Item № 10006320
CAS № 152-43-2
Purity ≥98%
100 mg $28.00 $0.00
250 mg $67.00 $0.00
500 mg $126.00 $0.00
1 g $224.00 $0.00

Pricing updated 2016-04-29. Prices are subject to change without notice.

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  • Estrovis®
  • Ethynyl Estradiol-3-cyclopentyl ether
  • W 3566

Quinestrol is a synthetic estrogen that is effective in hormone replacement therapy.1,2 It is a 3-cyclopentyl ether of ethynyl estradiol. After gastrointestinal absorption, it is stored in adipose tissue, where it is slowly released and metabolized in the liver to its active form, ethinyl estradiol. Quinestrol has found limited use in suppressing lactation in postpartum women and, in combination with synthetic progestogens, as contraceptive therapy, although additional studies are needed for both applications.

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Technical Information
Formal Name 3-(cyclopentyloxy)-19-norpregna-1,3,5(10)-trien-20-yn-17α-ol
CAS Number 152-43-2
  • Estrovis®
  • Ethynyl Estradiol-3-cyclopentyl ether
  • W 3566
Molecular Formula C25H32O2
Formula Weight 364.5
Purity ≥98%
Formulation A crystalline solid
λmax 202, 281 nm
SMILES C[C@@]12[C@@]([H])(CC[C@@]2(O)C#C)[C@]([C@]3([H])CC1)([H])CCC4=C3C=CC(OC5CCCC5)=C4
InChI Code 1S/C25H32O2/c1-3-25(26)15-13-23-22-10-8-17-16-19(27-18-6-4-5-7-18)9-11-20(17)21(22)12-14-24(23,25)2/h1,9,11,16,18,21-23,26H,4-8,10,12-15H2,2H3/t21-,22-,23+,24+,25+/m1/s1

WARNING - This product is not for human or veterinary use.

Shipping & Storage
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
Stability As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
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References & Background Reading
Product Description References

1. Baumgardner, S.B., Condrea, H., Daane, T.A., et al. Replacement estrogen therapy for menopausal vasomotor flushes. Comparison of Quinestrol and conjugated estrogens.. Obstet Gynecol 51(4) 445-452 (1978).

2. Skouby, S.O. Criteria for the selection of an optimal estrogen replacement.. Gynecol Endocrinol 15 60-67 (2001).

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