FABP1 (rat recombinant)
Item № 10005200
Purity ≥95%

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  • L-FABP
  • Liver-FABP
  • Liver-Fatty Acid Binding Protein
  • Fatty Acid Binding Protein 1

Fatty acid binding protein 1 (FABP1) is one of nine known cytosolic FABPs ranging in size from 14-15 kDa containing 127-132 amino acids.1 FABP1 is composed of ten antiparallel β strands that form a barrel with a bigger binding pocket than the other FABPs allowing it to accommodate two fatty acids. Expression of FABP1 is decreased in hepatoblastoma and hepatocellular carcinoma making the protein a potential tumor marker. Moreover, studies have suggested FABP1 as a potential biomarker for both liver and kidney injury.1 Cayman’s FABP1 has been functionally characterized by a fluorescence displacement assay using the fluorescent fatty acid analogue 11-(dansyl amino)undecanoic acid (DAUDA). Both arachidonic acid and oleic acid effectively displace DAUDA from the FABP binding pocket in a concentration-dependent manner.

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Technical Information
  • L-FABP
  • Liver-FABP
  • Liver-Fatty Acid Binding Protein
  • Fatty Acid Binding Protein 1
Purity ≥95%
Source recombinant N-terminal hexahistidine-tagged protein expressed in E. coli
MW 18.3 kDa
Formulation A solution in 50 mM of sodium phosphate, pH 7.2, containing 20% glycerol and 100 mM sodium chloride

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -80°C
Shipping Dry ice in continental US; may vary elsewhere
Stability As supplied, 1 year from the QC date provided on the Certificate of Analysis, when stored properly
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Additional Information

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References & Background Reading
Product Description References

1. Zimmerman, A.W., and Veerkamp, J.H. New insights into the structure and function of fatty acid-binding proteins. Cell Mol Life Sci 59 1096-1116 (2002).

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