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Cayman Chemical Medicinal Chemists have an average of 15 years of experience in projects within various therapeutic areas such as CNS, Cardiovascular, Inflammation, Cancer, Antibacterial, Dermatology, Allergy, and Respiratory. Our experiences include lead identification and optimization, providing and utilizing SAR analysis, structure-based drug design, computational ADMET modeling, 3D pharmacophore modeling, virtual screening, and protein homology modeling, producing many preclinical as well as clinical drug candidates.
Medicinal chemistry capabilities:
- Hit to lead chemistry
- Optimization of in vitro pharmacology (SAR)
- ADMET optimization
- Patent exemplification
- Parallel Medicinal Chemistry
- Assay development
- Back-up series development
- Batch synthesis for API
- Scale-up synthesis of intermediates for singleton and parallel analogs and for preclinical studies
- Route design and development
Molecular modeling capabilitites:
- Structure based drug design
- Target analysis
- Virtual screening
- Database analysis
- Biopharmaceutical property calculation
- QSAR modeling
For more information on any of these
services please contact our sales department at 1-800-364-9897 or email
us at sales@caymanchem.com |
