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Holiday Notification: Cayman Chemical will be closed Monday, May 28, 2012, in observance of the Memorial Day holiday. More…
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Research Area · Signal Transduction

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Item Number Product Sizes & Pricing CAS Purity Image Exclusive Introduction Date Mojo Plain Text Name Synonyms Keywords Interest
10008646 1,2-Dihexanoyl-sn-glycerol Exclusive 30403-47-5 ≥95% ✓ 2007-08-29 3.901988950276 1-2-dihexanoyl-sn-glycerol PKCs second messengers diacylglycerols DAG 1,2-dioctanoyl-sn-glycerols proteins kinases snglycerol 3.901988950276
10007863 1,2-Dioleoyl-rac-glycerol 2442-61-7 ≥95% 2010-11-10 1.801878453039 1-2-dioleoyl-rac-glycerol (±)-1,2-Diolein; rac-Glycerol 1,2-dioleate diacylglycerols DAGs proteins kinases C PKCs DGKs multisubstrates lipids MuLK 1,2-Di(cis-9-octadecenoyl)-rac-glycerol rac-1,2-dioleoylglycerol Diacylglycerols Diglycerides 1.801878453039
10008648 1,2-Dipalmitoyl-sn-glycerol 30334-71-5 ≥95% 2008-06-25 4.114585635359 1-2-dipalmitoyl-sn-glycerol NSC 269964; 1,2-DPG PKC proteins kinases C DAG activator 4.114585635359
13532 17-phenyl trinor Prostaglandin E2 ethyl amide Exclusive - ≥98% ✓ 2010-05-04 345.648555643251 17-phenyl-trinor-prostaglandin-e2-ethyl-amide 17-phenyl trinor PGE2 ethyl amide 17-phenyl trinor PGE2 agonists EP1 EP3 receptors EP4 smooth muscles contraction fertility prostaglandins PGs 345.648555643251
13812 17β-hydroxy Wortmannin Exclusive - ≥98% ✓ 2010-05-18 14.370954914398 17-hydroxy-wortmannin phosphoinositide 3-kinase PI3K mTOR inhibitors inhibits inhibition inhibitory cancers 17-hydroxywortmannins 17-hydroxy wortmannins hydroxywortmannins PI3-K HWT phosphatidylinositol 14.370954914398
10954 1-NA-PP1 221243-82-9 ≥98% 2011-09-30 56.814033149171 1-na-pp1 1-Naphthyl-PP1; PP1 Analog inhibitors inhibits inhibition kinases mutated analogs sensitive v-Src vSrc c-Fyn cFyn CDK2 c-Abl cAbl mammalian yeast 1NMPP1 1NA-PP1 cells permeable tyrosine cell-permeable AS Src-family Src I338G v-Src-AS1 56.814033149171
13330 1-NM-PP1 221244-14-0 ≥95% 2009-07-22 61.845267034990 1-nm-pp1 PP1 Analog II inhibitors inhibits inhibition kinases mutated analogs sensitive v-Src vSrc c-Fyn cFyn CDK2 CAMKII mammalian yeast 1NMPP1 61.845267034990
10007072 1-Palmitoyl-2-linoleoyl PE 26662-95-3 ≥98% 2005-12-20 21.209455406471 1-palmitoyl-2-linoleoyl-pe PLPE; Phosphatidyl Ethanolamine (1-palmitoyl, 2-linoleoyl) phosphoethanolamines phosphatidylethanolamines lipids biosynthesis lysophospholipases anandamides biochemical pathways fatty acids cellular membranes A2 D substrates sPLA2-IIA 21.209455406471
10008650 1-Stearoyl-2-Arachidonoyl-sn-Glycerol 65914-84-3 >95% 2008-04-04 5.513508287292 1-stearoyl-2-arachidonoyl-sn-glycerol SAG signal transduction PKCs DAGs .omega.6 PUFA RasGRP ERK MAPK fatty acids signalling signaling activators diacylglycerols 5.513508287292
10009872 1-Stearoyl-2-Arachidonoyl-sn-Glycerol-d8 Exclusive - ≥99% deuterated forms (d1-d8) ✓ 2008-12-04 3.580220994474 1-stearoyl-2-arachidonoyl-sn-glycerol-d8 SAG-d8 deuterium GC/MS internal isotopes standards ethanolamides GC-MS LC/MS LC-MS mass spectrometry deuterated 3.580220994474
10005707 (2S)-OMPT - ≥98% 2005-10-19 33.258149171270 -2s-ompt GPR lysophosphatidic acids lipids mediators receptors LPA1/Edg-2 LPA2/Edg-4 LPA3/Edg-7 LPA4/GPR23 agonists calcium mobilization Sf9 cells (2R)-OMPT release assays LPA3-transfected rat hepatoma Rh7777 33.258149171270
10727 3,5-dimethyl PIT-1 701947-53-7 ≥98% 2011-05-25 12.344984039287 3-5-dimethyl-pit-1 PIP3 PtdIns-(3,4,5)-P3 PH domain cancers inhibitors Akts PDK1 PTENs proteins binding inhibits inhibited inhibition DM-PIT-1 12.344984039287
10009804 3-PT-PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt) - ≥98% 2009-03-20 14.384475138121 3-pt-ptdins-3-4-5-p3-1-2-dioctanoyl-sodium-salt 3-Phosphorothioate-Phosphatidylinositol-4,5-diphosphate C-8 3-PT-PtdIns(3,4,5)-P3 PtdIns(3,4,5)-P3 PTEN PIP PIP(3,4,5) cells signaling PI3 kinases cancers phosphatidyl inositols phosphates membrane phospholipids signalling sodium transport 14.384475138121
10010375 5-Iodotubercidin 24386-93-4 ≥95% 2008-01-24 53.323775322284 5-iodotubercidin Itu; NSC 113939 adensosine glycogen hepatocytes phosphorylase .alpha. glycogen synthase .alpha. kinases protein kinase A casein kinases II casein kinases I protein kinase C phosphorylase kinases EFK2 MAPK1 cell proliferations fatty acid oxidations lipogenesis acetyl-CoA carboxylase 53.323775322284
10009856 7-AAD Cell Viability Assay Kit - 2008-10-29 22.474749868935 7-aad-cell-viability-assay-kit 7-Amino Actinomycin D Cell Viability Kit kits 7AAD measurement cells fixation blocking cytoxicity effects environmental toxins drug fluorescence fluorescent cell-based assays cell based assay cba 22.474749868935
9000530 7(Z)-Pentacosene Exclusive 63623-49-4 ≥98% ✓ 2009-12-03 19.740342541436 7-z-pentacosene pheromones fruits flies Drosophilia copulation hydrocarbon 7-pentacosene (Z)-7-pentacosene cis-7-pentacosene 7-cis-pentacosene 19.740342541436
9000313 7(Z)-Tricosene Exclusive 52078-42-9 ≥98% ✓ 2009-03-15 28.813867403314 7-z-tricosene fruits fly flies pheromone drosophila bombus hydrocarbon 28.813867403314
10010109 8-DY547-cGMP - ≥98% 2008-10-23 774.385911602210 8-dy547-cgmp CNGA2 channels activators fluorescences cyclic nucleotides 774.385911602210
11016 A-23187 52665-69-7 ≥98% 2011-10-25 9.320244672454 a-23187 Calcimycin calcium cells activations ionophore signaling apoptosis antibiotic A23187 A 23187 37259-87-6 37263-57-3 51257-80-8 51310-65-7 53095-21-9 9.320244672454
13653 ABT-869 796967-16-3 ≥98% 2010-12-09 38.810202578269 abt-869 Linifanib inhibitors RTK tyrosine kinases VEGF PDGF cancers KDR Flt1 Flt3 Flt4 CSF-1R KIT acute myeloid leukemia antiproliferative anti-proliferative ABT 869 ABT869 Indazoles 38.810202578269
13297 AG-126 118409-62-4 ≥95% 2009-07-14 5.198800315706 ag-126 Tyrphostin AG-126 tyrphostins proteins tyrosine inhibitors inhibits inhibition cells growth epidermal growth factors receptors kinase GFRK EGFs EGFRK PDGF PDGFRK platelet-derived platelet derived phosphorylation ERK1 p44 ERK2 p42 TNF-α TNFα TNF α NF-κB NFκB NF κB COX-2 COX2 iNOS inflammation 5.198800315706
10010568 AG-370 134036-53-6 >95% (cis/trans mixture) 2009-01-09 1.229594843462 ag-370 NSC 651712 PTK inhibitor tyrphostin tyrosine PDGF receptor kinase EGF receptor antiproliferative 1.229594843462
10010243 AG-825 149092-50-2 ≥98% 2008-01-24 2.012059984214 ag-825 Tyrphostin AG-825 Her-2 Her-2/neu erbB tyrosine kinases EGF EGFR cancers anti-cancer prostate breast signal transduction inhibitors inhibition inhibits AG825 AG 825 2.012059984214
10793 AG-879 148741-30-4 ≥95% 2011-05-06 2.752812154696 ag-879 Tyrphostin AG-879 PTKs inhibitors tyrphostins tyrosine kinases antiproliferative NGF TrkA ErbB2 FLK-1 AG879 AG 879 inhibited inhibition 2.752812154696
13735 Akt2/3 Polyclonal Antibody - 2010-01-12 1.083188634569 akt2-3-polyclonal-antibody Akt-2 Akt 2 PKB proteins kinase B serine threonine signaling PI3-kinase cancers Western blots blotting immunoblotting WB Akt-3 Akt 3 2-3 1.083188634569
13734 Akt2 Monoclonal Antibody (Clone 95C567.1.2) - 2010-01-12 1.083188634569 akt2-monoclonal-antibody-clone-95c567-1-2 Akt-2 Akt 2 PKB proteins kinase B serine threonine signaling PI#-kinase cancers Western blots blotting immunoblotting WB 1.083188634569
10010079 Akt (human recombinant) Western Ready Control Exclusive - ✓ 2008-08-26 3.961519337016 akt-human-recombinant-western-ready-control Protein Kinase B; PKB; AKT1 western blots proteins antibodies antiserum antisera WB kinases serine threonine hexahistidine his-tag his-tagged N-terminal immunoblotting blotting 3.961519337016
10007466 Arachidonic Acid-biotin - >98% 2005-11-30 26.445758133824 arachidonic-acid-biotin fatty acids PUFAs polyunsaturated biotinylated affinity probes binding proteins cellular cells esterified membranes phospholipids regulated pathways substrates biosynthesis eicosanoids messengers receptor-stimulated release metabolisms re-uptake signalling inflammation detection detected complexes elucidations transports FABPs biotins biotinylated 26.445758133824
13495 ARAP2 Polyclonal Antibody - 2009-09-03 1.089779005524 arap2-polyclonal-antibody Centaurin-δ-1 antibodies proteins A chromatography WB western blots immunoblotting IHC immunohistochemistry blotting 1.089779005524
13496 AROS Polyclonal Antibody (aa 1-50) - 2009-09-03 0E-12 aros-polyclonal-antibody-aa-1-50 WB western blots immunoblotting protein nucleolar RPS19 cDNA chromosome 22q13.1 antibodies blotting 0E-12
13498 ARRB2 Polyclonal Antibody - 2009-09-22 42.829944751381 arrb2-polyclonal-antibody β-Arrestin-2 WB IHC western blots blotting immunoblotting antibodies immunohistochemisty ARRB-2 βarrestin2 β-arrestin2 β arrestin 2 β2R receptors adrenergic 42.829944751381
13622 AS-041164 Exclusive 1146702-72-8 ≥98% ✓ 2010-01-25 14.118729281768 as-041164 phosphoinositides 3-kinases PI3K cells growth migration metabolism inhibitors inhibits PI3Kα PI3Kβ PI3Kγ PI3Kδ chemotaxis inflammation neutrophils AS041164 AS-041164 RANTES 14.118729281768
10009052 AS-252424 900515-16-4 ≥95% 2007-01-30 25.573676284018 as-252424 phosphoinositides 3-kinases PI-3 PI3-K Phosphatidylinositol inhibitors PI3K .gamma. inhibition inhibitory PtdIns AS252424 25.573676284018
10007707 AS-605240 648450-29-7 >98% 2007-06-13 15.216846364194 as-605240 phosphoinositide 3-kinases PI3-kinase PI3-K PI3K phosphoinositide phosphatidylinositols inibitors inflammation arthritis rheumatoid peritonitis neutrophils recruitment as605240 15.216846364194
9000980 AS-605240 (potassium salt) Exclusive - ≥98% ✓ 2011-03-25 14.786789441375 as-605240-potassium-salt phosphoinositides 3-kinases PI3-kinases PI3-K PI3K phosphatidylinositols inhibitors inflammation arthritis rheumatoid peritonitis neutrophils recruitment as605240 as 605240 PIs salts solubility soluble 14.786789441375
11226 AS-703026 New 1236699-92-5 ≥98% 2012-03-08 27.541067090939 as-703026 MSC1936369B AS 703026 AS703026 1204531-26-9 MEKs MEK1/2 MEK-1/2 MEK1 MEK2 ERKs Ras Raf inhibitors inhibits inhibitions cancers multiple myeloma EGFR signals transductions kinases cells biology 27.541067090939
10009410 ATF2 (Phospho-Ser490,498) Polyclonal Antibody - 2006-11-28 1.522790055248 atf2-phospho-ser490-498-polyclonal-antibody Activating Transcription Factor 2 wb western blotting blots ihc immunohistochemistry antibodies activating transcriptional factors CRE-BP1 AP-1 DNA response elements ATF/CREB leucine zipper proteins regulating regulation genes cytokines cells cycles controls apoptosis death cellular stress inflammatory UV irradiation activity phosphorylation serines brains substrates neuronal neurons growth differentiation human depression phospho-specific immunoblotting 1.522790055248
600140 Autophagy/Cytotoxicity Dual Staining Kit - 2009-07-14 80.606732438832 autophagy-cytotoxicity-dual-staining-kit assays kits measuring measurement MDC cell-based autophagy cells cytotoxicity staining autofluorescent autofluorescence substances multilamellar body bodies ions trapping mechanisms membranes lipids probes autophagic vacuoles cultured degradation digestion intracellular lysosomes organelles misfolded proteins microorganisms cytoplasms double membranes autophagosomes autolysosomes homeostasis dysregulation cancers infections aging degenerative diseases stress death apoptosis 80.606732438832
10011336 Avenanthramide-C methyl ester Exclusive 955382-52-2 ≥95% ✓ 2009-06-18 63.084175874769 avenanthramide-c-methyl-ester Inhibitors NF-κB IL-6 IL-8 MCP-1 IκB inhibits inhibition Interleukins 63.084175874769
13823 AX 048 Exclusive 873079-69-7 ≥98% ✓ 2010-09-15 7.192651933702 ax-048 Inflammation antihyperalgesia cPLA2 phospholipases inhibitors inhibition inhibits AX048 AX-048 signaling signalling group IVA PLA2 cannabinoids cbs synthetic Acids Octanoic Octanoic Acids 7.192651933702
10011131 BAY-41-8543 Exclusive 256498-66-5 ≥98% ✓ 2009-11-16 19.971519337016 bay-41-8543 soluble guanylate cyclase sGC nitric oxide NO GTP cyclic GMP cGMP agonist stimulator platelet aggregation blood pressure bleeding time thrombosis pulmonary hypertension BAY 41-8543 BAY 41 8543 19.971519337016
10011135 BAY-60-7550 439083-90-6 ≥95% 2009-03-13 55.561077348066 bay-60-7550 inhibitors inhibits inhibition cyclic nucleotides cGMP cAMP cells signalling signaling PDE2 memory memories phosphodiesterase 55.561077348066
13123 BIO 667463-62-9 ≥98% 2009-06-09 39.414977398292 bio GSK 3 IX; MLS 2052 GSK-3α GSK-3β inhibitors Cdk cells cycle wnt ESCs differentiation embryonic stem GSK-3a/b GSK3a/b 39.414977398292
10005836 bis(7)-Tacrine 224445-12-9 >98% 2005-04-15 6.130883977900 bis-7-tacrine 1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydro-acridine dimeric congeners amino acridines inhibits inhibitors inhibition acetylcholinesterases Alzheimer's disease hydrogen peroxides apoptosis pheochromocytoma cells neurochemistry neuroscience 6.130883977900
13298 Bisindolylmaleimide I 133052-90-1 ≥95% 2009-08-28 25.781082722961 bisindolylmaleimide-i Gö 6850; GF 109203X; BIM 634199-82-9 682340-45-0 inhibitors inhibits inhibitions PCK GSK-3 GSK3 staurosporine 5-HT3 receptors 5HT3 Go 6850 25.781082722961
11020 Bisindolylmaleimide II New 137592-45-1 ≥97% (isomer mixture) 2012-03-13 33.836712196878 bisindolylmaleimide-ii PKC staurosporines inhibitors inhibits inhibition PDK1 PKA kinases C PKCα signaling insulin ligands binding protein kinase C 33.836712196878
13299 Bisindolylmaleimide IV 119139-23-0 ≥98% 2009-07-29 12.639200145022 bisindolylmaleimide-iv Arcyriarubin A PKC PKA staurosporine inhibitors 634199-73-8 12.639200145022
11073 Bisindolylmaleimide XI (hydrochloride) New 145333-02-4 ≥98% 2012-03-21 37.214390955495 bisindolylmaleimide-xi-hydrochloride Ro 32-0432 131848-98-1 Ro32-0432 Ro-32-0432 Ro-320432 Ro 320432 Ro320432 PKC isozymes Staurosporine inhibitors inhibits inhibition proteins kinases C PKCα PKCβI PKCε hydrochloride HCl cells hearts T-cell T cell inflammatory inflammation 37.214390955495
13186 (±)-Blebbistatin 674289-55-5 ≥98% 2009-06-09 62.848453038674 -blebbistatin inhibitors muscles myosin ATPase smooth bleb apoptosis cells migration chemotaxis cytokinesis division growth UV lights 62.848453038674
10681 C-16 Ceramide 24696-26-2 ≥98% 2011-03-08 3.761353591160 c-16-ceramide Palmitoyl Ceramide sphingomyelins apoptosis ceramides lipids membranes second messengers C16 ceramides longevity assurance homologs 6/LASS6 Ceramides C 16 3.761353591160
10724 C-20 Ceramide 7344-02-7 ≥98% 2011-03-08 3.692948895028 c-20-ceramide sphingomyelins apoptosis differentiation brains C20-ceramide C20:0 ceramides 20:0 synthesis 1 2 synthases 3.692948895028
10007518 Capsazepine 138977-28-3 ≥98% 2006-03-29 58.537209944750 capsazepine vanilloid receptors 1 VR1 transient potential TRP endogenous stimuli tissues injury inflammation pain antagonists capsaicin Ca2+ neonatal rats dorsal root ganglias Chinese hamsters ovary ovaries cells 58.537209944750
13702 Cav1.2 Calcium Channel Monoclonal Antibody (Clone S57-46) - 2009-11-05 1.281767955801 cav1-2-calcium-channel-monoclonal-antibody-clone-s57-46 antibodies western blotting blots immunoblotting WB immunohistochemistry IHC immunocytochemistry ICC channels ions fusion proteins gated voltage-gated ligand-gated voltage ligand 1.281767955801
13703 Cav1.3 Calcium Channel Monoclonal Antibody (Clone S38-8) - 2009-11-05 1.281767955801 cav1-3-calcium-channel-monoclonal-antibody-clone-s38-8 antibodies channels ions fusion proteins CACNAID western blots blotting immunoblotting WB immunohistochemistry IHC immunocytochemistry ICC gated voltage-gated ligand-gated voltage ligand 1.281767955801
13700 Cavβ1 Calcium Channel Monoclonal Antibody (Clone S7-18) - 2009-10-24 1.281767955801 cav-1-calcium-channel-monoclonal-antibody-clone-s7-18 antibodies western blotting immunoblotting WB IHC ICC IF immunohistochemistry immunocytochemistry immunofluorescence perox ions channels membrane proteins voltage ligands gated 1.281767955801
13701 Cavβ4 Calcium Channel Monoclonal Antibody (Clone S10-7) - 2009-11-05 1.281767955801 cav-4-calcium-channel-monoclonal-antibody-clone-s10-7 western blots blotting immunoblotting WB immunohistochemistry IHC immunocytochemistry ICC ions channels antibodies epilepsy IGE JME subunits gated voltage-gated ligand-gated ligand voltage 1.281767955801
10009078 CAY10505 328960-84-5 ≥98% 2009-11-04 7.700023327194 cay10505 phosphoinositide 3-kinase immunity autoimmune inflammation PI3Kγ PI3Kα PI3Kβ PI3Kδ casein kinases 2 CK2 phosphorylation PKB/Akt macrophages neutrophil recruitment cancer PI3s T2Ds PI3Ks PI3K.gamma. PI3Kg 7.700023327194
10010043 CAY10561 Exclusive 933786-58-4 ≥98% ✓ 2008-03-06 13.732486187846 cay10561 Pyrazolylpyrrole ERK Inhibitor MEK Ras Raf ERK2 proliferation cell cycles cancers apoptosis inhibition inhibit inhibitors 13.732486187846
10010233 CAY10567 32387-96-5 ≥98% 2008-05-06 3.418232044199 cay10567 BML-257 Akt1 inhibitors inhibits inhibition translocations HCV hepatitis signal transduction signaling signalling 3.418232044199
10010400 CAY10571 152121-46-5 ≥95% 2008-08-11 20.886629834254 cay10571 MAPK signal transduction p38 kinases heat shock cytokines inflammation immuno response CSAID CSBP UL-1 IL1 5-LO 5LO 20.886629834254
10011247 CAY10574 140651-18-9 >95% 2008-09-04 13.999403314917 cay10574 CDK2 cyclin E CDK9 inhibitors inhibits inhibition anticancer cell cycle CAN508 13.999403314917
10011248 CAY10575 916985-21-2 ≥95% 2008-09-03 24.234925019731 cay10575 IKKε IKK-ε IKK-e IKKe NFkB inflammation immune response cytokine kinase inhibitors inhibits inhibition NF-κB 24.234925019731
10011256 CAY10577 300675-28-9 ≥95% 2008-09-02 0.613259668508 cay10577 inhibitors inhibits inhibition CK2 kinase cell signaling apoptosis cancers 0.613259668508
10011264 CAY10578 19231-60-8 ≥95% 2008-08-26 0.613259668508 cay10578 inhibitors inhibits inhibition kinase cell signaling CK2 apoptosis cancers isoindolineacetic acids 0.613259668508
13206 CAY10593 Exclusive - ≥95% ✓ 2009-09-03 34.926662983425 cay10593 VU0155069 inhibitors inhibits inhibitions phospholipases D PLD PLD1 PLD2 phosphatidic acids PAs chemotaxis cells migration cancers breast lines tumors trans well assays 1130067-06-9 34.926662983425
13207 CAY10594 Exclusive 1130067-34-3 ≥98% ✓ 2009-06-23 25.943215469613 cay10594 Phospholipase D PLDs PLD1 PLD2 phosphatidic acid PA inhibitors chemotaxis cells migration cancers breast cancer inhibition inhibited 25.943215469613
13281 CAY10598 Exclusive 346673-06-1 ≥98% ✓ 2010-05-07 55.690121546961 cay10598 Prostaglandins E2 PGE2 receptors EP4 bone formation cancers atherosclerosis agonists EP1 EP2 EP3 DP FP IP TP neuroprotection renal dysfunction inflammation neuro-protection 55.690121546961
13358 CAY10608 Exclusive 457897-92-6 ≥98% ✓ 2010-04-29 1.305248618784 cay10608 N-Methyl-D-aspartate NMDA receptors antagonists glutamate glycine propanolamine NR2B subunit AMPA kainate neuroprotection neurochemistry antagonizes potently selectively non-competitively 1.305248618784
13687 CAY10622 Exclusive 1038549-25-5 ≥98% ✓ 2010-10-18 20.910441988950 cay10622 Rho kinases ROCK-I ROCK-II inhibitors inhibits inhibition 20.910441988950
13838 CAY10626 Exclusive 1202884-94-3 ≥98% ✓ 2010-08-23 12.047810517699 cay10626 PI3Kα mTOR cancers signal transduction inhibitors inhibits inhibition phosphatidylinositol 3-kinase PtdIns PIs 12.047810517699
10743 CAY10650 Exclusive 1233706-88-1 ≥98% ✓ 2011-06-14 12.111933701657 cay10650 cPLA2α cPLA2 inhibitors inflammation anti-inflammatory dermatitis metabolite phospholipase cytosolic prostaglandins PGs leukotrienes synthesis 10662 CAY-10650 CAY10641 CAY-10641 12.111933701657
10787 CCG-100602 1207113-88-9 ≥98% 2011-11-22 6.028416206261 ccg-100602 Rho signaling signal transduction cancers inhibitors SRF serum response factors transcription CCG-1423 megakaryoblastic leukemia 1 MKL1 prostate analogs PC-3 CCG100602 CCG 100602 CCG1423 CCG 1423 cells DNA binding RHOA/C-mediated MKL-1 6.028416206261
10010350 CCG-1423 285986-88-1 ≥98% 2007-09-20 10.328705603788 ccg-1423 Rho signaling transduction cancers proliferations anti-proliferation anti-tumor serum response factor GTPase inhibits inhibitors inhibition signalling 10.328705603788
13322 CGP 57380 522629-08-9 ≥95% 2009-08-28 32.518664825046 cgp-57380 MNK1 Inhibitor inhibitors inhibits inhibitions MAPKs MAP kinases interacting interacting-kinase 1 MNK1 p38 JNK1 ERK1/2 PKC Src-like phosphorylation elF4E TNF-a TNF-α TNFα TNFa arsenite anisomycin PMA fetal calf serum 293 cells RAW264.7 toll-like receptors TLR2 HKLM TLR4 LPS TLR6/2 FSL TLR7 imiquimod TLR9 CpG DNA CGP57380 CGP-57380 32.518664825046
11314 Chelerythrine chloride New 3895-92-9 ≥98% 2012-01-31 6.179201541034 chelerythrine-chloride NSC 646662; Broussonpapyrine chloride 6004-02-0 84282-43-9 chelerythrinium inhibitors inhibits inhibition PKC apoptosis cells signaling BclXL Bcl-2 cancers tumors p38 MAP kinases proteins JUNK benzophenanthridine alkaloids AC328200010 hydrochloride chlorid EINECS 223-444-9 2234449 3895-92-9 NSC 36405 NSC-36405 NSC36405 6.179201541034
13686 Chidamide 743420-02-2 ≥98% 2010-08-10 39.909907100471 chidamide HDACs histones deacetylase H3 acetylation colons cancers cells inhibitors inhibits inhibiton LoVo HT-29 HT29 HT 29 cycle arrest chidamides oncogenic signalling signaling kinases Benzamides 39.909907100471
13122 CHIR99021 252917-06-9 ≥98% 2011-02-18 100.590852407261 chir99021 CT 99021 GSK-3α GSK-3β inhibitors glucose metabolism insulin diabetes Wnt stem cells mice mouse CHIR-99021 CT-99021 CHIR 99021 CT99021 pyridines glucogen synthesis CHO-IR self-renewal 100.590852407261
581001 Cyclic AMP EIA Kit - 872.474818837547 cyclic-amp-eia-kit Adenosine 3',5'-cyclic monophosphate EIA Kit; cAMP EIA Kit; Adenosine 3',5'-cyclic mononucleotide EIA Kit; Cyclic AMP ELISA Kit solid plates cAMP adenosine measures kits eias enzyme immunoassays ELISAs second messengers neurochemistry neuroscience endocrinology assays 872.474818837547
581002 Cyclic AMP EIA Kit (without Acetic Anhydride) - 697.637638121547 cyclic-amp-eia-kit-without-acetic-anhydride cAMP EIA Kit (without Acetic Anhydride); Adenosine 3',5'-cyclic monophosphate EIA Kit (without Acetic Anhydride); Adenosine 3',5'-cyclic mononucleotide EIA Kit (without Acetic Anhydride); Cyclic AMP ELISA Kit (without Acetic Anhydride) solid plates cAMP adenosine measures kits eias enzyme immunoassays ELISAs second messengers neurochemistry neuroscience endocrinology assays 697.637638121547
11321 Cyclopamine New 4449-51-8 ≥98% 2012-02-20 28.356167127071 cyclopamine Jervine; 11-Deoxojervine 11051-96-0 26108-61-2 veratraman 11-deoxyjervine 11 deoxyjervine hedgehogs development teratogen cancers smoothened inhibitors cyclopia genes expressions signal transduction inhibits inhibition signaling steroids alkaloids pathways pax7 28.356167127071
11326 Cyclopiazonic Acid New 18172-33-3 ≥95% 2012-02-23 38.231529337214 cyclopiazonic-acid NSC 117181 inhibitors SERCA calcium Ca2+-ATPase ATPases smooth muscles endothelial cells endothelium cardiovascular vascular biology cardiology mycotoxins Penicillium Aspergillus NSC117181 NSC-117181 38.231529337214
13305 D 4476 301836-43-1 ≥98% 2009-07-29 39.871657458563 d-4476 Casein Kinase I Inhibitor inhibitors inhibits inhibition casein kinases 1 CK1 Ck1δ TGF-β TGFβ type-1 receptors ALK5 PKD1 p38α MAPK kinases phosphorylation FOXO1a RhoB p53 Smad3 D4476 39.871657458563
13197 DAPT 208255-80-5 ≥95% 2010-09-16 16.308718232044 dapt GSI-IX amyloids precursors proteins APP Notch beta amyloid Aβ Alzheimer’s disease inhibitors inhibits inhibition γ-secretase Aβ42 cells signaling signals differentiation GSIIX GSI IX Dipeptides 16.308718232044
13382 DAz-2 1176905-54-6 ≥98% 2009-11-05 30.426515738447 daz-2 DCP-N3 Daz1 Daz-1 Daz 1 sulfenic acids click chemistry ROS oxidative stress cysteine oxidation LC-MS/MS analysis standinger DCPN3 DCP N3 azoospermia protein 2 genes redox sensitive cysteine ROS oxidative modification stress signaling cells hydrogen peroxide alkyl hydroperoxides peroxynitrite adducts dimedone biotin fluorophores labels labeling lysis staudinger ligation LC-MS MS LC analysis sulphenic acids 30.426515738447
10010706 (−)-Deguelin 522-17-8 ≥98% 2008-09-18 42.460497237569 -deguelin (-)-cis-Deguelin rotenoids flavonids cancers antiproliferative chemoprevention parkinsons diseases Akt PKB PI3K COX-2 COX2 apoptosis PI3-K 42.460497237569
10007945 D-erythro-Sphinganine 764-22-7 ≥98% 2010-08-10 15.444741336011 d-erythro-sphinganine D-erythro-Dihydrosphingosine ceramide sphingosine sphingosine kinases sphinganine-1-phosphates mycotoxins fumonisins cancers protein kinase C PKC spingosine-1-phosphates cell signaling octadecasphinganine Dihydro-C18-sphingosine SPC 102860 SPC102860 signalling SPC-102860 15.444741336011
10007903 D-erythro-Sphingosine C-20 6918-49-6 ≥98% 2008-11-21 10.081802486187 d-erythro-sphingosine-c-20 sphingosines sphingolipids ceramides C-18 C18 C20 gangliosides brain development neurodegenerations 10.081802486187
11015 Dexamethasone 50-02-2 ≥98% 2011-10-25 23.483646408839 dexamethasone MK 125; NSC 34521 steroids hormones glucocorticoid agonist receptors inflammation genes expression anti-inflammatory antiinflammatory anti inflammatory 8054-59-9 137098-19-2 906362-70-7 906422-84-2 1050677-47-8 adexone aeroseb-Dex aphtasolon aphthasolone azium calonat corsone cortisumman decacort decaderm decadron A decalix decasone dekacort dekort delipos deltafluorene dergramin deronil desadrene desameton deseronil dexa-cortidelt dexa-mamallet dexa-scheroson dexa-sine dexacort dexacortal dexacortin dexadeltone dexafarma dexalona dexaltin dexameth dexamethasone alcohol dexamonozon dexapolcort dexapos dexaprol dexason dexasone dexinoral dexmethsone dexone dexonium dextelan dinomon diodex etacortilen fluormone fluorocort gammacorten gentalipos HL-dex hexadecadrol hexadrol isopto-dex lokalison F loverine luxazone MK-125 MK125 maxidex millicorten NSC-34521 NSC34521 oradexon pet-derm III posurdex prednisolon F prednisolone superprednol surodex visumetazone 23.483646408839
10012582 Diallyl Disulfide New 2179-57-9 ≥90% 2012-03-12 25.438090853284 diallyl-disulfide Garlicin; DADS; NSC 29228 disulphide dipropenyl H2S hydrogen sulfide cardiovascular diseases neuroscience vascular tone vasorelaxation neuroprotection cardiology hypertension signal transduction NSC29228 NSC-29228 garlic plants allicin 25.438090853284
10012577 Diallyl Trisulfide 2050-87-5 ≥98% 2009-04-07 13.105030536273 diallyl-trisulfide DATS; NSC 651936 garlic hydrogen sulfides H2S cancers tumors smooth muscle cholesterol atherosclerosis donors supresses colon synthesis genes expression adenocarcinomas HCT-15 cells PC-3 xenografts 13.105030536273
11095 DL-Palmitoylcarnitine chloride New 6865-14-1 ≥95% 2011-12-07 0.345029239766 dl-palmitoylcarnitine-chloride NSC 628323; Palmitoyl-DL-carnitine chloride carnitine acylcarnitine fatty acids oxidation mitochondria calcium tight junctions permeability cells calcium endothelial epithelial 6819-24-5 52234-80-7 68960-79-2 127719-10-2 carnitine palmitoyl intracellular extracellular oxidation energy mobilization junctions viability permeability resistance 0.345029239766
10008448 D-myo-Inositol-1,2,3,4-tetraphosphate (sodium salt) - ≥98% 2007-06-22 5.960257826887 d-myo-inositol-1-2-3-4-tetraphosphate-sodium-salt Ins(1,2,3,4)-P4 (sodium salt); 1,2,3,4-IP4 (sodium salt) phosphates IP3 transduction InsPs phosphatidylinositols phospholipases C Pleckstrin homology PH domains signalling signaling cells 5.960257826887
10008449 D-myo-Inositol-1,2,3,5-tetraphosphate (sodium salt) - ≥98% 2007-06-27 11.491201657459 d-myo-inositol-1-2-3-5-tetraphosphate-sodium-salt Ins(1,2,3,5)-P4 (sodium salt); 1,2,3,5-IP4 (sodium salt) inositols phosphates IP3 transduction InsP phosphatidylinositol phospholipase C Pleckstrin signaling signalling cells homology PH domains 11.491201657459
10008450 D-myo-Inositol-1,2,3,6-tetraphosphate (sodium salt) - ≥98% 2007-06-22 6.705290055248 d-myo-inositol-1-2-3-6-tetraphosphate-sodium-salt Ins(1,2,3,6)-P4 (sodium salt); 1,2,3,6-IP4 (sodium salt) inositols phosphates IP3 transduction InsP phosphatidylinositol phospholipases C Pleckstrin homology PH domains signalling signaling cells 6.705290055248
10008452 D-myo-Inositol-1,2,4,5,6-pentaphosphate (sodium salt) - ≥98% 2007-06-08 6.225796082370 d-myo-inositol-1-2-4-5-6-pentaphosphate-sodium-salt 1,2,4,5,6-IP5 (sodium salt); Ins(1,2,4,5,6)P5 (sodium salt) IP3 inositols phosphate transduction InsP phosphitidylinositol phospholipase C PLC InsP6 kinase signaling signalling cells 6.225796082370
10008451 D-myo-Inositol-1,2,4,5-tetraphosphate (sodium salt) - ≥98% 2007-06-22 9.098245856353 d-myo-inositol-1-2-4-5-tetraphosphate-sodium-salt 1,2,4,5-IP4 (sodium salt); Ins(1,2,4,5)P4 (sodium salt) phosphates IP3 transduction InsPs phosphatidylinositols phospholipases C Pleckstrin homology PH domains signalling signaling cells 9.098245856353
10008444 D-myo-Inositol-1,2,5,6-tetraphosphate (sodium salt) - ≥98% 2007-06-06 14.282983425414 d-myo-inositol-1-2-5-6-tetraphosphate-sodium-salt 1,2,5,6-IP4 (sodium salt); Ins(1,2,5,6)P4 (sodium salt) inositol phosphates IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC Grp-1 Pleckstrin homology PH domain signalling signaling cells 14.282983425414
10007780 D-myo-Inositol-1,2,6-triphosphate (sodium salt) - ≥98% 2006-01-13 9.701712707181 d-myo-inositol-1-2-6-triphosphate-sodium-salt 1,2,6-IP3; Ins(1,2,6)-P3 phosphates IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels D/L racemic Xenopus oocytes 9.701712707181
10007781 D-myo-Inositol-1,2-diphosphate (sodium salt) - ≥98% 2006-01-11 8.997292817679 d-myo-inositol-1-2-diphosphate-sodium-salt 1,3,5-IP3 (sodium salt); Ins(1,3,5)P3 (sodium salt) phosphates IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels meso compounds Xenopus oocytes 8.997292817679
10008439 D-myo-Inositol-1,2-diphosphate (sodium salt) 208584-51-4 ≥98% 2008-01-17 9.703133385951 d-myo-inositol-1-2-diphosphate-sodium-salt 1,2-IP2 (sodium salt); Ins(1,2)P2 (sodium salt) inositols phosphates IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC signaling signalling PtdIns initiating Ca2+ calcium release phosphoinositols 9.703133385951
10009851 D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) - >98% 2007-06-04 6.835635359115 d-myo-inositol-1-3-4-5-6-pentaphosphate-ammonium-salt 1,3,4,5,6-IP5 (sodium salt); Ins(1,3,4,5,6)P5 inositols phosphate IP5 signal transduction InsP phosphitidylinositol phospholipase C PLC phosphioinositide 3-kinase PI3-K Akt cancer angiogenesis PKB protein kinase B 6.835635359115
10007784 D-myo-Inositol-1,3,4,5,6-pentaphosphate (sodium salt) - ≥98% 2006-01-13 9.804646699621 d-myo-inositol-1-3-4-5-6-pentaphosphate-sodium-salt 1,3,4,5,6-IP5 (sodium salt); Ins(1,3,4,5,6)P5 (sodium salt) phosphoinositides 3-kinases PI3-K/Akt phosphates IP3 signals transductions cells growh proliferation anticancers agents isomers InsP phosphitidylinositols phospholipases messengers cellular PKB apoptosis ovarian lung breast antiangiogenic in vitro capillary tubes HUVEC antitumor xenografts nude mice PH domains Grp1 9.804646699621
60980 D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt) 210488-61-2 ≥98% 21.776631739379 d-myo-inositol-1-3-4-5-tetraphosphate-sodium-salt Ins(1,3,4,5)-P4; 1,3,4,5-IP4 IP4 inositols tetraphosphates salts phosphorylation 1,4,5-triphosphate-3-kinase intracellular calcium InsPs 21.776631739379
10008442 D-myo-Inositol-1,3,4,6-tetraphosphate (ammonium salt) 142507-74-2 ≥95% 2008-12-04 11.019539594843 d-myo-inositol-1-3-4-6-tetraphosphate-ammonium-salt 1,3,4,6-IP4; Ins(1,3,4,6)-P4 inositol myo-inositol inositol phosphate second messenger inositol-1,2,3,4,5,6-hexakisphosphate phytic acid signal transduction 11.019539594843
10008443 D-myo-Inositol-1,3-diphosphate (sodium salt) 208584-52-5 ≥98% 2006-12-21 12.152804679883 d-myo-inositol-1-3-diphosphate-sodium-salt Ins(1,3)-P2 (sodium salt); 1,3-IP2 (sodium salt) phosphates IP2 signals transductions InsP phosphatidyls inositols messengers cellular phospholipases PLC ER endoplasmic reticulum calcium Ca2+ dephosphorylation 12.152804679883
10007783 D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt) - ≥98% 2006-01-13 18.516368658965 d-myo-inositol-1-4-5-6-tetraphosphate-sodium-salt 1,4,5,6-IP4; Ins(1,4,5,6)-P4 oligophosphates isomers IP3 signals transductions InsP phosphatidylinositols phospholipases intestinal epithelial cells strains incubation times Salmonella epidermal growth factor EGF PI3-kinases cellular calcium Ca2+ Ca++ channels D/L racemic mixture Xenopus oocytes 18.516368658965
60960 D-myo-Inositol-1,4,5-triphosphate (potassium salt) 103476-24-0 ≥98% 25.118868426437 d-myo-inositol-1-4-5-triphosphate-potassium-salt Ins(1,4,5)-P3 (potassium salt); 1,4,5-IP3 (potassium salt) IP3 inositols triphosphates salts phosphorylation receptors messengers inositol-4,5-biphosphate hydrolysis intracellular calcium PLC phospholipases InsPs 25.118868426437
10008205 D-myo-Inositol-1,4,5-triphosphate (sodium salt) - ≥98% 2006-01-30 12.640227494312 d-myo-inositol-1-4-5-triphosphate-sodium-salt 1,4,5-IP3 (sodium salt); Ins(1,4,5)P3 (sodium salt) phosphates IP3 signals transductions InsP phosphitidylinositols Ins(1,4,5)P3 phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels analogs agonists rat hepatic receptors 12.640227494312
10008438 D-myo-Inositol-1,4-diphosphate (sodium salt) - ≥98% 2007-01-08 11.094319142021 d-myo-inositol-1-4-diphosphate-sodium-salt 1,4-IP2 (sodium salt); Ins(1,4)-P2 (sodium salt) phosphates IP2 signals transductions InsP phosphatidyls inositols messengers cellular phospholipases PLC ER endoplasmic reticulum calcium Ca2+ dephosphorylation signalling 11.094319142021
10008422 D-myo-Inositol-1,5,6-triphosphate (sodium salt) 120965-76-6 ≥98% 2009-08-04 24.697269797421 d-myo-inositol-1-5-6-triphosphate-sodium-salt Ins(1,5,6)-P3 (sodium salt); 1,5,6-IP3 (sodium salt) phosphates IP2 signal transduction cells cycling apoptosis differentiation motility InsP phosphatidyl inositol IP3 second messengers trisphosphates PtdIns phosphatidylinositol D-myos PIPS 24.697269797421
10008441 D-myo-Inositol-1,5-diphosphate (sodium salt) - ≥98% 2007-06-13 10.530092081030 d-myo-inositol-1-5-diphosphate-sodium-salt 1,5-IP2 (sodium salt); Ins(1,5)-P2 (sodium salt) inositol phosphates IP3 signaling transduction signalling cells InsP phosphitidylinositols phospholipases cPLC 10.530092081030
10007777 D-myo-Inositol-1-phosphate (sodium salt) - ≥98% 2006-01-13 11.571459213519 d-myo-inositol-1-phosphate-sodium-salt Ins(1)P1 (sodium salt); 1-IP1 (sodium salt) phosphates IP1 signals transductions InsP phosphatidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels meso compounds Xenopus oocytes 11.571459213519
10008456 D-myo-Inositol-2,3,4,5-tetraphosphate (ammonium salt) - ≥98% 2007-06-25 7.472670349908 d-myo-inositol-2-3-4-5-tetraphosphate-ammonium-salt 2,3,4,5-IP4 (ammonium salt); Ins(2,3,45)-P4 (ammonium salt) inositol phosphates IP3 signals transduction InsP phosphitidylinositols phospholipases cPLC signaling signalling 7.472670349908
10008423 D-myo-Inositol-2,3,5-triphosphate (ammonium salt) - ≥98% 2008-09-30 8.720417434008 d-myo-inositol-2-3-5-triphosphate-ammonium-salt Ins(2,3,5)P3 (ammonium salt); 2,3,5-IP3 (ammonium salt) phosphates IP3 signal transduction InsP phosphitidylinositols phospholipase C PLC cell signaling calcium channels 8.720417434008
10007779 D-myo-Inositol-2,4,5-triphosphate (sodium salt) - ≥98% 2006-01-13 10.853308778391 d-myo-inositol-2-4-5-triphosphate-sodium-salt 2,4,5-IP3 (sodium salt); Ins(2,4,5)P3 (sodium salt) phosphates IP3 signals transductions InsP phosphitidylinositols Ins(1,4,5)P3 phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels analogs agonists rat hepatic receptors 10.853308778391
10008419 D-myo-Inositol-2,4-diphosphate (sodium salt) - ≥98% 2009-08-04 26.105584714548 d-myo-inositol-2-4-diphosphate-sodium-salt Ins(2,4)-P2 (sodium salt); 2,4-IP2 (sodium salt) phosphates IP2 signals transduction cells cycling apoptosis differentiation motility InsP phosphatidyl inositols IP3 second messengers biphosphates bisphosphates PtsIns phosphatidylinositol 106358-02-5 26.105584714548
10008424 D-myo-Inositol-2,5,6-triphosphate (sodium salt) - ≥98% 2008-10-10 5.193100061387 d-myo-inositol-2-5-6-triphosphate-sodium-salt Ins(2,5,6)P3 (sodium salt); 2,5,6-IP3 (sodium salt) phosphates IP3 signal transduction InsP phosphitidylinositols phospholipase C PLC cell signaling calcium channels L-myo-Inositol-2,4,5-triphosphate (sodium salt) 5.193100061387
10007782 D-myo-Inositol-3,4,5,6-tetraphosphate (sodium salt) - ≥98% 2006-01-13 17.501175288799 d-myo-inositol-3-4-5-6-tetraphosphate-sodium-salt 3,4,5,6-IP4; Ins(3,4,5,6)-P4 oligophosphates isomers kinases IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels Xenopus oocytes 17.501175288799
10008425 D-myo-Inositol-3,4,5-triphosphate (sodium salt) - ≥98% 2007-06-05 4.438293431553 d-myo-inositol-3-4-5-triphosphate-sodium-salt 3,4,5-IP4; Ins(3,4,5)-P3 inositols phosphate IP3 signal transduction InsP phosphitidylinositol phospholipase C PLC 4.438293431553
10007778 D-myo-Inositol-3-phosphate (sodium salt) - ≥98% 2006-01-13 10.758199545011 d-myo-inositol-3-phosphate-sodium-salt Ins(3)P1 (sodium salt); 3-IP1 (sodium salt) phosphates IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels dephosphorylation 10.758199545011
10008418 D-myo-Inositol-4,5-diphosphate (sodium salt) - ≥98% 2007-01-04 9.953259668507 d-myo-inositol-4-5-diphosphate-sodium-salt Ins(4,5)-P2 (sodium salt); 4,5-IP2 (sodium salt) IP3 myo-inositols Ins(1,4,5)P3 Ins(4,5)P2 cells signaling transduction diphosphates salts InsPs phosphorylation receptors messengers inositol-4,5-biphosphate hydrolysis intracellular calcium PLC phospholipases signalling 9.953259668507
10008437 D-myo-Inositol-4-phosphate (ammonium salt) 142760-33-6 ≥98% 2006-10-18 8.482741712706 d-myo-inositol-4-phosphate-ammonium-salt 4-IP1 (ammonium salt); Ins(4)P1 (ammonium salt) phosphates IP4 signals transductions InsP phosphatidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels dephosphorylation polyphosphates monophosphatase PtdIns 8.482741712706
9000639 Docosahexaenoyl Serotonin Exclusive 283601-58-1 ≥98% ✓ 2010-05-18 6.647182320442 docosahexaenoyl-serotonin N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA L-alpha-Glycerylphosphorylcholine L alpha Glycerylphosphorylcholine Glycerophospholipids Choline Choline Glycerophospholipids Phosphoglycerides Choline 3-Phosphocholine Glycerol Glycerylphosphorylcholine Glycerophosphate Choline Glycerol 3-Phosphocholine Glycerol 3 Phosphocholine Choline Phosphoglycerides Glycerophosphorylcholine Choline Glycerophosphate Alphoscerate Choline Phosphatidylcholines Choline Alphoscerate Alfoscerate Choline Phosphatidylcholine Choline Alfoscerate 6.647182320442
10460 Doramapimod 285983-48-4 ≥98% 2011-06-02 19.724613259668 doramapimod BIRB-796 p38 MAPKs inflammation TNFα TNF-α TNF α TNFalpha TNF-alpha TNF alpha JNKs inhibitors proteins kinases tumors necrosis factors LPS THP.1 cells THP1 BIRB796 BIRB 796 mitogen activated mitogen-activated proinflammatory cytokins interleukin-1 IL IL-1 interleukin 1 19.724613259668
13352 EHNA (hydrochloride) 58337-38-5 ≥98% 2011-10-07 766.115469613259 ehna-hydrochloride 51350-19-7 79763-32-9 59262-86-1 ADA reversible adenosine deaminase inhibitors inhibits inhibition cGMP PDE2 potent PDE1 PDE3 PDE4 phosphodiesterase ardioprotective ischemia stem cells 766.115469613259
10964 Eicosapentaenoyl Ethanolamide 109001-03-8 ≥98% 2011-06-22 57.375516969219 eicosapentaenoyl-ethanolamide EPEA cannabinoids CBSs endocannabinoids forensic sciences signals signaling N-acylethanolamide N-acylethanolamine NAE dietary restrictions lifespans TOR nematodes eicosapentaenoic acids inflammation anti-inflammatory 57.375516969219
9000640 Eicosapentaenoyl Serotonin Exclusive 199875-71-3 ≥98% ✓ 2010-09-10 2.566314127861 eicosapentaenoyl-serotonin N-arachidonoyl serotonins AA-5-HT AA5HT AA 5 HT AA-5HT AA5HT antagonists fatty acids Amide hydrolase FAAH transient receptors potential vanilloid type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA Triacylglycerols Triacylglycerol Triglycerides 2.566314127861
10010238 Erbstatin Analog 63177-57-1 ≥98% 2008-06-06 0.437569060774 erbstatin-analog Methyl 2,5-dihydoxycinnamate analogs EGF EGFR inhibitors inhibits inhibition tyrosine kinase DNA synthesis cell cycle proliferation cancers 0.437569060774
10483 Erlotinib 183321-74-6 ≥98% 2010-08-11 27.513535911602 erlotinib Tarceva™; CP 358,774; NSC 718781 tyrosine kinase inhibitor inhibits inhibiting epidermal growth factor receptors EGFR cancers tumor cyclin-dependent cyclin dependent kinase 2 CDK-2 CDK 2 CDK2 JAK-2 JAK2 JAK JAK2V617F CP-358,774 CP-358774 CP 358774 CP358774 CP358,774 NSC-718781 NSC718781 OSI-744 OSI744 R-1415 R1415 R 1415 OSI 744 Quinazolines 27.513535911602
10010501 Farnesyl Thiosalicylic Acid 162520-00-5 ≥96% 2008-06-02 18.336316758748 farnesyl-thiosalicylic-acid Salirasib; FTS ras inhibitors inhibition inhibits cancer anti-cancer anticancer prenylation farnesylation signal transduction oncogene atherosclerosis farnesylthiosalicylic acid 18.336316758748
13175 Farnesyl Thiosalicylic Acid Amide Exclusive 1092521-74-8 ≥96% ✓ 2009-02-26 17.489226519336 farnesyl-thiosalicylic-acid-amide Salirasib Amide; FTS Amide Ras degradation cells signaling signalling tumors glioblastoma cancers inhibitors inhibits inhibition 17.489226519336
13179 FKGK 11 1071000-98-0 ≥98% 2009-06-30 21.816983425414 fkgk-11 Phospholipases A2 iPLA2 inhibitors signal transduction inhibition PLAs 21.816983425414
11018 Forskolin New 66575-29-9 ≥98% 2012-01-03 264.475990638429 forskolin NSC 357088; HL 362; NSC 375489; L 75-1362B; Coleonol colforsin forslean HL 362 HL362 HL-362 L 75-1362B L75-1362B L-75-1362B NSC 357088 NSC357088 NSC-357088 NSC 375489 NSC375489 NSC-375489 cAMP signaling adenylyl cyclase diterpene Indian Coleus plants cyclic AMP cells tissues ATP transporters ions channels expressions regulations G proteins G-proteins 64657-11-0 264.475990638429
13166 Gefitinib 184475-35-2 ≥98% 2010-02-11 21.037874382088 gefitinib Iressa™; ZD1839 EGFR-TK EGFRs TKs epidermal growth factors inhibitors cancers signal transduction tyrosine kinases inhibits inhibited NSCLC Quinazolinones 21.037874382088
13355 Geldanamycin 30562-34-6 ≥98% 2010-07-29 35.265105447297 geldanamycin NSC 122750 NSC 212518 antibiotics heat shock proteins 90 Hsp90 GRP94 gp96 genes expression cells proliferation apoptosis angiogenesis c-jun adenocarcinoma cancers AP-1 steroids receptors 2,5-Cyclohexadiene-1,4-Diones 1,4-Benzoquinones 1,2-Benzoquinones p-Benzoquinones-o-Benzoquinones Benzoquinones Benzodiones Quinones geldanomycin GDM NSC122750 NSC-122750 NSC 122750 AC-6794 BRN 1633093 geldanamicin 30562-34-6 antibiotic U29135 U-29135 U 29135 AC1NQZ81 ligands GRP94 Hsp 90 35.265105447297
11569 GSK 1059615 New 958852-01-2 ≥98% 2012-03-15 30.959325890116 gsk-1059615 Phosphatidylinositols PI 3-kinases α PI3Ks PI3Kα PI3Ka PI3K.alpha. inhibits inhibitors inhibition thiazolidinediones cells growth human cancers ATP-competitive p110α p110.alpha. p110a E542K E545K H1047R BT474 tumors xenografts MAPKs signaling biology signals transductions 30.959325890116
13127 GW 4869 6823-69-4 ≥90% 2009-06-10 53.862989564150 gw-4869 inhibitors sphingomyelin sphingomyelinase neutral acidic TNF-α ceramides cells death GW4869 gw-4869 53.862989564150
13345 GYY 4137 Exclusive 106740-09-4 ≥95% ✓ 2009-07-31 73.799575541861 gyy-4137 hydrogen sulfides H2S gaseous mediators nitric oxides NOs donors vasodilator antihypertensive anti-hypertensive rats spontaneously hypertensive hypertension models endotoxic shock TNF-α TNFα TNF α TNF-a TNFa IL-1b IL1b IL-1β IL1β IL-6 IL6 NFkB NF-kB NF-κB NFκB iNOS COX-2 COX2 PGE2 110-91-8 106740-08-3 73.799575541861
10010556 H-89 127243-85-0 ≥98% 2008-07-08 25.158066298343 h-89 5-Isoquinolinesulfonamide; Protein Kinase Inhibitor H-89 inhibitors inhibits inhibition PKA cAMP cell signaling protein kinase S6K1 MSK1 ROCK-II ROCKII PKB.alpha. PKBalpha PKBa MAPKAP-K1b MAPKAPK1b H89 H 89 25.158066298343
10010249 H-8 (hydrochloride) 113276-94-1 ≥98% 2008-07-17 13.932707182321 h-8-hydrochloride Protein Kinase Inhibitor H-8 PKA PKG PKC MLCK cyclin C CDK8 cyclin H CDK7 p36 signal transduction inhibitor inhibits inhibition transcription 84478-11-5 13.932707182321
13312 H-9 (hydrochloride) - ≥98% 2009-07-14 12.977541436464 h-9-hydrochloride Protein Kinase Inhibitor H-9 proteins kinases inhibitors inhibits inhibitions PKCs PKAs PKGs cGMPs cAMPs signal transductions competitive potent PKA-mediated mediated phosphorylation 84468-17-7 12.977541436464
13205 Halopemide Exclusive 59831-65-1 ≥98% ✓ 2009-04-21 9.318287292817 halopemide R34301; NSC 354856 inhibitors phospholipases D PLD PLD1 PLD2 dopamine receptors inhibits inhibition potent cells DP nueraleptic 9.318287292817
13347 IBMX 28822-58-4 ≥98% 2009-10-27 521.527108655617 ibmx NSC 165960; 1-Methyl-3-Isobutylxanthine; Isobutylmethylxanthine inhibitor cAMP cGMP phophodiesterases PDE1 PDE2 PDE3 PDE4 PDE5 PDE7 PDE11 PDE8A PDE8B PDE9 cyclic-nucleotides methylxanthines caffeine theophylline adenosine receptors antagonist SC 2964 SC-2964 SC2964 IMX NSC165960 NSC-165960 xanthine 521.527108655617
13624 Icariin 489-32-7 ≥97% 2010-02-11 1.115469613259 icariin PDE5 inhibitors flavonoids differentiation cancers proliferation flavonols E brevicornum horny goat weed BMP2 ED erectile dysfunction 2-Phenyl-Benzopyrans 2 Phenyl Benzopyrans 2-Phenyl-Chromenes 2 Phenyl Chromenes Bioflavonoids Flavonoids 1.115469613259
13314 Indirubin-3'-monoxime 160807-49-8 ≥98% 2009-07-15 15.600626151012 indirubin-3-monoxime glycogen synthase kinase-3β GSK-3β tau proteins Alzheimer's diseases cyclin-dependent kinases CDK CDK1 cyclin A B E D1 CDK4 CDK2 CDK5 p35 growth proliferation synchronization cells arrest G2/M phases phosphorylation inhibits inhibition inhibitors 15.600626151012
10004974 Ionomycin 56092-81-0 ≥98% 2011-09-30 18.423959484346 ionomycin ionophores calcium transport streptomyces conglobatus intracellular cytokines membranes stores biological SQ23377 SQ-23377 SQ 23377 D10.251.355.391 18.423959484346
13843 IRAK-1 Polyclonal Antibody - 2010-11-11 0.866298342541 irak-1-polyclonal-antibody Interleukin-1 Receptor-Associated Kinase 1 NF-kB NF-κB NFkB NFκB NF kB NFκB NF-kappaB kappaB NFkappaB NF.kappa.B NF-.kappa.B .kappa.B nuclear factor κB serine threonine serine/threonine IL-1 IL1 IL 1 receptors signaling cascase activation members novel cytokines IL-18 IL18 18 IGIF antibodies western blots blotting immunoblotting WB IP immunoprecipatation IRAK-1 0.866298342541
13288 Itraconazole 84625-61-6 ≥95% 2011-02-22 26.258240868630 itraconazole hedgehogs signaling cancer antifungal inverse agonist patched smoothened Canditral Cladosal 100 Itralek Itrizole Oriconazole Orungal R 51211 Sempera Spherazole CR IR Sporal Sporamelt Sporanox Sporonox Traconal Triasporin Janssen-Cilag Brand of Itraconazole Janssen Cilag Brand of Itraconazole Janssen Brand of Itraconazole Itraconazole Janssen Brand Itraconazole Sporanox R-51211 R 51211 Orungal R51211 26.258240868630
13659 IWR-1-endo 1127442-82-3 ≥98% 2010-03-23 21.186758747697 iwr-1-endo Wnt cancers embryonic developments tissues homeostasis embryogenesis tumorigenesis stem cells β-catenin genes expression transcription inhibitors inhibits inhibition proteasomes Apc Axin2 Ck1 Gsk3β IWR-1-exoendo-1,3(4)-beta-D-glucanase Endo-1,3(4)-beta-Glucanase Endo-1,3(4)-B-Glucanase beta-(1-3,1-4)glucanase 21.186758747697
13598 IWR-1-exo 1127442-87-8 ≥98% 2010-03-23 16.155635359116 iwr-1-exo Wnt cancers embryonic developments tissues homeostasis embryogenesis tumorigenesis stem cells β-catenin genes expressio Cellobiohydrolase, 1,4-beta-D-Glucan 1,4-beta-D-Glucan Cellobiohydrolase 1,4 beta D Glucan Cellobiohydrolase 1,4-beta-Cellobiosidase, Cellulose Cellulose 1,4-beta-Cellobiosidase Cellulose 1,4 beta Cellobiosidase Beta-Glucancellobiohydrolase Beta Glucancellobiohydrolase Exo-Cellobiohydrolase Exo Cellobiohydrolase Cellobiohydrolase II Cellobiohydrolase I Cellobiohydrolase A Cellobiohydrolase Exoglucanase II CEL1 Protein CbhI Proteinn transcription inhibitors inhibits inhibition controls 16.155635359116
13924 IκBα (Phospho-Ser32/36) Monoclonal Antibody - biotin (Clone 39A1413) - 2010-09-29 0E-12 i-b-phospho-ser32-36-monoclonal-antibody-biotin-clone-39a1413 antibodies IκBα IkBa IκBa IkBα IκB-α IκB α intracellular NF-κB NFκB NF κB slienced slience inhibitory inhibits inhibition inhibitor proteins asutoregulated auto-regulated auto regulated regulates phosphorylated kinase complex IKK IKK1 IKK2 IKK3 IKK-1 IKK-2 IKK-3 1 2 3 IKK1/a IKK1-a IKK1a IKK2/b IKK2-b IKK2b IKK3/g IKK3-g IKK3g degradation phosphorylation dimers translocates nucleus genes target serines serine32 serine36 serine-32 serine-36 32 36 ser32 ser36 ser-32 ser-36 ser EIA ELISA biotins biotinylated inflammation genes regulation signal transduction 0E-12
13923 IκBα (Phospho-Ser32/36) Monoclonal Antibody (Clone 39A1413) - 2010-09-29 12.893068809643 i-b-phospho-ser32-36-monoclonal-antibody-clone-39a1413 antibodies IκBα IkBa IκBa IkBα IκB-α IκB α intracellular western blots blotting immunoblotting WB NF-κB NFκB NF κB slienced slience inhibitory inhibits inhibition inhibitor proteins asutoregulated auto-regulated auto regulated regulates phosphorylated kinase complex IKK IKK1 IKK2 IKK3 IKK-1 IKK-2 IKK-3 1 2 3 IKK1/a IKK1-a IKK1a IKK2/b IKK2-b IKK2b IKK3/g IKK3-g IKK3g degradation phosphorylation dimers translocates nucleus genes target immunoprecipitation IP serines serine32 serine36 serine-32 serine-36 32 36 ser32 ser36 ser-32 ser-36 ser genes regulation inflammation signal transduction 12.893068809643
13921 IκBα Polyclonal Antibody - 2010-09-23 0E-12 i-b-polyclonal-antibody antibodies IκBα IkBa IκBa IkBα IκB-α IκB α intracellular western blots blotting immunoblotting WB NF-κB NFκB NF κB slienced slience inhibitory inhibits inhibition inhibitor proteins asutoregulated auto-regulated auto regulated regulates phosphorylated kinase complex IKK IKK1 IKK2 IKK3 IKK-1 IKK-2 IKK-3 1 2 3 IKK1/a IKK1-a IKK1a IKK2/b IKK2-b IKK2b IKK3/g IKK3-g IKK3g degradation phosphorylation dimers translocates nucleus genes target 0E-12
10011246 Janex 1 202475-60-3 ≥98% 2008-12-17 0.861878453039 janex-1 WHI-P131 inhibitors inhibits inhibition JAK3 apoptosis leukemias anti-inflammatory antiinflammatory lymphocytes WHIP131 Janex 1 0.861878453039
10008131 JNJ-10198409 627512-69-0 ≥98% 2006-10-18 16.361977900553 jnj-10198409 PDGF-BB tyrosine kinases inhibits inhibition inhibitors growth factors receptors platelet-derived antiangiogenic antiproliferative coronary artery smooth muscle cells antagonists ATP binding hydrolysis tumors angiogenesis 16.361977900553
11511 JNK2 Polyclonal Antibody - 2011-11-18 0E-12 jnk2-polyclonal-antibody SAPK1a; p54a; c-Jun Amino Terminal Kinase 2; MAPK9 antibody c-Jun kinases JNKs MAP phosphorylation JNK1 JNK3 nuclear signals transduction proteins transcription factors p53 Western blots WB blotting JNKs JNK-1 JNK-2 JNK-3 0E-12
10009458 JTE-013 383150-41-2 ≥98% 2007-01-18 70.191724984653 jte-013 reverses inhibition inhibits coronary artery smooth muscles lipids cells proliferation cytoskeletal morphogenesis GPCRs protein-coupled receptors antagonists S1P2 humans rats EDG5 sphingosines sphingosine-1-phosphates sphingosine1 inhibitors JTE013 FDG-5 cancers 70.191724984653
10010239 Kenpaullone 142273-20-9 ≥98% 2007-09-04 13.485745856354 kenpaullone NSC 664704; 9-Bromopaullone GSK-3.beta. cyclin-dependent kinase cyclin CDK inhibitors inhibits inhibition proliferations cell cycle cancers 13.485745856354
13243 KH7 330676-02-3 ≥98% 2009-09-18 146.562790055248 kh7 sAC soluble adenylyl cyclase cAMP inhibitors inhibits inhibition cells signaling signal transduction second messenger KH 7 KH-7 signalling cyclic AMP 146.562790055248
13318 KN-62 127191-97-3 ≥98% 2009-07-16 19.261723756906 kn-62 inhibitors calcium calmodulin-dependent kinase II CaM kinase II purinergic receptors P2RX7 P2X7 inhibition inhibited selective permeableCaMKII calcium ca modulation CaMK11CaMK2 19.261723756906
9000890 KN-92 (hydrochloride) - ≥98% 2011-05-25 21.694033149172 kn-92-hydrochloride Ca2+/calmodulin-dependents kinases II CaMKII KN-93 controls cells cycles inhibitors inhibited inhibition NIH 3T3 13319 inhibits KN92 KN 92 KN93 KN 93 21.694033149172
13319 KN-93 139298-40-1 ≥98% 2009-08-05 28.510515653776 kn-93 inhibitors inhibits inhibition Ca2+ calmodulin dependent Ca2+/calmodulin-dependent kinase II CaMKII histamine parietal cells cardiac myocytes 5-LO 5-lipoxygenase HIF-1a HIF-1α HIF1α colon cancers phosphorylation CAM 28.510515653776
10011011 KT 5720 108068-98-0 ≥98% 2009-01-20 131.231846882399 kt-5720 PKAs cAMPs signaling proteins kinase inhibitors inhibits inhibition phosphorylase kinase PDK1 MEK MSK1 PKα GSK3β KT5720 KT-5720 131.231846882399
10010965 KT 5823 126643-37-6 ≥95% 2009-01-15 145.532937384898 kt-5823 cGMP PKGs proteins kinases G inhibitors inhibits inhibition nitric oxides NO antibiotic KT5823 KT-5823 indolocarbazoles alkaloid PKG 145.532937384898
10011565 L-161,982 147776-06-5 ≥98% 2009-02-26 47.734990791896 l-161-982 PGEs PGE2 EPs EP4 receptors antagonist bone formation inflammation cells proliferation colon cancers L161982 L-161982 47.734990791896
10010631 Latrunculin B 76343-94-7 ≥97% 2009-02-20 16.449338779828 latrunculin-b monomeric actins G-actin G actins F-actin F inhibitors inhibits inhibition cytoskeleton 16.449338779828
10010329 Lavendustin C 125697-93-0 ≥98% 2008-07-08 11.503353591160 lavendustin-c HDBA; NSC 666251 EGFR kinases tyrosine pp60c-src pp60csrc CamKII SOD neutrophil activation erbstatin inhibitor inhibits inhibition Lavendustin-C 11.503353591160
10008426 L-myo-Inositol-1,4,5-triphosphate (sodium salt) 2068-89-5 ≥98% 2009-09-14 5.007632202052 l-myo-inositol-1-4-5-triphosphate-sodium-salt 1,4,5-IP3 (sodium salt); Ins(1,4,5)P3 (sodium salt); D-myo-Inositol-3,5,6-triphosphate (sodium salt) inositols phosphates calcium cells signaling isomers D-myo-inositol-1,4,5-triphosphate 2068-89-5 5.007632202052
10010497 Manumycin A 52665-74-4 ≥98% 2008-06-25 16.571464088398 manumycin-a UCF 1C; NSC 622141 farnesyltransferase inhibitors inhibits inhibition cancer antitumor anti-tumor signal transduction Ras farnesylation NF-.kappa.B NF-kB NF-kappaB 16.571464088398
13846 MEK1/2 Polyclonal Antibody - 2010-11-17 0E-12 mek1-2-polyclonal-antibody MAP Kinase Kinase 1/2 MEK-1/2 MEK1/2 MEK1 MEK2 MEK-1 MEK-2 MEK 1 2 kinases MAP MAPK cascade cells growth differentiation synaptic plastic plasticity brain phosphorylation serines Ser218 Ser222 Ser-218 Ser-222 Sers 218 222 theronine tyrosine ERK western blotting blots immunoblotting WB antibodies affinity pruified 0E-12
10009518 MEK1 (Phospho-Thr292) Polyclonal Antibody - 2007-01-12 0E-12 mek1-phospho-thr292-polyclonal-antibody MAP Kinase Kinase 1; MAPKK1 antibodies WB western blot MEK 1 phosphorylation MAP kinase cell growth differentiation threonine tyrosine phospho-specific blotting immunoblotting 0E-12
10009517 MEK1 (Phospho-Thr386) Polyclonal Antibody - 2007-01-11 0E-12 mek1-phospho-thr386-polyclonal-antibody MAPK1; MAP Kinase Kinase 1 antibodies WB western blot MEK 1 phosphorylation MAP kinase cell growth differentiation threonine tyrosine phospho-specific blotting immunoblotting 0E-12
13848 MEKK2 Polyclonal Antibody - 2010-12-21 0E-12 mekk2-polyclonal-antibody MAP Kinase/ERK Kinase Kinase 2; Dual Specificity MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinase 2; MAP3K2; MAPKKK2 MEKs MEK-2 MEK 2 MAPKs kinases MAPs mitogen-activated mitogen activated proteins signaling pathway phosphorylate IkB I.kappa.B IkappaB IκB NF-κB NF-kappaB NF-.kappa.B NFκB NF.kappa.B NFkB T-cells T cells cytokine genes expressions mast cells epidermal growth factor EGRs fibroblast growth factor-2 factor 2 FGF-2 FGF2 FGFs 2 signals rheumatoid arthritis LPS-TLR4 LPS TLR4 TLR-4 TLR 4 ligands phosphorylation western blots blotting immunoblotting WB immunohistochemistry IHC MAP kinase kinase kinase 0E-12
10010236 ML-9 105637-50-1 ≥98% 2008-01-21 13.940220994475 ml-9 PKB Akt inhibitors inhibits inhibition serine/threonine kinase PKA P90S6 MAP kinases cancers anti-cancers insulin glucose transports calcium channels calmodulin intracellular smooth muscles asthma 13.940220994475
10230 (+)-Muscarine (iodide salt) 24570-49-8 ≥95% 2010-05-06 0.801602209944 -muscarine-iodide-salt neurochemistry 300-54-9 2438-77-9 poisonous mushroom acetylcholine G proteins Alzheimer's disease signal transduction L-muscarine Amanita muscaria 0.801602209944
13746 MyD88 Polyclonal Antibody - 2010-02-05 29.845635359116 myd88-polyclonal-antibody proteins antibodies western blots blotting immunoblotting WB interleukin-1 interleukins 1 IL-1 ILs signaling N-terminal NF-κB NFκB NF κB death domain signalling 29.845635359116
9001147 N-3-hydroxydecanoyl-L-Homoserine lactone Exclusive New 192883-12-8 ≥98% ✓ 2012-04-19 77.182554235372 n-3-hydroxydecanoyl-l-homoserine-lactone OH-C10-HSL bacteria quorum sensing genes regulations infections signal transductions HSLs HL lactones OHC10HL cells growth molecules 77.182554235372
9001150 N-3-hydroxyoctanoyl-L-Homoserine lactone Exclusive New 192883-14-0 ≥98% ✓ 2012-04-19 77.605403837539 n-3-hydroxyoctanoyl-l-homoserine-lactone OH-C8-HSL bacteria quorum sensing genes regulations infections signals transductions lactones HSL HL cells growth molecules OHC8HL 77.605403837539
13063 N-3-oxo-tetradecanoyl-L-Homoserine lactone Exclusive 177158-19-9 ≥98% ✓ 2009-01-29 21.390107239333 n-3-oxo-tetradecanoyl-l-homoserine-lactone N-3-oxo-myristoyl-L-Homoserine lactone; 3-oxo-C14-HSL quorum sensing bacteria biofilm gene expressions growth putisolvin lactones HSLs 21.390107239333
13136 N-acetyl-D-Glucosamine 7512-17-6 ≥98% 2009-03-13 84.386666666667 n-acetyl-d-glucosamine Marine Sweet; GlcNAc; NSC 524344; NAG monosaccharide glucose O-GlcNAc alzheimer's disease genes expressions chitin cells signalling signaling post-translational modification signal transduction 84.386666666667
10011060 N-acetyl-D-Mannosamine 7772-94-3 ≥95% 2008-11-11 0.375138121547 n-acetyl-d-mannosamine ManNAc acids sialylation proteinuria glomerular diseases neuromuscular disorders HIBM sialic 0.375138121547
10011203 N-dodecanoyl-L-Homoserine lactone Exclusive 137173-46-7 ≥98% ✓ 2009-01-06 9.824895288935 n-dodecanoyl-l-homoserine-lactone C12-HSL; dDHL quorum sensing bacteria biofilm gene expressions NF-kb NFkb macrophage keratinocyte C12-Homoserine Lactone 9.824895288935
9000710 N-dodecanoyl-L-Homoserine lactone-3-hydrazone-biotin Exclusive - ≥95% ✓ 2011-01-17 32.394512169628 n-dodecanoyl-l-homoserine-lactone-3-hydrazone-biotin N-dodecanoyl-L-HSL-3-hydrazone-biotin quorum sensing proteolysis affinity probes avidin lactones HSLS biotinamide biotinimide biotins 32.394512169628
13755 NF-κB (p50) Monoclonal Antibody (Clone 2J10D7) - 2010-02-05 12.341988950276 nf-b-p50-monoclonal-antibody-clone-2j10d7 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB nuclear transcription factors cytokines UV radiations stress injury bacterial viral cells growth differentiation proliferation apoptosis inflammation DNA AIDS cancers arthritis western blots blotting immunoblotting IHC WB immunohistochemistry 12.341988950276
13754 NF-κB (p50) Polyclonal Antibody - 2010-04-27 11.631353591160 nf-b-p50-polyclonal-antibody NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB nuclear transcription factors DNA p65 N-terminal binding western blots blotting immunoblotting WB antibodies 11.631353591160
13756 NF-κB (p65) Monoclonal Antibody-biotin (Clone 112A1021) - 2010-02-11 20.124822415153 nf-b-p65-monoclonal-antibody-biotin-clone-112a1021 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting WB biotins biotinylated biontinylation 112A1021 clones 20.124822415153
13752 NF-κB (p65) Monoclonal Antibody (Clone 112A1021) - 2010-02-11 20.313535911601 nf-b-p65-monoclonal-antibody-clone-112a1021 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting flow cytometry FC WB immunohistochemistry IHC 20.313535911601
13751 NF-κB (p65) NLS Polyclonal Antibody - 2010-02-11 20.545580110496 nf-b-p65-nls-polyclonal-antibody Nuclear Factor-κB (p65) Nuclear Localization Signal NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB transcription factors N-terminal C-terminal terminals terminus signals tissues nuclear receptors western blots blotting immunoblotting WB immunocytochemistry ICC antibodies 20.545580110496
13757 NF-κB (p65) Polyclonal Antibody (aa 2-17) - 2010-02-11 14.566101026045 nf-b-p65-polyclonal-antibody-aa-2-17 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting WB amino acids 2 7 14.566101026045
13753 NF-κB (p65) Polyclonal Antibody (aa 538-546) - 2010-02-11 19.484806629834 nf-b-p65-polyclonal-antibody-aa-538-546 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting WB amino acids 538 546 19.484806629834
10649 Niclosamide 50-65-7 ≥95% 2011-01-12 3.086436464088 niclosamide antihelminthic helminth tapeworms inhibitors STAT3 cancers proliferation anti-helminthic salicylanilide Du 145 DU145 DU-145 Niclosamide, 2-Aminoethanol (1:1) Aventis Brand of Niclosamide Bayer Brand of Niclosamide Clonitralide Niclosamide Bayluscide Bayer 2353 Trédémine Niclocide Radewerm Phenasal Bayer 73 Yomesan Fenasal 3.086436464088
10010422 Nilotinib 641571-10-0 ≥98% 2009-10-23 24.972909760589 nilotinib AMN107 tyrosine kinases inhibitors therapy cancer Bcr/Abl chronic myeloid leukemia MLL philadelphia chromosomes acute lymphoblastic ALL imatinib gleevec genes expression DNA helicase complex cyclins cyclin-dependent cells proliferation 24.972909760589
11214 NKH477 (hydrochloride) New 138605-00-2 ≥95% 2012-02-16 13.389305555556 nkh477-hydrochloride Colforsin Dapropate; Adehl 113462-26-3 adenylate cyclase adenylyl cAMP cyclic AMP vascular diseases cardiovascular cardiac hypotension hypertension analogs cardiac smooth muscles histamines forskolin 11018 HCl hydrochloride NKH-477 NKH 477 13.389305555556
11040 Nodinitib-1 New 799264-47-4 ≥95% 2012-01-20 11.548480010440 nodinitib-1 ML130; CID-1088438 NOD1 NLR innate immunity NF-κB signaling inflammation MAPK inflammatory diseases inhibitors inhibition inhibits NACHT leucine proteins bacterial bacteria ligands stress kinases interferons polymorphisms genes asthma bowel multiple sclerosis MS cells CD83 CD86 HLA-DR IL-1β IL-6 TNFα 11.548480010440
13094 N-pentadecanoyl-L-Homoserine lactone Exclusive 182359-66-6 ≥98% ✓ 2009-03-02 20.503421432482 n-pentadecanoyl-l-homoserine-lactone C15-HSL C15HSL C15-HSL AHL quorum sensing signaling signalling autoinducers bacterias 20.503421432482
10011255 NSC 210902 51726-83-1 ≥95% 2008-09-15 3.973812154697 nsc-210902 Inhibitor inhibits inhibition CK2 kinase cell signaling apoptosis cancers NSC210902 3.973812154697
13196 NSC 23766 (hydrochloride) 1177865-17-6 ≥98% 2010-07-20 18.908674033149 nsc-23766-hydrochloride 733767-34-5 GTPases cells cycles growth proliferations cell-cell adhesions motility differentiation guanine nucleotides exchange factors GEFs inhibitors inhibits inhibition cell migration Aminoquinolines angiogenesis leukemia cancers gene expression Rac1 Inhibitor 18.908674033149
10011200 N-tetradecanoyl-L-Homoserine lactone Exclusive 202284-87-5 ≥98% ✓ 2009-01-06 5.520755064456 n-tetradecanoyl-l-homoserine-lactone tDHL; C14-HSL quorum sensing bacterias biofilm gene expressions growth proteolytic acitivity activities migration 5.520755064456
10009277 Nuclear Extraction Kit - 2007-05-11 80.119260282381 nuclear-extraction-kit assays kits proteins transcription factors cytoplasmic fractions cells tissue homogenates EMSA extracts electrophoretic mobility shift western blotting blots 80.119260282381
13641 NVP-AEW541 (hydrochloride) - ≥98% 2010-07-28 41.979834254143 nvp-aew541-hydrochloride 475488-34-7 IGF-1R Insulin-like growth factor I receptors tyrosine kinases angiogenesis cells proliferation cancers inhibitors inhibition inhibits 701294-63-5 Ins-R NWT-21 Pyrroles 41.979834254143
10006803 O-1602 317321-41-8 >98% 2005-09-12 11.877928176795 o-1602 abnormal cannabidiols CB1 CB2 receptors vasorelaxation neurochemistry neuroscience central cannabinoids peripheral selective antagonists nonendothelium-dependant vasodilation nitric oxides NOs inhibits inhibitors inhibition vasorelaxant cannabinoids cbs synthetic 11.877928176795
10006804 O-1821 35482-50-9 >97% 2005-09-12 26.649907918968 o-1821 abnormal cannabidiol central cannabinoids peripheral CB1 CB2 receptors vasorelaxation neurochemistry neuroscience antagonists synthetic regioisomer endothelium dependent vasodilation cannabinoids cbs synthetic 26.649907918968
10004914 O-1918 536697-79-7 >98% 2005-09-09 11.646172059984 o-1918 antagonists abnormal cannabinoids cannabidiols cannabidiol-mediated synthetic regioisomers CB1 CB2 responsiveness psychotropics activity induces endothelium-dependent vasodilations NO-independent nitric oxides mechanisms analogs endothelial receptors inhibits inhibition inhibitors vasorelexants in vitro blocks induced activations PI3-kinases Akt pathway umbilical vein cells neuroscience neurochemistry O1918 0-1918 cannabinoids cbs synthetic 11.646172059984
10010299 Oleoyl 3-carbacyclic Phosphatidic Acid Exclusive - ≥95% ✓ 2009-10-14 15.632520718232 oleoyl-3-carbacyclic-phosphatidic-acid 3-ccPA 18:1 cyclic phosphatidic acids cPAs lysophosphatidic LPA ccPA 3ccPA oleate transcellular migration MM1 cells mesothelial autotoxin cancer survival growth migration invasion metastasis antagonist LPA1 LPA2 LPA3 476310-24-4 15.632520718232
9000629 Oleoyl Serotonin Exclusive 1002100-44-8 ≥98% ✓ 2010-05-18 6.570323599053 oleoyl-serotonin N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA Hydrolase Long-Chain Fatty-Acyl-CoA Fatty-Acyl-CoA Hydrolase Long-Chain Long-Chain Fatty-Acyl-CoA Hydrolase Long Chain Fatty Acyl CoA Hydrolase Palmitoyl Coenzyme A Hydrolase Acylhydrolase Oleoyl-CoA Thioesterase Fatty Acyl Oleoyl-CoA Acylhydrolase Oleoyl CoA Acylhydrolase Hydrolase Palmitoyl-CoA Deacylase, Palmitoyl CoA CoA Deacylase, Palmitoyl Thioesterase, Palmitoyl Palmitoyl-CoA Hydrolase Palmitoyl CoA Hydrolase Palmitoyl CoA Deacylase Hydrolase Stearoyl CoA Fatty Acyl Thioesterase CoA Hydrolase Stearoyl Stearoyl CoA Hydrolase Palmitoyl Thioesterase Hydrolase Acyl CoA CoA Hydrolase Acyl Acyl CoA Hydrolase Thioesterase I 6.570323599053
9000694 Oleoyl Serotonin-d17 Exclusive - ≥99% deuterated forms (d1-d17) ✓ 2010-09-27 6.470165745857 oleoyl-serotonin-d17 N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA deuterateds deuteriums MS mass spectrometry GC-MS LC-MS GC/MS LC/MS standards 6.470165745857
10011301 p38 MAPK Monoclonal Antibody (Clone 9F12) - 2008-05-22 3.323351749539 p38-mapk-monoclonal-antibody-clone-9f12 p38 Mitogen-activated Protein Kinase; p38 MAPKα serine threonine serine-threonine cell cycles development apotosis kinases stress signals cytokines gene expression western blots immunoblotting immunocytochemisty ICC WB flow cytometry signal transduction signalling signaling blotting FC 3.323351749539
600008 p53 Cell-Based Activation/Translocation Assay Kit - 2009-03-10 4.725874769798 p53-cell-based-activation-translocation-assay-kit p53 dsDNA double-stranded tumors suppressors proteins guardians of the genomes cells cellular responses genotoxic stresses activity cycles arrests apoptosis senescence humans cancers mutations inactivated binding ubiquitination acetylation phosphorylation sumoylation neddylation methylation glycosylation damages oncogenes ribosomal cell-matrix matrices adhesion hypoxia p21 WAF1 Cip1 MDM2 GADD45 Cyclin G Bax IGF-BP3 bcl-2 Bcl-XL cyclins B1 MAP4 survivin HPV16 PARP-1 WT1 E1b/E4 degradation nucleus cytoplasms proteasomes promoter carcinogenesis endogenous wild-type heterogenous autosomal dominant disorders Li Fraumeni Syndromes nuclear extracts assays cell-based assay cell based assay cba 4.725874769798
10007358 Palmitic Acid methyl ester 112-39-0 >99% 2006-02-17 17.079586883568 palmitic-acid-methyl-ester MP; Methyl Palmitate esters saturated fatty acids synthesized synthesis plants animals acetyl coenzymes CoA energy storage 16-carbon dietary fats plasma lipoproteins expression COX-2 cyclooxygenase-2 cyclooxygenases proteins acylation lipids anchoring signaling signalling molecules 17.079586883568
10010298 Palmitoleoyl 3-carbacyclic Phosphatidic Acid Exclusive 910228-13-6 ≥95% ✓ 2009-11-03 11.081066723331 palmitoleoyl-3-carbacyclic-phosphatidic-acid 3-carbacyclic PA; 3-ccPA 16:1 cyclic phosphatidic acids cPAs lysophosphatidic LPA ccPA 3ccPA palmitoleate transcellular migration MM1 cells mesothelial autotoxins cancer survival growth migration invasion metastasis NPP2 ENPP2 ectonucleotide pyro phosphatase/phosphodiesterase 2 11.081066723331
10965 Palmitoleoyl Ethanolamide 94421-67-7 ≥98% 2011-06-27 20.839465930018 palmitoleoyl-ethanolamide POEA cannabinoids endocannabinoids CBs N-acylethanolamines signalling N-acylethanolamides NAEs signaling receptors pain lipid-derived 20.839465930018
10010293 Palmitoyl 3-carbacyclic Phosphatidic Acid Exclusive 476310-22-2 ≥95% ✓ 2009-10-07 15.241019588146 palmitoyl-3-carbacyclic-phosphatidic-acid 3-ccPA 16:0 cyclic acids cPAs lysophosphatidic LPA ccPA 3ccPA palmitate transcellular migration MM1 cells mesothelial autotoxins cancers survival growth migration invasion metastasis 15.241019588146
9000630 Palmitoyl Serotonin Exclusive 212707-51-2 ≥98% ✓ 2010-05-18 7.061310181531 palmitoyl-serotonin N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA Hydrolase Long-Chain Fatty-Acyl-CoA Fatty-Acyl-CoA Hydrolase Long-Chain Long-Chain Fatty-Acyl-CoA Hydrolase Long Chain Fatty Acyl CoA Hydrolase Palmitoyl Coenzyme A Hydrolase Acylhydrolase Oleoyl-CoA Thioesterase Fatty Acyl Oleoyl-CoA Acylhydrolase Oleoyl CoA Acylhydrolase Hydrolase Palmitoyl-CoA Deacylase Palmitoyl CoA CoA Deacylase Palmitoyl Thioesterase Palmitoyl Palmitoyl-CoA Hydrolase Palmitoyl CoA Hydrolase Palmitoyl CoA Deacylase Hydrolase Stearoyl CoA Fatty Acyl Thioesterase CoA Hydrolase Stearoyl Stearoyl CoA Hydrolase Palmitoyl Thioesterase Hydrolase Acyl CoA CoA Hydrolase Acyl Acyl CoA Hydrolase Thioesterase I 7.061310181531
11345 Paxilline New 57186-25-1 ≥98% 2012-03-01 10.565642497180 paxilline (+)-Paxilline Paxicillin Paxillin inhibitors inhibits inhibitions channels K+ blockers potassium BKCa cells signaling smooth muscle vascular cardiovascular neuronal neuroscience 10.565642497180
10994 Paxillin (Phospho-Tyr118) Polyclonal Antibody New - 2012-01-13 0E-12 paxillin-phospho-tyr118-polyclonal-antibody proteins LIM domains ERK-regulated scaffolds vinculin-binding phosphorylation Western blots blotting WB ERKs binds binding vinculin JNK 0E-12
13034 PD 0325901 391210-10-9 ≥98% 2009-03-13 45.531495720653 pd-0325901 MEK ERK RAS RAF MAPK tumors stem cells cancers differentiation signaling GSK3 kinase inhibitors inhibits inhibition pd325901 pd 325901 PD0325901 45.531495720653
9000988 PD 166326 New 185039-91-2 ≥98% 2011-11-30 13.817691869969 pd-166326 inhibitors cancers c-abl c-src Bcl/Abl tyrosine receptors kinases cells signaling leukemia CML chronic myelogenous leukemia PD-166326 PD166326 pyridopyrimidine STI571 mesylate 13.817691869969
10006727 PD 169316 152121-53-4 >98% 2006-04-12 12.142879411785 pd-169316 p38 mitogen-activated proteins kinases MAPK enzymes signal transductions inhibitors inhibits A C.alpha. apoptosis neuronal cells trophic factors potassium nerves growth pd169316 pd-169316 12.142879411785
13032 PD 173074 219580-11-7 ≥98% 2009-07-29 48.426305915947 pd-173074 fibroblast growths factors receptors FGFRs FGFR1 tyrosine kinase activity activities activation signals propagation inhibitors inhibition inhibits autophosphorylation PDGFR c-Src cSrc c Src EGFR InsR MEK PKC FGFR2 FGFR3 FGFR4 FGFR5 angiogenesis cancers tumors self-renewal self renewal stems cells ERK1/2 ERK-1/2 ERK 1/2 48.426305915947
10012431 PD 184161 Exclusive 212631-67-9 ≥98% ✓ 2009-06-09 12.113645758542 pd-184161 MEK inhibitors MAP kinase ERK signaling cancer MEK 1/2 inhibition inhibited ERK 1/2 potent selective pd184161 12.113645758542
10006726 PD 98059 167869-21-8 >98% 2005-09-12 17.671676392078 pd-98059 potent selective MAPK mitogen-activated proteins kinases family serines threonines cellular PD-98059 programs cells proliferation differentiation movement death noncompetitive inhibits inhibitors inhibition pathways activation MAPKK1 Raf MEK MAPKK2 MAPKK-1 PD98059 MAPKK-2 ERK 17.671676392078
11347 Penitrem A New 12627-35-9 ≥98% 2012-03-05 16.753229974160 penitrem-a Tremortin A; NSC 354845 12679-82-2 inhibitors inhibits inhibition channels blockers potassium BKCa cells signaling smooth muscles vascular cardiovascular neuronal neuroscience SLO1 Maxi-K fungal fungus toxins 16.753229974160
10007191 PH Domain Leucine-rich Repeat Protein Phosphatase 1 Polyclonal Antibody - 2006-01-04 5.081698895027 ph-domain-leucine-rich-repeat-protein-phosphatase-1-polyclonal-antibody Suprachiasmatic Nucleus Circadian Oscillatory Protein; SCOP; PLEKHE1 Protein; PHLPP1; KIAA0606 Protein proteins diseases antibodies antisera antiserum western blots blotting immunocytochemistry ICC immunohistochemistry IHC cancers WB immunoblotting PH Domain Leucine-rich Repeat Protein Phosphatase Polyclonal Antibody 5.081698895027
10007192 PH Domain Leucine-rich Repeat Protein Phosphatase Blocking Peptide - 2006-01-30 4.502071823204 ph-domain-leucine-rich-repeat-protein-phosphatase-blocking-peptide Suprachiasmatic Nucleus Circadian Oscillatory Protein; SCOP; PLEKHE1 Protein; PHLPP; KIAA0606 Protein western blotting blots signaling signalling WB IHC ICC immunohistochemistry formalin-fixed paraffin-embedded immunocytochemistry proteins kinases Akt cells growth death serine residues Ser473 C-terminal hydrophobic motifs human cancers dephosphorylates dephosphorylation reduces activity apoptosis apoptotic colon glioblastomas lines tumors brain 4.502071823204
13581 Phosphine-biotin - ≥95% 2009-12-03 24.707853474736 phosphine-biotin DAz-1 DAz1 DAz 1 DAz-2 DAz2 DAz 2 sulfenic acids click chemistry azido groups ROS oxidation cysteine posttranslational modifications staudinger ligation P-Biotin click-tag 24.707853474736
10009209 PI-103 371935-74-9 ≥98% 2007-01-19 22.568281495123 pi-103 phosphoinositides PI3-kinases Phosphatidylinositols cancers Glioma DNA-PK mTOR inhibitors inhibits inhibition anti-proliferatives proliferation PI103 22.568281495123
13326 Pifithrin-α 63208-82-2 ≥95% 2009-07-16 26.307106353591 pifithrin p53 apoptosis DNA damage cyclin D1 C8 cells HUVECs endothelial cells dependent independent inactivator 26.307106353591
10009210 PIK-75 372196-67-3 ≥98% 2010-03-10 13.776209126253 pik-75 p110α PI3K insulin signaling signals cancers inhibitors inhibits inhibition signalling p110a phosphatidylinositol 3-kinase phosphorylation Akt activation mTORC1 PIP2 PIP3 p110β p110α p110γ p110beta p110 alpha p110.beta. p110.alpha. p110gamma p110.gamma.p110g Mixtures, Sulfonamide Sulfonamide Mixtures Sulfonamides 13.776209126253
11006 Piperlongumine 20069-09-4 ≥98% 2011-10-24 57.444354076548 piperlongumine Piplartine 2859-009- 11042-67-4 25343-05-9 Keap1 Nrf2 antioxidants ROS cancers redox platelet aggregation tumorigenesis 57.444354076548
10728 PIT-1 Exclusive 53501-41-0 ≥98% ✓ 2011-03-25 11.615028182376 pit-1 PIP3 PtdIns-(3,4,5)-P3 PH domains cancers inhibitors Akt PDK1 PTENs proteins binding pituitary-specific transcription factors pit-1 pituitary-specific pit 1 GHF-1 GHF 1 pit-oct-unc pit oct unc POU growth hormones 11.615028182376
10459 PKC 412 120685-11-2 ≥98% 2010-07-27 25.560131929891 pkc-412 CGP 41251; N-Benzoylstaurosporine; Midostaurin; CGP 41231 inhibitors inhibits inhibition PKC412 PKC-412 serine/threonine serine threonine tyrosines kinases PKCα PKCβ PKCγ PKC-α PKC-β PKC-γ Syk Flk-1 Flk1 Akt PKA c-Kit cKit C-Fgr cFgr FLT3 FLT-3 PDFRβ PDFR-β VEGFR1 VEGF2 nitric oxide synthase eNOS apoptosis cancers angiogenesis signal transduction Staurosporine 25.560131929891
10007839 PLC thio-PIP2 (sodium salt) - >98% 2006-01-18 12.186710734017 plc-thio-pip2-sodium-salt phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono 12.186710734017
13198 PP2 172889-27-9 ≥98% 2010-09-20 28.396000000000 pp2 AGL 1879 PTK inhibitors inhibits inhibition Src kinase T cells T-cells enzymes AG1879 AG 1879 PP-2 PP 2 signalling tyrosine kinases tyrosine focal Tyr 577 adhesion kinases AG-1879 AGL1879 AGL 1879 thaliana Proteins Arabidopsis Proteins Arabidopsis thaliana Arabidopsis thaliana Proteins Hemagglutinins Plant Thale Cress Proteins Plant Hemagglutinins Arabidopsis Proteins Agglutinins Plant Plant Agglutinins Proteins Plant Phytagglutinins Plant Proteins Lectins Plant Plant Lectins 28.396000000000
10272 Prostratin 60857-08-1 ≥98% 2009-06-11 34.766055248618 prostratin SA 101A; NSC 623310; 13-O-Acetylphorbol HIV-1 AIDS NF-κB PKC T cells CD4 CXCR4 CCR5 stillingia factor S7 SFS7 13-O-acetyl-12-deoxy phorbol 34.766055248618
10011237 Protein Phosphatase 2A C subunit (human recombinant; L309 deletion) Exclusive - ✓ 2008-07-17 27.116464088398 protein-phosphatase-2a-c-subunit-human-recombinant-l309-deletion PP2A Cα; PP2A Δ309; PP2A L309 proteins phosphatases serine threonine cellular tumors enzyme kinetics regulations substrates phosphorylasion PP2As octahistidine-tag streptactin-tag active 27.116464088398
10010896 Protein Tyrosine Phosphatase 1B (human recombinant) - ≥95% 2008-08-25 11.069127071823 protein-tyrosine-phosphatase-1b-human-recombinant PTP1B proteins recombinant PTPs phosphates tyrosines pNPP enzymes diabetes insulin leptin signaling signalling active 11.069127071823
10009506 PSD95 Polyclonal Antibody - 2007-01-03 0.392265193370 psd95-polyclonal-antibody Postsynaptic Density Protein of 95 antibodies WB western blot PDZ domain glutamate receptors signaling proteins synapse NMDAR phosphorylation proteins signalling blotting immunoblotting 0.392265193370
9000660 PtdIns-(1,2-dihexanoyl) (sodium salt) Exclusive - ≥98% ✓ 2010-09-24 11.859666603162 ptdins-1-2-dihexanoyl-sodium-salt 1051393-51-1 phosphatidylinositols triphosphates cells signaling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PLS 11.859666603162
10008099 PtdIns-(1,2-dioctanoyl) (sodium salt) - ≥98% 2006-01-17 16.410645224940 ptdins-1-2-dioctanoyl-sodium-salt Phosphatidylinositol C-8; DOPI phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 16.410645224940
10007710 PtdIns-(1,2-dipalmitoyl) (ammonium salt) - ≥98% 2005-12-30 17.227729091255 ptdins-1-2-dipalmitoyl-ammonium-salt DPPI; Phosphatidylinositol C-16 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 17.227729091255
9000305 PtdIns-(1-arachidonoyl, 2-arachidonoyl-d8) (ammonium salt) Exclusive - ≥99% deuterated forms (d1-d8) ✓ 2009-04-20 15.698350828729 ptdins-1-arachidonoyl-2-arachidonoyl-d8-ammonium-salt arachidonic acids deuterium atoms AA GC/MS LC/MS mass spectrometry deuterateds 15.698350828729
10008390 PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt) - ≥98% 2009-02-03 13.590628859278 ptdins-3-4-5-p3-1-2-dihexanoyl-ammonium-salt Phosphatidylinositol-3,4,5-triphosphate C-6; DHPI-3,4,5-P3; PIP3C-16 phosphatidylinositols cell signalling pleckstrin homology protein binding PIP3 PtdIns phospholipid signal transduction C6 C-6 13.590628859278
10007764 PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt) - ≥98% 2005-12-30 13.203405914851 ptdins-3-4-5-p3-1-2-dioctanoyl-sodium-salt Phosphatidylinositol-3,4,5-trisphosphate; DOPI-3,4,5-P3 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP3 mono PIPs 13.203405914851
9000414 PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl)-d62 (sodium salt) Exclusive - ≥98% ✓ 2009-09-25 14.484466638334 ptdins-3-4-5-p3-1-2-dipalmitoyl-d62-sodium-salt Phosphatidylinositol-3,4,5-trisphosphate C-16-d62; DPPI-3,4,5-P3-d62 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids PIPs phosphatidylinositols triphosphates phospholipases PLC PLD analogs deuterium GC/MS internal isotopes standards GC-MS LC/MS LC-MS mass spectrometry deuterated diacyl glycerols DAG PIP3 mono di 14.484466638334
10009531 PtdIns-(3,4,5)-P3-biotin (sodium salt) Exclusive - ≥98% ✓ 2007-01-16 11.099097605893 ptdins-3-4-5-p3-biotin-sodium-salt Phosphatidylinositol-3,4,5-triphosphate C-8-biotin; PIP3-biotin phosphatidylinositols triphosphates phospholipids phophorylation intracellular signals transduction PIP2 biotinimides dioctanoyl PTEN PI3k affinity probes ligands detection transmembranes receptors nucleic acids proteins binding kinases biotins biotinylated 11.099097605893
10010383 PtdIns-(3,4,5)-P3-fluorescein (ammonium salt) Exclusive - ≥95% ✓ 2008-08-13 15.953129439620 ptdins-3-4-5-p3-fluorescein-ammonium-salt PIPs PIP3-fluorescein fluorescent PI3K PTENs phosphatidylinositol phosphates phosphorylated kinases binding proteins PIPs 15.953129439620
10007759 PtdIns-(3,4)-P2 (1,2-dihexanoyl) (sodium salt) - ≥98% 2005-12-30 12.787000534663 ptdins-3-4-p2-1-2-dihexanoyl-sodium-salt Phosphatidylinositol-3,4-bisphosphate C-6; DHPI-3,4-P2 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono PIPs 12.787000534663
10008400 PtdIns-(3,4)-P2 (1,2-dioctanoyl) (sodium salt) - ≥98% 2006-11-16 11.710108655616 ptdins-3-4-p2-1-2-dioctanoyl-sodium-salt Phosphatidylinositol-3,4-bisphosphate C-8; DOPI-3,4-P2 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono PIPs 11.710108655616
10008396 PtdIns-(3,5)-P2 (1,2-dihexanoyl) (sodium salt) - >98% 2008-01-21 11.859666603162 ptdins-3-5-p2-1-2-dihexanoyl-sodium-salt Phosphatidyl-3,5-bisphosphate C-6; DHPI-3,5-P2 phosphatidyl inositols IP3 diacylglycerol DAG PIP1 PIP2 PIP3 signal transductions phospholipases C phospholipases D PLC PLD PIPs 11.859666603162
10007763 PtdIns-(3,5)-P2 (1,2-dioctanoyl) (sodium salt) - ≥98% 2005-12-30 12.368515653774 ptdins-3-5-p2-1-2-dioctanoyl-sodium-salt Phosphatidylinositol-3,5-bisphosphate C-8; DOPI-3,5-P2 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono PIPs 12.368515653774
10008398 PtdIns-(3,5)-P2 (1,2-dipalmitoyl) (sodium salt) - ≥98% 2007-11-28 12.788210657637 ptdins-3-5-p2-1-2-dipalmitoyl-sodium-salt Phosphatidylinositol-3,5-diphosphate C-16 phosphatidylinositols diphosphates phospholipids phophorylation signal transduction IP3 diacylglycerol DAG PIP1 PIP2 PIP3 PLC PLD 12.788210657637
10008394 PtdIns-(3)-P1 (1,2-dioctanoyl) (sodium salt) - ≥98% 2007-06-11 14.764593255858 ptdins-3-p1-1-2-dioctanoyl-sodium-salt Phosphatidylinositol-3-monophosphate C-8; DOPI-3-P1 phosphatidyl inositols IP3 diacylglcerol DAG PIP1 PIP2 PIP3 transuction C phospholipase D PLC PLD signaling signalling 14.764593255858
10005616 PtdIns-(3)-P1 (1,2-dipalmitoyl)-d62 (ammonium salt) - ≥99% deuterated product 2005-12-30 13.982187083253 ptdins-3-p1-1-2-dipalmitoyl-d62-ammonium-salt DPPI-3-P-d62; Phosphatidylinositol-3-phosphate C16-d62 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs deuterium GC/MS internal isotopes standards GC-MS LC/MS LC-MS mass spectrometry deuterated diacyl glycerols DAG PIP1 triphosphates mono 13.982187083253
10007762 PtdIns-(4,5)-P2 (1,2-dihexanoyl) (sodium salt) - ≥98% 2005-12-30 15.920101864641 ptdins-4-5-p2-1-2-dihexanoyl-sodium-salt Phosphatidylinositol-4,5-bisphosphate C-6; DHPI-4,5-P2 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono PIPs 15.920101864641
10008115 PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (sodium salt) - ≥98% 2006-01-17 27.038152624309 ptdins-4-5-p2-1-2-dipalmitoyl-sodium-salt Phosphatidylinositol-4,5-diphosphate C-16; DPPI-4,5-P2 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono 27.038152624309
10005615 PtdIns-(4,5)-P2 (1,2-dipamitoyl)-d62 (sodium salt) - ≥99% deuterated product 2006-01-30 15.227603059923 ptdins-4-5-p2-1-2-dipamitoyl-d62-sodium-salt Phosphatidylinositol-4,5-diphosphate C16-d62; DPPI-4,5-P2-d62 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs deuterium GC/MS internal isotopes standards GC-MS LC/MS LC-MS mass spectrometry deuterated diacyl glycerols DAG PIP2 triphosphates mono di 15.227603059923
10008159 PtdIns-(4,5)-P2-biotin (sodium salt) - ≥98% 2006-12-21 22.575276243093 ptdins-4-5-p2-biotin-sodium-salt Phosphatidylinositol-4,5-diphosphate C-8-biotin phosphatidylinositols diphosphates phospholipids phophorylation intracellular signals transduction PIP2 biotinimides dioctanoyl PTEN PI3k affinity probes ligands detection transmembranes receptors nucleic acids proteins binding kinases PIPs biotins biotinylated 22.575276243093
10010388 PtdIns-(4,5)-P2-fluorescein (ammonium salt) Exclusive - ≥95% ✓ 2008-08-14 45.616896869244 ptdins-4-5-p2-fluorescein-ammonium-salt PIPs PIP2 fluoresceins fluorescent PI3K PTEN probes 45.616896869244
10007757 PtdIns-(4)-P1 (1,2-dihexanoyl) (sodium salt) - ≥98% 2005-12-30 14.515924077704 ptdins-4-p1-1-2-dihexanoyl-sodium-salt DHPI-4-P1; Phosphatidylinositol-4-phosphate C-6 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 14.515924077704
10007711 PtdIns-(4)-P1 (1,2-dioctanoyl) (ammonium salt) - ≥97% 2005-12-30 12.642461236856 ptdins-4-p1-1-2-dioctanoyl-ammonium-salt DOPI-4-P1; Phosphatidylinositol-4-phosphate C-8 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 12.642461236856
10008050 PtdIns-(5)-P1 (1,2-dihexanoyl) (sodium salt) - ≥98% 2005-12-30 11.847904235727 ptdins-5-p1-1-2-dihexanoyl-sodium-salt Phosphatidylinositol-5-phosphate; DHPI-5-P1 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 11.847904235727
10007758 PtdIns-(5)-P1 (1,2-dioctanoyl) (ammonium salt) - ≥98% 2005-12-30 11.847904235727 ptdins-5-p1-1-2-dioctanoyl-ammonium-salt DOPI-5-P1; Phosphatidylinositol-5-phosphate C-8 phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 11.847904235727
10010181 Ptd(S)Ins-(3,4)-P2 (1,2-dioctanoyl) (sodium salt) - ≥95% 2008-01-07 12.163724518956 ptd-s-ins-3-4-p2-1-2-dioctanoyl-sodium-salt DOsPI-3,4-P2 phospholipases C PIP2 PtdIns inositols phosphate PLC phosphothiotidyls Ellmans reagent analogs PIPs 12.163724518956
10009746 PTEN (human recombinant) - ≥95% 2008-09-04 2.475679558010 pten-human-recombinant TEP1; Phosphatidylinositol 3-phosphatase; MMAC1; Phosphatase and Tensin Homology on Chromosome 10 proteins PTENs phosphatase homology tensin chromosomes enzymes lipids Sf21 cells recombinant N-terminal tumor suppressor cancers phosphoinositide hexahistidine His-tag His-tagged active 2.475679558010
10005059 PTEN Polyclonal Antibody - 2005-05-04 11.135635359116 pten-polyclonal-antibody TEP1; Phosphoinositide 3-phosphatase; MMAC1; Phosphatase and Tensin Homolog on Chromosome 10 proteins antibodies antisera antiserum wb western blots blotting IHC immunohistochemistry dephosphorylates lipids AKT phosphatidylinositols triphosphates PIP3 tissues acids regulates cells division migrations apoptosis mutations cancers melanomas prostates carcinomas A431 HEK293 signals transductions cancers endocrinology immunoblotting 11.135635359116
10009747 PTEN Western Ready Control - 2007-05-30 0.421731123388 pten-western-ready-control TEP1; MMAC1; Phosphatidylinositol 3-phosphatase; Phosphatase and Tensin Homology on Chromosome 10 western blot WB AKT phosphatidylinositol 3,4,5-triphosphate PIP3 enzyme transduction pathway endocrinology 0.421731123388
13294 Pyrrophenone 341973-06-6 ≥90% 2010-04-07 48.304680347276 pyrrophenone phospholipase A2 group IVA phospholipase A2 PLA2 cytosolic PLA2 cPLA2 arachidonic acid AA prostaglandins PG leukotrienes LT inhibitors PGE2 LTB4 blood secretory type PLA2 sPLA2 inflammation inhibition inhibits inflammatory Pyrrolidines 48.304680347276
10009504 Raf-1 (Phospho-Ser301) Polyclonal Antibody - 2006-12-21 2.004779005524 raf-1-phospho-ser301-polyclonal-antibody phospho-specific antibodies proteins WB western blots blotting signal transduction Ras protein kinase MEK ERK phosphorylation Raf serine threonine cellular proliferation phospho-specific immunoblotting 2.004779005524
10009505 Raf-1 (Phospho-Ser642) Polyclonal Antibody - 2006-12-22 4.009558011049 raf-1-phospho-ser642-polyclonal-antibody phospho-specific antibodies proteins WB western blot blotting signal transduction Ras protein kinase MEK ERK phosphorylation Raf serine threonine cellular proliferation immunoblotting 4.009558011049
13346 Rapamycin 53123-88-9 ≥95% 2009-10-21 44.025417638632 rapamycin Sirolimus immunosuppresssants transplants rejection inhibitors IL-2 lymphocytes B cells T FKBP12 mTOR mTORC1 cancer adipogenesis diabetes tuberous sclerosis cardiovascular diseases 44.025417638632
10009411 Ribosomal S6 Kinase 2 Polyclonal Antibody - 2006-11-28 0.435082872928 ribosomal-s6-kinase-2-polyclonal-antibody RSK2 wb western blotting blots antibodies p90 kinases RSK1 RSK2 RSK3 RSK4 downstream members extracellular signal-regulated ERK/MAPK cascade humans Coffin-Lowry syndrome mental retardation growth deficits defects tonic regulation GPCRs G protein-coupled signalling immunoblotting 0.435082872928
13300 Ro 31-6045 113963-68-1 ≥98% 2009-07-28 11.995243484569 ro-31-6045 Bisindolylmaleimide V PKC kinase inhibitors S6K mitogen-stimulated proteins p70 p85 protein kinases C 11.995243484569
13333 Ro 31-7549 (acetate) 138516-31-1 ≥98% 2009-07-30 11.911528325192 ro-31-7549-acetate Bisindolylmaleimide VIII PKC isozyme inhibitors phospholipases cells signalling signaling SH-SYSY neuroblastoma 125313-65-7 inhibits inhibitions 11.911528325192
13334 Ro 31-8220 (mesylate) 138489-18-6 98% 2009-10-28 23.479260025799 ro-31-8220-mesylate Bisindolylmaleimide IX bisindolylmaleimide inhibitor protein kinase C PKC PKC-α PKC-βI PKC-βII PKC-γ PKC-ε PKA CaM kinase II glycogen synthase kinase-3 GSK-3 Ro318220 GSK3 125314-64-9 Ro-31-8220 75-75-2 23.479260025799
13343 RSC-3388 337307-06-9 ≥95% 2010-02-15 10.927624309392 rsc-3388 cytosolic phospholipases A2 cPLA2 cPLA2α arachidonic acids eicosanoids platelet-activating factors PAF inhibitors inhibits inhibition inflammation dermatitis acrylamides 10.927624309392
13067 SB 203580 152121-47-6 ≥98% 2009-01-14 25.219138121546 sb-203580 RWJ 64809; PB 203580 MAPKs signal transduction p38 kinases cytokines inflammation immune response PI3-kinase PDK1 apoptosis inhibitors inhibits inhibition sb203580 25.219138121546
13344 SB 203580 (hydrochloride) 869185-85-3 ≥98% 2009-09-08 18.550865561694 sb-203580-hydrochloride PB 203580; RWJ 64809 inhibitors inhibits inhibitions MAPK signal transduction p38 kinase PI3 PDK1 18.550865561694
13336 SB 225002 182498-32-4 ≥95% 2009-07-08 101.920939226519 sb-225002 CXCR2 IL-8RB IL-8 CXCL8 Gro-α CXCL1 inflammation chemokines neutrophils angiogenesis inhibitors colitis chemotaxis IL8 IL8RB Groα inhibition inhibits sb225002 101.920939226519
10010247 SB 415286 264218-23-7 ≥98% 2008-10-29 12.584364640884 sb-415286 GSK3 GSK-3 PI3K signaling PI3K signalling glycogen synthase inhibitors inhibits inhibition neuron survival glycogen synthesis Chang human liver cells line potent selective sb415286 12.584364640884
13031 SB 431542 301836-41-9 ≥98% 2009-08-10 104.892580110497 sb-431542 inhibitors inhibits inhibitions TGF-β1 TGFβ1 receptors ALK5 ALK4 ALK7 ALKs BMP ALK2 ALK3 ALK6 kinases Smad fibrosis cancers renewal embryonic stems cells induced pluripotent differentiation SB431542 104.892580110497
10009557 SC-1 - ≥98% 2008-08-11 25.277182320442 sc-1 Pluripotin stem cells embryonic ras signal transduction ERK1 ERK2 ERK-1 ERK-2 PI3-kinase differentiation self-renewal selfrenewal SC1 SC 1 25.277182320442
10010267 SC-514 354812-17-2 ≥98% 2009-08-07 30.175450747877 sc-514 SC514 SC 514 inhibitors inhibits inhibitions IκB kinase IkB IKK2 NF-κB NFκB IL-1β IL1β genes expressions IL-6 IL6 IL-8 IL8 COX-2 COX2 iNOS LPS smooth muscles cells TLR2 TNF astrocytes 30.175450747877
13332 (S)-Glycyl-H-1152 (hydrochloride) Exclusive 913844-45-8 ≥98% ✓ 2010-01-27 83.825403314916 -s-glycyl-h-1152-hydrochloride Rho Kinase Inhibitor IV Rho kinases ROCK-I p160ROCK ROCK-II G protein Rho cytoskeletons adhesions proliferation smooth muscles contraction stem cells inhibitors inhibition inhibited Fasudil hydrochloride ROCK IV h1152 h-1152 h 1152 83.825403314916
10007653 (S)-H-1152 (hydrochloride) 451462-58-1 ≥95% 2010-02-25 31.991988950276 -s-h-1152-hydrochloride Rho kinase ROCK cytoskeletal cytoskeleton smooth muscles contractions vasoconstriction neurons neurite inhibitors Y-27632 HA-1077 PKA PKC MLCK H1152 H 1152 inhibition inhibits 451462-58-1 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine H-7 H 7 h1152 h-1152 h 1152 31.991988950276
10009312 SKF-96365 (hydrochloride) 130495-35-1 ≥98% 2007-01-19 47.533237569061 skf-96365-hydrochloride calcium antagonists voltage-gated inhibits inhibitors inhibition acetylcholine-induced depolarization smooth muscles platelets neutrophils SFK9635 Ach-induced HCl neurochemistry 47.533237569061
10007974 SLF Exclusive - ≥98% ✓ 2006-04-14 25.340957642725 slf Synthetic Ligand of FKBP FK-506 synthetic binding proteins FKBP12 ligands immunosuppressants inhibits calcium/calmodulin-dependent phosphatases calcineurins T-cells cell-permeable analogs homodimers heterodimers dimerization ligand-specific fusion signaling monomers 10-atoms linkers Fas 25.340957642725
10822 SMAD1/5/8/9 Polyclonal Antibody - 2011-04-14 0.753496448303 smad1-5-8-9-polyclonal-antibody WBs western blots immunoblotting SMADs 1 5 8 9 SMAD-1-5-8-9 1/5/8/9 antibodies serum 1,5,8,9 0.753496448303
10821 SMAD1/5/8/9 Polyclonal Antiserum - 2011-03-31 0.753496448303 smad1-5-8-9-polyclonal-antiserum WBs western blots immunoblotting SMADs 1 5 8 9 SMAD-1-5-8-9 1/5/8/9 antibodies serum 0.753496448303
10823 SMAD2 Polyclonal Antibody - 2011-05-05 0.753496448303 smad2-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-2 SMAD 2 antibodies serum IHC immunohistochemistry TGF-β TGFβ cancers 0.753496448303
10832 SMAD3 Polyclonal Antibody - 2011-05-03 0.659309392265 smad3-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-3 SMAD 3 antibodies serum IHC immunohistochemistry TGF-β TGFβ Tcells signaling TGF-β MH1 domains DNA proteins SARA ECM apoptosis proliferation differentiation 0.659309392265
10838 SMAD4 Polyclonal Antibody - 2011-05-05 2.900856353591 smad4-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-4 SMAD 4 antibodies serum IHC immunohistochemistry TGF-β TGFβ cancers 2.900856353591
10839 SMAD6 Polyclonal Antibody - 2011-05-02 1.814269928965 smad6-polyclonal-antibody WBs western blots immunoblotting SMADs MAD SMAD-6 SMAD 6 antibodies serum IHC immunohistochemistry TGF-β TGFβ Tcells intracellular proteins signaling serine threonine apoptosis bones cancers genes signal transduction 1.814269928965
10845 SMAD7 Polyclonal Antibody - 2011-05-05 0.753496448303 smad7-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-7 SMAD 7 antibodies serum TGF-β TGFβ Tcells 0.753496448303
10840 SMAD7 Polyclonal Antibody (azide-free) - 2011-05-05 1.950055248618 smad7-polyclonal-antibody-azide-free WBs western blots immunoblotting SMADs SMAD-7 SMAD 7 antibodies serum TGF-β TGFβ Tcells 1.950055248618
11029 SMI-4a New 327033-36-3 ≥95% 2012-03-14 20.000000000000 smi-4a serine/threonine kinases Pim cancers rapamycin-sensitive mammalian target of rapamycin mTORC1 AMPK leukemia inhibitors inhibits inhibition SMI4a SMI 4a cells myeloid lymphoid T-cells T cells lymphoma apoptosis tumors Ser/Thr 20.000000000000
10012555 Sodium Hydrogen Sulfide (hydrate) 207683-19-0 ≥65% 2009-09-03 16.287560088776 sodium-hydrogen-sulfide-hydrate Sodium Hydrosulfide; NSC 158264; NaHS hydrogen sulfide H2S donor inflammation oxidative stress cardiocascular neurological neurons pulmonary leukocytes neutrophils pain 1310-76-5 64568-18-9 111883-06-8 16721-80-5 16.287560088776
10010466 SP 600125 129-56-6 ≥98% 2009-01-07 11.780883977900 sp-600125 1PMV; Pyrazolanthrone; NSC 75890 c-Jun cJun JNKs inhibitors inhibits inhibition reversible cell-permeable cells COX-2 COX2 MAP kinase MAPK genes expressions apoptosis autophagy differentiation IL-10 IL10 TNF-α TNFα IFN-γ IFNγ T-cells Tcells HeLa sp600125 11.780883977900
13339 SQ 22,536 New 17318-31-9 ≥95% 2012-05-09 34.665580110497 sq-22-536 NSC 53339 inhibitors inhibits inhibition adenylyl cyclases cAMP platelets iloprost vasorelaxation pulmonary veins vascular smooth muscles prostaglandins PGs PGE PGE1 E1 SQ 22536 SQ22,536 SQ-22,536 34.665580110497
13337 ST638 107761-24-0 ≥98% 2010-09-21 24.500860299921 st638 tyrosine kinases inhibitors inhibits inhibition cell signaling signalling receptors tumor necrosis factor phosphorylation TNF-α phorbol myristate acetate PMA cardiac fibroblasts TNFα TNF α TNFalpha TNF.alpha. 24.500860299921
9000631 Stearoyl Serotonin Exclusive 67964-87-8 ≥98% ✓ 2010-05-18 6.930797158643 stearoyl-serotonin N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA Hydrolase Desaturase Stearoyl-CoA Stearoyl-CoA Desaturase Stearoyl CoA Desaturase Desaturase Stearyl-CoA Stearyl-CoA Desaturase Stearyl CoA Desaturase Desaturase Stearate Stearate Desaturase Desaturase delta-9 delta-9 Desaturase 6.930797158643
13338 SU 6656 330161-87-0 ≥95% 2009-08-04 23.932662983425 su-6656 inhibitors Src kinases Src Yes Lyn Fyn cells growth development nervous system fibrosis cancers inhibits inhibition CNS SU6656 23.932662983425
10007565 Tetradecyl Phosphonate 4671-75-4 >98% 2005-10-17 49.791160220994 tetradecyl-phosphonate pan-antagonists LPA receptors lysophosphatic acids lipids signalling molecules hydrolysis lysophospholipase D autotoxin signals GPCRs G-protein coupled LPA1/EDG-2 LPA2/EDG-4 LPA3/EDG-7 LPA4/GPR23 activates activation PPAR.gamma. peroxisomes proliferator-activated inhibits inhibition LPA-induced calcium mobilization activates reporter 49.791160220994
10398 TG003 300801-52-9 ≥95% 2011-08-17 3.845303867404 tg003 inhibitors CDC kinasesTG 003 TG-003 TG3 TG-3 TG 3 Cdc2-like kinases Clks serine/arginine-rich proteins splicing RNA Clk1/Sty Clk4 serine rich pre-mRNA Xenopus arginine SR mRNA Sty Clk1 CLk2 Clk3 Clk4 benzothiazole inhibition inhibits inhibitor SF2 SF2/ASF ASF 3.845303867404
10522 Thapsigargin 67526-95-8 ≥97% 2011-09-23 50.668617447869 thapsigargin calcium, ATPases, sarco/endoplasmic calcium ATPases SERCAs cells signaling activation histamine cancers tumorigenesis inflammation reticula sarcoplasmic endoplasmic 50.668617447869
13237 Thiamet G Exclusive 1009816-48-1 ≥97% ✓ 2009-06-25 43.255745856354 thiamet-g inhibitors inhibits inhibitions tau alzheimers disease O-GlcNAc OGlcNAc O-GlcNAcase OGlcNAcase O-GlcNAcylation OGlcNAcylation Thiamet-G 43.255745856354
700240 Total Phosphatidic Acid Assay Kit - 2009-08-24 69.939443567482 total-phosphatidic-acid-assay-kit PA Assay Kit assays kits measures fluorescence-based cells cellular phospholipids phosphatidate membranes storage de novo synthesis phospholipases PLD PLA hydrolysis phosphodiesters phosphatidylcholines PC phosphorylation diacylglycerol DAG DAGK lysophosphatidic LPA lysoPA-acyltransferase LPAAT phosphates phosphohydrolases LPPs intracellular signal transduction mammalian rapamycin mTOR signaling cycle progression growth disregulation human diseases cancers bacterial FKBP12 Raf-1 kinases sphingosines cAMP Adenosines 3',5' cyclic mononucleotides phosphodiesterases 4A1 translocation proteins PKC tyrosines SHP-1 guanine nucleotides Son of sevenless glycerol-3-phosphate oxidized oxidases hydrogen peroxides H2O2 peroxidases ADHP 10-acetyl-3,7-dihydroxyphenoxazines resorufin 69.939443567482
10855 TRAF2 Monoclonal Antibody (Clone 33A1293) - 2011-05-06 0E-12 traf2-monoclonal-antibody-clone-33a1293 TRAF 2 TRAF-2 WBs western blots TNF tumors necrosis antibodies signal transduction proteins blotting immunoblotting 0E-12
10872 TRAF3 Polyclonal Antibody - 2011-05-26 1.407447513812 traf3-polyclonal-antibody TRAF 3 TRAF-3 WBs western blots TNF tumors necrosis antibodies signal transduction proteins blotting immunoblotting 1.407447513812
10873 TRAF5 Monoclonal Antibody (Clone 55A219) - 2011-05-26 1.407447513812 traf5-monoclonal-antibody-clone-55a219 TRAF 5 TRAF-5 WBs western blots TNF tumors necrosis antibodies signal transduction proteins blotting immunoblotting 1.407447513812
10894 TRAF6BP Polyclonal Antibody - 2011-05-26 1.407447513812 traf6bp-polyclonal-antibody TRAF6 Binding Protein; TAX1-binding protein; T6BP; TAX1BP1 TRAF 6BP TRAF-6BP WBs western blots TNF tumors necrosis antibodies signal transduction proteins blotting immunoblotting 1.407447513812
10874 TRAF6 Polyclonal Antibody - 2011-05-26 1.407447513812 traf6-polyclonal-antibody TNF Receptor-Associated Factor 6 TRAF 6 TRAF-6 WBs western blots TNF tumors necrosis antibodies signal transduction proteins blotting immunoblotting 1.407447513812
10010237 Triciribine 35943-35-2 ≥98% 2007-09-11 6.821546961326 triciribine Tricyclic Nucleoside; NSC 154020; API 2 Akt cancers inhibitors inhibition inhibits Akt-1 Akt1 Akt-2 Akt2 Akt-3 Akt3 PI3-kinase PI3kinase PI3K PI-3-kinase phosphorylation activation signalling pathway signaling 6.821546961326
70970 U-0126 109511-58-2 >98% 2007-11-20 25.999250197316 u-0126 U0126 MAPK MAP Kinases inhibitors inhibits inhibition MEK MEK1 MEK2 signal transduction ATP adenosine triphosphate U 0126 25.999250197316
10009152 Valinomycin 2001-95-8 >95% 2007-01-22 15.780239410681 valinomycin NSC 122023 Ionophore potassium ion antibiotic apoptosis cyclododecadepesipeptide Streptomyces efflux phosphatidylserine membrane translocation caspase-3 activation 15.780239410681
13671 Wortmannin-Rapamycin Conjugate - ≥98% 2010-05-11 9.973338789986 wortmannin-rapamycin-conjugate phosphoinositides 3-kinases PI3K mammalian targets mTOR cancers inhibitors inhibits inhibition complex 1 mTORC1 tumors bevacizumab VEGF colons A498 HT29 53123-88-9 sirolimus prodrug linkers links 19545-26-7 KY 12420 renal phosphatidyl inositols 9.973338789986
11179 WSP-1 New - ≥95% 2012-01-17 15.490112622184 wsp-1 Washington State Probe-1 hydrogen sulfide H2S fluorescent probes immunological immune neurological cardiovascular pulmonary mammals disulfide cells benzoithiolone fluorophore WSP1 WSP 1 15.490112622184
10008883 WST-1 Cell Proliferation Assay Kit - 2006-09-07 75.640332189474 wst-1-cell-proliferation-assay-kit assays cells proliferation induction inhibitors inhibition inhibits growth factors signaling signalling molecules cycles regulatory factors cytokines mitogens drugs microtiter plates in vitro enzymes enzymatic cleavage tertrazolium salts formazan cellular mitochondrial dehydrogenases screen kits measures measurements cancers cell-based assay cell based assay cba 75.640332189474
10010199 WST-8 Cell Proliferation Assay Kit - 2007-09-11 75.212933875886 wst-8-cell-proliferation-assay-kit assays cells proliferation induction inhibitors inhibition inhibits growth factors signaling signalling molecules cycles regulatory factors cytokines mitogens drugs microwell plates in vitro enzymes enzymatic cleavage tertrazolium salts formazan cellular mitochondrial dehydrogenases screen kits measures measurements special:quarterly specialdiscount:50 specialstart:2007-12-01 specialend:2008-02-29 cell-based assay cell based assay cba 75.212933875886
13604 WYE-354 New 1062169-56-5 ≥98% 2012-01-12 12.173137712297 wye-354 mTOR mTORC1 mTORC2 inhibitors inhibits inhibition PI3K cancers cells growth PTENs tumors rapamycin complex 1 2 G1 phosphatidylinositol 3-kinase α PI3Kα kinases 12.173137712297
13639 WZ811 55778-02-4 ≥95% 2010-03-22 44.403024861878 wz811 CXC chemokines receptors CXCR4 stromal cell-derived factor-1 SDF-1 CXCL12 hematopoietic stem cells chemotaxis lymphocytes growth metastasis cancers T cells HIV infection inhibitors antagonist cAMP Matrigel invasion breast cancer adenocarcinoma inhibition alpha-Aminotoluene alpha Aminotoluene Phenylmethylamine Benzylamines 44.403024861878
13596 XAV939 284028-89-3 ≥98% 2009-12-03 20.314585635359 xav939 Wnt cancers β-catenin APC axin GSK3 poly-ADP-ribosylation tankyrases TNKS1 TNKS2 inhibitors inhibition inhibits 20.314585635359
10010200 XTT Cell Proliferation Assay Kit - 2007-09-11 54.557532260927 xtt-cell-proliferation-assay-kit assays cells proliferation induction inhibitors inhibition inhibits growth factors signaling signalling molecules cycles regulatory factors cytokines mitogens drugs microtiter plates in vitro enzymes enzymatic cleavage tertrazolium salts formazan cellular mitochondrial dehydrogenases screen kits measures measurements special:quarterly specialdiscount:50 specialstart:2007-12-01 specialend:2008-02-29 cell-based assay cell based assay cba 54.557532260927
10005583 Y-27632 (hydrochloride) 129830-38-2 >98% 2007-11-29 134.186408839779 y-27632-hydrochloride Y27632 inhibitors inhibit inhibition Rho ROCK ROCK-II ROCKII PRK2 smooth muscle contraction cell adhesion signal transduction kinase phosphorylation HCl competative Y 27632 146986-50-7 134.186408839779
13246 YM-58483 223499-30-7 ≥98% 2009-11-16 5.369171270719 ym-58483 BTP 2 calcium channels leukocytes leukotrienes eicosanoids inflammation asthma allergy IL-2 IL-4 lymphocytes eosinophils NF-AT CRACs CysLTs interleukin-4 BTP2 BTP-2 CysLT 5.369171270719
13665 YS121 Exclusive 916482-17-2 ≥98% ✓ 2010-04-02 17.990220994475 ys121 Microsomal Prostaglandin E2 Synthase-1 mPGES-1 cyclooxygenase-2 COX-2 PGE2 inflammation fever pain 5-Lipoxygenase 5-LO leukotrienes LTs inhibitors LTB4 cyclooxygenase-1 COX-1 LTC4 LTD4 LTE4 inhibition Pyrimidines inhibits PGs YS 121 YS-121 17.990220994475
10010421 Zaprinast 37762-06-4 ≥98% 2008-09-18 6.124180478821 zaprinast 2-(o-Propoxyphenyl)-8-azapurin-6-one; M&B 22,948 sildenafil viagra phophodiesterase cGMP PDE5 GRP35 inhibitors inhibits inhibition M&B 22948 55122-20-8 6.124180478821
71800 (Z)-Guggulsterone 39025-23-5 ≥98% 2009-12-01 1.169042357274 -z-guggulsterone anti flammatory cancers FXR bile acids LDL cholesterol tumors IL-6 STAT3 VEGF Akt 1.169042357274
10010367 ZM 336372 208260-29-1 >98% 2008-01-09 3.659251632345 zm-336372 Raf-1 c-raf inhibitors inhibition inhibits cancers anti-cancer MEK 1/2 MAPK signals transductions proliferations cells cycles ERK1 ERK2 ERK1/2 ATP adenosine triphosphate signaling carcinoid tumor 3.659251632345
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