostaglandins PGDs 8.011823204419
10012539 CAY10597 916046-55-4 ≥98% 2009-03-11 3.705348066298 cay10597 DP2 PGD2 CRTH2 chemotaxis inflammation antagonist 5-chloro-1'-[(2-fluorophenyl)methyl]-2,2',5'-trioxo-spiro[3H-indole-3,3'-pyrrolidine-1(2H)-acetic acid 3.705348066298
13358 CAY10608 Exclusive 457897-92-6 ≥98% ✓ 2010-04-29 1.305248618784 cay10608 N-Methyl-D-aspartate NMDA receptors antagonists glutamate glycine propanolamine NR2B subunit AMPA kainate neuroprotection neurochemistry antagonizes potently selectively non-competitively 1.305248618784
13615 CAY10614 Exclusive 1202208-36-3 ≥98% ✓ 2010-03-22 11.377624309392 cay10614 1115270-65-9 Lipids A endotoxins lipopolysaccharides LPS gram-negative bacterias infections toll-like receptor 4 TLR4 immune responses antagonists sepsis inflammation 11.377624309392
10820 CAY10651 Exclusive - ≥98% ✓ 2011-06-15 0E-12 cay10651 Glutamate neurotransmitters receptors mGlu5 pain anxiety antagonists gastresophageal reflux diseases dyskinesia fragile X syndromes drug addictions cortical astrocytes functional binding assays mobilization calcium CNS 0E-12
10011126 Clobenpropit (hydrobromide) 145231-35-2 ≥98% 2008-12-04 0.882665745856 clobenpropit-hydrobromide Carbamimidothioic Acid; VUF-9153 histamines receptors antagonist GABA neurons brains seizures 0.882665745856
13657 (±)-Clopidogrel (hydrochloride) 90055-48-4 ≥98% 2011-04-11 4.077348066299 -clopidogrel-hydrochloride platelets aggregation antagonists P2Y12 receptors ADPs prodrugs anti-thrombic antithrombic 4.077348066299
10011296 (E)-Guggulsterone 39025-24-6 ≥98% 2009-12-03 2.875138121547 -e-guggulsterone anti-flammatory cancers FXR bile acids LDL cholesterol antiinflammatory atherosclerosis obesity diabetes inflammation farnesoid X receptors guggul trees 2.875138121547
11578 Eprosartan (mesylate) New 144143-96-4 ≥98% 2012-05-16 90.719337016575 eprosartan-mesylate SKF 108566J cardiovascular diseases hypertension angiotensin II rennin blood pressure ARB receptors blockers antagonists AT1 mesylate nervous system nerves vessels 90.719337016575
13841 GANT 61 500579-04-4 ≥98% 2011-04-20 70.787052639656 gant-61 NSC 136476 Hedgehog transcription factors genes expression GLI cancer glioblastomas antagonists development regulation GANT61 GANT-61 pyridines pyrimidines NSC136476 NSC-136476 TFs 70.787052639656
10009162 GW 627368X Exclusive 439288-66-1 ≥96% ✓ 2007-05-14 32.455359116022 gw-627368x EP4 receptor antagonist TP prostanoid prostaglandin platelets U-46619 aggregation PGE2 EP1 EP2 EP3 GW627368X GW-627368X 32.455359116022
10010410 GW 848687X 612831-24-0 ≥98% 2009-11-25 16.795624309392 gw-848687x Receptors EP1 PGE2 vasoconstriction bronchoconstriction hyperalgesia allodynia gastric protection relief hyperthermia sleep antagonists thromboxanes TP inflammation arthritis pain inflammatory GW848687X GW-848687X 16.795624309392
70785 GW 9662 22978-25-2 ≥98% 71.039342541436 gw-9662 GW-9662 GW9662 ligands ppar.gamma. ppargamma peroxisome proliferator-activated nuclear endocrinology receptors antagonists atherosclerosis 71.039342541436
9000497 GW 9662-d5 Exclusive - ≥99% deuterated forms (d1-d5) ✓ 2009-09-30 33.777096378146 gw-9662-d5 deuterateds deuterium GC/MS GC-MS LC/MS LC-MS mass spectrometry GW-9662 GW9662 ligands ppar.gamma. γ ppargamma peroxisome proliferator-activated nuclear endocrinology receptors antagonists atherosclerosis TZDs thiaolidinediones PPARs 33.777096378146
10580 HAMI3379 Exclusive 712313-35-4 ≥90% ✓ 2011-03-14 89.886527229676 hami3379 cysLT2 receptors cardiovascular diseases antagonists leukotrienes LTC4 LTD4 cysteinyl LTs CysLTs perfusion pressure decrease contractility cyclohexanecarboxylic acids 89.886527229676
19021 I-SAP 133538-58-6 ≥98% 7.417679558011 i-sap Iodophenyl sulfonyl amino pinane Thromboxane A2; Iodophenyl sulfonyl amino pinane TXA2 thromboxanes ISAP pinane analogs agtagonists TP receptors atherosclerosis 7.417679558011
10012699 JMV3002 Exclusive 925239-03-8 ≥98% ✓ 2009-03-11 127.926906077347 jmv3002 ghrelins obesity growth hormones foods intake receptors antagonists secretagouge hexarelin-stimulated secretion 127.926906077347
10011925 JNJ-7777120 459168-41-3 ≥98% 2011-02-24 0.482320441989 jnj-7777120 histamines H4 receptors antagonists inflammation Piperazines 0.482320441989
10009458 JTE-013 383150-41-2 ≥98% 2007-01-18 70.191724984653 jte-013 reverses inhibition inhibits coronary artery smooth muscles lipids cells proliferation cytoskeletal morphogenesis GPCRs protein-coupled receptors antagonists S1P2 humans rats EDG5 sphingosines sphingosine-1-phosphates sphingosine1 inhibitors JTE013 FDG-5 cancers 70.191724984653
10012659 Ki16425 355025-24-0 ≥95% 2008-11-06 118.064818907305 ki16425 LPA1 LPA2 LPA3 LPA4 LPA5 lysophosphatidic acids cancers antagonist receptors selective 118.064818907305
10011565 L-161,982 147776-06-5 ≥98% 2009-02-26 47.734990791896 l-161-982 PGEs PGE2 EPs EP4 receptors antagonist bone formation inflammation cells proliferation colon cancers L161982 L-161982 47.734990791896
10011562 L-655,240 103253-15-2 ≥98% 2009-10-15 8.148004143646 l-655-240 platelet aggregation smooth muscle constriction contraction antagonist receptors TXA2 receptor TP thromboxane TPα TPβ TXA2 bronchoconstriction L-655240 L 655240 8.148004143646
20115 Leukotriene B4 dimethyl amide 83024-92-4 >97% 90.676325966851 leukotriene-b4-dimethyl-amide LTB4 dimethyl amide leukotrienes LTB4 antagonists analogs BLTR1 receptors amides 90.676325966851
20112 Leukotriene B4 Ethanolamide - >97% 33.184814522494 leukotriene-b4-ethanolamide LTB4-EA BLTR2 receptors leukotrienes LTB4 ethanolamides cannabinoids anandamides ligands BLT2 neuroscience ethanolamines 33.184814522494
13453 LH 21 611207-11-5 ≥98% 2011-03-22 20.343434622468 lh-21 cannabimimetic CBs cannabinoids CB1 receptors antagonists pain weight gain obesity LH-21 LH21 central 20.343434622468
10006594 Losartan (potassium salt) 124750-99-8 ≥98% 2005-05-10 40.982331842497 losartan-potassium-salt MK 954; DuP-753 AT1 receptors antagonists angiotensins II type 1 hormones regulates blood pressure regulating hypertension atherosclerosis renal functions vasodilation vasodilating platelets neutrophils aggregation endothelium losartans losartan potassium 40.982331842497
70710 LY171883 88107-10-2 >98% 12.531436464088 ly171883 LTD4 receptors antagonists leukotrienes ly-171883 cysLT1 12.531436464088
10010024 LY223982 Exclusive 117423-74-2 ≥98% ✓ 2008-07-24 2.106629834254 ly223982 SKF 107324; CGS 23131 LTB4 receptors inflammation antagonist benzophenone neutrophil chemotaxis leukotriene B4 fatty acids 5-LO 5LO CGS23131 SKF107234 2.106629834254
70715 LY255283 117690-79-6 >98% 2004-02-19 38.013121546961 ly255283 receptors antagonists inhibits inhibitors leukotrienes receptors BLT1 BLT2 chemotaxis LY-255283 LY 255283 38.013121546961
10009768 LY293111 Exclusive 161172-51-6 ≥98% ✓ 2009-02-09 62.413743093923 ly293111 Etalocib; VML 295 LTBs LTB4 receptors inflammation antagonist benzophenone neutrophil chemotaxis pancreatic cancers 62.413743093923
70720 MK 571 (sodium salt) - ≥95% 19.976988950276 mk-571-sodium-salt L 660711 LTD4 receptors antagonists leukotrienes mk571 mk-571 salts L660711 L-660711 cysLT1 115104-28-4 19.976988950276
10008318 Montelukast (sodium salt) 151767-02-1 ≥98% 2006-04-20 30.970520915548 montelukast-sodium-salt Singulair® cysteinyl-leukotrienes cysLT1 receptors antagonists LTC4 LTD4 mediators asthma hypersensitivity bronchoconstriction microvascular permeability vasoconstrictors coronary arteries protein-coupled GPCRs selective potent 30.970520915548
10230 (+)-Muscarine (iodide salt) 24570-49-8 ≥95% 2010-05-06 0.801602209944 -muscarine-iodide-salt neurochemistry 300-54-9 2438-77-9 poisonous mushroom acetylcholine G proteins Alzheimer's disease signal transduction L-muscarine Amanita muscaria 0.801602209944
10517 Naphyrone (hydrochloride) 850352-11-3 ≥97% 2011-08-29 105.016779230112 naphyrone-hydrochloride O-2482; NRG-1; Naphpyrovalerone; β-Naphyrone analogs MDPV forensics sciences designer drugs 850352-53-3 pyrovalerones cathinones dopamine serotonins norepinephrines bath salts 105.016779230112
10004184 NESS 0327 Exclusive 494844-07-4 >98% ✓ 2008-05-27 34.593259668508 ness-0327 neurochemistry neuroscience cannabinoids antagonist CB1 CB2 SR 141716A rimonabant WIN 55212-5 pain obesity 34.593259668508
10006456 NO-Losartan A 791122-48-0 ≥97% 2005-05-10 41.876298342541 no-losartan-a AT1 receptors antagonists NO-donors nitric oxides angiotensins II type 1 hormones regulates blood pressure regulating hypertension atherosclerosis mammalian renal functions vasodilation vasodilating inhibits platelets neutrophils aggregation endothelium anti-hypertensives losartans 41.876298342541
10010299 Oleoyl 3-carbacyclic Phosphatidic Acid Exclusive - ≥95% ✓ 2009-10-14 15.632520718232 oleoyl-3-carbacyclic-phosphatidic-acid 3-ccPA 18:1 cyclic phosphatidic acids cPAs lysophosphatidic LPA ccPA 3ccPA oleate transcellular migration MM1 cells mesothelial autotoxin cancer survival growth migration invasion metastasis antagonist LPA1 LPA2 LPA3 476310-24-4 15.632520718232
14070 ONO-8711 216158-34-8 ≥98% 2011-06-15 21.559254143646 ono-8711 ONO 8711 ONO8711 prostaglandins EPs EP1 receptors potent PGs antagonists AH-6809 AH 6809 AH6809 14060 14050 SC-19220 SC19220 SC 19220 21.559254143646
11345 Paxilline New 57186-25-1 ≥98% 2012-03-01 10.565642497180 paxilline (+)-Paxilline Paxicillin Paxillin inhibitors inhibits inhibitions channels K+ blockers potassium BKCa cells signaling smooth muscle vascular cardiovascular neuronal neuroscience 10.565642497180
19020 Pinane Thromboxane A2 71111-01-8 >98% 14.260674033149 pinane-thromboxane-a2 PTA2; Pinane TXA2 Thromboxanes analogs TXA2 antagonists TP receptors atherosclerosis 14.260674033149
10011332 Plerixafor (hydrochloride hydrate) 155148-31-5 ≥98% 2009-02-10 177.592850828729 plerixafor-hydrochloride-hydrate Mobozil™; SID 791; JM 3100; AMD 3100 stem cells hematopoiesis HIV lymphocyte replication metastasis cancers growth antagonist CXCR4 SDF-1 SDF1 CXCL12 ireversible virus inhibits inhibition inhibitor 177.592850828729
16032 Prostaglandin F2α dimethyl amide 68192-15-4 >98% 9.995876611418 prostaglandin-f2-dimethyl-amide PGF2α dimethyl amide; Dinoprost dimethyl amide PGF2alpha PGF2.alpha. amides prostaglandins FP receptors antagonists 9.995876611418
16033 Prostaglandin F2α dimethyl amine - >98% 16.756368937998 prostaglandin-f2-dimethyl-amine PGF2α dimethyl amine; Dinoprost dimethyl amine PGF2alpha PGF2.alpha. amines prostaglandins FP receptors antagonists 16.756368937998
10011032 QX-314 (bromide) 24003-58-5 ≥98% 2009-02-03 0.165745856354 qx-314-bromide lidocaine local anesthetic TRPV1 sodium channel blocker pain nociceptor capsaicin 0.165745856354
10011620 Raloxifene (hydrochloride) 82640-04-8 ≥98% 2009-01-07 6.465676795579 raloxifene-hydrochloride Evista; LY156758; Keoxifene (hydrochloride) breasts cancers osteoporosis SERM estrogen evista bone remodeling formation IL-6 IL6 25-OH vitamin D parathyroid hormones cardiovascular protection 6.465676795579
70600 REV 5901 101910-24-1 >98% 3.833245856353 rev-5901 leukotrienes receptors antagonists lipoxygenases inhibitors inhibits 3.833245856353
10096 SB 242084 (hydrochloride) 1049747-87-6 ≥98% 2010-06-29 1.280536700867 sb-242084-hydrochloride 181632-25-7 serotonins 5-hydroxytryptamines 5-HT neurotransmitters neuroscience receptors gut central nervous system antagonists 5-HT2C dopamine adrenergic receptors brain anxiolytic neurochemistry CNS Antigens HLA-SB Antigens HLA-PL Antigens HLA-DP HLA-SB Antigens HLA-PL Antigens HLA-DP Antigens HLA SB Antigens HLA PL Antigens HLA DP Antigens HLA-SB HLA-PL HLA-DP 1.280536700867
11019 SB 366791 472981-92-3 ≥98% 2011-10-13 9.380497237569 sb-366791 pain TRPV1 antagonists hyperalgesia receptors neurons central peripheral nerves terminals thermal mechanical hyperalgesia bone cancers ganglion SB366791 SB-366791 9.380497237569
14060 SC-19220 19395-87-0 >96% 61.538110497237 sc-19220 PGE2 antagonists antinociceptives EP1 receptors selective prostaglandins SC19220 SC 19220 61.538110497237
10011561 SC-51089 146033-02-5 ≥95% 2010-02-02 10.908080110497 sc-51089 CID132748 prostaglandins E2 PGE2 receptors EP1 pain antagonists analgesia glioma cells cancers tumors growth neuroprotection neurons oxidative stress SC51089 SC 51089 PGs Oxazepines 10.908080110497
10010744 SC-51322 146032-79-3 >98% 2010-03-09 17.113646408840 sc-51322 SC51322 SC 51322 prostaglandins E2 PGE2 receptors EP1 pain vasorelaxation inflammation PGs inflammatory signaling signalling antagonist Misoprostol, (11alpha,13Z)-(+-)-Isomer Misoprostol, (11beta,13E)-(+-)-Isomer Misoprostol (11alpha.13E,16S)-Isomer Misoprostol (11alpha,13E,16R)-Isomer Misoprostol, (11beta,13E,16S)-Isomer Misoprostol, (11beta,13E,16R)-Isomer Misoprostol (11alpha,13E)-Isomer Grunenthal Brand of Misoprostol Novopharm Brand of Misoprostol Misoprostol Grunenthal Brand Pfizer Brand of Misoprostol Misoprostol Novopharm Brand Apotex Brand of Misoprostol Misoprostol Pfizer Brand Misoprostol Apotex Brand Novo-Misoprostol Novo Misoprostol Apo-Misoprostol Apo Misoprostol Misoprostol SC-30249 SC-29333 SC 30249 SC 29333 SC30249 SC29333 Cytotec Glefos 17.113646408840
10008012 SPD-304 Exclusive 869998-49-2 ≥98% ✓ 2006-08-07 25.937527624309 spd-304 TNF-.alpha. TNF.alpha. signal transduction inflammation small-molecule inhibitor cytokine apoptosis NF-kB AP-1 inhibitor antagonist SPD304 SPD 304 CAY10500 CAY 10500 SPD00000304 SPD 00000304 25.937527624309
19025 SQ 29,548 98672-91-4 ≥98% 95.835127071823 sq-29-548 thromboxanes TXA2 SQ-29548 SQ29548 analogs TP antagonists receptors atherosclerosis 95.835127071823
10009022 (S)-SLV 319 Exclusive 464213-10-3 ≥98% ✓ 2007-08-16 0.254419889503 -s-slv-319 CB1 CB2 receptors cannabinoids antagonists inflammation obesity neurochemistry inflammatory neuro-inflammatory neuroinflammatory (S)-SLV319 disorders ligands 0.254419889503
10026 T0070907 313516-66-4 ≥98% 44.348055248618 t0070907 T-0070907 nuclear receptors antagonist PPARgamma PPAR.gamma. peroxisome proliferator-activated selective selectivity thiazolidinediones TZDs inhibits inhibition inhibitors atherosclerosis endocrinology 44.348055248618
11612 Tafluprost ethyl ester Exclusive New 209860-89-9 ≥98% ✓ 2012-04-20 137.247943523633 tafluprost-ethyl-ester AFP 175 AFP-175 AFP175 glaucoma intraocular pressure receptors agonists prostaglandins PGs analogs ophthalmology FP lipids tissues 137.247943523633
11629 Tamoxifen (citrate) New 54965-24-1 ≥98% 2012-04-04 71.420949142938 tamoxifen-citrate ICI 46474; Nolvadex; Istubal; Noltam; Kessar; TMX; Valodex; Zemide 7244-97-5 I.C.I.46474 citrate tamofen tamoplex tamox-puren tomaxasta Z-tamoxifen citrate nourytam ICI-46474 ICI46474 estrogen receptors cancers breasts agonists antagonists cholesterol modulators ER adjuvants bones uterus tissues cytochromes P450 CYP450 endoxifen cells apotosis autophagy differentiation 71.420949142938
10007565 Tetradecyl Phosphonate 4671-75-4 >98% 2005-10-17 49.791160220994 tetradecyl-phosphonate pan-antagonists LPA receptors lysophosphatic acids lipids signalling molecules hydrolysis lysophospholipase D autotoxin signals GPCRs G-protein coupled LPA1/EDG-2 LPA2/EDG-4 LPA3/EDG-7 LPA4/GPR23 activates activation PPAR.gamma. peroxisomes proliferator-activated inhibits inhibition LPA-induced calcium mobilization activates reporter 49.791160220994
10011127 Thioperamide Maleate 148440-81-7 ≥98% 2009-03-26 0.202209944751 thioperamide-maleate histamines H3 receptors antagonists seizures GABA 110-16-7 106243-16-7 selective croses blood-brain barrier 0.202209944751
60950 (±)trans-2,5-bis-(3,4,5-Trimethoxyphenyl)-1,3-dioxolane 116673-45-1 ≥98% 4.326817679558 -trans-2-5-bis-3-4-5-trimethoxyphenyl-1-3-dioxolane trans-BTP Dioxolane PAFs antagonists dioxolanes receptors platelet-activating factors (±)trans-2,4-bis-(3,4,5-Trimethoxyphenyl)-1,3-dioxolane 4.326817679558
70705 U-75302 119477-85-9 >98% 23.604364640884 u-75302 LTB4 receptors antagonists leukotrienes u75302 23.604364640884
10010992 W123 Exclusive - ≥98% ✓ 2008-11-14 61.497002762431 w123 FTY720 sphingosines sphingosine-1-phosphate receptors S1P S1P1 EDG1 EDG-1 inhibitors inhibits inhibition SEW2871 FTY 720 antagonist 61.497002762431
10009109 W146 (trifluoroacetate salt) - ≥95% 2010-03-10 75.952498465316 w146-trifluoroacetate-salt S1Ps sphingosine-1-phosphates sphingosines phosphates lymphocytes S1P1 antagonists immunity capillary leakage antagonists GPCR G protein-coupled receptors S1P2 S1P3 S1P5 TFA salts Phosphonic Acid Esters Phosphonic Acids Phosphonates 75.952498465316
10736 (±)WIN 55212 (mesylate) New 137795-17-6 ≥98% 2012-01-11 46.514430542014 -win-55212-mesylate cannabinoids CB1 CB2 receptors pain neuroscience agonists antagonists aminoalkylindole CBs enantiomers (+)WIN 55212-2 (-)WIN 55215-3 SR144528 SR-144528 SR 144528 racemic mesylate central peripheral 46.514430542014
13246 YM-58483 223499-30-7 ≥98% 2009-11-16 5.369171270719 ym-58483 BTP 2 calcium channels leukocytes leukotrienes eicosanoids inflammation asthma allergy IL-2 IL-4 lymphocytes eosinophils NF-AT CRACs CysLTs interleukin-4 BTP2 BTP-2 CysLT 5.369171270719
10008282 Zafirlukast 107753-78-6 ≥97% 2006-05-01 18.503117600631 zafirlukast Accolate® cysteinyl-leukotrienes cysLT1 receptors GPCRs protein-coupled antagonists asthma asthmatic allergies allergic rhinitis selective cysLTs cys-LTs cys-LT1 accolate™ 18.503117600631
71800 (Z)-Guggulsterone 39025-23-5 ≥98% 2009-12-01 1.169042357274 -z-guggulsterone anti flammatory cancers FXR bile acids LDL cholesterol tumors IL-6 STAT3 VEGF Akt 1.169042357274
Other Resources
Management Team Company Profile Company History ChemAssistant Tools FAQs Cayman Europe Cayman Pharma CaBRI Cayman Gear Press Releases Illustrations and Charts Key Research Area Posters Article Library Analysis Tools Conference Schedule Order Terms Browser Recommendation Privacy Statement Site Map

Cayman Chemical Company · 1180 East Ellsworth Road · Ann Arbor, Michigan 48108 · USA

Toll Free: (800) 364-9897 (USA and Canada Only) · Fax: (734) 971-3640

Copyright 2012 Cayman Chemical Company

Lost password?