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Join us! · InformexUSA 2012 · New Orleans, Louisiana · February 14-17, 2012 · Booth 2514

Chemical Class · Receptor Antagonist

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Item Number Product Sizes & Pricing CAS Purity Image Exclusive Introduction Date Mojo Plain Text Name Synonyms Keywords Interest
10010129 AG-041R Exclusive 199800-49-2 ≥98% ✓ 2008-12-16 40.045359116022 ag-041r CCKs gastrin receptors antagonist cancers proliferations apoptosis NS-398 NS398 NS 398 40.045359116022
13203 Agomelatine 138112-76-2 ≥98% 2009-11-06 3.236961325967 agomelatine Valdoxan® melatonin circadian rhythm MT1 MT2 serotonin 5-HT noradrenaline dopamine antidepressant anti-depressant S20098 S-20098 S 20098 3.236961325967
19023 AH 23848 (calcium salt, hydrate) - ≥90% 2009-02-26 56.043558011050 ah-23848-calcium-salt-hydrate AH23848B AH 23848 TXBs thromboxane PGEs PGE2 receptors prostanoids TPs EP4 antagonist blockers inhibitors inhibits inhibition TXA2 platelets smooth muscle bronchial U-46619 U46619 fibroblasts cancers metastasis 81739-45-9 AH-23848 56.043558011050
10006974 AM630 164178-33-0 ≥98% 2009-02-09 47.163132289748 am630 Iodopravadoline neurochemistry neuroscience cannabinoids CB1 CB2 antagonist inverse agonist antinociception pain receptors 47.163132289748
10009021 AVE-1625 Exclusive 358970-97-5 >98% ✓ 2008-04-03 121.810082872928 ave-1625 cannabinoids CB1 receptors schizophrenia parkinsons disease alzheimers disease metabolism obesity SR-141716 lipolysis glycogenolysis antagonist endocrinology neurochemistry 121.810082872928
10532 BayCysLT2 Exclusive 712313-33-2 ≥95% ✓ 2010-09-22 3.860902394106 baycyslt2 CAY10633 HAMI3379 cysLT2 receptors cardiovascular disease antagonists leukotrienes LTC4 LTD4 cysteinyl HAMI 3379 HAMI-3379 cyslts CAY10633 CAY-10633 CAY 10633 3.860902394106
10489 Candesartan cilexetil 145040-37-5 ≥98% 2011-04-08 7.204143646409 candesartan-cilexetil TCV-116 angiotensin II receptors antagonists hypertension diabetes AT1 type 1 stress diastolic blood pressure anti-hypertensive antihypertensive 7.204143646409
10007518 Capsazepine 138977-28-3 >98% 2006-03-29 10.181482504603 capsazepine vanilloid receptors 1 VR1 transient potential TRP endogenous stimuli tissues injury inflammation pain antagonists capsaicin Ca2+ neonatal rats dorsal root ganglias Chinese hamsters ovary ovaries cells 10.181482504603
16835 CAY10580 Exclusive 64054-40-6 ≥96% ✓ 2009-03-16 77.547532228361 cay10580 PGEs PGE2 receptors inhibitors inhibits inhibition antagonist blockers EP4 cAMPs bones fromation resorption cancers atherosclerosis 77.547532228361
10012553 CAY10595 Exclusive 916047-16-0 ≥97% ✓ 2009-07-08 9.510211786372 cay10595 DP2 PGD2 CRTH2 chemotaxis inflammation antagonists prostaglandins PGDs 9.510211786372
10012539 CAY10597 916046-55-4 ≥98% 2009-03-11 4.356453038674 cay10597 DP2 PGD2 CRTH2 chemotaxis inflammation antagonist 5-chloro-1'-[(2-fluorophenyl)methyl]-2,2',5'-trioxo-spiro[3H-indole-3,3'-pyrrolidine-1(2H)-acetic acid 4.356453038674
10820 CAY10651 Exclusive - ≥98% ✓ 2011-06-15 0.911602209945 cay10651 Glutamate neurotransmitters receptors mGlu5 pain anxiety antagonists gastresophageal reflux diseases dyskinesia fragile X syndromes drug addictions cortical astrocytes functional binding assays mobilization calcium CNS 0.911602209945
10011126 Clobenpropit (hydrobromide) 145231-35-2 >98% 2008-12-04 6.820027624309 clobenpropit-hydrobromide Carbamimidothioic Acid; VUF-9153 histamines receptors antagonist GABA neurons brains seizures 6.820027624309
13657 (±)-Clopidogrel (hydrochloride) 90055-48-4 ≥98% 2011-04-11 0E-12 -clopidogrel-hydrochloride platelets aggregation antagonists P2Y12 receptors ADPs prodrugs anti-thrombic antithrombic 0E-12
10011296 (E)-Guggulsterone 39025-24-6 ≥98% 2009-12-03 0.966850828729 -e-guggulsterone anti-flammatory cancers FXR bile acids LDL cholesterol antiinflammatory atherosclerosis obesity diabetes inflammation farnesoid X receptors guggul trees 0.966850828729
13841 GANT 61 500579-04-4 ≥98% 2011-04-20 102.909143646409 gant-61 NSC 136476 Hedgehog transcription factors genes expression GLI cancer glioblastomas antagonists development regulation GANT61 GANT-61 pyridines pyrimidines NSC136476 NSC-136476 TFs 102.909143646409
10009162 GW 627368X Exclusive 439288-66-1 ≥96% ✓ 2007-05-14 22.181139502762 gw-627368x EP4 receptor antagonist TP prostanoid prostaglandin platelets U-46619 aggregation PGE2 EP1 EP2 EP3 GW627368X GW-627368X 22.181139502762
10010410 GW 848687X 612831-24-0 ≥98% 2009-11-25 15.437038674033 gw-848687x Receptors EP1 PGE2 vasoconstriction bronchoconstriction hyperalgesia allodynia gastric protection relief hyperthermia sleep antagonists thromboxanes TP inflammation arthritis pain inflammatory GW848687X GW-848687X 15.437038674033
70785 GW 9662 22978-25-2 ≥98% 87.012878453038 gw-9662 GW-9662 GW9662 ligands ppar.gamma. ppargamma peroxisome proliferator-activated nuclear endocrinology receptors antagonists atherosclerosis 87.012878453038
9000497 GW 9662-d5 Exclusive - ≥99% deuterated product ✓ 2009-09-30 44.903296500920 gw-9662-d5 deuterateds deuterium GC/MS GC-MS LC/MS LC-MS mass spectrometry GW-9662 GW9662 ligands ppar.gamma. γ ppargamma peroxisome proliferator-activated nuclear endocrinology receptors antagonists atherosclerosis TZDs thiaolidinediones PPARs 44.903296500920
10580 HAMI3379 Exclusive 712313-35-4 ≥90% ✓ 2011-03-14 84.849629044987 hami3379 cysLT2 receptors cardiovascular diseases antagonists leukotrienes LTC4 LTD4 cysteinyl LTs CysLTs perfusion pressure decrease contractility cyclohexanecarboxylic acids 84.849629044987
10012699 JMV3002 Exclusive 925239-03-8 ≥98% ✓ 2009-03-11 86.936740331491 jmv3002 ghrelins obesity growth hormones foods intake receptors antagonists secretagouge hexarelin-stimulated secretion 86.936740331491
10011925 JNJ-7777120 459168-41-3 ≥98% 2011-02-24 2.119060773480 jnj-7777120 histamines H4 receptors antagonists inflammation Piperazines 2.119060773480
10009458 JTE-013 383150-41-2 ≥98% 2007-01-18 97.558465316145 jte-013 reverses inhibition inhibits coronary artery smooth muscles lipids cells proliferation cytoskeletal morphogenesis GPCRs protein-coupled receptors antagonists S1P2 humans rats EDG5 sphingosines sphingosine-1-phosphates sphingosine1 inhibitors JTE013 FDG-5 cancers 97.558465316145
10012659 Ki16425 355025-24-0 ≥95% 2008-11-06 131.153265807243 ki16425 LPA1 LPA2 LPA3 LPA4 LPA5 lysophosphatidic acids cancers antagonist receptors selective 131.153265807243
10011562 L-655,240 103253-15-2 ≥98% 2009-10-15 6.484599447513 l-655-240 platelet aggregation smooth muscle constriction contraction antagonist receptors TXA2 receptor TP thromboxane TPα TPβ TXA2 bronchoconstriction L-655240 L 655240 6.484599447513
13453 LH 21 611207-11-5 ≥98% 2011-03-22 17.263738489871 lh-21 cannabimimetic CBs cannabinoids CB1 receptors antagonists pain weight gain obesity LH-21 LH21 central 17.263738489871
10010024 LY223982 Exclusive 117423-74-2 ≥98% ✓ 2008-07-24 6.007845303868 ly223982 SKF 107324; CGS 23131 LTB4 receptors inflammation antagonist benzophenone neutrophil chemotaxis leukotriene B4 fatty acids 5-LO 5LO CGS23131 SKF107234 6.007845303868
10009768 LY293111 Exclusive 161172-51-6 ≥98% ✓ 2009-02-09 90.203204419890 ly293111 Etalocib; VML 295 LTBs LTB4 receptors inflammation antagonist benzophenone neutrophil chemotaxis pancreatic cancers 90.203204419890
10517 Naphyrone (hydrochloride) New 850352-11-3 ≥97% 2011-08-29 119.314385553262 naphyrone-hydrochloride O-2482; NRG-1; Naphpyrovalerone; β-Naphyrone analogs MDPV forensics sciences designer drugs 850352-53-3 pyrovalerones cathinones dopamine serotonins norepinephrines bath salts 119.314385553262
10004184 NESS 0327 Exclusive 494844-07-4 >98% ✓ 2008-05-27 38.872345554997 ness-0327 neurochemistry neuroscience cannabinoids antagonist CB1 CB2 SR 141716A rimonabant WIN 55212-5 pain obesity 38.872345554997
14070 ONO-8711 216158-34-8 ≥98% 2011-06-15 21.005331491712 ono-8711 ONO 8711 ONO8711 prostaglandins EPs EP1 receptors potent PGs antagonists AH-6809 AH 6809 AH6809 14060 14050 SC-19220 SC19220 SC 19220 21.005331491712
10011332 Plerixafor (hydrochloride hydrate) 155148-31-5 ≥98% 2009-02-10 58.760906077348 plerixafor-hydrochloride-hydrate Mobozil™; SID 791; JM 3100; AMD 3100 stem cells hematopoiesis HIV lymphocyte replication metastasis cancers growth antagonist CXCR4 SDF-1 SDF1 CXCL12 ireversible virus inhibits inhibition inhibitor 58.760906077348
10011620 Raloxifene (hydrochloride) 82640-04-8 ≥98% 2009-01-07 5.901491712706 raloxifene-hydrochloride Evista; LY156758; Keoxifene (hydrochloride) breasts cancers osteoporosis SERM estrogen evista bone remodeling formation IL-6 IL6 25-OH vitamin D parathyroid hormones cardiovascular protection 5.901491712706
9000484 Rimonabant 168273-06-1 ≥98% 2009-06-17 70.164019337016 rimonabant SR141716 SR 141716A SR141716A CB1 inverse agonists anti-obesity immunomodulation anti-proliferation appetite suppressants receptors weight control medication cannabinoids anti-proliferative immunodulatory cbs sythetic 70.164019337016
11019 SB 366791 New 472981-92-3 ≥98% 2011-10-13 5.295556823889 sb-366791 pain TRPV1 antagonists hyperalgesia receptors neurons central peripheral nerves terminals thermal mechanical hyperalgesia bone cancers ganglion SB366791 SB-366791 5.295556823889
10010744 SC-51322 146032-79-3 >98% 2010-03-09 14.510596685082 sc-51322 SC51322 SC 51322 prostaglandins E2 PGE2 receptors EP1 pain vasorelaxation inflammation PGs inflammatory signaling signalling antagonist Misoprostol, (11alpha,13Z)-(+-)-Isomer Misoprostol, (11beta,13E)-(+-)-Isomer Misoprostol (11alpha.13E,16S)-Isomer Misoprostol (11alpha,13E,16R)-Isomer Misoprostol, (11beta,13E,16S)-Isomer Misoprostol, (11beta,13E,16R)-Isomer Misoprostol (11alpha,13E)-Isomer Grunenthal Brand of Misoprostol Novopharm Brand of Misoprostol Misoprostol Grunenthal Brand Pfizer Brand of Misoprostol Misoprostol Novopharm Brand Apotex Brand of Misoprostol Misoprostol Pfizer Brand Misoprostol Apotex Brand Novo-Misoprostol Novo Misoprostol Apo-Misoprostol Apo Misoprostol Misoprostol SC-30249 SC-29333 SC 30249 SC 29333 SC30249 SC29333 Cytotec Glefos 14.510596685082
10009312 SKF-96365 (hydrochloride) 130495-35-1 >98% 2007-01-19 49.686806629834 skf-96365-hydrochloride calcium antagonists voltage-gated inhibits inhibitors inhibition acetylcholine-induced depolarization smooth muscles platelets neutrophils SFK9635 Ach-induced HCl neurochemistry 49.686806629834
10008012 SPD-304 Exclusive 869998-49-2 >98% ✓ 2006-08-07 19.841215469613 spd-304 TNF-.alpha. TNF.alpha. signal transduction inflammation small-molecule inhibitor cytokine apoptosis NF-kB AP-1 inhibitor antagonist SPD304 SPD 304 CAY10500 CAY 10500 SPD00000304 SPD 00000304 19.841215469613
10026 T0070907 313516-66-4 >98% 65.236381215470 t0070907 T-0070907 nuclear receptors antagonist PPARgamma PPAR.gamma. peroxisome proliferator-activated selective selectivity thiazolidinediones TZDs inhibits inhibition inhibitors atherosclerosis endocrinology 65.236381215470
10011127 Thioperamide Maleate 148440-81-7 ≥98% 2009-03-26 0.960497237569 thioperamide-maleate histamines H3 receptors antagonists seizures GABA 110-16-7 106243-16-7 selective croses blood-brain barrier 0.960497237569
13261 URB447 Exclusive 1132922-57-6 ≥98% ✓ 2009-06-18 32.550309392265 urb447 CB1 CB2 cannabinoids antagonists obesity SR 141716A SR141716A rimonabant blood brains barrier URB appetite suppressant receptors URB-447 URB blocking peptides 447 cannabinoids cbs synthetic 32.550309392265
10009109 W146 (trifluoroacetate salt) - ≥95% 2010-03-10 73.109797421730 w146-trifluoroacetate-salt S1Ps sphingosine-1-phosphates sphingosines phosphates lymphocytes S1P1 antagonists immunity capillary leakage antagonists GPCR G protein-coupled receptors S1P2 S1P3 S1P5 TFA salts Phosphonic Acid Esters Phosphonic Acids Phosphonates 73.109797421730
10736 (±)WIN 55212 (mesylate) New 137795-17-6 ≥98% 2012-01-11 110.382203395478 -win-55212-mesylate cannabinoids CB1 CB2 receptors pain neuroscience agonists antagonists aminoalkylindole CBs enantiomers (+)WIN 55212-2 (-)WIN 55215-3 SR144528 SR-144528 SR 144528 racemic mesylate central peripheral 110.382203395478
71800 (Z)-Guggulsterone 39025-23-5 ≥98% 2009-12-01 0.489963167587 -z-guggulsterone anti flammatory cancers FXR bile acids LDL cholesterol tumors IL-6 STAT3 VEGF Akt 0.489963167587
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