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Join us! · SLAS2012 1st Annual Conference & Exhibition · San Diego, California · February 4-8, 2012 · Booth 445

Research Area · Signal Transduction

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Item Number Product Sizes & Pricing CAS Purity Image Exclusive Introduction Date Mojo Plain Text Name Synonyms Keywords Interest
10008646 1,2-Dihexanoyl-sn-glycerol Exclusive 30403-47-5 ≥95% ✓ 2007-08-29 8.072651933702 1-2-dihexanoyl-sn-glycerol PKCs second messengers diacylglycerols DAG 1,2-dioctanoyl-sn-glycerols proteins kinases snglycerol 8.072651933702
10007863 1,2-Dioleoyl-rac-glycerol 2442-61-7 ≥95% 2010-11-10 1.812707182320 1-2-dioleoyl-rac-glycerol (±)-1,2-Diolein; rac-Glycerol 1,2-dioleate diacylglycerols DAGs proteins kinases C PKCs DGKs multisubstrates lipids MuLK 1,2-Di(cis-9-octadecenoyl)-rac-glycerol rac-1,2-dioleoylglycerol Diacylglycerols Diglycerides 1.812707182320
10008648 1,2-Dipalmitoyl-sn-glycerol 30334-71-5 ≥95% 2008-06-25 5.122375690608 1-2-dipalmitoyl-sn-glycerol NSC 269964; 1,2-DPG PKC proteins kinases C DAG activator 5.122375690608
13532 17-phenyl trinor Prostaglandin E2 ethyl amide Exclusive - ≥98% ✓ 2010-05-04 393.942559852670 17-phenyl-trinor-prostaglandin-e2-ethyl-amide 17-phenyl trinor PGE2 ethyl amide 17-phenyl trinor PGE2 agonists EP1 EP3 receptors EP4 smooth muscles contraction fertility prostaglandins PGs 393.942559852670
13812 17β-hydroxy Wortmannin Exclusive - ≥98% ✓ 2010-05-18 31.766271332106 17-hydroxy-wortmannin phosphoinositide 3-kinase PI3K mTOR inhibitors inhibits inhibition inhibitory cancers 17-hydroxywortmannins 17-hydroxy wortmannins hydroxywortmannins PI3-K HWT phosphatidylinositol 31.766271332106
10954 1-NA-PP1 New 221243-82-9 ≥98% 2011-09-30 66.915924653064 1-na-pp1 PP1 Analog; 1-Naphthyl-PP1 inhibitors inhibits inhibition kinases mutated analogs sensitive v-Src vSrc c-Fyn cFyn CDK2 c-Abl cAbl mammalian yeast 1NMPP1 1NA-PP1 cells permeable tyrosine cell-permeable AS Src-family Src I338G v-Src-AS1 66.915924653064
13330 1-NM-PP1 221244-14-0 ≥95% 2009-07-22 73.225039007554 1-nm-pp1 PP1 Analog II inhibitors inhibits inhibition kinases mutated analogs sensitive v-Src vSrc c-Fyn cFyn CDK2 CAMKII mammalian yeast 1NMPP1 73.225039007554
10007072 1-Palmitoyl-2-linoleoyl PE 26662-95-3 ≥98% 2005-12-20 10.404530386740 1-palmitoyl-2-linoleoyl-pe PLPE; Phosphatidyl Ethanolamine (1-palmitoyl, 2-linoleoyl) phosphoethanolamines phosphatidylethanolamines lipids biosynthesis lysophospholipases anandamides biochemical pathways fatty acids cellular membranes A2 D substrates sPLA2-IIA 10.404530386740
10008650 1-Stearoyl-2-Arachidonoyl-sn-Glycerol 65914-84-3 >95% 2008-04-04 5.494917127072 1-stearoyl-2-arachidonoyl-sn-glycerol SAG signal transduction PKCs DAGs .omega.6 PUFA RasGRP ERK MAPK fatty acids signalling signaling activators diacylglycerols 5.494917127072
10009872 1-Stearoyl-2-Arachidonoyl-sn-Glycerol-d8 Exclusive - ≥99% deuterated product ✓ 2008-12-04 4.793259668508 1-stearoyl-2-arachidonoyl-sn-glycerol-d8 SAG-d8 deuterium GC/MS internal isotopes standards ethanolamides GC-MS LC/MS LC-MS mass spectrometry deuterated 4.793259668508
10005707 (2S)-OMPT - >98% 2005-10-19 31.877513812154 -2s-ompt GPR lysophosphatidic acids lipids mediators receptors LPA1/Edg-2 LPA2/Edg-4 LPA3/Edg-7 LPA4/GPR23 agonists calcium mobilization Sf9 cells (2R)-OMPT release assays LPA3-transfected rat hepatoma Rh7777 31.877513812154
10727 3,5-dimethyl PIT-1 701947-53-7 ≥98% 2011-05-25 17.132179251074 3-5-dimethyl-pit-1 PIP3 PtdIns-(3,4,5)-P3 PH domain cancers inhibitors Akts PDK1 PTENs proteins binding inhibits inhibited inhibition DM-PIT-1 17.132179251074
10009804 3-PT-PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt) - ≥98% 2009-03-20 7.450639305446 3-pt-ptdins-3-4-5-p3-1-2-dioctanoyl-sodium-salt 3-Phosphorothioate-Phosphatidylinositol-4,5-diphosphate C-8 (sodium salt) 3-PT-PtdIns(3,4,5)-P3 PtdIns(3,4,5)-P3 PTEN PIP PIP(3,4,5) cells signaling PI3 kinases cancers phosphatidyl inositols phosphates membrane phospholipids signalling sodium transport 7.450639305446
10010375 5-Iodotubercidin 24386-93-4 ≥95% 2008-01-24 34.945653775322 5-iodotubercidin Itu; NSC 113939 adensosine glycogen hepatocytes phosphorylase .alpha. glycogen synthase .alpha. kinases protein kinase A casein kinases II casein kinases I protein kinase C phosphorylase kinases EFK2 MAPK1 cell proliferations fatty acid oxidations lipogenesis acetyl-CoA carboxylase 34.945653775322
10009856 7-AAD Cell Viability Assay Kit - 2008-10-29 27.291877302025 7-aad-cell-viability-assay-kit 7-Amino Actinomycin D Cell Viability Kit kits 7AAD measurement cells fixation blocking cytoxicity effects environmental toxins drug fluorescence fluorescent cell-based assays cell based assay cba 27.291877302025
9000530 7(Z)-Pentacosene Exclusive 63623-49-4 ≥98% ✓ 2009-12-03 12.561569060773 7-z-pentacosene pheromones fruits flies Drosophilia copulation hydrocarbon 7-pentacosene (Z)-7-pentacosene cis-7-pentacosene 7-cis-pentacosene 12.561569060773
9000313 7(Z)-Tricosene Exclusive 52078-42-9 ≥98% ✓ 2009-03-15 17.434143646408 7-z-tricosene fruits fly flies pheromone drosophila bombus hydrocarbon 17.434143646408
10010109 8-DY547-cGMP - ≥98% 2008-10-23 715.954972375691 8-dy547-cgmp CNGA2 channels activators fluorescences cyclic nucleotides 715.954972375691
11016 A-23187 New 52665-69-7 ≥98% 2011-10-25 9.653485907087 a-23187 Calcimycin calcium cells activations ionophore signaling apoptosis antibiotic A23187 A 23187 37259-87-6 37263-57-3 51257-80-8 51310-65-7 53095-21-9 9.653485907087
13653 ABT-869 796967-16-3 ≥98% 2010-12-09 33.206842899529 abt-869 Linifanib inhibitors RTK tyrosine kinases VEGF PDGF cancers KDR Flt1 Flt3 Flt4 CSF-1R KIT acute myeloid leukemia antiproliferative anti-proliferative ABT 869 ABT869 Indazoles 33.206842899529
13297 AG-126 118409-62-4 ≥95% 2009-07-14 6.235295974743 ag-126 Tyrphostin AG-126 tyrphostins proteins tyrosine inhibitors inhibits inhibition cells growth epidermal growth factors receptors kinase GFRK EGFs EGFRK PDGF PDGFRK platelet-derived platelet derived phosphorylation ERK1 p44 ERK2 p42 TNF-α TNFα TNF α NF-κB NFκB NF κB COX-2 COX2 iNOS inflammation 6.235295974743
10010568 AG-370 134036-53-6 >95% (cis/trans mixture) 2009-01-09 1.236625230202 ag-370 NSC 651712 PTK inhibitor tyrphostin tyrosine PDGF receptor kinase EGF receptor antiproliferative 1.236625230202
10010243 AG-825 149092-50-2 >98% 2008-01-24 4.800880031570 ag-825 Tyrphostin AG-825 Her-2 Her-2/neu erbB tyrosine kinases EGF EGFR cancers anti-cancer prostate breast signal transduction inhibitors inhibition inhibits AG825 AG 825 4.800880031570
10793 AG-879 148741-30-4 ≥95% 2011-05-06 1.826541436464 ag-879 Tyrphostin AG-879 PTKs inhibitors tyrphostins tyrosine kinases antiproliferative NGF TrkA ErbB2 FLK-1 AG879 AG 879 inhibited inhibition 1.826541436464
13735 Akt2/3 Polyclonal Antibody - 2010-01-12 0.689423835832 akt2-3-polyclonal-antibody Akt-2 Akt 2 PKB proteins kinase B serine threonine signaling PI3-kinase cancers Western blots blotting immunoblotting WB Akt-3 Akt 3 2-3 0.689423835832
13734 Akt2 Monoclonal Antibody (Clone 95C567.1.2) - 2010-01-12 0.689423835832 akt2-monoclonal-antibody-clone-95c567-1-2 Akt-2 Akt 2 PKB proteins kinase B serine threonine signaling PI#-kinase cancers Western blots blotting immunoblotting WB 0.689423835832
10010079 Akt (human recombinant) Western Ready Control Exclusive - ✓ 2008-08-26 6.029497237568 akt-human-recombinant-western-ready-control Protein Kinase B; PKB; AKT1 western blots proteins antibodies antiserum antisera WB kinases serine threonine hexahistidine his-tag his-tagged N-terminal immunoblotting blotting 6.029497237568
10007466 Arachidonic Acid-biotin - >98% 2005-11-30 31.946850828728 arachidonic-acid-biotin fatty acids PUFAs polyunsaturated biotinylated affinity probes binding proteins cellular cells esterified membranes phospholipids regulated pathways substrates biosynthesis eicosanoids messengers receptor-stimulated release metabolisms re-uptake signalling inflammation detection detected complexes elucidations transports FABPs biotins biotinylated 31.946850828728
13495 ARAP2 Polyclonal Antibody - 2009-09-03 0.405184870378 arap2-polyclonal-antibody Centaurin-δ-1 antibodies proteins A chromatography WB western blots immunoblotting IHC immunohistochemistry blotting 0.405184870378
13496 AROS Polyclonal Antibody (aa 1-50) - 2009-09-03 0.885635359116 aros-polyclonal-antibody-aa-1-50 WB western blots immunoblotting protein nucleolar RPS19 cDNA chromosome 22q13.1 antibodies blotting 0.885635359116
13498 ARRB2 Polyclonal Antibody - 2009-09-22 13.051933701657 arrb2-polyclonal-antibody β-Arrestin-2 WB IHC western blots blotting immunoblotting antibodies immunohistochemisty ARRB-2 βarrestin2 β-arrestin2 β arrestin 2 β2R receptors adrenergic 13.051933701657
13622 AS-041164 Exclusive 1146702-72-8 ≥98% ✓ 2010-01-25 11.629944751381 as-041164 phosphoinositides 3-kinases PI3K cells growth migration metabolism inhibitors inhibits PI3Kα PI3Kβ PI3Kγ PI3Kδ chemotaxis inflammation neutrophils AS041164 AS-041164 RANTES 11.629944751381
10009052 AS-252424 900515-16-4 >95% 2007-01-30 30.681124704024 as-252424 phosphoinositides 3-kinases PI-3 PI3-K Phosphatidylinositol inhibitors PI3K .gamma. inhibition inhibitory PtdIns AS252424 30.681124704024
10007707 AS-605240 648450-29-7 >98% 2007-06-13 28.390828729281 as-605240 phosphoinositide 3-kinases PI3-kinase PI3-K PI3K phosphoinositide phosphatidylinositols inibitors inflammation arthritis rheumatoid peritonitis neutrophils recruitment as605240 28.390828729281
9000980 AS-605240 (potassium salt) Exclusive - ≥98% ✓ 2011-03-25 21.879921073402 as-605240-potassium-salt phosphoinositides 3-kinases PI3-kinases PI3-K PI3K phosphatidylinositols inhibitors inflammation arthritis rheumatoid peritonitis neutrophils recruitment as605240 as 605240 PIs salts solubility soluble 21.879921073402
10009410 ATF2 (Phospho-Ser490,498) Polyclonal Antibody - 2006-11-28 1.087707182320 atf2-phospho-ser490-498-polyclonal-antibody Activating Transcription Factor 2 wb western blotting blots ihc immunohistochemistry antibodies activating transcriptional factors CRE-BP1 AP-1 DNA response elements ATF/CREB leucine zipper proteins regulating regulation genes cytokines cells cycles controls apoptosis death cellular stress inflammatory UV irradiation activity phosphorylation serines brains substrates neuronal neurons growth differentiation human depression phospho-specific immunoblotting 1.087707182320
600140 Autophagy/Cytotoxicity Dual Staining Kit - 2009-07-14 78.680428176795 autophagy-cytotoxicity-dual-staining-kit assays kits measuring measurement MDC cell-based autophagy cells cytotoxicity staining autofluorescent autofluorescence substances multilamellar body bodies ions trapping mechanisms membranes lipids probes autophagic vacuoles cultured degradation digestion intracellular lysosomes organelles misfolded proteins microorganisms cytoplasms double membranes autophagosomes autolysosomes homeostasis dysregulation cancers infections aging degenerative diseases stress death apoptosis 78.680428176795
10011336 Avenanthramide-C methyl ester Exclusive 955382-52-2 ≥95% ✓ 2009-06-18 67.141074836765 avenanthramide-c-methyl-ester Inhibitors NF-κB IL-6 IL-8 MCP-1 IκB inhibits inhibition Interleukins 67.141074836765
13823 AX 048 Exclusive 873079-69-7 ≥98% ✓ 2010-09-15 9.311602209945 ax-048 Inflammation antihyperalgesia cPLA2 phospholipases inhibitors inhibition inhibits AX048 AX-048 signaling signalling group IVA PLA2 cannabinoids cbs synthetic Acids Octanoic Octanoic Acids 9.311602209945
10011131 BAY-41-8543 Exclusive 256498-66-5 ≥98% ✓ 2009-11-16 19.824977619194 bay-41-8543 soluble guanylate cyclase sGC nitric oxide NO GTP cyclic GMP cGMP agonist stimulator platelet aggregation blood pressure bleeding time thrombosis pulmonary hypertension BAY 41-8543 BAY 41 8543 19.824977619194
10011135 BAY-60-7550 439083-90-6 ≥95% 2009-03-13 62.147452616635 bay-60-7550 inhibitors inhibits inhibition cyclic nucleotides cGMP cAMP cells signalling signaling PDE2 memory memories phosphodiesterase 62.147452616635
13123 BIO 667463-62-9 ≥98% 2009-06-09 29.315680562530 bio GSK 3 IX; MLS 2052 GSK-3α GSK-3β inhibitors Cdk cells cycle wnt ESCs differentiation embryonic stem GSK-3a/b GSK3a/b 29.315680562530
10005836 bis(7)-Tacrine 224445-12-9 >98% 2005-04-15 4.727513812155 bis-7-tacrine 1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydro-acridine dimeric congeners amino acridines inhibits inhibitors inhibition acetylcholinesterases Alzheimer's disease hydrogen peroxides apoptosis pheochromocytoma cells neurochemistry neuroscience 4.727513812155
13298 Bisindolylmaleimide I 133052-90-1 ≥95% 2009-08-28 13.694917127072 bisindolylmaleimide-i Gö 6850; GF 109203X; BIM 634199-82-9 682340-45-0 inhibitors inhibits inhibitions PCK GSK-3 GSK3 staurosporine 5-HT3 receptors 5HT3 Go 6850 13.694917127072
13299 Bisindolylmaleimide IV 119139-23-0 ≥98% 2009-07-29 9.348204419889 bisindolylmaleimide-iv Arcyriarubin A PKC PKA staurosporine inhibitors 634199-73-8 9.348204419889
13186 (±)-Blebbistatin 674289-55-5 ≥98% 2009-06-09 54.049226519337 -blebbistatin inhibitors muscles myosin ATPase smooth bleb apoptosis cells migration chemotaxis cytokinesis division growth UV lights 54.049226519337
10681 C-16 Ceramide 24696-26-2 ≥98% 2011-03-08 4.184799723756 c-16-ceramide Palmitoyl Ceramide sphingomyelins apoptosis ceramides lipids membranes second messengers C16 ceramides longevity assurance homologs 6/LASS6 Ceramides C 16 4.184799723756
10724 C-20 Ceramide 7344-02-7 ≥98% 2011-03-08 3.661975138121 c-20-ceramide sphingomyelins apoptosis differentiation brains C20-ceramide C20:0 ceramides 20:0 synthesis 1 2 synthases 3.661975138121
10007518 Capsazepine 138977-28-3 >98% 2006-03-29 8.653471454879 capsazepine vanilloid receptors 1 VR1 transient potential TRP endogenous stimuli tissues injury inflammation pain antagonists capsaicin Ca2+ neonatal rats dorsal root ganglias Chinese hamsters ovary ovaries cells 8.653471454879
13702 Cav1.2 Calcium Channel Monoclonal Antibody (Clone S57-46) - 2009-11-05 1.922651933701 cav1-2-calcium-channel-monoclonal-antibody-clone-s57-46 antibodies western blotting blots immunoblotting WB immunohistochemistry IHC immunocytochemistry ICC channels ions fusion proteins gated voltage-gated ligand-gated voltage ligand 1.922651933701
13703 Cav1.3 Calcium Channel Monoclonal Antibody (Clone S38-8) - 2009-11-05 0.640883977900 cav1-3-calcium-channel-monoclonal-antibody-clone-s38-8 antibodies channels ions fusion proteins CACNAID western blots blotting immunoblotting WB immunohistochemistry IHC immunocytochemistry ICC gated voltage-gated ligand-gated voltage ligand 0.640883977900
13700 Cavβ1 Calcium Channel Monoclonal Antibody (Clone S7-18) - 2009-10-24 0.640883977900 cav-1-calcium-channel-monoclonal-antibody-clone-s7-18 antibodies western blotting immunoblotting WB IHC ICC IF immunohistochemistry immunocytochemistry immunofluorescence perox ions channels membrane proteins voltage ligands gated 0.640883977900
13701 Cavβ4 Calcium Channel Monoclonal Antibody (Clone S10-7) - 2009-11-05 0.640883977900 cav-4-calcium-channel-monoclonal-antibody-clone-s10-7 western blots blotting immunoblotting WB immunohistochemistry IHC immunocytochemistry ICC ions channels antibodies epilepsy IGE JME subunits gated voltage-gated ligand-gated ligand voltage 0.640883977900
10009078 CAY10505 328960-84-5 ≥98% 2009-11-04 8.344267955801 cay10505 phosphoinositide 3-kinase immunity autoimmune inflammation PI3Kγ PI3Kα PI3Kβ PI3Kδ casein kinases 2 CK2 phosphorylation PKB/Akt macrophages neutrophil recruitment cancer PI3s T2Ds PI3Ks PI3K.gamma. PI3Kg 8.344267955801
10010043 CAY10561 Exclusive 933786-58-4 >98% ✓ 2008-03-06 29.675248618784 cay10561 Pyrazolylpyrrole ERK Inhibitor MEK Ras Raf ERK2 proliferation cell cycles cancers apoptosis inhibition inhibit inhibitors 29.675248618784
10010233 CAY10567 32387-96-5 >98% 2008-05-06 3.416574585635 cay10567 BML-257 Akt1 inhibitors inhibits inhibition translocations HCV hepatitis signal transduction signaling signalling 3.416574585635
10010400 CAY10571 152121-46-5 >95% 2008-08-11 22.163977900553 cay10571 MAPK signal transduction p38 kinases heat shock cytokines inflammation immuno response CSAID CSBP UL-1 IL1 5-LO 5LO 22.163977900553
10011247 CAY10574 140651-18-9 >95% 2008-09-04 12.328154696132 cay10574 CDK2 cyclin E CDK9 inhibitors inhibits inhibition anticancer cell cycle CAN508 12.328154696132
10011248 CAY10575 916985-21-2 ≥95% 2008-09-03 26.612367797948 cay10575 IKKε IKK-ε IKK-e IKKe NFkB inflammation immune response cytokine kinase inhibitors inhibits inhibition NF-κB 26.612367797948
10011256 CAY10577 300675-28-9 ≥95% 2008-09-02 0.867403314917 cay10577 inhibitors inhibits inhibition CK2 kinase cell signaling apoptosis cancers 0.867403314917
10011264 CAY10578 19231-60-8 ≥95% 2008-08-26 0.867403314917 cay10578 inhibitors inhibits inhibition kinase cell signaling CK2 apoptosis cancers isoindolineacetic acids 0.867403314917
13206 CAY10593 Exclusive - ≥95% ✓ 2009-09-03 20.268552486188 cay10593 VU0155069 inhibitors inhibits inhibitions phospholipases D PLD PLD1 PLD2 phosphatidic acids PAs chemotaxis cells migration cancers breast lines tumors trans well assays 1130067-06-9 20.268552486188
13207 CAY10594 Exclusive 1130067-34-3 ≥98% ✓ 2009-06-23 20.392839779005 cay10594 Phospholipase D PLDs PLD1 PLD2 phosphatidic acid PA inhibitors chemotaxis cells migration cancers breast cancer inhibition inhibited 20.392839779005
13281 CAY10598 Exclusive 346673-06-1 ≥98% ✓ 2010-05-07 68.911458563535 cay10598 Prostaglandins E2 PGE2 receptors EP4 bone formation cancers atherosclerosis agonists EP1 EP2 EP3 DP FP IP TP neuroprotection renal dysfunction inflammation neuro-protection 68.911458563535
13358 CAY10608 Exclusive 457897-92-6 ≥98% ✓ 2010-04-29 0.652624309392 cay10608 N-Methyl-D-aspartate NMDA receptors antagonists glutamate glycine propanolamine NR2B subunit AMPA kainate neuroprotection neurochemistry antagonizes potently selectively non-competitively 0.652624309392
13687 CAY10622 Exclusive 1038549-25-5 ≥98% ✓ 2010-10-18 6.251952117863 cay10622 Rho kinases ROCK-I ROCK-II inhibitors inhibits inhibition 6.251952117863
13838 CAY10626 Exclusive 1202884-94-3 ≥98% ✓ 2010-08-23 21.325724711820 cay10626 PI3Kα mTOR cancers signal transduction inhibitors inhibits inhibition phosphatidylinositol 3-kinase PtdIns PIs 21.325724711820
10743 CAY10650 Exclusive 1233706-88-1 ≥98% ✓ 2011-06-14 23.657458563536 cay10650 cPLA2α cPLA2 inhibitors inflammation anti-inflammatory dermatitis metabolite phospholipase cytosolic prostaglandins PGs leukotrienes synthesis 10662 CAY-10650 CAY10641 CAY-10641 23.657458563536
10787 CCG-100602 New 1207113-88-9 ≥98% 2011-11-22 23.018262737876 ccg-100602 Rho signaling signal transduction cancers inhibitors SRF serum response factors transcription CCG-1423 megakaryoblastic leukemia 1 MKL1 prostate analogs PC-3 CCG100602 CCG 100602 CCG1423 CCG 1423 cells DNA binding RHOA/C-mediated MKL-1 23.018262737876
10010350 CCG-1423 285986-88-1 >98% 2007-09-20 13.134134876786 ccg-1423 Rho signaling transduction cancers proliferations anti-proliferation anti-tumor serum response factor GTPase inhibits inhibitors inhibition signalling 13.134134876786
13322 CGP 57380 522629-08-9 ≥95% 2009-08-28 31.493305709024 cgp-57380 MNK1 Inhibitor inhibitors inhibits inhibitions MAPKs MAP kinases interacting interacting-kinase 1 MNK1 p38 JNK1 ERK1/2 PKC Src-like phosphorylation elF4E TNF-a TNF-α TNFα TNFa arsenite anisomycin PMA fetal calf serum 293 cells RAW264.7 toll-like receptors TLR2 HKLM TLR4 LPS TLR6/2 FSL TLR7 imiquimod TLR9 CpG DNA CGP57380 CGP-57380 31.493305709024
11314 Chelerythrine chloride New 3895-92-9 ≥98% 2012-01-31 105.204434622468 chelerythrine-chloride NSC 646662; Broussonpapyrine chloride 6004-02-0 84282-43-9 chelerythrinium inhibitors inhibits inhibition PKC apoptosis cells signaling BclXL Bcl-2 cancers tumors p38 MAP kinases proteins JUNK 105.204434622468
13686 Chidamide 743420-02-2 ≥98% 2010-08-10 79.066856967464 chidamide HDACs histones deacetylase H3 acetylation colons cancers cells inhibitors inhibits inhibiton LoVo HT-29 HT29 HT 29 cycle arrest chidamides oncogenic signalling signaling kinases Benzamides 79.066856967464
13122 CHIR99021 252917-06-9 ≥98% 2011-02-18 78.808571428571 chir99021 CT 99021 GSK-3α GSK-3β inhibitors glucose metabolism insulin diabetes Wnt stem cells mice mouse CHIR-99021 CT-99021 CHIR 99021 CT99021 pyridines glucogen synthesis CHO-IR self-renewal 78.808571428571
581001 Cyclic AMP EIA Kit - 698.206362869021 cyclic-amp-eia-kit Adenosine 3',5'-cyclic monophosphate EIA Kit; cAMP EIA Kit; Adenosine 3',5'-cyclic mononucleotide EIA Kit; Cyclic AMP ELISA Kit solid plates cAMP adenosine measures kits eias enzyme immunoassays ELISAs second messengers neurochemistry neuroscience endocrinology assays 698.206362869021
581002 Cyclic AMP EIA Kit (without Acetic Anhydride) - 566.273107734807 cyclic-amp-eia-kit-without-acetic-anhydride cAMP EIA Kit (without Acetic Anhydride); Adenosine 3',5'-cyclic monophosphate EIA Kit (without Acetic Anhydride); Adenosine 3',5'-cyclic mononucleotide EIA Kit (without Acetic Anhydride); Cyclic AMP ELISA Kit (without Acetic Anhydride) solid plates cAMP adenosine measures kits eias enzyme immunoassays ELISAs second messengers neurochemistry neuroscience endocrinology assays 566.273107734807
13305 D 4476 301836-43-1 ≥98% 2009-07-29 35.262596685083 d-4476 Casein Kinase I Inhibitor inhibitors inhibits inhibition casein kinases 1 CK1 Ck1δ TGF-β TGFβ type-1 receptors ALK5 PKD1 p38α MAPK kinases phosphorylation FOXO1a RhoB p53 Smad3 D4476 35.262596685083
13197 DAPT 208255-80-5 ≥95% 2010-09-16 14.760055248618 dapt GSI-IX amyloids precursors proteins APP Notch beta amyloid Aβ Alzheimer’s disease inhibitors inhibits inhibition γ-secretase Aβ42 cells signaling signals differentiation GSIIX GSI IX Dipeptides 14.760055248618
13382 DAz-2 1176905-54-6 ≥98% 2009-11-05 15.127513812155 daz-2 DCP-N3 Daz1 Daz-1 Daz 1 sulfenic acids click chemistry ROS oxidative stress cysteine oxidation LC-MS/MS analysis standinger DCPN3 DCP N3 azoospermia protein 2 genes redox sensitive cysteine ROS oxidative modification stress signaling cells hydrogen peroxide alkyl hydroperoxides peroxynitrite adducts dimedone biotin fluorophores labels labeling lysis staudinger ligation LC-MS MS LC analysis sulphenic acids 15.127513812155
10010706 (−)-Deguelin 522-17-8 ≥98% 2008-09-18 16.982430939227 -deguelin (-)-cis-Deguelin rotenoids flavonids cancers antiproliferative chemoprevention parkinsons diseases Akt PKB PI3K COX-2 COX2 apoptosis PI3-K 16.982430939227
10007945 D-erythro-Sphinganine 764-22-7 ≥98% 2010-08-10 20.946263184329 d-erythro-sphinganine D-erythro-Dihydrosphingosine ceramide sphingosine sphingosine kinases sphinganine-1-phosphates mycotoxins fumonisins cancers protein kinase C PKC spingosine-1-phosphates cell signaling octadecasphinganine Dihydro-C18-sphingosine SPC 102860 SPC102860 signalling SPC-102860 20.946263184329
10007903 D-erythro-Sphingosine C-20 6918-49-6 ≥98% 2008-11-21 5.605718232044 d-erythro-sphingosine-c-20 sphingosines sphingolipids ceramides C-18 C18 C20 gangliosides brain development neurodegenerations 5.605718232044
11015 Dexamethasone New 50-02-2 ≥98% 2011-10-25 64.769483804571 dexamethasone MK 125; NSC 34521 steroids hormones glucocorticoid agonist receptors inflammation genes expression anti-inflammatory antiinflammatory anti inflammatory 8054-59-9 137098-19-2 906362-70-7 906422-84-2 1050677-47-8 adexone aeroseb-Dex aphtasolon aphthasolone azium calonat corsone cortisumman decacort decaderm decadron A decalix decasone dekacort dekort delipos deltafluorene dergramin deronil desadrene desameton deseronil dexa-cortidelt dexa-mamallet dexa-scheroson dexa-sine dexacort dexacortal dexacortin dexadeltone dexafarma dexalona dexaltin dexameth dexamethasone alcohol dexamonozon dexapolcort dexapos dexaprol dexason dexasone dexinoral dexmethsone dexone dexonium dextelan dinomon diodex etacortilen fluormone fluorocort gammacorten gentalipos HL-dex hexadecadrol hexadrol isopto-dex lokalison F loverine luxazone MK-125 MK125 maxidex millicorten NSC-34521 NSC34521 oradexon pet-derm III posurdex prednisolon F prednisolone superprednol surodex visumetazone 64.769483804571
10012577 Diallyl Trisulfide 2050-87-5 ≥98% 2009-04-07 21.778752608962 diallyl-trisulfide DATS; NSC 651936 garlic hydrogen sulfides H2S cancers tumors smooth muscle cholesterol atherosclerosis donors supresses colon synthesis genes expression adenocarcinomas HCT-15 cells PC-3 xenografts 21.778752608962
11095 DL-Palmitoylcarnitine chloride New 6865-14-1 ≥95% 2011-12-07 35.555555555556 dl-palmitoylcarnitine-chloride NSC 628323; Palmitoyl-DL-carnitine chloride carnitine acylcarnitine fatty acids oxidation mitochondria calcium tight junctions permeability cells calcium endothelial epithelial 6819-24-5 52234-80-7 68960-79-2 127719-10-2 carnitine palmitoyl intracellular extracellular oxidation energy mobilization junctions viability permeability resistance 35.555555555556
10008448 D-myo-Inositol-1,2,3,4-tetraphosphate (sodium salt) - ≥98% 2007-06-22 8.503609576426 d-myo-inositol-1-2-3-4-tetraphosphate-sodium-salt Ins(1,2,3,4)-P4 (sodium salt); 1,2,3,4-IP4 (sodium salt) phosphates IP3 transduction InsPs phosphatidylinositols phospholipases C Pleckstrin homology PH domains signalling signaling cells 8.503609576426
10008449 D-myo-Inositol-1,2,3,5-tetraphosphate (sodium salt) - ≥98% 2007-06-27 7.266284530387 d-myo-inositol-1-2-3-5-tetraphosphate-sodium-salt Ins(1,2,3,5)-P4 (sodium salt); 1,2,3,5-IP4 (sodium salt) inositols phosphates IP3 transduction InsP phosphatidylinositol phospholipase C Pleckstrin signaling signalling cells homology PH domains 7.266284530387
10008450 D-myo-Inositol-1,2,3,6-tetraphosphate (sodium salt) - ≥98% 2007-06-22 6.989765193370 d-myo-inositol-1-2-3-6-tetraphosphate-sodium-salt Ins(1,2,3,6)-P4 (sodium salt); 1,2,3,6-IP4 (sodium salt) inositols phosphates IP3 transduction InsP phosphatidylinositol phospholipases C Pleckstrin homology PH domains signalling signaling cells 6.989765193370
10008452 D-myo-Inositol-1,2,4,5,6-pentaphosphate (sodium salt) - ≥98% 2007-06-08 5.150945923321 d-myo-inositol-1-2-4-5-6-pentaphosphate-sodium-salt 1,2,4,5,6-IP5 (sodium salt); Ins(1,2,4,5,6)P5 (sodium salt) IP3 inositols phosphate transduction InsP phosphitidylinositol phospholipase C PLC InsP6 kinase signaling signalling cells 5.150945923321
10008451 D-myo-Inositol-1,2,4,5-tetraphosphate (sodium salt) - ≥98% 2007-06-22 14.030372928176 d-myo-inositol-1-2-4-5-tetraphosphate-sodium-salt 1,2,4,5-IP4 (sodium salt); Ins(1,2,4,5)P4 (sodium salt) phosphates IP3 transduction InsPs phosphatidylinositols phospholipases C Pleckstrin homology PH domains signalling signaling cells 14.030372928176
10008444 D-myo-Inositol-1,2,5,6-tetraphosphate (sodium salt) - ≥98% 2007-06-06 9.244461325966 d-myo-inositol-1-2-5-6-tetraphosphate-sodium-salt 1,2,5,6-IP4 (sodium salt); Ins(1,2,5,6)P4 (sodium salt) inositol phosphates IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC Grp-1 Pleckstrin homology PH domain signalling signaling cells 9.244461325966
10007780 D-myo-Inositol-1,2,6-triphosphate (sodium salt) - ≥98% 2006-01-13 6.554868017188 d-myo-inositol-1-2-6-triphosphate-sodium-salt 1,2,6-IP3 (sodium salt); Ins(1,2,6)P3 (sodium salt) phosphates IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels D/L racemic Xenopus oocytes 6.554868017188
10008439 D-myo-Inositol-1,2-diphosphate (sodium salt) 208584-51-4 ≥98% 2008-01-17 6.053970007892 d-myo-inositol-1-2-diphosphate-sodium-salt 1,2-IP2 (sodium salt); Ins(1,2)P2 (sodium salt) inositols phosphates IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC signaling signalling PtdIns initiating Ca2+ calcium release phosphoinositols 6.053970007892
10009851 D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) - >98% 2007-06-04 8.561325966850 d-myo-inositol-1-3-4-5-6-pentaphosphate-ammonium-salt 1,2,4,5,6-IP5 (sodium salt); Ins(,1,3,4,5,6)P5 inositols phosphate IP5 signal transduction InsP phosphitidylinositol phospholipase C PLC phosphioinositide 3-kinase PI3-K Akt cancer angiogenesis PKB protein kinase B 8.561325966850
10007784 D-myo-Inositol-1,3,4,5,6-pentaphosphate (sodium salt) - ≥98% 2006-01-13 18.509683047397 d-myo-inositol-1-3-4-5-6-pentaphosphate-sodium-salt 1,3,4,5,6-IP5 (sodium salt); Ins(1,3,4,5,6)P5 (sodium salt) phosphoinositides 3-kinases PI3-K/Akt phosphates IP3 signals transductions cells growh proliferation anticancers agents isomers InsP phosphitidylinositols phospholipases messengers cellular PKB apoptosis ovarian lung breast antiangiogenic in vitro capillary tubes HUVEC antitumor xenografts nude mice PH domains Grp1 18.509683047397
60980 D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt) 210488-61-2 ≥98% 29.201232615735 d-myo-inositol-1-3-4-5-tetraphosphate-sodium-salt Ins(1,3,4,5)-P4 (sodium salt); 1,3,4,5-IP4 (sodium salt) IP4 inositols tetraphosphates salts phosphorylation 1,4,5-triphosphate-3-kinase intracellular calcium InsPs 29.201232615735
10008442 D-myo-Inositol-1,3,4,6-tetraphosphate (ammonium salt) 142507-74-2 ≥95% 2008-12-04 9.577559852670 d-myo-inositol-1-3-4-6-tetraphosphate-ammonium-salt 1,3,4,6-IP (ammonium salt); Ins(1,3,4,6)P4 (ammonium salt) inositol myo-inositol inositol phosphate second messenger inositol-1,2,3,4,5,6-hexakisphosphate phytic acid signal transduction 9.577559852670
10007781 D-myo-Inositol-1,3,5-triphosphate (sodium salt) - ≥98% 2006-01-11 4.871147943523 d-myo-inositol-1-3-5-triphosphate-sodium-salt 1,3,5-IP3 (sodium salt); Ins(1,3,5)P3 (sodium salt) phosphates IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels meso compounds Xenopus oocytes 4.871147943523
10008443 D-myo-Inositol-1,3-diphosphate (sodium salt) 208584-52-5 ≥98% 2006-12-21 8.265648358790 d-myo-inositol-1-3-diphosphate-sodium-salt Ins(1,3)-P2 (sodium salt); 1,3-IP2 (sodium salt) phosphates IP2 signals transductions InsP phosphatidyls inositols messengers cellular phospholipases PLC ER endoplasmic reticulum calcium Ca2+ dephosphorylation 8.265648358790
10007783 D-myo-Inositol-1,4,5,6-tetraphosphate (sodium salt) - ≥98% 2006-01-13 16.782169763938 d-myo-inositol-1-4-5-6-tetraphosphate-sodium-salt 1,4,5,6-IP4 (sodium salt); Ins(1,4,5,6)P4 (sodium salt) oligophosphates isomers IP3 signals transductions InsP phosphatidylinositols phospholipases intestinal epithelial cells strains incubation times Salmonella epidermal growth factor EGF PI3-kinases cellular calcium Ca2+ Ca++ channels D/L racemic mixture Xenopus oocytes 16.782169763938
60960 D-myo-Inositol-1,4,5-triphosphate (potassium salt) 103476-24-0 ≥98% 11.972023736443 d-myo-inositol-1-4-5-triphosphate-potassium-salt Ins(1,4,5)-P3 (potassium salt); 1,4,5-IP3 (potassium salt) IP3 inositols triphosphates salts phosphorylation receptors messengers inositol-4,5-biphosphate hydrolysis intracellular calcium PLC phospholipases InsPs 11.972023736443
10008205 D-myo-Inositol-1,4,5-triphosphate (sodium salt) - ≥98% 2006-01-30 15.916087097822 d-myo-inositol-1-4-5-triphosphate-sodium-salt 1,4,5-IP3 (sodium salt); Ins(1,4,5)P3 (sodium salt) phosphates IP3 signals transductions InsP phosphitidylinositols Ins(1,4,5)P3 phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels analogs agonists rat hepatic receptors 15.916087097822
10008438 D-myo-Inositol-1,4-diphosphate (sodium salt) - ≥98% 2007-01-08 6.194748131297 d-myo-inositol-1-4-diphosphate-sodium-salt 1,4-IP2 (sodium salt); Ins(1,4)-P2 (sodium salt) phosphates IP2 signals transductions InsP phosphatidyls inositols messengers cellular phospholipases PLC ER endoplasmic reticulum calcium Ca2+ dephosphorylation signalling 6.194748131297
10008422 D-myo-Inositol-1,5,6-triphosphate (sodium salt) 120965-76-6 ≥98% 2009-08-04 16.850451197053 d-myo-inositol-1-5-6-triphosphate-sodium-salt Ins(1,5,6)-P3 (sodium salt); 1,5,6-IP3 (sodium salt) phosphates IP2 signal transduction cells cycling apoptosis differentiation motility InsP phosphatidyl inositol IP3 second messengers trisphosphates PtdIns phosphatidylinositol D-myos PIPS 16.850451197053
10008441 D-myo-Inositol-1,5-diphosphate (sodium salt) - ≥98% 2007-06-13 1.145377532228 d-myo-inositol-1-5-diphosphate-sodium-salt 1,5-IP2 (sodium salt); Ins(1,5)-P2 (sodium salt) inositol phosphates IP3 signaling transduction signalling cells InsP phosphitidylinositols phospholipases cPLC 1.145377532228
10007777 D-myo-Inositol-1-phosphate (sodium salt) - ≥98% 2006-01-13 8.432564185895 d-myo-inositol-1-phosphate-sodium-salt Ins(1)P1 (sodium salt); 1-IP1 (sodium salt) phosphates IP1 signals transductions InsP phosphatidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels meso compounds Xenopus oocytes 8.432564185895
10008456 D-myo-Inositol-2,3,4,5-tetraphosphate (ammonium salt) - ≥98% 2007-06-25 8.227034990791 d-myo-inositol-2-3-4-5-tetraphosphate-ammonium-salt 2,3,4,5-IP4 (ammonium salt); Ins(2,3,45)-P4 (ammonium salt) inositol phosphates IP3 signals transduction InsP phosphitidylinositols phospholipases cPLC signaling signalling 8.227034990791
10008423 D-myo-Inositol-2,3,5-triphosphate (ammonium salt) - ≥98% 2008-09-30 3.758051974626 d-myo-inositol-2-3-5-triphosphate-ammonium-salt 2,3,5-IP3 (ammonium salt); Ins(2,3,5)P3 (ammonium salt) phosphates IP3 signal transduction InsP phosphitidylinositols phospholipase C PLC cell signaling calcium channels 3.758051974626
10007779 D-myo-Inositol-2,4,5-triphosphate (sodium salt) - ≥98% 2006-01-13 4.871147943523 d-myo-inositol-2-4-5-triphosphate-sodium-salt 2,4,5-IP3 (sodium salt); Ins(2,4,5)P3 (sodium salt) phosphates IP3 signals transductions InsP phosphitidylinositols Ins(1,4,5)P3 phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels analogs agonists rat hepatic receptors 4.871147943523
10008419 D-myo-Inositol-2,4-diphosphate (sodium salt) - ≥98% 2009-08-04 19.335009208102 d-myo-inositol-2-4-diphosphate-sodium-salt Ins(2,4)-P2 (sodium salt); 2,4-IP2 (sodium salt) phosphates IP2 signals transduction cells cycling apoptosis differentiation motility InsP phosphatidyl inositols IP3 second messengers biphosphates bisphosphates PtsIns phosphatidylinositol 106358-02-5 19.335009208102
10008424 D-myo-Inositol-2,5,6-triphosphate (sodium salt) - ≥98% 2008-10-10 3.758051974626 d-myo-inositol-2-5-6-triphosphate-sodium-salt 2,5,6-IP3 (sodium salt); Ins(2,5,6)P3 (sodium salt) phosphates IP3 signal transduction InsP phosphitidylinositols phospholipase C PLC cell signaling calcium channels L-myo-Inositol-2,4,5-triphosphate (sodium salt) 3.758051974626
10007782 D-myo-Inositol-3,4,5,6-tetraphosphate (sodium salt) - ≥98% 2006-01-13 11.561175288799 d-myo-inositol-3-4-5-6-tetraphosphate-sodium-salt 3,4,5,6-IP4 (sodium salt); Ins(3,4,5,6) - P4 (sodium salt) oligophosphates isomers kinases IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels Xenopus oocytes 11.561175288799
10008425 D-myo-Inositol-3,4,5-triphosphate (sodium salt) - ≥98% 2007-06-05 1.764137507673 d-myo-inositol-3-4-5-triphosphate-sodium-salt 3,4,5-IP4 (sodium salt); Ins(3,4,5)-P3 (sodium salt) inositols phosphate IP3 signal transduction InsP phosphitidylinositol phospholipase C PLC 1.764137507673
10007778 D-myo-Inositol-3-phosphate (sodium salt) - ≥98% 2006-01-13 9.889567760805 d-myo-inositol-3-phosphate-sodium-salt Ins(3)P1 (sodium salt); 3-IP1 (sodium salt) phosphates IP3 signals transductions InsP phosphitidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels dephosphorylation 9.889567760805
10008418 D-myo-Inositol-4,5-diphosphate (sodium salt) - ≥98% 2007-01-04 5.157686057848 d-myo-inositol-4-5-diphosphate-sodium-salt Ins(4,5)-P2 (sodium salt); 4,5-IP2 (sodium salt) IP3 myo-inositols Ins(1,4,5)P3 Ins(4,5)P2 cells signaling transduction diphosphates salts InsPs phosphorylation receptors messengers inositol-4,5-biphosphate hydrolysis intracellular calcium PLC phospholipases signalling 5.157686057848
10008437 D-myo-Inositol-4-phosphate (ammonium salt) 142760-33-6 ≥98% 2006-10-18 6.609854972376 d-myo-inositol-4-phosphate-ammonium-salt 4-IP1 (ammonium salt); Ins(4)P1 (ammonium salt) phosphates IP4 signals transductions InsP phosphatidylinositols phospholipases C PLC messengers cellular cells hydrolysis ER endoplasmic reticulum calcium Ca2+ Ca++ channels dephosphorylation polyphosphates monophosphatase PtdIns 6.609854972376
9000639 Docosahexaenoyl Serotonin Exclusive 283601-58-1 ≥98% ✓ 2010-05-18 5.499368587214 docosahexaenoyl-serotonin N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA L-alpha-Glycerylphosphorylcholine L alpha Glycerylphosphorylcholine Glycerophospholipids Choline Choline Glycerophospholipids Phosphoglycerides Choline 3-Phosphocholine Glycerol Glycerylphosphorylcholine Glycerophosphate Choline Glycerol 3-Phosphocholine Glycerol 3 Phosphocholine Choline Phosphoglycerides Glycerophosphorylcholine Choline Glycerophosphate Alphoscerate Choline Phosphatidylcholines Choline Alphoscerate Alfoscerate Choline Phosphatidylcholine Choline Alfoscerate 5.499368587214
10460 Doramapimod 285983-48-4 ≥98% 2011-06-02 17.570828729282 doramapimod BIRB-796 p38 MAPKs inflammation TNFα TNF-α TNF α TNFalpha TNF-alpha TNF alpha JNKs inhibitors proteins kinases tumors necrosis factors LPS THP.1 cells THP1 BIRB796 BIRB 796 mitogen activated mitogen-activated proinflammatory cytokins interleukin-1 IL IL-1 interleukin 1 17.570828729282
13352 EHNA (hydrochloride) New - ≥98% 2011-10-07 653.841694290976 ehna-hydrochloride 51350-19-7 79763-32-9 59262-86-1 ADA reversible adenosine deaminase inhibitors inhibits inhibition cGMP PDE2 potent PDE1 PDE3 PDE4 phosphodiesterase ardioprotective ischemia stem cells 653.841694290976
10964 Eicosapentaenoyl Ethanolamide 109001-03-8 ≥98% 2011-06-22 40.016432517759 eicosapentaenoyl-ethanolamide EPEA cannabinoids CBSs endocannabinoids forensic sciences signals signaling N-acylethanolamide N-acylethanolamine NAE dietary restrictions lifespans TOR nematodes eicosapentaenoic acids inflammation anti-inflammatory 40.016432517759
9000640 Eicosapentaenoyl Serotonin Exclusive 199875-71-3 ≥98% ✓ 2010-09-10 1.115548539858 eicosapentaenoyl-serotonin N-arachidonoyl serotonins AA-5-HT AA5HT AA 5 HT AA-5HT AA5HT antagonists fatty acids Amide hydrolase FAAH transient receptors potential vanilloid type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA Triacylglycerols Triacylglycerol Triglycerides 1.115548539858
10010238 Erbstatin Analog 63177-57-1 ≥98% 2008-06-06 0.934806629835 erbstatin-analog Methyl 2,5-dihydoxycinnamate analogs EGF EGFR inhibitors inhibits inhibition tyrosine kinase DNA synthesis cell cycle proliferation cancers 0.934806629835
10483 Erlotinib 183321-74-6 ≥98% 2010-08-11 36.857933420298 erlotinib Tarceva™; CP 358,774; NSC 718781 tyrosine kinase inhibitor inhibits inhibiting epidermal growth factor receptors EGFR cancers tumor cyclin-dependent cyclin dependent kinase 2 CDK-2 CDK 2 CDK2 JAK-2 JAK2 JAK JAK2V617F CP-358,774 CP-358774 CP 358774 CP358774 CP358,774 NSC-718781 NSC718781 OSI-744 OSI744 R-1415 R1415 R 1415 OSI 744 Quinazolines 36.857933420298
10010501 Farnesyl Thiosalicylic Acid 162520-00-5 ≥96% 2008-06-02 22.247108655617 farnesyl-thiosalicylic-acid Salirasib; FTS ras inhibitors inhibition inhibits cancer anti-cancer anticancer prenylation farnesylation signal transduction oncogene atherosclerosis farnesylthiosalicylic acid 22.247108655617
13175 Farnesyl Thiosalicylic Acid Amide Exclusive 1092521-74-8 ≥96% ✓ 2009-02-26 8.649392265193 farnesyl-thiosalicylic-acid-amide Salirasib Amide; FTS Amide Ras degradation cells signaling signalling tumors glioblastoma cancers inhibitors inhibits inhibition 8.649392265193
13179 FKGK 11 1071000-98-0 ≥98% 2009-06-30 12.667116022099 fkgk-11 Phospholipases A2 iPLA2 inhibitors signal transduction inhibition PLAs 12.667116022099
11018 Forskolin New 66575-29-9 ≥98% 2012-01-03 375.454346992020 forskolin NSC 357088; HL 362; L 75-1362B; NSC 375489; Coleonol colforsin forslean HL 362 HL362 HL-362 L 75-1362B L75-1362B L-75-1362B NSC 357088 NSC357088 NSC-357088 NSC 375489 NSC375489 NSC-375489 cAMP signaling adenylyl cyclase diterpene Indian Coleus plants cyclic AMP cells tissues ATP transporters ions channels expressions regulations G proteins G-proteins 64657-11-0 375.454346992020
13166 Gefitinib 184475-35-2 ≥98% 2010-02-11 29.666398864333 gefitinib Iressa™; ZD1839 EGFR-TK EGFRs TKs epidermal growth factors inhibitors cancers signal transduction tyrosine kinases inhibits inhibited NSCLC Quinazolinones 29.666398864333
13355 Geldanamycin 30562-34-6 ≥98% 2010-07-29 28.221732797588 geldanamycin NSC 122750 NSC 212518 antibiotics heat shock proteins 90 Hsp90 GRP94 gp96 genes expression cells proliferation apoptosis angiogenesis c-jun adenocarcinoma cancers AP-1 steroids receptors 2,5-Cyclohexadiene-1,4-Diones 1,4-Benzoquinones 1,2-Benzoquinones p-Benzoquinones-o-Benzoquinones Benzoquinones Benzodiones Quinones 28.221732797588
13127 GW 4869 6823-69-4 ≥90% 2009-06-10 50.452836095763 gw-4869 inhibitors sphingomyelin sphingomyelinase neutral acidic TNF-α ceramides cells death GW4869 gw-4869 50.452836095763
13345 GYY 4137 Exclusive 106740-09-4 ≥95% ✓ 2009-07-31 114.901140270104 gyy-4137 hydrogen sulfides H2S gaseous mediators nitric oxides NOs donors vasodilator antihypertensive anti-hypertensive rats spontaneously hypertensive hypertension models endotoxic shock TNF-α TNFα TNF α TNF-a TNFa IL-1b IL1b IL-1β IL1β IL-6 IL6 NFkB NF-kB NF-κB NFκB iNOS COX-2 COX2 PGE2 110-91-8 106740-08-3 114.901140270104
10010556 H-89 127243-85-0 ≥98% 2008-07-08 23.596298342542 h-89 5-Isoquinolinesulfonamide; Protein Kinase Inhibitor H-89 inhibitors inhibits inhibition PKA cAMP cell signaling protein kinase S6K1 MSK1 ROCK-II ROCKII PKB.alpha. PKBalpha PKBa MAPKAP-K1b MAPKAPK1b H89 H 89 23.596298342542
10010249 H-8 (hydrochloride) 113276-94-1 ≥98% 2008-07-17 12.611243093923 h-8-hydrochloride Protein Kinase Inhibitor H-8 PKA PKG PKC MLCK cyclin C CDK8 cyclin H CDK7 p36 signal transduction inhibitor inhibits inhibition transcription 84478-11-5 12.611243093923
13312 H-9 (hydrochloride) - ≥98% 2009-07-14 12.197817679558 h-9-hydrochloride Protein Kinase Inhibitor H-9 proteins kinases inhibitors inhibits inhibitions PKCs PKAs PKGs cGMPs cAMPs signal transductions competitive potent PKA-mediated mediated phosphorylation 84468-17-7 12.197817679558
13205 Halopemide Exclusive 59831-65-1 ≥98% ✓ 2009-04-21 14.567127071823 halopemide R34301; NSC 354856 inhibitors phospholipases D PLD PLD1 PLD2 dopamine receptors inhibits inhibition potent cells DP nueraleptic 14.567127071823
13347 IBMX 28822-58-4 ≥98% 2009-10-27 444.424014732964 ibmx NSC 165960; 1-Methyl-3-Isobutylxanthine; Isobutylmethylxanthine inhibitor cAMP cGMP phophodiesterases PDE1 PDE2 PDE3 PDE4 PDE5 PDE7 PDE11 PDE8A PDE8B PDE9 cyclic-nucleotides methylxanthines caffeine theophylline adenosine receptors antagonist SC 2964 SC-2964 SC2964 IMX NSC165960 NSC-165960 xanthine 444.424014732964
13624 Icariin 489-32-7 ≥97% 2010-02-11 1.971491712706 icariin PDE5 inhibitors flavonoids differentiation cancers proliferation flavonols E brevicornum horny goat weed BMP2 ED erectile dysfunction 2-Phenyl-Benzopyrans 2 Phenyl Benzopyrans 2-Phenyl-Chromenes 2 Phenyl Chromenes Bioflavonoids Flavonoids 1.971491712706
13314 Indirubin-3'-monoxime 160807-49-8 ≥98% 2009-07-15 13.505690607734 indirubin-3-monoxime glycogen synthase kinase-3β GSK-3β tau proteins Alzheimer's diseases cyclin-dependent kinases CDK CDK1 cyclin A B E D1 CDK4 CDK2 CDK5 p35 growth proliferation synchronization cells arrest G2/M phases phosphorylation inhibits inhibition inhibitors 13.505690607734
10004974 Ionomycin New 56092-81-0 ≥98% 2011-09-30 18.516693051647 ionomycin ionophores calcium transport streptomyces conglobatus intracellular cytokines membranes stores biological SQ23377 SQ-23377 SQ 23377 18.516693051647
13843 IRAK-1 Polyclonal Antibody - 2010-11-11 0E-12 irak-1-polyclonal-antibody Interleukin-1 Receptor-Associated Kinase 1 NF-kB NF-κB NFkB NFκB NF kB NFκB NF-kappaB kappaB NFkappaB NF.kappa.B NF-.kappa.B .kappa.B nuclear factor κB serine threonine serine/threonine IL-1 IL1 IL 1 receptors signaling cascase activation members novel cytokines IL-18 IL18 18 IGIF antibodies western blots blotting immunoblotting WB IP immunoprecipatation IRAK-1 0E-12
13288 Itraconazole 84625-61-6 ≥95% 2011-02-22 83.955082872927 itraconazole hedgehogs signaling cancer antifungal inverse agonist patched smoothened Canditral Cladosal 100 Itralek Itrizole Oriconazole Orungal R 51211 Sempera Spherazole CR IR Sporal Sporamelt Sporanox Sporonox Traconal Triasporin Janssen-Cilag Brand of Itraconazole Janssen Cilag Brand of Itraconazole Janssen Brand of Itraconazole Itraconazole Janssen Brand Itraconazole Sporanox R-51211 R 51211 Orungal R51211 83.955082872927
13659 IWR-1-endo 1127442-82-3 ≥98% 2010-03-23 12.242836095764 iwr-1-endo Wnt cancers embryonic developments tissues homeostasis embryogenesis tumorigenesis stem cells β-catenin genes expression transcription inhibitors inhibits inhibition proteasomes Apc Axin2 Ck1 Gsk3β IWR-1-exoendo-1,3(4)-beta-D-glucanase Endo-1,3(4)-beta-Glucanase Endo-1,3(4)-B-Glucanase beta-(1-3,1-4)glucanase 12.242836095764
13598 IWR-1-exo 1127442-87-8 ≥98% 2010-03-23 9.775248618785 iwr-1-exo Wnt cancers embryonic developments tissues homeostasis embryogenesis tumorigenesis stem cells β-catenin genes expressio Cellobiohydrolase, 1,4-beta-D-Glucan 1,4-beta-D-Glucan Cellobiohydrolase 1,4 beta D Glucan Cellobiohydrolase 1,4-beta-Cellobiosidase, Cellulose Cellulose 1,4-beta-Cellobiosidase Cellulose 1,4 beta Cellobiosidase Beta-Glucancellobiohydrolase Beta Glucancellobiohydrolase Exo-Cellobiohydrolase Exo Cellobiohydrolase Cellobiohydrolase II Cellobiohydrolase I Cellobiohydrolase A Cellobiohydrolase Exoglucanase II CEL1 Protein CbhI Proteinn transcription inhibitors inhibits inhibition controls 9.775248618785
13924 IκBα (Phospho-Ser32/36) Monoclonal Antibody - biotin (Clone 39A1413) - 2010-09-29 0.140883977900 i-b-phospho-ser32-36-monoclonal-antibody-biotin-clone-39a1413 antibodies IκBα IkBa IκBa IkBα IκB-α IκB α intracellular NF-κB NFκB NF κB slienced slience inhibitory inhibits inhibition inhibitor proteins asutoregulated auto-regulated auto regulated regulates phosphorylated kinase complex IKK IKK1 IKK2 IKK3 IKK-1 IKK-2 IKK-3 1 2 3 IKK1/a IKK1-a IKK1a IKK2/b IKK2-b IKK2b IKK3/g IKK3-g IKK3g degradation phosphorylation dimers translocates nucleus genes target serines serine32 serine36 serine-32 serine-36 32 36 ser32 ser36 ser-32 ser-36 ser EIA ELISA biotins biotinylated inflammation genes regulation signal transduction 0.140883977900
13923 IκBα (Phospho-Ser32/36) Monoclonal Antibody (Clone 39A1413) - 2010-09-29 14.705022601707 i-b-phospho-ser32-36-monoclonal-antibody-clone-39a1413 antibodies IκBα IkBa IκBa IkBα IκB-α IκB α intracellular western blots blotting immunoblotting WB NF-κB NFκB NF κB slienced slience inhibitory inhibits inhibition inhibitor proteins asutoregulated auto-regulated auto regulated regulates phosphorylated kinase complex IKK IKK1 IKK2 IKK3 IKK-1 IKK-2 IKK-3 1 2 3 IKK1/a IKK1-a IKK1a IKK2/b IKK2-b IKK2b IKK3/g IKK3-g IKK3g degradation phosphorylation dimers translocates nucleus genes target immunoprecipitation IP serines serine32 serine36 serine-32 serine-36 32 36 ser32 ser36 ser-32 ser-36 ser genes regulation inflammation signal transduction 14.705022601707
13921 IκBα Polyclonal Antibody - 2010-09-23 0.140883977900 i-b-polyclonal-antibody antibodies IκBα IkBa IκBa IkBα IκB-α IκB α intracellular western blots blotting immunoblotting WB NF-κB NFκB NF κB slienced slience inhibitory inhibits inhibition inhibitor proteins asutoregulated auto-regulated auto regulated regulates phosphorylated kinase complex IKK IKK1 IKK2 IKK3 IKK-1 IKK-2 IKK-3 1 2 3 IKK1/a IKK1-a IKK1a IKK2/b IKK2-b IKK2b IKK3/g IKK3-g IKK3g degradation phosphorylation dimers translocates nucleus genes target 0.140883977900
10011246 Janex 1 202475-60-3 ≥98% 2008-12-17 2.433149171271 janex-1 WHI-P131 inhibitors inhibits inhibition JAK3 apoptosis leukemias anti-inflammatory antiinflammatory lymphocytes WHIP131 Janex 1 2.433149171271
10008131 JNJ-10198409 627512-69-0 ≥98% 2006-10-18 13.369116022100 jnj-10198409 PDGF-BB tyrosine kinases inhibits inhibition inhibitors growth factors receptors platelet-derived antiangiogenic antiproliferative coronary artery smooth muscle cells antagonists ATP binding hydrolysis tumors angiogenesis 13.369116022100
11511 JNK2 Polyclonal Antibody New - 2011-11-18 14.444444444444 jnk2-polyclonal-antibody SAPK1a; p54a; MAPK9 antibody; c-Jun Amino Terminal Kinase 2 c-Jun kinases JNKs MAP phosphorylation JNK1 JNK3 nuclear signals transduction proteins transcription factors p53 Western blots WB blotting JNKs JNK-1 JNK-2 JNK-3 14.444444444444
10009458 JTE-013 383150-41-2 ≥98% 2007-01-18 98.777587476979 jte-013 reverses inhibition inhibits coronary artery smooth muscles lipids cells proliferation cytoskeletal morphogenesis GPCRs protein-coupled receptors antagonists S1P2 humans rats EDG5 sphingosines sphingosine-1-phosphates sphingosine1 inhibitors JTE013 FDG-5 cancers 98.777587476979
10010239 Kenpaullone 142273-20-9 >98% 2007-09-04 11.609281767956 kenpaullone NSC 664704; 9-Bromopaullone GSK-3.beta. cyclin-dependent kinase cyclin CDK inhibitors inhibits inhibition proliferations cell cycle cancers 11.609281767956
13243 KH7 330676-02-3 ≥98% 2009-09-18 118.266629834254 kh7 sAC soluble adenylyl cyclase cAMP inhibitors inhibits inhibition cells signaling signal transduction second messenger KH 7 KH-7 signalling cyclic AMP 118.266629834254
13318 KN-62 127191-97-3 ≥98% 2009-07-16 23.531558011049 kn-62 inhibitors calcium calmodulin-dependent kinase II CaM kinase II purinergic receptors P2RX7 P2X7 inhibition inhibited selective permeableCaMKII calcium ca modulation CaMK11CaMK2 23.531558011049
9000890 KN-92 (hydrochloride) - ≥98% 2011-05-25 26.754364640883 kn-92-hydrochloride Ca2+/calmodulin-dependents kinases II CaMKII KN-93 controls cells cycles inhibitors inhibited inhibition NIH 3T3 13319 inhibits KN92 KN 92 KN93 KN 93 26.754364640883
13319 KN-93 139298-40-1 ≥98% 2009-08-05 36.029337016574 kn-93 inhibitors inhibits inhibition Ca2+ calmodulin dependent Ca2+/calmodulin-dependent kinase II CaMKII histamine parietal cells cardiac myocytes 5-LO 5-lipoxygenase HIF-1a HIF-1α HIF1α colon cancers phosphorylation CAM 36.029337016574
10011011 KT 5720 108068-98-0 ≥98% 2009-01-20 120.979786898185 kt-5720 PKAs cAMPs signaling proteins kinase inhibitors inhibits inhibition phosphorylase kinase PDK1 MEK MSK1 PKα GSK3β KT5720 KT-5720 120.979786898185
10010965 KT 5823 126643-37-6 ≥95% 2009-01-15 134.916215469613 kt-5823 cGMP PKGs proteins kinases G inhibitors inhibits inhibition nitric oxides NO antibiotic KT5823 KT-5823 134.916215469613
10011565 L-161,982 147776-06-5 ≥98% 2009-02-26 57.124640883978 l-161-982 PGEs PGE2 EPs EP4 receptors antagonist bone formation inflammation cells proliferation colon cancers L161982 L-161982 57.124640883978
10010631 Latrunculin B 76343-94-7 ≥97% 2009-02-20 66.662928176795 latrunculin-b monomeric actins G-actin G actins F-actin F inhibitors inhibits inhibition cytoskeleton 66.662928176795
10010329 Lavendustin C 125697-93-0 ≥98% 2008-07-08 13.433480662983 lavendustin-c HDBA; NSC 666251 EGFR kinases tyrosine pp60c-src pp60csrc CamKII SOD neutrophil activation erbstatin inhibitor inhibits inhibition Lavendustin-C 13.433480662983
10008426 L-myo-Inositol-1,4,5-triphosphate (sodium salt) 2068-89-5 ≥98% 2009-09-14 3.623835832675 l-myo-inositol-1-4-5-triphosphate-sodium-salt 1,4,5-IP3 (sodium salt); Ins(1,4,5)P3 (sodium salt); D-myo-Inositol-3,5,6-triphosphate (sodium salt) inositols phosphates calcium cells signaling isomers D-myo-inositol-1,4,5-triphosphate 2068-89-5 3.623835832675
10010497 Manumycin A 52665-74-4 ≥98% 2008-06-25 20.587458563536 manumycin-a UCF 1C; NSC 622141 farnesyltransferase inhibitors inhibits inhibition cancer antitumor anti-tumor signal transduction Ras farnesylation NF-.kappa.B NF-kB NF-kappaB 20.587458563536
13846 MEK1/2 Polyclonal Antibody - 2010-11-17 0E-12 mek1-2-polyclonal-antibody MAP Kinase Kinase 1/2 MEK-1/2 MEK1/2 MEK1 MEK2 MEK-1 MEK-2 MEK 1 2 kinases MAP MAPK cascade cells growth differentiation synaptic plastic plasticity brain phosphorylation serines Ser218 Ser222 Ser-218 Ser-222 Sers 218 222 theronine tyrosine ERK western blotting blots immunoblotting WB antibodies affinity pruified 0E-12
10009518 MEK1 (Phospho-Thr292) Polyclonal Antibody - 2007-01-12 0E-12 mek1-phospho-thr292-polyclonal-antibody MAP Kinase Kinase 1; MAPKK1 antibodies WB western blot MEK 1 phosphorylation MAP kinase cell growth differentiation threonine tyrosine phospho-specific blotting immunoblotting 0E-12
10009517 MEK1 (Phospho-Thr386) Polyclonal Antibody - 2007-01-11 0E-12 mek1-phospho-thr386-polyclonal-antibody MAPK1; MAP Kinase Kinase 1 antibodies WB western blot MEK 1 phosphorylation MAP kinase cell growth differentiation threonine tyrosine phospho-specific blotting immunoblotting 0E-12
13848 MEKK2 Polyclonal Antibody - 2010-12-21 0E-12 mekk2-polyclonal-antibody MAP Kinase/ERK Kinase Kinase 2; Dual Specificity MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinase 2; MAP3K2; MAPKKK2 MEKs MEK-2 MEK 2 MAPKs kinases MAPs mitogen-activated mitogen activated proteins signaling pathway phosphorylate IkB I.kappa.B IkappaB IκB NF-κB NF-kappaB NF-.kappa.B NFκB NF.kappa.B NFkB T-cells T cells cytokine genes expressions mast cells epidermal growth factor EGRs fibroblast growth factor-2 factor 2 FGF-2 FGF2 FGFs 2 signals rheumatoid arthritis LPS-TLR4 LPS TLR4 TLR-4 TLR 4 ligands phosphorylation western blots blotting immunoblotting WB immunohistochemistry IHC MAP kinase kinase kinase 0E-12
10010236 ML-9 105637-50-1 ≥98% 2008-01-21 16.362486187845 ml-9 PKB Akt inhibitors inhibits inhibition serine/threonine kinase PKA P90S6 MAP kinases cancers anti-cancers insulin glucose transports calcium channels calmodulin intracellular smooth muscles asthma 16.362486187845
10230 (+)-Muscarine (iodide salt) 24570-49-8 ≥95% 2010-05-06 0.837392265193 -muscarine-iodide-salt neurochemistry 300-54-9 2438-77-9 poisonous mushroom acetylcholine G proteins Alzheimer's disease signal transduction L-muscarine Amanita muscaria 0.837392265193
13746 MyD88 Polyclonal Antibody - 2010-02-05 29.770497237569 myd88-polyclonal-antibody proteins antibodies western blots blotting immunoblotting WB interleukin-1 interleukins 1 IL-1 ILs signaling N-terminal NF-κB NFκB NF κB death domain signalling 29.770497237569
13063 N-3-oxo-tetradecanoyl-L-Homoserine lactone Exclusive 177158-19-9 ≥98% ✓ 2009-01-29 10.987544505831 n-3-oxo-tetradecanoyl-l-homoserine-lactone N-3-oxo-myristoyl-L-Homoserine lactone; 3-oxo-C14-HSL quorum sensing bacteria biofilm gene expressions growth putisolvin lactones HSLs 10.987544505831
13136 N-acetyl-D-Glucosamine 7512-17-6 ≥98% 2009-03-13 59.476813996317 n-acetyl-d-glucosamine Marine Sweet; GlcNAc; NSC 524344; NAG monosaccharide glucose O-GlcNAc alzheimer's disease genes expressions chitin cells signalling signaling post-translational modification signal transduction 59.476813996317
10011060 N-acetyl-D-Mannosamine 7772-94-3 ≥95% 2008-11-11 0.232044198895 n-acetyl-d-mannosamine ManNAc acids sialylation proteinuria glomerular diseases neuromuscular disorders HIBM sialic 0.232044198895
10011203 N-dodecanoyl-L-Homoserine lactone Exclusive 137173-46-7 ≥98% ✓ 2009-01-06 17.923863720073 n-dodecanoyl-l-homoserine-lactone C12-HSL; dDHL quorum sensing bacteria biofilm gene expressions NF-kb NFkb macrophage keratinocyte C12-Homoserine Lactone 17.923863720073
9000710 N-dodecanoyl-L-Homoserine lactone-3-hydrazone-biotin Exclusive - ≥95% ✓ 2011-01-17 12.142412523020 n-dodecanoyl-l-homoserine-lactone-3-hydrazone-biotin N-dodecanoyl-L-HSL-3-hydrazone-biotin quorum sensing proteolysis affinity probes avidin lactones HSLS biotinamide biotinimide biotins 12.142412523020
13755 NF-κB (p50) Monoclonal Antibody (Clone 2J10D7) - 2010-02-05 11.177348066298 nf-b-p50-monoclonal-antibody-clone-2j10d7 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB nuclear transcription factors cytokines UV radiations stress injury bacterial viral cells growth differentiation proliferation apoptosis inflammation DNA AIDS cancers arthritis western blots blotting immunoblotting IHC WB immunohistochemistry 11.177348066298
13754 NF-κB (p50) Polyclonal Antibody - 2010-04-27 11.177348066298 nf-b-p50-polyclonal-antibody NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB nuclear transcription factors DNA p65 N-terminal binding western blots blotting immunoblotting WB antibodies 11.177348066298
13756 NF-κB (p65) Monoclonal Antibody-biotin (Clone 112A1021) - 2010-02-11 20.718358326756 nf-b-p65-monoclonal-antibody-biotin-clone-112a1021 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting WB biotins biotinylated biontinylation 112A1021 clones 20.718358326756
13752 NF-κB (p65) Monoclonal Antibody (Clone 112A1021) - 2010-02-11 23.701783741120 nf-b-p65-monoclonal-antibody-clone-112a1021 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting flow cytometry FC WB immunohistochemistry IHC 23.701783741120
13751 NF-κB (p65) NLS Polyclonal Antibody - 2010-02-11 21.821562746645 nf-b-p65-nls-polyclonal-antibody Nuclear Factor-κB (p65) Nuclear Localization Signal NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB transcription factors N-terminal C-terminal terminals terminus signals tissues nuclear receptors western blots blotting immunoblotting WB immunocytochemistry ICC antibodies 21.821562746645
13757 NF-κB (p65) Polyclonal Antibody (aa 2-17) - 2010-02-11 16.365951065509 nf-b-p65-polyclonal-antibody-aa-2-17 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting WB amino acids 2 7 16.365951065509
13753 NF-κB (p65) Polyclonal Antibody (aa 538-546) - 2010-02-11 20.718358326756 nf-b-p65-polyclonal-antibody-aa-538-546 NFκB NF κB NF-.kappa.B NF.kappa.B NFkB NF-kB genes apoptosis viral replications tumorigenesis diseases inflammations N-terminal DNA DNA-binding binding western blots blotting WB amino acids 538 546 20.718358326756
10649 Niclosamide 50-65-7 ≥95% 2011-01-12 1.259751381215 niclosamide antihelminthic helminth tapeworms inhibitors STAT3 cancers proliferation anti-helminthic salicylanilide Du 145 DU145 DU-145 Niclosamide, 2-Aminoethanol (1:1) Aventis Brand of Niclosamide Bayer Brand of Niclosamide Clonitralide Niclosamide Bayluscide Bayer 2353 Trédémine Niclocide Radewerm Phenasal Bayer 73 Yomesan Fenasal 1.259751381215
10010422 Nilotinib 641571-10-0 ≥98% 2009-10-23 32.281740331491 nilotinib AMN107 tyrosine kinases inhibitors therapy cancer Bcr/Abl chronic myeloid leukemia MLL philadelphia chromosomes acute lymphoblastic ALL imatinib gleevec genes expression DNA helicase complex cyclins cyclin-dependent cells proliferation 32.281740331491
11040 Nodinitib-1 New 799264-47-4 ≥95% 2012-01-20 88.584858809084 nodinitib-1 ML130; CID-1088438 NOD1 NLR innate immunity NF-κB signaling inflammation MAPK inflammatory diseases inhibitors inhibition inhibits NACHT leucine proteins bacterial bacteria ligands stress kinases interferons polymorphisms genes asthma bowel multiple sclerosis MS cells CD83 CD86 HLA-DR IL-1β IL-6 TNFα 88.584858809084
13094 N-pentadecanoyl-L-Homoserine lactone Exclusive 182359-66-6 ≥98% ✓ 2009-03-02 13.809818468823 n-pentadecanoyl-l-homoserine-lactone C15-HSL C15HSL C15-HSL AHL quorum sensing signaling signalling autoinducers bacterias 13.809818468823
10011255 NSC 210902 51726-83-1 ≥95% 2008-09-15 4.363314917128 nsc-210902 Inhibitor inhibits inhibition CK2 kinase cell signaling apoptosis cancers NSC210902 4.363314917128
13196 NSC 23766 (hydrochloride) 1177865-17-6 ≥98% 2010-07-20 20.106572539390 nsc-23766-hydrochloride 733767-34-5 GTPases cells cycles growth proliferations cell-cell adhesions motility differentiation guanine nucleotides exchange factors GEFs inhibitors inhibits inhibition cell migration Aminoquinolines angiogenesis leukemia cancers gene expression Rac1 Inhibitor 20.106572539390
10011200 N-tetradecanoyl-L-Homoserine lactone Exclusive 202284-87-5 ≥98% ✓ 2009-01-06 14.010161141804 n-tetradecanoyl-l-homoserine-lactone tDHL; C14-HSL quorum sensing bacterias biofilm gene expressions growth proteolytic acitivity activities migration 14.010161141804
10009277 Nuclear Extraction Kit - 2007-05-11 87.070767341927 nuclear-extraction-kit assays kits proteins transcription factors cytoplasmic fractions cells tissue homogenates EMSA extracts electrophoretic mobility shift western blotting blots 87.070767341927
13641 NVP-AEW541 (hydrochloride) - 98% 2010-07-28 42.472298342541 nvp-aew541-hydrochloride 475488-34-7 IGF-1R Insulin-like growth factor I receptors tyrosine kinases angiogenesis cells proliferation cancers inhibitors inhibition inhibits 701294-63-5 Ins-R NWT-21 Pyrroles 42.472298342541
10006803 O-1602 317321-41-8 >98% 2005-09-12 10.815055248618 o-1602 abnormal cannabidiols CB1 CB2 receptors vasorelaxation neurochemistry neuroscience central cannabinoids peripheral selective antagonists nonendothelium-dependant vasodilation nitric oxides NOs inhibits inhibitors inhibition vasorelaxant cannabinoids cbs synthetic 10.815055248618
10006804 O-1821 35482-50-9 >97% 2005-09-12 18.876795580110 o-1821 abnormal cannabidiol central cannabinoids peripheral CB1 CB2 receptors vasorelaxation neurochemistry neuroscience antagonists synthetic regioisomer endothelium dependent vasodilation cannabinoids cbs synthetic 18.876795580110
10004914 O-1918 536697-79-7 >98% 2005-09-09 9.860102604577 o-1918 antagonists abnormal cannabinoids cannabidiols cannabidiol-mediated synthetic regioisomers CB1 CB2 responsiveness psychotropics activity induces endothelium-dependent vasodilations NO-independent nitric oxides mechanisms analogs endothelial receptors inhibits inhibition inhibitors vasorelexants in vitro blocks induced activations PI3-kinases Akt pathway umbilical vein cells neuroscience neurochemistry O1918 0-1918 cannabinoids cbs synthetic 9.860102604577
10010299 Oleoyl 3-carbacyclic Phosphatidic Acid Exclusive - ≥95% ✓ 2009-10-14 14.531505524862 oleoyl-3-carbacyclic-phosphatidic-acid 3-ccPA 18:1 cyclic phosphatidic acids cPAs lysophosphatidic LPA ccPA 3ccPA oleate transcellular migration MM1 cells mesothelial autotoxin cancer survival growth migration invasion metastasis antagonist LPA1 LPA2 LPA3 476310-24-4 14.531505524862
9000629 Oleoyl Serotonin Exclusive 1002100-44-8 ≥98% ✓ 2010-05-18 5.718153117601 oleoyl-serotonin N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA Hydrolase Long-Chain Fatty-Acyl-CoA Fatty-Acyl-CoA Hydrolase Long-Chain Long-Chain Fatty-Acyl-CoA Hydrolase Long Chain Fatty Acyl CoA Hydrolase Palmitoyl Coenzyme A Hydrolase Acylhydrolase Oleoyl-CoA Thioesterase Fatty Acyl Oleoyl-CoA Acylhydrolase Oleoyl CoA Acylhydrolase Hydrolase Palmitoyl-CoA Deacylase, Palmitoyl CoA CoA Deacylase, Palmitoyl Thioesterase, Palmitoyl Palmitoyl-CoA Hydrolase Palmitoyl CoA Hydrolase Palmitoyl CoA Deacylase Hydrolase Stearoyl CoA Fatty Acyl Thioesterase CoA Hydrolase Stearoyl Stearoyl CoA Hydrolase Palmitoyl Thioesterase Hydrolase Acyl CoA CoA Hydrolase Acyl Acyl CoA Hydrolase Thioesterase I 5.718153117601
9000694 Oleoyl Serotonin-d17 Exclusive - ≥99% deuterated product ✓ 2010-09-27 5.499368587214 oleoyl-serotonin-d17 N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA deuterateds deuteriums MS mass spectrometry GC-MS LC-MS GC/MS LC/MS standards 5.499368587214
10011301 p38 MAPK Monoclonal Antibody (Clone 9F12) - 2008-05-22 2.238987108655 p38-mapk-monoclonal-antibody-clone-9f12 p38 Mitogen-activated Protein Kinase; p38 MAPKα serine threonine serine-threonine cell cycles development apotosis kinases stress signals cytokines gene expression western blots immunoblotting immunocytochemisty ICC WB flow cytometry signal transduction signalling signaling blotting FC 2.238987108655
600008 p53 Cell-Based Activation/Translocation Assay Kit - 2009-03-10 12.453461223654 p53-cell-based-activation-translocation-assay-kit p53 dsDNA double-stranded tumors suppressors proteins guardians of the genomes cells cellular responses genotoxic stresses activity cycles arrests apoptosis senescence humans cancers mutations inactivated binding ubiquitination acetylation phosphorylation sumoylation neddylation methylation glycosylation damages oncogenes ribosomal cell-matrix matrices adhesion hypoxia p21 WAF1 Cip1 MDM2 GADD45 Cyclin G Bax IGF-BP3 bcl-2 Bcl-XL cyclins B1 MAP4 survivin HPV16 PARP-1 WT1 E1b/E4 degradation nucleus cytoplasms proteasomes promoter carcinogenesis endogenous wild-type heterogenous autosomal dominant disorders Li Fraumeni Syndromes nuclear extracts assays cell-based assay cell based assay cba 12.453461223654
10007358 Palmitic Acid methyl ester 112-39-0 >99% 2006-02-17 10.043711702661 palmitic-acid-methyl-ester MP; Methyl Palmitate esters saturated fatty acids synthesized synthesis plants animals acetyl coenzymes CoA energy storage 16-carbon dietary fats plasma lipoproteins expression COX-2 cyclooxygenase-2 cyclooxygenases proteins acylation lipids anchoring signaling signalling molecules 10.043711702661
10010298 Palmitoleoyl 3-carbacyclic Phosphatidic Acid Exclusive 910228-13-6 ≥95% ✓ 2009-11-03 12.327271568210 palmitoleoyl-3-carbacyclic-phosphatidic-acid 3-carbacyclic PA; 3-ccPA 16:1 cyclic phosphatidic acids cPAs lysophosphatidic LPA ccPA 3ccPA palmitoleate transcellular migration MM1 cells mesothelial autotoxins cancer survival growth migration invasion metastasis NPP2 ENPP2 ectonucleotide pyro phosphatase/phosphodiesterase 2 12.327271568210
10965 Palmitoleoyl Ethanolamide 94421-67-7 ≥98% 2011-06-27 21.131123388582 palmitoleoyl-ethanolamide POEA cannabinoids endocannabinoids CBs N-acylethanolamines signalling N-acylethanolamides NAEs signaling receptors pain lipid-derived 21.131123388582
10010293 Palmitoyl 3-carbacyclic Phosphatidic Acid Exclusive 476310-22-2 ≥95% ✓ 2009-10-07 15.449558011049 palmitoyl-3-carbacyclic-phosphatidic-acid 3-ccPA 16:0; 3-carbacyclic PA cyclic acids cPAs lysophosphatidic LPA ccPA 3ccPA palmitate transcellular migration MM1 cells mesothelial autotoxins cancers survival growth migration invasion metastasis 15.449558011049
9000630 Palmitoyl Serotonin Exclusive 212707-51-2 ≥98% ✓ 2010-05-18 5.850749802683 palmitoyl-serotonin N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA Hydrolase Long-Chain Fatty-Acyl-CoA Fatty-Acyl-CoA Hydrolase Long-Chain Long-Chain Fatty-Acyl-CoA Hydrolase Long Chain Fatty Acyl CoA Hydrolase Palmitoyl Coenzyme A Hydrolase Acylhydrolase Oleoyl-CoA Thioesterase Fatty Acyl Oleoyl-CoA Acylhydrolase Oleoyl CoA Acylhydrolase Hydrolase Palmitoyl-CoA Deacylase Palmitoyl CoA CoA Deacylase Palmitoyl Thioesterase Palmitoyl Palmitoyl-CoA Hydrolase Palmitoyl CoA Hydrolase Palmitoyl CoA Deacylase Hydrolase Stearoyl CoA Fatty Acyl Thioesterase CoA Hydrolase Stearoyl Stearoyl CoA Hydrolase Palmitoyl Thioesterase Hydrolase Acyl CoA CoA Hydrolase Acyl Acyl CoA Hydrolase Thioesterase I 5.850749802683
10994 Paxillin (Phospho-Tyr118) Polyclonal Antibody New - 2012-01-13 76.666666666667 paxillin-phospho-tyr118-polyclonal-antibody proteins LIM domains ERK-regulated scaffolds vinculin-binding phosphorylation Western blots blotting WB ERKs binds binding vinculin JNK 76.666666666667
13034 PD 0325901 391210-10-9 ≥98% 2009-03-13 53.446003627434 pd-0325901 MEK ERK RAS RAF MAPK tumors stem cells cancers differentiation signaling GSK3 kinase inhibitors inhibits inhibition pd325901 pd 325901 PD0325901 53.446003627434
9000988 PD 166326 New 185039-91-2 ≥98% 2011-11-30 115.092973659244 pd-166326 inhibitors cancers c-abl c-src Bcl/Abl tyrosine receptors kinases cells signaling leukemia CML chronic myelogenous leukemia PD-166326 PD166326 pyridopyrimidine STI571 mesylate 115.092973659244
10006727 PD 169316 152121-53-4 >98% 2006-04-12 22.468640549138 pd-169316 p38 mitogen-activated proteins kinases MAPK enzymes signal transductions inhibitors inhibits A C.alpha. apoptosis neuronal cells trophic factors potassium nerves growth pd169316 pd-169316 22.468640549138
13032 PD 173074 219580-11-7 ≥98% 2009-07-29 50.730632252544 pd-173074 fibroblast growths factors receptors FGFRs FGFR1 tyrosine kinase activity activities activation signals propagation inhibitors inhibition inhibits autophosphorylation PDGFR c-Src cSrc c Src EGFR InsR MEK PKC FGFR2 FGFR3 FGFR4 FGFR5 angiogenesis cancers tumors self-renewal self renewal stems cells ERK1/2 ERK-1/2 ERK 1/2 50.730632252544
10012431 PD 184161 Exclusive 212631-67-9 ≥98% ✓ 2009-06-09 37.587090169652 pd-184161 MEK inhibitors MAP kinase ERK signaling cancer MEK 1/2 inhibition inhibited ERK 1/2 potent selective pd184161 37.587090169652
10006726 PD 98059 167869-21-8 >98% 2005-09-12 34.785742693975 pd-98059 potent selective MAPK mitogen-activated proteins kinases family serines threonines cellular PD-98059 programs cells proliferation differentiation movement death noncompetitive inhibits inhibitors inhibition pathways activation MAPKK1 Raf MEK MAPKK2 MAPKK-1 PD98059 MAPKK-2 ERK 34.785742693975
10007191 PH Domain Leucine-rich Repeat Protein Phosphatase 1 Polyclonal Antibody - 2006-01-04 3.980020718231 ph-domain-leucine-rich-repeat-protein-phosphatase-1-polyclonal-antibody KIAA0606 Protein; PHLPP1; PLEKHE1 Protein; SCOP; Suprachiasmatic Nucleus Circadian Oscillatory Protein proteins diseases antibodies antisera antiserum western blots blotting immunocytochemistry ICC immunohistochemistry IHC cancers WB immunoblotting PH Domain Leucine-rich Repeat Protein Phosphatase Polyclonal Antibody 3.980020718231
10007192 PH Domain Leucine-rich Repeat Protein Phosphatase Blocking Peptide - 2006-01-30 2.371381215469 ph-domain-leucine-rich-repeat-protein-phosphatase-blocking-peptide Suprachiasmatic Nucleus Circadian Oscillatory Protein; SCOP; PLEKHE1 Protein; PHLPP; KIAA0606 Protein western blotting blots signaling signalling WB IHC ICC immunohistochemistry formalin-fixed paraffin-embedded immunocytochemistry proteins kinases Akt cells growth death serine residues Ser473 C-terminal hydrophobic motifs human cancers dephosphorylates dephosphorylation reduces activity apoptosis apoptotic colon glioblastomas lines tumors brain 2.371381215469
13581 Phosphine-biotin - ≥95% 2009-12-03 15.547767955801 phosphine-biotin DAz-1 DAz1 DAz 1 DAz-2 DAz2 DAz 2 sulfenic acids click chemistry azido groups ROS oxidation cysteine posttranslational modifications staudinger ligation P-Biotin click-tag 15.547767955801
10009209 PI-103 371935-74-9 >98% 2007-01-19 38.161966200845 pi-103 phosphoinositides PI3-kinases Phosphatidylinositols cancers Glioma DNA-PK mTOR inhibitors inhibits inhibition anti-proliferatives proliferation PI103 38.161966200845
13326 Pifithrin-α 63208-82-2 ≥95% 2009-07-16 29.561926795580 pifithrin p53 apoptosis DNA damage cyclin D1 C8 cells HUVECs endothelial cells dependent independent inactivator 29.561926795580
10009210 PIK-75 372196-67-3 ≥98% 2010-03-10 21.638544796614 pik-75 p110α PI3K insulin signaling signals cancers inhibitors inhibits inhibition signalling p110a phosphatidylinositol 3-kinase phosphorylation Akt activation mTORC1 PIP2 PIP3 p110β p110α p110γ p110beta p110 alpha p110.beta. p110.alpha. p110gamma p110.gamma.p110g Mixtures, Sulfonamide Sulfonamide Mixtures Sulfonamides 21.638544796614
11006 Piperlongumine New 20069-09-4 ≥98% 2011-10-24 61.978915008314 piperlongumine Piplartine 2859-009- 11042-67-4 25343-05-9 Keap1 Nrf2 antioxidants ROS cancers redox platelet aggregation tumorigenesis 61.978915008314
10728 PIT-1 Exclusive 53501-41-0 ≥98% ✓ 2011-03-25 15.554530386740 pit-1 PIP3 PtdIns-(3,4,5)-P3 PH domains cancers inhibitors Akt PDK1 PTENs proteins binding pituitary-specific transcription factors pit-1 pituitary-specific pit 1 GHF-1 GHF 1 pit-oct-unc pit oct unc POU growth hormones 15.554530386740
10459 PKC 412 120685-11-2 ≥98% 2010-07-27 32.418947974217 pkc-412 CGP 41251; N-Benzoylstaurosporine; Midostaurin; CGP 41231 inhibitors inhibits inhibition PKC412 PKC-412 serine/threonine serine threonine tyrosines kinases PKCα PKCβ PKCγ PKC-α PKC-β PKC-γ Syk Flk-1 Flk1 Akt PKA c-Kit cKit C-Fgr cFgr FLT3 FLT-3 PDFRβ PDFR-β VEGFR1 VEGF2 nitric oxide synthase eNOS apoptosis cancers angiogenesis signal transduction Staurosporine 32.418947974217
10007839 PLC thio-PIP2 (sodium salt) - >98% 2006-01-18 10.839585635359 plc-thio-pip2-sodium-salt phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono 10.839585635359
13198 PP2 172889-27-9 ≥98% 2010-09-20 31.691723756906 pp2 AGL 1879 PTK inhibitors inhibits inhibition Src kinase T cells T-cells enzymes AG1879 AG 1879 PP-2 PP 2 signalling tyrosine kinases tyrosine focal Tyr 577 adhesion kinases AG-1879 AGL1879 AGL 1879 thaliana Proteins Arabidopsis Proteins Arabidopsis thaliana Arabidopsis thaliana Proteins Hemagglutinins Plant Thale Cress Proteins Plant Hemagglutinins Arabidopsis Proteins Agglutinins Plant Plant Agglutinins Proteins Plant Phytagglutinins Plant Proteins Lectins Plant Plant Lectins 31.691723756906
10272 Prostratin 60857-08-1 ≥98% 2009-06-11 11.498044198895 prostratin SA 101A; NSC 623310; 13-O-Acetylphorbol HIV-1 AIDS NF-κB PKC T cells CD4 CXCR4 CCR5 stillingia factor S7 SFS7 13-O-acetyl-12-deoxy phorbol 11.498044198895
10011237 Protein Phosphatase 2A C subunit (human recombinant; L309 deletion) Exclusive - ✓ 2008-07-17 15.863112338858 protein-phosphatase-2a-c-subunit-human-recombinant-l309-deletion PP2A Cα; PP2A Δ309; PP2A L309 proteins phosphatases serine threonine cellular tumors enzyme kinetics regulations substrates phosphorylasion PP2As octahistidine-tag streptactin-tag 15.863112338858
10010896 Protein Tyrosine Phosphatase 1B (human recombinant) - ≥95% 2008-08-25 4.084475138121 protein-tyrosine-phosphatase-1b-human-recombinant PTP1B proteins recombinant PTPs phosphates tyrosines pNPP enzymes diabetes insulin leptin signaling signalling 4.084475138121
10009506 PSD95 Polyclonal Antibody - 2007-01-03 0.414798130046 psd95-polyclonal-antibody Postsynaptic Density Protein of 95 antibodies WB western blot PDZ domain glutamate receptors signaling proteins synapse NMDAR phosphorylation proteins signalling blotting immunoblotting 0.414798130046
9000660 PtdIns-(1,2-dihexanoyl) (sodium salt) Exclusive - ≥98% ✓ 2010-09-24 10.494086492665 ptdins-1-2-dihexanoyl-sodium-salt 1051393-51-1 phosphatidylinositols triphosphates cells signaling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PLS 10.494086492665
10008099 PtdIns-(1,2-dioctanoyl) (sodium salt) - >98% 2006-01-17 15.191247040252 ptdins-1-2-dioctanoyl-sodium-salt Phosphatidylinositol C-8 (sodium salt); DOPI (sodium salt) phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 15.191247040252
10007710 PtdIns-(1,2-dipalmitoyl) (ammonium salt) - >98% 2005-12-30 15.521604115069 ptdins-1-2-dipalmitoyl-ammonium-salt DPPI (ammonium salt); Phosphatidylinositol C-16 (ammonium salt) phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 15.521604115069
9000305 PtdIns-(1-arachidonoyl, 2-arachidonoyl-d8) (ammonium salt) Exclusive - ≥95% ✓ 2009-04-20 12.389723756906 ptdins-1-arachidonoyl-2-arachidonoyl-d8-ammonium-salt arachidonic acids deuterium atoms AA GC/MS LC/MS mass spectrometry deuterateds 12.389723756906
10008390 PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt) - >98% 2009-02-03 12.612502437439 ptdins-3-4-5-p3-1-2-dihexanoyl-ammonium-salt Phosphatidylinositol-3,4,5-triphosphate C-6 (ammonium salt); DHPI-3,4,5-P3 (ammonium salt); PIP3C-16 (ammonium salt) phosphatidylinositols cell signalling pleckstrin homology protein binding PIP3 PtdIns phospholipid signal transduction C6 C-6 12.612502437439
10007764 PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt) - >98% 2005-12-30 23.622918427038 ptdins-3-4-5-p3-1-2-dioctanoyl-sodium-salt Phosphatidylinositol-3,4,5-trisphosphate (sodium salt); DOPI-3,4,5-P3 (sodium salt) phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP3 mono PIPs 23.622918427038
9000414 PtdIns-(3,4,5)-P3 (1,2-dipalmitoyl)-d62 (sodium salt) Exclusive - ≥98% ✓ 2009-09-25 12.062781555461 ptdins-3-4-5-p3-1-2-dipalmitoyl-d62-sodium-salt Phosphatidylinositol-3,4,5-trisphosphate C-16-d62 (sodium salt); DPPI-3,4,5-P3-d62 (sodium salt) phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids PIPs phosphatidylinositols triphosphates phospholipases PLC PLD analogs deuterium GC/MS internal isotopes standards GC-MS LC/MS LC-MS mass spectrometry deuterated diacyl glycerols DAG PIP3 mono di 12.062781555461
10009531 PtdIns-(3,4,5)-P3-biotin (sodium salt) Exclusive - >98% ✓ 2007-01-16 5.547145488028 ptdins-3-4-5-p3-biotin-sodium-salt Phosphatidylinositol-3,4,5-triphosphate C-8-biotin (sodium salt); PIP3-biotin phosphatidylinositols triphosphates phospholipids phophorylation intracellular signals transduction PIP2 biotinimides dioctanoyl PTEN PI3k affinity probes ligands detection transmembranes receptors nucleic acids proteins binding kinases biotins biotinylated 5.547145488028
10010383 PtdIns-(3,4,5)-P3-fluorescein (ammonium salt) Exclusive - ≥95% ✓ 2008-08-13 25.121866614048 ptdins-3-4-5-p3-fluorescein-ammonium-salt PIPs PIP3-fluorescein fluorescent PI3K PTENs phosphatidylinositol phosphates phosphorylated kinases binding proteins PIPs 25.121866614048
10007759 PtdIns-(3,4)-P2 (1,2-dihexanoyl) (sodium salt) - >98% 2005-12-30 11.691511317055 ptdins-3-4-p2-1-2-dihexanoyl-sodium-salt Phosphatidylinositol-3,4-bisphosphate C-6 (sodium salt); DHPI-3,4-P2 (sodium salt) phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono PIPs 11.691511317055
10008400 PtdIns-(3,4)-P2 (1,2-dioctanoyl) (sodium salt) - >98% 2006-11-16 14.856718232043 ptdins-3-4-p2-1-2-dioctanoyl-sodium-salt Phosphatidylinositol-3,4-bisphosphate C-8 (sodium salt); DOPI-3,4-P2 (sodium salt) phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono PIPs 14.856718232043
10008396 PtdIns-(3,5)-P2 (1,2-dihexanoyl) (sodium salt) - >98% 2008-01-21 10.494086492665 ptdins-3-5-p2-1-2-dihexanoyl-sodium-salt Phosphatidyl-3,5-bisphosphate C-6 (sodium salt); DHPI-3,5-P2 (sodium salt) phosphatidyl inositols IP3 diacylglycerol DAG PIP1 PIP2 PIP3 signal transductions phospholipases C phospholipases D PLC PLD PIPs 10.494086492665
10007763 PtdIns-(3,5)-P2 (1,2-dioctanoyl) (sodium salt) - >98% 2005-12-30 12.922753222836 ptdins-3-5-p2-1-2-dioctanoyl-sodium-salt Phosphatidylinositol-3,5-bisphosphate C-8 (sodium salt); DOPI-3,5-P2 (sodium salt) phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono PIPs 12.922753222836
10008398 PtdIns-(3,5)-P2 (1,2-dipalmitoyl) (sodium salt) - ≥98% 2007-11-28 12.947355195152 ptdins-3-5-p2-1-2-dipalmitoyl-sodium-salt Phosphatidylinositol-3,5-diphosphate C-16 (sodium salt) phosphatidylinositols diphosphates phospholipids phophorylation signal transduction IP3 diacylglycerol DAG PIP1 PIP2 PIP3 PLC PLD 12.947355195152
10008394 PtdIns-(3)-P1 (1,2-dioctanoyl) (sodium salt) - >98% 2007-06-11 23.071255477233 ptdins-3-p1-1-2-dioctanoyl-sodium-salt Phosphatidylinositol-3-monophosphate C-8 (sodium salt); DOPI-3-P1 (sodium salt) phosphatidyl inositols IP3 diacylglcerol DAG PIP1 PIP2 PIP3 transuction C phospholipase D PLC PLD signaling signalling 23.071255477233
10005616 PtdIns-(3)-P1 (1,2-dipalmitoyl)-d62 (ammonium salt) - ≥99% deuterated product 2005-12-30 11.365077157553 ptdins-3-p1-1-2-dipalmitoyl-d62-ammonium-salt DPPI-3-P-d62 (ammonium salt); Phosphatidylinositol-3-phosphate C16-d62 (ammonium salt) phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs deuterium GC/MS internal isotopes standards GC-MS LC/MS LC-MS mass spectrometry deuterated diacyl glycerols DAG PIP1 triphosphates mono 11.365077157553
10007762 PtdIns-(4,5)-P2 (1,2-dihexanoyl) (sodium salt) - >98% 2005-12-30 15.566193024861 ptdins-4-5-p2-1-2-dihexanoyl-sodium-salt Phosphatidylinositol-4,5-bisphosphate C-6 (sodium salt); DHPI-4,5-P2 (sodium salt) phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono PIPs 15.566193024861
10008115 PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (sodium salt) - >98% 2006-01-17 37.502698549724 ptdins-4-5-p2-1-2-dipalmitoyl-sodium-salt Phosphatidylinositol-4,5-diphosphate C-16 (sodium salt); DPPI-4,5-P2 (sodium salt) phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP2 mono 37.502698549724
10005615 PtdIns-(4,5)-P2 (1,2-dipamitoyl)-d62 (sodium salt) - ≥99% deuterated product 2006-01-30 12.048353166170 ptdins-4-5-p2-1-2-dipamitoyl-d62-sodium-salt Phosphatidylinositol-4,5-diphosphate C16-d62 (sodium salt); DPPI-4,5-P2-d62 (sodium salt) phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs deuterium GC/MS internal isotopes standards GC-MS LC/MS LC-MS mass spectrometry deuterated diacyl glycerols DAG PIP2 triphosphates mono di 12.048353166170
10008159 PtdIns-(4,5)-P2-biotin (sodium salt) - >98% 2006-12-21 19.631017495395 ptdins-4-5-p2-biotin-sodium-salt Phosphatidylinositol-4,5-diphosphate C-8-biotin (sodium salt) phosphatidylinositols diphosphates phospholipids phophorylation intracellular signals transduction PIP2 biotinimides dioctanoyl PTEN PI3k affinity probes ligands detection transmembranes receptors nucleic acids proteins binding kinases PIPs biotins biotinylated 19.631017495395
10010388 PtdIns-(4,5)-P2-biotin (sodium salt) Exclusive - ≥95% ✓ 2008-08-14 48.417154696132 ptdins-4-5-p2-biotin-sodium-salt PIPs PIP2 fluoresceins fluorescent PI3K PTEN probes 48.417154696132
10007757 PtdIns-(4)-P1 (1,2-dihexanoyl) (sodium salt) - >98% 2005-12-30 13.017528069862 ptdins-4-p1-1-2-dihexanoyl-sodium-salt DHPI-4-P1 (sodium salt); Phosphatidylinositol-4-phosphate C-6 (sodium salt) phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 13.017528069862
10007711 PtdIns-(4)-P1 (1,2-dioctanoyl) (ammonium salt) - >97% 2005-12-30 13.646292995900 ptdins-4-p1-1-2-dioctanoyl-ammonium-salt DOPI-4-P (ammonium salt); Phosphatidylinositol-4-phosphate C-8 (ammonium salt) phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 13.646292995900
10008050 PtdIns-(5)-P1 (1,2-dihexanoyl) (sodium salt) - >98% 2005-12-30 10.715976058931 ptdins-5-p1-1-2-dihexanoyl-sodium-salt Phosphatidylinositol-5-phosphate (sodium salt); DHPI-5-P1 (sodium salt) phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 10.715976058931
10007758 PtdIns-(5)-P1 (1,2-dioctanoyl) (ammonium salt) - >98% 2005-12-30 13.453832412522 ptdins-5-p1-1-2-dioctanoyl-ammonium-salt DOPI-5-P1 (ammonium salt); Phosphatidylinositol-5-phosphate C-8 (ammonium salt) phosphatidylinositols triphosphates cellular signals signalling transduction phospholipids phospholipases PLC PLD analogs diacyl glycerols DAG PIP1 mono 13.453832412522
10010181 Ptd(S)Ins-(3,4)-P2 (1,2-dioctanoyl) (sodium salt) - >95% 2008-01-07 10.494086492665 ptd-s-ins-3-4-p2-1-2-dioctanoyl-sodium-salt DOsPI-3,4-P2 phospholipases C PIP2 PtdIns inositols phosphate PLC phosphothiotidyls Ellmans reagent analogs PIPs 10.494086492665
10009746 PTEN (human recombinant) - ≥95% 2008-09-04 7.611226519336 pten-human-recombinant TEP1; Phosphatidylinositol 3-phosphatase; MMAC1; Phosphatase and Tensin Homology on Chromosome 10 proteins PTENs phosphatase homology tensin chromosomes enzymes lipids Sf21 cells recombinant N-terminal tumor suppressor cancers phosphoinositide hexahistidine His-tag His-tagged 7.611226519336
10005059 PTEN Polyclonal Antibody - 2005-05-04 3.935316617084 pten-polyclonal-antibody TEP1; Phosphoinositide 3-phosphatase; MMAC1; Phosphatase and Tensin Homolog on Chromosome 10 proteins antibodies antisera antiserum wb western blots blotting IHC immunohistochemistry dephosphorylates lipids AKT phosphatidylinositols triphosphates PIP3 tissues acids regulates cells division migrations apoptosis mutations cancers melanomas prostates carcinomas A431 HEK293 signals transductions cancers endocrinology immunoblotting 3.935316617084
10009747 PTEN Western Ready Control - 2007-05-30 0E-12 pten-western-ready-control TEP1; MMAC1; Phosphoinositide 3-Phosphatase; Phosphatase and Tensin Homology on Chromosome 10 western blot WB AKT phosphatidylinositol 3,4,5-triphosphate PIP3 enzyme transduction pathway endocrinology 0E-12
13294 Pyrrophenone 341973-06-6 ≥90% 2010-04-07 51.636966665119 pyrrophenone phospholipase A2 group IVA phospholipase A2 PLA2 cytosolic PLA2 cPLA2 arachidonic acid AA prostaglandins PG leukotrienes LT inhibitors PGE2 LTB4 blood secretory type PLA2 sPLA2 inflammation inhibition inhibits inflammatory Pyrrolidines 51.636966665119
10009504 Raf-1 (Phospho-Ser301) Polyclonal Antibody - 2006-12-21 6.733631062001 raf-1-phospho-ser301-polyclonal-antibody phospho-specific antibodies proteins WB western blots blotting signal transduction Ras protein kinase MEK ERK phosphorylation Raf serine threonine cellular proliferation phospho-specific immunoblotting 6.733631062001
10009505 Raf-1 (Phospho-Ser642) Polyclonal Antibody - 2006-12-22 13.467262124002 raf-1-phospho-ser642-polyclonal-antibody phospho-specific antibodies proteins WB western blot blotting signal transduction Ras protein kinase MEK ERK phosphorylation Raf serine threonine cellular proliferation immunoblotting 13.467262124002
13346 Rapamycin 53123-88-9 ≥95% 2009-10-21 74.028345951845 rapamycin Sirolimus immunosuppresssants transplants rejection inhibitors IL-2 lymphocytes B cells T FKBP12 mTOR mTORC1 cancer adipogenesis diabetes tuberous sclerosis cardiovascular diseases 74.028345951845
10009411 Ribosomal S6 Kinase 2 Polyclonal Antibody - 2006-11-28 0.435082872928 ribosomal-s6-kinase-2-polyclonal-antibody RSK2 wb western blotting blots antibodies p90 kinases RSK1 RSK2 RSK3 RSK4 downstream members extracellular signal-regulated ERK/MAPK cascade humans Coffin-Lowry syndrome mental retardation growth deficits defects tonic regulation GPCRs G protein-coupled signalling immunoblotting 0.435082872928
13300 Ro 31-6045 113963-68-1 ≥98% 2009-07-28 4.430248618784 ro-31-6045 Bisindolylmaleimide V PKC kinase inhibitors S6K mitogen-stimulated proteins p70 p85 protein kinases C 4.430248618784
13333 Ro 31-7549 (acetate) 138516-31-1 98% 2009-07-30 27.117476979742 ro-31-7549-acetate Bisindolylmaleimide VIII, acetate PKC isozyme inhibitors phospholipases cells signalling signaling SH-SYSY neuroblastoma 125313-65-7 inhibits inhibitions 27.117476979742
13334 Ro 31-8220 (mesylate) 138489-18-6 98% 2009-10-28 32.128184162063 ro-31-8220-mesylate Bisindolylmaleimide IX bisindolylmaleimide inhibitor protein kinase C PKC PKC-α PKC-βI PKC-βII PKC-γ PKC-ε PKA CaM kinase II glycogen synthase kinase-3 GSK-3 Ro318220 GSK3 125314-64-9 Ro-31-8220 75-75-2 32.128184162063
13343 RSC-3388 337307-06-9 ≥95% 2010-02-15 11.150023155671 rsc-3388 cytosolic phospholipases A2 cPLA2 cPLA2α arachidonic acids eicosanoids platelet-activating factors PAF inhibitors inhibits inhibition inflammation dermatitis acrylamides 11.150023155671
13067 SB 203580 152121-47-6 ≥98% 2009-01-14 24.996011049724 sb-203580 RWJ 64809; PB 203580 MAPKs signal transduction p38 kinases cytokines inflammation immune response PI3-kinase PDK1 apoptosis inhibitors inhibits inhibition sb203580 24.996011049724
13344 SB 203580 (hydrochloride) 869185-85-3 ≥98% 2009-09-08 15.994769797422 sb-203580-hydrochloride PB 203580 (hydrochloride); RWJ 64809 (hydrochloride) inhibitors inhibits inhibitions MAPK signal transduction p38 kinase PI3 PDK1 15.994769797422
13336 SB 225002 182498-32-4 ≥95% 2009-07-08 41.543729281767 sb-225002 CXCR2 IL-8RB IL-8 CXCL8 Gro-α CXCL1 inflammation chemokines neutrophils angiogenesis inhibitors colitis chemotaxis IL8 IL8RB Groα inhibition inhibits sb225002 41.543729281767
10010247 SB 415286 264218-23-7 ≥98% 2008-10-29 8.411187845304 sb-415286 GSK3 GSK-3 PI3K signaling PI3K signalling glycogen synthase inhibitors inhibits inhibition neuron survival glycogen synthesis Chang human liver cells line potent selective sb415286 8.411187845304
13031 SB 431542 301836-41-9 ≥98% 2009-08-10 79.586427255985 sb-431542 inhibitors inhibits inhibitions TGF-β1 TGFβ1 receptors ALK5 ALK4 ALK7 ALKs BMP ALK2 ALK3 ALK6 kinases Smad fibrosis cancers renewal embryonic stems cells induced pluripotent differentiation SB431542 79.586427255985
10009557 SC-1 - ≥98% 2008-08-11 25.951436464088 sc-1 Pluripotin stem cells embryonic ras signal transduction ERK1 ERK2 ERK-1 ERK-2 PI3-kinase differentiation self-renewal selfrenewal SC1 SC 1 25.951436464088
10010267 SC-514 354812-17-2 ≥98% 2009-08-07 34.245933701657 sc-514 SC514 SC 514 inhibitors inhibits inhibitions IκB kinase IkB IKK2 NF-κB NFκB IL-1β IL1β genes expressions IL-6 IL6 IL-8 IL8 COX-2 COX2 iNOS LPS smooth muscles cells TLR2 TNF astrocytes 34.245933701657
13332 (S)-Glycyl-H-1152 (hydrochloride) Exclusive 913844-45-8 ≥98% ✓ 2010-01-27 52.416022099447 -s-glycyl-h-1152-hydrochloride Rho Kinase Inhibitor IV Rho kinases ROCK-I p160ROCK ROCK-II G protein Rho cytoskeletons adhesions proliferation smooth muscles contraction stem cells inhibitors inhibition inhibited Fasudil hydrochloride ROCK IV h1152 h-1152 h 1152 52.416022099447
10007653 (S)-H-1152 (hydrochloride) 451462-58-1 ≥95% 2010-02-25 11.091491712707 -s-h-1152-hydrochloride Rho kinase ROCK cytoskeletal cytoskeleton smooth muscles contractions vasoconstriction neurons neurite inhibitors Y-27632 HA-1077 PKA PKC MLCK H1152 H 1152 inhibition inhibits 451462-58-1 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine H-7 H 7 h1152 h-1152 h 1152 11.091491712707
10009312 SKF-96365 (hydrochloride) 130495-35-1 >98% 2007-01-19 31.912220994475 skf-96365-hydrochloride calcium antagonists voltage-gated inhibits inhibitors inhibition acetylcholine-induced depolarization smooth muscles platelets neutrophils SFK9635 Ach-induced HCl neurochemistry 31.912220994475
10007974 SLF Exclusive - >98% ✓ 2006-04-14 18.704125230202 slf Synthetic Ligand of FKBP FK-506 synthetic binding proteins FKBP12 ligands immunosuppressants inhibits calcium/calmodulin-dependent phosphatases calcineurins T-cells cell-permeable analogs homodimers heterodimers dimerization ligand-specific fusion signaling monomers 10-atoms linkers Fas 18.704125230202
10822 SMAD1/5/8/9 Polyclonal Antibody - 2011-04-14 1.361325966850 smad1-5-8-9-polyclonal-antibody WBs western blots immunoblotting SMADs 1 5 8 9 SMAD-1-5-8-9 1/5/8/9 antibodies serum 1,5,8,9 1.361325966850
10821 SMAD1/5/8/9 Polyclonal Antiserum - 2011-03-31 0.300552486187 smad1-5-8-9-polyclonal-antiserum WBs western blots immunoblotting SMADs 1 5 8 9 SMAD-1-5-8-9 1/5/8/9 antibodies serum 0.300552486187
10823 SMAD2 Polyclonal Antibody - 2011-05-05 0.300552486187 smad2-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-2 SMAD 2 antibodies serum IHC immunohistochemistry TGF-β TGFβ cancers 0.300552486187
10832 SMAD3 Polyclonal Antibody - 2011-05-03 1.043093922651 smad3-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-3 SMAD 3 antibodies serum IHC immunohistochemistry TGF-β TGFβ Tcells signaling TGF-β MH1 domains DNA proteins SARA ECM apoptosis proliferation differentiation 1.043093922651
10838 SMAD4 Polyclonal Antibody - 2011-05-05 0.300552486187 smad4-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-4 SMAD 4 antibodies serum IHC immunohistochemistry TGF-β TGFβ cancers 0.300552486187
10839 SMAD6 Polyclonal Antibody - 2011-05-02 0.300552486187 smad6-polyclonal-antibody WBs western blots immunoblotting SMADs MAD SMAD-6 SMAD 6 antibodies serum IHC immunohistochemistry TGF-β TGFβ Tcells intracellular proteins signaling serine threonine apoptosis bones cancers genes signal transduction 0.300552486187
10845 SMAD7 Polyclonal Antibody - 2011-05-05 0.300552486187 smad7-polyclonal-antibody WBs western blots immunoblotting SMADs SMAD-7 SMAD 7 antibodies serum TGF-β TGFβ Tcells 0.300552486187
10840 SMAD7 Polyclonal Antibody (azide-free) - 2011-05-05 0.300552486187 smad7-polyclonal-antibody-azide-free WBs western blots immunoblotting SMADs SMAD-7 SMAD 7 antibodies serum TGF-β TGFβ Tcells 0.300552486187
10012555 Sodium Hydrogen Sulfide (hydrate) 207683-19-0 ≥65% 2009-09-03 27.867152308846 sodium-hydrogen-sulfide-hydrate Sodium Hydrosulfide; NSC 158264; NaHS hydrogen sulfide H2S donor inflammation oxidative stress cardiocascular neurological neurons pulmonary leukocytes neutrophils pain 1310-76-5 64568-18-9 111883-06-8 16721-80-5 27.867152308846
10010466 SP 600125 129-56-6 ≥98% 2009-01-07 12.446795580111 sp-600125 1PMV; Pyrazolanthrone; NSC 75890 c-Jun cJun JNKs inhibitors inhibits inhibition reversible cell-permeable cells COX-2 COX2 MAP kinase MAPK genes expressions apoptosis autophagy differentiation IL-10 IL10 TNF-α TNFα IFN-γ IFNγ T-cells Tcells HeLa sp600125 12.446795580111
13337 ST638 107761-24-0 ≥98% 2010-09-21 23.765232833464 st638 tyrosine kinases inhibitors inhibits inhibition cell signaling signalling receptors tumor necrosis factor phosphorylation TNF-α phorbol myristate acetate PMA cardiac fibroblasts TNFα TNF α TNFalpha TNF.alpha. 23.765232833464
9000631 Stearoyl Serotonin Exclusive 67964-87-8 ≥98% ✓ 2010-05-18 5.675059194949 stearoyl-serotonin N-arachidonoyl serotonin AA-5-HT AA-5HT antagonists fatty acids amide hydrolase FAAH transient receptors potential vanilloid-type 1 channels TRPV1 pain capsaicin ethanolamine anandamide AEA Hydrolase Desaturase Stearoyl-CoA Stearoyl-CoA Desaturase Stearoyl CoA Desaturase Desaturase Stearyl-CoA Stearyl-CoA Desaturase Stearyl CoA Desaturase Desaturase Stearate Stearate Desaturase Desaturase delta-9 delta-9 Desaturase 5.675059194949
13338 SU 6656 330161-87-0 ≥95% 2009-08-04 26.723723756906 su-6656 inhibitors Src kinases Src Yes Lyn Fyn cells growth development nervous system fibrosis cancers inhibits inhibition CNS SU6656 26.723723756906
10007565 Tetradecyl Phosphonate 4671-75-4 >98% 2005-10-17 42.891120757695 tetradecyl-phosphonate pan-antagonists LPA receptors lysophosphatic acids lipids signalling molecules hydrolysis lysophospholipase D autotoxin signals GPCRs G-protein coupled LPA1/EDG-2 LPA2/EDG-4 LPA3/EDG-7 LPA4/GPR23 activates activation PPAR.gamma. peroxisomes proliferator-activated inhibits inhibition LPA-induced calcium mobilization activates reporter 42.891120757695
10398 TG003 New 300801-52-9 ≥95% 2011-08-17 2.384543310394 tg003 inhibitors CDC kinasesTG 003 TG-003 TG3 TG-3 TG 3 Cdc2-like kinases Clks serine/arginine-rich proteins splicing RNA Clk1/Sty Clk4 serine rich pre-mRNA Xenopus arginine SR mRNA Sty Clk1 CLk2 Clk3 Clk4 benzothiazole inhibition inhibits inhibitor SF2 SF2/ASF ASF 2.384543310394
10522 Thapsigargin New 67526-95-8 ≥97% 2011-09-23 62.429183331396 thapsigargin calcium, ATPases, sarco/endoplasmic calcium ATPases SERCAs cells signaling activation histamine cancers tumorigenesis inflammation reticula sarcoplasmic endoplasmic 62.429183331396
13237 Thiamet G Exclusive 1009816-48-1 ≥97% ✓ 2009-06-25 39.087651933701 thiamet-g inhibitors inhibits inhibitions tau alzheimers disease O-GlcNAc OGlcNAc O-GlcNAcase OGlcNAcase O-GlcNAcylation OGlcNAcylation Thiamet-G 39.087651933701
700240 Total Phosphatidic Acid Assay Kit - 2009-08-24 66.333977900552 total-phosphatidic-acid-assay-kit PA Assay Kit assays kits measures fluorescence-based cells cellular phospholipids phosphatidate membranes storage de novo synthesis phospholipases PLD PLA hydrolysis phosphodiesters phosphatidylcholines PC phosphorylation diacylglycerol DAG DAGK lysophosphatidic LPA lysoPA-acyltransferase LPAAT phosphates phosphohydrolases LPPs intracellular signal transduction mammalian rapamycin mTOR signaling cycle progression growth disregulation human diseases cancers bacterial FKBP12 Raf-1 kinases sphingosines cAMP Adenosines 3',5' cyclic mononucleotides phosphodiesterases 4A1 translocation proteins PKC tyrosines SHP-1 guanine nucleotides Son of sevenless glycerol-3-phosphate oxidized oxidases hydrogen peroxides H2O2 peroxidases ADHP 10-acetyl-3,7-dihydroxyphenoxazines resorufin 66.333977900552
10855 TRAF2 Monoclonal Antibody (Clone 33A1293) - 2011-05-06 0E-12 traf2-monoclonal-antibody-clone-33a1293 TRAF 2 TRAF-2 WBs western blots TNF tumors necrosis antibodies signal transduction proteins blotting immunoblotting 0E-12
10872 TRAF3 Polyclonal Antibody - 2011-05-26 1.282707182320 traf3-polyclonal-antibody TRAF 3 TRAF-3 WBs western blots TNF tumors necrosis antibodies signal transduction proteins blotting immunoblotting 1.282707182320
10873 TRAF5 Monoclonal Antibody (Clone 55A219) - 2011-05-26 1.282707182320 traf5-monoclonal-antibody-clone-55a219 TRAF 5 TRAF-5 WBs western blots TNF tumors necrosis antibodies signal transduction proteins blotting immunoblotting 1.282707182320
10894 TRAF6BP Polyclonal Antibody - 2011-05-26 1.282707182320 traf6bp-polyclonal-antibody T6BP; TAX1BP1; TRAF6 Binding Protein; TAX1-binding protein TRAF 6BP TRAF-6BP WBs western blots TNF tumors necrosis antibodies signal transduction proteins blotting immunoblotting 1.282707182320
10874 TRAF6 Polyclonal Antibody - 2011-05-26 1.282707182320 traf6-polyclonal-antibody TNF Receptor-Associated Factor 6 TRAF 6 TRAF-6 WBs western blots TNF tumors necrosis antibodies signal transduction proteins blotting immunoblotting 1.282707182320
10010237 Triciribine 35943-35-2 >98% 2007-09-11 3.783425414365 triciribine Tricyclic Nucleoside; NSC 154020; API 2 Akt cancers inhibitors inhibition inhibits Akt-1 Akt1 Akt-2 Akt2 Akt-3 Akt3 PI3-kinase PI3kinase PI3K PI-3-kinase phosphorylation activation signalling pathway signaling 3.783425414365
70970 U-0126 109511-58-2 >98% 2007-11-20 22.161657458563 u-0126 U0126 MAPK MAP Kinases inhibitors inhibits inhibition MEK MEK1 MEK2 signal transduction ATP adenosine triphosphate U 0126 22.161657458563
10009152 Valinomycin 2001-95-8 >95% 2007-01-22 16.803867403315 valinomycin NSC 122023 Ionophore potassium ion antibiotic apoptosis cyclododecadepesipeptide Streptomyces efflux phosphatidylserine membrane translocation caspase-3 activation 16.803867403315
13671 Wortmannin-Rapamycin Conjugate - ≥98% 2010-05-11 26.090529977491 wortmannin-rapamycin-conjugate phosphoinositides 3-kinases PI3K mammalian targets mTOR cancers inhibitors inhibits inhibition complex 1 mTORC1 tumors bevacizumab VEGF colons A498 HT29 53123-88-9 sirolimus prodrug linkers links 19545-26-7 KY 12420 renal phosphatidyl inositols 26.090529977491
11179 WSP-1 New - ≥95% 2012-01-17 96.371856967464 wsp-1 Washington State Probe-1 hydrogen sulfide H2S fluorescent probes immunological immune neurological cardiovascular pulmonary mammals disulfide cells benzoithiolone fluorophore WSP1 WSP 1 96.371856967464
10008883 WST-1 Cell Proliferation Assay Kit - 2006-09-07 66.456081507962 wst-1-cell-proliferation-assay-kit assays cells proliferation induction inhibitors inhibition inhibits growth factors signaling signalling molecules cycles regulatory factors cytokines mitogens drugs microtiter plates in vitro enzymes enzymatic cleavage tertrazolium salts formazan cellular mitochondrial dehydrogenases screen kits measures measurements cancers cell-based assay cell based assay cba 66.456081507962
10010199 WST-8 Cell Proliferation Assay Kit - 2007-09-11 77.440888409607 wst-8-cell-proliferation-assay-kit assays cells proliferation induction inhibitors inhibition inhibits growth factors signaling signalling molecules cycles regulatory factors cytokines mitogens drugs microwell plates in vitro enzymes enzymatic cleavage tertrazolium salts formazan cellular mitochondrial dehydrogenases screen kits measures measurements special:quarterly specialdiscount:50 specialstart:2007-12-01 specialend:2008-02-29 cell-based assay cell based assay cba 77.440888409607
13604 WYE-354 New 1062169-56-5 ≥98% 2012-01-12 89.187240638428 wye-354 mTOR mTORC1 mTORC2 inhibitors inhibits inhibition PI3K cancers cells growth PTENs tumors rapamycin complex 1 2 G1 phosphatidylinositol 3-kinase α PI3Kα kinases 89.187240638428
13639 WZ811 55778-02-4 ≥95% 2010-03-22 14.105262430939 wz811 CXC chemokines receptors CXCR4 stromal cell-derived factor-1 SDF-1 CXCL12 hematopoietic stem cells chemotaxis lymphocytes growth metastasis cancers T cells HIV infection inhibitors antagonist cAMP Matrigel invasion breast cancer adenocarcinoma inhibition alpha-Aminotoluene alpha Aminotoluene Phenylmethylamine Benzylamines 14.105262430939
13596 XAV939 284028-89-3 ≥98% 2009-12-03 13.798674033149 xav939 Wnt cancers β-catenin APC axin GSK3 poly-ADP-ribosylation tankyrases TNKS1 TNKS2 inhibitors inhibition inhibits 13.798674033149
10010200 XTT Cell Proliferation Assay Kit - 2007-09-11 55.448673442255 xtt-cell-proliferation-assay-kit assays cells proliferation induction inhibitors inhibition inhibits growth factors signaling signalling molecules cycles regulatory factors cytokines mitogens drugs microtiter plates in vitro enzymes enzymatic cleavage tertrazolium salts formazan cellular mitochondrial dehydrogenases screen kits measures measurements special:quarterly specialdiscount:50 specialstart:2007-12-01 specialend:2008-02-29 cell-based assay cell based assay cba 55.448673442255
10005583 Y-27632 (hydrochloride) 129830-38-2 >98% 2007-11-29 184.328121546961 y-27632-hydrochloride Y27632 inhibitors inhibit inhibition Rho ROCK ROCK-II ROCKII PRK2 smooth muscle contraction cell adhesion signal transduction kinase phosphorylation HCl competative Y 27632 146986-50-7 184.328121546961
13246 YM-58483 223499-30-7 ≥98% 2009-11-16 2.185497237569 ym-58483 BTP 2 calcium channels leukocytes leukotrienes eicosanoids inflammation asthma allergy IL-2 IL-4 lymphocytes eosinophils NF-AT CRACs CysLTs interleukin-4 BTP2 BTP-2 CysLT 2.185497237569
13665 YS121 Exclusive 916482-17-2 ≥98% ✓ 2010-04-02 20.386180939226 ys121 Microsomal Prostaglandin E2 Synthase-1 mPGES-1 cyclooxygenase-2 COX-2 PGE2 inflammation fever pain 5-Lipoxygenase 5-LO leukotrienes LTs inhibitors LTB4 cyclooxygenase-1 COX-1 LTC4 LTD4 LTE4 inhibition Pyrimidines inhibits PGs YS 121 YS-121 20.386180939226
10010421 Zaprinast 37762-06-4 ≥98% 2008-09-18 5.375156537752 zaprinast 2-(o-Propoxyphenyl)-8-azapurin-6-one; M&B 22,948 sildenafil viagra phophodiesterase cGMP PDE5 GRP35 inhibitors inhibits inhibition M&B 22948 55122-20-8 5.375156537752
71800 (Z)-Guggulsterone 39025-23-5 ≥98% 2009-12-01 0.167679558011 -z-guggulsterone anti flammatory cancers FXR bile acids LDL cholesterol tumors IL-6 STAT3 VEGF Akt 0.167679558011
10010367 ZM 336372 208260-29-1 >98% 2008-01-09 2.260457056755 zm-336372 Raf-1 c-raf inhibitors inhibition inhibits cancers anti-cancer MEK 1/2 MAPK signals transductions proliferations cells cycles ERK1 ERK2 ERK1/2 ATP adenosine triphosphate signaling carcinoid tumor 2.260457056755
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